Malathy Shanmugam
PhD, MS
Dr. Shanmugam's research focus includes investigating the mechanistic basis for how cancer metabolism promotes evasion of apoptosis and therapy resistance in multiple myeloma and how metabolic states promote proliferative versus invasive biology.
Titles and Roles
- Associate Professor, Department of Hematology and Medical Oncology
- Emory University School of Medicine
- Research Program
- Cell and Molecular Biology
Biography
Malathy Shanmugam, PhD, MS, is Associate Professor in the Department of Hematology and Medical Oncology at Emory School of Medicine. Dr. Shanmugam is a member of the Cell and Molecular Biology Research Program at Winship Cancer Institute.
Education
Dr. Shanmugam attended Madurai Kamaraj University in T. Nadu, India where she earned a MS in Biotechnology. She received her PhD in Tumor Cell Biology from Northwestern University Medical School in Chicago, Illinois. She completed her fellowship training at Northwestern University Medical School and at Loyola University of Chicago Medical Center.
Research
The long-term objectives of Dr. Shanmugam's research are to 1) investigate the molecular and cellular basis and implications of enhanced glucose and glutamine utilization in multiple myeloma; 2) elucidate the molecular/cellular mechanisms contributing to apoptosis sensitivity following inhibition of glucose/glutamine metabolism; 3) investigate the effects of altered metabolism on sensitivity and resistance to standard myeloma chemo/immunotherapy and lastly; 4) explore how metabolic heterogeneity promotes lung cancer cell invasion.
Her lab's translational goal is to investigate cancer metabolism as a conduit to understanding cancer biology. They seek to identify targetable metabolic vulnerabilities to overcome therapy resistance and target cancer.
Publications
Publications Publication Date
Awards
Dr. Shanmugam has earned the following awards and honors:
- MilliPub Club, Emory University School of Medicine, 2015
- Best Abstract Platform Presentation, "Nucleosides, Nucleotides, & Oligonucleotides", Gordon Research Conference, Rhode Island, July 2009
- Postdoctoral NRSA Fellowship: NIH Training Grant-T32 A107508, Experimental Immunology, 2001-2004
- Gramm Travel Fellowship Award, Lurie Cancer Center, Northwestern University Medical School, 1997
- Northwestern University Representative, Dept. of Defense Breast Cancer Research Meeting, Washington, DC, 1997