Titles and Roles
- Assistant Professor, Department of Pediatrics
- Emory University School of Medicine
- Pediatric Oncologist
- Pediatric Cancer
- Research Program
- Cancer Cell Biology
Dr. Castellino received his medical degree from Duke University, Durham, NC in 1999. He completed his residency in pediatrics at Harvard Medical School and Massachusetts General Hospital, Boston, MA in 2002. He completed his fellowship in pediatric hematology and oncology at Texas Children's Cancer Center at Baylor College of Medicine, Houston, TX in 2005.
Dr. Castellino has been the recipient of numerous awards. He was named a Duke Futures Scholar and received a North Carolina Scholars Scholarship, General Motors Full-Tuition Scholarship, Hillory M. Wilder Endowed Scholarship, and Medical School Faculty Wives Club Endowed Scholarship. He completed the Charles Stark Draper Fellowship in Aeronautics at M.I.T. in 1993 and the Medical Student Summer Fellowship at Duke University in 1998.
Dr. Castellino is or has been the recipient of the NIH T32 Pediatric Training Award, the Stephanie Kramer/American Brain Tumor Association Translational Brain Tumor Research Grant, the NIH Molecular Medicine Scholar Award, Alex’s Lemonade Stand Foundation Young Investigator Award, the Bear Necessities Pediatric Cancer Foundation, Junior Investigator Award, the AACR-Aflac, Inc. Career Development Award for Pediatric Cancer Research, the CURE Childhood Cancer Foundation Research Award, the St. Baldrick’s Foundation Career Development (Scholar) Award, the Emory Egleston Children’s Research Center Seed Grant, Winship Cancer Institute Molecular Pathways and Biomarkers Program Seed Grant, Southeastern Brain Tumor Foundation Research Grant, the Scholar Award-Competitive Extension from St. Baldrick’s Foundation, the Pediatric Research Center for Neuroscience Pilot Grant, and the Alex’s Lemonade Stand Foundation Springboard Grant.
Dr. Castellino was also featured on CNN Health Update as a St. Baldrick’s Foundation Scholar in 2009 and received an NIH/NCI R01 for Mechanisms of PPM1D in medulloblastoma tumorigenesis and invasion at Emory University for 2013-2018.
Dr. Castellino’s research focuses on PPM1D-mediated signaling pathways that divert normal brain development toward growth and dissemination of medulloblastoma or DIPG. His team uses in vitro assays, mouse models, and patient-derived tissues to understand signaling in growth, treatment resistance, and response to novel PPM1D-targeted therapies to improve survival and outcome in children.