Adam Gracz, PhD

Research Program

Cell and Molecular Biology
Phone Number

404-727-0616
Email Address

adam.gracz@emory.edu

Biography

Adam D. Gracz, PhD, is an assistant professor in the Division of Digestive Diseases in the Department of Medicine at Emory University School of Medicine in Atlanta, Georgia.

Dr. Gracz is a member of the Cell and Molecular Biology Research Program at Winship Cancer Institute. He is also a member of the Biochemistry, Cell and Developmental Biology, and Genetics and Molecular Biology graduate programs at Emory University.

Education

Dr. Gracz received his PhD and his Master of Science from University of North Carolina at Chapel Hill. He completed his postdoctoral training at University of Pennsylvania and at University of North Carolina at Chapel Hill.

Titles & Roles

Assistant Professor, Division of Digestive Diseases, Department of Medicine

Emory University School of Medicine

Research

Dr. Gracz's primary research interest is understanding how chromatin regulatory mechanisms establish and maintain cellular identity, especially in the context of regenerative biology. The current research objective of his lab is to understand transcriptional and chromatin regulation of epithelial biology in the intestine and intrahepatic bile ducts.

Publications

Title/Journal	Authors	Publication Date
Tritrichomonas muris sensitizes the intestinal epithelium to doxorubicin-induced apoptosis. American journal of physiology. Gastrointestinal and liver physiology	NV Janto, AR Gleizes, SJ Sun, G Ari, V Rao, AD Gracz	04/17/2025
Sox9 inhibits Activin A to promote biliary maturation and branching morphogenesis. Nature communications	HR Hrncir, B Goodloe, S Bombin, CB Hogan, O Jadi, AD Gracz	02/15/2025
Lgr5 + intestinal stem cells are required for organoid survival after genotoxic injury. Development (Cambridge, England)	J Lee, A Gleizes, NV Janto, LL Appell, S Sun, F Takaesu, SF Webster, T Hailstock, N Barker, AD Gracz	12/01/2024
Dietary fiber promotes antigen presentation on intestinal epithelial cells and development of small intestinal CD4⁺CD8αα⁺ intraepithelial T cells. Mucosal immunology	N Rodriguez-Marino, CJ Royer, DE Rivera-Rodriguez, E Seto, I Gracien, RM Jones, CD Scharer, AD Gracz, L Cervantes-Barragan	12/01/2024
Tritrichomonas muris sensitizes the intestinal epithelium to doxorubicin-induced apoptosis. bioRxiv : the preprint server for biology	NV Janto, AR Gleizes, S Sun, G Ari, AD Gracz	08/09/2024
Lgr5+ intestinal stem cells are required for organoid survival after genotoxic injury. bioRxiv : the preprint server for biology	J Lee, A Gleizes, F Takaesu, SF Webster, T Hailstock, N Barker, AD Gracz	04/25/2024
Tunable fluorescent probes for detecting aldehydes in living systems. Chemical science	R Wills, R Shirke, H Hrncir, JM Talbott, K Sad, JM Spangle, AD Gracz, M Raj	03/27/2024
Sox9 links biliary maturation to branching morphogenesis. bioRxiv : the preprint server for biology	HR Hrncir, S Bombin, B Goodloe, CB Hogan, O Jadi, AD Gracz	01/16/2024
Panic at the Bile Duct: How Intrahepatic Cholangiocytes Respond to Stress and Injury. The American journal of pathology	HR Hrncir, F Hantelys, AD Gracz	10/01/2023
SARS-CoV-2 Induces Epithelial-Enteric Neuronal Crosstalk Stimulating VIP Release. Biomolecules	A Balasubramaniam, PR Tedbury, SM Mwangi, Y Liu, G Li, D Merlin, AD Gracz, P He, SG Sarafianos, S Srinivasan	01/20/2023
Cellular and transcriptional heterogeneity in the intrahepatic biliary epithelium. Gastro hep advances	HR Hrncir, AD Gracz	01/01/2023