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Cancer Genetics and Epigenetics

The goal of the Cancer Genetics and Epigenetics (CGE) Program is to better understand the fundamental mechanisms underlying genetic and epigenetic instability and its contribution to the initiation and progression of human tumors.  In pursuit of this goal, the CGE Program organizes its research efforts into three areas of focus: 1) DNA damage and repair and genome instability; 2) epigenetics and gene regulation; and 3) cancer genetics/genomics.

Discovery efforts have led to the identification of key genes whose mutation or altered expression contributes to cancer initiation and progression.  Basic discoveries in the area of cancer epigenetics have prompted early small molecule screening efforts to identify novel targeted agents.

View recent publications by CGE Program members

Program leaders:
Paula Vertino, PhD

Jin-Tang Dong, PhD

To find out more about this research program, email Stacy Holloway at

Learn about Emory University's Cancer Biology Graduate Program by visiting our website.