Cancer Genetics and Epigenetics

The goal of the Cancer Genetics and Epigenetics research program at Winship Cancer Institute of Emory University is to better understand the fundamental mechanisms underlying genetic and epigenetic instability and its contribution to the initiation and progression of human tumors and to exploit these mechanisms to reduce cancer mortality.

A key long-term goal of the Cancer Genetics and Epigenetics research program is to interface with other components of the Winship Cancer Institute and its membership to define the genetic and epigenetic determinants of therapeutic response and clinical outcome, and to identify novel targets for therapeutic intervention.

The Cancer Genetics and Epigenetics research program accomplishes its goal through studies revolving around three inter-related and complementary thematic areas:

  • DNA damage and repair and genome instability;
  • epigenetics and gene regulation;
  • cancer genetics/genomics.

Discovery efforts have led to the identification of key genes whose mutation or altered expression contributes to cancer initiation and progression. Basic discoveries in the area of cancer epigenetics have prompted early small molecule screening efforts to identify novel targeted agents.

Led by Lawrence Boise, PhD, and Wei Zhou, PhD, the program comprises twenty-eight core members from thirteen academic departments and three schools at Emory University, including Emory College, the School of Medicine, and the School of Public Health, with coalition investigators from the Georgia Institute of Technology.

Cancer Genetics and Epigenetics program members continuously publish high-quality research in premier scientific journals.

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PublicationsPublication Date

To learn more about the Cancer Genetics and Epigenetics research program at Winship Cancer Institute, please contact Lawrence Boise, PhD at (404) 778-4724.

Visit the Emory University's Cancer Biology Graduate Program website to learn about outstanding training opportunities in every aspect of cancer research, from basic to translational.

Photo of  Lawrence Boise, PhD
Lawrence Boise, PhD

Lawrence Boise, PhD

Professor and Vice Chair for Basic Research, Department of Hematology and Medical Oncology
Emory University School of Medicine

Dr. Boise is a renowned researcher in the area of multiple myeloma.

Photo of  Wei Zhou, PhD
Wei Zhou, PhD

Wei Zhou, PhD

Professor, Department of Hematology and Medical Oncology
Emory University School of Medicine

Dr. Zhou's research focuses on molecular genetics of human cancer.

Cascade Link
Rebecca S. Arnold, PhD, MS
Assistant Professor, Department of Urology, Emory University School of Medicine
    Cecelia A. Bellcross, PhD, MS, CGC
    Associate Professor, Department of Human Genetics, Emory University School of Medicine
      Jeremy M. Boss, PhD
      Professor and Chair, Department of Microbiology and Immunology, Emory University School of Medicine
        Karen Conneely, PhD
        Associate Professor, Department of Human Genetics, Emory University School of Medicine
          Lee Cooper, PhD, MS
          Assistant Professor, Department of Biomedical Informatics, Emory University School of Medicine
            Anita H. Corbett, PhD
            Professor of Biochemistry, Department of Biology, Emory College of Arts and Sciences
              Victor Corces, PhD
              Arts & Sciences Distinguished Professor, Department of Biology, Emory University
                Gray Crouse, PhD
                Professor, Department of Biology, Emory University
                  Paul W. Doetsch, PhD
                  Professor, Radiation Oncology, Biochemistry, Hematology and Medical Oncology, Emory University School of Medicine
                    Jin-Tang Dong, PhD
                    Professor, Department of Hematology and Medical Oncology, Emory University School of Medicine
                      William S. Dynan, PhD
                      Professor, Department of Radiation Oncology, Emory University School of Medicine
                        Homa Ghalei, PhD
                        Assistant Professor, Department of Biochemistry, Emory University School of Medicine
                          Peng Jin, PhD
                          Professor, Department of Human Genetics, Emory University School of Medicine
                            David J. Katz, PhD
                            Associate Professor, Department of Cell Biology, Emory University School of Medicine
                              Yonggang Ke, PhD
                              Assistant Professor, Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University
                                William G. Kelly, PhD
                                Professor, Department of Biology, Emory University
                                  Haydn T. Kissick, PhD
                                  Senior Research Associate, Division of Translational Research, Department of Urology, Emory University School of Medicine
                                    Alyssa M. Krasinskas, MD
                                    Professor, Department of Pathology & Laboratory Medicine, Emory University School of Medicine
                                      Uma Krishnamurti, MD, PhD
                                      Associate Professor, Department of Pathology & Laboratory Medicine, Emory University School of Medicine
                                        Xiaoxian (Bill) Li, MD, PhD
                                        Associate Professor, Department of Pathology & Laboratory Medicine, Emory University School of Medicine
                                          Kirill S. Lobachev, PhD, MS
                                          Associate Professor, School of Biology, Georgia Institute of Technology
                                            Zixu Mao, MD, PhD
                                            Professor, Department of Pharmacology and Chemical Biology, Emory University School of Medicine
                                              Morgan L. McLemore, MD
                                              Assistant Professor, Department of Hematology and Medical Oncology, Emory University School of Medicine
                                                Carlos S. Moreno, PhD
                                                Associate Professor, Department of Pathology and Laboratory Medicine, Emory University School of Medicine
                                                  Ilya Nemenman, PhD, MS
                                                  Associate Professor, Department of Biology, Emory University
                                                    Mihir R. Patel, MD
                                                    Assistant Professor, Department of Otolaryngology, Emory University School of Medicine
                                                      John A. Petros, MD
                                                      Professor and Associate Chair of Research, Department of Urology, Emory University School of Medicine
                                                        Brian P. Pollack, MD, PhD
                                                        Assistant Professor, Departments of Dermatology and Pathology, Emory University School of Medicine
                                                          Christopher C. Porter, MD
                                                          Associate Professor, Department of Pediatrics, Emory University School of Medicine
                                                            Maureen A. Powers, PhD
                                                            Associate Professor, Department of Cell Biology, Emory University School of Medicine
                                                              Zhaohui "Steve" Qin, PhD, MS
                                                              Associate Professor, Department of Biostatistics and Bioinformatics, Rollins School of Public Health, Emory University
                                                                Timothy D. Read, PhD
                                                                Professor, Division of Infectious Diseases, Department of Medicine, Emory University School of Medicine
                                                                  Suma Shankar, MD, PhD
                                                                  Adjunct Assistant Professor, Department of Ophthalmology, Emory University School of Medicine
                                                                    Alicia K. Smith, PhD
                                                                    Associate Professor and Vice Chair of Research, Department of Gynecology and Obstetrics, Emory University School of Medicine
                                                                      Samuel Speck, PhD
                                                                      Professor, Department of Microbiology and Immunology, Emory University School of Medicine
                                                                        Paula M. Vertino, PhD
                                                                        Professor Emeritus, Department of Radiation Oncology, Emory University School of Medicine
                                                                          Ya Wang, PhD
                                                                          Director, Division of Experimental Radiation Oncology, Dept. of Radiation Oncology, Emory University School of Medicine
                                                                            Erica Werner, PhD
                                                                            Assistant Professor, Department of Radiation Oncology, Emory University School of Medicine
                                                                              William R. Wilcox, MD, PhD
                                                                              Professor, Department of Human Genetics, Emory University School of Medicine
                                                                                Keith D. Wilkinson, PhD
                                                                                Professor and Vice-Chair, Department of Biochemistry, Emory University School of Medicine
                                                                                  Hao Wu, PhD, MHS, MS
                                                                                  Assistant Professor, Department of Biostatistics and Bioinformatics, Emory University School of Medicine
                                                                                    Bing Yao, PhD
                                                                                    Assistant Professor, Department of Human Genetics, Emory University School of Medicine
                                                                                      David Yu, MD, PhD
                                                                                      Jerome Landry MD Chair of Cancer Biology and Associate Professor, Department of Radiation Oncology, Emory University School of Medicine
                                                                                        Linsheng Zhang, MD, PhD
                                                                                        Assistant Professor, Department of Pathology & Laboratory Medicine, Emory University School of Medicine
                                                                                          Wei Zhou, PhD
                                                                                          Professor, Department of Hematology and Medical Oncology, Emory University School of Medicine
                                                                                            Michael E. Zwick, PhD
                                                                                            Director, Emory Integrated Genomics Core, Emory University School of Medicine
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