Jae Won Chang, PhD
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Research Program
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Phone Number
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Email Address
Biography
Jae Won Chang, PhD, holds a joint appointment as an assistant professor in the Department of Pharmacology and Chemical Biology, and the Department of Hematology and Medical Oncology at Emory University School of Medicine. Dr. Chang is a member of the Discovery and Developmental Therapeutics Research Program at Winship Cancer Institute.
Education
Dr. Chang earned his PhD in Chemistry and Chemical Biology at The Scripps Research Institute as a California Institute for Regenerative Medicine Predoctoral Fellow.
Titles & Roles
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Assistant Professor, Department of Pharmacology and Chemical BiologyEmory University School of Medicine
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Assistant Professor, Department of Hematology and Medical OncologyEmory University School of Medicine
Research
Dr. Chang's research interests have concentrated on developing novel chemical probes to solve problems in various fields including chemical biology, chemical proteomics, metabolomics, medicinal chemistry and molecular imaging, as well as challenges in modern biology such as cancer therapy. The chemical probes would be useful for the development of potent and specific drugs targeting poorly characterized proteins from the earliest stages of target validation through medicinal chemistry optimization and even through pharmacodynamic studies during clinical trials.
Publications
| Title/Journal | Authors | Publication Date |
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Angewandte Chemie (International ed. in English) |
J Song, T Zhai, HS Hahm, Y Li, H Mao, X Wang, J Jo, JW Chang | 06/27/2024 |
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Cancer discovery |
BD Stein, JR Ferrarone, EE Gardner, JW Chang, D Wu, PE Hollstein, RJ Liang, M Yuan, Q Chen, JS Coukos, M Sindelar, B Ngo, SS Gross, RJ Shaw, C Zhang, JM Asara, RE Moellering, H Varmus, LC Cantley | 04/03/2023 |
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Recent advances in development of hetero-bivalent kinase inhibitors. European journal of medicinal chemistry |
S Lee, J Kim, J Jo, JW Chang, J Sim, H Yun | 04/15/2021 |
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In Vivo Imaging of the Tumor-Associated Enzyme NCEH1 with a Covalent PET Probe. Angewandte Chemie (International ed. in English) |
JW Chang, M Bhuiyan, HM Tsai, HJ Zhang, G Li, S Fathi, DC McCutcheon, L Leoni, R Freifelder, CT Chen, RE Moellering | 08/24/2020 |
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Proceedings of the National Academy of Sciences of the United States of America |
G Li, MA Eckert, JW Chang, JE Montgomery, A Chryplewicz, E Lengyel, RE Moellering | 10/22/2019 |