Kevin Bunting, PhD

P0053864

Titles and Roles

Professor, Department of Pediatrics, Division of Hematology and Oncology
Emory University School of Medicine
Aflac Field Force Cancer Innovative Therapy Chair
Aflac Cancer and Blood Disorders Center
Research Director, Leukemia and Lymphoma
Aflac Cancer and Blood Disorders Center
Research Program
Cancer Cell Biology

Biography

Kevin Bunting, PhD, is Professor in the Division of Hematology and Oncology in the Department of Pediatrics at Emory University School of Medicine. He is a member of the Cancer Cell Biology Research Program at Winship Cancer Institute of Emory University. He also holds memberships with the American Society of Hematology, the American Association for Cancer Research, and the American Association for the Advancement of Science. 

Education

Dr. Bunting earned his medical degree from Wake Forest University in Winston-Salem, North Carolina. He then went on to complete a fellowship in Experimental Hematology at St. Jude Children’s Research Hospital in Memphis, Tennessee. 

Research

Dr. Bunting's research is focused on understanding the biology of the latent transcription factor STAT5, in particular its roles in normal hematopoietic stem cell function and its aberrant activation associated with a variety of hematologic malignancies. Activation of STAT5 by phosphorylation is required at tightly regulated levels for normal hematopoiesis but its persistent activation is prevalent in adult and pediatric leukemias. A major focus of the Bunting lab is to identify keySTAT5 downstream target genes associated with both normal and leukemic hematopoietic cell function and to utilize this knowledge to develop novel approaches to manipulate STAT5 activity in a therapeutic setting. In leukemia therapy, the goal is to disengage leukemic cell survival and to facilitate leukemia cell sensitivity in combination with other targeted agents. In hematopoietic stem cell transplantation, the goal is to develop innovative forms of conditioning based on STAT5 signaling inhibition.

Publications

Dr. Bunting has authored/co-authored numerous publications, journal articles and journal abstracts. 

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Awards

In 2013, Dr. Buntington received the Emory Millipub Club for having published one or more individual papers throughout his career that have garnered more than 1,000 citations.

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