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Himalee Sabnis, MD, MSc

Himalee S. Sabnis, MD, MSc

Biography

Board certified in pediatric hematology/oncology, Himalee S. Sabnis, MD, MSc, practices at Egleston Children's Hospital in Atlanta, Georgia. Dr. Sabnis is a member of the Discovery and Developmental Therapeutics Research Program at Winship Cancer Institute of Emory University in Atlanta, Georgia.

Education

Dr. Sabnis received her medical degree from Seth Gordhandas Sunderdas Medical College at the University of Mumbai in India. She completed a residency in pediatrics at Children's Hospital of Michigan in Detroit, MI. She also completed a fellowship in pediatric hematology and oncology at Emory University in Atlanta.

Titles & Roles

  • Associate Professor, Department of Pediatrics
    Emory University School of Medicine

Professional Memberships

Dr. Sabnis holds professional memberships with the American Society of Hematology, American Society of Pediatric Hematology and Oncology, American Society of Clinical Oncology and Children's Oncology Group. 

Research

Dr. Sabnis' research areas of interest include biology of acute myeloid leukemia (AML), and signaling pathways in leukemic cells and new therapeutic agents in AML.

  • Samotolisib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With TSC or PI3K/MTOR Mutations (A Pediatric MATCH Treatment Trial)

    • Phase
      II
    • Conditions
      Advanced Malignant Solid Neoplasm, Ann Arbor Stage III Non-Hodgkin Lymphoma, Ann Arbor Stage IV Non-Hodgkin Lymphoma, Malignant Glioma, Recurrent Ependymoma, Recurrent Ewing Sarcoma, Recurrent Glioma, Recurrent Hepatoblastoma, Recurrent Langerhans Cell Histiocytosis, Recurrent Malignant Germ Cell Tumor, Recurrent Malignant Solid Neoplasm, Recurrent Medulloblastoma, Recurrent Neuroblastoma, Recurrent Non-Hodgkin Lymphoma, Recurrent Osteosarcoma, Recurrent Peripheral Primitive Neuroectodermal Tumor, Recurrent Primary Central Nervous System Neoplasm, Recurrent Rhabdomyosarcoma, Recurrent Soft Tissue Sarcoma, Refractory Langerhans Cell Histiocytosis, Refractory Malignant Germ Cell Tumor, Refractory Malignant Solid Neoplasm, Refractory Neuroblastoma, Refractory Non-Hodgkin Lymphoma, Refractory Primary Central Nervous System Neoplasm, Rhabdoid Tumor, Stage III Osteosarcoma AJCC v7, Stage III Soft Tissue Sarcoma AJCC v7, Stage IV Osteosarcoma AJCC v7, Stage IV Soft Tissue Sarcoma AJCC v7, Stage IVA Osteosarcoma AJCC v7, Stage IVB Osteosarcoma AJCC v7, Wilms Tumor
    • Location
      Winship Cancer Institute

Publications

Title/Journal Authors Publication Date

Single-cell analysis reveals altered tumor microenvironments of relapse- and remission-associated pediatric acute myeloid leukemia.

Nature communications

 H Mumme, BE Thomas, SS Bhasin, U Krishnan, B Dwivedi, P Perumalla, D Sarkar, GB Ulukaya, HS Sabnis, SI Park, D DeRyckere, SS Raikar, M Pauly, RJ Summers, SM Castellino, DS Wechsler, CC Porter, DK Graham, M Bhasin 10/05/2023

Inflammation or Infiltration? Infiltrative Cardiovascular Chloroma Presenting With Syncope and Heart Block.

Circulation. Cardiovascular imaging

 HC Wilson, S Hashemi, HS Sabnis, AL Hong, EC Michelfelder 01/01/2023

Association of race/ethnicity with innate immune tumor microenvironment of children with B-acute lymphoblastic leukemia.

Journal for immunotherapy of cancer

 JR Gilbert, HS Sabnis, R Radzievski, DB Doxie, D DeRyckere, SM Castellino, K Dhodapkar 06/01/2022

Multicenter Analysis of Genomically Targeted Single Patient Use Requests for Pediatric Neoplasms.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

 HS Sabnis, DS Shulman, B Mizukawa, N Bouvier, A Zehir, J Fangusaro, VA Fabrizio, C Whitlow, M Winchester, L Agresta, B Turpin, DS Wechsler, SG DuBois, J Glade-Bender, SM Castellino, N Shukla 12/01/2021

Immune responses and therapeutic challenges in paediatric patients with new-onset acute myeloid leukaemia and concomitant COVID-19.

British journal of haematology

 PA Patel, SA Lapp, G Grubbs, VV Edara, CA Rostad, CL Stokes, MG Pauly, EJ Anderson, A Piantadosi, MS Suthar, S Khurana, HS Sabnis 08/01/2021

Pimozide and Imipramine Blue Exploit Mitochondrial Vulnerabilities and Reactive Oxygen Species to Cooperatively Target High Risk Acute Myeloid Leukemia.

Antioxidants (Basel, Switzerland)

 Z Wang, T Mi, HL Bradley, J Metts, H Sabnis, W Zhu, J Arbiser, KD Bunting 06/15/2021

Patterns of surveillance for late effects of BCR-ABL tyrosine kinase inhibitors in survivors of pediatric Philadelphia chromosome positive leukemias.

BMC cancer

 SM Smith, HS Sabnis, RW Lewis, KE Effinger, J Bergsagel, B Patterson, A Mertens, KM Sakamoto, L Schapira, SM Castellino 04/29/2021

A strategy to reduce cumulative anthracycline exposure in low-risk pediatric acute myeloid leukemia while maintaining favorable outcomes.

Leukemia research

 HS Sabnis, KA Minson, C Monroe, K Allen, JL Metts, TM Cooper, WG Woods, SM Castellino, FG Keller 09/01/2020

Severe COVID-19 disease in two pediatric oncology patients.

Pediatric blood & cancer

 CL Stokes, PA Patel, HS Sabnis, SG Mitchell, IB Yildirim, MG Pauly 09/01/2020

Very late recurrence of B-cell acute lymphoblastic leukemia masquerading as a pituitary tumor.

Pediatric hematology and oncology

 DM Fridlyand, FG Keller, HS Sabnis, BC Patterson, JA Gadde, JH Peragallo, V Biousse, DS Wechsler 08/01/2020

Growth disturbances in children and adolescents receiving long-term tyrosine kinase inhibitor therapy for Chronic Myeloid Leukaemia or Philadelphia Chromosome-positive Acute Lymphoblastic Leukaemia.

British journal of haematology

 HS Sabnis, C Keenum, RW Lewis, B Patterson, J Bergsagel, KE Effinger, E Silverman, AC Mertens, SM Castellino 05/01/2019

Acute Myeloid Leukemia in an Infant with t(8;19)(p11.2;q13) Translocation: Case Report and a Review of the Literature.

Case reports in hematology

 AC Eason, ST Bunting, JF Peterson, D Saxe, HS Sabnis 01/01/2019

Targeting MYC Dependence by Metabolic Inhibitors in Cancer.

Genes

 HS Sabnis, RR Somasagara, KD Bunting 03/31/2017

Synergistic cell death in FLT3-ITD positive acute myeloid leukemia by combined treatment with metformin and 6-benzylthioinosine.

Leukemia research

 HS Sabnis, HL Bradley, S Tripathi, WM Yu, W Tse, CK Qu, KD Bunting 11/01/2016

Early T-Cell Precursor Acute Lymphoblastic Leukemia in an Infant With an NRAS Q61R Mutation and Clinical Features of Juvenile Myelomonocytic Leukemia.

Pediatric blood & cancer

 SS Raikar, JD Scarborough, H Sabnis, J Bergsagel, D Wu, TM Cooper, FG Keller, BL Wood, ST Bunting 09/01/2016