Max D. Cooper, MD

Titles and Roles

Professor, Department of Pathology & Laboratory Medicine
Emory University School of Medicine
Professor, Emory Vaccine Center
Emory University School of Medicine
Investigator, Emory Center for AIDS Research
Emory University School of Medicine
Research Program
Cancer Cell Biology

Biography

A Georgia Research Alliance Eminent Scholar, Dr. Carlson's laboratory is involved in studies that explore the use of lamprey monoclonal antibodies for diagnosis and therapy of infectious diseases and lymphoid malignancies. 

Education

Dr. Cooper obtained his medical degree and pediatric residency training from Tulane University Medical School.

Research

For many years, Dr. Cooper and his colleagues have been engaged in comparative studies of normal lymphocyte development and function with a special emphasis on B lineage cells. They have used this information to study defects of B cell differentiation in individuals with immunodeficiency diseases, lymphoid malignancies and autoimmune diseases. Highlights of their research accomplishments include the delineation of separate T and B cell lineages, identification of the hematopoietic tissue origin of B lineage cells, identification of precursor B cells, demonstration that IgM-bearing B lymphocytes give rise to B cells that switch to the production of other Ig isotypes, initial description of the lymphoid follicle associated epithelial "M" cells in the intestine and their transcytotic function, and discovery of an alternative adaptive immune system in jawless vertebrates featuring antigen receptors generated by the assembly of leucine-rich-repeat sequences during development of T-like and B-like lymphocyte lineages. Current studies focus on evolution of the adaptive immune system, the development of monoclonal lamprey antibodies for biomedical uses, and the immunoregulatory roles of Fc receptor-like molecules (FCRL1-5) expressed by human B cells, with an emphasis on memory B cells.

Publications

Dr. Cooper is an editor of several immunological journals and past president of the Clinical Immunology Society, the American Association of Immunologists and the Kunkel Society.

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