Rafi Ahmed, PhD

Research Program

Cancer Immunology
Phone Number

404-727-3571
Email Address

rahmed@emory.edu

Biography

Rafi Ahmed, PhD, is a professor in the Department of Microbiology and Immunology at Emory University School of Medicine. A member of the National Academy of Science, Dr. Ahmed is a world-renowned immunologist whose work during the past decade has been highly influential in shaping our current understanding of memory T cell differentiation and anti-viral T and B cell immunity.

Dr. Ahmed is co-leader of the Cancer Immunology Research Program at Winship Cancer Institute of Emory University in Atlanta, Georgia. He is a Georgia Research Alliance Eminent Scholar and a fellow of the Academy of Immuno-Oncology.

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Titles & Roles

Professor, Department of Microbiology and Immunology

Emory University School of Medicine
Vaccine Center Director

Emory Vaccine Center
Co-Leader, Cancer Immunology Research Program

Winship Cancer Institute of Emory University
Investigator

Emory Center for AIDS Research

Research

The long-term goal of Dr. Ahmed's research is to understand the mechanisms of B and T cell immunological memory and to use this information to develop new vaccines for the prevention and treatment of disease. The Ahmed laboratory uses highly sophisticated cellular and molecular techniques to study antigen-specific immunological memory in murine, primate, and human systems. A major area of focus is identifying cellular molecules that regulate the generation and maintenance of CD8 and CD4 T cell and humoral immunity. One such molecule is mTOR that they recently identified as a major regulator of memory CD8 T cell differentiation.

Another approach of the Ahmed laboratory is to understanding humoral memory development and maintenance. They have co-developed a novel method for rapidly generating human monoclonal antibodies after vaccination and have shown that broadly cross-reactive antibodies that recognize multiple influenza viruses can be generated after influenza vaccination in humans. These studies and those currently ongoing, which include understanding the mechanisms that regulate the development of neutralizing antibody, give rise to the possibility that a universal influenza vaccine could be developed in the near future.

Grants

View Grants

Grant Number	Title
1K08AI166837-01A1	Characterization of brain metastasis-specific CD8+ T cells
1T32AI157855-01A1	Emory Training Program in Translational Research to End the HIV Epidemic
1U54CA274513-01	Genomic and Microenvironmental Determinants, Temporal Dynamics, and Treatment Efficacy of Radiation-Based Combination Therapies
1U54CA274513-01	Genomic and Microenvironmental Determinants, Temporal Dynamics, and Treatment Efficacy of Radiation-Based Combination Therapies
1U54CA274513-01	P3: Molecular Mechanisms Underlying Therapy Response to Radiation and Immune Checkpoint BlockadeýSUBAWARD
2U19AI057266-21	Vaccine and Infection Induced Immunity in the Young and Aged
5K08AI166837-02	Characterization of brain metastasis-specific CD8+ T cells
5K12CA237806-05	Emory Clinical Oncology Career Development Award K12 Program
5T32AI157855-02	Emory Training Program in Translational Research to End the HIV Epidemic
5T32AI157855-03	Emory Training Program in Translational Research to End the HIV Epidemic
5U54CA274513-02	Genomic and Microenvironmental Determinants, Temporal Dynamics, and Treatment Efficacy of Radiation-Based Combination Therapies
5U54CA274513-02	Genomic and Microenvironmental Determinants, Temporal Dynamics, and Treatment Efficacy of Radiation-Based Combination Therapies
5U54CA274513-02	P3: Molecular Mechanisms Underlying Therapy Response to Radiation and Immune Checkpoint BlockadeýSUBAWARD

Publications

Title/Journal	Authors	Publication Date
An early precursor CD8⁺ T cell that adapts to acute or chronic viral infection. Nature	DT McManus, RM Valanparambil, CB Medina, CD Scharer, DJ McGuire, E Sobierajska, Y Hu, DY Chang, A Wieland, J Lee, TH Nasti, M Hashimoto, JL Ross, N Prokhnevska, MA Cardenas, AL Gill, EC Clark, K Abadie, AJ Kumar, J Kaye, BB Au-Yeung, HY Kueh, HT Kissick, R Ahmed	04/01/2025
Anti-Ebola virus mAb 3A6 protects highly viremic animals from fatal outcome via binding GP_(1,2) in a position elevated from the virion membrane. Nature communications	KM Hastie, ZL Salie, Z Ke, PJ Halfmann, LE DeWald, S McArdle, A Grinyó, E Davidson, SL Schendel, C Hariharan, MJ Norris, X Yu, C Chennareddy, X Xiong, M Heinrich, MR Holbrook, B Doranz, I Crozier, Y Kawaoka, LM Branco, JH Kuhn, JAG Briggs, G Worwa, CW Davis, R Ahmed, EO Saphire	02/03/2025
Meeting report: Considerations for trial design and endpoints in licensing therapeutic HPV16/18 vaccines to prevent cervical cancer. Vaccine	PM Dull, SL Achilles, R Ahmed, RV Barnabas, NG Campos, K Chirgwin, JA Cohen, S de Sanjosé, J Doorbar, MH Einstein, CI Emerson, SL Gottlieb, A Hildesheim, Y Qiao, P Ruff, JN Sampson, P Sasieni, M Schiffman, H Shin, MA Stanley, CL Trimble, N Wentzensen, AB Riemer, JT Schiller, AR Kreimer	11/14/2024
Characteristics of Lung Cancer Patients With Asymptomatic or Undiagnosed SARS-CoV-2 Infections. Clinical lung cancer	M Somisetty, PC Mack, CY Hsu, Y Huang, JE Gomez, AM Rodilla, J Cagan, SC Tavolacci, JM Carreño, R Brody, AC Moore, JC King, NC Rohs, C Rolfo, PA Bunn, JD Minna, S Bhalla, F Krammer, A García-Sastre, JC Figueiredo, E Kazemian, KL Reckamp, AA Merchant, M Nadri, R Ahmed, SS Ramalingam, Y Shyr, FR Hirsch, DE Gerber	11/01/2024
Mechanical force regulates ligand binding and function of PD-1. Nature communications	K Li, P Cardenas-Lizana, J Lyu, AV Kellner, M Li, P Cong, VE Watson, Z Yuan, E Ahn, L Doudy, Z Li, K Salaita, R Ahmed, C Zhu	09/27/2024
Chronic viral infection alters PD-1 locus subnuclear localization in cytotoxic CD8⁺ T cells. Cell reports	C Sacristán, BA Youngblood, P Lu, APR Bally, JX Xu, K McGary, SL Hewitt, JM Boss, JA Skok, R Ahmed, ML Dustin	08/27/2024
Intensity-Modulated Reirradiation Therapy With Nivolumab in Recurrent or Second Primary Head and Neck Squamous Cell Carcinoma: A Nonrandomized Controlled Trial. JAMA oncology	NF Saba, SJ Wong, T Nasti, AA McCook-Veal, MW McDonald, WA Stokes, AM Anderson, A Ekpenyong, M Rupji, M Abousaud, S Rudra, JE Bates, JS Remick, NP Joshi, NM Woody, M Awan, JL Geiger, A Shreenivas, J Samsa, MC Ward, NC Schmitt, MR Patel, KA Higgins, Y Teng, CE Steuer, DM Shin, Y Liu, R Ahmed, SA Koyfman	07/01/2024
Pembrolizumab and low-dose, single-fraction radiotherapy for patients with relapsed or refractory multiple myeloma: a prospective, single-centre, single-group, open-label, phase 2 pilot trial in the USA. The Lancet. Haematology	MK Khan, TH Nasti, JY Qian, TJ Kleber, JM Switchenko, JL Kaufman, AJ Nooka, MV Dhodapkar, ZS Buchwald, D Obiekwe, S Lonial, R Ahmed	07/01/2024
Time-Dependent Effects of Clinical Interventions on SARS-CoV-2 Immunity in Patients with Lung Cancer. Vaccines	PC Mack, CY Hsu, AM Rodilla, JE Gomez, J Cagan, Y Huang, S Tavolacci, RM Valanparambil, N Rohs, R Brody, B Nichols, JM Carreño, S Bhalla, C Rolfo, DE Gerber, A Moore, JC King, R Ahmed, JD Minna, PA Bunn, A García-Sastre, F Krammer, FR Hirsch, Y Shyr	06/26/2024
Platinum-Based Chemotherapy Attenuates the Effector Response of CD8 T Cells to Concomitant PD-1 Blockade. Clinical cancer research : an official journal of the American Association for Cancer Research	A Mariniello, TH Nasti, DY Chang, M Hashimoto, S Malik, DT McManus, J Lee, DJ McGuire, MA Cardenas, P Umana, V Nicolini, R Antia, A Saha, Z Buchwald, H Kissick, E Ghorani, S Novello, D Sangiolo, GV Scagliotti, SS Ramalingam, R Ahmed	05/01/2024
Michael Oldstone (1932-2023): Pioneer in viral pathogenesis, historian and author. Proceedings of the National Academy of Sciences of the United States of America	R Ahmed	04/09/2024
Harnessing CD8 T cell responses using PD-1-IL-2 combination therapy. Trends in cancer	M Hashimoto, SS Ramalingam, R Ahmed	04/01/2024
Severe disease during both primary and secondary dengue virus infections in pediatric populations. Nature medicine	C Aggarwal, H Ahmed, P Sharma, ES Reddy, K Nayak, M Singla, D Maheshwari, YM Chawla, H Panda, RC Rai, S Gunisetty, L Priyamvada, SK Bhaumik, SF Ahamed, R Vivek, P Bhatnagar, P Singh, M Kaur, K Dixit, S Kumar, K Gottimukkala, K Saini, P Bajpai, GP Sreekanth, S Mammen, A Rajan, VP Verghese, AM Abraham, P Shah, K Alagarasu, T Yu, CW Davis, J Wrammert, A Ansari, R Antia, SK Kabra, GR Medigeshi, R Ahmed, R Lodha, A Shet, A Chandele, K Murali-Krishna	03/01/2024
Reversible, tunable epigenetic silencing of TCF1 generates flexibility in the T cell memory decision. Immunity	K Abadie, EC Clark, RM Valanparambil, O Ukogu, W Yang, RM Daza, KKH Ng, J Fathima, AL Wang, J Lee, TH Nasti, A Bhandoola, A Nourmohammad, R Ahmed, J Shendure, J Cao, HY Kueh	02/13/2024
Early generation of a precursor CD8 T cell that can adapt to acute or chronic viral infection. Research square	DT McManus, RM Valanparambil, CB Medina, Y Hu, CD Scharer, E Sobierajska, DY Chang, A Wieland, J Lee, TH Nasti, M Hashimoto, JL Ross, N Prokhnevska, MA Cardenas, AL Gill, EC Clark, K Abadie, HY Kueh, J Kaye, BB Au-Yeung, HT Kissick, R Ahmed	02/12/2024
Functional impairment of "helpless" CD8 ⁺ memory T cells is transient and driven by prolonged but finite cognate antigen presentation. bioRxiv : the preprint server for biology	V van der Heide, B Davenport, B Cubitt, V Roudko, D Choo, E Humblin, K Jhun, K Angeliadis, T Dawson, G Furtado, A Kamphorst, R Ahmed, JC de la Torre, D Homann	01/26/2024
Characterisation of clinical response and transcriptional profiling of proliferating CD8 T cells in the blood of cancer patients after PD-1 monotherapy or combination therapy. BMJ oncology	RC Obeng, TH Nasti, K Martens, P Li, A Mariniello, DY Chang, CS Eberhardt, D McGuire, H Kissick, C Daugherty, Y Zhang, A Wieland, Z Chen, JM Switchenko, R Pillai, AO Kamphorst, WJ Leonard, R Ahmed, SS Ramalingam	01/01/2024
Case Reports: Chemokine and Cytokine Profiling in Patients with Herpetic Uveitis. International medical case reports journal	NV Nguyen, SL Linderman, T Fashina, M Devine, CD Conrady, JG Shantha, R Ahmed, S Yeh	01/01/2024
Anti-Ebola virus mAb 3A6 with unprecedented potency protects highly viremic animals from fatal outcome and physically lifts its glycoprotein target from the virion membrane. Research square	E Saphire, ZL Salie, Z Ke, P Halfmann, LE DeWald, S McArdle, A Grinyo, E Davidson, S Schendel, C Hariharan, M Norris, X Yu, C Chennareddy, X Xiong, M Heinrich, M Holbrook, B Doranz, I Crozier, K Hastie, Y Kawaoka, L Branco, J Kuhn, J Briggs, G Worwa, C Davis, R Ahmed	12/22/2023
Mitochondrial metabolic flexibility is critical for CD8⁺ T cell antitumor immunity. Science advances	C Chen, H Zheng, EM Horwitz, S Ando, K Araki, P Zhao, Z Li, ML Ford, R Ahmed, CK Qu	12/08/2023
The evolution and determinants of neutralization of potent head-binding antibodies against Ebola virus. Cell reports	X Yu, KM Hastie, CW Davis, RD Avalos, D Williams, D Parekh, S Hui, C Mann, C Hariharan, A Takada, R Ahmed, EO Saphire	11/28/2023
BA.5 bivalent booster vaccination enhances neutralization of XBB.1.5, XBB.1.16 and XBB.1.9 variants in patients with lung cancer. NPJ vaccines	RM Valanparambil, L Lai, MA Johns, M Davis-Gardner, SL Linderman, TO McPherson, A Chang, A Akhtar, ELB Gamarra, H Matia, AA McCook-Veal, J Switchenko, TH Nasti, F Green, M Saini, A Wieland, BA Pinsky, D Solis, MV Dhodapkar, J Carlisle, S Ramalingam, R Ahmed, MS Suthar	11/21/2023
Longitudinal nucleocapsid antibody testing reveals undocumented SARS-CoV-2 infections in patients with lung cancer. Cancer cell	AM Rodilla, RM Valanparambil, PC Mack, CY Hsu, J Cagan, SC Tavolacci, JM Carreño, R Brody, A Moore, JC King, JE Gomez, N Rohs, C Rolfo, PA Bunn, DE Gerber, JD Minna, F Krammer, SS Ramalingam, A García-Sastre, Y Shyr, R Ahmed, FR Hirsch	11/13/2023
Reciprocal transmission of activating and inhibitory signals and cell fate in regenerating T cells. Cell reports	PH Wang, RS Washburn, DL Mariuzza, WW Lin, AL Gill, R Ahmed, SL Reiner	10/31/2023
Efficacy of mRNA-1273 and Novavax ancestral or BA.1 spike booster vaccines against SARS-CoV-2 BA.5 infection in nonhuman primates. Science immunology	NK Routhu, SD Stampfer, L Lai, A Akhtar, X Tong, D Yuan, TM Chicz, RP McNamara, K Jakkala, ME Davis-Gardner, EL St Pierre, B Smith, KM Green, N Golden, B Picou, SM Jean, J Wood, J Cohen, IN Moore, N Patel, M Guebre-Xabier, G Smith, G Glenn, PA Kozlowski, G Alter, R Ahmed, MS Suthar, RR Amara	10/27/2023
Infants and young children generate more durable antibody responses to SARS-CoV-2 infection than adults. iScience	D Joshi, LE Nyhoff, VI Zarnitsyna, A Moreno, K Manning, S Linderman, AR Burrell, K Stephens, C Norwood, G Mantus, R Ahmed, EJ Anderson, MA Staat, MS Suthar, J Wrammert	10/20/2023
Characteristics and anatomic location of PD-1⁺TCF1⁺ stem-like CD8 T cells in chronic viral infection and cancer. Proceedings of the National Academy of Sciences of the United States of America	SJ Im, RC Obeng, TH Nasti, D McManus, AO Kamphorst, S Gunisetty, N Prokhnevska, JW Carlisle, K Yu, GL Sica, LE Cardozo, ANA Gonçalves, HT Kissick, HI Nakaya, SS Ramalingam, R Ahmed	10/10/2023
Light chain of a public SARS-CoV-2 class-3 antibody modulates neutralization against Omicron. Cell reports	A Patel, S Kumar, L Lai, M Keen, R Valanparambil, C Chakravarthy, Z Laughlin, F Frank, N Cheedarla, HP Verkerke, AS Neish, JD Roback, CW Davis, J Wrammert, A Sharma, R Ahmed, MS Suthar, K Murali-Krishna, A Chandele, E Ortlund	09/26/2023
Mechanical force regulates ligand binding and function of PD-1. bioRxiv : the preprint server for biology	K Li, P Cardenas-Lizana, AV Kellner, Z Yuan, E Ahn, J Lyu, Z Li, K Salaita, R Ahmed, C Zhu	08/15/2023
mRNA vaccination boosts S-specific T cell memory and promotes expansion of CD45RA_int T_EMRA-like CD8⁺ T cells in COVID-19 recovered individuals. Cell reports. Medicine	K Mayer-Blackwell, H Ryu, AS Codd, KR Parks, HR MacMillan, KW Cohen, TL Stewart, A Seese, MP Lemos, SC De Rosa, JL Czartoski, Z Moodie, LT Nguyen, DJ McGuire, R Ahmed, A Fiore-Gartland, MJ McElrath, EW Newell	08/15/2023
PD-1 blockade increases the self-renewal of stem-like CD8 T cells to compensate for their accelerated differentiation into effectors. Science immunology	AL Gill, PH Wang, J Lee, WH Hudson, S Ando, K Araki, Y Hu, A Wieland, S Im, A Gavora, CB Medina, GJ Freeman, M Hashimoto, SL Reiner, R Ahmed	08/04/2023
Molecular basis of SARS-CoV-2 Omicron variant evasion from shared neutralizing antibody response. Structure (London, England : 1993)	A Patel, S Kumar, L Lai, C Chakravarthy, R Valanparambil, ES Reddy, K Gottimukkala, P Bajpai, DR Raju, VV Edara, ME Davis-Gardner, S Linderman, K Dixit, P Sharma, G Mantus, N Cheedarla, HP Verkerke, F Frank, AS Neish, JD Roback, CW Davis, J Wrammert, R Ahmed, MS Suthar, A Sharma, K Murali-Krishna, A Chandele, EA Ortlund	07/06/2023
Low neutralizing activity of AZD7442 against current SARS-CoV-2 Omicron variants in patients with B-cell malignancies. Blood advances	A Chang, JL Koff, L Lai, VM Orellana-Noia, M Surati, AMK Leal, ML Ellis, B Wali, A Moreno, SL Linderman, CB O'Leary, PB Allen, MC Churnetski, MV Dhodapkar, MS Suthar, JB Cohen, R Ahmed	06/13/2023
Infants and young children generate more durable antibody responses to SARS-CoV-2 infection than adults. medRxiv : the preprint server for health sciences	D Joshi, LE Nyhoff, VI Zarnitsyna, A Moreno, K Manning, S Linderman, AR Burrell, K Stephens, C Norwood, G Mantus, R Ahmed, EJ Anderson, MA Staat, MS Suthar, J Wrammert	04/11/2023
Impaired SARS-CoV-2 Variant Neutralization and CD8+ T-cell Responses Following 3 Doses of mRNA Vaccines in Myeloma: Correlation with Breakthrough Infections. Blood cancer discovery	MI Azeem, AK Nooka, U Shanmugasundaram, N Cheedarla, S Potdar, RJ Manalo, A Moreno, JM Switchenko, S Cheedarla, DB Doxie, R Radzievski, ML Ellis, KE Manning, B Wali, RM Valanparambil, KT Maples, E Baymon, JL Kaufman, CC Hofmeister, NS Joseph, S Lonial, JD Roback, A Sette, R Ahmed, MS Suthar, AS Neish, MV Dhodapkar, KM Dhodapkar	03/01/2023
Risk Factors for Ebola Virus Persistence in Semen of Survivors in Liberia. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America	J Dyal, A Kofman, JZ Kollie, J Fankhauser, R Orone, MJ Soka, U Glaybo, A Kiawu, E Freeman, G Giah, HD Tony, M Faikai, M Jawara, K Kamara, S Kamara, B Flowers, ML Kromah, R Desamu-Thorpe, J Graziano, S Brown, ME Morales-Betoulle, DL Cannon, K Su, SL Linderman, M Plucinski, E Rogier, RS Bradbury, WE Secor, KE Bowden, C Phillips, MN Carrington, YH Park, MP Martin, MDP Aguinaga, R Mushi, DL Haberling, ED Ervin, JD Klena, M Massaquoi, T Nyenswah, ST Nichol, DE Chiriboga, DE Williams, SH Hinrichs, R Ahmed, BT Vonhm, PE Rollin, LJ Purpura, MJ Choi	02/08/2023
Longitudinal Analysis of the Phenotype, Transcriptional Profile, and Anatomic Location of Memory CD8 T Cell Subsets after Acute Viral Infection. Journal of virology	AL Gill, WH Hudson, RM Valanparambil, E Ahn, DJ McGuire, A Wieland, DT McManus, HT Kissick, RS Akondy, R Ahmed	01/31/2023
mTOR regulates T cell exhaustion and PD-1-targeted immunotherapy response during chronic viral infection. The Journal of clinical investigation	S Ando, CM Perkins, Y Sajiki, C Chastain, RM Valanparambil, A Wieland, WH Hudson, M Hashimoto, SS Ramalingam, GJ Freeman, R Ahmed, K Araki	01/17/2023
Route of self-amplifying mRNA vaccination modulates the establishment of pulmonary resident memory CD8 and CD4 T cells. Science immunology	M Künzli, SD O'Flanagan, M LaRue, P Talukder, T Dileepan, JM Stolley, AG Soerens, CF Quarnstrom, S Wijeyesinghe, Y Ye, JS McPartlan, JS Mitchell, CW Mandl, R Vile, MK Jenkins, R Ahmed, V Vezys, JS Chahal, D Masopust	12/09/2022
Antibody binding and neutralization of live SARS-CoV-2 variants including BA.4/5 following booster vaccination of patients with B-cell malignancies. Cancer research communications	A Chang, A Akhtar, L Lai, VM Orellana-Noia, SL Linderman, AA McCook-Veal, JM Switchenko, M Saini, RM Valanparambil, KA Blum, PB Allen, MJ Lechowicz, JT Romancik, A Ayers, A Leal, CB O'Leary, MC Churnetski, K Baird, M Kives, J Wrammert, AK Nooka, JL Koff, MV Dhodapkar, MS Suthar, JB Cohen, R Ahmed	12/01/2022
Neutralizing antibody responses in patients hospitalized with SARS-CoV-2 Delta or Omicron infection. The Journal of clinical investigation	SL Linderman, L Lai, EL Bocangel Gamarra, MS Lau, S Edupuganti, D Surie, MW Tenforde, JD Chappell, NM Mohr, KW Gibbs, JS Steingrub, MC Exline, NI Shapiro, AE Frosch, N Qadir, ME Davis-Gardner, MJ McElrath, AS Lauring, MS Suthar, MM Patel, WH Self, R Ahmed	12/01/2022
Antibody Response to COVID-19 mRNA Vaccine in Patients With Lung Cancer After Primary Immunization and Booster: Reactivity to the SARS-CoV-2 WT Virus and Omicron Variant. Journal of clinical oncology : official journal of the American Society of Clinical Oncology	RM Valanparambil, J Carlisle, SL Linderman, A Akthar, RL Millett, L Lai, A Chang, AA McCook-Veal, J Switchenko, TH Nasti, M Saini, A Wieland, KE Manning, M Ellis, KM Moore, SL Foster, K Floyd, ME Davis-Gardner, VV Edara, M Patel, C Steur, AK Nooka, F Green, MA Johns, F O'Brein, U Shanmugasundaram, VI Zarnitsyna, H Ahmed, LE Nyhoff, G Mantus, M Garett, S Edupuganti, M Behra, R Antia, J Wrammert, MS Suthar, MV Dhodapkar, S Ramalingam, R Ahmed	11/20/2022
Persistent intraocular Ebola virus RNA is associated with severe uveitis in a convalescent rhesus monkey. Communications biology	G Worwa, TK Cooper, S Yeh, JG Shantha, AMW Hischak, SE Klim, R Byrum, JR Kurtz, SM Anthony, NM Aiosa, D Ragland, JH Lee, MS Claire, C Davis, R Ahmed, MR Holbrook, JH Kuhn, EO Saphire, I Crozier	11/09/2022
Molecular basis of SARS-CoV-2 Omicron variant evasion from shared neutralizing antibody response. bioRxiv : the preprint server for biology	A Patel, S Kumar, L Lai, C Chakravarthy, R Valanparambil, ES Reddy, K Gottimukkala, P Bajpai, DR Raju, VV Edara, ME Davis-Gardner, S Linderman, K Dixit, P Sharma, G Mantus, N Cheedarla, HP Verkerke, F Frank, AS Neish, JD Roback, CW Davis, J Wrammert, R Ahmed, MS Suthar, A Sharma, K Murali-Krishna, A Chandele, EA Ortlund	10/24/2022
Structural insights for neutralization of Omicron variants BA.1, BA.2, BA.4, and BA.5 by a broadly neutralizing SARS-CoV-2 antibody. Science advances	S Kumar, A Patel, L Lai, C Chakravarthy, R Valanparambil, ES Reddy, K Gottimukkala, ME Davis-Gardner, VV Edara, S Linderman, K Nayak, K Dixit, P Sharma, P Bajpai, V Singh, F Frank, N Cheedarla, HP Verkerke, AS Neish, JD Roback, G Mantus, PK Goel, M Rahi, CW Davis, J Wrammert, S Godbole, AR Henry, DC Douek, MS Suthar, R Ahmed, E Ortlund, A Sharma, K Murali-Krishna, A Chandele	10/07/2022
The Quest to Eradicate HPV-Related Oropharyngeal Carcinoma: An Opportunity Not to Miss. Journal of the National Cancer Institute	CS Lalonde, Y Teng, BA Burtness, RL Ferris, R Ahmed, NF Saba	10/06/2022
TGF-β regulates the stem-like state of PD-1+ TCF-1+ virus-specific CD8 T cells during chronic infection. The Journal of experimental medicine	Y Hu, WH Hudson, HT Kissick, CB Medina, AP Baptista, C Ma, W Liao, RN Germain, SJ Turley, N Zhang, R Ahmed	10/03/2022
PD-1 combination therapy with IL-2 modifies CD8⁺ T cell exhaustion program. Nature	M Hashimoto, K Araki, MA Cardenas, P Li, RR Jadhav, HT Kissick, WH Hudson, DJ McGuire, RC Obeng, A Wieland, J Lee, DT McManus, JL Ross, SJ Im, J Lee, JX Lin, B Hu, EE West, CD Scharer, GJ Freeman, AH Sharpe, SS Ramalingam, A Pellerin, V Teichgräber, WJ Greenleaf, C Klein, JJ Goronzy, P Umaña, WJ Leonard, KA Smith, R Ahmed	10/01/2022
PD-1-cis IL-2R agonism yields better effectors from stem-like CD8⁺ T cells. Nature	L Codarri Deak, V Nicolini, M Hashimoto, M Karagianni, PC Schwalie, L Lauener, EM Varypataki, M Richard, E Bommer, J Sam, S Joller, M Perro, F Cremasco, L Kunz, E Yanguez, T Hüsser, R Schlenker, M Mariani, V Tosevski, S Herter, M Bacac, I Waldhauer, S Colombetti, X Gueripel, S Wullschleger, M Tichet, D Hanahan, HT Kissick, S Leclair, A Freimoser-Grundschober, S Seeber, V Teichgräber, R Ahmed, C Klein, P Umaña	10/01/2022
CLL-515 Antibody Responses Against SARS-CoV-2 Variants after Booster Vaccination in Patients With B Cell Non-Hodgkin Lymphoma and Chronic Lymphocytic Leukemia. Clinical lymphoma, myeloma & leukemia	A Chang, L Lai, A Akhtar, S Linderman, V Orellana-Noia, M Saini, R Valanparambil, K Blum, P Allen, M Lechowicz, J Romancik, A Ayers, C O'Leary, M Churnetski, M Kives, A Nooka, J Koff, M Dhodapkar, M Suthar, J Cohen, R Ahmed	09/27/2022
Herpes simplex virus lymphadenitis is associated with tumor reduction in a patient with chronic lymphocytic leukemia. The Journal of clinical investigation	A Chang, AM Sholukh, A Wieland, DL Jaye, M Carrington, ML Huang, H Xie, KR Jerome, P Roychoudhury, AL Greninger, JL Koff, JB Cohen, DM Koelle, L Corey, CR Flowers, R Ahmed	09/15/2022
Determinants of Neutralizing Antibody Response After SARS CoV-2 Vaccination in Patients With Myeloma. Journal of clinical oncology : official journal of the American Society of Clinical Oncology	AK Nooka, U Shanmugasundaram, N Cheedarla, H Verkerke, VV Edara, R Valanparambil, JL Kaufman, CC Hofmeister, NS Joseph, S Lonial, M Azeem, J Manalo, JM Switchenko, A Chang, SL Linderman, JD Roback, KM Dhodapkar, R Ahmed, MS Suthar, AS Neish, MV Dhodapkar	09/10/2022
Humoral Responses Against SARS-CoV-2 and Variants of Concern After mRNA Vaccines in Patients With Non-Hodgkin Lymphoma and Chronic Lymphocytic Leukemia. Journal of clinical oncology : official journal of the American Society of Clinical Oncology	A Chang, A Akhtar, SL Linderman, L Lai, VM Orellana-Noia, R Valanparambil, H Ahmed, VI Zarnitsyna, AA McCook-Veal, JM Switchenko, JL Koff, KA Blum, AA Ayers, CB O'Leary, MC Churnetski, S Sulaiman, M Kives, P Sheng, CW Davis, AK Nooka, R Antia, MV Dhodapkar, MS Suthar, JB Cohen, R Ahmed	09/10/2022
PD-1 blockade following ART interruption enhances control of pathogenic SIV in rhesus macaques. Proceedings of the National Academy of Sciences of the United States of America	V Velu, K Titanji, H Ahmed, RD Shetty, LS Chennareddi, GJ Freeman, R Ahmed, RR Amara	08/16/2022
New epigenetic regulators of T cell exhaustion. Cancer cell	H Kissick, R Ahmed	07/11/2022
Contrasting behavior between the three human monocyte subsets in dengue pathophysiology. iScience	D Maheshwari, K Saini, P Singh, M Singla, K Nayak, C Aggarwal, YM Chawla, P Bajpai, M Kaur, S Gunisetty, CS Eberhardt, R Nyodu, K Moore, MS Suthar, GR Medigeshi, E Anderson, R Lodha, SK Kabra, R Ahmed, A Chandele, K Murali-Krishna	06/17/2022
Mission, Organization, and Future Direction of the Serological Sciences Network for COVID-19 (SeroNet) Epidemiologic Cohort Studies. Open forum infectious diseases	JC Figueiredo, FR Hirsch, LH Kushi, WN Nembhard, JM Crawford, N Mantis, L Finster, NM Merin, A Merchant, KL Reckamp, GY Melmed, J Braun, D McGovern, S Parekh, DA Corley, N Zohoori, BC Amick, R Du, PK Gregersen, B Diamond, E Taioli, C Sariol, A Espino, D Weiskopf, A Gifoni, J Brien, W Hanege, M Lipsitch, DA Zidar, A Scheck McAlearney, A Wajnberg, J LaBaer, E Yvonne Lewis, RA Binder, AM Moormann, C Forconi, S Forrester, J Batista, J Schieffelin, D Kim, G Biancon, J VanOudenhove, S Halene, R Fan, DH Barouch, G Alter, S Pinninti, SB Boppana, SK Pati, M Latting, AH Karaba, J Roback, R Sekaly, A Neish, AM Brincks, DA Granger, AB Karger, B Thyagarajan, SN Thomas, SL Klein, AL Cox, T Lucas, D Furr-Holden, K Key, N Jones, J Wrammerr, M Suthar, S Yu Wong, NM Bowman, V Simon, LD Richardson, R McBride, F Krammer, M Rana, J Kennedy, K Boehme, C Forrest, SW Granger, CD Heaney, M Knight Lapinski, S Wallet, RS Baric, L Schifanella, M Lopez, S Fernández, E Kenah, AR Panchal, WJ Britt, I Sanz, M Dhodapkar, R Ahmed, LA Bartelt, AJ Markmann, JT Lin, RS Hagan, MC Wolfgang, J Skarbinski	06/01/2022
Distinct phenotypic states and spatial distribution of CD8⁺ T cell clonotypes in human brain metastases. Cell reports. Medicine	LJ Sudmeier, KB Hoang, EK Nduom, A Wieland, SG Neill, MJ Schniederjan, SS Ramalingam, JJ Olson, R Ahmed, WH Hudson	05/17/2022
Persistence of Virus-Specific Antibody after Depletion of Memory B Cells. Journal of virology	WA Langley, A Wieland, H Ahmed, MAU Rasheed, CW Davis, J Sewatanon, SN Mueller, MJ Shlomchik, VI Zarnitsyna, R Antia, R Ahmed	05/11/2022
Pre-existing SARS-CoV-2 immunity influences potency, breadth, and durability of the humoral response to SARS-CoV-2 vaccination. Cell reports. Medicine	G Mantus, LE Nyhoff, VV Edara, VI Zarnitsyna, CR Ciric, MW Flowers, C Norwood, M Ellis, L Hussaini, KE Manning, K Stephens, EJ Anderson, R Ahmed, MS Suthar, J Wrammert	04/19/2022
Asymmetric and non-stoichiometric glycoprotein recognition by two distinct antibodies results in broad protection against ebolaviruses. Cell	JC Milligan, CW Davis, X Yu, PA Ilinykh, K Huang, PJ Halfmann, RW Cross, V Borisevich, KN Agans, JB Geisbert, C Chennareddy, AJ Goff, AE Piper, S Hui, KCL Shaffer, T Buck, ML Heinrich, LM Branco, I Crozier, MR Holbrook, JH Kuhn, Y Kawaoka, PJ Glass, A Bukreyev, TW Geisbert, G Worwa, R Ahmed, EO Saphire	03/17/2022
In vivo mRNA delivery to virus-specific T cells by light-induced ligand exchange of MHC class I antigen-presenting nanoparticles. Science advances	FY Su, QH Zhao, SN Dahotre, L Gamboa, SS Bawage, AD Silva Trenkle, A Zamat, H Phuengkham, R Ahmed, PJ Santangelo, GA Kwong	02/25/2022
Induction of thymic atrophy and loss of thymic output by type-I interferons during chronic viral infection. Virology	T Démoulins, ML Baron, D Gauchat, N Kettaf, SJ Reed, T Charpentier, U Kalinke, A Lamarre, R Ahmed, RP Sékaly, S Sarkar, V Kalia	02/01/2022
Antibody response to SARS-CoV-2 mRNA vaccine in lung cancer patients: Reactivity to vaccine antigen and variants of concern. medRxiv : the preprint server for health sciences	R Valanparambil, J Carlisle, S Linderman, A Akthar, RL Millett, L Lai, A Chang, A McCook, J Switchenko, T Nasti, M Saini, AW Andreas Wieland, K Manning, M Ellis, K Moore, S Foster, K Floyd, M Davis-Gardner, V Viswanadh Edara, M Patel, C Steur, A Nooka, F Green, M Johns, F O Brein, U Shanmugasundaram, V Zarnitsyna, H Ahmed, L Nyhoff, G Mantus, M Garett, S Edupuganti, M Behra, R Antia, J Wrammert, M Suthar, M Dhodapkar, S Ramalingam, R Ahmed	01/23/2022
Evolving Views of Long Noncoding RNAs and Epigenomic Control of Lymphocyte State and Memory. Cold Spring Harbor perspectives in biology	TA Morrison, WH Hudson, DA Chisolm, Y Kanno, HY Shih, R Ahmed, J Henao-Mejia, M Hafner, JJ O'Shea	01/04/2022
COVID-19 and the eye: Systemic and laboratory risk factors for retinopathy and detection of tear film SARS-CoV-2 RNA with a triplex RT-PCR assay. PloS one	JG Shantha, T Fashina, V Stittleburg, C Randleman, L Ward, M Regueiro, D Krakow, SL Linderman, C Drews-Botsch, R Ahmed, J Waggoner, S Yeh	01/01/2022
Characteristics of Ebola Virus Disease Survivor Blood and Semen in Liberia: Serology and Reverse Transcription Polymerase Chain Reaction (RT-PCR). Clinical infectious diseases : an official publication of the Infectious Diseases Society of America	A Kofman, S Linderman, K Su, LJ Purpura, E Ervin, S Brown, M Morales-Betoulle, J Graziano, DL Cannon, JD Klena, R Desamu-Thorpe, J Fankhauser, R Orone, S Moses, U Glaybo, M Massaquoi, T Nyenswah, ST Nichol, J Kollie, A Kiawu, E Freeman, G Giah, H Tony, M Faikai, M Jawara, K Kamara, S Kamara, B Flowers, K Mohammed, D Chiriboga, DE Williams, SH Hinrichs, R Ahmed, B Vonhm, PE Rollin, MJ Choi	12/06/2021
Whole-lung low-dose radiation therapy (LD-RT) for non-intubated oxygen-dependent patients with COVID-19-related pneumonia receiving dexamethasone and/or remdesevir. Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology	CB Hess, TY Eng, TH Nasti, VR Dhere, TJ Kleber, JM Switchenko, BD Weinberg, N Rouphael, S Tian, S Rudra, LS Taverna, AP Daisson, R Ahmed, MK Khan	12/01/2021
Immunophenotyping and Transcriptional Profiling of Human Plasmablasts in Dengue. Journal of virology	C Aggarwal, K Saini, ES Reddy, M Singla, K Nayak, YM Chawla, D Maheshwari, P Singh, P Sharma, P Bhatnagar, S Kumar, K Gottimukkala, H Panda, S Gunisetty, CW Davis, HT Kissick, SK Kabra, R Lodha, GR Medigeshi, R Ahmed, K Murali-Krishna, A Chandele	11/09/2021
Influenza Immunization in the Context of Preexisting Immunity. Cold Spring Harbor perspectives in medicine	SL Linderman, AH Ellebedy, C Davis, CS Eberhardt, R Antia, R Ahmed, VI Zarnitsyna	11/01/2021
B cells and cancer. Cancer cell	V Engelhard, JR Conejo-Garcia, R Ahmed, BH Nelson, K Willard-Gallo, TC Bruno, WH Fridman	10/11/2021
Dynamics and turnover of memory CD8 T cell responses following yellow fever vaccination. PLoS computational biology	VI Zarnitsyna, RS Akondy, H Ahmed, DJ McGuire, VG Zarnitsyn, M Moore, PLF Johnson, R Ahmed, KW Li, MK Hellerstein, R Antia	10/01/2021
PD-1 blockade and vaccination provide therapeutic benefit against SIV by inducing broad and functional CD8⁺ T cells in lymphoid tissue. Science immunology	SA Rahman, B Yagnik, AP Bally, KN Morrow, S Wang, TH Vanderford, GJ Freeman, R Ahmed, RR Amara	09/10/2021
Defining HPV-specific B cell responses in patients with head and neck cancer. Nature	A Wieland, MR Patel, MA Cardenas, CS Eberhardt, WH Hudson, RC Obeng, CC Griffith, X Wang, ZG Chen, HT Kissick, NF Saba, R Ahmed	09/01/2021
Functional HPV-specific PD-1⁺ stem-like CD8 T cells in head and neck cancer. Nature	CS Eberhardt, HT Kissick, MR Patel, MA Cardenas, N Prokhnevska, RC Obeng, TH Nasti, CC Griffith, SJ Im, X Wang, DM Shin, M Carrington, ZG Chen, J Sidney, A Sette, NF Saba, A Wieland, R Ahmed	09/01/2021
Longitudinal analysis shows durable and broad immune memory after SARS-CoV-2 infection with persisting antibody responses and memory B and T cells. Cell reports. Medicine	KW Cohen, SL Linderman, Z Moodie, J Czartoski, L Lai, G Mantus, C Norwood, LE Nyhoff, VV Edara, K Floyd, SC De Rosa, H Ahmed, R Whaley, SN Patel, B Prigmore, MP Lemos, CW Davis, S Furth, JB O'Keefe, MP Gharpure, S Gunisetty, K Stephens, R Antia, VI Zarnitsyna, DS Stephens, S Edupuganti, N Rouphael, EJ Anderson, AK Mehta, J Wrammert, MS Suthar, R Ahmed, MJ McElrath	07/20/2021
Immunological lessons from CD28 deficiency in humans. Cell	A Wieland, R Ahmed	07/08/2021
Longitudinal analysis shows durable and broad immune memory after SARS-CoV-2 infection with persisting antibody responses and memory B and T cells. medRxiv : the preprint server for health sciences	KW Cohen, SL Linderman, Z Moodie, J Czartoski, L Lai, G Mantus, C Norwood, LE Nyhoff, VV Edara, K Floyd, SC De Rosa, H Ahmed, R Whaley, SN Patel, B Prigmore, MP Lemos, CW Davis, S Furth, J O'Keefe, MP Gharpure, S Gunisetty, KA Stephens, R Antia, VI Zarnitsyna, DS Stephens, S Edupuganti, N Rouphael, EJ Anderson, AK Mehta, J Wrammert, MS Suthar, R Ahmed, MJ McElrath	06/18/2021
Evaluation of Cellular and Serological Responses to Acute SARS-CoV-2 Infection Demonstrates the Functional Importance of the Receptor-Binding Domain. Journal of immunology (Baltimore, Md. : 1950)	G Mantus, LE Nyhoff, RC Kauffman, VV Edara, L Lai, K Floyd, PY Shi, VD Menachery, S Edupuganti, EM Scherer, A Kay, N McNair, EJ Anderson, N Rouphael, R Ahmed, MS Suthar, J Wrammert	06/01/2021
Characterization of neutralizing versus binding antibodies and memory B cells in COVID-19 recovered individuals from India. Virology	K Nayak, K Gottimukkala, S Kumar, ES Reddy, VV Edara, R Kauffman, K Floyd, G Mantus, D Savargaonkar, PK Goel, S Arora, M Rahi, CW Davis, S Linderman, J Wrammert, MS Suthar, R Ahmed, A Sharma, K Murali-Krishna, A Chandele	06/01/2021
Retinopathy and Systemic Disease Morbidity in Severe COVID-19. Ocular immunology and inflammation	JG Shantha, SC Auld, C Anthony, L Ward, MW Adelman, CL Maier, KW Price, JT Jacob, T Fashina, C Randleman, LT Xu, J Barnett, O Sadan, PA Kandiah, JB Varkey, CS Kraft, N Rouphael, S Linderman, R Ahmed, C Drews-Botsch, JJ Waggoner, M Weinmann, DJ Murphy, S Yeh	05/19/2021
PD-1 suppresses TCR-CD8 cooperativity during T-cell antigen recognition. Nature communications	K Li, Z Yuan, J Lyu, E Ahn, SJ Davis, R Ahmed, C Zhu	05/12/2021
Neutralizing Antibodies Against SARS-CoV-2 Variants After Infection and Vaccination. JAMA	VV Edara, WH Hudson, X Xie, R Ahmed, MS Suthar	05/11/2021
Infection- and vaccine-induced antibody binding and neutralization of the B.1.351 SARS-CoV-2 variant. Cell host & microbe	VV Edara, C Norwood, K Floyd, L Lai, ME Davis-Gardner, WH Hudson, G Mantus, LE Nyhoff, MW Adelman, R Fineman, S Patel, R Byram, DN Gomes, G Michael, H Abdullahi, N Beydoun, B Panganiban, N McNair, K Hellmeister, J Pitts, J Winters, J Kleinhenz, J Usher, JB O'Keefe, A Piantadosi, JJ Waggoner, A Babiker, DS Stephens, EJ Anderson, S Edupuganti, N Rouphael, R Ahmed, J Wrammert, MS Suthar	04/14/2021
Auto-antibodies to type I IFNs can underlie adverse reactions to yellow fever live attenuated vaccine. The Journal of experimental medicine	P Bastard, E Michailidis, HH Hoffmann, M Chbihi, T Le Voyer, J Rosain, Q Philippot, Y Seeleuthner, A Gervais, M Materna, PMN de Oliveira, MLS Maia, AP Dinis Ano Bom, T Azamor, D Araújo da Conceição, E Goudouris, A Homma, G Slesak, J Schäfer, B Pulendran, JD Miller, R Huits, R Yang, LB Rosen, L Bizien, L Lorenzo, M Chrabieh, LV Erazo, F Rozenberg, MM Jeljeli, V Béziat, SM Holland, A Cobat, LD Notarangelo, HC Su, R Ahmed, A Puel, SY Zhang, L Abel, SJ Seligman, Q Zhang, MR MacDonald, E Jouanguy, CM Rice, JL Casanova	04/05/2021
Immunomodulatory Low-Dose Whole-Lung Radiation for Patients with Coronavirus Disease 2019-Related Pneumonia. International journal of radiation oncology, biology, physics	CB Hess, TH Nasti, VR Dhere, TJ Kleber, JM Switchenko, ZS Buchwald, WA Stokes, BD Weinberg, N Rouphael, JP Steinberg, KD Godette, DJ Murphy, R Ahmed, WJ Curran, MK Khan	03/15/2021
Reduced binding and neutralization of infection- and vaccine-induced antibodies to the B.1.351 (South African) SARS-CoV-2 variant. bioRxiv : the preprint server for biology	VV Edara, C Norwood, K Floyd, L Lai, ME Davis-Gardner, WH Hudson, G Mantus, LE Nyhoff, MW Adelman, R Fineman, S Patel, R Byram, DN Gomes, G Michael, H Abdullahi, N Beydoun, B Panganiban, N McNair, K Hellmeister, J Pitts, J Winters, J Kleinhenz, J Usher, JB O'Keefe, A Piantadosi, JJ Waggoner, A Babiker, DS Stephens, EJ Anderson, S Edupuganti, N Rouphael, R Ahmed, J Wrammert, MS Suthar	02/22/2021
Infection and mRNA-1273 vaccine antibodies neutralize SARS-CoV-2 UK variant. medRxiv : the preprint server for health sciences	VV Edara, K Floyd, L Lai, M Gardner, W Hudson, A Piantadosi, JJ Waggoner, A Babiker, R Ahmed, X Xie, K Lokugamage, V Menachery, PY Shi, MS Suthar	02/05/2021
Viral Immunity and Vaccines in Hematologic Malignancies: Implications for COVID-19. Blood cancer discovery	MV Dhodapkar, KM Dhodapkar, R Ahmed	01/01/2021
Heat Shock Protein-90 Inhibition Alters Activation of Pancreatic Stellate Cells and Enhances the Efficacy of PD-1 Blockade in Pancreatic Cancer. Molecular cancer therapeutics	MB Ware, MY Zaidi, AN Ruggieri, BM Olson, H Komar, MR Farren, GP Nagaraju, C Zhang, Z Chen, JM Sarmiento, R Ahmed, SK Maithel, BF El-Rayes, GB Lesinski	01/01/2021
Low-dose whole-lung radiation for COVID-19 pneumonia: Planned day 7 interim analysis of a registered clinical trial. Cancer	CB Hess, ZS Buchwald, W Stokes, TH Nasti, JM Switchenko, BD Weinberg, JP Steinberg, KD Godette, D Murphy, R Ahmed, WJ Curran, MK Khan	12/01/2020
Immunomodulatory Low-Dose Whole-Lung Radiation for Patients with COVID-19-Related Pneumonia. International journal of radiation oncology, biology, physics	CB Hess, ZS Buchwald, WA Stokes, T Nasti, J Switchenko, BD Weinberg, N Rouphael, JP Steinberg, KD Godette, DJ Murphy, R Ahmed, WJ Curran, MK Khan	12/01/2020
Influenza vaccine-induced human bone marrow plasma cells decline within a year after vaccination. Science (New York, N.Y.)	CW Davis, KJL Jackson, MM McCausland, J Darce, C Chang, SL Linderman, C Chennareddy, R Gerkin, SJ Brown, J Wrammert, AK Mehta, WC Cheung, SD Boyd, EK Waller, R Ahmed	10/09/2020
Tumor-draining lymph node is important for a robust abscopal effect stimulated by radiotherapy. Journal for immunotherapy of cancer	ZS Buchwald, TH Nasti, J Lee, CS Eberhardt, A Wieland, SJ Im, D Lawson, W Curran, R Ahmed, MK Khan	10/01/2020
T Cell Receptor Diversity and Lineage Relationship between Virus-Specific CD8 T Cell Subsets during Chronic Lymphocytic Choriomeningitis Virus Infection. Journal of virology	YM Chang, A Wieland, ZR Li, SJ Im, DJ McGuire, HT Kissick, R Antia, R Ahmed	09/29/2020
Exosome-Containing Preparations From Postirradiated Mouse Melanoma Cells Delay Melanoma Growth In Vivo by a Natural Killer Cell-Dependent Mechanism. International journal of radiation oncology, biology, physics	KK Jella, TH Nasti, Z Li, DH Lawson, JM Switchenko, R Ahmed, WS Dynan, MK Khan	09/01/2020
Adjuvanted H5N1 influenza vaccine enhances both cross-reactive memory B cell and strain-specific naive B cell responses in humans. Proceedings of the National Academy of Sciences of the United States of America	AH Ellebedy, R Nachbagauer, KJL Jackson, YN Dai, J Han, WB Alsoussi, CW Davis, D Stadlbauer, N Rouphael, V Chromikova, M McCausland, CY Chang, M Cortese, M Bower, C Chennareddy, AJ Schmitz, VI Zarnitsyna, L Lai, A Rajabhathor, C Kazemian, R Antia, MJ Mulligan, AB Ward, DH Fremont, SD Boyd, B Pulendran, F Krammer, R Ahmed	07/28/2020
Rapid Generation of Neutralizing Antibody Responses in COVID-19 Patients. Cell reports. Medicine	MS Suthar, MG Zimmerman, RC Kauffman, G Mantus, SL Linderman, WH Hudson, A Vanderheiden, L Nyhoff, CW Davis, O Adekunle, M Affer, M Sherman, S Reynolds, HP Verkerke, DN Alter, J Guarner, J Bryksin, MC Horwath, CM Arthur, N Saakadze, GH Smith, S Edupuganti, EM Scherer, K Hellmeister, A Cheng, JA Morales, AS Neish, SR Stowell, F Frank, E Ortlund, EJ Anderson, VD Menachery, N Rouphael, AK Mehta, DS Stephens, R Ahmed, JD Roback, J Wrammert	06/23/2020
3M-052, a synthetic TLR-7/8 agonist, induces durable HIV-1 envelope-specific plasma cells and humoral immunity in nonhuman primates. Science immunology	SP Kasturi, MAU Rasheed, C Havenar-Daughton, M Pham, T Legere, ZJ Sher, Y Kovalenkov, S Gumber, JY Huang, R Gottardo, W Fulp, A Sato, S Sawant, S Stanfield-Oakley, N Yates, C LaBranche, SM Alam, G Tomaras, G Ferrari, D Montefiori, J Wrammert, F Villinger, M Tomai, J Vasilakos, CB Fox, SG Reed, BF Haynes, S Crotty, R Ahmed, B Pulendran	06/19/2020
Persistence of Varicella-Zoster Virus-Specific Plasma Cells in Adult Human Bone Marrow following Childhood Vaccination. Journal of virology	CS Eberhardt, A Wieland, TH Nasti, A Grifoni, E Wilson, DS Schmid, B Pulendran, A Sette, EK Waller, N Rouphael, R Ahmed	06/16/2020
Rapid generation of neutralizing antibody responses in COVID-19 patients. medRxiv : the preprint server for health sciences	MS Suthar, M Zimmerman, R Kauffman, G Mantus, S Linderman, A Vanderheiden, L Nyhoff, C Davis, S Adekunle, M Affer, M Sherman, S Reynolds, H Verkerke, DN Alter, J Guarner, J Bryksin, M Horwath, C Arthur, N Saakadze, GH Smith, S Edupuganti, EM Scherer, K Hellmeister, A Cheng, JA Morales, AS Neish, SR Stowell, F Frank, E Ortlund, E Anderson, V Menachery, N Rouphael, A Metha, DS Stephens, R Ahmed, J Roback, J Wrammert	05/08/2020
PD-1+ stemlike CD8 T cells are resident in lymphoid tissues during persistent LCMV infection. Proceedings of the National Academy of Sciences of the United States of America	SJ Im, BT Konieczny, WH Hudson, D Masopust, R Ahmed	02/25/2020
Minimal immune response to booster vaccination against Yellow Fever associated with pre-existing antibodies. Vaccine	A Bovay, S Nassiri, H Maby-El Hajjami, P Marcos Mondéjar, RS Akondy, R Ahmed, B Lawson, DE Speiser, SA Fuertes Marraco	02/24/2020
Immune checkpoint modulation enhances HIV-1 antibody induction. Nature communications	T Bradley, M Kuraoka, CH Yeh, M Tian, H Chen, DW Cain, X Chen, C Cheng, AH Ellebedy, R Parks, M Barr, LL Sutherland, RM Scearce, CM Bowman, H Bouton-Verville, S Santra, K Wiehe, MG Lewis, A Ogbe, P Borrow, D Montefiori, M Bonsignori, M Anthony Moody, L Verkoczy, KO Saunders, R Ahmed, JR Mascola, G Kelsoe, FW Alt, BF Haynes	02/19/2020
Editorial: HIV and Cancer Immunotherapy: Similar Challenges and Converging Approaches. Frontiers in immunology	M Paiardini, K Dhodapkar, J Harper, SG Deeks, R Ahmed	01/01/2020
Harnessing Activin A Adjuvanticity to Promote Antibody Responses to BG505 HIV Envelope Trimers. Frontiers in immunology	DG Carnathan, K Kaushik, AH Ellebedy, CA Enemuo, EH Gebru, P Dhadvai, MAU Rasheed, MG Pauthner, G Ozorowski, R Ahmed, DR Burton, AB Ward, G Silvestri, S Crotty, M Locci	01/01/2020
Proliferating Transitory T Cells with an Effector-like Transcriptional Signature Emerge from PD-1⁺ Stem-like CD8⁺ T Cells during Chronic Infection. Immunity	WH Hudson, J Gensheimer, M Hashimoto, A Wieland, RM Valanparambil, P Li, JX Lin, BT Konieczny, SJ Im, GJ Freeman, WJ Leonard, HT Kissick, R Ahmed	12/17/2019
Regulation of T and B cell responses to chronic antigenic stimulation during Infection, autoimmunity and transplantation. Immunological reviews	R Ahmed, ML Ford, I Sanz	11/01/2019
The Magnitude of IFN-γ Responses Is Fine-Tuned by DNA Architecture and the Non-coding Transcript of Ifng-as1. Molecular cell	F Petermann, A Pękowska, CA Johnson, D Jankovic, HY Shih, K Jiang, WH Hudson, SR Brooks, HW Sun, AV Villarino, C Yao, K Singleton, RS Akondy, Y Kanno, A Sher, R Casellas, R Ahmed, JJ O'Shea	09/19/2019
Decreased humoral immunity to mumps in young adults immunized with MMR vaccine in childhood. Proceedings of the National Academy of Sciences of the United States of America	MAU Rasheed, CJ Hickman, M McGrew, SB Sowers, S Mercader, A Hopkins, V Grimes, T Yu, J Wrammert, MJ Mulligan, WJ Bellini, PA Rota, WA Orenstein, R Ahmed, S Edupuganti	09/17/2019
Interleukin-6/STAT3 Signaling is Prominent and Associated with Reduced Overall Survival in p16 Negative Oropharyngeal Squamous Cell Carcinoma. Head and neck pathology	GB Lesinski, S Nannapaneni, CC Griffith, M Patel, W Chen, Z Chen, R Ahmed, A Wieland, DM Shin, ZG Chen, NF Saba	09/01/2019
Understanding the immunology of the Zostavax shingles vaccine. Current opinion in immunology	NL Sullivan, CS Eberhardt, A Wieland, KA Vora, B Pulendran, R Ahmed	08/01/2019
Epigenetic signature of PD-1+ TCF1+ CD8 T cells that act as resource cells during chronic viral infection and respond to PD-1 blockade. Proceedings of the National Academy of Sciences of the United States of America	RR Jadhav, SJ Im, B Hu, M Hashimoto, P Li, JX Lin, WJ Leonard, WJ Greenleaf, R Ahmed, JJ Goronzy	07/09/2019
Characterization of Virus-specific Immune Response During Varicella Zoster Virus Encephalitis in a Young Adult. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America	NL Sullivan, CS Eberhardt, A Wieland, RS Akondy, J Yi, AK McElroy, R Ahmed	07/02/2019
Dependence of CD8 T Cell Response upon Antigen Load During Primary Infection : Analysis of Data from Yellow Fever Vaccination. Bulletin of mathematical biology	JR Moore, H Ahmed, D McGuire, R Akondy, R Ahmed, R Antia	07/01/2019
Analysis of dengue specific memory B cells, neutralizing antibodies and binding antibodies in healthy adults from India. International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases	S Gunisetty, K Nayak, R Chandra Rai, Y Chawla, ES Reddy, C Aggarwal, D Maheshwari, H Panda, NA Ansari, P Singh, M Kaur, K Dixit, P Sharma, P Bhatnagar, L Priyamvada, SK Bhaumik, SF Ahamed, R Vivek, P Ray, A Shet, P Coshic, R Lodha, SK Kabra, D Afroze, A Yousuf, R Ahmed, K Murali-Krishna, A Chandele	07/01/2019
Longitudinal Analysis of the Human B Cell Response to Ebola Virus Infection. Cell	CW Davis, KJL Jackson, AK McElroy, P Halfmann, J Huang, C Chennareddy, AE Piper, Y Leung, CG Albariño, I Crozier, AH Ellebedy, J Sidney, A Sette, T Yu, SCA Nielsen, AJ Goff, CF Spiropoulou, EO Saphire, G Cavet, Y Kawaoka, AK Mehta, PJ Glass, SD Boyd, R Ahmed	05/30/2019
Broad Hemagglutinin-Specific Memory B Cell Expansion by Seasonal Influenza Virus Infection Reflects Early-Life Imprinting and Adaptation to the Infecting Virus. Journal of virology	BL Tesini, P Kanagaiah, J Wang, M Hahn, JL Halliley, FA Chaves, PQT Nguyen, A Nogales, ML DeDiego, CS Anderson, AH Ellebedy, S Strohmeier, F Krammer, H Yang, S Bandyopadhyay, R Ahmed, JJ Treanor, L Martinez-Sobrido, H Golding, S Khurana, MS Zand, DJ Topham, MY Sangster	04/15/2019
Antigenic Drift of the Influenza A(H1N1)pdm09 Virus Neuraminidase Results in Reduced Effectiveness of A/California/7/2009 (H1N1pdm09)-Specific Antibodies. mBio	J Gao, L Couzens, DF Burke, H Wan, P Wilson, MJ Memoli, X Xu, R Harvey, J Wrammert, R Ahmed, JK Taubenberger, DJ Smith, RAM Fouchier, MC Eichelberger	04/09/2019
Influenza Vaccination Documentation Rates During the First Year After Diagnosis of Diffuse Large B Cell Lymphoma. Clinical lymphoma, myeloma & leukemia	A Chang, JB Payne, PB Allen, JL Koff, R Ahmed, CR Flowers, RA Bednarczyk	04/01/2019
Kinetics of antibody response to influenza vaccination in renal transplant recipients. Transplant immunology	S Gangappa, J Wrammert, D Wang, ZN Li, JS Liepkalns, W Cao, J Chen, MZ Levine, J Stevens, S Sambhara, B Begley, A Mehta, TC Pearson, R Ahmed, CP Larsen	04/01/2019
Influenza Virus Vaccination Elicits Poorly Adapted B Cell Responses in Elderly Individuals. Cell host & microbe	C Henry, NY Zheng, M Huang, A Cabanov, KT Rojas, K Kaur, SF Andrews, AE Palm, YQ Chen, Y Li, K Hoskova, HA Utset, MC Vieira, J Wrammert, R Ahmed, J Holden-Wiltse, DJ Topham, JJ Treanor, HC Ertl, KE Schmader, S Cobey, F Krammer, SE Hensley, H Greenberg, XS He, PC Wilson	03/13/2019
Expression of novel long noncoding RNAs defines virus-specific effector and memory CD8⁺ T cells. Nature communications	WH Hudson, N Prokhnevska, J Gensheimer, R Akondy, DJ McGuire, R Ahmed, HT Kissick	01/14/2019
Cytokine-Mediated Regulation of CD8 T-Cell Responses During Acute and Chronic Viral Infection. Cold Spring Harbor perspectives in biology	M Hashimoto, SJ Im, K Araki, R Ahmed	01/02/2019
Repurposing Food and Drug Administration-Approved Drugs to Promote Antitumor Immunity. Cancer journal (Sudbury, Mass.)	VV Sukhatme, SS Ramalingam, R Ahmed, VP Sukhatme	01/01/2019
Fc Receptors in Antimicrobial Protection. Current topics in microbiology and immunology	A Wieland, R Ahmed	01/01/2019
Activation of miR-21-Regulated Pathways in Immune Aging Selects against Signatures Characteristic of Memory T Cells. Cell reports	C Kim, B Hu, RR Jadhav, J Jin, H Zhang, MM Cavanagh, RS Akondy, R Ahmed, CM Weyand, JJ Goronzy	11/20/2018
In Vivo Delivery of Synthetic Human DNA-Encoded Monoclonal Antibodies Protect against Ebolavirus Infection in a Mouse Model. Cell reports	A Patel, DH Park, CW Davis, TRF Smith, A Leung, K Tierney, A Bryan, E Davidson, X Yu, T Racine, C Reed, ME Gorman, MC Wise, STC Elliott, R Esquivel, J Yan, J Chen, K Muthumani, BJ Doranz, EO Saphire, JE Crowe, KE Broderick, GP Kobinger, S He, X Qiu, D Kobasa, L Humeau, NY Sardesai, R Ahmed, DB Weiner	11/13/2018
T cell receptor sequencing of activated CD8 T cells in the blood identifies tumor-infiltrating clones that expand after PD-1 therapy and radiation in a melanoma patient. Cancer immunology, immunotherapy : CII	A Wieland, AO Kamphorst, NV Adsay, JJ Masor, J Sarmiento, TH Nasti, S Darko, DC Douek, Y Xue, WJ Curran, DH Lawson, R Ahmed	11/01/2018
Enhancing FcγR-mediated antibody effector function during persistent viral infection. Science immunology	A Wieland, AO Kamphorst, RM Valanparambil, JH Han, X Xu, BP Choudhury, R Ahmed	09/21/2018
Combination anti-PD-1 and antiretroviral therapy provides therapeutic benefit against SIV. JCI insight	GH Mylvaganam, LS Chea, GK Tharp, S Hicks, V Velu, SS Iyer, C Deleage, JD Estes, SE Bosinger, GJ Freeman, R Ahmed, RR Amara	09/20/2018
Myocarditis With Radiotherapy and Immunotherapy in Multiple Myeloma. Journal of oncology practice	A Chang, TH Nasti, MK Khan, S Parashar, JL Kaufman, LH Boise, S Lonial, R Ahmed, AK Nooka	09/01/2018
Broadly Reactive Human Monoclonal Antibodies Elicited following Pandemic H1N1 Influenza Virus Exposure Protect Mice against Highly Pathogenic H5N1 Challenge. Journal of virology	R Nachbagauer, D Shore, H Yang, SK Johnson, JD Gabbard, SM Tompkins, J Wrammert, PC Wilson, J Stevens, R Ahmed, F Krammer, AH Ellebedy	08/15/2018
Systematic Analysis of Monoclonal Antibodies against Ebola Virus GP Defines Features that Contribute to Protection. Cell	EO Saphire, SL Schendel, ML Fusco, K Gangavarapu, BM Gunn, AZ Wec, PJ Halfmann, JM Brannan, AS Herbert, X Qiu, K Wagh, S He, EE Giorgi, J Theiler, KBJ Pommert, TB Krause, HL Turner, CD Murin, J Pallesen, E Davidson, R Ahmed, MJ Aman, A Bukreyev, DR Burton, JE Crowe, CW Davis, G Georgiou, F Krammer, CA Kyratsous, JR Lai, C Nykiforuk, MH Pauly, P Rijal, A Takada, AR Townsend, V Volchkov, LM Walker, CI Wang, L Zeitlin, BJ Doranz, AB Ward, B Korber, GP Kobinger, KG Andersen, Y Kawaoka, G Alter, K Chandran, JM Dye	08/09/2018
Breadth and Functionality of Varicella-Zoster Virus Glycoprotein-Specific Antibodies Identified after Zostavax Vaccination in Humans. Journal of virology	NL Sullivan, MA Reuter-Monslow, J Sei, E Durr, CW Davis, C Chang, M McCausland, A Wieland, D Krah, N Rouphael, AK Mehta, MJ Mulligan, B Pulendran, R Ahmed, KA Vora	07/15/2018
Lymphoid tissue fibrosis is associated with impaired vaccine responses. The Journal of clinical investigation	C Kityo, KN Makamdop, M Rothenberger, JG Chipman, T Hoskuldsson, GJ Beilman, B Grzywacz, P Mugyenyi, F Ssali, RS Akondy, J Anderson, TE Schmidt, T Reimann, SP Callisto, J Schoephoerster, J Schuster, P Muloma, P Ssengendo, E Moysi, C Petrovas, R Lanciotti, L Zhang, MT Arévalo, B Rodriguez, TM Ross, L Trautmann, RP Sekaly, MM Lederman, RA Koup, R Ahmed, C Reilly, DC Douek, TW Schacker	07/02/2018
Role of PD-1 during effector CD8 T cell differentiation. Proceedings of the National Academy of Sciences of the United States of America	E Ahn, K Araki, M Hashimoto, W Li, JL Riley, J Cheung, AH Sharpe, GJ Freeman, BA Irving, R Ahmed	05/01/2018
Influenza Infection in Humans Induces Broadly Cross-Reactive and Protective Neuraminidase-Reactive Antibodies. Cell	YQ Chen, TJ Wohlbold, NY Zheng, M Huang, Y Huang, KE Neu, J Lee, H Wan, KT Rojas, E Kirkpatrick, C Henry, AE Palm, CT Stamper, LY Lan, DJ Topham, J Treanor, J Wrammert, R Ahmed, MC Eichelberger, G Georgiou, F Krammer, PC Wilson	04/05/2018
A Direct Comparison of in Vitro and in Vivo Nucleic Acid Delivery Mediated by Hundreds of Nanoparticles Reveals a Weak Correlation. Nano letters	K Paunovska, CD Sago, CM Monaco, WH Hudson, MG Castro, TG Rudoltz, S Kalathoor, DA Vanover, PJ Santangelo, R Ahmed, AV Bryksin, JE Dahlman	03/14/2018
CD8 T Cell Exhaustion in Chronic Infection and Cancer: Opportunities for Interventions. Annual review of medicine	M Hashimoto, AO Kamphorst, SJ Im, HT Kissick, RN Pillai, SS Ramalingam, K Araki, R Ahmed	01/29/2018
Comparison of the toxicity profile of PD-1 versus PD-L1 inhibitors in non-small cell lung cancer: A systematic analysis of the literature. Cancer	RN Pillai, M Behera, TK Owonikoko, AO Kamphorst, S Pakkala, CP Belani, FR Khuri, R Ahmed, SS Ramalingam	01/15/2018
What Controls the Acute Viral Infection Following Yellow Fever Vaccination? Bulletin of mathematical biology	J Moore, H Ahmed, J Jia, R Akondy, R Ahmed, R Antia	01/01/2018
A tetravalent virus-like particle vaccine designed to display domain III of dengue envelope proteins induces multi-serotype neutralizing antibodies in mice and macaques which confer protection against antibody dependent enhancement in AG129 mice. PLoS neglected tropical diseases	V Ramasamy, U Arora, R Shukla, A Poddar, RK Shanmugam, LJ White, MM Mattocks, R Raut, A Perween, P Tyagi, AM de Silva, SK Bhaumik, MK Kaja, F Villinger, R Ahmed, RE Johnston, S Swaminathan, N Khanna	01/01/2018
Effector CD8 T cells dedifferentiate into long-lived memory cells. Nature	B Youngblood, JS Hale, HT Kissick, E Ahn, X Xu, A Wieland, K Araki, EE West, HE Ghoneim, Y Fan, P Dogra, CW Davis, BT Konieczny, R Antia, X Cheng, R Ahmed	12/21/2017
Origin and differentiation of human memory CD8 T cells after vaccination. Nature	RS Akondy, M Fitch, S Edupuganti, S Yang, HT Kissick, KW Li, BA Youngblood, HA Abdelsamed, DJ McGuire, KW Cohen, G Alexe, S Nagar, MM McCausland, S Gupta, P Tata, WN Haining, MJ McElrath, D Zhang, B Hu, WJ Greenleaf, JJ Goronzy, MJ Mulligan, M Hellerstein, R Ahmed	12/21/2017
Humoral Immune Responses Against Zika Virus Infection and the Importance of Preexisting Flavivirus Immunity. The Journal of infectious diseases	L Priyamvada, MS Suthar, R Ahmed, J Wrammert	12/16/2017
Advancing dengue vaccine development. Science (New York, N.Y.)	MB Feinberg, R Ahmed	11/17/2017
Translation is actively regulated during the differentiation of CD8⁺ effector T cells. Nature immunology	K Araki, M Morita, AG Bederman, BT Konieczny, HT Kissick, N Sonenberg, R Ahmed	09/01/2017
In Vivo Imaging of Influenza Virus Infection in Immunized Mice. mBio	R Czakó, L Vogel, EW Lamirande, KW Bock, IN Moore, AH Ellebedy, R Ahmed, A Mehle, K Subbarao	05/30/2017
Metabolic Phenotypes of Response to Vaccination in Humans. Cell	S Li, NL Sullivan, N Rouphael, T Yu, S Banton, MS Maddur, M McCausland, C Chiu, J Canniff, S Dubey, K Liu, V Tran, T Hagan, S Duraisingham, A Wieland, AK Mehta, JA Whitaker, S Subramaniam, DP Jones, A Sette, K Vora, A Weinberg, MJ Mulligan, HI Nakaya, M Levin, R Ahmed, B Pulendran	05/18/2017
Humoral cross-reactivity between Zika and dengue viruses: implications for protection and pathology. Emerging microbes & infections	L Priyamvada, W Hudson, R Ahmed, J Wrammert	05/10/2017
Proliferation of PD-1+ CD8 T cells in peripheral blood after PD-1-targeted therapy in lung cancer patients. Proceedings of the National Academy of Sciences of the United States of America	AO Kamphorst, RN Pillai, S Yang, TH Nasti, RS Akondy, A Wieland, GL Sica, K Yu, L Koenig, NT Patel, M Behera, H Wu, M McCausland, Z Chen, C Zhang, FR Khuri, TK Owonikoko, R Ahmed, SS Ramalingam	05/09/2017
Simply put: Vaccination saves lives. Proceedings of the National Academy of Sciences of the United States of America	WA Orenstein, R Ahmed	04/18/2017
Rescue of exhausted CD8 T cells by PD-1-targeted therapies is CD28-dependent. Science (New York, N.Y.)	AO Kamphorst, A Wieland, T Nasti, S Yang, R Zhang, DL Barber, BT Konieczny, CZ Daugherty, L Koenig, K Yu, GL Sica, AH Sharpe, GJ Freeman, BR Blazar, LA Turka, TK Owonikoko, RN Pillai, SS Ramalingam, K Araki, R Ahmed	03/31/2017
Adenovirus Serotype 5 Vaccination Results in Suboptimal CD4 T Helper 1 Responses in Mice. Journal of virology	J Lee, M Hashimoto, SJ Im, K Araki, HT Jin, CW Davis, BT Konieczny, GA Spies, MJ McElrath, R Ahmed	03/01/2017
Systems analysis of protective immune responses to RTS,S malaria vaccination in humans. Proceedings of the National Academy of Sciences of the United States of America	D Kazmin, HI Nakaya, EK Lee, MJ Johnson, R van der Most, RA van den Berg, WR Ballou, E Jongert, U Wille-Reece, C Ockenhouse, A Aderem, DE Zak, J Sadoff, J Hendriks, J Wrammert, R Ahmed, B Pulendran	02/28/2017
Dynamics of SIV-specific CXCR5+ CD8 T cells during chronic SIV infection. Proceedings of the National Academy of Sciences of the United States of America	GH Mylvaganam, D Rios, HM Abdelaal, S Iyer, G Tharp, M Mavigner, S Hicks, A Chahroudi, R Ahmed, SE Bosinger, IR Williams, PJ Skinner, V Velu, RR Amara	02/21/2017
mTOR Promotes Antiviral Humoral Immunity by Differentially Regulating CD4 Helper T Cell and B Cell Responses. Journal of virology	L Ye, J Lee, L Xu, AU Mohammed, W Li, JS Hale, WG Tan, T Wu, CW Davis, R Ahmed, K Araki	02/15/2017
IgG antibodies to dengue enhanced for FcγRIIIA binding determine disease severity. Science (New York, N.Y.)	TT Wang, J Sewatanon, MJ Memoli, J Wrammert, S Bournazos, SK Bhaumik, BA Pinsky, K Chokephaibulkit, N Onlamoon, K Pattanapanyasat, JK Taubenberger, R Ahmed, JV Ravetch	01/27/2017
Cardiac allograft rejection as a complication of PD-1 checkpoint blockade for cancer immunotherapy: a case report. Cancer immunology, immunotherapy : CII	TK Owonikoko, M Kumar, S Yang, AO Kamphorst, RN Pillai, R Akondy, V Nautiyal, MS Chatwal, WM Book, A Sahu, GL Sica, R Ahmed, SS Ramalingam	01/01/2017
Characterization of Human CD8 T Cell Responses in Dengue Virus-Infected Patients from India. Journal of virology	A Chandele, J Sewatanon, S Gunisetty, M Singla, N Onlamoon, RS Akondy, HT Kissick, K Nayak, ES Reddy, H Kalam, D Kumar, A Verma, H Panda, S Wang, N Angkasekwinai, K Pattanapanyasat, K Chokephaibulkit, GR Medigeshi, R Lodha, S Kabra, R Ahmed, K Murali-Krishna	12/15/2016
Direct Probing of Germinal Center Responses Reveals Immunological Features and Bottlenecks for Neutralizing Antibody Responses to HIV Env Trimer. Cell reports	C Havenar-Daughton, DG Carnathan, A Torrents de la Peña, M Pauthner, B Briney, SM Reiss, JS Wood, K Kaushik, MJ van Gils, SL Rosales, P van der Woude, M Locci, KM Le, SW de Taeye, D Sok, AUR Mohammed, J Huang, S Gumber, A Garcia, SP Kasturi, B Pulendran, JP Moore, R Ahmed, G Seumois, DR Burton, RW Sanders, G Silvestri, S Crotty	11/22/2016
Remembrance of Professor Steven Wechsler (1948-2016). Journal of neurovirology	R Ahmed, NW Fraser, H Ghiasi, C Jones	10/01/2016
Demethylation of the PD-1 Promoter Is Imprinted during the Effector Phase of CD8 T Cell Exhaustion. Journal of virology	E Ahn, B Youngblood, J Lee, J Lee, S Sarkar, R Ahmed	10/01/2016
Defining antigen-specific plasmablast and memory B cell subsets in human blood after viral infection or vaccination. Nature immunology	AH Ellebedy, KJ Jackson, HT Kissick, HI Nakaya, CW Davis, KM Roskin, AK McElroy, CM Oshansky, R Elbein, S Thomas, GM Lyon, CF Spiropoulou, AK Mehta, PG Thomas, SD Boyd, R Ahmed	10/01/2016
Defining CD8+ T cells that provide the proliferative burst after PD-1 therapy. Nature	SJ Im, M Hashimoto, MY Gerner, J Lee, HT Kissick, MC Burger, Q Shan, JS Hale, J Lee, TH Nasti, AH Sharpe, GJ Freeman, RN Germain, HI Nakaya, HH Xue, R Ahmed	09/15/2016
Kinetic Analysis of Biomarkers in a Cohort of US Patients With Ebola Virus Disease. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America	AK McElroy, JR Harmon, TD Flietstra, S Campbell, AK Mehta, CS Kraft, MG Lyon, JB Varkey, BS Ribner, CJ Kratochvil, PC Iwen, PW Smith, R Ahmed, ST Nichol, CF Spiropoulou	08/15/2016
Human antibody responses after dengue virus infection are highly cross-reactive to Zika virus. Proceedings of the National Academy of Sciences of the United States of America	L Priyamvada, KM Quicke, WH Hudson, N Onlamoon, J Sewatanon, S Edupuganti, K Pattanapanyasat, K Chokephaibulkit, MJ Mulligan, PC Wilson, R Ahmed, MS Suthar, J Wrammert	07/12/2016
B Cell Responses during Secondary Dengue Virus Infection Are Dominated by Highly Cross-Reactive, Memory-Derived Plasmablasts. Journal of virology	L Priyamvada, A Cho, N Onlamoon, NY Zheng, M Huang, Y Kovalenkov, K Chokephaibulkit, N Angkasekwinai, K Pattanapanyasat, R Ahmed, PC Wilson, J Wrammert	06/15/2016
Multi-epitope Models Explain How Pre-existing Antibodies Affect the Generation of Broadly Protective Responses to Influenza. PLoS pathogens	VI Zarnitsyna, J Lavine, A Ellebedy, R Ahmed, R Antia	06/01/2016
Humoral and Cell-Mediated Immune Responses to Alternate Booster Schedules of Anthrax Vaccine Adsorbed in Humans. Clinical and vaccine immunology : CVI	CP Quinn, CL Sabourin, JM Schiffer, NA Niemuth, VA Semenova, H Li, TL Rudge, AM Brys, RS Mittler, CC Ibegbu, J Wrammert, R Ahmed, SD Parker, J Babcock, W Keitel, GA Poland, HL Keyserling, H El Sahly, RM Jacobson, N Marano, BD Plikaytis, JG Wright	04/01/2016
CXCL13 is a plasma biomarker of germinal center activity. Proceedings of the National Academy of Sciences of the United States of America	C Havenar-Daughton, M Lindqvist, A Heit, JE Wu, SM Reiss, K Kendric, S Bélanger, SP Kasturi, E Landais, RS Akondy, HM McGuire, M Bothwell, PA Vagefi, E Scully, GD Tomaras, MM Davis, P Poignard, R Ahmed, BD Walker, B Pulendran, MJ McElrath, DE Kaufmann, S Crotty	03/08/2016
Saracatinib as a metastasis inhibitor in metastatic castration-resistant prostate cancer: A University of Chicago Phase 2 Consortium and DOD/PCF Prostate Cancer Clinical Trials Consortium Study. The Prostate	EM Posadas, RS Ahmed, T Karrison, RZ Szmulewitz, PH O'Donnell, JL Wade, J Shen, M Gururajan, M Sievert, WM Stadler	02/15/2016
Systems Analysis of Immunity to Influenza Vaccination across Multiple Years and in Diverse Populations Reveals Shared Molecular Signatures. Immunity	HI Nakaya, T Hagan, SS Duraisingham, EK Lee, M Kwissa, N Rouphael, D Frasca, M Gersten, AK Mehta, R Gaujoux, GM Li, S Gupta, R Ahmed, MJ Mulligan, S Shen-Orr, BB Blomberg, S Subramaniam, B Pulendran	12/15/2015
Immune history profoundly affects broadly protective B cell responses to influenza. Science translational medicine	SF Andrews, Y Huang, K Kaur, LI Popova, IY Ho, NT Pauli, CJ Henry Dunand, WM Taylor, S Lim, M Huang, X Qu, JH Lee, M Salgado-Ferrer, F Krammer, P Palese, J Wrammert, R Ahmed, PC Wilson	12/02/2015
The Interleukin-2-mTORc1 Kinase Axis Defines the Signaling, Differentiation, and Metabolism of T Helper 1 and Follicular B Helper T Cells. Immunity	JP Ray, MM Staron, JA Shyer, PC Ho, HD Marshall, SM Gray, BJ Laidlaw, K Araki, R Ahmed, SM Kaech, J Craft	10/20/2015
Two heads better than one? Ipilimumab immunotherapy and radiation therapy for melanoma brain metastases. Neuro-oncology	KR Patel, DH Lawson, RR Kudchadkar, BC Carthon, DE Oliver, D Okwan-Duodu, R Ahmed, MK Khan	10/01/2015
Subclassification of prostate cancer circulating tumor cells by nuclear size reveals very small nuclear circulating tumor cells in patients with visceral metastases. Cancer	JF Chen, H Ho, J Lichterman, YT Lu, Y Zhang, MA Garcia, SF Chen, AJ Liang, E Hodara, HE Zhau, S Hou, RS Ahmed, DJ Luthringer, J Huang, KC Li, LW Chung, Z Ke, HR Tseng, EM Posadas	09/15/2015
Cutting Edge: miR-17-92 Is Required for Both CD4 Th1 and T Follicular Helper Cell Responses during Viral Infection. Journal of immunology (Baltimore, Md. : 1950)	T Wu, A Wieland, J Lee, JS Hale, JH Han, X Xu, R Ahmed	09/15/2015
Masking of antigenic epitopes by antibodies shapes the humoral immune response to influenza. Philosophical transactions of the Royal Society of London. Series B, Biological sciences	VI Zarnitsyna, AH Ellebedy, C Davis, J Jacob, R Ahmed, R Antia	09/05/2015
Editorial overview: Vaccines: Vaccines for cancer and infectious diseases. Current opinion in immunology	JR Mascola, R Ahmed	08/01/2015
Corrigendum: An IL-27/NFIL3 signalling axis drives Tim-3 and IL-10 expression and T-cell dysfunction. Nature communications	C Zhu, K Sakuishi, S Xiao, Z Sun, S Zaghouani, G Gu, C Wang, DJ Tan, C Wu, M Rangachari, T Pertel, HT Jin, R Ahmed, AC Anderson, VK Kuchroo	07/08/2015
Anti-HA Glycoforms Drive B Cell Affinity Selection and Determine Influenza Vaccine Efficacy. Cell	TT Wang, J Maamary, GS Tan, S Bournazos, CW Davis, F Krammer, SJ Schlesinger, P Palese, R Ahmed, JV Ravetch	07/02/2015
Beyond adjuvants: immunomodulation strategies to enhance T cell immunity. Vaccine	AO Kamphorst, K Araki, R Ahmed	06/08/2015
NF-κB regulates PD-1 expression in macrophages. Journal of immunology (Baltimore, Md. : 1950)	AP Bally, P Lu, Y Tang, JW Austin, CD Scharer, R Ahmed, JM Boss	05/01/2015
Human Ebola virus infection results in substantial immune activation. Proceedings of the National Academy of Sciences of the United States of America	AK McElroy, RS Akondy, CW Davis, AH Ellebedy, AK Mehta, CS Kraft, GM Lyon, BS Ribner, J Varkey, J Sidney, A Sette, S Campbell, U Ströher, I Damon, ST Nichol, CF Spiropoulou, R Ahmed	04/14/2015
Initial viral load determines the magnitude of the human CD8 T cell response to yellow fever vaccination. Proceedings of the National Academy of Sciences of the United States of America	RS Akondy, PL Johnson, HI Nakaya, S Edupuganti, MJ Mulligan, B Lawson, JD Miller, B Pulendran, R Antia, R Ahmed	03/10/2015
Preexisting human antibodies neutralize recently emerged H7N9 influenza strains. The Journal of clinical investigation	CJ Henry Dunand, PE Leon, K Kaur, GS Tan, NY Zheng, S Andrews, M Huang, X Qu, Y Huang, M Salgado-Ferrer, IY Ho, W Taylor, R Hai, J Wrammert, R Ahmed, A García-Sastre, P Palese, F Krammer, PC Wilson	03/02/2015
Antibody effector functions mediated by Fcγ-receptors are compromised during persistent viral infection. Immunity	A Wieland, R Shashidharamurthy, AO Kamphorst, JH Han, RD Aubert, BP Choudhury, SR Stowell, J Lee, GA Punkosdy, MJ Shlomchik, P Selvaraj, R Ahmed	02/17/2015
An IL-27/NFIL3 signalling axis drives Tim-3 and IL-10 expression and T-cell dysfunction. Nature communications	C Zhu, K Sakuishi, S Xiao, Z Sun, S Zaghouani, G Gu, C Wang, DJ Tan, C Wu, M Rangachari, T Pertel, HT Jin, R Ahmed, AC Anderson, VK Kuchroo	01/23/2015
Malaria induces anemia through CD8+ T cell-dependent parasite clearance and erythrocyte removal in the spleen. mBio	I Safeukui, ND Gomez, AA Adelani, F Burte, NK Afolabi, R Akondy, P Velazquez, A Holder, R Tewari, P Buffet, BJ Brown, WA Shokunbi, D Olaleye, O Sodeinde, J Kazura, R Ahmed, N Mohandas, D Fernandez-Reyes, K Haldar	01/20/2015
Vaccine-elicited CD4 T cells induce immunopathology after chronic LCMV infection. Science (New York, N.Y.)	P Penaloza-MacMaster, DL Barber, EJ Wherry, NM Provine, JE Teigler, L Parenteau, S Blackmore, EN Borducchi, RA Larocca, KB Yates, H Shen, WN Haining, R Sommerstein, DD Pinschewer, R Ahmed, DH Barouch	01/16/2015
Reservoir host immune responses to emerging zoonotic viruses. Cell	JN Mandl, R Ahmed, LB Barreiro, P Daszak, JH Epstein, HW Virgin, MB Feinberg	01/15/2015
B cell responses to influenza infection and vaccination. Current topics in microbiology and immunology	C Chiu, AH Ellebedy, J Wrammert, R Ahmed	01/01/2015
Memory CD8 T cell transcriptional plasticity. F1000prime reports	B Youngblood, JS Hale, R Ahmed	01/01/2015
Reinvigorating Exhausted T Cells by Blockade of the PD-1 Pathway. Forum on immunopathological diseases and therapeutics	J Lee, E Ahn, HT Kissick, R Ahmed	01/01/2015
Memory T follicular helper CD4 T cells. Frontiers in immunology	JS Hale, R Ahmed	01/01/2015
High Affinity Antibodies against Influenza Characterize the Plasmablast Response in SLE Patients After Vaccination. PloS one	K Kaur, NY Zheng, K Smith, M Huang, L Li, NT Pauli, CJ Henry Dunand, JH Lee, M Morrissey, Y Wu, ML Joachims, ME Munroe, D Lau, X Qu, F Krammer, J Wrammert, P Palese, R Ahmed, JA James, PC Wilson	01/01/2015
Autophagy is essential for effector CD8(+) T cell survival and memory formation. Nature immunology	X Xu, K Araki, S Li, JH Han, L Ye, WG Tan, BT Konieczny, MW Bruinsma, J Martinez, EL Pearce, DR Green, DP Jones, HW Virgin, R Ahmed	12/01/2014
Corrigendum: Rapid generation of fully human monoclonal antibodies specific to a vaccinating antigen. Nature protocols	K Smith, L Garman, J Wrammert, NY Zheng, JD Capra, R Ahmed, PC Wilson	11/20/2014
Potential antigenic explanation for atypical H1N1 infections among middle-aged adults during the 2013-2014 influenza season. Proceedings of the National Academy of Sciences of the United States of America	SL Linderman, BS Chambers, SJ Zost, K Parkhouse, Y Li, C Herrmann, AH Ellebedy, DM Carter, SF Andrews, NY Zheng, M Huang, Y Huang, D Strauss, BH Shaz, RL Hodinka, G Reyes-Terán, TM Ross, PC Wilson, R Ahmed, JD Bloom, SE Hensley	11/04/2014
Induction of broadly cross-reactive antibody responses to the influenza HA stem region following H5N1 vaccination in humans. Proceedings of the National Academy of Sciences of the United States of America	AH Ellebedy, F Krammer, GM Li, MS Miller, C Chiu, J Wrammert, CY Chang, CW Davis, M McCausland, R Elbein, S Edupuganti, P Spearman, SF Andrews, PC Wilson, A García-Sastre, MJ Mulligan, AK Mehta, P Palese, R Ahmed	09/09/2014
Interplay between regulatory T cells and PD-1 in modulating T cell exhaustion and viral control during chronic LCMV infection. The Journal of experimental medicine	P Penaloza-MacMaster, AO Kamphorst, A Wieland, K Araki, SS Iyer, EE West, L O'Mara, S Yang, BT Konieczny, AH Sharpe, GJ Freeman, AY Rudensky, R Ahmed	08/25/2014
Dengue virus infection induces expansion of a CD14(+)CD16(+) monocyte population that stimulates plasmablast differentiation. Cell host & microbe	M Kwissa, HI Nakaya, N Onlamoon, J Wrammert, F Villinger, GC Perng, S Yoksan, K Pattanapanyasat, K Chokephaibulkit, R Ahmed, B Pulendran	07/09/2014
Biogenesis of influenza a virus hemagglutinin cross-protective stem epitopes. PLoS pathogens	JG Magadán, MO Altman, WL Ince, HD Hickman, J Stevens, A Chevalier, D Baker, PC Wilson, R Ahmed, JR Bennink, JW Yewdell	06/01/2014
STAT3, STAT4, NFATc1, and CTCF regulate PD-1 through multiple novel regulatory regions in murine T cells. Journal of immunology (Baltimore, Md. : 1950)	JW Austin, P Lu, P Majumder, R Ahmed, JM Boss	05/15/2014
Blimp-1 represses CD8 T cell expression of PD-1 using a feed-forward transcriptional circuit during acute viral infection. The Journal of experimental medicine	P Lu, BA Youngblood, JW Austin, AU Mohammed, R Butler, R Ahmed, JM Boss	03/10/2014
Differential impact of PD-1 and/or interleukin-10 blockade on HIV-1-specific CD4 T cell and antigen-presenting cell functions. Journal of virology	F Porichis, MG Hart, J Zupkosky, L Barblu, DS Kwon, A McMullen, T Brennan, R Ahmed, GJ Freeman, DG Kavanagh, DE Kaufmann	03/01/2014
Broadly reactive human CD8 T cells that recognize an epitope conserved between VZV, HSV and EBV. PLoS pathogens	C Chiu, M McCausland, J Sidney, FM Duh, N Rouphael, A Mehta, M Mulligan, M Carrington, A Wieland, NL Sullivan, A Weinberg, MJ Levin, B Pulendran, B Peters, A Sette, R Ahmed	03/01/2014
Vaccines at what price? Vaccine	DS Stephens, R Ahmed, WA Orenstein	02/19/2014
Molecular signatures of antibody responses derived from a systems biology study of five human vaccines. Nature immunology	S Li, N Rouphael, S Duraisingham, S Romero-Steiner, S Presnell, C Davis, DS Schmidt, SE Johnson, A Milton, G Rajam, S Kasturi, GM Carlone, C Quinn, D Chaussabel, AK Palucka, MJ Mulligan, R Ahmed, DS Stephens, HI Nakaya, B Pulendran	02/01/2014
PD-1 dependent exhaustion of CD8+ T cells drives chronic malaria. Cell reports	JM Horne-Debets, R Faleiro, DS Karunarathne, XQ Liu, KE Lineburg, CM Poh, GM Grotenbreg, GR Hill, KP MacDonald, MF Good, L Renia, R Ahmed, AH Sharpe, MN Wykes	12/12/2013
Identification of novel markers for mouse CD4(+) T follicular helper cells. European journal of immunology	SS Iyer, DR Latner, MJ Zilliox, M McCausland, RS Akondy, P Penaloza-Macmaster, JS Hale, L Ye, AU Mohammed, T Yamaguchi, S Sakaguchi, RR Amara, R Ahmed	12/01/2013
Host programmed death ligand 1 is dominant over programmed death ligand 2 expression in regulating graft-versus-host disease lethality. Blood	A Saha, K Aoyama, PA Taylor, BH Koehn, RG Veenstra, A Panoskaltsis-Mortari, DH Munn, WJ Murphy, M Azuma, H Yagita, BT Fife, MH Sayegh, N Najafian, G Socie, R Ahmed, GJ Freeman, AH Sharpe, BR Blazar	10/24/2013
Global DNA methylation remodeling accompanies CD8 T cell effector function. Journal of immunology (Baltimore, Md. : 1950)	CD Scharer, BG Barwick, BA Youngblood, R Ahmed, JM Boss	09/15/2013
Immunotherapy of chronic hepatitis C virus infection with antibodies against programmed cell death-1 (PD-1). Proceedings of the National Academy of Sciences of the United States of America	MJ Fuller, B Callendret, B Zhu, GJ Freeman, DL Hasselschwert, W Satterfield, AH Sharpe, LB Dustin, CM Rice, A Grakoui, R Ahmed, CM Walker	09/10/2013
CD4 T-cell immunotherapy for chronic viral infections and cancer. Immunotherapy	AO Kamphorst, R Ahmed	09/01/2013
In vitro assessment of the immunological significance of a human monoclonal antibody directed to the influenza a virus nucleoprotein. Clinical and vaccine immunology : CVI	R Bodewes, MM Geelhoed-Mieras, J Wrammert, R Ahmed, PC Wilson, RA Fouchier, AD Osterhaus, GF Rimmelzwaan	08/01/2013
Immune history shapes specificity of pandemic H1N1 influenza antibody responses. The Journal of experimental medicine	Y Li, JL Myers, DL Bostick, CB Sullivan, J Madara, SL Linderman, Q Liu, DM Carter, J Wrammert, S Esposito, N Principi, JB Plotkin, TM Ross, R Ahmed, PC Wilson, SE Hensley	07/29/2013
Cutting edge: Prolonged exposure to HIV reinforces a poised epigenetic program for PD-1 expression in virus-specific CD8 T cells. Journal of immunology (Baltimore, Md. : 1950)	B Youngblood, A Noto, F Porichis, RS Akondy, ZM Ndhlovu, JW Austin, R Bordi, FA Procopio, T Miura, TM Allen, J Sidney, A Sette, BD Walker, R Ahmed, JM Boss, RP Sékaly, DE Kaufmann	07/15/2013
Strength of PD-1 signaling differentially affects T-cell effector functions. Proceedings of the National Academy of Sciences of the United States of America	F Wei, S Zhong, Z Ma, H Kong, A Medvec, R Ahmed, GJ Freeman, M Krogsgaard, JL Riley	07/02/2013
T-cell memory differentiation: insights from transcriptional signatures and epigenetics. Immunology	B Youngblood, JS Hale, R Ahmed	07/01/2013
Interleukin-21 is a critical cytokine for the generation of virus-specific long-lived plasma cells. Journal of virology	MA Rasheed, DR Latner, RD Aubert, T Gourley, R Spolski, CW Davis, WA Langley, SJ Ha, L Ye, S Sarkar, V Kalia, BT Konieczny, WJ Leonard, R Ahmed	07/01/2013
Manipulating the PD-1 pathway to improve immunity. Current opinion in immunology	AO Kamphorst, R Ahmed	06/01/2013
Viral vaccines: past successes and future challenges. Current opinion in virology	R Ahmed, DR Burton	06/01/2013
PD-L1 blockade synergizes with IL-2 therapy in reinvigorating exhausted T cells. The Journal of clinical investigation	EE West, HT Jin, AU Rasheed, P Penaloza-Macmaster, SJ Ha, WG Tan, B Youngblood, GJ Freeman, KA Smith, R Ahmed	06/01/2013
Accelerating next-generation vaccine development for global disease prevention. Science (New York, N.Y.)	WC Koff, DR Burton, PR Johnson, BD Walker, CR King, GJ Nabel, R Ahmed, MK Bhan, SA Plotkin	05/31/2013
Pillars Article: Cytotoxic T-cell Memory without Antigen. Nature. 1994. 369: 648-652. Journal of immunology (Baltimore, Md. : 1950)	LL Lau, BD Jamieson, T Somasundaram, R Ahmed	05/01/2013
Distinct memory CD4+ T cells with commitment to T follicular helper- and T helper 1-cell lineages are generated after acute viral infection. Immunity	JS Hale, B Youngblood, DR Latner, AU Mohammed, L Ye, RS Akondy, T Wu, SS Iyer, R Ahmed	04/18/2013
Cross-reactive humoral responses to influenza and their implications for a universal vaccine. Annals of the New York Academy of Sciences	C Chiu, J Wrammert, GM Li, M McCausland, PC Wilson, R Ahmed	04/01/2013
AMPK: a metabolic switch for CD8+ T-cell memory. European journal of immunology	K Araki, R Ahmed	04/01/2013
Most influenza a virions fail to express at least one essential viral protein. Journal of virology	CB Brooke, WL Ince, J Wrammert, R Ahmed, PC Wilson, JR Bennink, JW Yewdell	03/01/2013
Comparative analysis of simian immunodeficiency virus gag-specific effector and memory CD8+ T cells induced by different adenovirus vectors. Journal of virology	WG Tan, HT Jin, EE West, P Penaloza-MacMaster, A Wieland, MJ Zilliox, MJ McElrath, DH Barouch, R Ahmed	02/01/2013
Programmed cell death 1-directed immunotherapy for enhancing T-cell function. Cold Spring Harbor symposia on quantitative biology	K Araki, B Youngblood, R Ahmed	01/01/2013
A randomized, double-blind, controlled trial of the 17D yellow fever virus vaccine given in combination with immune globulin or placebo: comparative viremia and immunogenicity. The American journal of tropical medicine and hygiene	S Edupuganti, RB Eidex, H Keyserling, RS Akondy, R Lanciotti, W Orenstein, C del Rio, Y Pan, T Querec, H Lipman, A Barrett, R Ahmed, D Teuwen, M Cetron, MJ Mulligan	01/01/2013
mTOR, linking metabolism and immunity. Seminars in immunology	X Xu, L Ye, K Araki, R Ahmed	12/01/2012
A three-dose intramuscular injection schedule of anthrax vaccine adsorbed generates sustained humoral and cellular immune responses to protective antigen and provides long-term protection against inhalation anthrax in rhesus macaques. Clinical and vaccine immunology : CVI	CP Quinn, CL Sabourin, NA Niemuth, H Li, VA Semenova, TL Rudge, HJ Mayfield, J Schiffer, RS Mittler, CC Ibegbu, J Wrammert, R Ahmed, AM Brys, RE Hunt, D Levesque, JE Estep, RE Barnewall, DM Robinson, BD Plikaytis, N Marano	11/01/2012
Progressive vaccinia: case description and laboratory-guided therapy with vaccinia immune globulin, ST-246, and CMX001. The Journal of infectious diseases	ER Lederman, W Davidson, HL Groff, SK Smith, T Warkentien, Y Li, KA Wilkins, KL Karem, RS Akondy, R Ahmed, M Frace, WJ Shieh, S Zaki, DE Hruby, WP Painter, KL Bergman, JI Cohen, IK Damon	11/01/2012
A Blueprint for HIV Vaccine Discovery. Cell host & microbe	DR Burton, R Ahmed, DH Barouch, ST Butera, S Crotty, A Godzik, DE Kaufmann, MJ McElrath, MC Nussenzweig, B Pulendran, CN Scanlan, WR Schief, G Silvestri, H Streeck, BD Walker, LM Walker, AB Ward, IA Wilson, R Wyatt	10/18/2012
ZBTB32 is an early repressor of the CIITA and MHC class II gene expression during B cell differentiation to plasma cells. Journal of immunology (Baltimore, Md. : 1950)	HS Yoon, CD Scharer, P Majumder, CW Davis, R Butler, W Zinzow-Kramer, I Skountzou, DG Koutsonanos, R Ahmed, JM Boss	09/01/2012
How do antigenically varying pathogens avoid cross-reactive responses to invariant antigens? Proceedings. Biological sciences	PL Johnson, BF Kochin, R Ahmed, R Antia	07/22/2012
Born this way? Understanding the immunological basis of effective HIV control. Nature immunology	MB Feinberg, R Ahmed	06/19/2012
Temporal expression of microRNA cluster miR-17-92 regulates effector and memory CD8+ T-cell differentiation. Proceedings of the National Academy of Sciences of the United States of America	T Wu, A Wieland, K Araki, CW Davis, L Ye, JS Hale, R Ahmed	06/19/2012
Pandemic H1N1 influenza vaccine induces a recall response in humans that favors broadly cross-reactive memory B cells. Proceedings of the National Academy of Sciences of the United States of America	GM Li, C Chiu, J Wrammert, M McCausland, SF Andrews, NY Zheng, JH Lee, M Huang, X Qu, S Edupuganti, M Mulligan, SR Das, JW Yewdell, AK Mehta, PC Wilson, R Ahmed	06/05/2012
CIITA promoter I CARD-deficient mice express functional MHC class II genes in myeloid and lymphoid compartments. Genes and immunity	WM Zinzow-Kramer, AB Long, BA Youngblood, KM Rosenthal, R Butler, AU Mohammed, I Skountzou, R Ahmed, BD Evavold, JM Boss	06/01/2012
Critical Role of STAT5 transcription factor tetramerization for cytokine responses and normal immune function. Immunity	JX Lin, P Li, D Liu, HT Jin, J He, M Ata Ur Rasheed, Y Rochman, L Wang, K Cui, C Liu, BL Kelsall, R Ahmed, WJ Leonard	04/20/2012
Rapid and massive virus-specific plasmablast responses during acute dengue virus infection in humans. Journal of virology	J Wrammert, N Onlamoon, RS Akondy, GC Perng, K Polsrila, A Chandele, M Kwissa, B Pulendran, PC Wilson, O Wittawatmongkol, S Yoksan, N Angkasekwinai, K Pattanapanyasat, K Chokephaibulkit, R Ahmed	03/01/2012
Acquired transcriptional programming in functional and exhausted virus-specific CD8 T cells. Current opinion in HIV and AIDS	B Youngblood, EJ Wherry, R Ahmed	01/01/2012
Re-engaging cross-reactive memory B cells: the influenza puzzle. Frontiers in immunology	AH Ellebedy, R Ahmed	01/01/2012
Protein energy malnutrition impairs homeostatic proliferation of memory CD8 T cells. Journal of immunology (Baltimore, Md. : 1950)	SS Iyer, JH Chatraw, WG Tan, EJ Wherry, TC Becker, R Ahmed, ZF Kapasi	01/01/2012
Antibody pressure by a human monoclonal antibody targeting the 2009 pandemic H1N1 virus hemagglutinin drives the emergence of a virus with increased virulence in mice. mBio	CD O'Donnell, L Vogel, A Wright, SR Das, J Wrammert, GM Li, M McCausland, NY Zheng, JW Yewdell, R Ahmed, PC Wilson, K Subbarao	01/01/2012
Antigen-specific CD4 T-cell help rescues exhausted CD8 T cells during chronic viral infection. Proceedings of the National Academy of Sciences of the United States of America	RD Aubert, AO Kamphorst, S Sarkar, V Vezys, SJ Ha, DL Barber, L Ye, AH Sharpe, GJ Freeman, R Ahmed	12/27/2011
TOR in the immune system. Current opinion in cell biology	K Araki, AH Ellebedy, R Ahmed	12/01/2011
Learning vaccinology from viral infections. The Journal of experimental medicine	R Ahmed, B Pulendran	11/21/2011
Human CD8⁺ and CD4⁺ T cell memory to lymphocytic choriomeningitis virus infection. Journal of virology	MF Kotturi, JA Swann, B Peters, CL Arlehamn, J Sidney, RV Kolla, EA James, RS Akondy, R Ahmed, WW Kwok, MJ Buchmeier, A Sette	11/01/2011
Moving ahead an HIV vaccine: use both arms to beat HIV. Nature medicine	BD Walker, R Ahmed, S Plotkin	10/11/2011
Chronic virus infection enforces demethylation of the locus that encodes PD-1 in antigen-specific CD8(+) T cells. Immunity	B Youngblood, KJ Oestreich, SJ Ha, J Duraiswamy, RS Akondy, EE West, Z Wei, P Lu, JW Austin, JL Riley, JM Boss, R Ahmed	09/23/2011
HIV-DNA priming alters T cell responses to HIV-adenovirus vaccine even when responses to DNA are undetectable. Journal of immunology (Baltimore, Md. : 1950)	SC De Rosa, EP Thomas, J Bui, Y Huang, A deCamp, C Morgan, SA Kalams, GD Tomaras, R Akondy, R Ahmed, CY Lau, BS Graham, GJ Nabel, MJ McElrath	09/15/2011
Tight regulation of memory CD8(+) T cells limits their effectiveness during sustained high viral load. Immunity	EE West, B Youngblood, WG Tan, HT Jin, K Araki, G Alexe, BT Konieczny, S Calpe, GJ Freeman, C Terhorst, WN Haining, R Ahmed	08/26/2011
4-1BB signaling synergizes with programmed death ligand 1 blockade to augment CD8 T cell responses during chronic viral infection. Journal of immunology (Baltimore, Md. : 1950)	V Vezys, P Penaloza-MacMaster, DL Barber, SJ Ha, B Konieczny, GJ Freeman, RS Mittler, R Ahmed	08/15/2011
Systems biology of vaccination for seasonal influenza in humans. Nature immunology	HI Nakaya, J Wrammert, EK Lee, L Racioppi, S Marie-Kunze, WN Haining, AR Means, SP Kasturi, N Khan, GM Li, M McCausland, V Kanchan, KE Kokko, S Li, R Elbein, AK Mehta, A Aderem, K Subbarao, R Ahmed, B Pulendran	07/10/2011
Opposing effects of CD70 costimulation during acute and chronic lymphocytic choriomeningitis virus infection of mice. Journal of virology	P Penaloza-MacMaster, A Ur Rasheed, SS Iyer, H Yagita, BR Blazar, R Ahmed	07/01/2011
Vaccination alters the balance between protective immunity, exhaustion, escape, and death in chronic infections. Journal of virology	PL Johnson, BF Kochin, MS McAfee, IM Stromnes, RR Regoes, R Ahmed, JN Blattman, R Antia	06/01/2011
Immunological mechanisms of vaccination. Nature immunology	B Pulendran, R Ahmed	06/01/2011
The role of LAT in increased CD8+ T cell exhaustion in trigeminal ganglia of mice latently infected with herpes simplex virus 1. Journal of virology	SJ Allen, P Hamrah, D Gate, KR Mott, D Mantopoulos, L Zheng, T Town, C Jones, UH von Andrian, GJ Freeman, AH Sharpe, L BenMohamed, R Ahmed, SL Wechsler, H Ghiasi	05/01/2011
Phenotype, function, and gene expression profiles of programmed death-1(hi) CD8 T cells in healthy human adults. Journal of immunology (Baltimore, Md. : 1950)	J Duraiswamy, CC Ibegbu, D Masopust, JD Miller, K Araki, GH Doho, P Tata, S Gupta, MJ Zilliox, HI Nakaya, B Pulendran, WN Haining, GJ Freeman, R Ahmed	04/01/2011
Sirolimus enhances the magnitude and quality of viral-specific CD8+ T-cell responses to vaccinia virus vaccination in rhesus macaques. American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons	AP Turner, VO Shaffer, K Araki, C Martens, PL Turner, S Gangappa, ML Ford, R Ahmed, AD Kirk, CP Larsen	03/01/2011
Insights into human CD8(+) T-cell memory using the yellow fever and smallpox vaccines. Immunology and cell biology	R Ahmed, RS Akondy	03/01/2011
Regulatory T-cell expansion during chronic viral infection is dependent on endogenous retroviral superantigens. Proceedings of the National Academy of Sciences of the United States of America	GA Punkosdy, M Blain, DD Glass, MM Lozano, L O'Mara, JP Dudley, R Ahmed, EM Shevach	03/01/2011
Phenotypic and functional profiling of malaria-induced CD8 and CD4 T cells during blood-stage infection with Plasmodium yoelii. Immunology	A Chandele, P Mukerjee, G Das, R Ahmed, VS Chauhan	02/01/2011
Broadly cross-reactive antibodies dominate the human B cell response against 2009 pandemic H1N1 influenza virus infection. The Journal of experimental medicine	J Wrammert, D Koutsonanos, GM Li, S Edupuganti, J Sui, M Morrissey, M McCausland, I Skountzou, M Hornig, WI Lipkin, A Mehta, B Razavi, C Del Rio, NY Zheng, JH Lee, M Huang, Z Ali, K Kaur, S Andrews, RR Amara, Y Wang, SR Das, CD O'Donnell, JW Yewdell, K Subbarao, WA Marasco, MJ Mulligan, R Compans, R Ahmed, PC Wilson	01/17/2011
Role of PD-1 in regulating T-cell immunity. Current topics in microbiology and immunology	HT Jin, R Ahmed, T Okazaki	01/01/2011
Bismuth breast and thyroid shield implementation for pediatric CT. Radiology management	M Dobbs, R Ahmed, LE Patrick	01/01/2011
From vaccines to memory and back. Immunity	F Sallusto, A Lanzavecchia, K Araki, R Ahmed	10/29/2010
Pathogenic virus-specific T cells cause disease during treatment with the calcineurin inhibitor FK506: implications for transplantation. The Journal of experimental medicine	K Araki, S Gangappa, DL Dillehay, BT Rouse, CP Larsen, R Ahmed	10/25/2010
Making memories that last a lifetime: heritable functions of self-renewing memory CD8 T cells. International immunology	B Youngblood, CW Davis, R Ahmed	10/01/2010
Homeostatic turnover of virus-specific memory CD8 T cells occurs stochastically and is independent of CD4 T cell help. Journal of immunology (Baltimore, Md. : 1950)	DK Choo, K Murali-Krishna, R Anita, R Ahmed	09/15/2010
Cooperation of Tim-3 and PD-1 in CD8 T-cell exhaustion during chronic viral infection. Proceedings of the National Academy of Sciences of the United States of America	HT Jin, AC Anderson, WG Tan, EE West, SJ Ha, K Araki, GJ Freeman, VK Kuchroo, R Ahmed	08/17/2010
Cutting edge: Rapamycin augments pathogen-specific but not graft-reactive CD8+ T cell responses. Journal of immunology (Baltimore, Md. : 1950)	IR Ferrer, ME Wagener, JM Robertson, AP Turner, K Araki, R Ahmed, AD Kirk, CP Larsen, ML Ford	08/15/2010
Qualitatively different memory CD8+ T cells are generated after lymphocytic choriomeningitis virus and influenza virus infections. Journal of immunology (Baltimore, Md. : 1950)	SN Mueller, WA Langley, G Li, A García-Sastre, RJ Webby, R Ahmed	08/15/2010
PD-L1 has distinct functions in hematopoietic and nonhematopoietic cells in regulating T cell responses during chronic infection in mice. The Journal of clinical investigation	SN Mueller, VK Vanguri, SJ Ha, EE West, ME Keir, JN Glickman, AH Sharpe, R Ahmed	07/01/2010
The role of mTOR in memory CD8 T-cell differentiation. Immunological reviews	K Araki, B Youngblood, R Ahmed	05/01/2010
Features of responding T cells in cancer and chronic infection. Current opinion in immunology	PS Kim, R Ahmed	04/01/2010
Dynamic T cell migration program provides resident memory within intestinal epithelium. The Journal of experimental medicine	D Masopust, D Choo, V Vezys, EJ Wherry, J Duraiswamy, R Akondy, J Wang, KA Casey, DL Barber, KS Kawamura, KA Fraser, RJ Webby, V Brinkmann, EC Butcher, KA Newell, R Ahmed	03/15/2010
Immunization with live attenuated influenza viruses that express altered NS1 proteins results in potent and protective memory CD8+ T-cell responses. Journal of virology	SN Mueller, WA Langley, E Carnero, A García-Sastre, R Ahmed	02/01/2010
Prolonged interleukin-2Ralpha expression on virus-specific CD8+ T cells favors terminal-effector differentiation in vivo. Immunity	V Kalia, S Sarkar, S Subramaniam, WN Haining, KA Smith, R Ahmed	01/29/2010
CD8 T-cell memory differentiation during acute and chronic viral infections. Advances in experimental medicine and biology	V Kalia, S Sarkar, R Ahmed	01/01/2010
The yellow fever virus vaccine induces a broad and polyfunctional human memory CD8+ T cell response. Journal of immunology (Baltimore, Md. : 1950)	RS Akondy, ND Monson, JD Miller, S Edupuganti, D Teuwen, H Wu, F Quyyumi, S Garg, JD Altman, C Del Rio, HL Keyserling, A Ploss, CM Rice, WA Orenstein, MJ Mulligan, R Ahmed	12/15/2009
T-cell reconstitution without T-cell immunopathology in two models of T-cell-mediated tissue destruction. Immunology	P Penaloza-MacMaster, D Masopust, R Ahmed	10/01/2009
The precursors of memory: models and controversies. Nature reviews. Immunology	R Ahmed, MJ Bevan, SL Reiner, DT Fearon	09/01/2009
Redefining chronic viral infection. Cell	HW Virgin, EJ Wherry, R Ahmed	07/10/2009
mTOR regulates memory CD8 T-cell differentiation. Nature	K Araki, AP Turner, VO Shaffer, S Gangappa, SA Keller, MF Bachmann, CP Larsen, R Ahmed	07/02/2009
High antigen levels are the cause of T cell exhaustion during chronic viral infection. Proceedings of the National Academy of Sciences of the United States of America	SN Mueller, R Ahmed	05/26/2009
Impact of epitope escape on PD-1 expression and CD8 T-cell exhaustion during chronic infection. Journal of virology	JN Blattman, EJ Wherry, SJ Ha, RG van der Most, R Ahmed	05/01/2009
Visualizing antigen-specific and infected cells in situ predicts outcomes in early viral infection. Science (New York, N.Y.)	Q Li, PJ Skinner, SJ Ha, L Duan, TL Mattila, A Hage, C White, DL Barber, L O'Mara, PJ Southern, CS Reilly, JV Carlis, CJ Miller, R Ahmed, AT Haase	03/27/2009
Enhancing SIV-specific immunity in vivo by PD-1 blockade. Nature	V Velu, K Titanji, B Zhu, S Husain, A Pladevega, L Lai, TH Vanderford, L Chennareddi, G Silvestri, GJ Freeman, R Ahmed, RR Amara	03/12/2009
Human immune memory to yellow fever and smallpox vaccination. Journal of clinical immunology	J Wrammert, J Miller, R Akondy, R Ahmed	03/01/2009
Requirement of B cells for generating CD4+ T cell memory. Journal of immunology (Baltimore, Md. : 1950)	JK Whitmire, MS Asano, SM Kaech, S Sarkar, LG Hannum, MJ Shlomchik, R Ahmed	02/15/2009
Memory CD8 T-cell compartment grows in size with immunological experience. Nature	V Vezys, A Yates, KA Casey, G Lanier, R Ahmed, R Antia, D Masopust	01/08/2009
Frequency and phenotype of human immunodeficiency virus envelope-specific B cells from patients with broadly cross-neutralizing antibodies. Journal of virology	NA Doria-Rose, RM Klein, MM Manion, S O'Dell, A Phogat, B Chakrabarti, CW Hallahan, SA Migueles, J Wrammert, R Ahmed, M Nason, RT Wyatt, JR Mascola, M Connors	01/01/2009
Systems biology approach predicts immunogenicity of the yellow fever vaccine in humans. Nature immunology	TD Querec, RS Akondy, EK Lee, W Cao, HI Nakaya, D Teuwen, A Pirani, K Gernert, J Deng, B Marzolf, K Kennedy, H Wu, S Bennouna, H Oluoch, J Miller, RZ Vencio, M Mulligan, A Aderem, R Ahmed, B Pulendran	01/01/2009
Rapid generation of fully human monoclonal antibodies specific to a vaccinating antigen. Nature protocols	K Smith, L Garman, J Wrammert, NY Zheng, JD Capra, R Ahmed, PC Wilson	01/01/2009
NFATc1 regulates PD-1 expression upon T cell activation. Journal of immunology (Baltimore, Md. : 1950)	KJ Oestreich, H Yoon, R Ahmed, JM Boss	10/01/2008
Cholera toxin-specific memory B cell responses are induced in patients with dehydrating diarrhea caused by Vibrio cholerae O1. The Journal of infectious diseases	CR Jayasekera, JB Harris, S Bhuiyan, F Chowdhury, AI Khan, AS Faruque, RC Larocque, ET Ryan, R Ahmed, F Qadri, SB Calderwood	10/01/2008
Case of yellow fever vaccine--associated viscerotropic disease with prolonged viremia, robust adaptive immune responses, and polymorphisms in CCR5 and RANTES genes. The Journal of infectious diseases	B Pulendran, J Miller, TD Querec, R Akondy, N Moseley, O Laur, J Glidewell, N Monson, T Zhu, H Zhu, S Staprans, D Lee, MA Brinton, AA Perelygin, C Vellozzi, P Brachman, S Lalor, D Teuwen, RB Eidex, M Cetron, F Priddy, C del Rio, J Altman, R Ahmed	08/15/2008
Lymphoid stroma in the initiation and control of immune responses. Immunological reviews	SN Mueller, R Ahmed	08/01/2008
Identification of an evolutionarily conserved transcriptional signature of CD8 memory differentiation that is shared by T and B cells. Journal of immunology (Baltimore, Md. : 1950)	WN Haining, BL Ebert, A Subrmanian, EJ Wherry, Q Eichbaum, JW Evans, R Mak, S Rivoli, J Pretz, J Angelosanto, JS Smutko, BD Walker, SM Kaech, R Ahmed, LM Nadler, TR Golub	08/01/2008
Unraveling the role of PD-1/PD-L interactions in persistent hepatotropic infections: potential for therapeutic application? Gastroenterology	H Radziewicz, HL Hanson, R Ahmed, A Grakoui	06/01/2008
Manipulating both the inhibitory and stimulatory immune system towards the success of therapeutic vaccination against chronic viral infections. Immunological reviews	SJ Ha, EE West, K Araki, KA Smith, R Ahmed	06/01/2008
Rapid cloning of high-affinity human monoclonal antibodies against influenza virus. Nature	J Wrammert, K Smith, J Miller, WA Langley, K Kokko, C Larsen, NY Zheng, I Mays, L Garman, C Helms, J James, GM Air, JD Capra, R Ahmed, PC Wilson	05/29/2008
Maintenance of serological memory. Biological chemistry	J Wrammert, R Ahmed	05/01/2008
Human effector and memory CD8+ T cell responses to smallpox and yellow fever vaccines. Immunity	JD Miller, RG van der Most, RS Akondy, JT Glidewell, S Albott, D Masopust, K Murali-Krishna, PL Mahar, S Edupuganti, S Lalor, S Germon, C Del Rio, MJ Mulligan, SI Staprans, JD Altman, MB Feinberg, R Ahmed	05/01/2008
Diminished primary CD8 T cell response to viral infection during protein energy malnutrition in mice is due to changes in microenvironment and low numbers of viral-specific CD8 T cell precursors. The Journal of nutrition	JH Chatraw, EJ Wherry, R Ahmed, ZF Kapasi	04/01/2008
Immune responsiveness and protective immunity after transplantation. Transplant international : official journal of the European Society for Organ Transplantation	S Gangappa, KE Kokko, LM Carlson, T Gourley, KA Newell, TC Pearson, R Ahmed, CP Larsen	04/01/2008
Enhancing therapeutic vaccination by blocking PD-1-mediated inhibitory signals during chronic infection. The Journal of experimental medicine	SJ Ha, SN Mueller, EJ Wherry, DL Barber, RD Aubert, AH Sharpe, GJ Freeman, R Ahmed	03/17/2008
Functional and genomic profiling of effector CD8 T cell subsets with distinct memory fates. The Journal of experimental medicine	S Sarkar, V Kalia, WN Haining, BT Konieczny, S Subramaniam, R Ahmed	03/17/2008
Localization of CD8+ cells specific for hepatitis B virus surface protein in the liver of immunized mice. Journal of medical virology	D Qu, G Lanier, ZH Yuan, YM Wen, CR Howard, R Ahmed	02/01/2008
Fine-tuning CD4+ central memory T cell heterogeneity by strength of stimulation. European journal of immunology	V Kalia, S Sarkar, R Ahmed	01/01/2008

Awards

Dr. Ahmed is one of two immunologists to receive the 2017 Robert Koch Award. In 2018, he was named a fellow of the National Academy of Inventors. He received the Award for Distinguished Research in the Biomedical Sciences from the Association of American Medical Colleges in 2019.

Dr. Ahmed received the 2014 Emory 1% Award, which recognizes Emory faculty whose National Institutes of Health (NIH) proposals have been ranked in the top 1% by NIH reviewers. He has been named multiple times to the MilliPub Club, which recognizes current Emory faculty who have published one or more individual papers throughout their careers that have garnered more than 1,000 citations.