Ahmet F. Coskun, PhD

Research Program

Cell and Molecular Biology
Phone Number

404-894-3866
Email Address

ahmet.coskun@bme.gatech.edu

Biography

Ahmet F. Coskun, PhD, is an associate professor and the Bernie-Marcus Early-Career Professor in the Wallace H. Coulter Department of Biomedical Engineering at Georgia Tech School of Engineering and Emory University School of Medicine.

Dr. Coskun is a member of the Cell and Molecular Biology Research Program at Winship Cancer Institute of Emory University in Atlanta, Georgia.

Education

Dr. Coskun received his PhD in Electrical Engineering and Bioengineering from the University of California, Los Angeles. He completed his postdoctoral training at the California Institute of Technology and at the Beckman Research Institute.

Titles & Roles

Associate Professor, Wallace H. Coulter Department of Biomedical Engineering

Georgia Institute of Technology and Emory University
Bernie Marcus Early-Career Professor, Wallace H. Coulter Department of Biomedical Engineering

Georgia Institute of Technology and Emory University

Research

Coskun is a systems biotechnologist and bioengineer, working at the nexus of multiplexed cell imaging and quantitative tissue biology. He directs an interdisciplinary research team at the Single Cell Biotechnology and Spatial Omics Laboratory, an interdisciplinary program strategically positioned for multiparameter imaging one cell at a time by spatial context and function.

Publications

Coskun holds five issued patents and is also the co-author of more than 50 peer-reviewed publications in major scientific journals.

Title/Journal	Authors	Publication Date
Untangling the Fusion of Spatial Omics and Mechanobiology. Progress in biomedical engineering (Bristol, England)	S Dembowitz, FR Moctezuma, N Zhang, A Venkataraman, AF Coskun	10/23/2025
An immune-competent lung-on-a-chip for modelling the human severe influenza infection response. Nature biomedical engineering	R Ringquist, E Bhatia, P Chatterjee, D Maniar, Z Fang, P Franz, L Kramer, D Ghoshal, N Sonthi, E Downey, J Canlas, A Ochal, S Agarwal, V Cuéllar, G Harrigan, AF Coskun, A Singh, K Roy	09/23/2025
Modular, open-sourced multiplexing for democratizing spatial omics. Lab on a chip	N Zhang, Z Fang, P Kadakia, J Guo, D Vijay, M Thapa, S Dembowitz, A Grakoui, AF Coskun	09/12/2025
Spatial morphoproteomic features predict disease states from tissue architectures. iScience	T Hu, E Ozturk, M Allam, N Nishkala, V Kaushik, SL Goudy, Q Xu, P Mudd, K Manthiram, AF Coskun	08/15/2025
Spatially resolved subcellular protein-protein interactomics in drug-perturbed lung-cancer cultures and tissues. Nature biomedical engineering	S Cai, T Hu, A Venkataraman, FG Rivera Moctezuma, E Ozturk, N Zhang, M Wang, T Zvidzai, S Das, A Pillai, F Schneider, SS Ramalingam, YT Oh, SY Sun, AF Coskun	07/01/2025
Multi-niche human bone marrow on-a-chip for studying the interactions of adoptive CAR-T cell therapies with multiple myeloma. Biomaterials	D Ghoshal, I Petersen, R Ringquist, L Kramer, E Bhatia, T Hu, A Richard, R Park, J Corbin, S Agarwal, A Thomas, S Ramirez, J Tharayil, E Downey, F Ketchum, A Ochal, N Sonthi, S Lonial, JN Kochenderfer, R Tran, M Zhu, WA Lam, AF Coskun, K Roy	05/01/2025
Clinically relevant clot resolution via a thromboinflammation-on-a-chip. Nature	Y Qiu, J Lin, A Wang, Z Fang, Y Sakurai, H Choi, EK Williams, ET Hardy, K Maher, AF Coskun, G Woods, WA Lam	05/01/2025
Microbial Changes Occurring During Oronasal Fistula Wound Healing. Microorganisms	SL Goudy, HL Bradley, CA Gacasan, A Toma, KPC Sekar, WM Wuest, M Tomov, V Serpooshan, A Coskun, RM Jones	02/02/2025
Human immune organoids to decode B cell response in healthy donors and patients with lymphoma. Nature materials	Z Zhong, M Quiñones-Pérez, Z Dai, VM Juarez, E Bhatia, CR Carlson, SB Shah, A Patel, Z Fang, T Hu, M Allam, SL Hicks, M Gupta, SL Gupta, E Weeks, SD Vagelos, A Molina, A Mulero-Russe, A Mora-Boza, DJ Joshi, RP Sekaly, T Sulchek, SL Goudy, J Wrammert, K Roy, JM Boss, AF Coskun, CD Scharer, AJ García, JL Koff, A Singh	02/01/2025
Graph-Based 3-Dimensional Spatial Gene Neighborhood Networks of Single Cells in Gels and Tissues. BME frontiers	Z Fang, K Krusen, H Priest, M Wang, S Kim, A Sriram, A Yellanki, A Singh, E Horwitz, AF Coskun	01/01/2025
High cell throughput, programmable fixation reveals the RNA and protein co-regulation with spatially resolved NFκB pseudo-signaling. APL bioengineering	N Zhang, M Wang, D Nambiar, S Iyer, P Kadakia, Q Luo, S Pang, A Qu, NS Bharadwaj, P Qiu, AF Coskun	12/01/2024
Decoding senescence of aging single cells at the nexus of biomaterials, microfluidics, and spatial omics. npj aging	A Venkataraman, I Kordic, J Li, N Zhang, NS Bharadwaj, Z Fang, S Das, AF Coskun	11/26/2024
Super Resolved Single-Cell Spatial Metabolomics from Multimodal Mass Spectrometry Imaging guided by Imaging Mass Cytometry. bioRxiv : the preprint server for biology	E Ozturk, A Venkataraman, FG Rivera Moctezuma, AF Coskun	10/24/2024
Graph-Based Spatial Proximity of Super-Resolved Protein-Protein Interactions Predicts Cancer Drug Responses in Single Cells. Cellular and molecular bioengineering	N Zhang, S Cai, M Wang, T Hu, F Schneider, SY Sun, AF Coskun	10/01/2024
Combining spatial metabolomics and proteomics profiling of single cells. Nature reviews. Immunology	M Allam, AF Coskun	10/01/2024
Spatial immunophenotyping using multiplexed imaging of immune follicles in secondary lymphoid tissues. PNAS nexus	M Allam, T Hu, Z Fang, M Pi, A Singh, AF Coskun	08/01/2024
Multi-Niche Human Bone Marrow On-A-Chip for Studying the Interactions of Adoptive CAR-T Cell Therapies with Multiple Myeloma. bioRxiv : the preprint server for biology	D Ghoshal, I Petersen, R Ringquist, L Kramer, E Bhatia, T Hu, A Richard, R Park, J Corbin, S Agarwal, A Thomas, S Ramirez, J Tharayil, E Downey, F Ketchum, A Ochal, N Sonthi, S Lonial, JN Kochenderfer, R Tran, M Zhu, WA Lam, AF Coskun, K Roy	04/12/2024
Comprehensive biomechanical and anatomical atherosclerotic plaque metrics predict major adverse cardiovascular events: A new tool for clinical decision making. Atherosclerosis	SZ Gu, ME Ahmed, Y Huang, D Hakim, C Maynard, NV Cefalo, AU Coskun, C Costopoulos, A Maehara, GW Stone, PH Stone, MR Bennett	03/01/2024
Spatial Morphoproteomic Features Predict Uniqueness of Immune Microarchitectures and Responses in Lymphoid Follicles. bioRxiv : the preprint server for biology	T Hu, M Allam, V Kaushik, SL Goudy, Q Xu, P Mudd, K Manthiram, AF Coskun	01/07/2024
Single-cell spatial metabolomics with cell-type specific protein profiling for tissue systems biology. Nature communications	T Hu, M Allam, S Cai, W Henderson, B Yueh, A Garipcan, AV Ievlev, M Afkarian, S Beyaz, AF Coskun	12/13/2023
Single-cell RNA-sequencing and subcellular spatial transcriptomics facilitate the translation of liver microphysiological systems for regulatory application. Journal of pharmaceutical analysis	D Li, Z Fang, Q Shi, N Zhang, B Gong, W Tong, AF Coskun, J Xu	07/01/2023
Microbial Changes occurring during oronasal fistula wound healing. bioRxiv : the preprint server for biology	SL Goudy, H Bradley, CA Gacasan, A Toma, CR Naudin, WM Wuest, M Tomov, V Serpooshan, A Coskun, RM Jones	06/06/2023
Subcellular spatially resolved gene neighborhood networks in single cells. Cell reports methods	Z Fang, AJ Ford, T Hu, N Zhang, A Mantalaris, AF Coskun	05/22/2023
Combinatorial treatment rescues tumour-microenvironment-mediated attenuation of MALT1 inhibitors in B-cell lymphomas. Nature materials	SB Shah, CR Carlson, K Lai, Z Zhong, G Marsico, KM Lee, NE Félix Vélez, EB Abeles, M Allam, T Hu, LD Walter, KE Martin, K Gandhi, SD Butler, R Puri, AL McCleary-Wheeler, W Tam, O Elemento, K Takata, C Steidl, DW Scott, L Fontan, H Ueno, BD Cosgrove, G Inghirami, AJ García, AF Coskun, JL Koff, A Melnick, A Singh	04/01/2023
Spatial subcellular organelle networks in single cells. Scientific reports	M Venkatesan, N Zhang, B Marteau, Y Yajima, NO De Zarate Garcia, Z Fang, T Hu, S Cai, A Ford, H Olszewski, A Borst, AF Coskun	04/01/2023
Single-Cell and Spatial Analysis of Emergent Organoid Platforms. Methods in molecular biology (Clifton, N.J.)	A Kumar, S Cai, M Allam, S Henderson, M Ozbeyler, L Saiontz, AF Coskun	01/01/2023
Multiplexed protein profiling reveals spatial subcellular signaling networks. iScience	S Cai, T Hu, M Venkatesan, M Allam, F Schneider, SS Ramalingam, SY Sun, AF Coskun	09/16/2022
Spatially variant immune infiltration scoring in human cancer tissues. NPJ precision oncology	M Allam, T Hu, J Lee, J Aldrich, SS Badve, Y Gökmen-Polar, M Bhave, SS Ramalingam, F Schneider, AF Coskun	09/01/2022
Extracellular Matrix in Synthetic Hydrogel-Based Prostate Cancer Organoids Regulate Therapeutic Response to EZH2 and DRD2 Inhibitors. Advanced materials (Deerfield Beach, Fla.)	MJ Mosquera, S Kim, R Bareja, Z Fang, S Cai, H Pan, M Asad, ML Martin, M Sigouros, FM Rowdo, S Ackermann, J Capuano, J Bernheim, C Cheung, A Doane, N Brady, R Singh, DS Rickman, V Prabhu, JE Allen, L Puca, AF Coskun, MA Rubin, H Beltran, JM Mosquera, O Elemento, A Singh	01/01/2022
Subcellular localization of biomolecules and drug distribution by high-definition ion beam imaging. Nature communications	X Rovira-Clavé, S Jiang, Y Bai, B Zhu, G Barlow, S Bhate, AF Coskun, G Han, CK Ho, C Hitzman, SY Chen, FA Bava, GP Nolan	07/30/2021
Virtual and augmented reality for biomedical applications. Cell reports. Medicine	M Venkatesan, H Mohan, JR Ryan, CM Schürch, GP Nolan, DH Frakes, AF Coskun	07/20/2021
Spatially visualized single-cell pathology of highly multiplexed protein profiles in health and disease. Communications biology	M Allam, T Hu, S Cai, K Laxminarayanan, RB Hughley, AF Coskun	05/27/2021
Single-cell analysis reveals effective siRNA delivery in brain tumors with microbubble-enhanced ultrasound and cationic nanoparticles. Science advances	Y Guo, H Lee, Z Fang, A Velalopoulou, J Kim, MB Thomas, J Liu, RG Abramowitz, Y Kim, AF Coskun, DP Krummel, S Sengupta, TJ MacDonald, C Arvanitis	04/01/2021

Awards

Coskun is a recipient of the NSF CAREER Award 2024, NIH R35 MIRA Award 2023, Sigma Xi Young Faculty Award 2025, CMBE Young Innovator Award 2024, BMES-CMBE Rising Star Award 2023, American Lung Association Innovation Award 2022, Burroughs Welcome Fund CASI Award 2016, and Student Recognition of Excellence in Teaching: Class of 1934 CIOS Award, among other research and teaching awards.