Subra Kugathasan, MD

Research Program

Cancer Prevention and Control
Phone Number

404-727-4542
Email Address

skugath@emory.edu

Biography

Subra Kugathasan, MD, is a professor in the Departments of Pediatrics and Human Genetics at Emory University School of Medicine. Dr. Kugathasan also serves as scientific director of Children's Healthcare of Atlanta Combined Center for Pediatric Inflammatory Bowel Disease. He is a member of the Cancer Prevention and Control Research Program at Winship.

Education

Dr. Kugathasan earned his MD from Jaffna Hindu College in Sri Lanka. After obtaining his MD, Dr. Kugathasan completed his residency at Sinai Hospital of Baltimore, fellowship at Rainbow Babies and Children's Hospital in Cleveland, and internship at University Hospital of Wales.

Titles & Roles

Professor, Department of Pediatrics

Emory University School of Medicine
Professor, Department of Human Genetics

Emory University School of Medicine
Scientific Director, Children's Healthcare of Atlanta Combined Center for Pediatric Inflammatory Bowel Disease

Children's Healthcare of Atlanta

Professional Memberships

Dr. Kugathasan is a member of the American Gastroenterology Association, Crohn's and Colitis Foundation of America, North American Society for Pediatric Gastroenterology, Hepatology and Nutrition, and Royal College of Physicians.

Research

Dr. Kugathasan's research goal is to further extend novel genetic discoveries in inflammatory bowel disease, in particular common and rare susceptibility variants that are the cause of very early onset of the disease. In addition, he has been investigating the immunogenetic mechanisms that underlie this chronic intestinal inflammation in children and adults.

>>Visit Kugathasan Laboratory.

Grants

View Grants

Grant Number	Title
5R01DK087694-13	Gene discoveries in subjects with Crohn's disease of African descent
5T32DK108735-07	Research Training in Translational Gastroenterology and Hepatology
5T32DK108735-08	Research Training in Translational Gastroenterology and Hepatology

Publications

Title/Journal	Authors	Publication Date
1000-plex antibody array proteomic screen uncovers PGRPS, Haptoglobin, Serpin A4 and Fibrinogen as potential stool biomarkers of pediatric inflammatory bowel disease. Clinical immunology (Orlando, Fla.)	R Pereira, S Soomro, K Vanarsa, J Castillo, V Maruvada, S Kugathasan, C Mohan	07/01/2025
Circulating and Magnetic Resonance Imaging Biomarkers of Intestinal Fibrosis in Small Bowel Crohn's Disease. Inflammatory bowel diseases	JR Dillman, JA Tkach, JG Fletcher, DH Bruining, A Lu, S Kugathasan, AL Alazraki, J Knight-Scott, RW Stidham, J Adler, P Minar, BC Trapnell, EL Bonkowski, H Jurrell, O Lopez-Nunez, MH Collins, SD Swanson, L Fei, L Qian, AJ Towbin, M Kocaoglu, CG Anton, RA Imbus, JA Dudley, LA Denson	05/12/2025
Altered inflammatory mucosal signatures within their spatial and cellular context during active ileal Crohn's disease. JCI insight	VL Kolachala, SC Maddipatla, S Murthy, Y Hwang, AF Dodd, G Sharma, S Munasinghe, RS Pelia, S Venkateswaran, M Anbazhagan, T Koti, N Jhita, GN Joshi, CA Lopez, D Geem, H Yin, DJ Cutler, P Qiu, JD Matthews, S Kugathasan	03/10/2025
Eleven Grand Challenges for Inflammatory Bowel Disease Genetics and Genomics. Inflammatory bowel diseases	G Gibson, JD Rioux, JH Cho, T Haritunians, A Thoutam, MT Abreu, SR Brant, S Kugathasan, JL McCauley, M Silverberg, D McGovern	01/06/2025
Crohn's Patients and Healthy Infants Share Immunodominant B Cell Response to Commensal Flagellin Peptide Epitopes. Gastroenterology	Q Zhao, LW Duck, JT Killian, AF Rosenberg, PJ Mannon, RG King, LA Denson, S Kugathasan, EN Janoff, MC Jenmalm, CO Elson	12/01/2024
MRI and Blood-based Biomarkers Are Associated With Surgery in Children and Adults With Ileal Crohn's Disease. Inflammatory bowel diseases	JR Dillman, JA Tkach, JG Fletcher, DH Bruining, A Lu, S Kugathasan, AL Alazraki, J Knight-Scott, RW Stidham, J Adler, BC Trapnell, SD Swanson, L Fei, L Qian, AJ Towbin, M Kocaoglu, CG Anton, RA Imbus, JA Dudley, LA Denson	11/04/2024
Single-cell transcriptomics of rectal organoids from individuals with perianal fistulizing Crohn's disease reveals patient-specific signatures. Scientific reports	S Murthy, M Anbazhagan, SC Maddipatla, VL Kolachala, A Dodd, R Pelia, DJ Cutler, JD Matthews, S Kugathasan	10/30/2024
PTGER4 signaling regulates class IIa HDAC function and SPINK4 mRNA levels in rectal epithelial cells. Cell communication and signaling : CCS	M Anbazhagan, G Sharma, S Murthy, SC Maddipatla, VL Kolachala, A Dodd, A Randunne, DJ Cutler, S Kugathasan, JD Matthews	10/13/2024
Patient-derived organoid biobank identifies epigenetic dysregulation of intestinal epithelial MHC-I as a novel mechanism in severe Crohn's Disease. Gut	TW Dennison, RD Edgar, F Payne, KM Nayak, ADB Ross, A Cenier, C Glemas, F Giachero, AR Foster, R Harris, J Kraiczy, C Salvestrini, G Stavrou, F Torrente, K Brook, C Trayers, R Elmentaite, G Youssef, B Tél, DJ Winton, N Skoufou-Papoutsaki, S Adler, P Bufler, A Azabdaftari, A Jenke, N G, N Thomas, E Miele, A Al-Mohammad, G Guarda, S Kugathasan, S Venkateswaran, MR Clatworthy, T Castro-Dopico, O Suchanek, C Strisciuglio, M Gasparetto, S Lee, X Xu, E Bello, N Han, DR Zerbino, SA Teichmann, J Nys, R Heuschkel, F Perrone, M Zilbauer	08/08/2024
Vascular endothelial growth factor secretion and immunosuppression are distinct potency mechanisms of human bone marrow mesenchymal stromal cells. Stem cells (Dayton, Ohio)	TU Faircloth, S Temple, RN Parr, AB Tucker, D Rajan, P Hematti, S Kugathasan, R Chinnadurai	08/01/2024
Comprehensive Association Analyses of Extraintestinal Manifestations in Inflammatory Bowel Disease. Gastroenterology	M Khrom, M Long, S Dube, L Robbins, GJ Botwin, S Yang, E Mengesha, D Li, T Naito, NN Bonthala, C Ha, G Melmed, S Rabizadeh, G Syal, E Vasiliauskas, D Ziring, SR Brant, J Cho, RH Duerr, J Rioux, P Schumm, M Silverberg, AN Ananthakrishnan, WA Faubion, B Jabri, SA Lira, RD Newberry, RS Sandler, RJ Xavier, S Kugathasan, D Hercules, SR Targan, RB Sartor, T Haritunians, DPB McGovern	07/01/2024
An isoform quantitative trait locus in SBNO2 links genetic susceptibility to Crohn's disease with defective antimicrobial activity. Nature communications	D Aschenbrenner, I Nassiri, S Venkateswaran, S Pandey, M Page, L Drowley, M Armstrong, S Kugathasan, B Fairfax, HH Uhlig	05/28/2024
Concordant B and T Cell Heterogeneity Inferred from the Multiomic Landscape of Peripheral Blood Mononuclear Cells in a Crohn's Disease Cohort. Journal of Crohn's & colitis	M Brown, A Dodd, F Shi, E Greenwood, S Nagpal, VL Kolachala, S Kugathasan, G Gibson	04/13/2024
Linking microbial genes to plasma and stool metabolites uncovers host-microbial interactions underlying ulcerative colitis disease course. Cell host & microbe	M Schirmer, M Stražar, J Avila-Pacheco, DF Rojas-Tapias, EM Brown, E Temple, A Deik, K Bullock, S Jeanfavre, K Pierce, S Jin, R Invernizzi, MM Pust, Z Costliow, DR Mack, AM Griffiths, T Walters, BM Boyle, S Kugathasan, H Vlamakis, J Hyams, L Denson, CB Clish, RJ Xavier	02/14/2024
Progression of Pediatric Crohn's Disease Is Associated With Anti-Tumor Necrosis Factor Timing and Body Mass Index Z-Score Normalization. Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association	D Geem, D Hercules, RS Pelia, S Venkateswaran, A Griffiths, JD Noe, JL Dotson, S Snapper, S Rabizadeh, JR Rosh, RN Baldassano, JF Markowitz, TD Walters, A Ananthakrishnan, G Sharma, LA Denson, JS Hyams, S Kugathasan	02/01/2024
Cell Spatial Analysis in Crohn's Disease: Unveiling Local Cell Arrangement Pattern with Graph-based Signatures. Proceedings of SPIE--the International Society for Optical Engineering	S Bao, S Zhu, VL Kolachala, LW Remedios, Y Hwang, Y Sun, R Deng, C Cui, R Zhang, Y Li, J Li, JT Roland, Q Liu, KS Lau, S Kugathasan, P Qiu, KT Wilson, LA Coburn, BA Landman, Y Huo	02/01/2024
Persistent Inflammation of the Rectum in Perianal Fistulizing Crohn's Disease Is Associated With Goblet Cell Function. Gastro hep advances	S Washburn, SC Maddipatla, S Murthy, A Dodd, RS Pelia, VL Kolachala, D Geem, JD Matthews, G Gibson, S Kugathasan	01/01/2024
Early B-cell development and B-cell maturation are impaired in patients with active hemophagocytic lymphohistiocytosis. Blood	J Shim, S Park, S Venkateswaran, D Kumar, C Prince, V Parihar, L Maples, EK Waller, S Kugathasan, M Briones, M Lee, CJ Henry, S Prahalad, S Chandrakasan	12/07/2023
The role of admixture in the rare variant contribution to inflammatory bowel disease. Genome medicine	C Astore, S Sharma, S Nagpal, DJ Cutler, JD Rioux, JH Cho, DPB McGovern, SR Brant, S Kugathasan, IK Jordan, G Gibson	11/15/2023
Prevalence of tissue transglutaminase antibodies and IgA deficiency are not increased in juvenile idiopathic arthritis: a case-control study. Pediatric rheumatology online journal	AT Kohli, AO Hersh, L Ponder, LHK Chan, KA Rouster-Stevens, AE Tebo, S Kugathasan, SL Guthery, JF Bohnsack, S Prahalad	10/05/2023
Exome Sequencing Implicates DGKZ , ESRRA , and GXYLT1 for Modulating Granuloma Formation in Crohn Disease. Journal of pediatric gastroenterology and nutrition	RA Harris, AH Bush, TN Eagar, J Qian, MP Greenwood, AR Opekun, R Baldassano, SL Guthery, JD Noe, A Otley, JR Rosh, S Kugathasan, R Kellermayer	09/01/2023
Crohn's patients and healthy infants share immunodominant B cell response to commensal flagellin peptide epitopes. bioRxiv : the preprint server for biology	Q Zhao, LW Duck, JT Killian, AF Rosenberg, PJ Mannon, RG King, LA Denson, S Kugathasan, EN Janoff, MC Jenmalm, CO Elson	08/11/2023
Mucosal transcriptomics highlight lncRNAs implicated in ulcerative colitis, Crohn's disease, and celiac disease. JCI insight	T Braun, KE Sosnovski, A Amir, M BenShoshan, KL VanDussen, R Karns, N Levhar, H Abbas-Egbariya, R Hadar, G Efroni, D Castel, C Avivi, MJ Rosen, AM Grifiths, TD Walters, DR Mack, BM Boyle, SA Ali, SR Moore, M Schirmer, RJ Xavier, S Kugathasan, AG Jegga, B Weiss, C Mayer, I Barshack, S Ben-Horin, I Ulitsky, A Beucher, J Ferrer, JS Hyams, LA Denson, Y Haberman	07/24/2023
Comparative Effectiveness of Anti-TNF in Combination With Low-Dose Methotrexate vs Anti-TNF Monotherapy in Pediatric Crohn's Disease: A Pragmatic Randomized Trial. Gastroenterology	MD Kappelman, DA Wohl, HH Herfarth, AM Firestine, J Adler, RF Ammoury, JE Aronow, DM Bass, JA Bass, K Benkov, CB Tobi, ME Boccieri, BM Boyle, WB Brinkman, JM Cabera, K Chun, RB Colletti, CM Dodds, JM Dorsey, DR Ebach, E Entrena, CB Forrest, JA Galanko, JE Grunow, AS Gulati, A Ivanova, TW Jester, JL Kaplan, S Kugathasan, ME Kusek, IH Leibowitz, TM Linville, EA Lipstein, PA Margolis, P Minar, Z Molle-Rios, J Moses, KK Olano, L Osaba, PJ Palomo, H Pappa, KT Park, DS Pashankar, L Pitch, M Robinson, CM Samson, KC Sandberg, JR Schuchard, M Seid, KA Shelly, SJ Steiner, JA Strople, JS Sullivan, J Tung, P Wali, M Zikry, M Weinberger, SA Saeed, A Bousvaros	07/01/2023
GATA6-AS1 Regulates Intestinal Epithelial Mitochondrial Functions, and its Reduced Expression is Linked to Intestinal Inflammation and Less Favourable Disease Course in Ulcerative Colitis. Journal of Crohn's & colitis	KE Sosnovski, T Braun, A Amir, D Moshel, M BenShoshan, KL VanDussen, N Levhar, H Abbas-Egbariya, K Beider, R Ben-Yishay, S Asad Ali, SR Moore, S Kugathasan, I Abramovich, E Glick Saar, B Weiss, I Barshack, E Gottlieb, T Geiger, S Ben-Horin, I Ulitsky, JS Hyams, LA Denson, Y Haberman	06/16/2023
The Use of the Perioperative Nutrition Score in Postoperative Pediatric Inflammatory Bowel Disease Patients. Journal of pediatric surgery	AA Howk, SR Smith, K Polireddy, CG Sauer, S Kugathasan, J Glasson, AA Chahine	06/01/2023
Multicenter Cohort Study of Infliximab Pharmacokinetics and Therapy Response in Pediatric Acute Severe Ulcerative Colitis. Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association	KG Whaley, Y Xiong, R Karns, JS Hyams, S Kugathasan, BM Boyle, TD Walters, J Kelsen, N LeLeiko, J Shapiro, A Waddell, S Fox, R Bezold, S Bruns, R Widing, Y Haberman, MH Collins, T Mizuno, P Minar, GR D'Haens, LA Denson, AA Vinks, MJ Rosen	05/01/2023
Identifying high-impact variants and genes in exomes of Ashkenazi Jewish inflammatory bowel disease patients. Nature communications	Y Wu, K Gettler, ME Kars, M Giri, D Li, CS Bayrak, P Zhang, A Jain, P Maffucci, K Sabic, T Van Vleck, G Nadkarni, LA Denson, H Ostrer, AP Levine, ER Schiff, AW Segal, S Kugathasan, PD Stenson, DN Cooper, L Philip Schumm, S Snapper, MJ Daly, T Haritunians, RH Duerr, MS Silverberg, JD Rioux, SR Brant, DPB McGovern, JH Cho, Y Itan	04/20/2023
Longitudinal DNA methylation profiling of the rectal mucosa identifies cell-specific signatures of disease status, severity and clinical outcomes in ulcerative colitis cell-specific DNA methylation signatures of UC. Clinical epigenetics	S Venkateswaran, HK Somineni, JD Matthews, V Kilaru, JS Hyams, LA Denson, R Kellamayer, G Gibson, DJ Cutler, KN Conneely, AK Smith, S Kugathasan	03/24/2023
Characterization of Intestinal Mesenchymal Stromal Cells From Patients With Inflammatory Bowel Disease for Autologous Cell Therapy. Stem cells translational medicine	M Anbazhagan, D Geem, S Venkateswaran, R Pelia, VL Kolachala, A Dodd, SC Maddipatla, DJ Cutler, JD Matthews, R Chinnadurai, S Kugathasan	03/03/2023
Trans-ancestry, Bayesian meta-analysis discovers 20 novel risk loci for inflammatory bowel disease in an African American, East Asian and European cohort. Human molecular genetics	RY Cordero, JB Cordero, AB Stiemke, LW Datta, S Buyske, S Kugathasan, DPB McGovern, SR Brant, CL Simpson	02/19/2023
Assessing Cellular and Transcriptional Diversity of Ileal Mucosa Among Treatment-Naïve and Treated Crohn's Disease. Inflammatory bowel diseases	SC Maddipatla, VL Kolachala, S Venkateswaran, AF Dodd, RS Pelia, D Geem, H Yin, Y Sun, C Xu, A Mo, A Kosters, J Yang, JD Matthews, E Ghosn, S Kugathasan, P Qiu	02/01/2023
Environmental Interaction of Resolved Human Cytomegalovirus Infection With Crohn's Disease Location. Inflammatory bowel diseases	T Shih, S Yusung, R Gonsky, R Dutra-Clarke, D Ziring, S Rabizadeh, S Kugathasan, LA Denson, D Li, J Braun	02/01/2023
Resistin, Elastase, and Lactoferrin as Potential Plasma Biomarkers of Pediatric Inflammatory Bowel Disease Based on Comprehensive Proteomic Screens. Molecular & cellular proteomics : MCP	ASC Louis Sam Titus, K Vanarsa, S Soomro, A Patel, J Prince, S Kugathasan, C Mohan	02/01/2023
Identifying metabolic shifts in Crohn's disease using' omics-driven contextualized computational metabolic network models. Scientific reports	P Fernandes, Y Sharma, F Zulqarnain, B McGrew, A Shrivastava, L Ehsan, D Payne, L Dillard, D Powers, I Aldridge, J Matthews, S Kugathasan, FM Fernández, D Gaul, JA Papin, S Syed	01/05/2023
Targeted Assessment of Mucosal Immune Gene Expression Predicts Clinical Outcomes in Children with Ulcerative Colitis. Journal of Crohn's & colitis	K Clarkston, R Karns, AG Jegga, M Sharma, S Fox, BA Ojo, P Minar, TD Walters, AM Griffiths, DR Mack, B Boyle, NS LeLeiko, J Markowitz, JR Rosh, AS Patel, S Shah, RN Baldassano, M Pfefferkorn, C Sauer, S Kugathasan, Y Haberman, JS Hyams, LA Denson, MJ Rosen	11/23/2022
Human intestinal myofibroblasts deposited collagen VI enhances adhesiveness for T cells - A novel mechanism for maintenance of intestinal inflammation. Matrix biology : journal of the International Society for Matrix Biology	SN Lin, A Musso, J Wang, PK Mukherjee, GA West, R Mao, R Lyu, J Li, S Zhao, M Elias, Y Haberman, LA Denson, S Kugathasan, MH Chen, D Czarnecki, D Dejanovic, HT Le, J Chandra, J Lipman, SR Steele, QT Nguyen, C Fiocchi, F Rieder	11/01/2022
Large-scale sequencing identifies multiple genes and rare variants associated with Crohn's disease susceptibility. Nature genetics	A Sazonovs, CR Stevens, GR Venkataraman, K Yuan, B Avila, MT Abreu, T Ahmad, M Allez, AN Ananthakrishnan, G Atzmon, A Baras, JC Barrett, N Barzilai, L Beaugerie, A Beecham, CN Bernstein, A Bitton, B Bokemeyer, A Chan, D Chung, I Cleynen, J Cosnes, DJ Cutler, A Daly, OM Damas, LW Datta, N Dawany, M Devoto, S Dodge, E Ellinghaus, L Fachal, M Farkkila, W Faubion, M Ferreira, D Franchimont, SB Gabriel, T Ge, M Georges, K Gettler, M Giri, B Glaser, S Goerg, P Goyette, D Graham, E Hämäläinen, T Haritunians, GA Heap, M Hiltunen, M Hoeppner, JE Horowitz, P Irving, V Iyer, C Jalas, J Kelsen, H Khalili, BS Kirschner, K Kontula, JT Koskela, S Kugathasan, J Kupcinskas, CA Lamb, M Laudes, C Lévesque, AP Levine, JD Lewis, C Liefferinckx, BS Loescher, E Louis, J Mansfield, S May, JL McCauley, E Mengesha, M Mni, P Moayyedi, CJ Moran, RD Newberry, S O'Charoen, DT Okou, B Oldenburg, H Ostrer, A Palotie, J Paquette, J Pekow, I Peter, MJ Pierik, CY Ponsioen, N Pontikos, N Prescott, AE Pulver, S Rahmouni, DL Rice, P Saavalainen, B Sands, RB Sartor, ER Schiff, S Schreiber, LP Schumm, AW Segal, P Seksik, R Shawky, SZ Sheikh, MS Silverberg, A Simmons, J Skeiceviciene, H Sokol, M Solomonson, H Somineni, D Sun, S Targan, D Turner, HH Uhlig, AE van der Meulen, S Vermeire, S Verstockt, MD Voskuil, HS Winter, J Young, RH Duerr, A Franke, SR Brant, J Cho, RK Weersma, M Parkes, RJ Xavier, MA Rivas, JD Rioux, DPB McGovern, H Huang, CA Anderson, MJ Daly	09/01/2022
Eicosatetraynoic Acid and Butyrate Regulate Human Intestinal Organoid Mitochondrial and Extracellular Matrix Pathways Implicated in Crohn's Disease Strictures. Inflammatory bowel diseases	I Jurickova, E Bonkowski, E Angerman, E Novak, A Huron, G Akers, K Iwasawa, T Braun, R Hadar, M Hooker, S Han, DJ Cutler, DT Okou, S Kugathasan, A Jegga, J Wells, T Takebe, KP Mollen, Y Haberman, LA Denson	07/01/2022
Methylation quantitative trait loci are largely consistent across disease states in Crohn's disease. G3 (Bethesda, Md.)	S Venkateswaran, HK Somineni, V Kilaru, S Katrinli, J Prince, DT Okou, JS Hyams, LA Denson, R Kellermayer, G Gibson, DJ Cutler, AK Smith, S Kugathasan, KN Conneely	04/04/2022
Clinical and Host Biological Factors Predict Colectomy Risk in Children Newly Diagnosed With Ulcerative Colitis. Inflammatory bowel diseases	JS Hyams, M Brimacombe, Y Haberman, T Walters, G Gibson, A Mo, D Mack, A Griffiths, B Boyle, N LeLeiko, J Markowitz, J Rosh, A Patel, S Shah, R Baldassano, M Pfefferkorn, C Sauer, J Dailey, S Venkateswaran, S Kugathasan, LA Denson	02/01/2022
Early Change in Fecal Calprotectin Predicts One-Year Outcome in Children Newly Diagnosed With Ulcerative Colitis. Journal of pediatric gastroenterology and nutrition	C Krishnakumar, AN Ananthakrishnan, BM Boyle, AM Griffiths, NS LeLeiko, DR Mack, JF Markowitz, JR Rosh, CG Sauer, TD Walters, E Bonkowski, LA Denson, JS Hyams, S Kugathasan	01/01/2022
Site- and Taxa-Specific Disease-Associated Oral Microbial Structures Distinguish Inflammatory Bowel Diseases. Inflammatory bowel diseases	HK Somineni, JH Weitzner, S Venkateswaran, A Dodd, J Prince, A Karikaran, CG Sauer, S Abramowicz, ME Zwick, DJ Cutler, DT Okou, P Chopra, S Kugathasan	11/15/2021
Association of Baseline Luminal Narrowing With Ileal Microbial Shifts and Gene Expression Programs and Subsequent Transmural Healing in Pediatric Crohn Disease. Inflammatory bowel diseases	AD Ta, NJ Ollberding, R Karns, Y Haberman, AL Alazraki, D Hercules, R Baldassano, J Markowitz, MB Heyman, S Kim, B Kirschner, JM Shapiro, J Noe, M Oliva-Hemker, A Otley, M Pfefferkorn, R Kellermayer, S Snapper, S Rabizadeh, R Xavier, M Dubinsky, J Hyams, S Kugathasan, AG Jegga, JR Dillman, LA Denson	10/20/2021
Stratification of risk of progression to colectomy in ulcerative colitis via measured and predicted gene expression. American journal of human genetics	A Mo, S Nagpal, K Gettler, T Haritunians, M Giri, Y Haberman, R Karns, J Prince, D Arafat, NY Hsu, LS Chuang, C Argmann, A Kasarskis, M Suarez-Farinas, N Gotman, E Mengesha, S Venkateswaran, PA Rufo, SS Baker, CG Sauer, J Markowitz, MD Pfefferkorn, JR Rosh, BM Boyle, DR Mack, RN Baldassano, S Shah, NS LeLeiko, MB Heyman, AM Griffiths, AS Patel, JD Noe, S Davis Thomas, BJ Aronow, TD Walters, DPB McGovern, JS Hyams, S Kugathasan, JH Cho, LA Denson, G Gibson	09/02/2021
Efficacy and safety of adalimumab in paediatric patients with moderate-to-severe ulcerative colitis (ENVISION I): a randomised, controlled, phase 3 study. The lancet. Gastroenterology & hepatology	NM Croft, WA Faubion, S Kugathasan, J Kierkus, FM Ruemmele, T Shimizu, NM Mostafa, M Venetucci, T Finney-Hayward, Y Sanchez Gonzalez, M Bereswill, A Lazar, D Turner	08/01/2021
Profiling non-coding RNA levels with clinical classifiers in pediatric Crohn's disease. BMC medical genomics	R Pelia, S Venkateswaran, JD Matthews, Y Haberman, DJ Cutler, JS Hyams, LA Denson, S Kugathasan	07/29/2021
It Takes Two to Make It Right: Dual Biologic and Small Molecule Therapy for Treatment-Refractory Pediatric Inflammatory Bowel Disease. Inflammatory bowel diseases	D Geem, S Kugathasan	07/27/2021
Altered splicing associated with the pathology of inflammatory bowel disease. Human genomics	K Berger, H Somineni, J Prince, S Kugathasan, G Gibson	07/23/2021
Noninvasive Targeted Crohn Disease Management by Combining Endoscopic Healing Index and Therapeutic Drug Monitoring. Crohn's & colitis 360	A Hemperly, MC Dubinsky, A Yarur, A Afzali, S Hanauer, S Kugathasan, MD Long, S Rabizadeh, R Sockolow, L Okada, A Jain, MT Abreu, N Vande Casteele	07/01/2021
Predicting disease course in ulcerative colitis using stool proteins identified through an aptamer-based screen. Nature communications	S Soomro, S Venkateswaran, K Vanarsa, M Kharboutli, M Nidhi, R Susarla, T Zhang, P Sasidharan, KH Lee, J Rosh, J Markowitz, C Pedroza, LA Denson, J Hyams, S Kugathasan, C Mohan	06/28/2021
Deconvolution of monocyte responses in inflammatory bowel disease reveals an IL-1 cytokine network that regulates IL-23 in genetic and acquired IL-10 resistance. Gut	D Aschenbrenner, M Quaranta, S Banerjee, N Ilott, J Jansen, B Steere, YH Chen, S Ho, K Cox, CV Arancibia-Cárcamo, M Coles, E Gaffney, SP Travis, L Denson, S Kugathasan, J Schmitz, F Powrie, SN Sansom, HH Uhlig	06/01/2021
DUOX2 variants associate with preclinical disturbances in microbiota-immune homeostasis and increased inflammatory bowel disease risk. The Journal of clinical investigation	H Grasberger, AT Magis, E Sheng, MP Conomos, M Zhang, LS Garzotto, G Hou, S Bishu, H Nagao-Kitamoto, M El-Zaatari, S Kitamoto, N Kamada, RW Stidham, Y Akiba, J Kaunitz, Y Haberman, S Kugathasan, LA Denson, GS Omenn, JY Kao	05/03/2021
A myeloid-stromal niche and gp130 rescue in NOD2-driven Crohn's disease. Nature	S Nayar, JK Morrison, M Giri, K Gettler, LS Chuang, LA Walker, HM Ko, E Kenigsberg, S Kugathasan, M Merad, J Chu, JH Cho	05/01/2021
Transethnic analysis of the human leukocyte antigen region for ulcerative colitis reveals not only shared but also ethnicity-specific disease associations. Human molecular genetics	F Degenhardt, G Mayr, M Wendorff, G Boucher, E Ellinghaus, D Ellinghaus, H ElAbd, E Rosati, M Hübenthal, S Juzenas, S Abedian, H Vahedi, BK Thelma, SK Yang, BD Ye, JH Cheon, LW Datta, NE Daryani, P Ellul, M Esaki, Y Fuyuno, DPB McGovern, T Haritunians, M Hong, G Juyal, ES Jung, M Kubo, S Kugathasan, TL Lenz, S Leslie, R Malekzadeh, V Midha, A Motyer, SC Ng, DT Okou, S Raychaudhuri, J Schembri, S Schreiber, K Song, A Sood, A Takahashi, EA Torres, J Umeno, BZ Alizadeh, RK Weersma, SH Wong, K Yamazaki, TH Karlsen, JD Rioux, SR Brant, A Franke	04/27/2021
Common and Rare Variant Prediction and Penetrance of IBD in a Large, Multi-ethnic, Health System-based Biobank Cohort. Gastroenterology	K Gettler, R Levantovsky, A Moscati, M Giri, Y Wu, NY Hsu, LS Chuang, A Sazonovs, S Venkateswaran, U Korie, C Chasteau, RH Duerr, MS Silverberg, SB Snapper, MJ Daly, DP McGovern, SR Brant, JD Rioux, S Kugathasan, CA Anderson, Y Itan, JH Cho	04/01/2021
Whole-genome sequencing of African Americans implicates differential genetic architecture in inflammatory bowel disease. American journal of human genetics	HK Somineni, S Nagpal, S Venkateswaran, DJ Cutler, DT Okou, T Haritunians, CL Simpson, F Begum, LW Datta, AJ Quiros, J Seminerio, E Mengesha, JS Alexander, RN Baldassano, S Dudley-Brown, RK Cross, T Dassopoulos, LA Denson, TA Dhere, H Iskandar, GW Dryden, JK Hou, SZ Hussain, JS Hyams, KL Isaacs, H Kader, MD Kappelman, J Katz, R Kellermayer, JF Kuemmerle, M Lazarev, E Li, P Mannon, DE Moulton, RD Newberry, AS Patel, J Pekow, SA Saeed, JF Valentine, MH Wang, JL McCauley, MT Abreu, T Jester, Z Molle-Rios, S Palle, EJ Scherl, J Kwon, JD Rioux, RH Duerr, MS Silverberg, ME Zwick, C Stevens, MJ Daly, JH Cho, G Gibson, DPB McGovern, SR Brant, S Kugathasan	03/04/2021
Altered Intestinal ACE2 Levels Are Associated With Inflammation, Severe Disease, and Response to Anti-Cytokine Therapy in Inflammatory Bowel Disease. Gastroenterology	AA Potdar, S Dube, T Naito, K Li, G Botwin, T Haritunians, D Li, D Casero, S Yang, J Bilsborough, JG Perrigoue, LA Denson, M Daly, SR Targan, P Fleshner, J Braun, S Kugathasan, TS Stappenbeck, DPB McGovern	02/01/2021
Stressful life events, depression, and the moderating role of psychophysiological reactivity in patients with pediatric inflammatory bowel disease. Journal of psychosomatic research	GK Cushman, S Shih, MG Stolz, RC Hinrichs, T Jovanovic, JL Lee, S Kugathasan, B Reed	02/01/2021
Machine learning identifies novel blood protein predictors of penetrating and stricturing complications in newly diagnosed paediatric Crohn's disease. Alimentary pharmacology & therapeutics	RC Ungaro, L Hu, J Ji, S Nayar, S Kugathasan, LA Denson, J Hyams, MC Dubinsky, BE Sands, JH Cho	01/01/2021
PTSD is associated with increased DNA methylation across regions of HLA-DPB1 and SPATC1L. Brain, behavior, and immunity	S Katrinli, Y Zheng, A Gautam, R Hammamieh, R Yang, S Venkateswaran, V Kilaru, A Lori, R Hinrichs, A Powers, CF Gillespie, AP Wingo, V Michopoulos, T Jovanovic, EJ Wolf, RE McGlinchey, WP Milberg, MW Miller, S Kugathasan, M Jett, MW Logue, KJ Ressler, AK Smith	01/01/2021
Ileal Derived Organoids From Crohn's Disease Patients Show Unique Transcriptomic and Secretomic Signatures. Cellular and molecular gastroenterology and hepatology	BJ Niklinska-Schirtz, S Venkateswaran, M Anbazhagan, VL Kolachala, J Prince, A Dodd, R Chinnadurai, G Gibson, LA Denson, DJ Cutler, AG Jegga, JD Matthews, S Kugathasan	01/01/2021
Analysis of Using the Total White Blood Cell Count to Define Severe New-onset Ulcerative Colitis in Children. Journal of pediatric gastroenterology and nutrition	DR Mack, B Saul, B Boyle, A Griffiths, C Sauer, J Markowitz, N LeLeiko, D Keljo, JR Rosh, SS Baker, S Steiner, MB Heyman, AS Patel, R Baldassano, J Noe, P Rufo, S Kugathasan, T Walters, A Marquis, SM Thomas, L Denson, J Hyams	09/01/2020
Mucosal Inflammatory and Wound Healing Gene Programs Reveal Targets for Stricturing Behavior in Pediatric Crohn's Disease. Journal of Crohn's & colitis	Y Haberman, P Minar, R Karns, PJ Dexheimer, S Ghandikota, S Tegge, D Shapiro, B Shuler, S Venkateswaran, T Braun, A Ta, TD Walters, RN Baldassano, JD Noe, J Rosh, J Markowitz, JL Dotson, DR Mack, R Kellermayer, AM Griffiths, MB Heyman, SS Baker, D Moulton, AS Patel, AS Gulati, SJ Steiner, N LeLeiko, A Otley, M Oliva-Hemker, D Ziring, R Gokhale, S Kim, SL Guthery, SA Cohen, S Snapper, BJ Aronow, M Stephens, G Gibson, JR Dillman, M Dubinsky, JS Hyams, S Kugathasan, AG Jegga, LA Denson	08/08/2020
Similar Long-Term Outcomes in Children Presenting With Abscess vs Phlegmon at Diagnosis of Crohn Disease. Crohn's & colitis 360	AW Fondell, MH Mosha, RM Maltz, BM Boyle, BJ Niklinska-Schirtz, S Kugathasan, ME Gibson, JM Shapiro, SM Rosenheck, AL Langseder, MC Kennedy, JR Rosh, JS Hyams	07/01/2020
Reduced expression of COVID-19 host receptor, ACE2 is associated with small bowel inflammation, more severe disease, and response to anti-TNF therapy in Crohn's disease. medRxiv : the preprint server for health sciences	AA Potdar, S Dube, T Naito, G Botwin, T Haritunians, D Li, S Yang, J Bilsborough, LA Denson, M Daly, SR Targan, P Fleshner, J Braun, S Kugathasan, TS Stappenbeck, DPB McGovern	04/23/2020
Anti-TNF Therapy Is Emerging as the Primary Treatment Modality in Pediatric Inflammatory Bowel Disease. Inflammatory bowel diseases	BJ Niklinska-Schirtz, S Kugathasan	01/01/2020
Performance of Interferon-gamma Release Assays for Tuberculosis Screening in Pediatric Inflammatory Bowel Disease. Journal of pediatric gastroenterology and nutrition	JP Stevens, CR Ballengee, R Chandradevan, AB Thompson, BT Schoen, S Kugathasan, CG Sauer	12/01/2019
Management of Anti-drug Antibodies to Biologic Medications in Children With Inflammatory Bowel Disease. Journal of pediatric gastroenterology and nutrition	RZ Cohen, BT Schoen, S Kugathasan, CG Sauer	11/01/2019
Serologic, but Not Genetic, Markers Are Associated With Impaired Anthropometrics at Diagnosis of Pediatric Crohn's Disease. Journal of pediatric gastroenterology and nutrition	SK Naramore, WE Bennett, G Jiang, S Kugathasan, LA Denson, JS Hyams, SJ Steiner	11/01/2019
Performance of Interferon-Gamma Release Assays for Tuberculosis Screening in Pediatric Inflammatory Bowel Disease. Journal of pediatric gastroenterology and nutrition	JP Stevens, CR Ballengee, R Chandradevan, AB Thompson, BT Schoen, S Kugathasan, CG Sauer	10/01/2019
Characterization of Stool Virome in Children Newly Diagnosed With Moderate to Severe Ulcerative Colitis. Inflammatory bowel diseases	R Tokarz, JS Hyams, DR Mack, B Boyle, AM Griffiths, NS LeLeiko, CG Sauer, S Shah, J Markowitz, SS Baker, J Rosh, RN Baldassano, S Kugathasan, T Walters, T Tagliafierro, S Sameroff, B Lee, X Che, A Oleynik, LA Denson, WI Lipkin	09/18/2019
Single-Cell Analysis of Crohn's Disease Lesions Identifies a Pathogenic Cellular Module Associated with Resistance to Anti-TNF Therapy. Cell	JC Martin, C Chang, G Boschetti, R Ungaro, M Giri, JA Grout, K Gettler, LS Chuang, S Nayar, AJ Greenstein, M Dubinsky, L Walker, A Leader, JS Fine, CE Whitehurst, ML Mbow, S Kugathasan, LA Denson, JS Hyams, JR Friedman, PT Desai, HM Ko, I Laface, G Akturk, EE Schadt, H Salmon, S Gnjatic, AH Rahman, M Merad, JH Cho, E Kenigsberg	09/05/2019
Prioritizing Crohn's disease genes by integrating association signals with gene expression implicates monocyte subsets. Genes and immunity	K Gettler, M Giri, E Kenigsberg, J Martin, LS Chuang, NY Hsu, LA Denson, JS Hyams, A Griffiths, JD Noe, WV Crandall, DR Mack, R Kellermayer, C Abraham, G Hoffman, S Kugathasan, JH Cho	09/01/2019
Association Between Plasma Level of Collagen Type III Alpha 1 Chain and Development of Strictures in Pediatric Patients With Crohn's Disease. Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association	CR Ballengee, RW Stidham, C Liu, MO Kim, J Prince, K Mondal, R Baldassano, M Dubinsky, J Markowitz, N Leleiko, J Hyams, L Denson, S Kugathasan	08/01/2019
Pediatric inflammatory bowel disease: continuous lessons for adult inflammatory bowel disease. Current opinion in gastroenterology	S Ahmed, C Vachaparambil, S Kugathasan	07/01/2019
Early Onset Granulomatous Colitis Associated with a Mutation in NCF4 Resolved with Hematopoietic Stem Cell Transplantation. The Journal of pediatrics	M Wright, S Chandrakasan, DT Okou, H Yin, I Jurickova, LA Denson, S Kugathasan	07/01/2019
Neutrophil GM-CSF signaling in inflammatory bowel disease patients is influenced by non-coding genetic variants. Scientific reports	S Venkateswaran, LA Denson, I Jurickova, A Dodd, ME Zwick, DJ Cutler, S Kugathasan, DT Okou	06/24/2019
Variation in Care in the Management of Children With Crohn's Disease: Data From a Multicenter Inception Cohort Study. Inflammatory bowel diseases	C Krishnakumar, CR Ballengee, C Liu, MO Kim, SS Baker, RN Baldassano, SA Cohen, WV Crandall, LA Denson, MC Dubinsky, J Evans, R Gokhale, A Griffiths, SL Guthery, M Oliva-Hemker, MB Heyman, D Keljo, R Kellermayer, NS Leleiko, DR Mack, JF Markowitz, DE Moulton, JD Noe, AR Otley, AS Patel, M Pfefferkorn, S Rabizadeh, JR Rosh, S Snapper, TD Walters, D Ziring, K Mondal, MD Kappelman, JS Hyams, S Kugathasan	06/18/2019
Blood-Derived DNA Methylation Signatures of Crohn's Disease and Severity of Intestinal Inflammation. Gastroenterology	HK Somineni, S Venkateswaran, V Kilaru, UM Marigorta, A Mo, DT Okou, R Kellermayer, K Mondal, D Cobb, TD Walters, A Griffiths, JD Noe, WV Crandall, JR Rosh, DR Mack, MB Heyman, SS Baker, MC Stephens, RN Baldassano, JF Markowitz, MC Dubinsky, J Cho, JS Hyams, LA Denson, G Gibson, DJ Cutler, KN Conneely, AK Smith, S Kugathasan	06/01/2019
Challenges in IBD Research: Pragmatic Clinical Research. Inflammatory bowel diseases	FI Scott, DT Rubin, S Kugathasan, A Bousvaros, CO Elson, RD Newberry, GY Melmed, J Pekow, JW Fleshman, BM Boyle, U Mahadevan, LM Cannon, MD Long, RK Cross, CY Ha, KL Lasch, AM Robinson, JF Rafferty, JJ Lee, KDC Dahl, A Weaver, N Shtraizent, G Honig, A Hurtado-Lorenzo, CA Heller	05/16/2019
Multi-omics of the gut microbial ecosystem in inflammatory bowel diseases. Nature	J Lloyd-Price, C Arze, AN Ananthakrishnan, M Schirmer, J Avila-Pacheco, TW Poon, E Andrews, NJ Ajami, KS Bonham, CJ Brislawn, D Casero, H Courtney, A Gonzalez, TG Graeber, AB Hall, K Lake, CJ Landers, H Mallick, DR Plichta, M Prasad, G Rahnavard, J Sauk, D Shungin, Y Vázquez-Baeza, RA White, J Braun, LA Denson, JK Jansson, R Knight, S Kugathasan, DPB McGovern, JF Petrosino, TS Stappenbeck, HS Winter, CB Clish, EA Franzosa, H Vlamakis, RJ Xavier, C Huttenhower	05/01/2019
Serum Protein Biomarkers of Fibrosis Aid in Risk Stratification of Future Stricturing Complications in Pediatric Crohn's Disease. The American journal of gastroenterology	J Wu, DM Lubman, S Kugathasan, LA Denson, JS Hyams, MC Dubinsky, AM Griffiths, RN Baldassano, JD Noe, S Rabizadeh, AS Gulati, JR Rosh, WV Crandall, PDR Higgins, RW Stidham	05/01/2019
Clinical and biological predictors of response to standardised paediatric colitis therapy (PROTECT): a multicentre inception cohort study. Lancet (London, England)	JS Hyams, S Davis Thomas, N Gotman, Y Haberman, R Karns, M Schirmer, A Mo, DR Mack, B Boyle, AM Griffiths, NS LeLeiko, CG Sauer, DJ Keljo, J Markowitz, SS Baker, J Rosh, RN Baldassano, A Patel, M Pfefferkorn, A Otley, M Heyman, J Noe, M Oliva-Hemker, PA Rufo, J Strople, D Ziring, SL Guthery, B Sudel, K Benkov, P Wali, D Moulton, J Evans, MD Kappelman, MA Marquis, FA Sylvester, MH Collins, S Venkateswaran, M Dubinsky, V Tangpricha, KL Spada, B Saul, J Wang, J Serrano, K Hommel, UM Marigorta, G Gibson, RJ Xavier, S Kugathasan, T Walters, LA Denson	04/27/2019
Response to the Letter from Drs. Greenstein and Brown. Inflammatory bowel diseases	R Chandradevan, S Kugathasan	04/11/2019
Multilocus Heterotopic Gastric Mucosa of Ileum Masquerading as VEOIBD in a Newborn. Pediatrics	L Lindoso, CR Ballengee, KP Patel, R Romero, S Caltharp, AL Alazraki, S Kugathasan	04/01/2019
Age-of-diagnosis dependent ileal immune intensification and reduced alpha-defensin in older versus younger pediatric Crohn Disease patients despite already established dysbiosis. Mucosal immunology	Y Haberman, M Schirmer, PJ Dexheimer, R Karns, T Braun, MO Kim, TD Walters, RN Baldassano, JD Noe, J Rosh, J Markowitz, WV Crandall, DR Mack, AM Griffiths, MB Heyman, SS Baker, R Kellermayer, D Moulton, AS Patel, AS Gulati, SJ Steiner, N LeLeiko, A Otley, M Oliva-Hemker, D Ziring, BS Kirschner, DJ Keljo, SL Guthery, SA Cohen, S Snapper, J Evans, M Dubinsky, B Aronow, JS Hyams, S Kugathasan, C Huttenhower, RJ Xavier, LA Denson	03/01/2019
Genetic and Transcriptomic Variation Linked to Neutrophil Granulocyte-Macrophage Colony-Stimulating Factor Signaling in Pediatric Crohn's Disease. Inflammatory bowel diseases	LA Denson, I Jurickova, R Karns, KA Shaw, DJ Cutler, D Okou, CA Valencia, A Dodd, K Mondal, BJ Aronow, Y Haberman, A Linn, A Price, R Bezold, K Lake, K Jackson, TD Walters, A Griffiths, RN Baldassano, JD Noe, JS Hyams, WV Crandall, BS Kirschner, MB Heyman, S Snapper, SL Guthery, MC Dubinsky, NS Leleiko, AR Otley, RJ Xavier, C Stevens, MJ Daly, ME Zwick, S Kugathasan	02/21/2019
Genetic variants and pathways implicated in a pediatric inflammatory bowel disease cohort. Genes and immunity	KA Shaw, DJ Cutler, D Okou, A Dodd, BJ Aronow, Y Haberman, C Stevens, TD Walters, A Griffiths, RN Baldassano, JD Noe, JS Hyams, WV Crandall, BS Kirschner, MB Heyman, S Snapper, S Guthery, MC Dubinsky, JM Shapiro, AR Otley, M Daly, LA Denson, S Kugathasan, ME Zwick	02/01/2019
Ulcerative colitis mucosal transcriptomes reveal mitochondriopathy and personalized mechanisms underlying disease severity and treatment response. Nature communications	Y Haberman, R Karns, PJ Dexheimer, M Schirmer, J Somekh, I Jurickova, T Braun, E Novak, L Bauman, MH Collins, A Mo, MJ Rosen, E Bonkowski, N Gotman, A Marquis, M Nistel, PA Rufo, SS Baker, CG Sauer, J Markowitz, MD Pfefferkorn, JR Rosh, BM Boyle, DR Mack, RN Baldassano, S Shah, NS Leleiko, MB Heyman, AM Grifiths, AS Patel, JD Noe, BJ Aronow, S Kugathasan, TD Walters, G Gibson, SD Thomas, K Mollen, S Shen-Orr, C Huttenhower, RJ Xavier, JS Hyams, LA Denson	01/03/2019
Disruption of FOXP3-EZH2 Interaction Represents a Pathobiological Mechanism in Intestinal Inflammation. Cellular and molecular gastroenterology and hepatology	AO Bamidele, PA Svingen, MR Sagstetter, OF Sarmento, M Gonzalez, MB Braga Neto, S Kugathasan, G Lomberk, RA Urrutia, WA Faubion	01/01/2019
The Microbiome in Patients With Inflammatory Diseases. Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association	HK Somineni, S Kugathasan	01/01/2019
Pediatric Inflammatory Bowel Disease Clinical Innovations Meeting of the Crohn's & Colitis Foundation: Charting the Future of Pediatric IBD. Inflammatory bowel diseases	JA Picoraro, D Lee, CA Heller, A Weaver, JS Hyams, LS Conklin, A Otley, D Ziring, S Kugathasan, JR Rosh, A Mulberg, LA Denson, MD Kappelman, AB Grossman, A Bousvaros, KT Park	01/01/2019
Compositional and Temporal Changes in the Gut Microbiome of Pediatric Ulcerative Colitis Patients Are Linked to Disease Course. Cell host & microbe	M Schirmer, L Denson, H Vlamakis, EA Franzosa, S Thomas, NM Gotman, P Rufo, SS Baker, C Sauer, J Markowitz, M Pfefferkorn, M Oliva-Hemker, J Rosh, A Otley, B Boyle, D Mack, R Baldassano, D Keljo, N LeLeiko, M Heyman, A Griffiths, AS Patel, J Noe, S Kugathasan, T Walters, C Huttenhower, J Hyams, RJ Xavier	10/10/2018
The Effect of Early-Life Environmental Exposures on Disease Phenotype and Clinical Course of Crohn's Disease in Children. The American journal of gastroenterology	L Lindoso, K Mondal, S Venkateswaran, HK Somineni, C Ballengee, TD Walters, A Griffiths, JD Noe, W Crandall, S Snapper, S Rabizadeh, JR Rosh, N LeLeiko, S Guthery, D Mack, R Kellermayer, AS Gulati, MD Pfefferkorn, DE Moulton, D Keljo, S Cohen, M Oliva-Hemker, MB Heyman, A Otley, SS Baker, JS Evans, BS Kirschner, AS Patel, D Ziring, MC Stephens, R Baldassano, MC Dubinsky, J Markowitz, LA Denson, J Hyams, S Kugathasan, AN Ananthakrishnan	10/01/2018
Microbiota-sensitive epigenetic signature predicts inflammation in Crohn's disease. JCI insight	D Kelly, M Kotliar, V Woo, S Jagannathan, J Whitt, J Moncivaiz, BJ Aronow, MC Dubinsky, JS Hyams, JF Markowitz, RN Baldassano, MC Stephens, TD Walters, S Kugathasan, Y Haberman, N Sundaram, MJ Rosen, M Helmrath, R Karns, A Barski, LA Denson, T Alenghat	09/20/2018
Evolution of Pediatric Inflammatory Bowel Disease Unclassified (IBD-U): Incorporated With Serological and Gene Expression Profiles. Inflammatory bowel diseases	R Chandradevan, T Hofmekler, K Mondal, N Harun, S Venkateswaran, HK Somineni, CR Ballengee, MO Kim, A Griffiths, JD Noe, WV Crandall, S Snapper, S Rabizadeh, JR Rosh, TD Walters, M Bertha, MC Dubinsky, LA Denson, CG Sauer, JF Markowitz, NS LeLeiko, JS Hyams, S Kugathasan	09/15/2018
Response to Biologics Delay Progression of Crohn's Disease in Children but Not Early Surgery. Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association	CR Ballengee, S Kugathasan	09/01/2018
Targeted Gene Sequencing in Children with Crohn's Disease and Their Parents: Implications for Missing Heritability. G3 (Bethesda, Md.)	JS Chen, F Hu, S Kugathasan, LB Jorde, D Nix, A Rutherford, L Denson, WS Watkins, S Prahalad, C Huff, SL Guthery	08/30/2018
PFOA and ulcerative colitis. Environmental research	K Steenland, S Kugathasan, DB Barr	08/01/2018
Two-Year-Old With a Limp and Suspected Nonaccidental Injury. Journal of pediatric gastroenterology and nutrition	M Manyapu, GJ Warraich, S Kugathasan, S Syed	07/01/2018
Disease-specific regulation of gene expression in a comparative analysis of juvenile idiopathic arthritis and inflammatory bowel disease. Genome medicine	A Mo, UM Marigorta, D Arafat, LHK Chan, L Ponder, SR Jang, J Prince, S Kugathasan, S Prahalad, G Gibson	06/27/2018
Clinical and Genomic Correlates of Neutrophil Reactive Oxygen Species Production in Pediatric Patients With Crohn's Disease. Gastroenterology	LA Denson, I Jurickova, R Karns, KA Shaw, DJ Cutler, DT Okou, A Dodd, K Quinn, K Mondal, BJ Aronow, Y Haberman, A Linn, A Price, R Bezold, K Lake, K Jackson, TD Walters, A Griffiths, RN Baldassano, JD Noe, JS Hyams, WV Crandall, BS Kirschner, MB Heyman, S Snapper, SL Guthery, MC Dubinsky, NS Leleiko, AR Otley, RJ Xavier, C Stevens, MJ Daly, ME Zwick, S Kugathasan	06/01/2018
Serologic Reactivity Reflects Clinical Expression of Ulcerative Colitis in Children. Inflammatory bowel diseases	EA Spencer, SM Davis, DR Mack, BM Boyle, AM Griffiths, NS LeLeiko, CG Sauer, DJ Keljo, JF Markowitz, SS Baker, JR Rosh, RN Baldassano, M Oliva-Hemker, MD Pfefferkorn, AR Otley, MB Heyman, JD Noe, AS Patel, PA Rufo, M Alison Marquis, TD Walters, MH Collins, S Kugathasan, LA Denson, JS Hyams, MC Dubinsky	05/18/2018
Familial Association of Granulocyte-Macrophage Colony-Stimulating Factor Autoantibodies in Inflammatory Bowel Disease. Journal of pediatric gastroenterology and nutrition	SS Wright, A Trauernicht, E Bonkowski, CA McCall, EA Maier, R Bezold, K Lake, C Chalk, BC Trapnell, MO Kim, S Kugathasan, LA Denson	05/01/2018
Enhanced Contribution of HLA in Pediatric Onset Ulcerative Colitis. Inflammatory bowel diseases	S Venkateswaran, J Prince, DJ Cutler, UM Marigorta, DT Okou, S Prahalad, D Mack, B Boyle, T Walters, A Griffiths, CG Sauer, N LeLeiko, D Keljo, J Markowitz, SS Baker, J Rosh, M Pfefferkorn, MB Heyman, A Patel, A Otley, R Baldassano, J Noe, P Rufo, M Oliva-Hemker, S Davis, ME Zwick, G Gibson, LA Denson, J Hyams, S Kugathasan	03/19/2018
Dynamics of metatranscription in the inflammatory bowel disease gut microbiome. Nature microbiology	M Schirmer, EA Franzosa, J Lloyd-Price, LJ McIver, R Schwager, TW Poon, AN Ananthakrishnan, E Andrews, G Barron, K Lake, M Prasad, J Sauk, B Stevens, RG Wilson, J Braun, LA Denson, S Kugathasan, DPB McGovern, H Vlamakis, RJ Xavier, C Huttenhower	03/01/2018
Potency Analysis of Mesenchymal Stromal Cells Using a Combinatorial Assay Matrix Approach. Cell reports	R Chinnadurai, D Rajan, M Qayed, D Arafat, M Garcia, Y Liu, S Kugathasan, LJ Anderson, G Gibson, J Galipeau	02/27/2018
Free and Bioavailable 25-Hydroxyvitamin D Concentrations are Associated With Disease Activity in Pediatric Patients With Newly Diagnosed Treatment Naïve Ulcerative Colitis. Inflammatory bowel diseases	CG Sauer, MS Loop, S Venkateswaran, V Tangpricha, TR Ziegler, A Dhawan, C McCall, E Bonkowski, DR Mack, B Boyle, AM Griffiths, NS Leleiko, DJ Keljo, J Markowitz, SS Baker, J Rosh, RN Baldassano, S Davis, S Patel, J Wang, A Marquis, KL Spada, S Kugathasan, T Walters, JS Hyams, LA Denson	02/15/2018
Long ncRNA Landscape in the Ileum of Treatment-Naive Early-Onset Crohn Disease. Inflammatory bowel diseases	Y Haberman, M BenShoshan, A Di Segni, PJ Dexheimer, T Braun, B Weiss, TD Walters, RN Baldassano, JD Noe, J Markowitz, J Rosh, MB Heyman, AM Griffiths, WV Crandall, DR Mack, SS Baker, R Kellermayer, A Patel, A Otley, SJ Steiner, AS Gulati, SL Guthery, N LeLeiko, D Moulton, BS Kirschner, S Snapper, C Avivi, I Barshack, M Oliva-Hemker, SA Cohen, DJ Keljo, D Ziring, Y Anikster, B Aronow, JS Hyams, S Kugathasan, LA Denson	01/18/2018
Bowel Location Rather Than Disease Subtype Dominates Transcriptomic Heterogeneity in Pediatric IBD. Cellular and molecular gastroenterology and hepatology	S Venkateswaran, UM Marigorta, LA Denson, JS Hyams, G Gibson, S Kugathasan	01/01/2018
Multi-Site Comparison of Patient, Parent, and Pediatric Provider Perspectives on Transition to Adult Care in IBD. Journal of pediatric nursing	WN Gray, B Reed-Knight, PJ Morgan, E Holbrook, S Kugathasan, SA Saeed, LA Denson, KA Hommel	01/01/2018
IBD Serology and Disease Outcomes in African Americans With Crohn's Disease. Inflammatory bowel diseases	M Bertha, A Vasantharoopan, A Kumar, BB Bruce, J Prince, T Hofmekler, D Okou, P Chopra, G Wang, C Sauer, CJ Landers, SZ Hussain, RK Cross, RN Baldassano, MD Kappelman, J Katz, JS Alexander, BS Kirschner, DE Moulton, BO Osuntokun, A Patel, S Saeed, JA Klapproth, TA Dhere, MC Dubinsky, D McGovern, S Kugathasan	12/19/2017
Factors associated with early outcomes following standardised therapy in children with ulcerative colitis (PROTECT): a multicentre inception cohort study. The lancet. Gastroenterology & hepatology	JS Hyams, S Davis, DR Mack, B Boyle, AM Griffiths, NS LeLeiko, CG Sauer, DJ Keljo, J Markowitz, SS Baker, J Rosh, RN Baldassano, A Patel, M Pfefferkorn, A Otley, M Heyman, J Noe, M Oliva-Hemker, P Rufo, J Strople, D Ziring, SL Guthery, B Sudel, K Benkov, P Wali, D Moulton, J Evans, MD Kappelman, A Marquis, FA Sylvester, MH Collins, S Venkateswaran, M Dubinsky, V Tangpricha, KL Spada, A Britt, B Saul, N Gotman, J Wang, J Serrano, S Kugathasan, T Walters, LA Denson	12/01/2017
A novel Ruminococcus gnavus clade enriched in inflammatory bowel disease patients. Genome medicine	AB Hall, M Yassour, J Sauk, A Garner, X Jiang, T Arthur, GK Lagoudas, T Vatanen, N Fornelos, R Wilson, M Bertha, M Cohen, J Garber, H Khalili, D Gevers, AN Ananthakrishnan, S Kugathasan, ES Lander, P Blainey, H Vlamakis, RJ Xavier, C Huttenhower	11/28/2017
PUFAs and IBD: Is There a Relationship? Inflammatory bowel diseases	L Lindoso, S Venkateswaran, S Kugathasan	11/01/2017
Histologic Correlates of Clinical and Endoscopic Severity in Children Newly Diagnosed With Ulcerative Colitis. The American journal of surgical pathology	B Boyle, MH Collins, Z Wang, D Mack, A Griffiths, C Sauer, J Markowitz, N LeLeiko, D Keljo, J Rosh, SS Baker, M Pfefferkorn, M Heyman, A Patel, R Baldassano, J Noe, P Rufo, S Kugathasan, T Walters, L Denson, J Hyams	11/01/2017
Combination Therapy in Pediatric Inflammatory Bowel Disease: Yes, No, Maybe. Inflammatory bowel diseases	JS Hyams, S Kugathasan, MC Dubinsky	10/01/2017
Transcriptional risk scores link GWAS to eQTLs and predict complications in Crohn's disease. Nature genetics	UM Marigorta, LA Denson, JS Hyams, K Mondal, J Prince, TD Walters, A Griffiths, JD Noe, WV Crandall, JR Rosh, DR Mack, R Kellermayer, MB Heyman, SS Baker, MC Stephens, RN Baldassano, JF Markowitz, MO Kim, MC Dubinsky, J Cho, BJ Aronow, S Kugathasan, G Gibson	10/01/2017
Exclusive and partial enteral nutrition for Crohn's disease - Authors' reply. Lancet (London, England)	S Kugathasan, LA Denson, JS Hyams	09/23/2017
Vitamin D Status Is Associated with Hepcidin and Hemoglobin Concentrations in Children with Inflammatory Bowel Disease. Inflammatory bowel diseases	S Syed, ES Michalski, V Tangpricha, S Chesdachai, A Kumar, J Prince, TR Ziegler, PS Suchdev, S Kugathasan	09/01/2017
Mucosal Healing in Clinical Practice: A Single-Center Pediatric IBD Experience. Inflammatory bowel diseases	SL Santha, PR Shankar, A Pan, B Schoen, S Kugathasan, CG Sauer	08/01/2017
Infliximab Is Not Associated With Increased Risk of Malignancy or Hemophagocytic Lymphohistiocytosis in Pediatric Patients With Inflammatory Bowel Disease. Gastroenterology	JS Hyams, MC Dubinsky, RN Baldassano, RB Colletti, S Cucchiara, J Escher, W Faubion, J Fell, BD Gold, A Griffiths, S Koletzko, S Kugathasan, J Markowitz, FM Ruemmele, G Veereman, H Winter, N Masel, CR Shin, KL Tang, M Thayu	06/01/2017
Reply. Gastroenterology	DT Okou, SR Brant, CL Simpson, T Haritunians, C Huang, DPB McGovern, S Kugathasan	06/01/2017
Impaired antibacterial autophagy links granulomatous intestinal inflammation in Niemann-Pick disease type C1 and XIAP deficiency with NOD2 variants in Crohn's disease. Gut	T Schwerd, S Pandey, HT Yang, K Bagola, E Jameson, J Jung, RH Lachmann, N Shah, SY Patel, C Booth, H Runz, G Düker, R Bettels, M Rohrbach, S Kugathasan, H Chapel, S Keshav, A Elkadri, N Platt, AM Muise, S Koletzko, RJ Xavier, T Marquardt, F Powrie, JE Wraith, M Gyrd-Hansen, FM Platt, HH Uhlig	06/01/2017
Mucosal Expression of Type 2 and Type 17 Immune Response Genes Distinguishes Ulcerative Colitis From Colon-Only Crohn's Disease in Treatment-Naive Pediatric Patients. Gastroenterology	MJ Rosen, R Karns, JE Vallance, R Bezold, A Waddell, MH Collins, Y Haberman, P Minar, RN Baldassano, JS Hyams, SS Baker, R Kellermayer, JD Noe, AM Griffiths, JR Rosh, WV Crandall, MB Heyman, DR Mack, MD Kappelman, J Markowitz, DE Moulton, NS Leleiko, TD Walters, S Kugathasan, KT Wilson, SP Hogan, LA Denson	05/01/2017
Use of Reticulocyte Hemoglobin Content in the Assessment of Iron Deficiency in Children With Inflammatory Bowel Disease. Journal of pediatric gastroenterology and nutrition	S Syed, S Kugathasan, A Kumar, J Prince, BT Schoen, C McCracken, TR Ziegler, PS Suchdev	05/01/2017
IBD: Genetic differences in Crohn's disease susceptibility and outcome. Nature reviews. Gastroenterology & hepatology	K Mondal, S Kugathasan	05/01/2017
Prediction of complicated disease course for children newly diagnosed with Crohn's disease: a multicentre inception cohort study. Lancet (London, England)	S Kugathasan, LA Denson, TD Walters, MO Kim, UM Marigorta, M Schirmer, K Mondal, C Liu, A Griffiths, JD Noe, WV Crandall, S Snapper, S Rabizadeh, JR Rosh, JM Shapiro, S Guthery, DR Mack, R Kellermayer, MD Kappelman, S Steiner, DE Moulton, D Keljo, S Cohen, M Oliva-Hemker, MB Heyman, AR Otley, SS Baker, JS Evans, BS Kirschner, AS Patel, D Ziring, BC Trapnell, FA Sylvester, MC Stephens, RN Baldassano, JF Markowitz, J Cho, RJ Xavier, C Huttenhower, BJ Aronow, G Gibson, JS Hyams, MC Dubinsky	04/29/2017
Infliximab Optimization Based on Therapeutic Drug Monitoring in Pediatric Inflammatory Bowel Disease. Journal of pediatric gastroenterology and nutrition	T Hofmekler, M Bertha, C McCracken, B Martineau, E McKinnon, BT Schoen, BO McElhanon, G Tenjarla, S Kugathasan, CG Sauer	04/01/2017
A Microbiome Foundation for the Study of Crohn's Disease. Cell host & microbe	D Gevers, S Kugathasan, D Knights, AD Kostic, R Knight, RJ Xavier	03/08/2017
Nonclassic Inflammatory Bowel Disease in Young Infants: Immune Dysregulation, Polyendocrinopathy, Enteropathy, X-Linked Syndrome, and Other Disorders. Pediatric clinics of North America	S Chandrakasan, S Venkateswaran, S Kugathasan	02/01/2017
Genome-Wide Association Study Identifies African-Specific Susceptibility Loci in African Americans With Inflammatory Bowel Disease. Gastroenterology	SR Brant, DT Okou, CL Simpson, DJ Cutler, T Haritunians, JP Bradfield, P Chopra, J Prince, F Begum, A Kumar, C Huang, S Venkateswaran, LW Datta, Z Wei, K Thomas, LJ Herrinton, JA Klapproth, AJ Quiros, J Seminerio, Z Liu, JS Alexander, RN Baldassano, S Dudley-Brown, RK Cross, T Dassopoulos, LA Denson, TA Dhere, GW Dryden, JS Hanson, JK Hou, SZ Hussain, JS Hyams, KL Isaacs, H Kader, MD Kappelman, J Katz, R Kellermayer, BS Kirschner, JF Kuemmerle, JH Kwon, M Lazarev, E Li, D Mack, P Mannon, DE Moulton, RD Newberry, BO Osuntokun, AS Patel, SA Saeed, SR Targan, JF Valentine, MH Wang, M Zonca, JD Rioux, RH Duerr, MS Silverberg, JH Cho, H Hakonarson, ME Zwick, DP McGovern, S Kugathasan	01/01/2017
Approach to a Child with Colitis. Indian journal of pediatrics	SK Palle, M Prasad, S Kugathasan	11/01/2016
A Frameshift in CSF2RB Predominant Among Ashkenazi Jews Increases Risk for Crohn's Disease and Reduces Monocyte Signaling via GM-CSF. Gastroenterology	LS Chuang, N Villaverde, KY Hui, A Mortha, A Rahman, AP Levine, T Haritunians, SM Evelyn Ng, W Zhang, NY Hsu, JA Facey, T Luong, H Fernandez-Hernandez, D Li, M Rivas, ER Schiff, A Gusev, LP Schumm, BM Bowen, Y Sharma, K Ning, R Remark, S Gnjatic, P Legnani, J George, BE Sands, JM Stempak, LW Datta, S Lipka, S Katz, AS Cheifetz, N Barzilai, N Pontikos, C Abraham, MJ Dubinsky, S Targan, K Taylor, JI Rotter, EJ Scherl, RJ Desnick, MT Abreu, H Zhao, G Atzmon, I Pe'er, S Kugathasan, H Hakonarson, JL McCauley, T Lencz, A Darvasi, V Plagnol, MS Silverberg, AM Muise, SR Brant, MJ Daly, AW Segal, RH Duerr, M Merad, DP McGovern, I Peter, JH Cho	10/01/2016
A Pleiotropic Missense Variant in SLC39A8 Is Associated With Crohn's Disease and Human Gut Microbiome Composition. Gastroenterology	D Li, JP Achkar, T Haritunians, JP Jacobs, KY Hui, M D'Amato, S Brand, G Radford-Smith, J Halfvarson, JH Niess, S Kugathasan, C Büning, LP Schumm, L Klei, A Ananthakrishnan, G Aumais, L Baidoo, M Dubinsky, C Fiocchi, J Glas, R Milgrom, DD Proctor, M Regueiro, LA Simms, JM Stempak, SR Targan, L Törkvist, Y Sharma, B Devlin, J Borneman, H Hakonarson, RJ Xavier, M Daly, SR Brant, JD Rioux, MS Silverberg, JH Cho, J Braun, DP McGovern, RH Duerr	10/01/2016
Dysbiosis, inflammation, and response to treatment: a longitudinal study of pediatric subjects with newly diagnosed inflammatory bowel disease. Genome medicine	KA Shaw, M Bertha, T Hofmekler, P Chopra, T Vatanen, A Srivatsa, J Prince, A Kumar, C Sauer, ME Zwick, GA Satten, AD Kostic, JG Mulle, RJ Xavier, S Kugathasan	07/13/2016
Management of Acute Severe Colitis in Children With Ulcerative Colitis in the Biologics Era. Pediatrics	C Romano, S Syed, S Valenti, S Kugathasan	05/01/2016
Magnetic Resonance Enterography Healing and Magnetic Resonance Enterography Remission Predicts Improved Outcome in Pediatric Crohn Disease. Journal of pediatric gastroenterology and nutrition	CG Sauer, JP Middleton, C McCracken, J Loewen, K Braithwaite, A Alazraki, DR Martin, S Kugathasan	03/01/2016
Pilot Study Evaluating Efficacy of 2 Regimens for Hypovitaminosis D Repletion in Pediatric Inflammatory Bowel Disease. Journal of pediatric gastroenterology and nutrition	RZ Simek, J Prince, S Syed, CG Sauer, B Martineau, T Hofmekler, AJ Freeman, A Kumar, BO McElhanon, BT Schoen, G Tenjarla, C McCracken, TR Ziegler, V Tangpricha, S Kugathasan	02/01/2016
IBD LIVE Case Series--Case 3: Very Early-Onset Inflammatory Bowel Disease: When Genetic Testing Proves Beneficial. Inflammatory bowel diseases	WM Sunseri, S Kugathasan, DJ Keljo, JB Greer, S Ranganathan, RK Cross, CA Siegel, MD Regueiro	12/01/2015
Characterization of genetic loci that affect susceptibility to inflammatory bowel diseases in African Americans. Gastroenterology	C Huang, T Haritunians, DT Okou, DJ Cutler, ME Zwick, KD Taylor, LW Datta, JC Maranville, Z Liu, S Ellis, P Chopra, JS Alexander, RN Baldassano, RK Cross, T Dassopoulos, TA Dhere, RH Duerr, JS Hanson, JK Hou, SZ Hussain, KL Isaacs, KE Kachelries, H Kader, MD Kappelman, J Katz, R Kellermayer, BS Kirschner, JF Kuemmerle, A Kumar, JH Kwon, M Lazarev, P Mannon, DE Moulton, BO Osuntokun, A Patel, JD Rioux, JI Rotter, S Saeed, EJ Scherl, MS Silverberg, A Silverman, SR Targan, JF Valentine, MH Wang, CL Simpson, SL Bridges, RP Kimberly, SS Rich, JH Cho, AD Rienzo, LWH Kao, DPB McGovern, SR Brant, S Kugathasan	11/01/2015
Genetic sharing and heritability of paediatric age of onset autoimmune diseases. Nature communications	YR Li, SD Zhao, J Li, JP Bradfield, M Mohebnasab, L Steel, J Kobie, DJ Abrams, FD Mentch, JT Glessner, Y Guo, Z Wei, JJ Connolly, CJ Cardinale, M Bakay, D Li, SM Maggadottir, KA Thomas, H Qui, RM Chiavacci, CE Kim, F Wang, J Snyder, B Flatø, Ø Førre, LA Denson, SD Thompson, ML Becker, SL Guthery, A Latiano, E Perez, E Resnick, C Strisciuglio, A Staiano, E Miele, MS Silverberg, BA Lie, M Punaro, RK Russell, DC Wilson, MC Dubinsky, DS Monos, V Annese, JE Munro, C Wise, H Chapel, C Cunningham-Rundles, JS Orange, EM Behrens, KE Sullivan, S Kugathasan, AM Griffiths, J Satsangi, SFA Grant, PMA Sleiman, TH Finkel, C Polychronakos, RN Baldassano, ET Luning Prak, JA Ellis, H Li, BJ Keating, H Hakonarson	10/09/2015
Genetics of Inflammatory Bowel Diseases. Gastroenterology	DP McGovern, S Kugathasan, JH Cho	10/01/2015
Meta-analysis of shared genetic architecture across ten pediatric autoimmune diseases. Nature medicine	YR Li, J Li, SD Zhao, JP Bradfield, FD Mentch, SM Maggadottir, C Hou, DJ Abrams, D Chang, F Gao, Y Guo, Z Wei, JJ Connolly, CJ Cardinale, M Bakay, JT Glessner, D Li, C Kao, KA Thomas, H Qiu, RM Chiavacci, CE Kim, F Wang, J Snyder, MD Richie, B Flatø, Ø Førre, LA Denson, SD Thompson, ML Becker, SL Guthery, A Latiano, E Perez, E Resnick, RK Russell, DC Wilson, MS Silverberg, V Annese, BA Lie, M Punaro, MC Dubinsky, DS Monos, C Strisciuglio, A Staiano, E Miele, S Kugathasan, JA Ellis, JE Munro, KE Sullivan, CA Wise, H Chapel, C Cunningham-Rundles, SF Grant, JS Orange, PM Sleiman, EM Behrens, AM Griffiths, J Satsangi, TH Finkel, A Keinan, ET Prak, C Polychronakos, RN Baldassano, H Li, BJ Keating, H Hakonarson	09/01/2015
Improved integrative framework combining association data with gene expression features to prioritize Crohn's disease genes. Human molecular genetics	K Ning, K Gettler, W Zhang, SM Ng, BM Bowen, J Hyams, MC Stephens, S Kugathasan, LA Denson, EE Schadt, GE Hoffman, JH Cho	07/15/2015
Mesenchymal Stromal Cells Derived From Crohn's Patients Deploy Indoleamine 2,3-dioxygenase-mediated Immune Suppression, Independent of Autophagy. Molecular therapy : the journal of the American Society of Gene Therapy	R Chinnadurai, IB Copland, S Ng, M Garcia, M Prasad, D Arafat, G Gibson, S Kugathasan, J Galipeau	07/01/2015
Hidradenitis suppurativa and pediatric Crohn disease. Journal of pediatric gastroenterology and nutrition	B Natarajan, C Sauer, B Shehata, S Kugathasan	04/01/2015
Dissecting Allele Architecture of Early Onset IBD Using High-Density Genotyping. PloS one	DJ Cutler, ME Zwick, DT Okou, S Prahalad, T Walters, SL Guthery, M Dubinsky, R Baldassano, WV Crandall, J Rosh, J Markowitz, M Stephens, R Kellermayer, M Pfefferkorn, MB Heyman, N LeLeiko, D Mack, D Moulton, MD Kappelman, A Kumar, J Prince, P Bose, K Mondal, D Ramachandran, JF Bohnsack, AM Griffiths, Y Haberman, J Essers, SD Thompson, B Aronow, DJ Keljo, JS Hyams, LA Denson, S Kugathasan	01/01/2015
Role of genetics in pediatric inflammatory bowel disease. Inflammatory bowel diseases	DT Okou, S Kugathasan	10/01/2014
A 14-year-old girl with recurrent vulvar abscess. Journal of pediatric and adolescent gynecology	R Bicette, G Tenjarla, S Kugathasan, A Alazraki, L Haddad	08/01/2014
Utility of neutrophil Fcγ receptor I (CD64) index as a biomarker for mucosal inflammation in pediatric Crohn's disease. Inflammatory bowel diseases	P Minar, Y Haberman, I Jurickova, T Wen, ME Rothenberg, MO Kim, SA Saeed, RN Baldassano, M Stephens, J Markowitz, J Rosh, WV Crandall, MB Heyman, DR Mack, AM Griffiths, SS Baker, JS Hyams, S Kugathasan, LA Denson	06/01/2014
Exome sequencing identifies a novel FOXP3 mutation in a 2-generation family with inflammatory bowel disease. Journal of pediatric gastroenterology and nutrition	DT Okou, K Mondal, WA Faubion, LJ Kobrynski, LA Denson, JG Mulle, D Ramachandran, Y Xiong, P Svingen, V Patel, P Bose, JP Waters, S Prahalad, DJ Cutler, ME Zwick, S Kugathasan	05/01/2014
The treatment-naive microbiome in new-onset Crohn's disease. Cell host & microbe	D Gevers, S Kugathasan, LA Denson, Y Vázquez-Baeza, W Van Treuren, B Ren, E Schwager, D Knights, SJ Song, M Yassour, XC Morgan, AD Kostic, C Luo, A González, D McDonald, Y Haberman, T Walters, S Baker, J Rosh, M Stephens, M Heyman, J Markowitz, R Baldassano, A Griffiths, F Sylvester, D Mack, S Kim, W Crandall, J Hyams, C Huttenhower, R Knight, RJ Xavier	03/12/2014
Increased effectiveness of early therapy with anti-tumor necrosis factor-α vs an immunomodulator in children with Crohn's disease. Gastroenterology	TD Walters, MO Kim, LA Denson, AM Griffiths, M Dubinsky, J Markowitz, R Baldassano, W Crandall, J Rosh, M Pfefferkorn, A Otley, MB Heyman, N LeLeiko, S Baker, SL Guthery, J Evans, D Ziring, R Kellermayer, M Stephens, D Mack, M Oliva-Hemker, AS Patel, B Kirschner, D Moulton, S Cohen, S Kim, C Liu, J Essers, S Kugathasan, JS Hyams	02/01/2014
Vitamin D status and bone mineral density in African American children with Crohn disease. Journal of pediatric gastroenterology and nutrition	JP Middleton, AP Bhagavathula, B Gaye, JA Alvarez, CS Huang, CG Sauer, G Tenjarla, BT Schoen, A Kumar, M Prasad, DT Okou, WC Ifeadike, TA Dhere, KN Conneely, TR Ziegler, V Tangpricha, S Kugathasan	11/01/2013
A practical and novel method to extract genomic DNA from blood collection kits for plasma protein preservation. Journal of visualized experiments : JoVE	J Waters, V Dhere, A Benjamin, A Sekar, A Kumar, S Prahalad, DT Okou, S Kugathasan	05/18/2013
Vertebral osteomyelitis due to Candida parapsilosis in a child with Crohn disease while receiving anti-TNF therapy. Journal of pediatric gastroenterology and nutrition	A Huang, C Huang, S Kugathasan	04/01/2013
Challenges in IBD research: update on progress and prioritization of the CCFA's research agenda. Inflammatory bowel diseases	LA Denson, MD Long, DP McGovern, S Kugathasan, GD Wu, VB Young, TT Pizarro, EF de Zoeten, TS Stappenbeck, SE Plevy, C Abraham, A Nusrat, C Jobin, DF McCole, CA Siegel, PD Higgins, HH Herfarth, J Hyams, WJ Sandborn, EV Loftus, MD Kappelman, JD Lewis, CA Parkos, RB Sartor	01/01/2013
Common NOD2 risk variants in African Americans with Crohn's disease are due exclusively to recent Caucasian admixture. Inflammatory bowel diseases	O Adeyanju, DT Okou, C Huang, A Kumar, C Sauer, C Galloway, M Prasad, J Waters, DJ Cutler, ME Zwick, T Dhere, S Kugathasan	12/01/2012
Comparison of magnetic resonance enterography with endoscopy, histopathology, and laboratory evaluation in pediatric Crohn disease. Journal of pediatric gastroenterology and nutrition	CG Sauer, JP Middleton, A Alazraki, UK Udayasankar, B Kalb, KE Applegate, DR Martin, S Kugathasan	08/01/2012
Markers that differentiate early from late IBD. Digestive diseases (Basel, Switzerland)	C Huang, S Kugathasan	01/01/2012
Medical radiation exposure in children with inflammatory bowel disease estimates high cumulative doses. Inflammatory bowel diseases	CG Sauer, S Kugathasan, DR Martin, KE Applegate	11/01/2011
Rising incidence of inflammatory bowel disease in young children: What does the future hold? Journal of pediatric gastroenterology and nutrition	S Kunde, M Prasad, S Kugathasan	08/01/2011
Inflammatory bowel disease in children: current trends. Journal of gastroenterology	G Shikhare, S Kugathasan	07/01/2010
Pediatric inflammatory bowel disease: highlighting pediatric differences in IBD. The Medical clinics of North America	CG Sauer, S Kugathasan	01/01/2010
Pediatric inflammatory bowel disease: highlighting pediatric differences in IBD. Gastroenterology clinics of North America	CG Sauer, S Kugathasan	12/01/2009
Genetic determinants of pediatric inflammatory bowel disease: is age of onset genetically determined? Digestive diseases (Basel, Switzerland)	R Scherr, J Essers, H Hakonarson, S Kugathasan	01/01/2009

Awards

Dr. Kugathasan's various awards and honors include the following:

MilliPub Club Award, Emory University School of Medicine, 2020
Best Doctors® 2006-2007
Senior Investigator Research Award, Crohn’s and Colitis Foundation of America
Junior Physician Investigator Award, American Federation for Medical Research