Stefan Kaluz, PhD

P9989534

Titles and Roles

Instructor, Department of Neurosurgery
Emory University School of Medicine
Research Program
Cancer Cell Biology

Biography

Stefan Kaluz, PhD, serves as Instructor in the Department of Neurosurgery at Emory University School of Medicine. Dr. Kaluz is a member of the Cancer Cell Biology Research Program at Winship.

Education

Dr. Kaluz earned his PhD in Chemistry from Comenius University in Czechoslovakia. He then completed postdoctoral programs in Molecular Biology at Slovak Academy of Sciences, also in Czechoslovakia, and the University of Nottingham in the UK.

Research

Dr. Kaluz's research interests focus on understanding the development of hypoxia in solid tumors, its molecular sequelae, and how to devise new diagnostics and therapeutics that will ultimately improve patient survival. He examines how hypoxia and genetic alterations induce changes in expression patterns and the role of products of the hypoxia-inducible genes in promoting tumor progression, especially those coding for pH regulating enzymes, growth factors, and angiogenic factors.

Dr. Kaluz also works to develop novel therapeutic approaches for cancer based on small molecule inhibitors of the hypoxia-inducible factor (HIF) pathway. His interest is to understand the determinants that make tumors sensitive to these inhibitors, translate these novel agents to testing in clinical trials with the hope to develop novel medicines for cancer treatment. 

Publications

Dr. Kaluz is on the international editorial board of the journal Acta Virologica.

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