Shoichiro Ono
PhD
Dr. Ono's primary research interest is in the areas of cytoskeleton cell biology and alternative pre-mRNA splicing.
Titles and Roles
- Associate Professor, Department of Pathology and Laboratory Medicine
- Emory University School of Medicine
- Associate Professor, Department of Cell Biology
- Emory University School of Medicine
- Research Program
- Cell and Molecular Biology
Biography
Shoichiro Ono, PhD, holds joint appointments as Associate Professor in the Department of Pathology and Laboratory Medicine and Department of Cell Biology at Emory University School of Medicine. Dr. Ono serves on the Executive Committee of the Biochemistry, Cell and Developmental Biology Graduate Program at the Emory Laney Graduate School's Division of Biological and Biomedical Sciences.
Dr. Ono is a member of the Cell and Molecular Biology Research Program at Winship Cancer Institute of Emory University.
Education
Dr. Ono obtained his PhD and his MSc from Chiba University in Chiba, Japan.
Research
Dr. Ono's research interests are in the following areas:
- Cytoskeleton-Cell Biology - His lab is interested in the mechanisms of the regulation of actin cytoskeletal dynamics. Actin filaments are reorganized during development, cell migration, and cell division. Proper regulation of the actin reorganization is required for normal cellular activities, while its misregulation often causes diseases. They have been studying functions of actin-binding proteins using biochemical, cell biological, and genetic techniques.
- Alternative pre-mRNA splicing - A number of genes produce multiple transcripts by alternative splicing. Misregulation of this mechanism is involved in the pathogenesis of myotonic dystrophy. Dr. Ono's lab has identified a muscle-specific regulator of pre-mRNA splicing in the nematode C. elegans and have been studying how this splicing factor functions. This splicing factor is conserved in humans, and they hope to gain insights into the mechanism of tissue-specific pre-mRNA splicing.
Publications
Dr. Ono has extensive publications in major peer-reviewed journals. He also serves on the editorial boards of Journal of Biological Chemistry, Cytoskeleton, Cell Health and Cytoskeleton, Advanced Studies in Biology, BioMed Research International: Cell Biology Section, and International Journal of Cell Biology.
Publications Publication Date