Titles and Roles
- Professor and Chair in Cancer Biology, Department of Radiation Oncology
- Emory University School of Medicine
- Director of Discovery Theme, Discovery and Development Therapeutics Research Program
- Winship Cancer Institute of Emory University
- Research Program
- Discovery and Developmental Therapeutics
Xingming Deng, MD, PhD, is professor and the inaugural Chair in Cancer Biology in the Department of Radiation Oncology of Emory University School of Medicine. Dr. Deng is a faculty member engaged in cancer research. Prior to joining Emory in 2009, he was an assistant professor in the Division of Hematology/Oncology of the Department of Medicine at University of Florida.
Dr. Deng is an active member of the American Association for Cancer Research. He has been the recipient of eighteen research grants, including Clinical Innovator Awards from Flight Attendant Medical Research Institute, NASA research grant, and several R01 grants from NIH/NCI. He has served on several national and international grant review panels.
Dr. Deng teaches the advanced course for cancer biology to graduate students and medical residents. He has mentored a number of undergraduates, graduates, postdoctoral fellows, medical residents and junior faculty members at University of Florida and Emory University. He currently serves as a Course Director in Advanced Graduate Cancer Biology Program at Emory Laney Graduate School.
Dr. Deng received his MD/PhD at Hunan Medical University and Beijing Medical University in China. He completed his postdoctoral training in Molecular Biology at the University of Texas Medical Branch.
Dr. Deng's major research interests are to uncover cell death mechanisms, especially Bcl2 family, to investigate molecular and signaling mechanisms of DNA repair, DNA replication stress, genomic instability and carcinogenesis, to study signaling mechanisms of tumor invasion/metastasis, to develop novel small molecule anti-cancer agents and new therapeutic strategies for cancer therapy by targeting apoptosis and DNA repair signaling pathways, and to target novel signal mechanisms of PD-1 and PD-L1 for immunotherapy. Additionally, he is also studying environmental carcinogenesis, specifically mechanisms of tobacco smoke- or space radiation-induced DNA damage, genomic instability and carcinogenesis at the cellular, molecular and animal levels.
Deng has published many excellent research articles in high impact journals such as Molecular Cell, Cancer Cell, Nature Communications, The Journal of Clinical Investigation, PNAS, Cancer Research, Cell Death Differentiation, Nucleic Acid Research, MCB, Blood, and The Journal of Biological Chemistry among others. He serves on the editorial board for several journals and is frequently invited to serve as reviewer for numerous biomedical journals. He has also obtained three patents for new anticancer drug discovery.
Publications Publication Date
Dr. Deng has received a number of awards in his career including AACR-Bristol-Myers Squibb Young Investigator Award, three ASH Travel Awards, Basic Science Research Winner, Excellence in Research Award, Emory University Winship Scholar, and the Emory 1% Award with NIH R01 grant scoring in the top 1% at peer review.