Karen P. Mann, MD, PhD


Titles and Roles

Professor, Department of Pathology and Laboratory Medicine
Emory University School of Medicine
Chief Clinical Pathology
Grady Health System
Medical Director Clinical Laboratories
Grady Health System
Director, Molecular Genetic Pathology Fellowship Program
Emory University Hospital
Multiple Myeloma
Research Program
Discovery and Developmental Therapeutics


As Director of Molecular Hematopathology, Dr. Mann has a leading role in supervising the development and evaluation of new molecular hematopathology tests in order to maintain a state-of-the-art diagnostic hematopathology laboratory. Her clinical focus is in the area of neoplastic and non-neoplastic hematopathology of adults and children with an emphasis on a multifaceted approach including morphology, immunohistochemistry, flow cytometric immunophenotyping, fluorescence in situ hybridization, cytogenetics, and molecular testing. This approach is used to diagnosis the full range of hematopoietic malignancies and to evaluate for residual or recurrent disease following treatment.

Dr. Mann is board certified in anatomic pathology, hematopathology and molecular genetic pathology.


Dr. Mann earned her MD and PhD degrees from Tufts University School of Medicine and Sackler School of Biomedical Sciences.


Dr. Mann's research interest focuses on the development of new molecular diagnostic tests and flow cytometric targets which can aid in the diagnosis, subclassification, determination of prognosis, and treatment monitoring in patients with hematopoietic neoplasms. In addition, she is interested in evaluation of the usefulness of newly identified mutations both as diagnostic targets as well as possible targets of directed therapies. She is also interested in the monitoring and significance of minimal residual disease in different hematopoietic disorders.


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