Cancer Genetics and Epigenetics

The goal of the Cancer Genetics and Epigenetics research program at Winship Cancer Institute of Emory University is to better understand the fundamental mechanisms underlying genetic and epigenetic instability and its contribution to the initiation and progression of human tumors and to exploit these mechanisms to reduce cancer mortality.

A key long-term goal of the Cancer Genetics and Epigenetics research program is to interface with other components of the Winship Cancer Institute and its membership to define the genetic and epigenetic determinants of therapeutic response and clinical outcome, and to identify novel targets for therapeutic intervention.

The Cancer Genetics and Epigenetics research program accomplishes its goal through studies revolving around three inter-related and complementary thematic areas:

  • DNA damage and repair and genome instability;
  • epigenetics and gene regulation;
  • cancer genetics/genomics.

Discovery efforts have led to the identification of key genes whose mutation or altered expression contributes to cancer initiation and progression. Basic discoveries in the area of cancer epigenetics have prompted early small molecule screening efforts to identify novel targeted agents.

Led by Lawrence Boise, PhD, and Wei Zhou, PhD, the program comprises twenty-eight core members from thirteen academic departments and three schools at Emory University, including Emory College, the School of Medicine, and the School of Public Health, with coalition investigators from the Georgia Institute of Technology.

Cancer Genetics and Epigenetics program members continuously publish high-quality research in premier scientific journals.

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PublicationsPublication Date

To learn more about the Cancer Genetics and Epigenetics research program at Winship Cancer Institute, please contact Lawrence Boise, PhD at (404) 778-4724.

Visit the Emory University's Cancer Biology Graduate Program website to learn about outstanding training opportunities in every aspect of cancer research, from basic to translational.

Photo of  Lawrence Boise, PhD
Lawrence Boise, PhD

Lawrence Boise, PhD

Professor and Vice Chair for Basic Research, Department of Hematology and Medical Oncology
Emory University School of Medicine

Dr. Boise is a renowned researcher in the area of multiple myeloma.

Photo of  Wei Zhou, PhD
Wei Zhou, PhD

Wei Zhou, PhD

Professor, Department of Hematology and Medical Oncology
Emory University School of Medicine

Dr. Zhou's research focuses on molecular genetics of human cancer.

Cascade Link
Rebecca S. Arnold, PhD, MS
Assistant Professor, Department of Urology, Emory University School of Medicine
    Cecelia A. Bellcross, PhD, MS, CGC
    Associate Professor, Department of Human Genetics, Emory University School of Medicine
      Jeremy M. Boss, PhD
      Professor and Chair, Department of Microbiology and Immunology, Emory University School of Medicine
        Karen Conneely, PhD
        Associate Professor, Department of Human Genetics, Emory University School of Medicine
          Lee Cooper, PhD, MS
          Assistant Professor, Department of Biomedical Informatics, Emory University School of Medicine
            Anita H. Corbett, PhD
            Professor of Biochemistry, Department of Biology, Emory College of Arts and Sciences
              Gray Crouse, PhD
              Professor, Department of Biology, Emory University
                Paul W. Doetsch, PhD
                Professor, Radiation Oncology, Biochemistry, Hematology and Medical Oncology, Emory University School of Medicine
                  Jin-Tang Dong, PhD
                  Professor, Department of Hematology and Medical Oncology, Emory University School of Medicine
                    William S. Dynan, PhD
                    Professor, Department of Radiation Oncology, Emory University School of Medicine
                      Peng Jin, PhD
                      Professor, Department of Human Genetics, Emory University School of Medicine
                        David J. Katz, PhD
                        Associate Professor, Department of Cell Biology, Emory University School of Medicine
                          Yonggang Ke, PhD
                          Assistant Professor, Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University
                            William G. Kelly, PhD
                            Professor, Department of Biology, Emory University
                              Haydn T. Kissick, PhD
                              Senior Research Associate, Division of Translational Research, Department of Urology, Emory University School of Medicine
                                Alyssa M. Krasinskas, MD
                                Professor, Department of Pathology & Laboratory Medicine, Emory University School of Medicine
                                  Uma Krishnamurti, MD, PhD
                                  Associate Professor, Department of Pathology & Laboratory Medicine, Emory University School of Medicine
                                    Xiaoxian (Bill) Li, MD, PhD
                                    Associate Professor, Department of Pathology & Laboratory Medicine, Emory University School of Medicine
                                      Kirill S. Lobachev, PhD, MS
                                      Associate Professor, School of Biology, Georgia Institute of Technology
                                        Zixu Mao, MD, PhD
                                        Professor, Department of Pharmacology, Emory University School of Medicine
                                          Morgan L. McLemore, MD
                                          Assistant Professor, Department of Hematology and Medical Oncology, Emory University School of Medicine
                                            Carlos S. Moreno, PhD
                                            Associate Professor, Department of Pathology and Laboratory Medicine, Emory University School of Medicine
                                              Ilya Nemenman, PhD, MS
                                              Associate Professor, Department of Biology, Emory University
                                                Mihir R. Patel, MD
                                                Assistant Professor, Department of Otolaryngology, Emory University School of Medicine
                                                  John A. Petros, MD
                                                  Professor and Associate Chair of Research, Department of Urology, Emory University School of Medicine
                                                    Brian P. Pollack, MD, PhD
                                                    Assistant Professor, Departments of Dermatology and Pathology, Emory University School of Medicine
                                                      Christopher C. Porter, MD
                                                      Associate Professor, Department of Pediatrics, Emory University School of Medicine
                                                        Maureen A. Powers, PhD
                                                        Associate Professor, Department of Cell Biology, Emory University School of Medicine
                                                          Zhaohui "Steve" Qin, PhD, MS
                                                          Associate Professor, Department of Biostatistics and Bioinformatics, Rollins School of Public Health, Emory University
                                                            Timothy D. Read, PhD
                                                            Professor, Division of Infectious Diseases, Department of Medicine, Emory University School of Medicine
                                                              Suma Shankar, MD, PhD
                                                              Adjunct Assistant Professor, Department of Ophthalmology, Emory University School of Medicine
                                                                Alicia K. Smith, PhD
                                                                Associate Professor and Vice Chair of Research, Department of Gynecology and Obstetrics, Emory University School of Medicine
                                                                  Samuel Speck, PhD
                                                                  Professor, Department of Microbiology and Immunology, Emory University School of Medicine
                                                                    Paula M. Vertino, PhD
                                                                    Professor, Department of Radiation Oncology, Emory University School of Medicine
                                                                      Ya Wang, PhD
                                                                      Director, Division of Experimental Radiation Oncology, Dept. of Radiation Oncology, Emory University School of Medicine
                                                                        Erica Werner, PhD
                                                                        Assistant Professor, Department of Biochemistry, Emory University School of Medicine
                                                                          William R. Wilcox, MD, PhD
                                                                          Professor, Department of Human Genetics, Emory University School of Medicine
                                                                            Keith D. Wilkinson, PhD
                                                                            Professor and Vice-Chair, Department of Biochemistry, Emory University School of Medicine
                                                                              Hao Wu, PhD, MHS, MS
                                                                              Assistant Professor, Department of Biostatistics and Bioinformatics, Emory University School of Medicine
                                                                                Bing Yao, PhD
                                                                                Assistant Professor, Department of Human Genetics, Emory University School of Medicine
                                                                                  David Yu, MD, PhD
                                                                                  Jerome Landry MD Chair of Cancer Biology and Associate Professor, Department of Radiation Oncology, Emory University School of Medicine
                                                                                    Linsheng Zhang, MD, PhD
                                                                                    Assistant Professor, Department of Pathology & Laboratory Medicine, Emory University School of Medicine
                                                                                      Wei Zhou, PhD
                                                                                      Professor, Department of Hematology and Medical Oncology, Emory University School of Medicine
                                                                                        Michael E. Zwick, PhD
                                                                                        Director, Emory Integrated Genomics Core, Emory University School of Medicine
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