Zachary Buchwald, MD, PhD

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Rating: 4.8 out of 5 (127 ratings)

Role

Radiation Oncology
Specialty

Skin Cancer and Melanoma
Research Program

Cancer Immunology
Practicing Since

2020

Call 404-778-3473

Background

Dr. Buchwald's primary clinical focus is radiation and immunotherapy for cutaneous malignancies.

Dr. Buchwald completed his PhD in Immunology and his MD in Medicine at St. Louis University in St. Louis, Missouri. He completed his residency in Radiation Oncology at Emory University School of Medicine in Atlanta, Georgia serving as co-chief resident in his final year. During residency, Dr. Buchwald completed a prestigious research fellowship, the Holman Pathway.

Dr. Buchwald is actively involved in both basic and clinical research. In his laboratory, he studies ways to enhance the immune response against melanoma and other cancers using radiation.

Titles & Roles

Assistant Professor, Department of Radiation Oncology

Emory University School of Medicine

Education & Training

Education

Residency, Radiation Oncology, 2020
Emory University School of Medicine
Internship, Internal Medicine, 2016
Emory University School of Medicine
Medical Education, MD, 2015
Saint Louis University School of Medicine

Research

View Current Clinical Trials


Comparing the Addition of Radiation Either Before or After Surgery for Patients With Brain Metastases Phase III Conditions Metastatic Malignant Neoplasm in the Brain Location Winship Cancer Institute
Radiosurgery Before Surgery for the Treatment of Brain Metastases Phase Early Phase I Conditions Metastatic Malignant Neoplasm in the Brain, Metastatic Malignant Solid Neoplasm Location Winship Cancer Institute

Grants

View Grants

Grant Number	Title
1K08CA270401-01A1	The role of stem-like CD8 T-cells in the abscopal response
1U54CA274513-01	P3: Molecular Mechanisms Underlying Therapy Response to Radiation and Immune Checkpoint BlockadeýSUBAWARD
5K12CA237806-05	Emory Clinical Oncology Career Development Award K12 Program
5U54CA274513-02	P3: Molecular Mechanisms Underlying Therapy Response to Radiation and Immune Checkpoint BlockadeýSUBAWARD

Publications

Dr. Buchwald has been published in a number of leading journals including Immunity, Cancer, JCI Insight, and Scientific Reports.

Title/Journal	Authors	Publication Date
Lymphatic vessel network injury reduces local tumor control despite preservation of the tumor-draining lymph node. Scientific reports	LN Liebman, Y Shen, ZS Buchwald, Z Nepiyushchikh, Z Qi, AJ García, JB Dixon	01/28/2025
Impact of race, ethnicity, and social determinants on outcomes following immune checkpoint therapy. Journal for immunotherapy of cancer	RK Nayak, M Aiello, LM Maldonado, TY Clark, ZS Buchwald, A Chang	10/26/2024
Pre-operative stereotactic radiosurgery and peri-operative dexamethasone for resectable brain metastases: a two-arm pilot study evaluating clinical outcomes and immunological correlates. Nature communications	CS Jansen, MS Pagadala, MA Cardenas, RS Prabhu, S Goyal, C Zhou, P Chappa, BT Vo, C Ye, B Hopkins, J Zhong, A Klie, T Daniels, M Admassu, I Green, NT Pfister, SG Neill, JM Switchenko, N Prokhnevska, KB Hoang, MA Torres, S Logan, JJ Olson, EK Nduom, L Del Balzo, K Patel, SH Burri, AL Asher, S Wilkinson, R Lake, AH Kesarwala, KA Higgins, P Patel, V Dhere, AG Sowalsky, H Carter, MK Khan, H Kissick, ZS Buchwald	10/14/2024
Drug's Journey of a Thousand Papers Begins With a Single Step. JCO clinical cancer informatics	PF Innominato, NI Wreglesworth, A Antonini, ZS Buchwald	10/01/2024
Pembrolizumab and low-dose, single-fraction radiotherapy for patients with relapsed or refractory multiple myeloma: a prospective, single-centre, single-group, open-label, phase 2 pilot trial in the USA. The Lancet. Haematology	MK Khan, TH Nasti, JY Qian, TJ Kleber, JM Switchenko, JL Kaufman, AJ Nooka, MV Dhodapkar, ZS Buchwald, D Obiekwe, S Lonial, R Ahmed	07/01/2024
Platinum-Based Chemotherapy Attenuates the Effector Response of CD8 T Cells to Concomitant PD-1 Blockade. Clinical cancer research : an official journal of the American Association for Cancer Research	A Mariniello, TH Nasti, DY Chang, M Hashimoto, S Malik, DT McManus, J Lee, DJ McGuire, MA Cardenas, P Umana, V Nicolini, R Antia, A Saha, Z Buchwald, H Kissick, E Ghorani, S Novello, D Sangiolo, GV Scagliotti, SS Ramalingam, R Ahmed	05/01/2024
Total scalp irradiation: A study comparing multiple types of bolus and VMAT optimization techniques. Journal of applied clinical medical physics	TM Davis, K Luca, LJ Sudmeier, ZS Buchwald, MK Khan, X Yang, E Schreibmann, J Zhang, J Roper	04/01/2024
Impact of immunotherapy time-of-day infusion on survival and immunologic correlates in patients with metastatic renal cell carcinoma: a multicenter cohort analysis. Journal for immunotherapy of cancer	JS Patel, Y Woo, A Draper, CS Jansen, JW Carlisle, PF Innominato, FA Lévi, L Dhabaan, VA Master, MA Bilen, MK Khan, MC Lowe, H Kissick, ZS Buchwald, DC Qian	03/26/2024
Radiation and anti-PD-L1 synergize by stimulating a stem-like T cell population in the tumor-draining lymph node. Research square	Y Shen, E Connolly, M Aiello, C Zhou, P Chappa, H Song, P Tippitak, T Clark, M Cardenas, N Prokhnevska, A Mariniello, MS Pagadala, VR Dhere, S Rafiq, AH Kesarwala, A Orthwein, SN Thomas, MK Khan, J Brandon Dixon, GB Lesinski, MC Lowe, H Kissick, DS Yu, CM Paulos, NC Schmitt, ZS Buchwald	03/06/2024
SAMHD1 expression contributes to doxorubicin resistance and predicts survival outcomes in diffuse large B-cell lymphoma patients. NAR cancer	W Daddacha, D Monroe, AJ Schlafstein, AE Withers, EB Thompson, D Danelia, NC Luong, F Sesay, SK Rath, ER Usoro, ME Essien, AT Jung, JG Jiang, J Hu, B Mahboubi, A Williams, JE Steinbeck, X Yang, ZS Buchwald, WS Dynan, JM Switchenko, B Kim, MK Khan, DL Jaye, DS Yu	03/01/2024
The Deubiquitylase Otub1 Regulates the Chemotactic Response of Splenic B Cells by Modulating the Stability of the γ-Subunit Gng2. Molecular and cellular biology	VM Luo, C Shen, S Worme, A Bhagrath, E Simo-Cheyou, S Findlay, S Hébert, W Wai Lam Poon, Z Aryanpour, T Zhang, RP Zahedi, J Boulais, ZS Buchwald, CH Borchers, JF Côté, CL Kleinman, JN Mandl, A Orthwein	01/01/2024
CD28-CD57+ T cells from head and neck cancer patients produce high levels of cytotoxic granules and type II interferon but are not senescent. Oncoimmunology	BLC Kinney, B Brammer, V Kansal, CJ Parrish, HT Kissick, Y Liu, NF Saba, ZS Buchwald, MW El-Deiry, MR Patel, BJ Boyce, AS Kaka, JH Gross, HM Baddour, AY Chen, NC Schmitt	01/01/2024
The expanding role of IAP antagonists for the treatment of head and neck cancer. Cancer medicine	V Kansal, BLC Kinney, S Uppada, NF Saba, WA Stokes, ZS Buchwald, NC Schmitt	07/01/2023
Immune niches in brain metastases contain TCF1+ stem-like T cells, are associated with disease control and are modulated by preoperative SRS. Research square	CS Jansen, RS Prabhu, MS Pagadala, P Chappa, S Goyal, C Zhou, SG Neill, N Prokhnevska, M Cardenas, KB Hoang, J Zhong, M Torres, S Logan, JJ Olson, EK Nduom, L Del Balzo, K Patel, SH Burri, AL Asher, S Wilkinson, R Lake, KA Higgins, P Patel, V Dhere, AG Sowalsky, MK Khan, H Kissick, ZS Buchwald	03/23/2023
Statin drugs enhance responses to immune checkpoint blockade in head and neck cancer models. Journal for immunotherapy of cancer	V Kansal, AJ Burnham, BLC Kinney, NF Saba, C Paulos, GB Lesinski, ZS Buchwald, NC Schmitt	01/01/2023
Immune checkpoint inhibitors and timing of administration - Authors' reply. The Lancet. Oncology	DC Qian, ZS Buchwald	02/01/2022
Skin Microbiome and Treatment-Related Skin Toxicities in Patients With Cancer: A Mini-Review. Frontiers in oncology	BN Richardson, J Lin, ZS Buchwald, J Bai	01/01/2022
Effect of immunotherapy time-of-day infusion on overall survival among patients with advanced melanoma in the USA (MEMOIR): a propensity score-matched analysis of a single-centre, longitudinal study. The Lancet. Oncology	DC Qian, T Kleber, B Brammer, KM Xu, JM Switchenko, JR Janopaul-Naylor, J Zhong, ML Yushak, RD Harvey, CM Paulos, DH Lawson, MK Khan, RR Kudchadkar, ZS Buchwald	12/01/2021
The Abscopal Effect: A Review of Pre-Clinical and Clinical Advances. International journal of molecular sciences	JR Janopaul-Naylor, Y Shen, DC Qian, ZS Buchwald	10/14/2021
Immunotherapeutic Strategies for Head and Neck Cancer. Otolaryngologic clinics of North America	ZS Buchwald, NC Schmitt	08/01/2021
Immunomodulatory Low-Dose Whole-Lung Radiation for Patients with Coronavirus Disease 2019-Related Pneumonia. International journal of radiation oncology, biology, physics	CB Hess, TH Nasti, VR Dhere, TJ Kleber, JM Switchenko, ZS Buchwald, WA Stokes, BD Weinberg, N Rouphael, JP Steinberg, KD Godette, DJ Murphy, R Ahmed, WJ Curran, MK Khan	03/15/2021
Leptomeningeal disease and neurologic death after surgical resection and radiosurgery for brain metastases: A multi-institutional analysis. Advances in radiation oncology	RS Prabhu, BE Turner, AL Asher, SR Marcrom, JB Fiveash, PM Foreman, RH Press, ZS Buchwald, WJ Curran, KR Patel, WG Breen, PD Brown, KR Jethwa, IS Grills, JD Arden, LM Foster, MA Manning, ZK Vaslow, SH Burri, SG Soltys	01/01/2021
The Association Between Radiation Therapy Dose and Overall Survival in Patients With Intracranial Infiltrative Low-Grade Glioma Treated With Concurrent and/or Adjuvant Chemotherapy. Advances in radiation oncology	RS Prabhu, MC Ward, JH Heinzerling, CD Corso, ZS Buchwald, R Dhakal, AL Asher, AL Sumrall, SH Burri	01/01/2021
Immunomodulatory Low-Dose Whole-Lung Radiation for Patients with COVID-19-Related Pneumonia. International journal of radiation oncology, biology, physics	CB Hess, ZS Buchwald, WA Stokes, T Nasti, J Switchenko, BD Weinberg, N Rouphael, JP Steinberg, KD Godette, DJ Murphy, R Ahmed, WJ Curran, MK Khan	12/01/2020
Lung Stereotactic Body Radiation Therapy and Concurrent Immunotherapy: A Multicenter Safety and Toxicity Analysis. International journal of radiation oncology, biology, physics	S Tian, JM Switchenko, ZS Buchwald, PR Patel, JW Shelton, SE Kahn, RN Pillai, CE Steuer, TK Owonikoko, M Behera, WJ Curran, KA Higgins	09/01/2020
Moderately Hypofractionated Radiation for Benign Meningiomas and Schwannomas: A Report of 70 Patients Treated Between 2008 and 2018. Advances in radiation oncology	VR Dhere, S Tian, Z Buchwald, X Jiang, C Zhang, Z Chen, BR Eaton, HG Shu, WJ Curran, J Zhong	01/01/2020

Ratings & Reviews

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4.9	One star One star One star One star One half star	Provider showed concern
4.8	One star One star One star One star One half star	Provider explained things clearly
4.8	One star One star One star One star One half star	Provider discussed treatment options
4.8	One star One star One star One star One half star	Provider included you in decisions
4.8	One star One star One star One star One half star	Likelihood of recommending this provider

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One star One star One star One star One star	11/16/2024	Outstanding clinician
One star One star One star One star One star	11/06/2024	Dr. Buchwald is amazing
One star One star One star One star One star	10/27/2024	Excellent care
One star One star One star One star One star	09/14/2024	Provided candor, detail, and expectations in a terrific way. Made me trust his recommendations and guidance.
One star One star One star One star One star	06/15/2024	Nice people
One star One star One star One star One star	03/09/2024	Very comforting.
One star One star One star One star One star	02/06/2024	Professional
One star One star One star One star One star	01/09/2024	Good
One star One star One star One star One star	09/16/2023	Dr Buchwald is a knowledgeable , compassionate and caring doctor . He is the best doctor I've ever worked with .
One star One star One star One star One star	08/07/2023	Dr. Buchwald was very thorough in our discussions of Radiation versus Proton Therapy and after our visit we made the decision to stay at Emory Clifton and start the treatments with him.
One star One star One star One star One star	06/20/2023	For me everything went well
One star One star One star One star One star	05/27/2023	Dr Buckwald was awesome