Zhihong Chen, PhD, MSc


Titles and Roles

Instructor, Department of Pediatrics
Emory University School of Medicine
Research Program
Discovery and Developmental Therapeutics


Zhihong "Z" Chen, PhD, MSc, is an Instructor in the Department of Pediatrics at Emory University School of Medicine. Dr. Chen has broad expertise in neurosciences and immunology, and in cutting-edge technologies such as 3D electron microscopy, multiphoton microscopy, fluorescence assisted cell sorting, and laser-capture microdissection.


Dr. Chen received a Master's degree in Biochemistry from China Pharmaceutical University in Nanjing, China and a PhD degree in Immunology from the University of Ottawa in Ottawa, Canada. He completed a postdoctoral training at the Cleveland Clinic in Cleveland, Ohio.


Dr. Chen's research focuses on the innate immunity in various diseases of the central nervous system. He has demonstrated that gammadelta T-cells are capable of inflicting injuries to brain tissue in multiple sclerosis patients via a cytotoxic mechanism termed "ADCC'. He has also found that microglia, the resident macrophage of the central nervous system, can protect the brain from traumatic injury.

His current work in the lab of Dr. Dolores Hambardzumyan investigates how peripheral monocytes and central nervous system microglia differentially contribute to glioblastoma development in relevance to different glioblastoma multiforme subtypes.


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