Wilbur Lam, MD, PhD

Research Program

Discovery and Developmental Therapeutics
Phone Number

404-727-7473
Email Address

wilbur.lam@emory.edu

Biography

Wilbur Lam, MD, PhD, is a professor and W. Paul Bowers Research Chair in the Department of Pediatrics and the Wallace H. Coulter Department of Biomedical Engineering at Emory University and Georgia Institute of Technology. Dr. Lam serves as associate dean of innovation for Emory University School of Medicine and as chief innovation officer for Children's Healthcare of Atlanta Pediatric Technology Center. He is also the inaugural vice provost for entrepreneurship for Emory University.

Dr. Lam is a member of the Discovery and Developmental Therapeutics Research Program at Winship Cancer Institute. He is a member of the National Academy of Medicine, a fellow of the American Institute for Medical and Biological Engineering, and an inductee of the American Society for Clinical Investigation.

Education

Dr. Lam earned his PhD in Bioengineering from the University of California, Berkeley. Prior to obtaining his PhD, Dr. Lam received his MD from Baylor College of Medicine. He completed his fellowship in Pediatric Hematology/Oncology and residency in Pediatrics at the University of California, San Francisco.

Titles & Roles

Professor, Division of Hematology/Oncology, Department of Pediatrics

Emory University School of Medicine
Professor and W. Paul Bowers Research Chair, Wallace H. Coulter Department of Biomedical Engineering

Georgia Institute of Technology and Emory University
Vice Provost for Entrepreneurship

Emory University
Associate Dean of Innovation

Emory University School of Medicine
Chief Innovation Officer, Pediatric Technology Center

Children’s Healthcare of Atlanta

Research

Dr. Lam's research interests involve developing and applying novel technologies using micro/nanotechnology, microfluidics, and cell mechanics to research, diagnose and treat hematologic and oncologic processes.

Grants

View Grants

Grant Number	Title
1R35HL145000-01	Engineering biophysical microtechnologies for hematologic applications in health and disease
2U54EB027690-06	Atlanta Center for Microsystems Engineered Point-of-Care Technologies (ACME POCT)
3U54EB027690-05S1	ACME POCT EMERGENCY COVID-19 VARIANT TESTING & INDEPENDENT TEST ASSESSMENT EVALUATION SUPPLEMENT
5R35HL145000-02	Engineering biophysical microtechnologies for hematologic applications in health and disease
5R35HL145000-03	Engineering biophysical microtechnologies for hematologic applications in health and disease
5R35HL145000-04	Engineering biophysical microtechnologies for hematologic applications in health and disease
5R35HL145000-05	Engineering biophysical microtechnologies for hematologic applications in health and disease
5R35HL145000-06	Engineering biophysical microtechnologies for hematologic applications in health and disease
5U54EB027690-07	Atlanta Center for Microsystems Engineered Point-of-Care Technologies (ACME POCT)

Publications

Title/Journal	Authors	Publication Date
High-throughput quantitation of human neutrophil recruitment and functional responses in an air-blood barrier array. APL bioengineering	H Viola, LH Chen, S Jo, K Washington, C Selva, A Li, D Feng, V Giacalone, ST Stephenson, K Cottrill, A Mohammad, E Williams, X Qu, W Lam, NL Ng, A Fitzpatrick, J Grunwell, R Tirouvanziam, S Takayama	06/01/2025
From Lab-on-a-Chip to Lab-on-a-Chip-in-the-Lab: a perspective of clinical laboratory medicine for the microtechnologist. Lab on a chip	K Fibben, EK Williams, JD Roback, WA Lam, DN Alter	05/28/2025
Real-world implementation of a noninvasive, AI-augmented, anemia-screening smartphone app and personalization for hemoglobin level self-monitoring. Proceedings of the National Academy of Sciences of the United States of America	RG Mannino, J Sullivan, JK Frediani, P George, J Whitson, J Tumlin, LA Lyon, EA Tyburski, WA Lam	05/20/2025
Multi-niche human bone marrow on-a-chip for studying the interactions of adoptive CAR-T cell therapies with multiple myeloma. Biomaterials	D Ghoshal, I Petersen, R Ringquist, L Kramer, E Bhatia, T Hu, A Richard, R Park, J Corbin, S Agarwal, A Thomas, S Ramirez, J Tharayil, E Downey, F Ketchum, A Ochal, N Sonthi, S Lonial, JN Kochenderfer, R Tran, M Zhu, WA Lam, AF Coskun, K Roy	05/01/2025
Clinically relevant clot resolution via a thromboinflammation-on-a-chip. Nature	Y Qiu, J Lin, A Wang, Z Fang, Y Sakurai, H Choi, EK Williams, ET Hardy, K Maher, AF Coskun, G Woods, WA Lam	05/01/2025
Evaluating the Long-Term Benefits of Hydroxyurea in Pediatric Sickle Cell Anemia. Blood advances	PE George, GG Kalmus, PA Lane, WA Lam, J Lipscomb, D Howard	04/16/2025
Non - Invasive, smartphone image-based screening for sickle cell disease at the point-of-need. Heliyon	EF Vital, MH LiCalzi, RG Mannino, PT McGann, WA Lam	01/30/2025
Redefining the role of near-peer student volunteers in children's hospitals as paediatric patient mentors. Archives of disease in childhood	ET Hardy, WA Lam	01/24/2025
The Shift to Over-the-Counter Diagnostic Testing After RADx: Clinical, Regulatory, and Societal Implications. IEEE open journal of engineering in medicine and biology	M Downing, J Broach, W Lam, YC Manabe, G Martin, D McManus, R Murphy, A Soni, S Schachter	01/01/2025
Recommendations for defining disturbed flow as laminar, transitional, or turbulent in assays of hemostasis and thrombosis: communication from the ISTH SSC Subcommittee on Biorheology. Journal of thrombosis and haemostasis : JTH	DL Bark, EF Vital, C Oury, WA Lam, EE Gardiner	01/01/2025
Viral and host factors associated with SARS-CoV-2 disease severity in Georgia, USA. PloS one	LR Carmola, AD Roebling, D Khosravi, RM Langsjoen, A Bombin, B Bixler, A Reid, C Chen, E Wang, Y Lu, Z Zheng, R Zhang, PV Nguyen, RA Arthur, E Fitts, DA Gulick, D Higginbotham, A Taz, A Ahmed, JH Crumpler, C Kraft, WA Lam, A Babiker, JJ Waggoner, KP Openo, LM Johnson, A Westbrook, A Piantadosi	01/01/2025
Autoantibodies immuno-mechanically modulate platelet contractile force and bleeding risk. Nature communications	O Oshinowo, R Copeland, A Patel, N Shaver, ME Fay, R Jeltuhin, Y Xiang, C Caruso, AE Otumala, S Hernandez, P Delgado, G Dean, JM Kelvin, D Chester, AC Brown, EC Dreaden, T Leong, J Waggoner, R Li, E Ortlund, C Bennett, WA Lam, DR Myers	11/25/2024
Less-deformable erythrocyte subpopulations biomechanically induce endothelial inflammation in sickle cell disease. Blood	C Caruso, X Cheng, ME Michaud, HM Szafraniec, BE Thomas, ME Fay, RG Mannino, X Zhang, Y Sakurai, W Li, DR Myers, CH Joiner, DK Wood, M Bhasin, MD Graham, WA Lam	11/07/2024
Red blood cells: more than bags of hemoglobin. Blood	CL Maier, WA Lam	10/03/2024
Diagnostic Utility of SARS-CoV-2 Nucleocapsid Antigenemia: A Meta-analysis. Open forum infectious diseases	GL Damhorst, SE Martin, E Wilber, H Verkerke, M Goodman, WA Lam	10/01/2024
PPARγ/ETV2 axis regulates endothelial-to-mesenchymal transition in pulmonary hypertension. Pulmonary circulation	DH Lee, M Kim, SS Chang, R Lee, AJ Jang, J Kim, J Ma, MJ Passineau, RL Benza, H Karmouty-Quintana, WA Lam, BT Kopp, RL Sutliff, CM Hart, C Park, BY Kang	10/01/2024
Protocol for the creation and characterization of SARS-CoV-2 variant testing panels using remnant clinical samples for diagnostic assay testing. STAR protocols	L Bassit, HB Bowers, M Greenleaf, C Sabino, E Lai, G Yu, A Piantadosi, E Wang, W O'Sick, K McLendon, JA Sullivan, RF Schinazi, GL Damhorst, W Lam, A Rao	09/20/2024
Respiratory virus detection and sequencing from negative SARS-CoV-2 rapid antigen tests. medRxiv : the preprint server for health sciences	E Jules, C Decker, BJ Bixler, A Ahmed, ZC Zhou, I Arora, H Tafesse, H Dakanay, A Bombin, E Wang, J Ingersoll, K Bifulco, JK Frediani, R Parsons, J Sullivan, M Greenleaf, JJ Waggoner, GS Martin, WA Lam, A Piantadosi	08/20/2024
BiliQML: a supervised machine-learning model to quantify biliary forms from digitized whole slide liver histopathological images. American journal of physiology. Gastrointestinal and liver physiology	DJ Hellen, ME Fay, DH Lee, C Klindt-Morgan, A Bennett, KJ Pachura, A Grakoui, SS Huppert, PA Dawson, WA Lam, SJ Karpen	07/01/2024
Total Synthesis of a PSGL-1 Glycopeptide Analogue for Targeted Inhibition of P-Selectin. Journal of the American Chemical Society	B Dhakal, A Mandhapati, P Eradi, S Park, K Fibben, K Li, A DeYong, S Escopy, G Karki, DD Park, CA Haller, E Dai, L Sun, WA Lam, EL Chaikof	06/26/2024
Redefining hyperviscosity in acute leukemia: Potential implications for red cell transfusions in the microvasculature. American journal of hematology	JO Musick, EK Williams, KS Fibben, DY Zhang, C Caruso, Y Sakurai, R Tran, ML Kemp, WA Lam	06/01/2024
Bridging the Divide: Unintended Consequences of the Shift to Home-Based Telemedicine. The Journal of pediatrics	PE George, D Kc, M Greenleaf, J Shah, WA Lam, CM Hawkins	06/01/2024
HIGH THROUGHPUT QUANTITATION OF HUMAN NEUTROPHIL RECRUITMENT AND FUNCTIONAL RESPONSES IN AN AIR-BLOOD BARRIER ARRAY. bioRxiv : the preprint server for biology	H Viola, LH Chen, S Jo, K Washington, C Selva, A Li, D Feng, V Giacalone, ST Stephenson, K Cottrill, A Mohammed, E Williams, X Qu, W Lam, NL Ng, A Fitzpatrick, J Grunwell, R Tirouvanziam, S Takayama	05/14/2024
Multi-Niche Human Bone Marrow On-A-Chip for Studying the Interactions of Adoptive CAR-T Cell Therapies with Multiple Myeloma. bioRxiv : the preprint server for biology	D Ghoshal, I Petersen, R Ringquist, L Kramer, E Bhatia, T Hu, A Richard, R Park, J Corbin, S Agarwal, A Thomas, S Ramirez, J Tharayil, E Downey, F Ketchum, A Ochal, N Sonthi, S Lonial, JN Kochenderfer, R Tran, M Zhu, WA Lam, AF Coskun, K Roy	04/12/2024
Performance of the Xpert™ Mpox PCR assay with oropharyngeal, anorectal, and cutaneous lesion swab specimens. Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology	GL Damhorst, K McLendon, E Morales, ZM Solis, E Fitts, HB Bowers, C Sabino, J Sullivan, M Greenleaf, JD Roback, JA Colasanti, AN Sheth, BK Titanji, GS Martin, L Bassit, WA Lam, A Rao	04/01/2024
Comparison of RT-PCR and antigen test sensitivity across nasopharyngeal, nares, and oropharyngeal swab, and saliva sample types during the SARS-CoV-2 omicron variant. Heliyon	GL Damhorst, J Lin, JK Frediani, JA Sullivan, A Westbrook, K McLendon, TJ Baugh, WH O'Sick, JD Roback, AL Piantadosi, JJ Waggoner, L Bassit, A Rao, M Greenleaf, JW O'Neal, S Swanson, NR Pollock, GS Martin, WA Lam, JM Levy	03/30/2024
Next generation microfluidics: fulfilling the promise of lab-on-a-chip technologies. Lab on a chip	UA Gurkan, DK Wood, D Carranza, LH Herbertson, SL Diamond, E Du, S Guha, J Di Paola, PC Hines, I Papautsky, SS Shevkoplyas, NJ Sniadecki, VK Pamula, P Sundd, A Rizwan, P Qasba, WA Lam	03/26/2024
Multisite Mpox Infection and Viral Dynamics Among Persons With HIV in Metro Atlanta. The Journal of infectious diseases	GL Damhorst, AW Fujita, E Fitts, B Szabo, HB Bowers, C Sabino, A Ahmed, E Wang, A Piantadosi, K McLendon, J Sullivan, M Greenleaf, D McCaslin, M Palmore, AM Anderson, B Aldred, C Gunthel, GS Martin, JA Colasanti, WA Lam, L Bassit, A Rao, AN Sheth, BK Titanji	03/26/2024
What's in a Name? Experimental Evidence of Gender Bias in Recommendation Letters Generated by ChatGPT. Journal of medical Internet research	DM Kaplan, R Palitsky, SJ Arconada Alvarez, NS Pozzo, MN Greenleaf, CA Atkinson, WA Lam	03/05/2024
The New Normal: Delayed Peak SARS-CoV-2 Viral Loads Relative to Symptom Onset and Implications for COVID-19 Testing Programs. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America	JK Frediani, R Parsons, KB McLendon, AL Westbrook, W Lam, G Martin, NR Pollock	02/17/2024
Engaging Cancer Care Physicians in Off-Label Drug Clinical Trials: Human-Centered Design Approach. JMIR formative research	MC Parsell, MN Greenleaf, GG Kombara, VP Sukhatme, WA Lam	02/15/2024
Challenges and Opportunities for Commercializing Technologies in the Pulmonary Arena: An Official American Thoracic Society Report. Annals of the American Thoracic Society	M Vukmirovic, KH Benam, JJ Rose, S Turner, CM Magin, D Lagares, AH Cohen, N Kaminski, JA Hirota, TM Maher, M Konigshoff, RK Mallampalli, D Sheppard, R Tarran, RH Gomer, NJ Kenyon, D Morris, S Hobbie, SV Raju, I Petrache, T Watkins, R Kumar, WA Lam, T Sherer, L Hecker	01/01/2024
"An app is just available at all times"-the process and outcomes of converting the Georgia Tuberculosis Reference Guide into a mobile application. PloS one	SJ Arconada Alvarez, AT Hoover, M Greenleaf, SM Ray, MC Schechter, HM Blumberg, WA Lam	01/01/2024
Hemostasis-on-a-chip / incorporating the endothelium in microfluidic models of bleeding. Platelets	Y Sakurai, ET Hardy, WA Lam	12/01/2023
Marginated aberrant red blood cells induce pathologic vascular stress fluctuations in a computational model of hematologic disorders. Science advances	X Cheng, C Caruso, WA Lam, MD Graham	12/01/2023
Rapid, high throughput, automated detection of SARS-CoV-2 neutralizing antibodies against Wuhan-WT, delta and omicron BA1, BA2 spike trimers. iScience	N Cheedarla, HP Verkerke, S Potlapalli, KB McLendon, A Patel, F Frank, WH O'Sick, S Cheedarla, TJ Baugh, GL Damhorst, H Wu, D Graciaa, F Hudaib, DN Alter, J Bryksin, EA Ortlund, J Guarner, S Auld, S Shah, W Lam, D Mattoon, JM Johnson, DH Wilson, MV Dhodapkar, SR Stowell, AS Neish, JD Roback	11/17/2023
Standardization and Comparison of Emergency Use Authorized COVID-19 Assays and Testing Laboratories. medRxiv : the preprint server for health sciences	A Rao, J Lin, R Parsons, M Greenleaf, A Westbrook, E Lai, HB Bowers, K McClendon, W O'Sick, T Baugh, M Sifford, JA Sullivan, WA Lam, L Bassit	11/08/2023
Probing interactions of red blood cells and contracting fibrin platelet clots. Biophysical journal	Y Sun, H Le, WA Lam, A Alexeev	11/07/2023
Viral and host factors associated with SARS-CoV-2 disease severity in Georgia, USA. medRxiv : the preprint server for health sciences	LR Carmola, AD Roebling, D Khosravi, RM Langsjoen, A Bombin, B Bixler, A Reid, C Chen, E Wang, Y Lu, Z Zheng, R Zhang, PV Nguyen, RA Arthur, E Fitts, DA Gulick, D Higginbotham, A Taz, A Ahmed, JH Crumpler, C Kraft, WA Lam, A Babiker, JJ Waggoner, KP Openo, LM Johnson, A Westbrook, A Piantadosi	10/25/2023
Sensitivity of rapid antigen tests against SARS-CoV-2 Omicron and Delta variants. Journal of clinical microbiology	A Rao, A Westbrook, L Bassit, R Parsons, E Fitts, M Greenleaf, K McLendon, JA Sullivan, W O'Sick, T Baugh, HB Bowers, F Frank, E Wang, M Le, J Frediani, P Roychoudhury, AL Greninger, R Jerris, NR Pollock, EA Ortlund, JD Roback, WA Lam, A Piantadosi	10/24/2023
A novel mobile health application to support cancer surveillance needs of patients and families with cancer predisposition syndromes. Pediatric blood & cancer	SJA Alvarez, B Pencheva, E Westfall, C Mwalija, M Parsell, M Greenleaf, CC Porter, WA Lam, RG Mannino, SG Mitchell	10/01/2023
Label-free microfluidic isolation of functional and viable lymphocytes from peripheral blood mononuclear cells. Biomicrofluidics	A Raj, K Ramirez, KM Young, N Stone, P Shankles, MNR Ali, AM Compton, W Lam, A Alexeev, T Sulchek	09/01/2023
Prevalence of SARS-CoV-2 in hemoglobinopathies is modified by age and race. Blood cells, molecules & diseases	JK Frediani, E Pak-Harvey, R Parsons, AL Westbrook, W O'Sick, GS Martin, WA Lam, JM Levy	09/01/2023
Development of constitutively synergistic nanoformulations to enhance chemosensitivity in T-cell leukemia. Journal of controlled release : official journal of the Controlled Release Society	JM Kelvin, ML Chimenti, DY Zhang, EK Williams, SG Moore, GM Humber, TA Baxter, LA Birnbaum, M Qui, H Zecca, A Thapa, J Jain, NT Jui, X Wang, H Fu, Y Du, ML Kemp, WA Lam, DK Graham, D DeRyckere, EC Dreaden	09/01/2023
Why platelet mechanotransduction matters for hemostasis and thrombosis. Journal of thrombosis and haemostasis : JTH	O Oshinowo, SS Azer, J Lin, WA Lam	09/01/2023
Wear With Care: A Call for Empirical Investigations of Adverse Outcomes of Consumer Health Wearables. Mayo Clinic proceedings. Digital health	DM Kaplan, M Greenleaf, WA Lam	09/01/2023
Respiratory Coinfections in Children With SARS-CoV-2. The Pediatric infectious disease journal	A Westbrook, T Wang, K Bhakta, J Sullivan, MD Gonzalez, W Lam, CA Rostad	09/01/2023
iCLOTS: open-source, artificial intelligence-enabled software for analyses of blood cells in microfluidic and microscopy-based assays. Nature communications	ME Fay, O Oshinowo, E Iffrig, KS Fibben, C Caruso, S Hansen, JO Musick, JM Valdez, SS Azer, RG Mannino, H Choi, DY Zhang, EK Williams, EN Evans, CK Kanne, ML Kemp, VA Sheehan, MA Carden, CM Bennett, DK Wood, WA Lam	08/18/2023
Blood Coagulation and Beyond: Position Paper from the Fourth Maastricht Consensus Conference on Thrombosis. Thrombosis and haemostasis	AC Akbulut, RA Arisz, CCFMJ Baaten, G Baidildinova, A Barakzie, R Bauersachs, J Ten Berg, WWA van den Broek, HC de Boer, A Bonifay, V Bröker, RJ Buka, H Ten Cate, AJ Ten Cate-Hoek, S Cointe, C De Luca, I De Simone, RV Diaz, F Dignat-George, K Freson, G Gazzaniga, ECM van Gorp, A Habibi, YMC Henskens, AFJ Iding, A Khan, GH Koenderink, A Konkoth, R Lacroix, T Lahiri, W Lam, RE Lamerton, R Lorusso, Q Luo, C Maas, OJT McCarty, PEJ van der Meijden, JCM Meijers, AK Mohapatra, N Nevo, AP Robles, P Poncelet, C Reinhardt, W Ruf, R Saraswat, C Schönichen, R Schutgens, P Simioni, S Spada, HMH Spronk, K Tazhibayeva, J Thachil, RV Diaz, L Vallier, A Veninga, P Verhamme, C Visser, SP Watson, P Wenzel, RAL Willems, A Willers, P Zhang, K Zifkos, AJ van Zonneveld	08/01/2023
Are children with sickle cell disease at particular risk from the harmful effects of air pollution? Evidence from a large, urban/peri-urban cohort. Pediatric blood & cancer	PE George, A Maillis, Y Zhu, Y Liu, PA Lane, W Lam, J Lipscomb, S Ebelt	05/29/2023
Marginated aberrant red blood cells induce pathologic vascular stress fluctuations in a computational model of hematologic disorders. bioRxiv : the preprint server for biology	X Cheng, C Caruso, WA Lam, MD Graham	05/18/2023
Pivot, persevere, or perish: how Ellume Health overcame development and regulatory obstacles to become the first authorized over-the-counter COVID-19 test in the United States. Lab on a chip	MN Greenleaf, E Nehl, GL Damhorst, WA Lam	05/16/2023
The New Normal: Delayed Peak SARS-CoV-2 Viral Loads Relative to Symptom Onset and Implications for COVID-19 Testing Programs. medRxiv : the preprint server for health sciences	JK Frediani, R Parsons, KB McLendon, AL Westbrook, W Lam, G Martin, NR Pollock	05/10/2023
Hidden behind thromboinflammation: revealing the roles of von Willebrand factor in sickle cell disease pathophysiology. Current opinion in hematology	EF Vital, WA Lam	05/01/2023
SARS-CoV-2 molecular testing and whole genome sequencing following RNA recovery from used BinaxNOW COVID-19 antigen self tests. Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology	PV Nguyen, LR Carmola, E Wang, L Bassit, A Rao, M Greenleaf, JA Sullivan, GS Martin, WA Lam, JJ Waggoner, A Piantadosi	05/01/2023
Investigation of Blood Plasma Viral Nucleocapsid Antigen as a Marker of Active Severe Acute Respiratory Syndrome Coronavirus 2 Omicron Variant Infection. Open forum infectious diseases	GL Damhorst, N Schoof, PV Nguyen, H Verkerke, E Wilber, K McLendon, W O'Sick, T Baugh, S Cheedarla, N Cheedarla, V Stittleburg, EC Fitts, MA Neja, A Babiker, A Piantadosi, JD Roback, JJ Waggoner, M Mavigner, WA Lam	05/01/2023
The critical role of engineering in the rapid development of COVID-19 diagnostics: Lessons from the RADx Tech Test Verification Core. Science advances	RG Mannino, EJ Nehl, S Farmer, AF Peagler, MC Parsell, V Claveria, D Ku, DS Gottfried, H Chen, WA Lam, O Brand	04/07/2023
Multiplatform analyses reveal distinct drivers of systemic pathogenesis in adult versus pediatric severe acute COVID-19. Nature communications	S Druzak, E Iffrig, BR Roberts, T Zhang, KS Fibben, Y Sakurai, HP Verkerke, CA Rostad, A Chahroudi, F Schneider, AKH Wong, AM Roberts, JD Chandler, SO Kim, M Mosunjac, M Mosunjac, R Geller, I Albizua, SR Stowell, CM Arthur, EJ Anderson, AA Ivanova, J Ahn, X Liu, K Maner-Smith, T Bowen, M Paiardini, SE Bosinger, JD Roback, DA Kulpa, G Silvestri, WA Lam, EA Ortlund, CL Maier	04/04/2023
Navigating the complexities of mobile medical app development from idea to launch, a guide for clinicians and biomedical researchers. BMC medicine	RG Mannino, SJ Arconada Alvarez, M Greenleaf, M Parsell, C Mwalija, WA Lam	03/23/2023
Compact and low-cost deep-ultraviolet microscope system for label-free molecular imaging and point-of-care hematological analysis. Biomedical optics express	V Gorti, N Kaza, EK Williams, WA Lam, FE Robles	03/01/2023
Sensitivity of Rapid Antigen Tests Against SARS-CoV-2 Omicron and Delta Variants. medRxiv : the preprint server for health sciences	A Rao, A Westbrook, L Bassit, R Parsons, E Fitts, M Greenleaf, K McLendon, JA Sullivan, W O'Sick, T Baugh, HB Bowers, F Frank, E Wang, M Le, J Frediani, P Roychoudhury, AL Greninger, R Jerris, NR Pollock, EA Ortlund, JD Roback, WA Lam, A Piantadosi	02/10/2023
SARS-CoV-2 Results in Self-collected Nasal Swabs vs Swabs Collected by Health Care Workers in Children and Adolescents-Reply. JAMA	JJ Waggoner, EA Tyburski, WA Lam	02/07/2023
Current challenges and future directions for engineering extracellular vesicles for heart, lung, blood and sleep diseases. Journal of extracellular vesicles	G Li, T Chen, J Dahlman, L Eniola-Adefeso, IC Ghiran, P Kurre, WA Lam, JK Lang, E Marbán, P Martín, S Momma, M Moos, DJ Nelson, RL Raffai, X Ren, JPG Sluijter, SL Stott, G Vunjak-Novakovic, ND Walker, Z Wang, KW Witwer, PC Yang, MS Lundberg, MJ Ochocinska, R Wong, G Zhou, SY Chan, S Das, P Sundd	02/01/2023
SARS-CoV-2 Antigenemia is Associated With Pneumonia in Children But Lacks Sensitivity to Diagnose Acute Infection. The Pediatric infectious disease journal	GL Damhorst, HP Verkerke, KRV Harrington, K McLendon, A Lu, MA Perez, L Hussaini, EJ Anderson, SR Stowell, JD Roback, WA Lam, CA Rostad	02/01/2023
Membrane curvature and PS localize coagulation proteins to filopodia and retraction fibers of endothelial cells. Blood advances	CV Carman, DN Nikova, Y Sakurai, J Shi, VA Novakovic, JT Rasmussen, WA Lam, GE Gilbert	01/10/2023
SARS-CoV-2 molecular testing and whole genome sequencing following RNA recovery from used BinaxNOW COVID-19 Antigen Self Tests. medRxiv : the preprint server for health sciences	PV Nguyen, LR Carmola, E Wang, L Bassit, A Rao, M Greenleaf, JA Sullivan, GS Martin, WA Lam, JJ Waggoner, A Piantadosi	01/09/2023
Complement inhibition can decrease the haemostatic response in a microvascular bleeding model at multiple levels. Frontiers in immunology	M Golomingi, J Kohler, C Lamers, RB Pouw, D Ricklin, J Dobó, P Gál, G Pál, B Kiss, A Dopler, CQ Schmidt, ET Hardy, W Lam, V Schroeder	01/01/2023
Effect of swab pooling on the Accula point-of-care RT-PCR for SARS-CoV-2 detection. Frontiers in microbiology	M Lancelot, K Fibben, J Sullivan, W O'Sick, K McLendon, H Wu, A Rao, LC Bassit, M Greenleaf, P Miller, W Krull, E Tyburski, JD Roback, WA Lam, GL Damhorst	01/01/2023
Lessons Learned from In-Person Conferences in the Times of COVID-19. International journal of environmental research and public health	M Ehteshami, CL Edgar, LY Delgado Ayala, M Hagan, GS Martin, W Lam, RF Schinazi	12/28/2022
Label-free deep-UV microscopy detection and grading of neutropenia using a passive microfluidic device. Optics letters	A Ojaghi, E Kendall Williams, N Kaza, V Gorti, H Choi, J Torey, T Wiley, B Turner, S Jackson, S Park, WA Lam, FE Robles	11/15/2022
Hyperviscosity syndromes; hemorheology for physicians and the use of microfluidic devices. Current opinion in hematology	JO Musick, KS Fibben, WA Lam	11/01/2022
Subgenomic RNA Abundance Relative to Total Viral RNA Among Severe Acute Respiratory Syndrome Coronavirus 2 Variants. Open forum infectious diseases	M Su, S Ping, PV Nguyen, A Rojas, L Hussaini, LR Carmola, A Taz, J Sullivan, GS Martin, A Piantadosi, M Martinez, WA Lam, EJ Anderson, JJ Waggoner	11/01/2022
Nucleocapsid Antigenemia Is a Marker of Acute SARS-CoV-2 Infection. The Journal of infectious diseases	HP Verkerke, GL Damhorst, DS Graciaa, K McLendon, W O'Sick, C Robichaux, N Cheedarla, S Potlapalli, SC Wu, KRV Harrington, A Webster, C Kraft, CA Rostad, JJ Waggoner, NR Gandhi, J Guarner, SC Auld, A Neish, JD Roback, WA Lam, NS Shah, SR Stowell	11/01/2022
Predictive Value of Isolated Symptoms for Diagnosis of Severe Acute Respiratory Syndrome Coronavirus 2 Infection in Children Tested During Peak Circulation of the Delta Variant. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America	AL Westbrook, LC Benedit, JK Frediani, MA Griffiths, NY Khan, JM Levy, CR Morris, CA Rostad, CL Stone, J Sullivan, MB Vos, J Welsh, A Wood, GS Martin, W Lam, NR Pollock	09/30/2022
Deep mutational scanning identifies SARS-CoV-2 Nucleocapsid escape mutations of currently available rapid antigen tests. Cell	F Frank, MM Keen, A Rao, L Bassit, X Liu, HB Bowers, AB Patel, ML Cato, JA Sullivan, M Greenleaf, A Piantadosi, WA Lam, WH Hudson, EA Ortlund	09/15/2022
Concordance of SARS-CoV-2 Results in Self-collected Nasal Swabs vs Swabs Collected by Health Care Workers in Children and Adolescents. JAMA	JJ Waggoner, MB Vos, EA Tyburski, PV Nguyen, JM Ingersoll, C Miller, J Sullivan, M Griffiths, C Stone, M Benoit, L Benedit, B Seitter, R Jerris, JM Levy, CS Kraft, S Farmer, A Peagler, A Wood, AL Westbrook, CR Morris, UN Sathian, W Heetderks, L Li, K Roth, M Barcus, T Stenzel, GS Martin, WA Lam	09/13/2022
Comparison of Mid-turbinate Nasal Swabs, Saliva, and Nasopharyngeal Swabs for SARS-CoV-2 Reverse Transcription-Polymerase Chain Reaction Testing in Pediatric Outpatients. Archives of pathology & laboratory medicine	MB Vos, MD Gonzalez, C Stone, R Cleeton, J Figueroa, R Jerris, SI Park, S Heilman, R Nayee, A Chahroudi, N Schoof, M Mavigner, CR Morris, T Leong, A Grindle, A Westbrook, W Lam, BB Rogers	09/01/2022
Nucleocapsid Antigenemia in Patients Receiving Anti-CD20 Therapy With Protracted COVID-19. Open forum infectious diseases	E Wilber, A Piantadosi, A Babiker, K McLendon, W O'Sick, E Fitts, AS Webster, H Verkerke, JS Kim, VK Phadke, N Rouphael, BK Titanji, WT Blake, J Howard-Anderson, JD Roback, WA Lam, GL Damhorst	08/01/2022
Microfluidic methods to advance mechanistic understanding and translational research in sickle cell disease. Translational research : the journal of laboratory and clinical medicine	M Azul, EF Vital, WA Lam, DK Wood, JD Beckman	08/01/2022
Pathologic mechanobiological interactions between red blood cells and endothelial cells directly induce vasculopathy in iron deficiency anemia. iScience	C Caruso, ME Fay, X Cheng, AY Liu, SI Park, TA Sulchek, MD Graham, WA Lam	07/15/2022
Don't forget about human factors: Lessons learned from COVID-19 point-of-care testing. Cell reports methods	S Farmer, V Razin, AF Peagler, S Strickler, WB Fain, GL Damhorst, RR Kempker, NR Pollock, O Brand, B Seitter, SS Heilman, EJ Nehl, JM Levy, DS Gottfried, GS Martin, M Greenleaf, DN Ku, JJ Waggoner, E Iffrig, RG Mannino, Y F Wang, E Ortlund, J Sullivan, PA Rebolledo, V Clavería, JD Roback, M Benoit, C Stone, A Esper, F Frank, WA Lam	05/23/2022
Designing for simplicity: lessons from Mesa Biotech for microfluidic entrepreneurs and early-stage companies. Lab on a chip	MN Greenleaf, GL Damhorst, DN Ku, EJ Nehl, EA Tyburski, O Brand, GS Martin, WA Lam	04/12/2022
Feature tracking microfluidic analysis reveals differential roles of viscosity and friction in sickle cell blood. Lab on a chip	HM Szafraniec, JM Valdez, E Iffrig, WA Lam, JM Higgins, P Pearce, DK Wood	04/12/2022
Building the foundation of health-related knowledge via near-peer education for children with sickle cell disease. Pediatric blood & cancer	ELT Hardy, B Williams, C Harden, O Oshinowo, R Copeland, MA Carden, BE Gee, WA Lam	04/01/2022
Assessment of the Abbott BinaxNOW SARS-CoV-2 rapid antigen test against viral variants of concern. iScience	A Rao, L Bassit, J Lin, K Verma, HB Bowers, K Pachura, M Greenleaf, J Sullivan, E Lai, RS Creager, T Pribyl, J Blackwood, AL Piantadosi, R Schinazi, GS Martin, WA Lam	03/18/2022
Rapid, high throughput, automated detection of SARS-CoV-2 neutralizing antibodies against native-like vaccine and delta variant spike trimers. Research square	N Cheedarla, HP Verkerke, S Potlapalli, KB McLendon, A Patel, F Frank, GL Damhorst, H Wu, WH O'Sick, D Graciaa, F Hudaib, DN Alter, J Bryksin, EA Ortlund, J Guarner, S Auld, S Shah, W Lam, D Mattoon, JM Johnson, DH Wilson, MV Dhodapkar, SR Stowell, AS Neish, JD Roback	02/16/2022
Where is Omicron? Comparison of SARS-CoV-2 RT-PCR and Antigen Test Sensitivity at Commonly Sampled Anatomic Sites Over the Course of Disease. medRxiv : the preprint server for health sciences	J Lin, JK Frediani, GL Damhorst, JA Sullivan, A Westbrook, K McLendon, TJ Baugh, WH O'Sick, JD Roback, AL Piantadosi, JJ Waggoner, L Bassit, A Rao, M Greenleaf, JW O'Neal, S Swanson, NR Pollock, GS Martin, WA Lam, JM Levy	02/09/2022
Rapid, high throughput, automated detection of SARS-CoV-2 neutralizing antibodies against native-like vaccine and delta variant spike trimers. medRxiv : the preprint server for health sciences	N Cheedarla, HP Verkerke, S Potlapalli, KB McLendon, A Patel, F Frank, GL Damhorst, H Wu, WH Oâ Sick, D Graciaa, F Hudaib, DN Alter, J Bryksin, EA Ortlund, J Guarner, S Auld, S Shah, W Lam, D Mattoon, JM Johnson, DH Wilson, MV Dhodapkar, SR Stowell, AS Neish, JD Roback	02/02/2022
Clinical evaluation of the Diagnostic Analyzer for Selective Hybridization (DASH): a point-of-care PCR test for rapid detection of SARS-CoV-2 infection. medRxiv : the preprint server for health sciences	CJ Achenbach, M Caputo, C Hawkins, LC Balmert, C Qi, J Odorisio, E Dembele, A Jackson, H Abbas, JK Frediani, JM Levy, PA Rebolledo, RR Kempker, AM Esper, WA Lam, GS Martin, RL Murphy	01/25/2022
Resolving the missing link between single platelet force and clot contractile force. iScience	Y Sun, O Oshinowo, DR Myers, WA Lam, A Alexeev	01/21/2022
High-Throughput On-Chip Human Mesenchymal Stromal Cell Potency Prediction. Advanced healthcare materials	RS Schneider, AC Vela, EK Williams, KE Martin, WA Lam, AJ García	01/01/2022
Complement lectin pathway components MBL and MASP-1 promote haemostasis upon vessel injury in a microvascular bleeding model. Frontiers in immunology	M Golomingi, J Kohler, L Jenny, ET Hardy, J Dobó, P Gál, G Pál, B Kiss, WA Lam, V Schroeder	01/01/2022
Severe acute respiratory syndrome coronavirus 2 vaccine breakthrough infections: A single metro-based testing network experience. Frontiers in medicine	SS Strickler, A Esper, L Wells, A Wood, JK Frediani, E Nehl, JJ Waggoner, PA Rebolledo, JM Levy, J Figueroa, T Ramachandra, W Lam, GS Martin	01/01/2022
Miniaturized Vascularized Bleeding Model of Hemostasis. Methods in molecular biology (Clifton, N.J.)	ET Hardy, Y Sakurai, WA Lam	01/01/2022
Clinical evaluation of the Diagnostic Analyzer for Selective Hybridization (DASH): A point-of-care PCR test for rapid detection of SARS-CoV-2 infection. PloS one	CJ Achenbach, M Caputo, C Hawkins, LC Balmert, C Qi, J Odorisio, E Dembele, A Jackson, H Abbas, JK Frediani, JM Levy, PA Rebolledo, RR Kempker, AM Esper, WA Lam, GS Martin, RL Murphy	01/01/2022
SARS-CoV-2 reliably detected in frozen saliva samples stored up to one year. PloS one	JK Frediani, KB McLendon, A Westbrook, SE Gillespie, A Wood, TJ Baugh, W O'Sick, JD Roback, WA Lam, JM Levy	01/01/2022
Single-Amplicon Multiplex Real-Time Reverse Transcription-PCR with Tiled Probes To Detect SARS-CoV-2 spike Mutations Associated with Variants of Concern. Journal of clinical microbiology	A Babiker, K Immergluck, SD Stampfer, A Rao, L Bassit, M Su, V Nguyen, V Stittleburg, JM Ingersoll, HL Bradley, M Mavigner, N Schoof, CS Kraft, A Chahroudi, RF Schinazi, GS Martin, A Piantadosi, WA Lam, JJ Waggoner	11/18/2021
Correlation of SARS-CoV-2 Subgenomic RNA with Antigen Detection in Nasal Midturbinate Swab Specimens. Emerging infectious diseases	K Immergluck, MD Gonzalez, JK Frediani, JM Levy, J Figueroa, A Wood, BB Rogers, J O'Neal, R Elias-Marcellin, A Suessmith, J Sullivan, RF Schinazi, A Babiker, A Piantadosi, MB Vos, GS Martin, WA Lam, JJ Waggoner	11/01/2021
Pathologically stiff erythrocytes impede contraction of blood clots: Reply to comment. Journal of thrombosis and haemostasis : JTH	V Tutwiler, RI Litvinov, A Protopopova, C Nagaswami, C Villa, E Woods, O Abdulmalik, DL Siegel, JE Russell, VR Muzykantov, WA Lam, DR Myers, JW Weisel	11/01/2021
Label-free automated neutropenia detection and grading using deep-ultraviolet microscopy. Biomedical optics express	A Ojaghi, P Casteleiro Costa, C Caruso, WA Lam, FE Robles	10/01/2021
Dosage-dependent antimicrobial activity of DNA-histone microwebs against Staphylococcus aureus. Advanced materials interfaces	T Yang, S Yang, T Ahmed, K Nguyen, J Yu, X Cao, R Zan, X Zhang, H Shen, ME Fay, EK Williams, WA Lam, JS VanEpps, S Takayama, Y Song	09/09/2021
The need for new test verification and regulatory support for innovative diagnostics. Nature biotechnology	JD Roback, EA Tyburski, D Alter, S Asakrah, A Chahroudi, A Esper, S Farmer, J Figueroa, J K Frediani, M D Gonzalez, D S Gottfried, J Guarner, N A Gupta, S S Heilman, C E Hill, R Jerris, R R Kempker, J Ingersoll, JM Levy, M Mavigner, C S Moreno, C R Morris, E J Nehl, A S Neish, D Peker, N Saakadze, PA Rebolledo, C A Rostad, N Schoof, A Suessmith, J Sullivan, YFW Wang, A Wood, MB Vos, O Brand, GS Martin, WA Lam	09/01/2021
Pathologically stiff erythrocytes impede contraction of blood clots. Journal of thrombosis and haemostasis : JTH	V Tutwiler, RI Litvinov, A Protopopova, C Nagaswami, C Villa, E Woods, O Abdulmalik, DL Siegel, JE Russell, VR Muzykantov, WA Lam, DR Myers, JW Weisel	08/01/2021
Impact of repeated nasal sampling on detection and quantification of SARS-CoV-2. Scientific reports	JM Levy, JK Frediani, EA Tyburski, A Wood, J Figueroa, RR Kempker, PA Rebolledo, MD Gonzalez, J Sullivan, MB Vos, J O'Neal, GS Martin, WA Lam, JJ Waggoner	07/21/2021
Multidisciplinary assessment of the Abbott BinaxNOW SARS-CoV-2 point-of-care antigen test in the context of emerging viral variants and self-administration. Scientific reports	JK Frediani, JM Levy, A Rao, L Bassit, J Figueroa, MB Vos, A Wood, R Jerris, null Van Leung-Pineda, MD Gonzalez, BB Rogers, M Mavigner, RF Schinazi, N Schoof, JJ Waggoner, RR Kempker, PA Rebolledo, JW O'Neal, C Stone, A Chahroudi, CR Morris, A Suessmith, J Sullivan, S Farmer, A Foster, JD Roback, T Ramachandra, C Washington, K Le, MC Cordero, A Esper, EJ Nehl, YF Wang, EA Tyburski, GS Martin, WA Lam	07/16/2021
Vascularized Microfluidics and Their Untapped Potential for Discovery in Diseases of the Microvasculature. Annual review of biomedical engineering	DR Myers, WA Lam	07/13/2021
Platelet heterogeneity enhances blood clot volumetric contraction: An example of asynchrono-mechanical amplification. Biomaterials	Y Sun, DR Myers, SV Nikolov, O Oshinowo, J Baek, SM Bowie, TP Lambert, E Woods, Y Sakurai, WA Lam, A Alexeev	07/01/2021
Physical forces regulating hemostasis and thrombosis: Vessels, cells, and molecules in illustrated review. Research and practice in thrombosis and haemostasis	J Lin, MG Sorrells, WA Lam, KB Neeves	07/01/2021
The RADx Tech Test Verification Core and the ACME POCT in the Evaluation of COVID-19 Testing Devices: A Model for Progress and Change. IEEE open journal of engineering in medicine and biology	E Nehl, S Heilman, D Ku, D Gottfried, S Farmer, R Mannino, E Tyburski, J Sullivan, A Suessmith, L Bassit, J Figueroa, A Wood, T Leong, A Rao, B Rogers, R Jerris, S Park, M Gonzalez, J Frediani, C Morris, J Levy, N Schoof, M Mavigner, J Roback, K Herzegh, N Saakadze, J Ingersoll, N Cheedarla, A Neish, B Hanberry, C Porter, A Esper, R Kempker, P Rebolledo, P McGuinness, F Balagadde, R Gore, A Koren, N Pollock, E Rogers, K Simin, N Hafer, MA Picard, C Ghezzi, D McManus, B Buchholz, C Rostad, V Claveria, T Ramachandra, YF Wang, C Washington, C Stone, M Griffiths, R Schinazi, A Chahroudi, M Vos, O Brand, G Martin, W Lam	04/28/2021
Future potential of Rapid Acceleration of Diagnostics (RADx Tech) in molecular diagnostics. Expert review of molecular diagnostics	SC Schachter, DR Dunlap, WA Lam, YC Manabe, GS Martin, SM McFall	03/01/2021
Point-of-Care Diagnostic Assays and Novel Preclinical Technologies for Hemostasis and Thrombosis. Seminars in thrombosis and hemostasis	C Caruso, WA Lam	03/01/2021
In vitro flow-based assay: From simple toward more sophisticated models for mimicking hemostasis and thrombosis. Journal of thrombosis and haemostasis : JTH	PH Mangin, KB Neeves, WA Lam, JMEM Cosemans, N Korin, SW Kerrigan, MA Panteleev	02/01/2021
Significant differences in single-platelet biophysics exist across species but attenuate during clot formation. Blood advances	O Oshinowo, R Copeland, Y Sakurai, ME Fay, BG Petrich, T Leong, B Brainard, WA Lam	01/26/2021
RADx Variant Task Force Program for Assessing the Impact of Variants on SARS-CoV-2 Molecular and Antigen Tests. IEEE open journal of engineering in medicine and biology	R Creager, J Blackwood, T Pribyl, L Bassit, A Rao, M Greenleaf, F Frank, W Lam, E Ortlund, R Schinazi, A Greninger, M Cirrincione, D Gort, E Kennedy, A Samuta, M Shaw, B Walsh, E Lai	01/01/2021
The RADx Tech Clinical Studies Core: A Model for Academic Based Clinical Studies. IEEE open journal of engineering in medicine and biology	L Gibson, N Fahey, N Hafer, B Buchholz, D Dunlap, R Murphy, C Achenbach, C Stone, R Cleeton, J O'Neal, J Frediani, M Vos, O Brand, R Nayee, L Wells, W Lam, G Martin, Y Manabe, M Robinson, J Broach, J Olgin, B Barton, S Lemon, A Blodgett, D McManus	01/01/2021
AnemoCheck-LRS: an optimized, color-based point-of-care test to identify severe anemia in limited-resource settings. BMC medicine	MS Perez-Plazola, EA Tyburski, LR Smart, TA Howard, A Pfeiffer, RE Ware, WA Lam, PT McGann	11/16/2020
A blueprint for academic laboratories to produce SARS-CoV-2 quantitative RT-PCR test kits. The Journal of biological chemistry	SJ Mascuch, S Fakhretaha-Aval, JC Bowman, MTH Ma, G Thomas, B Bommarius, C Ito, L Zhao, GP Newnam, KR Matange, HR Thapa, B Barlow, RK Donegan, NA Nguyen, EG Saccuzzo, CT Obianyor, SC Karunakaran, P Pollet, B Rothschild-Mancinelli, S Mestre-Fos, R Guth-Metzler, AV Bryksin, AS Petrov, M Hazell, CB Ibberson, PI Penev, RG Mannino, WA Lam, AJ Garcia, J Kubanek, V Agarwal, NV Hud, JB Glass, LD Williams, RL Lieberman	11/13/2020
Stiffness based enrichment of leukemia cells using microfluidics. APL bioengineering	M Islam, A Raj, B McFarland, HM Brink, J Ciciliano, M Fay, DR Myers, C Flowers, EK Waller, W Lam, A Alexeev, T Sulchek	09/01/2020
Decreased cell stiffness enhances leukemia development and progression. Leukemia	L Hu, F Ni, X Wang, ME Fay, KM Young, WA Lam, TA Sulchek, CK Qu	09/01/2020
A blueprint for academic labs to produce SARS-CoV-2 RT-qPCR test kits. medRxiv : the preprint server for health sciences	SJ Mascuch, S Fakhretaha-Aval, JC Bowman, MTH Ma, G Thomas, B Bommarius, C Ito, L Zhao, GP Newnam, KR Matange, HR Thapa, B Barlow, RK Donegan, NA Nguyen, EG Saccuzzo, CT Obianyor, SC Karunakaran, P Pollet, B Rothschild-Mancinelli, S Mestre-Fos, R Guth-Metzler, AV Bryksin, AS Petrov, M Hazell, CB Ibberson, PI Penev, RG Mannino, WA Lam, AJ Garcia, JM Kubanek, V Agarwal, NV Hud, JB Glass, LD Williams, RL Lieberman	09/01/2020
Hematocrit significantly confounds diffuse correlation spectroscopy measurements of blood flow. Biomedical optics express	E Sathialingam, EK Williams, SY Lee, CE McCracken, WA Lam, EM Buckley	08/01/2020
Getting a good view: in vitro imaging of platelets under flow. Platelets	O Oshinowo, T Lambert, Y Sakurai, R Copeland, CE Hansen, WA Lam, DR Myers	07/03/2020
Label-free hematology analysis using deep-ultraviolet microscopy. Proceedings of the National Academy of Sciences of the United States of America	A Ojaghi, G Carrazana, C Caruso, A Abbas, DR Myers, WA Lam, FE Robles	06/30/2020
Platelet-rich plasma as endothelial rocket fuel for engineered in vitro microvasculature. Journal of thrombosis and haemostasis : JTH	Y Qiu, WA Lam	06/01/2020
Flow-induced segregation and dynamics of red blood cells in sickle cell disease. Physical review fluids	X Zhang, C Caruso, WA Lam, MD Graham	05/01/2020
In vitro flow based systems to study platelet function and thrombus formation: Recommendations for standardization: Communication from the SSC on Biorheology of the ISTH. Journal of thrombosis and haemostasis : JTH	PH Mangin, EE Gardiner, WS Nesbitt, SW Kerrigan, N Korin, WA Lam, MA Panteleev	03/01/2020
Diabetes affects endothelial cell function and alters fibrin clot formation in a microvascular flow model: A pilot study. Diabetes & vascular disease research	L Jenny, A Melmer, M Laimer, ET Hardy, WA Lam, V Schroeder	01/01/2020
Microfluidic Approach for Highly Efficient Viral Transduction. Methods in molecular biology (Clifton, N.J.)	R Tran, WA Lam	01/01/2020
Vascularized Microfluidics and the Blood-Endothelium Interface. Micromachines	CA Hesh, Y Qiu, WA Lam	12/23/2019
Diagnosis of acute serious illness: the role of point-of-care technologies. Current opinion in biomedical engineering	GL Damhorst, EA Tyburski, O Brand, GS Martin, WA Lam	09/01/2019
Point-of-Care Technology Research Network: An evolving model for collaborative translational research in biomedical engineering. Current opinion in biomedical engineering	PF Carleton, S Schachter, TB Lash, J Chen, T Merchak, O Brand, B Buchholz, C Gaydos, W Lam, Y Manabe, G Martin, S McFall, D McManus, R Murphy, J Parrish	09/01/2019
Noninvasive optical assessment of resting-state cerebral blood flow in children with sickle cell disease. Neurophotonics	SY Lee, KR Cowdrick, B Sanders, E Sathialingam, CE McCracken, WA Lam, CH Joiner, EM Buckley	07/01/2019
The biophysics and mechanics of blood from a materials perspective. Nature reviews. Materials	Y Qiu, DR Myers, WA Lam	05/01/2019
Ptpn21 Controls Hematopoietic Stem Cell Homeostasis and Biomechanics. Cell stem cell	F Ni, WM Yu, X Wang, ME Fay, KM Young, Y Qiu, WA Lam, TA Sulchek, T Cheng, DT Scadden, CK Qu	04/04/2019
Enabling mesenchymal stromal cell immunomodulatory analysis using scalable platforms. Integrative biology : quantitative biosciences from nano to macro	EK Williams, JR García, RG Mannino, RS Schneider, WA Lam, AJ García	04/01/2019
Dynamics of deformable straight and curved prolate capsules in simple shear flow. Physical review fluids	X Zhang, WA Lam, MD Graham	04/01/2019
Feeling the Force: Measurements of Platelet Contraction and Their Diagnostic Implications. Seminars in thrombosis and hemostasis	EK Williams, O Oshinowo, A Ravindran, WA Lam, DR Myers	04/01/2019
Integrated automated particle tracking microfluidic enables high-throughput cell deformability cytometry for red cell disorders. American journal of hematology	P Guruprasad, RG Mannino, C Caruso, H Zhang, CD Josephson, JD Roback, WA Lam	02/01/2019
Smartphone app for non-invasive detection of anemia using only patient-sourced photos. Nature communications	RG Mannino, DR Myers, EA Tyburski, C Caruso, J Boudreaux, T Leong, GD Clifford, WA Lam	12/04/2018
Interdigitated microelectronic bandage augments hemostasis and clot formation at low applied voltage in vitro and in vivo. Lab on a chip	ET Hardy, YJ Wang, S Iyer, RG Mannino, Y Sakurai, TH Barker, T Chi, Y Youn, H Wang, AC Brown, WA Lam	09/26/2018
Protein Corona in Response to Flow: Effect on Protein Concentration and Structure. Biophysical journal	DT Jayaram, SM Pustulka, RG Mannino, WA Lam, CK Payne	07/17/2018
Ultraviolet Hyperspectral Interferometric Microscopy. Scientific reports	A Ojaghi, ME Fay, WA Lam, FE Robles	07/02/2018
Advances in Clinical and Basic Science of Coagulation: Illustrated abstracts of the 9th Chapel Hill Symposium on Hemostasis. Research and practice in thrombosis and haemostasis	W Bergmeier, S Antoniak, EM Conway, CV Denis, LA George, B Isermann, NS Key, S Krishnaswamy, WA Lam, D Lillicrap, J Liu, MR Looney, JA López, C Maas, F Peyvandi, W Ruf, AK Sood, HH Versteeg, AS Wolberg, PC Wong, JP Wood, H Weiler	07/01/2018
Platelet Mechanotransduction. Annual review of biomedical engineering	CE Hansen, Y Qiu, OJT McCarty, WA Lam	06/04/2018
Engineering "Endothelialized" Microfluidics for Investigating Vascular and Hematologic Processes Using Non-Traditional Fabrication Techniques. Current opinion in biomedical engineering	RG Mannino, NK Pandian, A Jain, WA Lam	03/01/2018
Thrombosis-on-a-chip: Prospective impact of microphysiological models of vascular thrombosis. Current opinion in biomedical engineering	NKR Pandian, RG Mannino, WA Lam, A Jain	03/01/2018
Microfluidic cell sorting by stiffness to examine heterogenic responses of cancer cells to chemotherapy. Cell death & disease	M Islam, R Mezencev, B McFarland, H Brink, B Campbell, B Tasadduq, EK Waller, W Lam, A Alexeev, T Sulchek	02/14/2018
A microengineered vascularized bleeding model that integrates the principal components of hemostasis. Nature communications	Y Sakurai, ET Hardy, B Ahn, R Tran, ME Fay, JC Ciciliano, RG Mannino, DR Myers, Y Qiu, MA Carden, WH Baldwin, SL Meeks, GE Gilbert, SM Jobe, WA Lam	02/06/2018
Simultaneous point-of-care detection of anemia and sickle cell disease in Tanzania: the RAPID study. Annals of hematology	LR Smart, EE Ambrose, KC Raphael, A Hokororo, E Kamugisha, EA Tyburski, WA Lam, RE Ware, PT McGann	02/01/2018
Mapping the 3D orientation of piconewton integrin traction forces. Nature methods	JM Brockman, AT Blanchard, V Pui-Yan, WD Derricotte, Y Zhang, ME Fay, WA Lam, FA Evangelista, AL Mattheyses, K Salaita	02/01/2018
Platelet integrins exhibit anisotropic mechanosensing and harness piconewton forces to mediate platelet aggregation. Proceedings of the National Academy of Sciences of the United States of America	Y Zhang, Y Qiu, AT Blanchard, Y Chang, JM Brockman, VP Ma, WA Lam, K Salaita	01/09/2018
3D in vitro microvascular model-based lymphoma model. Methods in cell biology	RG Mannino, P Pradhan, K Roy, WA Lam	01/01/2018
Microvasculature-on-a-chip for the long-term study of endothelial barrier dysfunction and microvascular obstruction in disease. Nature biomedical engineering	Y Qiu, B Ahn, Y Sakurai, CE Hansen, R Tran, PN Mimche, RG Mannino, JC Ciciliano, TJ Lamb, CH Joiner, SF Ofori-Acquah, WA Lam	01/01/2018
Variations in pediatric emergency medicine physician practices for intravenous fluid management in children with sickle cell disease and vaso-occlusive pain: A single institution experience. Pediatric blood & cancer	MA Carden, P Patil, ME Ahmad, WA Lam, CH Joiner, CR Morris	01/01/2018
MASP-1 of the complement system enhances clot formation in a microvascular whole blood flow model. PloS one	L Jenny, J Dobó, P Gál, G Pál, WA Lam, V Schroeder	01/01/2018
Extracellular fluid tonicity impacts sickle red blood cell deformability and adhesion. Blood	MA Carden, ME Fay, X Lu, RG Mannino, Y Sakurai, JC Ciciliano, CE Hansen, S Chonat, CH Joiner, DK Wood, WA Lam	12/14/2017
Enhancing size based size separation through vertical focus microfluidics using secondary flow in a ridged microchannel. Scientific reports	B Tasadduq, W Lam, A Alexeev, AF Sarioglu, T Sulchek	12/12/2017
Clinical Implications of Single-Cell Microfluidic Devices for Hematological Disorders. Analytical chemistry	CE Hansen, WA Lam	11/21/2017
Probing blood cell mechanics of hematologic processes at the single micron level. Lab on a chip	JC Ciciliano, R Abbaspour, J Woodall, C Wu, MS Bakir, WA Lam	11/07/2017
Towards remote assessment and screening of acute abdominal pain using only a smartphone with native accelerometers. Scientific reports	DR Myers, A Weiss, MR Rollins, WA Lam	10/06/2017
Microfluidic Transduction Harnesses Mass Transport Principles to Enhance Gene Transfer Efficiency. Molecular therapy : the journal of the American Society of Gene Therapy	R Tran, DR Myers, G Denning, JE Shields, AM Lytle, H Alrowais, Y Qiu, Y Sakurai, WC Li, O Brand, JM Le Doux, HT Spencer, CB Doering, WA Lam	10/04/2017
Novel in vivo and in vitro techniques to image and model the cerebral vasculature in sickle cell disease. Blood cells, molecules & diseases	EM Buckley, MO Platt, WA Lam	09/01/2017
Normal saline is associated with increased sickle red cell stiffness and prolonged transit times in a microfluidic model of the capillary system. Microcirculation (New York, N.Y. : 1994)	MA Carden, M Fay, Y Sakurai, B McFarland, S Blanche, C DiPrete, CH Joiner, T Sulchek, WA Lam	07/01/2017
Platelet-Microcapsule Hybrids Leverage Contractile Force for Targeted Delivery of Hemostatic Agents. ACS nano	CE Hansen, DR Myers, WH Baldwin, Y Sakurai, SL Meeks, LA Lyon, WA Lam	06/27/2017
Magnetic forces enable controlled drug delivery by disrupting endothelial cell-cell junctions. Nature communications	Y Qiu, S Tong, L Zhang, Y Sakurai, DR Myers, L Hong, WA Lam, G Bao	06/08/2017
Microfluidic Sorting of Cells by Viability Based on Differences in Cell Stiffness. Scientific reports	M Islam, H Brink, S Blanche, C DiPrete, T Bongiorno, N Stone, A Liu, A Philip, G Wang, W Lam, A Alexeev, EK Waller, T Sulchek	05/17/2017
Single-platelet nanomechanics measured by high-throughput cytometry. Nature materials	DR Myers, Y Qiu, ME Fay, M Tennenbaum, D Chester, J Cuadrado, Y Sakurai, J Baek, R Tran, JC Ciciliano, B Ahn, RG Mannino, ST Bunting, C Bennett, M Briones, A Fernandez-Nieves, ML Smith, AC Brown, T Sulchek, WA Lam	02/01/2017
3D microvascular model recapitulates the diffuse large B-cell lymphoma tumor microenvironment in vitro. Lab on a chip	RG Mannino, AN Santiago-Miranda, P Pradhan, Y Qiu, JC Mejias, SS Neelapu, K Roy, WA Lam	01/31/2017
Assessment of a Smartphone Otoscope Device for the Diagnosis and Management of Otitis Media. Clinical pediatrics	KM Rappaport, CC McCracken, J Beniflah, WK Little, DA Fletcher, WA Lam, AL Shane	08/01/2016
Cellular softening mediates leukocyte demargination and trafficking, thereby increasing clinical blood counts. Proceedings of the National Academy of Sciences of the United States of America	ME Fay, DR Myers, A Kumar, CT Turbyfield, R Byler, K Crawford, RG Mannino, A Laohapant, EA Tyburski, Y Sakurai, MJ Rosenbluth, NA Switz, TA Sulchek, MD Graham, WA Lam	02/23/2016
An accurate and inexpensive color-based assay for detecting severe anemia in a limited-resource setting. American journal of hematology	PT McGann, EA Tyburski, V de Oliveira, B Santos, RE Ware, WA Lam	12/01/2015
Platelets and physics: How platelets "feel" and respond to their mechanical microenvironment. Blood reviews	Y Qiu, J Ciciliano, DR Myers, R Tran, WA Lam	11/01/2015
Factor XIIIa-dependent retention of red blood cells in clots is mediated by fibrin α-chain crosslinking. Blood	JR Byrnes, C Duval, Y Wang, CE Hansen, B Ahn, MJ Mooberry, MA Clark, JM Johnsen, ST Lord, WA Lam, JC Meijers, H Ni, RA Ariëns, AS Wolberg	10/15/2015
Resolving the multifaceted mechanisms of the ferric chloride thrombosis model using an interdisciplinary microfluidic approach. Blood	JC Ciciliano, Y Sakurai, DR Myers, ME Fay, B Hechler, S Meeks, R Li, JB Dixon, LA Lyon, C Gachet, WA Lam	08/06/2015
Platelet geometry sensing spatially regulates α-granule secretion to enable matrix self-deposition. Blood	Y Sakurai, JL Fitch-Tewfik, Y Qiu, B Ahn, DR Myers, R Tran, ME Fay, L Ding, PW Spearman, AD Michelson, R Flaumenhaft, WA Lam	07/23/2015
"Do-it-yourself in vitro vasculature that recapitulates in vivo geometries for investigating endothelial-blood cell interactions". Scientific reports	RG Mannino, DR Myers, B Ahn, Y Wang, null Margo Rollins, H Gole, AS Lin, RE Guldberg, DP Giddens, LH Timmins, WA Lam	07/23/2015
Microfluidic cellular enrichment and separation through differences in viscoelastic deformation. Lab on a chip	G Wang, K Crawford, C Turbyfield, W Lam, A Alexeev, T Sulchek	01/21/2015
Platelet mechanosensing of collagen matrices. PloS one	MF Kee, DR Myers, Y Sakurai, WA Lam, Y Qiu	01/01/2015
Ultrasoft microgels displaying emergent platelet-like behaviours. Nature materials	AC Brown, SE Stabenfeldt, B Ahn, RT Hannan, KS Dhada, ES Herman, V Stefanelli, N Guzzetta, A Alexeev, WA Lam, LA Lyon, TH Barker	12/01/2014
Platelet mechanosensing of substrate stiffness during clot formation mediates adhesion, spreading, and activation. Proceedings of the National Academy of Sciences of the United States of America	Y Qiu, AC Brown, DR Myers, Y Sakurai, RG Mannino, R Tran, B Ahn, ET Hardy, MF Kee, S Kumar, G Bao, TH Barker, WA Lam	10/07/2014
Disposable platform provides visual and color-based point-of-care anemia self-testing. The Journal of clinical investigation	EA Tyburski, SE Gillespie, WA Stoy, RG Mannino, AJ Weiss, AF Siu, RH Bulloch, K Thota, A Cardenas, W Session, HJ Khoury, S O'Connor, ST Bunting, J Boudreaux, CR Forest, M Gaddh, T Leong, LA Lyon, WA Lam	10/01/2014
Actin cytoskeletal disruption following cryopreservation alters the biodistribution of human mesenchymal stromal cells in vivo. Stem cell reports	R Chinnadurai, MA Garcia, Y Sakurai, WA Lam, AD Kirk, J Galipeau, IB Copland	07/08/2014
Simplified prototyping of perfusable polystyrene microfluidics. Biomicrofluidics	R Tran, B Ahn, DR Myers, Y Qiu, Y Sakurai, R Moot, E Mihevc, H Trent Spencer, C Doering, W A Lam	07/01/2014
The platelet and the biophysical microenvironment: lessons from cellular mechanics. Thrombosis research	JC Ciciliano, R Tran, Y Sakurai, WA Lam	04/01/2014
Using microfluidics to investigate hematopoietic stem cell and microniche interactions at the single cell level. Methods in molecular biology (Clifton, N.J.)	B Ahn, Z Wang, DR Archer, WA Lam	01/01/2014
Mitochondrially mediated integrin αIIbβ3 protein inactivation limits thrombus growth. The Journal of biological chemistry	F Liu, G Gamez, DR Myers, W Clemmons, WA Lam, SM Jobe	10/18/2013
Anionic lipids are required for vesicular stomatitis virus G protein-mediated single particle fusion with supported lipid bilayers. The Journal of biological chemistry	PM Matos, M Marin, B Ahn, W Lam, NC Santos, GB Melikyan	05/03/2013
Biomechanics of haemostasis and thrombosis in health and disease: from the macro- to molecular scale. Journal of cellular and molecular medicine	R Tran, DR Myers, J Ciciliano, EL Trybus Hardy, Y Sakurai, B Ahn, Y Qiu, RG Mannino, ME Fay, WA Lam	05/01/2013
Endothelialized microfluidics for studying microvascular interactions in hematologic diseases. Journal of visualized experiments : JoVE	DR Myers, Y Sakurai, R Tran, B Ahn, ET Hardy, R Mannino, A Kita, M Tsai, WA Lam	06/22/2012
Microenvironmental geometry guides platelet adhesion and spreading: a quantitative analysis at the single cell level. PloS one	A Kita, Y Sakurai, DR Myers, R Rounsevell, JN Huang, TJ Seok, K Yu, MC Wu, DA Fletcher, WA Lam	01/01/2011