Andrew H. Miller, MD

Specialty

Dr. Miller co-leads the Cancer Prevention and Control program which coordinates and promotes all of the cancer prevention and control-related research activities at Winship.

Titles and Roles

William P. Timmie Professor of Psychiatry and Behavioral Science
Emory University School of Medicine
Co-Leader, Cancer Prevention and Control Research Program
Winship Cancer Institute of Emory University
Program Director, Emory Mind Body Program
Emory University School of Medicine
Research Program
Cancer Prevention and Control

Biography

Andrew H. Miller, MD, is William P. Timmie Professor of Psychiatry and Behavioral Sciences at the Emory University School of Medicine. Dr. Miller's work focuses on the impact of the activated innate immune system on behavior and health. He is also interested in the role of glucocorticoid hormones in the regulation of inflammatory responses.

Aside from his research endeavors, Dr. Miller is a Board Certified Psychiatrist and past examiner for the American Board of Psychiatry and Neurology.

Education

Dr. Miller attended medical school at the Medical College of Georgia and did a residency in psychiatry at the Albert Einstein College of Medicine. As a junior faculty member, Dr. Miller trained with Dr. Marvin Stein at Mount Sinai School of Medicine and Dr. Bruce McEwen at Rockefeller University.

Awards

Dr. Miller's research awards include the Curt Richter Award from the International Society of Psychoneuroendocrinology and the Norman Cousins Award from the Psychoneuroimmunology Research Society.

Research

Dr. Miller's research focuses on the mechanisms by which cytokines cause depression in humans and non-human primates using chronic administration of the innate immune cytokine, interferon-alpha, as a model of chronic immune stimulation. Dr. Miller's work has shown that during chronic interferon-alpha treatment, cytokines access the brain and interact with the metabolism of relevant neurotransmitters including serotonin and dopamine. He has also shown that cytokines alter neurocircuits in the brain relevant to motivation and reward as well as anxiety and alarm. In addition, he has studied the impact of cytokines on neuroendocrine regulation as well as sleep including the study of specific signal transduction pathways that may be involved such as NF-kB and p38 mitogen activated protein kinase. Finally, Dr. Miller and his group are currently conducting clinical trials examining the efficacy of cytokine antagonists in patients with treatment resistant depression.

Publications

Dr. Miller has produced over 200 scholarly publications and edited a book entitled, Depressive Disorders and Immunity.

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