Soma Sengupta, MD, PhD

Principal Investigator

Sengupta Lab

Assistant Professor, Department of Hematology and Medical Oncology

Emory University School of Medicine

Assistant Professor, Department of Neurology

Emory University School of Medicine

Assistant Professor, Department of Neurosurgery

Emory University School of Medicine

Education

  • PhD, Biochemistry, University of Cambridge, United Kingdom
  • MBBChir, Medicine, University of Cambridge, United Kingdom

Biography

I am a physician-scientist with a strong interest in treating patients, primarily adults, and participating in clinical trials. On the other hand, I am a committed "bench scientist" engaged in research that we hope will be translated speedily into the clinic.

I have a long-standing interest in membrane proteins and have worked on various channels, pumps, and transporters during my research career. I received early training in chemistry/biochemistry and conducted doctoral research at the University of Cambridge (U.K.) and the CNRS in Strasbourg, France; then post-doctoral training at Yale University.

I completed MBBChir training (equivalent to an MD) at the University of Cambridge and received Membership of the Royal College of Physicians (MRCP). I completed an internal medicine internship at Johns Hopkins, residency in neurology at BIDMC-Harvard, and a fellowship in neuro-oncology at Mass General and Dana-Farber.

I am a member of the Discovery and Developmental Therapeutics Research Program at Winship Cancer Institute. I am also a faculty member in the Neuroscience Graduate Program of the Graduate Division of Biological and Biomedical Sciences (GDBBS) at Emory Laney Graduate School. I hold professional memberships with the Royal College of Physicians (London, UK), the Society for Neuro-oncology and the American Academy of Neurology.

>>View Winship web profile.

Research

My strong research interest in medulloblastomas arose following my receipt of an R-25 (administered through the NINDS) to support my research efforts during the final year of my neurology residency (BIDMC-Harvard) and the first year of my neuro-oncology fellowship (MGH/DFCI/BWH-Harvard). My R-25 supported research, mentored by Drs. Jensen and Pomeroy (Boston Children's Hospital), was aimed at elucidating the importance of the GABA receptor GABRA5 in development and progression of medulloblastoma and to explore possible therapeutic interventions. This resulted in a publication. My research focus was a logical step for me as it built upon my long-standing interest and extensive research experience in membrane protein structure and function, conducted during doctoral research (University of Cambridge, U.K.), post-doctoral study (Yale University), as well as medical school and clinical training. Overall, I have conducted genetic and biochemical research on a broad range of eukaryotic membrane proteins that includes transporters, channels, and pumps. My mentors for the K08 while I was in Boston were Drs. S. Pomeroy, K. Ligon and N. Agar. However, after transferring to Emory, my K08 mentor is Dr. Tobey MacDonald.

Publications