David Gutman, MD, PhD

Research Program

Discovery and Developmental Therapeutics
Phone Number

404-712-9206
Email Address

dgutman@emory.edu

Biography

David Gutman, MD, PhD is an associate professor in the Department of Biomedical Informatics at Emory University School of Medicine. Dr. Gutman joined the faculty at Emory in 2009. As a research scientist in the Center for Comprehensive Informatics (CCI), he is gaining expertise in whole slide digital imaging.

Dr. Gutman is a member of the Discovery and Developmental Therapeutics Research Program at Winship Cancer Institute.

Education

Dr. Gutman received his PhD in Neuroscience in 2005 and MD from Emory University in 2005. He completed his residency in Psychiatry at Emory University in 2009.

Titles & Roles

Associate Professor, Department of Biomedical Informatics

Emory University School of Medicine

Research

Broadly, Dr. Gutman is interested in using digital imaging technologies to answer important questions in neurosciences. Specifically, his work focuses on mining digital pathology and radiology imaging from glioma patients and correlating imaging based features with genetic and clinical variables. In addition, he maintains a strong interest in using DTI and MRI based techniques to understand neural circuitry.

Publications

Title/Journal	Authors	Publication Date
The association of azole antifungals with overall survival in patients with non-small cell lung cancer receiving immune checkpoint inhibitors. The oncologist	NT Sebastian, WA Stokes, M Behera, R Jiang, DA Gutman, Z Huang, A Burns, V Sukhatme, MC Lowe, SS Ramalingam, VP Sukhatme, D Moghanaki	09/25/2024
Summary of the National Cancer Institute 2023 Virtual Workshop on Medical Image De-identification-Part 2: Pathology Whole Slide Image De-identification, De-facing, the Role of AI in Image De-identification, and the NCI MIDI Datasets and Pipeline. Journal of imaging informatics in medicine	D Clunie, A Taylor, T Bisson, D Gutman, Y Xiao, CG Schwarz, D Greve, J Gichoya, G Shih, A Kline, B Kopchick, K Farahani	07/09/2024
Lung Cancer Survival Trends in the Veterans Health Administration. Clinical lung cancer	D Moghanaki, J Taylor, AK Bryant, LK Vitzthum, N Sebastian, D Gutman, A Burns, Z Huang, JA Lewis, LB Spalluto, CD Williams, DR Sullivan, CG Slatore, M Behera, WA Stokes	05/01/2024
Expert Agreement on the Presence and Spatial Localization of Melanocytic Features in Dermoscopy. The Journal of investigative dermatology	K Liopyris, C Navarrete-Dechent, MA Marchetti, V Rotemberg, Z Apalla, G Argenziano, A Blum, RP Braun, C Carrera, NCF Codella, M Combalia, SW Dusza, DA Gutman, B Helba, R Hofmann-Wellenhof, N Jaimes, H Kittler, K Kose, A Lallas, C Longo, J Malvehy, S Menzies, KC Nelson, J Paoli, S Puig, HS Rabinovitz, A Rishpon, T Russo, A Scope, HP Soyer, JA Stein, W Stolz, D Sgouros, AJ Stratigos, DL Swanson, L Thomas, P Tschandl, I Zalaudek, J Weber, AC Halpern, AA Marghoob	03/01/2024
A population-level digital histologic biomarker for enhanced prognosis of invasive breast cancer. Nature medicine	M Amgad, JM Hodge, MAT Elsebaie, C Bodelon, S Puvanesarajah, DA Gutman, KP Siziopikou, JA Goldstein, MM Gaudet, LR Teras, LAD Cooper	01/01/2024
Toward a generalizable machine learning workflow for neurodegenerative disease staging with focus on neurofibrillary tangles. Acta neuropathologica communications	JC Vizcarra, TM Pearce, BN Dugger, MJ Keiser, M Gearing, JF Crary, EJ Kiely, M Morris, B White, JD Glass, K Farrell, DA Gutman	12/18/2023
A population-level computational histologic signature for invasive breast cancer prognosis. Research square	M Amgad, J Hodge, M Elsebaie, C Bodelon, S Puvanesarajah, D Gutman, K Siziopikou, J Goldstein, M Gaudet, L Teras, L Cooper	05/26/2023
The Association of Improved Overall Survival with NSAIDs in Non-Small Cell Lung Cancer Patients Receiving Immune Checkpoint Inhibitors. Clinical lung cancer	NT Sebastian, WA Stokes, M Behera, R Jiang, DA Gutman, Z Huang, A Burns, V Sukhatme, MC Lowe, SS Ramalingam, VP Sukhatme, D Moghanaki	05/01/2023
Report of the Medical Image De-Identification (MIDI) Task Group - Best Practices and Recommendations. ArXiv	DA Clunie, A Flanders, A Taylor, B Erickson, B Bialecki, D Brundage, D Gutman, F Prior, JA Seibert, J Perry, JW Gichoya, J Kirby, K Andriole, L Geneslaw, S Moore, TJ Fitzgerald, W Tellis, Y Xiao, K Farahani, J Luo, A Rosenthal, K Kandarpa, R Rosen, K Goetz, D Babcock, B Xu, J Hsiao	04/01/2023
The status of digital pathology and associated infrastructure within Alzheimer's Disease Centers. Journal of neuropathology and experimental neurology	R Scalco, Y Hamsafar, CL White, JA Schneider, RR Reichard, S Prokop, RJ Perrin, PT Nelson, S Mooney, AP Lieberman, WA Kukull, J Kofler, CD Keene, A Kapasi, DJ Irwin, DA Gutman, ME Flanagan, JF Crary, KC Chan, ME Murray, BN Dugger	02/21/2023
An Automated Pipeline for Differential Cell Counts on Whole-Slide Bone Marrow Aspirate Smears. Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc	JE Lewis, CW Shebelut, BR Drumheller, X Zhang, N Shanmugam, M Attieh, MC Horwath, A Khanna, GH Smith, DA Gutman, A Aljudi, LAD Cooper, DL Jaye	02/01/2023
Impact of concomitant fibrates on immunotherapy outcomes for advanced non-small cell lung cancer. Cancer medicine	WA Stokes, M Behera, R Jiang, DA Gutman, Z Huang, A Burns, NT Sebastian, V Sukhatme, MC Lowe, SS Ramalingam, VP Sukhatme, D Moghanaki	01/01/2023
Survey of Neuroanatomic Sampling and Staining Procedures in Alzheimer Disease Research Center Brain Banks. Free neuropathology	JC Vizcarra, AF Teich, BN Dugger, DA Gutman	01/01/2023
NuCLS: A scalable crowdsourcing approach and dataset for nucleus classification and segmentation in breast cancer. GigaScience	M Amgad, LA Atteya, H Hussein, KH Mohammed, E Hafiz, MAT Elsebaie, AM Alhusseiny, MA AlMoslemany, AM Elmatboly, PA Pappalardo, RA Sakr, P Mobadersany, A Rachid, AM Saad, AM Alkashash, IA Ruhban, A Alrefai, NM Elgazar, A Abdulkarim, AA Farag, A Etman, AG Elsaeed, Y Alagha, YA Amer, AM Raslan, MK Nadim, MAT Elsebaie, A Ayad, LE Hanna, A Gadallah, M Elkady, B Drumheller, D Jaye, D Manthey, DA Gutman, H Elfandy, LAD Cooper	05/17/2022
MITI minimum information guidelines for highly multiplexed tissue images. Nature methods	D Schapiro, C Yapp, A Sokolov, SM Reynolds, YA Chen, D Sudar, Y Xie, J Muhlich, R Arias-Camison, S Arena, AJ Taylor, M Nikolov, M Tyler, JR Lin, EA Burlingame, YH Chang, SL Farhi, V Thorsson, N Venkatamohan, JL Drewes, D Pe'er, DA Gutman, MD Herrmann, N Gehlenborg, P Bankhead, JT Roland, JM Herndon, MP Snyder, M Angelo, G Nolan, JR Swedlow, N Schultz, DT Merrick, SA Mazzili, E Cerami, SJ Rodig, S Santagata, PK Sorger	03/01/2022
Explainable nucleus classification using Decision Tree Approximation of Learned Embeddings. Bioinformatics (Oxford, England)	M Amgad, LA Atteya, H Hussein, KH Mohammed, E Hafiz, MAT Elsebaie, P Mobadersany, D Manthey, DA Gutman, H Elfandy, LAD Cooper	01/03/2022
Checklist for Evaluation of Image-Based Artificial Intelligence Reports in Dermatology: CLEAR Derm Consensus Guidelines From the International Skin Imaging Collaboration Artificial Intelligence Working Group. JAMA dermatology	R Daneshjou, C Barata, B Betz-Stablein, ME Celebi, N Codella, M Combalia, P Guitera, D Gutman, A Halpern, B Helba, H Kittler, K Kose, K Liopyris, J Malvehy, HS Seog, HP Soyer, ER Tkaczyk, P Tschandl, V Rotemberg	01/01/2022
Neuromorphological Changes following Selection for Tameness and Aggression in the Russian Farm-Fox experiment. The Journal of neuroscience : the official journal of the Society for Neuroscience	EE Hecht, AV Kukekova, DA Gutman, GM Acland, TM Preuss, LN Trut	07/14/2021
Image Analysis Pipeline for Renal Allograft Evaluation and Fibrosis Quantification. Kidney international reports	AB Farris, J Vizcarra, M Amgad, LA Donald Cooper, D Gutman, J Hogan	07/01/2021
Artificial intelligence and algorithmic computational pathology: an introduction with renal allograft examples. Histopathology	AB Farris, J Vizcarra, M Amgad, LAD Cooper, D Gutman, J Hogan	05/01/2021
Interactive Classification of Whole-Slide Imaging Data for Cancer Researchers. Cancer research	S Lee, M Amgad, P Mobadersany, M McCormick, BP Pollack, H Elfandy, H Hussein, DA Gutman, LAD Cooper	02/15/2021
A patient-centric dataset of images and metadata for identifying melanomas using clinical context. Scientific data	V Rotemberg, N Kurtansky, B Betz-Stablein, L Caffery, E Chousakos, N Codella, M Combalia, S Dusza, P Guitera, D Gutman, A Halpern, B Helba, H Kittler, K Kose, S Langer, K Lioprys, J Malvehy, S Musthaq, J Nanda, O Reiter, G Shih, A Stratigos, P Tschandl, J Weber, HP Soyer	01/28/2021
Integrating Eye Tracking and Speech Recognition Accurately Annotates MR Brain Images for Deep Learning: Proof of Principle. Radiology. Artificial intelligence	JN Stember, H Celik, D Gutman, N Swinburne, R Young, S Eskreis-Winkler, A Holodny, S Jambawalikar, BJ Wood, PD Chang, E Krupinski, U Bagci	01/01/2021
Validation of machine learning models to detect amyloid pathologies across institutions. Acta neuropathologica communications	JC Vizcarra, M Gearing, MJ Keiser, JD Glass, BN Dugger, DA Gutman	04/28/2020
Computer algorithms show potential for improving dermatologists' accuracy to diagnose cutaneous melanoma: Results of the International Skin Imaging Collaboration 2017. Journal of the American Academy of Dermatology	MA Marchetti, K Liopyris, SW Dusza, NCF Codella, DA Gutman, B Helba, A Kalloo, AC Halpern	03/01/2020
Radiomics Features Predict CIC Mutation Status in Lower Grade Glioma. Frontiers in oncology	L Zhang, F Giuste, JC Vizcarra, X Li, D Gutman	01/01/2020
Machine-based detection and classification for bone marrow aspirate differential counts: initial development focusing on nonneoplastic cells. Laboratory investigation; a journal of technical methods and pathology	R Chandradevan, AA Aljudi, BR Drumheller, N Kunananthaseelan, M Amgad, DA Gutman, LAD Cooper, DL Jaye	01/01/2020
Phosphoinositide 3-Kinase Signaling Can Modulate MHC Class I and II Expression. Molecular cancer research : MCR	S Chandrasekaran, M Sasaki, CD Scharer, HT Kissick, DG Patterson, KR Magliocca, JT Seykora, B Sapkota, DA Gutman, LA Cooper, GB Lesinski, EK Waller, SN Thomas, SV Kotenko, JM Boss, CS Moreno, RA Swerlick, BP Pollack	12/01/2019
Structured crowdsourcing enables convolutional segmentation of histology images. Bioinformatics (Oxford, England)	M Amgad, H Elfandy, H Hussein, LA Atteya, MAT Elsebaie, LS Abo Elnasr, RA Sakr, HSE Salem, AF Ismail, AM Saad, J Ahmed, MAT Elsebaie, M Rahman, IA Ruhban, NM Elgazar, Y Alagha, MH Osman, AM Alhusseiny, MM Khalaf, AF Younes, A Abdulkarim, DM Younes, AM Gadallah, AM Elkashash, SY Fala, BM Zaki, J Beezley, DR Chittajallu, D Manthey, DA Gutman, LAD Cooper	09/15/2019
Fusion in Breast Cancer Histology Classification. ACM-BCB ... ... : the ... ACM Conference on Bioinformatics, Computational Biology and Biomedicine. ACM Conference on Bioinformatics, Computational Biology and Biomedicine	J Vizcarra, R Place, L Tong, D Gutman, MD Wang	09/01/2019
Comparison of the accuracy of human readers versus machine-learning algorithms for pigmented skin lesion classification: an open, web-based, international, diagnostic study. The Lancet. Oncology	P Tschandl, N Codella, BN Akay, G Argenziano, RP Braun, H Cabo, D Gutman, A Halpern, B Helba, R Hofmann-Wellenhof, A Lallas, J Lapins, C Longo, J Malvehy, MA Marchetti, A Marghoob, S Menzies, A Oakley, J Paoli, S Puig, C Rinner, C Rosendahl, A Scope, C Sinz, HP Soyer, L Thomas, I Zalaudek, H Kittler	07/01/2019
TDP-43 cytoplasmic inclusion formation is disrupted in C9orf72-associated amyotrophic lateral sclerosis/frontotemporal lobar degeneration. Brain communications	SM Lee, S Asress, CM Hales, M Gearing, JC Vizcarra, CN Fournier, DA Gutman, LS Chin, L Li, JD Glass	01/01/2019
Diagnostic accuracy of whole slide imaging for cutaneous, soft tissue, and melanoma sentinel lymph node biopsies with and without immunohistochemistry. Journal of cutaneous pathology	MR Sargen, KM Luk, BK Stoff, J MacKelfresh, S Patrawala, C Zhang, D Gutman, SC Chen	08/01/2018
Predicting cancer outcomes from histology and genomics using convolutional networks. Proceedings of the National Academy of Sciences of the United States of America	P Mobadersany, S Yousefi, M Amgad, DA Gutman, JS Barnholtz-Sloan, JE Velázquez Vega, DJ Brat, LAD Cooper	03/27/2018
Results of the 2016 International Skin Imaging Collaboration International Symposium on Biomedical Imaging challenge: Comparison of the accuracy of computer algorithms to dermatologists for the diagnosis of melanoma from dermoscopic images. Journal of the American Academy of Dermatology	MA Marchetti, NCF Codella, SW Dusza, DA Gutman, B Helba, A Kalloo, N Mishra, C Carrera, ME Celebi, JL DeFazio, N Jaimes, AA Marghoob, E Quigley, A Scope, O Yélamos, AC Halpern	02/01/2018
5-Aminolevulinic Acid Guided Sampling of Glioblastoma Microenvironments Identifies Pro-Survival Signaling at Infiltrative Margins. Scientific reports	JL Ross, LAD Cooper, J Kong, D Gutman, M Williams, C Tucker-Burden, MR McCrary, A Bouras, M Kaluzova, WD Dunn, D Duong, CG Hadjipanayis, DJ Brat	11/15/2017
Interactive phenotyping of large-scale histology imaging data with HistomicsML. Scientific reports	M Nalisnik, M Amgad, S Lee, SH Halani, JE Velazquez Vega, DJ Brat, DA Gutman, LAD Cooper	11/06/2017
The Digital Slide Archive: A Software Platform for Management, Integration, and Analysis of Histology for Cancer Research. Cancer research	DA Gutman, M Khalilia, S Lee, M Nalisnik, Z Mullen, J Beezley, DR Chittajallu, D Manthey, LAD Cooper	11/01/2017
Predicting clinical outcomes from large scale cancer genomic profiles with deep survival models. Scientific reports	S Yousefi, F Amrollahi, M Amgad, C Dong, JE Lewis, C Song, DA Gutman, SH Halani, JE Velazquez Vega, DJ Brat, LAD Cooper	09/15/2017
The molecular basis of breast cancer pathological phenotypes. The Journal of pathology	YJ Heng, SC Lester, GM Tse, RE Factor, KH Allison, LC Collins, YY Chen, KC Jensen, NB Johnson, JC Jeong, R Punjabi, SJ Shin, K Singh, G Krings, DA Eberhard, PH Tan, K Korski, FM Waldman, DA Gutman, M Sanders, JS Reis-Filho, SR Flanagan, DM Gendoo, GM Chen, B Haibe-Kains, G Ciriello, KA Hoadley, CM Perou, AH Beck	02/01/2017
REDLetr: Workflow and tools to support the migration of legacy clinical data capture systems to REDCap. International journal of medical informatics	WD Dunn, J Cobb, AI Levey, DA Gutman	09/01/2016
Imaging-genomics reveals driving pathways of MRI derived volumetric tumor phenotype features in Glioblastoma. BMC cancer	P Grossmann, DA Gutman, WD Dunn, CA Holder, HJ Aerts	08/08/2016
Applicability of digital analysis and imaging technology in neuropathology assessment. Neuropathology : official journal of the Japanese Society of Neuropathology	WD Dunn, M Gearing, Y Park, L Zhang, J Hanfelt, JD Glass, DA Gutman	06/01/2016
Gene integrated set profile analysis: a context-based approach for inferring biological endpoints. Nucleic acids research	J Kowalski, B Dwivedi, S Newman, JM Switchenko, R Pauly, DA Gutman, J Arora, K Gandhi, K Ainslie, G Doho, Z Qin, CS Moreno, MR Rossi, PM Vertino, S Lonial, L Bernal-Mizrachi, LH Boise	04/20/2016
A combinatorial radiographic phenotype may stratify patient survival and be associated with invasion and proliferation characteristics in glioblastoma. Journal of neurosurgery	A Rao, G Rao, DA Gutman, AE Flanders, SN Hwang, DL Rubin, RR Colen, PO Zinn, R Jain, M Wintermark, JS Kirby, CC Jaffe, J Freymann	04/01/2016
A Symmetry-Based Method to Infer Structural Brain Networks from Probabilistic Tractography Data. Frontiers in neuroinformatics	K Shadi, S Bakhshi, DA Gutman, HS Mayberg, C Dovrolis	01/01/2016
Assessing the Effects of Software Platforms on Volumetric Segmentation of Glioblastoma. Journal of neuroimaging in psychiatry & neurology	WD Dunn, HJWL Aerts, LA Cooper, CA Holder, SN Hwang, CC Jaffe, DJ Brat, R Jain, AE Flanders, PO Zinn, RR Colen, DA Gutman	01/01/2016
Somatic mutations associated with MRI-derived volumetric features in glioblastoma. Neuroradiology	DA Gutman, WD Dunn, P Grossmann, LA Cooper, CA Holder, KL Ligon, BM Alexander, HJ Aerts	12/01/2015
Fully automatic GBM segmentation in the TCGA-GBM dataset: Prognosis and correlation with VASARI features. Scientific reports	E Rios Velazquez, R Meier, WD Dunn, B Alexander, R Wiest, S Bauer, DA Gutman, M Reyes, HJ Aerts	11/18/2015
Organization of intrinsic functional brain connectivity predicts decisions to reciprocate social behavior. Behavioural brain research	R Cáceda, GA James, DA Gutman, CD Kilts	10/01/2015
Acquisition of Paleolithic toolmaking abilities involves structural remodeling to inferior frontoparietal regions. Brain structure & function	EE Hecht, DA Gutman, N Khreisheh, SV Taylor, J Kilner, AA Faisal, BA Bradley, T Chaminade, D Stout	07/01/2015
Addition of MR imaging features and genetic biomarkers strengthens glioblastoma survival prediction in TCGA patients. Journal of neuroradiology = Journal de neuroradiologie	M Nicolasjilwan, Y Hu, C Yan, D Meerzaman, CA Holder, D Gutman, R Jain, R Colen, DL Rubin, PO Zinn, SN Hwang, P Raghavan, DA Hammoud, LM Scarpace, T Mikkelsen, J Chen, O Gevaert, K Buetow, J Freymann, J Kirby, AE Flanders, M Wintermark	07/01/2015
Novel genotype-phenotype associations in human cancers enabled by advanced molecular platforms and computational analysis of whole slide images. Laboratory investigation; a journal of technical methods and pathology	LA Cooper, J Kong, DA Gutman, WD Dunn, M Nalisnik, DJ Brat	04/01/2015
Glioblastoma: imaging genomic mapping reveals sex-specific oncogenic associations of cell death. Radiology	RR Colen, J Wang, SK Singh, DA Gutman, PO Zinn	04/01/2015
Virtual dissection and comparative connectivity of the superior longitudinal fasciculus in chimpanzees and humans. NeuroImage	EE Hecht, DA Gutman, BA Bradley, TM Preuss, D Stout	03/01/2015
A comparative analysis of mouse and human medial geniculate nucleus connectivity: a DTI and anterograde tracing study. NeuroImage	OP Keifer, DA Gutman, EE Hecht, SD Keilholz, KJ Ressler	01/15/2015
An Interactive Learning Framework for Scalable Classification of Pathology Images. Proceedings : ... IEEE International Conference on Big Data. IEEE International Conference on Big Data	M Nalisnik, DA Gutman, J Kong, LA Cooper	01/01/2015
Social subordination stress and serotonin transporter polymorphisms: associations with brain white matter tract integrity and behavior in juvenile female macaques. Cerebral cortex (New York, N.Y. : 1991)	BR Howell, J Godfrey, DA Gutman, V Michopoulos, X Zhang, G Nair, X Hu, ME Wilson, MM Sanchez	12/01/2014
NCI Workshop Report: Clinical and Computational Requirements for Correlating Imaging Phenotypes with Genomics Signatures. Translational oncology	R Colen, I Foster, R Gatenby, ME Giger, R Gillies, D Gutman, M Heller, R Jain, A Madabhushi, S Madhavan, S Napel, A Rao, J Saltz, J Tatum, R Verhaak, G Whitman	10/01/2014
Outcome prediction in patients with glioblastoma by using imaging, clinical, and genomic biomarkers: focus on the nonenhancing component of the tumor. Radiology	R Jain, LM Poisson, D Gutman, L Scarpace, SN Hwang, CA Holder, M Wintermark, A Rao, RR Colen, J Kirby, J Freymann, CC Jaffe, T Mikkelsen, A Flanders	08/01/2014
PACAP receptor gene polymorphism impacts fear responses in the amygdala and hippocampus. Proceedings of the National Academy of Sciences of the United States of America	JS Stevens, LM Almli, N Fani, DA Gutman, B Bradley, SD Norrholm, E Reiser, TD Ely, R Dhanani, EM Glover, T Jovanovic, KJ Ressler	02/25/2014
Microembolism induces anhedonia but no detectable changes in white matter integrity in aged rats. PloS one	CL Nemeth, DA Gutman, W Majeed, SD Keilholz, GN Neigh	01/01/2014
Tumor-infiltrating lymphocytes in glioblastoma are associated with specific genomic alterations and related to transcriptional class. Clinical cancer research : an official journal of the American Association for Cancer Research	WC Rutledge, J Kong, J Gao, DA Gutman, LA Cooper, C Appin, Y Park, L Scarpace, T Mikkelsen, ML Cohen, KD Aldape, RE McLendon, NL Lehman, CR Miller, MJ Schniederjan, CW Brennan, JH Saltz, CS Moreno, DJ Brat	09/15/2013
Differences in neural activation for object-directed grasping in chimpanzees and humans. The Journal of neuroscience : the official journal of the Society for Neuroscience	EE Hecht, LE Murphy, DA Gutman, JR Votaw, DM Schuster, TM Preuss, GA Orban, D Stout, LA Parr	08/28/2013
Process versus product in social learning: comparative diffusion tensor imaging of neural systems for action execution-observation matching in macaques, chimpanzees, and humans. Cerebral cortex (New York, N.Y. : 1991)	EE Hecht, DA Gutman, TM Preuss, MM Sanchez, LA Parr, JK Rilling	05/01/2013
MR imaging predictors of molecular profile and survival: multi-institutional study of the TCGA glioblastoma data set. Radiology	DA Gutman, LA Cooper, SN Hwang, CA Holder, J Gao, TD Aurora, WD Dunn, L Scarpace, T Mikkelsen, R Jain, M Wintermark, M Jilwan, P Raghavan, E Huang, RJ Clifford, P Mongkolwat, V Kleper, J Freymann, J Kirby, PO Zinn, CS Moreno, C Jaffe, R Colen, DL Rubin, J Saltz, A Flanders, DJ Brat	05/01/2013
FKBP5 and attention bias for threat: associations with hippocampal function and shape. JAMA psychiatry	N Fani, D Gutman, EB Tone, L Almli, KB Mercer, J Davis, E Glover, T Jovanovic, B Bradley, ID Dinov, A Zamanyan, AW Toga, EB Binder, KJ Ressler	04/01/2013
Genomic mapping and survival prediction in glioblastoma: molecular subclassification strengthened by hemodynamic imaging biomarkers. Radiology	R Jain, L Poisson, J Narang, D Gutman, L Scarpace, SN Hwang, C Holder, M Wintermark, RR Colen, J Kirby, J Freymann, DJ Brat, C Jaffe, T Mikkelsen	04/01/2013
Mapping of the mouse olfactory system with manganese-enhanced magnetic resonance imaging and diffusion tensor imaging. Brain structure & function	DA Gutman, M Magnuson, W Majeed, OP Keifer, M Davis, KJ Ressler, S Keilholz	03/01/2013
Cancer Digital Slide Archive: an informatics resource to support integrated in silico analysis of TCGA pathology data. Journal of the American Medical Informatics Association : JAMIA	DA Gutman, J Cobb, D Somanna, Y Park, F Wang, T Kurc, JH Saltz, DJ Brat, LA Cooper	01/01/2013
A DTI tractography analysis of infralimbic and prelimbic connectivity in the mouse using high-throughput MRI. NeuroImage	DA Gutman, OP Keifer, ME Magnuson, DC Choi, W Majeed, S Keilholz, KJ Ressler	11/01/2012
White matter integrity in highly traumatized adults with and without post-traumatic stress disorder. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology	N Fani, TZ King, T Jovanovic, EM Glover, B Bradley, K Choi, T Ely, DA Gutman, KJ Ressler	11/01/2012
Neural correlates of attention bias to threat in post-traumatic stress disorder. Biological psychology	N Fani, T Jovanovic, TD Ely, B Bradley, D Gutman, EB Tone, KJ Ressler	05/01/2012
The tumor microenvironment strongly impacts master transcriptional regulators and gene expression class of glioblastoma. The American journal of pathology	LA Cooper, DA Gutman, C Chisolm, C Appin, J Kong, Y Rong, T Kurc, EG Van Meir, JH Saltz, CS Moreno, DJ Brat	05/01/2012
Digital Pathology: Data-Intensive Frontier in Medical Imaging: Health-information sharing, specifically of digital pathology, is the subject of this paper which discusses how sharing the rich images in pathology can stretch the capabilities of all otherwise well-practiced disciplines. Proceedings of the IEEE. Institute of Electrical and Electronics Engineers	LA Cooper, AB Carter, AB Farris, F Wang, J Kong, DA Gutman, P Widener, TC Pan, SR Cholleti, A Sharma, TM Kurc, DJ Brat, JH Saltz	04/01/2012
Integrated morphologic analysis for the identification and characterization of disease subtypes. Journal of the American Medical Informatics Association : JAMIA	LA Cooper, J Kong, DA Gutman, F Wang, J Gao, C Appin, S Cholleti, T Pan, A Sharma, L Scarpace, T Mikkelsen, T Kurc, CS Moreno, DJ Brat, JH Saltz	01/01/2012
Integrative, multimodal analysis of glioblastoma using TCGA molecular data, pathology images, and clinical outcomes. IEEE transactions on bio-medical engineering	J Kong, LA Cooper, F Wang, DA Gutman, J Gao, C Chisolm, A Sharma, T Pan, EG Van Meir, TM Kurc, CS Moreno, JH Saltz, DJ Brat	12/01/2011
Persistent anxiolytic affects after chronic administration of the CRF₁ receptor antagonist R121919 in rats. Neuropharmacology	DA Gutman, MJ Owens, KV Thrivikraman, CB Nemeroff	06/01/2011
An informatics framework for testing data integrity and correctness of federated biomedical databases. AMIA Joint Summits on Translational Science proceedings. AMIA Joint Summits on Translational Science	M Kim, T Kurc, A Orso, J Cobb, D Gutman, MJ Harrold, A Post, A Sharma, J Saltz	01/01/2011
An integrative approach for in silico glioma research. IEEE transactions on bio-medical engineering	LA Cooper, J Kong, DA Gutman, F Wang, SR Cholleti, TC Pan, PM Widener, A Sharma, T Mikkelsen, AE Flanders, DL Rubin, EG Van Meir, TM Kurc, CS Moreno, DJ Brat, JH Saltz	10/01/2010
The proneural molecular signature is enriched in oligodendrogliomas and predicts improved survival among diffuse gliomas. PloS one	LA Cooper, DA Gutman, Q Long, BA Johnson, SR Cholleti, T Kurc, JH Saltz, DJ Brat, CS Moreno	09/03/2010
A tractography analysis of two deep brain stimulation white matter targets for depression. Biological psychiatry	DA Gutman, PE Holtzheimer, TE Behrens, H Johansen-Berg, HS Mayberg	02/15/2009
Behavioral effects of the CRF1 receptor antagonist R121919 in rats selectively bred for high and low activity in the swim test. Psychoneuroendocrinology	DA Gutman, MJ Coyer, KA Boss-Williams, MJ Owens, CB Nemeroff, JM Weiss	09/01/2008

Awards

In 2015, Dr. Gutman and his colleague, Lee Cooper, PhD, received a $3.5 million Informatics Technology for Cancer Research (ITCR) U24 award from the National Cancer Institute, a five-year award to develop software tools to help researchers gain new insights from cancer imaging data. Learn more.