Mark Goodman, PhD

Research Program

Discovery and Developmental Therapeutics
Phone Number

404-727-9366
Email Address

mgoodma@emory.edu

Biography

Arriving at Emory in 1993, Mark M. Goodman, PhD, is Professor of Radiology and Imaging Sciences, Psychiatry and Hematology and Oncology Tracer Development At Emory University School of Medicine and Program Director of the Emory Center for Systems Imaging and Director of the Radiopharmaceutical Discovery Lab.

After working as a chemist at Roswell Park Cancer Institute, Dr. Goodman joined the Department of Radiology at Harvard University in 1978 to pursue the development of positron emitting carbohydrates and fatty acids. In fall 1980, he took a position as a staff scientist at Oak Ridge National Laboratory and worked on the development of single photon labeled fatty acids and carbohydrates. Dr. Goodman's research led to the development of the methylbranched fatty acid [123I] BMIPP, which has been commercially introduced in Japan as Cardiodine. In 1987, Dr. Goodman moved to the University of Tennessee Medical Center at Knoxville where he took the position of Associate Professor of Radiology and Director of Radiopharmaceutical Chemistry to help establish the University of Tennessee PET program. At the University of Tennessee, he developed the dopamine transporter imaging agents [18F] FPCT, [123I] MMG-142/IPT and translated [11C] ACBC to image brain tumors in humans. He was promoted to Professor of Radiology in 1993.

Education

Dr. Goodman received his bachelor’s degree in chemistry from Monmouth College and his doctorate in organic chemistry from the University of Alabama. He continued his education with several post-doctoral Fellowships from the University of Alabama, Yale University and Harvard University.

Titles & Roles

Professor, Radiology, Psychiatry and Hematology and Oncology

Emory University School of Medicine

Research

Dr. Goodman’s research interests encompass positron emission tomography (PET) and single photon emission computed tomography (SPECT) radiotracer development of oncology, brain and heart agents. His research has resulted in the translation of the first reported synthetic amino alicyclic acid radio labeled with the PET radioelement fluorine-18 for imaging both intracranial tumors and prostate cancer in patients. In applied research, Dr. Goodman’s interests include the development of automated devices to facilitate the use of new radiotracers in clinical medicine.

Grants

View Grants

Grant Number	Title
5R01EB029320-04	Imaging bacterial infections with 2nd generation maltodextrins
5R21CA259935-02	PET Imaging Agents for Protoporphyrin IX
5R42AI157552-03	Imaging Bacterial Infections in Vivo: First in Man Studies

Publications

Title/Journal	Authors	Publication Date
Synthetic Efforts toward the Synthesis of a Fluorinated Analog of 5-Aminolevulinic Acid: Practical Synthesis of Racemic and Enantiomerically Defined 3-Fluoro-5-aminolevulinic Acid. The Journal of organic chemistry	G Pashikanti, LN Chavan, LS Liebeskind, MM Goodman	09/06/2024
Alterations in adolescent brain serotonin (5HT)_1A, 5HT_2A, and dopamine (D)₂ receptor systems in a nonhuman primate model of early life adversity. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology	AGP Wakeford, JA Nye, EL Morin, J Mun, JS Meyer, M Goodman, LL Howell, MM Sanchez	07/01/2024
Isothermal titration calorimetry analysis of the binding between the maltodextrin binding protein malE of Staphylococcus aureus with maltodextrins of various lengths. Biochemical and biophysical research communications	K Takemiya, S Wang, Y Liu, N Murthy, MM Goodman, WR Taylor	02/05/2024
Concise and Scalable Radiosynthesis of (+)-[¹⁸F]MDL100907 as a Serotonin 5-HT_2A Receptor Antagonist for PET. ACS chemical neuroscience	LN Chavan, R Voll, MM Sanchez, JA Nye, MM Goodman	10/04/2023
PET imaging of dopamine transporters and D2/D3 receptors in female monkeys: effects of chronic cocaine self-administration. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology	MI Allen, AN Duke, SH Nader, A Adler-Neal, KK Solingapuram Sai, BA Reboussin, HD Gage, RJ Voll, A Mintz, MM Goodman, MA Nader	09/01/2023
Impact of 18 F-Fluciclovine PET/CT Findings on Failure-Free Survival in Biochemical Recurrence of Prostate Cancer Following Salvage Radiation Therapy. Clinical nuclear medicine	IO Lawal, C Marcus, DM Schuster, S Goyal, OA Adediran, VR Dhere, SS Joshi, OA Abiodun-Ojo, VA Master, PR Patel, B Fielder, M Goodman, JW Shelton, O Kucuk, B Hershatter, RK Halkar, AB Jani	04/01/2023
Differences in Failure-Free Survival After Salvage Radiotherapy Guided by Conventional Imaging Versus ¹⁸F-Fluciclovine PET/CT in Postprostatectomy Patients: A Post Hoc Substratification Analysis of the EMPIRE-1 Trial. Journal of nuclear medicine : official publication, Society of Nuclear Medicine	IO Lawal, AB Jani, OA Adediran, S Goyal, OA Abiodun-Ojo, VR Dhere, CV Marcus, SS Joshi, VA Master, PR Patel, M Goodman, JW Shelton, O Kucuk, B Hershatter, B Fielder, RK Halkar, DM Schuster	04/01/2023
Effect of sex and autism spectrum disorder on oxytocin receptor binding and mRNA expression in the dopaminergic pars compacta of the human substantia nigra. Philosophical transactions of the Royal Society of London. Series B, Biological sciences	SS Frehner, KT Dooley, MC Palumbo, AL Smith, MM Goodman, KL Bales, SM Freeman	08/29/2022
High Prediagnosis Inflammation-Related Risk Score Associated with Decreased Ovarian Cancer Survival. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology	KK Brieger, MT Phung, B Mukherjee, KM Bakulski, H Anton-Culver, EV Bandera, DDL Bowtell, DW Cramer, A DeFazio, JA Doherty, S Fereday, RT Fortner, A Gentry-Maharaj, EL Goode, MT Goodman, HR Harris, K Matsuo, U Menon, F Modugno, KB Moysich, B Qin, SJ Ramus, HA Risch, MA Rossing, JM Schildkraut, B Trabert, RA Vierkant, SJ Winham, N Wentzensen, AH Wu, A Ziogas, L Khoja, KR Cho, K McLean, J Richardson, B Grout, A Chase, CM Deurloo, K Odunsi, BH Nelson, JD Brenton, KL Terry, PDP Pharoah, A Berchuck, GE Hanley, PM Webb, MC Pike, CL Pearce	02/01/2022
A Swine Hind Limb Ischemia Model Useful for Testing Peripheral Artery Disease Therapeutics. Journal of cardiovascular translational research	JN Deppen, SC Ginn, NH Kim, L Wang, RJ Voll, SH Liang, MM Goodman, JN Oshinski, RD Levit	12/01/2021
Salvage Radiotherapy Management Decisions in Postprostatectomy Patients with Recurrent Prostate Cancer Based on ¹⁸F-Fluciclovine PET/CT Guidance. Journal of nuclear medicine : official publication, Society of Nuclear Medicine	OA Abiodun-Ojo, AB Jani, AA Akintayo, OO Akin-Akintayo, OA Odewole, FI Tade, SS Joshi, VA Master, B Fielder, RK Halkar, C Zhang, S Goyal, MM Goodman, DM Schuster	08/01/2021
Targeting HIF-activated collagen prolyl 4-hydroxylase expression disrupts collagen deposition and blocks primary and metastatic uveal melanoma growth. Oncogene	S Kaluz, Q Zhang, Y Kuranaga, H Yang, S Osuka, D Bhattacharya, NS Devi, J Mun, W Wang, R Zhang, MM Goodman, HE Grossniklaus, EG Van Meir	08/01/2021
Synthesis, Radiolabeling, and Biological Evaluation of the trans-Stereoisomers of 1-Amino-3-(fluoro-¹⁸F)-4-fluorocyclopentane-1-carboxylic Acid as PET Imaging Agents. ACS pharmacology & translational science	TC Pickel, G Pashikanti, RJ Voll, W Yu, Z Zhang, JA Nye, J Bacsa, JJ Olson, LS Liebeskind, MM Goodman	06/11/2021
¹⁸F-fluciclovine-PET/CT imaging versus conventional imaging alone to guide postprostatectomy salvage radiotherapy for prostate cancer (EMPIRE-1): a single centre, open-label, phase 2/3 randomised controlled trial. Lancet (London, England)	AB Jani, E Schreibmann, S Goyal, R Halkar, B Hershatter, PJ Rossi, JW Shelton, PR Patel, KM Xu, M Goodman, VA Master, SS Joshi, O Kucuk, BC Carthon, MA Bilen, OA Abiodun-Ojo, AA Akintayo, VR Dhere, DM Schuster	05/22/2021
Depot-Medroxyprogesterone Acetate Use Is Associated with Decreased Risk of Ovarian Cancer: The Mounting Evidence of a Protective Role of Progestins. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology	MT Phung, AW Lee, AH Wu, A Berchuck, KR Cho, DW Cramer, JA Doherty, MT Goodman, GE Hanley, HR Harris, K McLean, F Modugno, KB Moysich, B Mukherjee, JM Schildkraut, KL Terry, LJ Titus, SJ Jordan, PM Webb, MC Pike, CL Pearce	05/01/2021
Sunburn frequency and risk and protective factors: a cross-sectional survey. Dermatology online journal	HA Braun, CH Adler, M Goodman, H Yeung	04/15/2021
Synthesis and Evaluation of [¹¹C]7-Halogen-2-Phenyl Isoindolone Derivatives: Potential PET Radioligands for in vivo Imaging of 5-HT₂_C Receptors. Frontiers in neuroscience	F Zeng, JA Nye, RJ Voll, J Mun, MM Goodman	01/01/2021
Maltohexaose-indocyanine green (MH-ICG) for near infrared imaging of endocarditis. PloS one	K Takemiya, JJ Røise, M He, C Taing, AG Rodriguez, N Murthy, MM Goodman, WR Taylor	01/01/2021
[¹⁸F]-Fluciclovine PET discrimination of recurrent intracranial metastatic disease from radiation necrosis. EJNMMI research	EE Parent, D Patel, JA Nye, Z Li, JJ Olson, DM Schuster, MM Goodman	12/07/2020
Initial Report of a Randomized Trial Comparing Conventional- vs Conventional plus Fluciclovine (¹⁸F) PET/CT Imaging-Guided Post-Prostatectomy Radiotherapy for Prostate Cancer. International journal of radiation oncology, biology, physics	A Jani, E Schreibmann, S Goyal, H Raghuveer, B Hershatter, PJ Rossi, JW Shelton, PR Patel, KM Xu, M Goodman, V Master, SS Joshi, O Kucuk, B Carthon, MA Bilen, S Cooper, B Fielder, O Abiodun-Ojo, VR Dhere, DM Schuster	12/01/2020
Synthesis, Radiolabeling, and Biological Evaluation of the cis Stereoisomers of 1-Amino-3-Fluoro-4-(fluoro-¹⁸F)Cyclopentane-1-Carboxylic Acid as PET Imaging Agents. Journal of medicinal chemistry	TC Pickel, RJ Voll, W Yu, Z Wang, JA Nye, J Bacsa, JJ Olson, LS Liebeskind, MM Goodman	10/22/2020
Erratum to "Synthesis, F-18 radiolabeling, and microPET evaluation of 3-(2,4-dichlorophenyl)-N-alkyl-N-fluoroalkyl-2,5-dimethylpyrazolo[1,5-a]pyrimidin-7-amines as ligands of the corticotropin-releasing factor type-1 (CRF1) receptor" [Bioorg. Med. Chem. 23 (2015) 4286-4302]. Bioorganic & medicinal chemistry	JS Stehouwer, MS Birnbaum, RJ Voll, MJ Owens, SJ Plott, CH Bourke, MA Wassef, CD Kilts, MM Goodman	10/01/2020
Microglia, inflammation and gut microbiota responses in a progressive monkey model of Parkinson's disease: A case series. Neurobiology of disease	V Joers, G Masilamoni, D Kempf, AR Weiss, TM Rotterman, B Murray, G Yalcin-Cakmakli, RJ Voll, MM Goodman, L Howell, J Bachevalier, SJ Green, A Naqib, M Shaikh, PA Engen, A Keshavarzian, CJ Barnum, JA Nye, Y Smith, MG Tansey	10/01/2020
[¹⁸F]Fluciclovine Positron Emission Tomography/Computerized Tomography for Preoperative Staging in Patients with Intermediate to High Risk Primary Prostate Cancer. The Journal of urology	M Alemozaffar, AA Akintayo, OA Abiodun-Ojo, D Patil, F Saeed, Y Huang, AO Osunkoya, MM Goodman, M Sanda, DM Schuster	10/01/2020
Adaptive Validation Design: A Bayesian Approach to Validation Substudy Design With Prospective Data Collection. Epidemiology (Cambridge, Mass.)	LJ Collin, RF MacLehose, TP Ahern, R Nash, D Getahun, D Roblin, MJ Silverberg, M Goodman, TL Lash	07/01/2020
Sexual and Gender Minority Populations and Skin Cancer-New Data and Renewed Priorities. JAMA dermatology	H Yeung, H Braun, M Goodman	04/01/2020
A benzenesulfonamide derivative as a novel PET radioligand for CXCR4. Bioorganic & medicinal chemistry	YH Oum, D Shetty, Y Yoon, Z Liang, RJ Voll, MM Goodman, H Shim	01/15/2020
¹⁸F-Fluciclovine Parameters on Targeted Prostate Biopsy Associated with True Positivity in Recurrent Prostate Cancer. Journal of nuclear medicine : official publication, Society of Nuclear Medicine	OA Abiodun-Ojo, AA Akintayo, OO Akin-Akintayo, FI Tade, PT Nieh, VA Master, M Alemozaffar, AO Osunkoya, MM Goodman, B Fei, DM Schuster	11/01/2019
Publisher Correction: Shared heritability and functional enrichment across six solid cancers. Nature communications	X Jiang, HK Finucane, FR Schumacher, SL Schmit, JP Tyrer, Y Han, K Michailidou, C Lesseur, KB Kuchenbaecker, J Dennis, DV Conti, G Casey, MM Gaudet, JR Huyghe, D Albanes, MC Aldrich, AS Andrew, IL Andrulis, H Anton-Culver, AC Antoniou, NN Antonenkova, SM Arnold, KJ Aronson, BK Arun, EV Bandera, RB Barkardottir, DR Barnes, J Batra, MW Beckmann, J Benitez, S Benlloch, A Berchuck, SI Berndt, H Bickeböller, SA Bien, C Blomqvist, S Boccia, NV Bogdanova, SE Bojesen, MK Bolla, H Brauch, H Brenner, JD Brenton, MN Brook, J Brunet, H Brunnström, DD Buchanan, B Burwinkel, R Butzow, G Cadoni, T Caldés, MA Caligo, I Campbell, PT Campbell, G Cancel-Tassin, L Cannon-Albright, D Campa, N Caporaso, AL Carvalho, AT Chan, J Chang-Claude, SJ Chanock, C Chen, DC Christiani, KBM Claes, F Claessens, J Clements, JM Collée, MC Correa, FJ Couch, A Cox, JM Cunningham, C Cybulski, K Czene, MB Daly, A deFazio, P Devilee, O Diez, M Gago-Dominguez, JL Donovan, T Dörk, EJ Duell, AM Dunning, M Dwek, DM Eccles, CK Edlund, DRV Edwards, C Ellberg, DG Evans, PA Fasching, RL Ferris, T Liloglou, JC Figueiredo, O Fletcher, RT Fortner, F Fostira, S Franceschi, E Friedman, SJ Gallinger, PA Ganz, J Garber, JA García-Sáenz, SA Gayther, GG Giles, AK Godwin, MS Goldberg, DE Goldgar, EL Goode, MT Goodman, G Goodman, K Grankvist, MH Greene, H Gronberg, J Gronwald, P Guénel, N Håkansson, P Hall, U Hamann, FC Hamdy, RJ Hamilton, J Hampe, A Haugen, F Heitz, R Herrero, P Hillemanns, M Hoffmeister, E Høgdall, YC Hong, JL Hopper, R Houlston, PJ Hulick, DJ Hunter, DG Huntsman, G Idos, EN Imyanitov, SA Ingles, C Isaacs, A Jakubowska, P James, MA Jenkins, M Johansson, M Johansson, EM John, AD Joshi, R Kaneva, BY Karlan, LE Kelemen, T Kühl, KT Khaw, E Khusnutdinova, AS Kibel, LA Kiemeney, J Kim, SK Kjaer, JA Knight, M Kogevinas, Z Kote-Jarai, S Koutros, VN Kristensen, J Kupryjanczyk, M Lacko, S Lam, D Lambrechts, MT Landi, P Lazarus, ND Le, E Lee, F Lejbkowicz, HJ Lenz, G Leslie, D Lessel, J Lester, DA Levine, L Li, CI Li, A Lindblom, NM Lindor, G Liu, F Loupakis, J Lubiński, L Maehle, C Maier, A Mannermaa, LL Marchand, S Margolin, T May, L McGuffog, A Meindl, P Middha, A Miller, RL Milne, RJ MacInnis, F Modugno, M Montagna, V Moreno, KB Moysich, L Mucci, K Muir, AM Mulligan, KL Nathanson, DE Neal, AR Ness, SL Neuhausen, H Nevanlinna, PA Newcomb, LF Newcomb, FC Nielsen, L Nikitina-Zake, BG Nordestgaard, RL Nussbaum, K Offit, E Olah, AAA Olama, OI Olopade, AF Olshan, H Olsson, A Osorio, H Pandha, JY Park, N Pashayan, MT Parsons, T Pejovic, KL Penney, WHM Peters, CM Phelan, AI Phipps, D Plaseska-Karanfilska, M Pring, D Prokofyeva, P Radice, K Stefansson, SJ Ramus, L Raskin, G Rennert, HS Rennert, EJ van Rensburg, MJ Riggan, HA Risch, A Risch, MJ Roobol, BS Rosenstein, MA Rossing, K De Ruyck, E Saloustros, DP Sandler, EJ Sawyer, MB Schabath, J Schleutker, MK Schmidt, VW Setiawan, H Shen, EM Siegel, W Sieh, CF Singer, ML Slattery, KD Sorensen, MC Southey, AB Spurdle, JL Stanford, VL Stevens, S Stintzing, J Stone, K Sundfeldt, R Sutphen, AJ Swerdlow, EH Tajara, CM Tangen, A Tardon, JA Taylor, MD Teare, MR Teixeira, MB Terry, KL Terry, SN Thibodeau, M Thomassen, L Bjørge, M Tischkowitz, AE Toland, D Torres, PA Townsend, RC Travis, N Tung, SS Tworoger, CM Ulrich, N Usmani, CM Vachon, E Van Nieuwenhuysen, A Vega, ME Aguado-Barrera, Q Wang, PM Webb, CR Weinberg, S Weinstein, MC Weissler, JN Weitzel, CML West, E White, AS Whittemore, HE Wichmann, F Wiklund, R Winqvist, A Wolk, P Woll, M Woods, AH Wu, X Wu, D Yannoukakos, W Zheng, S Zienolddiny, A Ziogas, KK Zorn, JM Lane, R Saxena, D Thomas, RJ Hung, B Diergaarde, J McKay, U Peters, L Hsu, M García-Closas, RA Eeles, G Chenevix-Trench, PJ Brennan, CA Haiman, J Simard, DF Easton, SB Gruber, PDP Pharoah, AL Price, B Pasaniuc, CI Amos, P Kraft, S Lindström	09/23/2019
The association of late-life depression with all-cause and cardiovascular mortality among community-dwelling older adults: systematic review and meta-analysis. The British journal of psychiatry : the journal of mental science	J Wei, R Hou, X Zhang, H Xu, L Xie, EK Chandrasekar, M Ying, M Goodman	08/01/2019
Feasibility and Initial Results: Fluciclovine Positron Emission Tomography/Ultrasound Fusion Targeted Biopsy of Recurrent Prostate Cancer. The Journal of urology	B Fei, OA Abiodun-Ojo, AA Akintayo, O Akin-Akintayo, F Tade, PT Nieh, VA Master, M Alemozaffar, AO Osunkoya, MM Goodman, DM Schuster	08/01/2019
Novel PET and Near Infrared Imaging Probes for the Specific Detection of Bacterial Infections Associated With Cardiac Devices. JACC. Cardiovascular imaging	K Takemiya, X Ning, W Seo, X Wang, R Mohammad, G Joseph, JS Titterington, CS Kraft, JA Nye, N Murthy, MM Goodman, WR Taylor	05/01/2019
Effect of age and autism spectrum disorder on oxytocin receptor density in the human basal forebrain and midbrain. Translational psychiatry	SM Freeman, MC Palumbo, RH Lawrence, AL Smith, MM Goodman, KL Bales	12/04/2018
Selective modification of fluciclovine (¹⁸F) transport in prostate carcinoma xenografts. Amino acids	FI Tade, WG Wiles, G Lu, B Bilir, O Akin-Akintayo, JS Lee, D Patil, W Yu, C Ormenisan Gherasim, B Fei, CS Moreno, AO Osunkoya, EJ Teoh, S Oka, H Okudaira, MM Goodman, DM Schuster	09/01/2018
[¹⁸F]Fluciclovine PET discrimination between high- and low-grade gliomas. EJNMMI research	EE Parent, M Benayoun, I Ibeanu, JJ Olson, CG Hadjipanayis, DJ Brat, V Adhikarla, J Nye, DM Schuster, MM Goodman	07/25/2018
Prospective evaluation of fluciclovine (¹⁸F) PET-CT and MRI in detection of recurrent prostate cancer in non-prostatectomy patients. European journal of radiology	O Akin-Akintayo, F Tade, P Mittal, C Moreno, PT Nieh, P Rossi, D Patil, R Halkar, B Fei, V Master, AB Jani, H Kitajima, AO Osunkoya, C Ormenisan-Gherasim, MM Goodman, DM Schuster	05/01/2018
Synthesis and Evaluation of Pyridyloxypyridyl Indole Carboxamides as Potential PET Imaging Agents for 5-HT_2C Receptors. ACS medicinal chemistry letters	F Zeng, JA Nye, RJ Voll, L Howell, MM Goodman	03/08/2018
Synthesis and biological properties of radiohalogenated α,α-disubstituted amino acids for PET and SPECT imaging of amino acid transporters (AATs). Journal of labelled compounds & radiopharmaceuticals	MM Goodman, W Yu, N Jarkas	03/01/2018
Re(CO)₃([¹⁸F]FEDA), a novel ¹⁸F PET renal tracer: Radiosynthesis and preclinical evaluation. Nuclear medicine and biology	M Lipowska, N Jarkas, RJ Voll, JA Nye, J Klenc, MM Goodman, AT Taylor	03/01/2018
Test-Retest Reliability of the SERT Imaging Agent ¹¹C-HOMADAM in Healthy Humans. Journal of nuclear medicine : official publication, Society of Nuclear Medicine	V Adhikarla, BW Dunlop, N Jarkas, MM Goodman, H Mayberg, MJ Owens, JA Nye	02/01/2018
Radiochemical Synthesis and Evaluation of ¹³N-Labeled 5-Aminolevulinic Acid for PET Imaging of Gliomas. ACS medicinal chemistry letters	AB Pippin, RJ Voll, Y Li, H Wu, H Mao, MM Goodman	12/14/2017
Using multiple biomarkers and determinants to obtain a better measurement of oxidative stress: a latent variable structural equation model approach. Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals	RC Eldridge, WD Flanders, RM Bostick, V Fedirko, M Gross, B Thyagarajan, M Goodman	09/01/2017
DNA base excision repair genetic risk scores, oxidative balance, and incident, sporadic colorectal adenoma. Molecular carcinogenesis	T Wang, M Goodman, YV Sun, B Thyagarajan, M Gross, RM Bostick	06/01/2017
Fasting Enhances the Contrast of Bone Metastatic Lesions in ¹⁸F-Fluciclovine-PET: Preclinical Study Using a Rat Model of Mixed Osteolytic/Osteoblastic Bone Metastases. International journal of molecular sciences	S Oka, M Kanagawa, Y Doi, DM Schuster, MM Goodman, H Yoshimura	04/29/2017
Selective localization of oxytocin receptors and vasopressin 1a receptors in the human brainstem. Social neuroscience	SM Freeman, AL Smith, MM Goodman, KL Bales	04/01/2017
Impact of ¹⁸F-Fluciclovine PET on Target Volume Definition for Postprostatectomy Salvage Radiotherapy: Initial Findings from a Randomized Trial. Journal of nuclear medicine : official publication, Society of Nuclear Medicine	AB Jani, E Schreibmann, PJ Rossi, J Shelton, K Godette, P Nieh, VA Master, O Kucuk, M Goodman, R Halkar, S Cooper, Z Chen, DM Schuster	03/01/2017
Multisite Experience of the Safety, Detection Rate and Diagnostic Performance of Fluciclovine (¹⁸F) Positron Emission Tomography/Computerized Tomography Imaging in the Staging of Biochemically Recurrent Prostate Cancer. The Journal of urology	T Bach-Gansmo, C Nanni, PT Nieh, L Zanoni, TV Bogsrud, H Sletten, KA Korsan, J Kieboom, FI Tade, O Odewole, A Chau, P Ward, MM Goodman, S Fanti, DM Schuster, F Willoch	03/01/2017
Non-ampullary-duodenal carcinomas: clinicopathologic analysis of 47 cases and comparison with ampullary and pancreatic adenocarcinomas. Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc	Y Xue, A Vanoli, S Balci, MM Reid, B Saka, P Bagci, B Memis, H Choi, N Ohike, T Tajiri, T Muraki, B Quigley, BF El-Rayes, W Shaib, D Kooby, J Sarmiento, SK Maithel, JH Knight, M Goodman, AM Krasinskas, V Adsay	02/01/2017
An evaluation of central penetration from a peripherally administered oxytocin receptor selective antagonist in nonhuman primates. Bioorganic & medicinal chemistry	AL Smith, H Walum, F Connor-Stroud, SM Freeman, K Inoue, LA Parr, MM Goodman, LJ Young	01/01/2017
Change in Salvage Radiotherapy Management Based on Guidance With FACBC (Fluciclovine) PET/CT in Postprostatectomy Recurrent Prostate Cancer. Clinical nuclear medicine	OO Akin-Akintayo, AB Jani, O Odewole, FI Tade, PT Nieh, VA Master, LM Bellamy, RK Halkar, C Zhang, Z Chen, MM Goodman, DM Schuster	01/01/2017
PET Tracer ¹⁸F-Fluciclovine Can Detect Histologically Proven Bone Metastatic Lesions: A Preclinical Study in Rat Osteolytic and Osteoblastic Bone Metastasis Models. Theranostics	S Oka, M Kanagawa, Y Doi, DM Schuster, MM Goodman, H Yoshimura	01/01/2017
Pediatric quality of life in long-term survivors of childhood cancer treated with anthracyclines. Pediatric blood & cancer	AB Ryerson, K Wasilewski-Masker, WL Border, M Goodman, L Meacham, H Austin, JG Marchak, AC Mertens	12/01/2016
Recurrent prostate cancer detection with anti-3-[(18)F]FACBC PET/CT: comparison with CT. European journal of nuclear medicine and molecular imaging	OA Odewole, FI Tade, PT Nieh, B Savir-Baruch, AB Jani, VA Master, PJ Rossi, RK Halkar, AO Osunkoya, O Akin-Akintayo, C Zhang, Z Chen, MM Goodman, DM Schuster	09/01/2016
Anti-3-18F-FACBC (18F-Fluciclovine) PET/CT of Breast Cancer: An Exploratory Study. Journal of nuclear medicine : official publication, Society of Nuclear Medicine	FI Tade, MA Cohen, TM Styblo, OA Odewole, AI Holbrook, MS Newell, B Savir-Baruch, X Li, MM Goodman, JA Nye, DM Schuster	09/01/2016
Initial investigation of three selective and potent small molecule oxytocin receptor PET ligands in New World monkeys. Bioorganic & medicinal chemistry letters	AL Smith, SM Freeman, TE Barnhart, DH Abbott, EO Ahlers, DL Kukis, KL Bales, MM Goodman, LJ Young	07/15/2016
Cardiometabolic Risk Factor Changes Observed in Diabetes Prevention Programs in US Settings: A Systematic Review and Meta-analysis. PLoS medicine	U Mudaliar, A Zabetian, M Goodman, JB Echouffo-Tcheugui, AL Albright, EW Gregg, MK Ali	07/01/2016
In Vitro Metabolic Stability and in Vivo Biodistribution of 3-Methyl-4-furoxancarbaldehyde Using PET Imaging in Rats. ACS medicinal chemistry letters	AB Pippin, ZH Mohd Arshad, RJ Voll, JA Nye, S Ghassabian, CM Williams, A Mancini, DC Liotta, MT Smith, MM Goodman	06/09/2016
Compartmental modeling of [(11)C]MENET binding to the norepinephrine transporter in the healthy human brain. Nuclear medicine and biology	V Adhikarla, F Zeng, JR Votaw, MM Goodman, JA Nye	05/01/2016
Reproducibility and reliability of anti-3-[¹⁸F]FACBC uptake measurements in background structures and malignant lesions on follow-up PET-CT in prostate carcinoma: an exploratory analysis. Molecular imaging and biology	OA Odewole, OA Oyenuga, F Tade, B Savir-Baruch, PT Nieh, V Master, Z Chen, X Wang, AB Jani, LM Bellamy, RK Halkar, MM Goodman, DM Schuster	04/01/2015
Video-based educational tool improves patient comprehension of common prostate health terminology. Cancer	DS Wang, AB Jani, M Sesay, CG Tai, DK Lee, KV Echt, MG Goodman, KE Kilbridge, VA Master	03/01/2015
System a amino acid transport-targeted brain and systemic tumor PET imaging agents 2-amino-3-[(18)F]fluoro-2-methylpropanoic acid and 3-[(18)F]fluoro-2-methyl-2-(methylamino)propanoic acid. Nuclear medicine and biology	W Yu, J McConathy, JJ Olson, MM Goodman	01/01/2015
PET imaging of bacterial infections with fluorine-18-labeled maltohexaose. Angewandte Chemie (International ed. in English)	X Ning, W Seo, S Lee, K Takemiya, M Rafi, X Feng, D Weiss, X Wang, L Williams, VM Camp, M Eugene, WR Taylor, M Goodman, N Murthy	12/15/2014
Anti-1-amino-3-18F-fluorocyclobutane-1-carboxylic acid: physiologic uptake patterns, incidental findings, and variants that may simulate disease. Journal of nuclear medicine : official publication, Society of Nuclear Medicine	DM Schuster, C Nanni, S Fanti, S Oka, H Okudaira, Y Inoue, J Sörensen, R Owenius, P Choyke, B Turkbey, TV Bogsrud, T Bach-Gansmo, RK Halkar, JA Nye, OA Odewole, B Savir-Baruch, MM Goodman	12/01/2014
Biochemical and biophysical investigation of the brain-derived neurotrophic factor mimetic 7,8-dihydroxyflavone in the binding and activation of the TrkB receptor. The Journal of biological chemistry	X Liu, O Obianyo, CB Chan, J Huang, S Xue, JJ Yang, F Zeng, M Goodman, K Ye	10/03/2014
Neuroanatomical distribution of oxytocin and vasopressin 1a receptors in the socially monogamous coppery titi monkey (Callicebus cupreus). Neuroscience	SM Freeman, H Walum, K Inoue, AL Smith, MM Goodman, KL Bales, LJ Young	07/25/2014
The neuroanatomical distribution of oxytocin receptor binding and mRNA in the male rhesus macaque (Macaca mulatta). Psychoneuroendocrinology	SM Freeman, K Inoue, AL Smith, MM Goodman, LJ Young	07/01/2014
A thermostable bacterial cocaine esterase rapidly eliminates cocaine from brain in nonhuman primates. Translational psychiatry	LL Howell, JA Nye, JS Stehouwer, RJ Voll, J Mun, D Narasimhan, J Nichols, R Sunahara, MM Goodman, FI Carroll, JH Woods	07/01/2014
Differences in transport mechanisms of trans-1-amino-3-[18F]fluorocyclobutanecarboxylic acid in inflammation, prostate cancer, and glioma cells: comparison with L-[methyl-11C]methionine and 2-deoxy-2-[18F]fluoro-D-glucose. Molecular imaging and biology	S Oka, H Okudaira, M Ono, DM Schuster, MM Goodman, K Kawai, Y Shirakami	06/01/2014
Anti-3-[(18)F]FACBC positron emission tomography-computerized tomography and (111)In-capromab pendetide single photon emission computerized tomography-computerized tomography for recurrent prostate carcinoma: results of a prospective clinical trial. The Journal of urology	DM Schuster, PT Nieh, AB Jani, R Amzat, FD Bowman, RK Halkar, VA Master, JA Nye, OA Odewole, AO Osunkoya, B Savir-Baruch, P Alaei-Taleghani, MM Goodman	05/01/2014
Quantification of dopamine transporter density with [18F]FECNT PET in healthy humans. Nuclear medicine and biology	JA Nye, JR Votaw, JD Bremner, MR Davis, RJ Voll, VM Camp, MM Goodman	03/01/2014
Oestradiol alters central 5-HT1A receptor binding potential differences related to psychosocial stress but not differences related to 5-HTTLPR genotype in female rhesus monkeys. Journal of neuroendocrinology	V Michopoulos, M Perez Diaz, M Embree, K Reding, JR Votaw, J Mun, RJ Voll, MM Goodman, M Wilson, M Sanchez, D Toufexis	02/01/2014
Awareness of and attitudes towards infertility and its treatment: a cross-sectional survey of men in a United States primary care population. Asian journal of andrology	RS Gerhard, CW Ritenour, M Goodman, D Vashi, W Hsiao	01/01/2014
CRH receptor antagonism reverses the effect of social subordination upon central GABAA receptor binding in estradiol-treated ovariectomized female rhesus monkeys. Neuroscience	V Michopoulos, M Embree, K Reding, MM Sanchez, D Toufexis, JR Votaw, RJ Voll, MM Goodman, J Rivier, ME Wilson, SL Berga	10/10/2013
Investigation of an F-18 oxytocin receptor selective ligand via PET imaging. Bioorganic & medicinal chemistry letters	AL Smith, SM Freeman, RJ Voll, LJ Young, MM Goodman	10/01/2013
Decreased brainstem and putamen SERT binding potential in depressed suicide attempters using [11C]-zient PET imaging. Depression and anxiety	JA Nye, D Purselle, C Plisson, RJ Voll, JS Stehouwer, JR Votaw, CD Kilts, MM Goodman, CB Nemeroff	10/01/2013
Pilot study of the utility of the synthetic PET amino-acid radiotracer anti-1-amino-3-[(18)F]fluorocyclobutane-1-carboxylic acid for the noninvasive imaging of pulmonary lesions. Molecular imaging and biology	R Amzat, P Taleghani, DL Miller, JJ Beitler, LM Bellamy, JA Nye, W Yu, B Savir-Baruch, AO Osunkoya, Z Chen, WF Auffermann, MM Goodman, DM Schuster	10/01/2013
Chronic interferon-α decreases dopamine 2 receptor binding and striatal dopamine release in association with anhedonia-like behavior in nonhuman primates. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology	JC Felger, J Mun, HL Kimmel, JA Nye, DF Drake, CR Hernandez, AA Freeman, DB Rye, MM Goodman, LL Howell, AH Miller	10/01/2013
Synthesis of a phenolic precursor and its efficient O-[18F]fluoroethylation with purified no-carrier-added [18F]2-fluoroethyl brosylate as the labeling agent. Journal of labelled compounds & radiopharmaceuticals	N Jarkas, RJ Voll, MM Goodman	09/01/2013
Kinetic analyses of trans-1-amino-3-[18F]fluorocyclobutanecarboxylic acid transport in Xenopus laevis oocytes expressing human ASCT2 and SNAT2. Nuclear medicine and biology	H Okudaira, T Nakanishi, S Oka, M Kobayashi, H Tamagami, DM Schuster, MM Goodman, Y Shirakami, I Tamai, K Kawai	07/01/2013
An improved synthesis of [11C]MENET via Suzuki coupling with [11C]methyl iodide. Journal of labelled compounds & radiopharmaceuticals	F Zeng, RJ Voll, RJ Crowe, MS Waldrep, KB Dolph, MM Goodman	05/15/2013
Carbon-11 N-methyl alkylation of L-368,899 and in vivo PET imaging investigations for neural oxytocin receptors. Bioorganic & medicinal chemistry letters	AL Smith, SM Freeman, RJ Voll, LJ Young, MM Goodman	02/01/2013
The relation of developmental changes in brain serotonin transporter (5HTT) and 5HT1A receptor binding to emotional behavior in female rhesus monkeys: effects of social status and 5HTT genotype. Neuroscience	M Embree, V Michopoulos, JR Votaw, RJ Voll, J Mun, JS Stehouwer, MM Goodman, ME Wilson, MM Sánchez	01/03/2013
Characterization of primary prostate carcinoma by anti-1-amino-2-[(18)F] -fluorocyclobutane-1-carboxylic acid (anti-3-[(18)F] FACBC) uptake. American journal of nuclear medicine and molecular imaging	DM Schuster, PA Taleghani, PT Nieh, VA Master, R Amzat, B Savir-Baruch, RK Halkar, T Fox, AO Osunkoya, CS Moreno, JA Nye, W Yu, B Fei, Z Wang, Z Chen, MM Goodman	01/01/2013
Fluorine-18 radiolabeled heterocycles as PET tracers for imaging β-amyloid plaques in Alzheimer's disease. Current topics in medicinal chemistry	F Zeng, MM Goodman	01/01/2013
Fluorine-containing drugs as PET diagnostics (F-18 labeled tracers). Current topics in medicinal chemistry	MM Goodman, J McConathy	01/01/2013
(11) C and (18) F PET radioligands for the serotonin transporter (SERT). Journal of labelled compounds & radiopharmaceuticals	JS Stehouwer, MM Goodman	01/01/2013
Arylsulfonamide KCN1 inhibits in vivo glioma growth and interferes with HIF signaling by disrupting HIF-1α interaction with cofactors p300/CBP. Clinical cancer research : an official journal of the American Association for Cancer Research	S Yin, S Kaluz, NS Devi, AA Jabbar, RG de Noronha, J Mun, Z Zhang, PR Boreddy, W Wang, Z Wang, T Abbruscato, Z Chen, JJ Olson, R Zhang, MM Goodman, KC Nicolaou, EG Van Meir	12/15/2012
Binding Model for the Interaction of Anticancer Arylsulfonamides with the p300 Transcription Cofactor. ACS medicinal chemistry letters	Q Shi, S Yin, S Kaluz, N Ni, NS Devi, J Mun, D Wang, K Damera, W Chen, S Burroughs, SR Mooring, MM Goodman, EG Van Meir, B Wang, JP Snyder	08/09/2012
Design and in vitro activities of N-alkyl-N-[(8-R-2,2-dimethyl-2H-chromen-6-yl)methyl]heteroarylsulfonamides, novel, small-molecule hypoxia inducible factor-1 pathway inhibitors and anticancer agents. Journal of medicinal chemistry	J Mun, AA Jabbar, NS Devi, S Yin, Y Wang, C Tan, D Culver, JP Snyder, EG Van Meir, MM Goodman	08/09/2012
Neurobiological changes mediating the effects of chronic fluoxetine on cocaine use. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology	EK Sawyer, J Mun, JA Nye, HL Kimmel, RJ Voll, JS Stehouwer, KC Rice, MM Goodman, LL Howell	07/01/2012
Simultaneous measurement of extracellular dopamine and dopamine transporter occupancy by cocaine analogs in squirrel monkeys. Synapse (New York, N.Y.)	HL Kimmel, JA Nye, R Voll, J Mun, J Stehouwer, MM Goodman, JR Votaw, FI Carroll, LL Howell	06/01/2012
Synthesis and evaluation of C-11, F-18 and I-125 small molecule radioligands for detecting oxytocin receptors. Bioorganic & medicinal chemistry	AL Smith, SM Freeman, JS Stehouwer, K Inoue, RJ Voll, LJ Young, MM Goodman	04/15/2012
Transport mechanisms of trans-1-amino-3-fluoro[1-(14)C]cyclobutanecarboxylic acid in prostate cancer cells. Nuclear medicine and biology	S Oka, H Okudaira, Y Yoshida, DM Schuster, MM Goodman, Y Shirakami	01/01/2012
Development of a unique small molecule modulator of CXCR4. PloS one	Z Liang, W Zhan, A Zhu, Y Yoon, S Lin, M Sasaki, JM Klapproth, H Yang, HE Grossniklaus, J Xu, M Rojas, RJ Voll, MM Goodman, RF Arrendale, J Liu, CC Yun, JP Snyder, DC Liotta, H Shim	01/01/2012
Pilot evaluation of anti-1-amino-2-[18F] fluorocyclopentane-1-carboxylic acid (anti-2-[18F] FACPC) PET-CT in recurrent prostate carcinoma. Molecular imaging and biology	B Savir-Baruch, DM Schuster, N Jarkas, VA Master, PT Nieh, RK Halkar, JA Nye, MM Lewis, RJ Crowe, RJ Voll, VM Camp, LM Bellamy, DL Roberts, MM Goodman	12/01/2011
Biodistribution and human dosimetry of enantiomer-1 of the synthetic leucine analog anti-1-amino-2-fluorocyclopentyl-1-carboxylic acid. Nuclear medicine and biology	JA Nye, N Jarkas, DM Schuster, B Savir-Baruch, RJ Voll, VM Camp, MM Goodman	10/01/2011
Unusual presentations of metastatic prostate carcinoma as detected by anti-3 F-18 FACBC PET/CT. Clinical nuclear medicine	R Amzat, P Taleghani, B Savir-Baruch, PT Nieh, VA Master, RK Halkar, MM Lewis, M Faurot, LM Bellamy, MM Goodman, DM Schuster	09/01/2011
Detection of recurrent prostate carcinoma with anti-1-amino-3-18F-fluorocyclobutane-1-carboxylic acid PET/CT and 111In-capromab pendetide SPECT/CT. Radiology	DM Schuster, B Savir-Baruch, PT Nieh, VA Master, RK Halkar, PJ Rossi, MM Lewis, JA Nye, W Yu, FD Bowman, MM Goodman	06/01/2011
(18)F-FECNT: validation as PET dopamine transporter ligand in parkinsonism. Experimental neurology	G Masilamoni, J Votaw, L Howell, RM Villalba, M Goodman, RJ Voll, J Stehouwer, T Wichmann, Y Smith	12/01/2010
(R,S)-anti-1-amino-2-[18F]fluorocyclopentyl-1-carboxylic acid: synthesis from racemic 2-benzyloxycyclopentanone and biological evaluation for brain tumor imaging with positron emission tomography. Journal of medicinal chemistry	N Jarkas, RJ Voll, L Williams, VM Camp, MM Goodman	09/23/2010
Synthesis, fluorine-18 radiolabeling, and biological evaluation of N-((E)-4-fluorobut-2-en-1-yl)-2beta-carbomethoxy-3beta-(4'-halophenyl)nortropanes: candidate radioligands for in vivo imaging of the brain dopamine transporter with positron emission tomography. Journal of medicinal chemistry	JS Stehouwer, LM Daniel, P Chen, RJ Voll, L Williams, SJ Plott, JR Votaw, MJ Owens, L Howell, MM Goodman	08/12/2010
Validation of two fluoro-analogues of N,N-dimethyl-2-(2'-amino-4'-hydroxymethyl-phenylthio)benzylamine as serotonin transporter imaging agents using microPET. Nuclear medicine and biology	N Jarkas, RJ Voll, L Williams, MM Goodman	07/01/2010
Synthesis and biological evaluation of anti-1-amino-2-[18F]fluoro-cyclobutyl-1-carboxylic acid (anti-2-[18F]FACBC) in rat 9L gliosarcoma. Bioorganic & medicinal chemistry letters	W Yu, L Williams, VM Camp, JJ Olson, MM Goodman	04/01/2010
Cortical activation during cocaine use and extinction in rhesus monkeys. Psychopharmacology	LL Howell, JR Votaw, MM Goodman, KP Lindsey	02/01/2010
Synthesis, radiolabeling, and biological evaluation of (R)- and (S)-2-amino-3-[(18)F]fluoro-2-methylpropanoic acid (FAMP) and (R)- and (S)-3-[(18)F]fluoro-2-methyl-2-N-(methylamino)propanoic acid (NMeFAMP) as potential PET radioligands for imaging brain tumors. Journal of medicinal chemistry	W Yu, J McConathy, L Williams, VM Camp, EJ Malveaux, Z Zhang, JJ Olson, MM Goodman	01/28/2010
Role of dopamine transporters in the behavioral effects of 3,4-methylenedioxymethamphetamine (MDMA) in nonhuman primates. Psychopharmacology	WE Fantegrossi, RM Bauzo, DM Manvich, JC Morales, JR Votaw, MM Goodman, LL Howell	08/01/2009
Stereoselective synthesis and biological evaluation of syn-1-amino-3-[18F]fluorocyclobutyl-1-carboxylic acid as a potential positron emission tomography brain tumor imaging agent. Bioorganic & medicinal chemistry	W Yu, L Williams, VM Camp, E Malveaux, JJ Olson, MM Goodman	03/01/2009
Synthesis, radiosynthesis, and biological evaluation of carbon-11 and fluorine-18 labeled reboxetine analogues: potential positron emission tomography radioligands for in vivo imaging of the norepinephrine transporter. Journal of medicinal chemistry	F Zeng, J Mun, N Jarkas, JS Stehouwer, RJ Voll, GD Tamagnan, L Howell, JR Votaw, CD Kilts, CB Nemeroff, MM Goodman	01/08/2009
Initial experience with the radiotracer anti-1-amino-3-[18F]Fluorocyclobutane-1-carboxylic acid (anti-[ 18F]FACBC) with PET in renal carcinoma. Molecular imaging and biology	DM Schuster, JA Nye, PT Nieh, JR Votaw, RK Halkar, MM Issa, W Yu, J Sepulveda, W Zeng, A Young, MM Goodman	01/01/2009
Fluorine-18 Radiolabeled PET Tracers for Imaging Monoamine Transporters: Dopamine, Serotonin, and Norepinephrine. PET clinics	JS Stehouwer, MM Goodman	01/01/2009
Synthesis, radiosynthesis, and biological evaluation of fluorine-18-labeled 2beta-carbo(fluoroalkoxy)-3beta-(3'-((Z)-2-haloethenyl)phenyl)nortropanes: candidate radioligands for in vivo imaging of the serotonin transporter with positron emission tomography. Journal of medicinal chemistry	JS Stehouwer, N Jarkas, F Zeng, RJ Voll, L Williams, VM Camp, EJ Malveaux, JR Votaw, L Howell, MJ Owens, MM Goodman	12/25/2008
Compartmental modeling of 11C-HOMADAM binding to the serotonin transporter in the healthy human brain. Journal of nuclear medicine : official publication, Society of Nuclear Medicine	JA Nye, JR Votaw, N Jarkas, D Purselle, V Camp, JD Bremner, CD Kilts, CB Nemeroff, MM Goodman	12/01/2008
Relationship between rate of drug uptake in brain and behavioral pharmacology of monoamine transporter inhibitors in rhesus monkeys. Pharmacology, biochemistry, and behavior	HL Kimmel, SS Negus, KM Wilcox, SB Ewing, J Stehouwer, MM Goodman, JR Votaw, NK Mello, FI Carroll, LL Howell	09/01/2008
Syntheses and biological activities of novel 2-methoxyestradiol analogs, 2-fluoroethoxyestradiol and 2-fluoropropanoxyestradiol, and a radiosynthesis of 2-[(18)F]fluoroethoxyestradiol for positron emission tomography. Nuclear medicine and biology	J Mun, Y Wang, RJ Voll, D Escuin-Borras, P Giannakakou, MM Goodman	07/01/2008
Synthesis and evaluation of [123I] labeled iodovinyl amino acids syn-, anti-1-amino-3-[2-iodoethenyl]-cyclobutane-1-carboxylic acid, and 1-amino-3-iodomethylene-cyclobutane-1-carboxylic acid as potential SPECT brain tumor imaging agents. Bioorganic & medicinal chemistry letters	W Yu, L Williams, E Malveaux, VM Camp, JJ Olson, MM Goodman	02/15/2008
Synthesis and in vivo evaluation of halogenated N,N-dimethyl-2-(2'-amino-4'-hydroxymethylphenylthio)benzylamine derivatives as PET serotonin transporter ligands. Journal of medicinal chemistry	N Jarkas, RJ Voll, L Williams, JR Votaw, M Owens, MM Goodman	01/24/2008
Synthesis, in vitro characterization, and radiolabeling of reboxetine analogs as potential PET radioligands for imaging the norepinephrine transporter. Bioorganic & medicinal chemistry	F Zeng, N Jarkas, JS Stehouwer, RJ Voll, MJ Owens, CD Kilts, CB Nemeroff, MM Goodman	01/15/2008