Titles and Roles
- Associate Professor, Department of Pediatrics
- Emory University School of Medicine
- Scientific Director, Pediatrics/Winship Flow Cytometry Core
- Children's Healthcare of Atlanta and Winship Cancer Institute of Emory University
David R. Archer, PhD, is Associate Professor in the Department of Pediatrics of Emory University School of Medicine. Dr. Archer serves as the scientific director of the Pediatrics/Winship Flow Cytometry Core at Childrens' Healthcare of Atlanta and Winship Cancer Institute of Emory University.
Dr. Archer's research interests are focused on the pathogenesis of sickle cell disease in respect to the generation, prevention and treatment of organ dysfunction. His lab's studies on the pathogenesis of sickle cell nephropathy are likely to examine the role of endothelial cells in the generation of both the proteinuria and the concentrating defects associated with renal dysfunction. In particular, his lab employs hematopoietic stem cell transplantation to correct the hematological defect in murine models of sickle cell disease.
His lab has considerable experience in the maintenance of sickle mouse colonies, transplantation, hematological and functional analysis of the outcomes. In their collaborative projects, these skills enable them to generate the sickle phenotype in the models of oxidant stress included in this project and therefore allow them to investigate the role of various oxidant response genes in the pathogenesis of sickle vasculopathy.
Publications Publication Date