Nicolas T. Seyfried, PhD
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Research Program
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Phone Number
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Email Address
Nicholas Seyfried, PhD, is a professor in the Department of Biochemistry and Neurology at Emory University School of Medicine and is a member of the Center for Neurodegenerative Diseases. As scientific director of the Emory Integrated Proteomics Core, he coordinates efforts to address the needs of investigators needing protein analytical services by cutting edge mass spectrometry.
Dr. Seyfried earned his PhD in Biochemistry from the University of Oxford. He completed a postdoctoral fellowship at Emory University School of Medicine and held a postdoctoral research position in the Complex Carbohydrate Research Center at the University of Georgia.
Dr. Seyfried holds memberships with American Society for Mass Spectrometry, Society for Neuroscience and American Society for Neurochemistry.
Dr. Seyfried's research is focused on the use of quantitative proteomics to identify and characterize disease-specific proteins and their post-translational modifications (PTMs) in neurodegeneration.
Grant Number | Title |
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5R01AG061800-05 | Identifying therapeutic targets that confer synaptic resilience to Alzheimer's disease |
Title/Journal | Authors | Publication Date |
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Epigenetics |
F Grodstein, B Lemos, J Yang, K de Paiva Lopes, RA Vialle, N Seyfried, Y Wang, G Shireby, E Hannon, A Thomas, K Brookes, J Mill, PL De Jager, DA Bennett | 12/01/2024 |
Alzheimer's & dementia : the journal of the Alzheimer's Association |
JS Reddy, L Heath, AV Linden, M Allen, KP Lopes, F Seifar, E Wang, Y Ma, WL Poehlman, ZS Quicksall, A Runnels, Y Wang, DM Duong, L Yin, K Xu, ES Modeste, A Shantaraman, EB Dammer, L Ping, SR Oatman, J Scanlan, C Ho, MM Carrasquillo, M Atik, G Yepez, AO Mitchell, TT Nguyen, X Chen, DX Marquez, H Reddy, H Xiao, S Seshadri, R Mayeux, S Prokop, EB Lee, GE Serrano, TG Beach, AF Teich, V Haroutunian, EJ Fox, M Gearing, A Wingo, T Wingo, JJ Lah, AI Levey, DW Dickson, LL Barnes, P De Jager, B Zhang, D Bennett, NT Seyfried, AK Greenwood, N Ertekin-Taner | 08/30/2024 |
The journals of gerontology. Series A, Biological sciences and medical sciences |
A Nagarajan, J Laird, O Ugochukwu, S Reppe, K Gautvik, RD Ross, DA Bennett, C Rosen, DP Kiel, LA Higginbotham, NT Seyfried, CW Lary | 08/28/2024 |
Alzheimer's & dementia : the journal of the Alzheimer's Association |
BN Lizama, C Williams, HA North, K Pandey, D Duong, V Di Caro, AP Mecca, K Blennow, H Zetterberg, AI Levey, M Grundman, CH van Dyck, AO Caggiano, NT Seyfried, ME Hamby | 08/21/2024 |
Nature aging |
EA Frick, V Emilsson, T Jonmundsson, AE Steindorsdottir, ECB Johnson, R Puerta, EB Dammer, A Shantaraman, A Cano, M Boada, S Valero, P García-González, EF Gudmundsson, A Gudjonsson, R Pitts, X Qiu, N Finkel, JJ Loureiro, AP Orth, NT Seyfried, AI Levey, A Ruiz, T Aspelund, LL Jennings, LJ Launer, V Gudmundsdottir, V Gudnason | 08/21/2024 |
Human molecular genetics |
M Pavešković, RB De-Paula, SA Ojelade, EK Tantry, MY Kochukov, S Bao, S Veeraragavan, AR Garza, S Srivastava, SY Song, M Fujita, DM Duong, DA Bennett, PL De Jager, NT Seyfried, ME Dickinson, JD Heaney, BR Arenkiel, JM Shulman | 08/16/2024 |
Dendritic spine head diameter predicts episodic memory performance in older adults. Science advances |
CK Walker, E Liu, KM Greathouse, AB Adamson, JP Wilson, EH Poovey, KA Curtis, HM Muhammad, AJ Weber, DA Bennett, NT Seyfried, C Gaiteri, JH Herskowitz | 08/09/2024 |
bioRxiv : the preprint server for biology |
AM Goettemoeller, E Banks, P Kumar, VJ Olah, KE McCann, K South, CC Ramelow, A Eaton, DM Duong, NT Seyfried, D Weinshenker, S Rangaraju, MJ Rowan | 07/05/2024 |
Psychosocial experiences are associated with human brain mitochondrial biology. Proceedings of the National Academy of Sciences of the United States of America |
C Trumpff, AS Monzel, C Sandi, V Menon, HU Klein, M Fujita, A Lee, VA Petyuk, C Hurst, DM Duong, NT Seyfried, AP Wingo, TS Wingo, Y Wang, M Thambisetty, L Ferrucci, DA Bennett, PL De Jager, M Picard | 07/02/2024 |
Proteins linking APOE ɛ4 with Alzheimer's disease. Alzheimer's & dementia : the journal of the Alzheimer's Association |
S Oveisgharan, L Yu, K de Paiva Lopes, S Tasaki, Y Wang, V Menon, JA Schneider, NT Seyfried, DA Bennett | 07/01/2024 |
Science translational medicine |
EB Dammer, A Shantaraman, L Ping, DM Duong, ES Gerasimov, SP Ravindran, V Gudmundsdottir, EA Frick, GT Gomez, KA Walker, V Emilsson, LL Jennings, V Gudnason, D Western, C Cruchaga, JJ Lah, TS Wingo, AP Wingo, NT Seyfried, AI Levey, ECB Johnson | 06/26/2024 |
Alzheimer's & dementia : the journal of the Alzheimer's Association |
AM Wojtas, EB Dammer, Q Guo, L Ping, A Shantaraman, DM Duong, L Yin, EJ Fox, F Seifar, EB Lee, ECB Johnson, JJ Lah, AI Levey, Y Levites, S Rangaraju, TE Golde, NT Seyfried | 06/01/2024 |
Molecular neurobiology |
Z Mei, J Liu, JP Schroeder, D Weinshenker, DM Duong, NT Seyfried, Y Li, P Jin, AP Wingo, TS Wingo | 06/01/2024 |
Systems biology dissection of PTSD and MDD across brain regions, cell types, and blood. Science (New York, N.Y.) |
NP Daskalakis, A Iatrou, C Chatzinakos, A Jajoo, C Snijders, D Wylie, CP DiPietro, I Tsatsani, CY Chen, CD Pernia, M Soliva-Estruch, D Arasappan, RA Bharadwaj, L Collado-Torres, S Wuchty, VE Alvarez, EB Dammer, A Deep-Soboslay, DM Duong, N Eagles, BR Huber, L Huuki, VL Holstein, MW Logue, JF Lugenbühl, AX Maihofer, MW Miller, CM Nievergelt, G Pertea, D Ross, MSE Sendi, BB Sun, R Tao, J Tooke, EJ Wolf, Z Zeier, S Berretta, FA Champagne, T Hyde, NT Seyfried, JH Shin, DR Weinberger, CB Nemeroff, JE Kleinman, KJ Ressler | 05/24/2024 |
Nature biotechnology |
B Aguzzoli Heberle, JA Brandon, ML Page, KA Nations, KI Dikobe, BJ White, LA Gordon, GA Fox, ME Wadsworth, PH Doyle, BA Williams, EJ Fox, A Shantaraman, M Ryten, S Goodwin, E Ghiban, R Wappel, S Mavruk-Eskipehlivan, JB Miller, NT Seyfried, PT Nelson, JD Fryer, MTW Ebbert | 05/22/2024 |
Biochemical and neurophysiological effects of deficiency of the mitochondrial import protein TIMM50. bioRxiv : the preprint server for biology |
E Paz, S Jain, I Gottfried, O Staretz-Chacham, M Mahajnah, P Bagchi, NT Seyfried, U Ashery, A Azem | 05/20/2024 |
Associations of brain morphology with cortical proteins of cognitive resilience. Neurobiology of aging |
VN Poole, AR Ridwan, K Arfanakis, RJ Dawe, NT Seyfried, PL De Jager, JA Schneider, SE Leurgans, L Yu, DA Bennett | 05/01/2024 |
bioRxiv : the preprint server for biology |
H Huhe, SM Shapley, D Duong, F Wu, SK Ha, SH Choi, J Kofler, Y Mou, TR Guimaraes, A Thathiah, LKH Schaeffer, GW Carter, NT Seyfried, AC Silva, SJ Sukoff Rizzo | 04/29/2024 |
Large-scale Deep Proteomic Analysis in Alzheimer's Disease Brain Regions Across Race and Ethnicity. bioRxiv : the preprint server for biology |
F Seifar, EJ Fox, A Shantaraman, Y Liu, EB Dammer, E Modeste, DM Duong, L Yin, AN Trautwig, Q Guo, K Xu, L Ping, JS Reddy, M Allen, Z Quicksall, L Heath, J Scanlan, E Wang, M Wang, AV Linden, W Poehlman, X Chen, S Baheti, C Ho, T Nguyen, G Yepez, AO Mitchell, SR Oatman, X Wang, MM Carrasquillo, A Runnels, T Beach, GE Serrano, DW Dickson, EB Lee, TE Golde, S Prokop, LL Barnes, B Zhang, V Haroutunian, M Gearing, JJ Lah, P Jager, DA Bennett, A Greenwood, N Ertekin-Taner, AI Levey, A Wingo, T Wingo, NT Seyfried | 04/26/2024 |
bioRxiv : the preprint server for biology |
JS Reddy, L Heath, A Vander Linden, M Allen, K de Paiva Lopes, F Seifar, E Wang, Y Ma, WL Poehlman, ZS Quicksall, A Runnels, Y Wang, DM Duong, L Yin, K Xu, ES Modeste, A Shantaraman, EB Dammer, L Ping, SR Oatman, J Scanlan, C Ho, MM Carrasquillo, M Atik, G Yepez, AO Mitchell, TT Nguyen, X Chen, DX Marquez, H Reddy, H Xiao, S Seshadri, R Mayeux, S Prokop, EB Lee, GE Serrano, TG Beach, AF Teich, V Haroutunian, EJ Fox, M Gearing, A Wingo, T Wingo, JJ Lah, AI Levey, DW Dickson, LL Barnes, P De Jager, B Zhang, D Bennett, NT Seyfried, AK Greenwood, N Ertekin-Taner | 04/20/2024 |
Neurology |
AS Buchman, L Yu, HU Klein, AR Zammit, S Oveisgharan, S Nag, N Tickotsky, H Levy, N Seyfried, D Morgenstern, Y Levin, M Schnaider Beeri, DA Bennett | 04/09/2024 |
Person-specific differences in ubiquitin-proteasome mediated proteostasis in human neurons. Alzheimer's & dementia : the journal of the Alzheimer's Association |
YC Hsieh, ZM Augur, M Arbery, N Ashour, K Barrett, RV Pearse, ES Tio, DM Duong, D Felsky, PL De Jager, DA Bennett, NT Seyfried, TL Young-Pearse | 04/01/2024 |
Nature communications |
P Kumar, AM Goettemoeller, C Espinosa-Garcia, BR Tobin, A Tfaily, RS Nelson, A Natu, EB Dammer, JV Santiago, S Malepati, L Cheng, H Xiao, DD Duong, NT Seyfried, LB Wood, MJM Rowan, S Rangaraju | 04/01/2024 |
Research square |
R Saloner, A Staffaroni, E Dammer, ECB Johnson, E Paolillo, A Wise, H Heuer, L Forsberg, AL Lago, J Webb, J Vogel, A Santillo, O Hansson, J Kramer, B Miller, J Li, J Loureiro, R Sivasankaran, K Worringer, N Seyfried, J Yokoyama, W Seeley, S Spina, L Grinberg, L VandeVrede, P Ljubenkov, E Bayram, A Bozoki, D Brushaber, C Considine, G Day, B Dickerson, K Domoto-Reilly, K Faber, D Galasko, D Geschwind, N Ghoshal, N Graff-Radford, C Hales, L Honig, GY Hsiung, E Huey, J Kornak, W Kremers, M Lapid, S Lee, I Litvan, C McMillan, M Mendez, T Miyagawa, A Pantelyat, B Pascual, H Paulson, L Petrucelli, P Pressman, E Ramos, K Rascovsky, E Roberson, R Savica, A Snyder, AC Sullivan, C Tartaglia, M Vandebergh, B Boeve, H Rosen, J Rojas, A Boxer, K Casaletto | 03/28/2024 |
Research square |
E Ortlund, CY Chen, K Maner-Smith, M Khadka, J Ahn, X Gulbin, A Ivanova, E Dammer, N Seyfried, D Bennett, I Hajjar | 02/27/2024 |
Heparin-enriched plasma proteome is significantly altered in Alzheimer's Disease. Research square |
Q Guo, L Ping, EB Dammer, L Yin, K Xu, A Shantaraman, EJ Fox, TE Golde, ECB Johnson, BR Roberts, JJ Lah, AI Levey, NT Seyfried | 02/23/2024 |
Mis-spliced transcripts generate de novo proteins in TDP-43-related ALS/FTD. Science translational medicine |
S Seddighi, YA Qi, AL Brown, OG Wilkins, C Bereda, C Belair, YJ Zhang, M Prudencio, MJ Keuss, A Khandeshi, S Pickles, SE Kargbo-Hill, J Hawrot, DM Ramos, H Yuan, J Roberts, EK Sacramento, SI Shah, MA Nalls, JM Colón-Mercado, JF Reyes, VH Ryan, MP Nelson, CN Cook, Z Li, L Screven, JY Kwan, PR Mehta, M Zanovello, M Hallegger, A Shantaraman, L Ping, Y Koike, B Oskarsson, NP Staff, DM Duong, A Ahmed, M Secrier, J Ule, S Jacobson, DS Reich, JD Rohrer, A Malaspina, DW Dickson, JD Glass, A Ori, NT Seyfried, M Maragkakis, L Petrucelli, P Fratta, ME Ward | 02/14/2024 |
Cryptic exon inclusion is a molecular signature of LATE-NC in aging brains. Acta neuropathologica |
M Chung, EK Carter, AM Veire, EB Dammer, J Chang, DM Duong, N Raj, GJ Bassell, JD Glass, TF Gendron, PT Nelson, AI Levey, NT Seyfried, ZT McEachin | 02/03/2024 |
bioRxiv : the preprint server for biology |
A Shantaraman, EB Dammer, O Ugochukwu, DM Duong, L Yin, EK Carter, M Gearing, A Chen-Plotkin, EB Lee, JQ Trojanowski, DA Bennett, JJ Lah, AI Levey, NT Seyfried, L Higginbotham | 01/24/2024 |
Science translational medicine |
JD Marks, VE Ayuso, Y Carlomagno, M Yue, TW Todd, Y Hao, Z Li, ZT McEachin, A Shantaraman, DM Duong, LM Daughrity, K Jansen-West, W Shao, A Calliari, JG Bejarano, M DeTure, B Rawlinson, MC Casey, MT Lilley, MH Donahue, VM Jawahar, BF Boeve, RC Petersen, DS Knopman, B Oskarsson, NR Graff-Radford, ZK Wszolek, DW Dickson, KA Josephs, YA Qi, NT Seyfried, ME Ward, YJ Zhang, M Prudencio, L Petrucelli, CN Cook | 01/17/2024 |
medRxiv : the preprint server for health sciences |
Y Shen, M Ali, J Timsina, C Wang, A Do, D Western, M Liu, P Gorijala, J Budde, H Liu, B Gordon, E McDade, JC Morris, JJ Llibre-Guerra, RJ Bateman, N Joseph-Mathurin, RJ Perrin, D Maschi, T Wyss-Coray, P Pastor, A Goate, AE Renton, EI Surace, ECB Johnson, AI Levey, I Alvarez, J Levin, JM Ringman, RF Allegri, N Seyfried, GS Day, Q Wu, MV Fernández, L Ibanez, YJ Sung, C Cruchaga | 01/13/2024 |
medRxiv : the preprint server for health sciences |
AM Wojtas, EB Dammer, Q Guo, L Ping, A Shantaraman, DM Duong, L Yin, EJ Fox, F Seifar, EB Lee, ECB Johnson, JJ Lah, AI Levey, Y Levites, S Rangaraju, TE Golde, NT Seyfried | 01/11/2024 |
OXR1 maintains the retromer to delay brain aging under dietary restriction. Nature communications |
KA Wilson, S Bar, EB Dammer, EM Carrera, BA Hodge, TAU Hilsabeck, J Bons, GW Brownridge, JN Beck, J Rose, M Granath-Panelo, CS Nelson, G Qi, AA Gerencser, J Lan, A Afenjar, G Chawla, RB Brem, PM Campeau, HJ Bellen, B Schilling, NT Seyfried, LM Ellerby, P Kapahi | 01/11/2024 |
Neurology |
AR Zammit, HU Klein, L Yu, AI Levey, NT Seyfried, AP Wingo, TS Wingo, JA Schneider, DA Bennett, AS Buchman | 01/09/2024 |
Serum proteomics reveals APOE dependent and independent protein signatures in Alzheimer's disease. Research square |
V Gudmundsdottir, E Frick, V Emilsson, T Jonmundsson, A Steindorsdottir, ECB Johnson, R Puerta, E Dammer, A Shantaraman, A Cano, M Boada, S Valero, P Garcia-Gonzalez, E Gudmundsson, A Gudjonsson, R Pitts, X Qiu, N Finkel, J Loureiro, A Orth, N Seyfried, A Levey, A Ruiz, T Aspelund, L Jennings, L Launer, V Gudnason | 01/09/2024 |
Proteomic Signaling of Dual-Specificity Phosphatase 4 (DUSP4) in Alzheimer's Disease. Biomolecules |
E Wang, AL Pan, P Bagchi, S Rangaraju, NT Seyfried, ME Ehrlich, SR Salton, B Zhang | 01/03/2024 |
Associations of cortical SPP1 and ITGAX with cognition and common neuropathologies in older adults. Alzheimer's & dementia : the journal of the Alzheimer's Association |
KP Lopes, L Yu, X Shen, Y Qiu, S Tasaki, A Iatrou, MS Beeri, NT Seyfried, V Menon, Y Wang, JA Schneider, H Cantor, DA Bennett | 01/01/2024 |
bioRxiv : the preprint server for biology |
BA Heberle, JA Brandon, ML Page, KA Nations, KI Dikobe, BJ White, LA Gordon, GA Fox, ME Wadsworth, PH Doyle, BA Williams, EJ Fox, A Shantaraman, M Ryten, S Goodwin, E Ghiban, R Wappel, S Mavruk-Eskipehlivan, JB Miller, NT Seyfried, PT Nelson, JD Fryer, MTW Ebbert | 12/11/2023 |
Aβ Amyloid Scaffolds the Accumulation of Matrisome and Additional Proteins in Alzheimer's Disease. bioRxiv : the preprint server for biology |
Y Levites, EB Dammer, Y Ran, W Tsering, D Duong, M Abreha, J Gadhavi, K Lolo, J Trejo-Lopez, JL Phillips, A Iturbe, A Erqiuzi, BD Moore, D Ryu, A Natu, KD Dillon, J Torrellas, C Moran, TB Ladd, KF Afroz, T Islam, J Jagirdar, CC Funk, M Robinson, DR Borchelt, N Ertekin-Taner, JW Kelly, FL Heppner, EC Johnson, K McFarland, AL Levey, S Prokop, NT Seyfried, TE Golde | 12/07/2023 |
Molecular & cellular proteomics : MCP |
JV Santiago, A Natu, CC Ramelow, S Rayaprolu, H Xiao, V Kumar, P Kumar, NT Seyfried, S Rangaraju | 12/01/2023 |
INPP5D regulates inflammasome activation in human microglia. Nature communications |
V Chou, RV Pearse, AJ Aylward, N Ashour, M Taga, G Terzioglu, M Fujita, SB Fancher, A Sigalov, CR Benoit, H Lee, M Lam, NT Seyfried, DA Bennett, PL De Jager, V Menon, TL Young-Pearse | 11/29/2023 |
Serum proteomics reveals APOE dependent and independent protein signatures in Alzheimer's disease. medRxiv : the preprint server for health sciences |
EA Frick, V Emilsson, T Jonmundsson, AE Steindorsdottir, ECB Johnson, R Puerta, EB Dammer, A Shantaraman, A Cano, M Boada, S Valero, P García-González, EF Gudmundsson, A Gudjonsson, JJ Loureiro, AP Orth, NT Seyfried, AI Levey, A Ruiz, T Aspelund, LL Jennings, LJ Launer, V Gudmundsdottir, V Gudnason | 11/09/2023 |
Research square |
S Bar, KA Wilson, TAU Hilsabeck, S Alderfer, EB Dammer, JB Burton, S Shah, A Holtz, EM Carrera, JN Beck, JH Chen, G Kauwe, TE Tracy, NT Seyfried, B Schilling, LM Ellerby, P Kapahi | 11/08/2023 |
Research square |
AM Goettemoeller, E Banks, KE McCann, P Kumar, K South, VJ Olah, CC Ramelow, DM Duong, NT Seyfried, S Rangaraju, D Weinshenker, MJ Rowan | 11/06/2023 |
medRxiv : the preprint server for health sciences |
EB Dammer, A Shantaraman, L Ping, DM Duong, ES Gerasimov, SP Ravindran, V Gudmundsdottir, EA Frick, GT Gomez, KA Walker, V Emilsson, LL Jennings, V Gudnason, D Western, C Cruchaga, JJ Lah, TS Wingo, AP Wingo, NT Seyfried, AI Levey, ECB Johnson | 10/30/2023 |
Proteomic signaling of dual specificity phosphatase 4 (DUSP4) in Alzheimer's disease. Research square |
E Wang, AL Pan, P Bagchi, S Ranjaraju, NT Seyfried, ME Ehrlich, SR Salton, B Zhang | 10/19/2023 |
Neurobiology of disease |
L Higginbotham, EK Carter, EB Dammer, RU Haque, ECB Johnson, DM Duong, L Yin, PL De Jager, DA Bennett, D Felsky, ES Tio, JJ Lah, AI Levey, NT Seyfried | 10/01/2023 |
Proteomic signaling of dual specificity phosphatase 4 (DUSP4) in Alzheimer's disease. bioRxiv : the preprint server for biology |
E Wang, AL Pan, P Bagchi, S Ranjaraju, NT Seyfried, ME Ehrlich, SR Salton, B Zhang | 09/14/2023 |
Science translational medicine |
R Haque, CM Watson, J Liu, EK Carter, DM Duong, JJ Lah, AP Wingo, BR Roberts, ECB Johnson, AJ Saykin, LM Shaw, NT Seyfried, TS Wingo, AI Levey | 09/06/2023 |
Sex differences in brain protein expression and disease. Nature medicine |
AP Wingo, Y Liu, ES Gerasimov, SM Vattathil, J Liu, DJ Cutler, MP Epstein, GAM Blokland, M Thambisetty, JC Troncoso, DM Duong, DA Bennett, AI Levey, NT Seyfried, TS Wingo | 09/01/2023 |
Cell reports |
H Lee, AJ Aylward, RV Pearse, AM Lish, YC Hsieh, ZM Augur, CR Benoit, V Chou, A Knupp, C Pan, S Goberdhan, DM Duong, NT Seyfried, DA Bennett, MF Taga, K Huynh, M Arnold, PJ Meikle, PL De Jager, V Menon, JE Young, TL Young-Pearse | 08/29/2023 |
Nucleic acids research |
PE Head, P Kapoor-Vazirani, GP Nagaraju, H Zhang, SK Rath, NC Luong, R Haji-Seyed-Javadi, F Sesay, SY Wang, DM Duong, W Daddacha, EV Minten, B Song, D Danelia, X Liu, S Li, EA Ortlund, NT Seyfried, DM Smalley, Y Wang, X Deng, WS Dynan, B El-Rayes, AJ Davis, DS Yu | 08/25/2023 |
Scientific reports |
K Borkowski, NT Seyfried, M Arnold, JJ Lah, AI Levey, CM Hales, EB Dammer, C Blach, G Louie, R Kaddurah-Daouk, JW Newman | 08/23/2023 |
Research square |
Z Mei, J Liu, JP Schroeder, D Weinshenker, DM Duong, NT Seyfried, Y Li, P Jin, AP Wingo, TS Wingo | 08/16/2023 |
Pathogenesis of Alzheimer's disease: Involvement of the choroid plexus. Alzheimer's & dementia : the journal of the Alzheimer's Association |
M Čarna, IG Onyango, S Katina, D Holub, JS Novotny, M Nezvedova, D Jha, Z Nedelska, V Lacovich, TV Vyvere, R Houbrechts, K Garcia-Mansfield, R Sharma, V David-Dirgo, M Vyhnalek, K Texlova, H Chaves, N Bakkar, L Pertierra, M Vinkler, H Markova, J Laczo, K Sheardova, M Hortova-Kohoutkova, J Frič, G Forte, P Kaňovsky, S Belaškova, J Damborsky, J Hort, NT Seyfried, R Bowser, G Sevlever, RA Rissman, RA Smith, M Hajduch, P Pirrotte, Z Spacil, EB Dammer, C Limbäck-Stokin, GB Stokin | 08/01/2023 |
Cerebrospinal fluid proteomics define the natural history of autosomal dominant Alzheimer's disease. Nature medicine |
ECB Johnson, S Bian, RU Haque, EK Carter, CM Watson, BA Gordon, L Ping, DM Duong, MP Epstein, E McDade, NR Barthélemy, CM Karch, C Xiong, C Cruchaga, RJ Perrin, AP Wingo, TS Wingo, JP Chhatwal, GS Day, JM Noble, SB Berman, R Martins, NR Graff-Radford, PR Schofield, T Ikeuchi, H Mori, J Levin, M Farlow, JJ Lah, C Haass, M Jucker, JC Morris, TLS Benzinger, BR Roberts, RJ Bateman, AM Fagan, NT Seyfried, AI Levey | 08/01/2023 |
bioRxiv : the preprint server for biology |
JV Santiago, A Natu, CC Ramelow, S Rayaprolu, H Xiao, V Kumar, NT Seyfried, S Rangaraju | 07/29/2023 |
A Molecular Basis of Human Brain Connectivity. bioRxiv : the preprint server for biology |
B Ng, S Tasaki, KM Greathouse, CK Walker, A Zhang, S Covitz, M Cieslak, AB Adamson, JP Andrade, EH Poovey, KA Curtis, HM Muhammad, J Seidlitz, T Satterthwaite, DA Bennett, NT Seyfried, J Vogel, C Gaiteri, JH Herskowitz | 07/24/2023 |
Molecular neurodegeneration |
ES Modeste, L Ping, CM Watson, DM Duong, EB Dammer, ECB Johnson, BR Roberts, JJ Lah, AI Levey, NT Seyfried | 07/19/2023 |
Science translational medicine |
YJ Sung, C Yang, J Norton, M Johnson, A Fagan, RJ Bateman, RJ Perrin, JC Morris, MR Farlow, JP Chhatwal, PR Schofield, H Chui, F Wang, B Novotny, A Eteleeb, C Karch, SE Schindler, H Rhinn, ECB Johnson, HS Oh, JE Rutledge, EB Dammer, NT Seyfried, T Wyss-Coray, O Harari, C Cruchaga | 07/05/2023 |
Genetic background influences the 5XFAD Alzheimer's disease mouse model brain proteome. bioRxiv : the preprint server for biology |
CD Hurst, AR Dunn, EB Dammer, DM Duong, NT Seyfried, CC Kaczorowski, ECB Johnson | 06/13/2023 |
Molecular & cellular proteomics : MCP |
S Sunna, C Bowen, H Zeng, S Rayaprolu, P Kumar, P Bagchi, EB Dammer, Q Guo, DM Duong, S Bitarafan, A Natu, L Wood, NT Seyfried, S Rangaraju | 06/01/2023 |
Neurobiology of aging |
M Seto, L Dumitrescu, ER Mahoney, AM Sclafani, PL De Jager, V Menon, MEI Koran, RA Robinson, DM Ruderfer, NJ Cox, NT Seyfried, AL Jefferson, JA Schneider, DA Bennett, VA Petyuk, TJ Hohman | 06/01/2023 |
bioRxiv : the preprint server for biology |
P Kumar, AM Goettemoeller, C Espinosa-Garcia, BR Tobin, A Tfaily, RS Nelson, A Natu, EB Dammer, JV Santiago, S Malepati, L Cheng, H Xiao, D Duong, NT Seyfried, LB Wood, MJ Rowan, S Rangaraju | 05/17/2023 |
The Journal of neuroscience : the official journal of the Society for Neuroscience |
CK Walker, KM Greathouse, JJ Tuscher, EB Dammer, AJ Weber, E Liu, KA Curtis, BD Boros, CD Freeman, JV Seo, R Ramdas, C Hurst, DM Duong, M Gearing, CF Murchison, JJ Day, NT Seyfried, JH Herskowitz | 05/17/2023 |
APOE expression and secretion are modulated by mitochondrial dysfunction. eLife |
ME Wynne, O Ogunbona, AR Lane, A Gokhale, SA Zlatic, C Xu, Z Wen, DM Duong, S Rayaprolu, A Ivanova, EA Ortlund, EB Dammer, NT Seyfried, BR Roberts, A Crocker, V Shanbhag, M Petris, N Senoo, S Kandasamy, SM Claypool, A Barrientos, A Wingo, TS Wingo, S Rangaraju, AI Levey, E Werner, V Faundez | 05/12/2023 |
Scientific data |
CM Watson, EB Dammer, L Ping, DM Duong, E Modeste, EK Carter, ECB Johnson, AI Levey, JJ Lah, BR Roberts, NT Seyfried | 05/09/2023 |
Molecular & cellular proteomics : MCP |
C Hurst, DA Pugh, MH Abreha, DM Duong, EB Dammer, DA Bennett, JH Herskowitz, NT Seyfried | 05/01/2023 |
PLoS genetics |
M Yu, H Ye, RB De-Paula, CG Mangleburg, T Wu, TV Lee, Y Li, D Duong, B Phillips, C Cruchaga, GI Allen, NT Seyfried, I Al-Ramahi, J Botas, JM Shulman | 05/01/2023 |
The landscape of metabolic brain alterations in Alzheimer's disease. Alzheimer's & dementia : the journal of the Alzheimer's Association |
R Batra, M Arnold, MA Wörheide, M Allen, X Wang, C Blach, AI Levey, NT Seyfried, N Ertekin-Taner, DA Bennett, G Kastenmüller, RF Kaddurah-Daouk, J Krumsiek | 03/01/2023 |
The journals of gerontology. Series A, Biological sciences and medical sciences |
AS Buchman, L Yu, HU Klein, AR Zammit, S Oveisgharan, F Grodstein, S Tasaki, AI Levey, NT Seyfried, DA Bennett | 03/01/2023 |
Research square |
R Tandon, L Zhao, CM Watson, M Elmor, C Heilman, K Sanders, CM Hales, H Yang, DW Loring, FC Goldstein, JJ Hanfelt, DM Duong, ECB Johnson, AP Wingo, TS Wingo, BR Roberts, NT Seyfried, AI Levey, CS Mitchell, JJ Lah | 02/28/2023 |
INPP5D/SHIP1 regulates inflammasome activation in human microglia. bioRxiv : the preprint server for biology |
V Chou, SB Fancher, RV Pearse, H Lee, M Lam, NT Seyfried, DA Bennett, PL De Jager, V Menon, TL Young-Pearse | 02/26/2023 |
bioRxiv : the preprint server for biology |
H Lee, AJ Aylward, RV Pearse, YC Hsieh, ZM Augur, CR Benoit, V Chou, A Knupp, C Pan, S Goberdhan, DM Duong, NT Seyfried, DA Bennett, HU Klein, PL De Jager, V Menon, JE Young, TL Young-Pearse | 02/25/2023 |
bioRxiv : the preprint server for biology |
NH Harbin, DJ Lustberg, C Hurst, JF Pare, KM Crotty, AL Waters, SM Yeligar, Y Smith, NT Seyfried, D Weinshenker, JR Hepler | 02/03/2023 |
Mis-spliced transcripts generate de novo proteins in TDP-43-related ALS/FTD. bioRxiv : the preprint server for biology |
S Seddighi, YA Qi, AL Brown, OG Wilkins, C Bereda, C Belair, Y Zhang, M Prudencio, MJ Keuss, A Khandeshi, S Pickles, SE Hill, J Hawrot, DM Ramos, H Yuan, J Roberts, E Kelmer Sacramento, SI Shah, MA Nalls, J Colon-Mercado, JF Reyes, VH Ryan, MP Nelson, C Cook, Z Li, L Screven, JY Kwan, A Shantaraman, L Ping, Y Koike, B Oskarsson, N Staff, DM Duong, A Ahmed, M Secrier, J Ule, S Jacobson, J Rohrer, A Malaspina, JD Glass, A Ori, NT Seyfried, M Maragkakis, L Petrucelli, P Fratta, ME Ward | 01/23/2023 |
Alzheimer's & dementia (New York, N. Y.) |
SJ Sukoff Rizzo, G Homanics, DJ Schaeffer, L Schaeffer, JE Park, J Oluoch, T Zhang, A Haber, NT Seyfried, B Paten, A Greenwood, T Murai, SH Choi, H Huhe, J Kofler, PL Strick, GW Carter, AC Silva | 01/01/2023 |
Genetic background influences the 5XFAD Alzheimer's disease mouse model brain proteome. Frontiers in aging neuroscience |
CD Hurst, AR Dunn, EB Dammer, DM Duong, SM Shapley, NT Seyfried, CC Kaczorowski, ECB Johnson | 01/01/2023 |
Batch Correction and Harmonization of -Omics Datasets with a Tunable Median Polish of Ratio. Frontiers in systems biology |
EB Dammer, NT Seyfried, ECB Johnson | 01/01/2023 |
Journal of Alzheimer's disease : JAD |
R Tandon, AI Levey, JJ Lah, NT Seyfried, CS Mitchell | 01/01/2023 |
Glycoproteomics Landscape of Asymptomatic and Symptomatic Human Alzheimer's Disease Brain. Molecular & cellular proteomics : MCP |
S Suttapitugsakul, K Stavenhagen, S Donskaya, DA Bennett, RG Mealer, NT Seyfried, RD Cummings | 12/01/2022 |
Alzheimer's research & therapy |
EB Dammer, L Ping, DM Duong, ES Modeste, NT Seyfried, JJ Lah, AI Levey, ECB Johnson | 11/17/2022 |
Association of AK4 Protein From Stem Cell-Derived Neurons With Cognitive Reserve: An Autopsy Study. Neurology |
L Yu, YC Hsieh, RV Pearse, Y Wang, VA Petyuk, JA Schneider, AS Buchman, NT Seyfried, PL De Jager, TL Young-Pearse, DA Bennett | 11/15/2022 |
Metabolites |
AL Sohn, L Ping, JD Glass, NT Seyfried, EC Hector, DC Muddiman | 11/10/2022 |
Nature communications |
P Kapoor-Vazirani, SK Rath, X Liu, Z Shu, NE Bowen, Y Chen, R Haji-Seyed-Javadi, W Daddacha, EV Minten, D Danelia, D Farchi, DM Duong, NT Seyfried, X Deng, EA Ortlund, B Kim, DS Yu | 11/07/2022 |
Nature aging |
M Del Campo, CFW Peeters, ECB Johnson, L Vermunt, YS Hok-A-Hin, M van Nee, A Chen-Plotkin, DJ Irwin, WT Hu, JJ Lah, NT Seyfried, EB Dammer, G Herradon, LH Meeter, J van Swieten, D Alcolea, A Lleó, AI Levey, AW Lemstra, YAL Pijnenburg, PJ Visser, BM Tijms, WM van der Flier, CE Teunissen | 11/01/2022 |
Molecular neurodegeneration |
YC Hsieh, J Negri, A He, RV Pearse, L Liu, DM Duong, LB Chibnik, DA Bennett, NT Seyfried, TL Young-Pearse | 09/21/2022 |
The Journal of biological chemistry |
MA Johnson, TA Nuckols, P Merino, P Bagchi, S Nandy, J Root, G Taylor, NT Seyfried, T Kukar | 08/01/2022 |
Shared mechanisms across the major psychiatric and neurodegenerative diseases. Nature communications |
TS Wingo, Y Liu, ES Gerasimov, SM Vattathil, ME Wynne, J Liu, A Lori, V Faundez, DA Bennett, NT Seyfried, AI Levey, AP Wingo | 07/26/2022 |
Genetic Evidence Supporting a Causal Role of Depression in Alzheimer's Disease. Biological psychiatry |
NV Harerimana, Y Liu, ES Gerasimov, D Duong, TG Beach, EM Reiman, JA Schneider, P Boyle, A Lori, DA Bennett, JJ Lah, AI Levey, NT Seyfried, TS Wingo, AP Wingo | 07/01/2022 |
Molecular psychiatry |
TS Wingo, ES Gerasimov, Y Liu, DM Duong, SM Vattathil, A Lori, J Gockley, MS Breen, AX Maihofer, CM Nievergelt, KC Koenen, DF Levey, J Gelernter, MB Stein, KJ Ressler, DA Bennett, AI Levey, NT Seyfried, AP Wingo | 07/01/2022 |
A phase II study repurposing atomoxetine for neuroprotection in mild cognitive impairment. Brain : a journal of neurology |
AI Levey, D Qiu, L Zhao, WT Hu, DM Duong, L Higginbotham, EB Dammer, NT Seyfried, TS Wingo, CM Hales, M Gámez Tansey, DS Goldstein, A Abrol, VD Calhoun, FC Goldstein, I Hajjar, AM Fagan, D Galasko, SD Edland, J Hanfelt, JJ Lah, D Weinshenker | 06/30/2022 |
eLife |
VJ Olah, AM Goettemoeller, S Rayaprolu, EB Dammer, NT Seyfried, S Rangaraju, J Dimidschstein, MJM Rowan | 06/21/2022 |
Signatures of glial activity can be detected in the CSF proteome. Proceedings of the National Academy of Sciences of the United States of America |
T Eninger, SA Müller, M Bacioglu, M Schweighauser, M Lambert, LF Maia, JJ Neher, SM Hornfeck, U Obermüller, G Kleinberger, C Haass, PJ Kahle, M Staufenbiel, L Ping, DM Duong, AI Levey, NT Seyfried, SF Lichtenthaler, M Jucker, SA Kaeser | 06/14/2022 |
Nature communications |
S Rayaprolu, S Bitarafan, JV Santiago, R Betarbet, S Sunna, L Cheng, H Xiao, RS Nelson, P Kumar, P Bagchi, DM Duong, AM Goettemoeller, VJ Oláh, M Rowan, AI Levey, LB Wood, NT Seyfried, S Rangaraju | 05/25/2022 |
Mitochondrial respiratory chain protein co-regulation in the human brain. Heliyon |
C Trumpff, E Owusu-Ansah, HU Klein, AJ Lee, V Petyuk, TS Wingo, AP Wingo, M Thambisetty, L Ferrucci, NT Seyfried, DA Bennett, PL De Jager, M Picard | 05/01/2022 |
Molecular psychiatry |
CI Wu, EA Vinton, RV Pearse, K Heo, AJ Aylward, YC Hsieh, Y Bi, S Adeleye, S Fancher, DM Duong, NT Seyfried, TL Schwarz, TL Young-Pearse | 04/01/2022 |
Quantitative proteomic analysis of the lysine acetylome reveals diverse SIRT2 substrates. Scientific reports |
H Zhang, EB Dammer, DM Duong, D Danelia, NT Seyfried, DS Yu | 03/09/2022 |
Neuropathologic Correlates of Human Cortical Proteins in Alzheimer Disease and Related Dementias. Neurology |
L Yu, PA Boyle, AP Wingo, J Yang, T Wang, AS Buchman, TS Wingo, NT Seyfried, AI Levey, PL De Jager, JA Schneider, DA Bennett | 03/08/2022 |
Nature neuroscience |
ECB Johnson, EK Carter, EB Dammer, DM Duong, ES Gerasimov, Y Liu, J Liu, R Betarbet, L Ping, L Yin, GE Serrano, TG Beach, J Peng, PL De Jager, V Haroutunian, B Zhang, C Gaiteri, DA Bennett, M Gearing, TS Wingo, AP Wingo, JJ Lah, AI Levey, NT Seyfried | 02/01/2022 |
Brain microRNAs are associated with variation in cognitive trajectory in advanced age. Translational psychiatry |
AP Wingo, M Wang, J Liu, MS Breen, HS Yang, B Tang, JA Schneider, NT Seyfried, JJ Lah, AI Levey, DA Bennett, P Jin, PL De Jager, TS Wingo | 02/01/2022 |
The Journal of clinical investigation |
X Wang, M Allen, Ö İş, JS Reddy, FQ Tutor-New, M Castanedes Casey, MM Carrasquillo, SR Oatman, Y Min, YW Asmann, C Funk, T Nguyen, CC Ho, KG Malphrus, NT Seyfried, AI Levey, SG Younkin, ME Murray, DW Dickson, ND Price, TE Golde, N Ertekin-Taner | 01/18/2022 |
Exploring Cortical Proteins Underlying the Relation of Neuroticism to Cognitive Resilience. Aging brain |
F Grodstein, L Yu, PL de Jager, A Levey, NT Seyfried, DA Bennett | 01/01/2022 |
Frontiers in neuroscience |
RS Nelson, EB Dammer, JV Santiago, NT Seyfried, S Rangaraju | 01/01/2022 |
Posttranslational Modifications Mediate the Structural Diversity of Tauopathy Strains. Cell |
T Arakhamia, CE Lee, Y Carlomagno, M Kumar, DM Duong, H Wesseling, SR Kundinger, K Wang, D Williams, M DeTure, DW Dickson, CN Cook, NT Seyfried, L Petrucelli, JA Steen, AWP Fitzpatrick | 12/09/2021 |
Insights into the changes in the proteome of Alzheimer disease elucidated by a meta-analysis. Scientific data |
H Haytural, R Benfeitas, S Schedin-Weiss, E Bereczki, M Rezeli, RD Unwin, X Wang, EB Dammer, ECB Johnson, NT Seyfried, B Winblad, BM Tijms, PJ Visser, S Frykman, LO Tjernberg | 12/03/2021 |
Nature communications |
Y Ma, EB Dammer, D Felsky, DM Duong, HU Klein, CC White, M Zhou, BA Logsdon, C McCabe, J Xu, M Wang, TS Wingo, JJ Lah, B Zhang, J Schneider, M Allen, X Wang, N Ertekin-Taner, NT Seyfried, AI Levey, DA Bennett, PL De Jager | 12/02/2021 |
Neuron |
VN Lagomarsino, RV Pearse, L Liu, YC Hsieh, MA Fernandez, EA Vinton, D Paull, D Felsky, S Tasaki, C Gaiteri, B Vardarajan, H Lee, CR Muratore, CR Benoit, V Chou, SB Fancher, A He, JP Merchant, DM Duong, H Martinez, M Zhou, F Bah, MA Vicent, JMS Stricker, J Xu, EB Dammer, AI Levey, LB Chibnik, V Menon, NT Seyfried, PL De Jager, S Noggle, DJ Selkoe, DA Bennett, TL Young-Pearse | 11/03/2021 |
FASEB journal : official publication of the Federation of American Societies for Experimental Biology |
Y Wang, R Liu, J Liao, L Jiang, GH Jeong, L Zhou, M Polite, D Duong, NT Seyfried, H Wang, H Kiyokawa, J Yin | 11/01/2021 |
Phosphorylation regulates arginine-rich RNA-binding protein solubility and oligomerization. The Journal of biological chemistry |
SR Kundinger, EB Dammer, L Yin, C Hurst, S Shapley, L Ping, S Khoshnevis, H Ghalei, DM Duong, NT Seyfried | 11/01/2021 |
Scientific reports |
R Gorkhali, L Tian, B Dong, P Bagchi, X Deng, S Pawar, D Duong, N Fang, N Seyfried, J Yang | 10/18/2021 |
Alzheimer's research & therapy |
K Borkowski, TL Pedersen, NT Seyfried, JJ Lah, AI Levey, CM Hales, EB Dammer, C Blach, G Louie, R Kaddurah-Daouk, JW Newman | 09/06/2021 |
American journal of physiology. Cell physiology |
JN Peoples, N Ghazal, DM Duong, KR Hardin, JR Manning, NT Seyfried, V Faundez, JQ Kwong | 09/01/2021 |
Mitochondrial Proteostasis Requires Genes Encoded in a Neurodevelopmental Syndrome Locus. The Journal of neuroscience : the official journal of the Society for Neuroscience |
A Gokhale, CE Lee, SA Zlatic, AAH Freeman, N Shearing, C Hartwig, O Ogunbona, JL Bassell, ME Wynne, E Werner, C Xu, Z Wen, D Duong, NT Seyfried, CE Bearden, VJ Oláh, MJM Rowan, JR Glausier, DA Lewis, V Faundez | 08/04/2021 |
Omics sciences for systems biology in Alzheimer's disease: State-of-the-art of the evidence. Ageing research reviews |
H Hampel, R Nisticò, NT Seyfried, AI Levey, E Modeste, P Lemercier, F Baldacci, N Toschi, F Garaci, G Perry, E Emanuele, PL Valenzuela, A Lucia, A Urbani, GM Sancesario, M Mapstone, M Corbo, A Vergallo, S Lista | 08/01/2021 |
Molecular neurodegeneration |
L Gutierrez-Quiceno, EB Dammer, AG Johnson, JA Webster, R Shah, D Duong, L Yin, NT Seyfried, VE Alvarez, TD Stein, AC McKee, CM Hales | 06/25/2021 |
Alzheimer's & dementia : the journal of the Alzheimer's Association |
HD Li, CC Funk, K McFarland, EB Dammer, M Allen, MM Carrasquillo, Y Levites, P Chakrabarty, JD Burgess, X Wang, D Dickson, NT Seyfried, DM Duong, JJ Lah, SG Younkin, AI Levey, GS Omenn, N Ertekin-Taner, TE Golde, ND Price | 06/01/2021 |
Extracellular signal-regulated kinase regulates microglial immune responses in Alzheimer's disease. Journal of neuroscience research |
MJ Chen, S Ramesha, LD Weinstock, T Gao, L Ping, H Xiao, EB Dammer, DD Duong, AI Levey, JJ Lah, NT Seyfried, LB Wood, S Rangaraju | 06/01/2021 |
Brain proteome-wide association study implicates novel proteins in depression pathogenesis. Nature neuroscience |
TS Wingo, Y Liu, ES Gerasimov, J Gockley, BA Logsdon, DM Duong, EB Dammer, A Lori, PJ Kim, KJ Ressler, TG Beach, EM Reiman, MP Epstein, PL De Jager, JJ Lah, DA Bennett, NT Seyfried, AI Levey, AP Wingo | 06/01/2021 |
A Genetic Study of Cerebral Atherosclerosis Reveals Novel Associations with NTNG1 and CNOT3. Genes |
SM Vattathil, Y Liu, NV Harerimana, A Lori, ES Gerasimov, TG Beach, EM Reiman, PL De Jager, JA Schneider, DA Bennett, NT Seyfried, AI Levey, AP Wingo, TS Wingo | 05/26/2021 |
iScience |
CD Dill, EB Dammer, TL Griffen, NT Seyfried, JW Lillard | 05/21/2021 |
Alzheimer's research & therapy |
LE Donovan, EB Dammer, DM Duong, JJ Hanfelt, AI Levey, NT Seyfried, JJ Lah | 05/18/2021 |
Proceedings of the National Academy of Sciences of the United States of America |
S Ramesha, S Rayaprolu, CA Bowen, CR Giver, S Bitarafan, HM Nguyen, T Gao, MJ Chen, N Nwabueze, EB Dammer, AK Engstrom, H Xiao, A Pennati, NT Seyfried, DJ Katz, J Galipeau, H Wulff, EK Waller, LB Wood, AI Levey, S Rangaraju | 03/16/2021 |
Genetic control of the human brain proteome. American journal of human genetics |
C Robins, Y Liu, W Fan, DM Duong, J Meigs, NV Harerimana, ES Gerasimov, EB Dammer, DJ Cutler, TG Beach, EM Reiman, PL De Jager, DA Bennett, JJ Lah, AP Wingo, AI Levey, NT Seyfried, TS Wingo | 03/04/2021 |
Nature genetics |
AP Wingo, Y Liu, ES Gerasimov, J Gockley, BA Logsdon, DM Duong, EB Dammer, C Robins, TG Beach, EM Reiman, MP Epstein, PL De Jager, JJ Lah, DA Bennett, NT Seyfried, AI Levey, TS Wingo | 02/01/2021 |
Broad Kinase Inhibition Mitigates Early Neuronal Dysfunction in Tauopathy. International journal of molecular sciences |
SA Koren, MJ Hamm, R Cloyd, SN Fontaine, E Chishti, C Lanzillotta, J Rodriguez-Rivera, A Ingram, M Bell, SM Galvis-Escobar, N Zulia, F Di Domenico, D Duong, NT Seyfried, D Powell, M Vandsburger, T Frolinger, AMS Hartz, J Koren, JM Axten, NJ Laping, JF Abisambra | 01/26/2021 |
Frontiers in molecular neuroscience |
Q Guo, EB Dammer, M Zhou, SR Kundinger, M Gearing, JJ Lah, AI Levey, JM Shulman, NT Seyfried | 01/01/2021 |
Systems-based proteomics to resolve the biology of Alzheimer's disease beyond amyloid and tau. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology |
S Rayaprolu, L Higginbotham, P Bagchi, CM Watson, T Zhang, AI Levey, S Rangaraju, NT Seyfried | 01/01/2021 |
TBK1 interacts with tau and enhances neurodegeneration in tauopathy. The Journal of biological chemistry |
MH Abreha, S Ojelade, EB Dammer, ZT McEachin, DM Duong, M Gearing, GJ Bassell, JJ Lah, AI Levey, JM Shulman, NT Seyfried | 01/01/2021 |
Cortical Proteins Associated With Cognitive Resilience in Community-Dwelling Older Persons. JAMA psychiatry |
L Yu, S Tasaki, JA Schneider, K Arfanakis, DM Duong, AP Wingo, TS Wingo, N Kearns, GRJ Thatcher, NT Seyfried, AI Levey, PL De Jager, DA Bennett | 11/01/2020 |
Acta neuropathologica communications |
M Huang, E Modeste, E Dammer, P Merino, G Taylor, DM Duong, Q Deng, CJ Holler, M Gearing, D Dickson, NT Seyfried, T Kukar | 10/07/2020 |
Science advances |
L Higginbotham, L Ping, EB Dammer, DM Duong, M Zhou, M Gearing, C Hurst, JD Glass, SA Factor, ECB Johnson, I Hajjar, JJ Lah, AI Levey, NT Seyfried | 10/01/2020 |
Integrated analysis of the aging brain transcriptome and proteome in tauopathy. Molecular neurodegeneration |
CG Mangleburg, T Wu, HK Yalamanchili, C Guo, YC Hsieh, DM Duong, EB Dammer, PL De Jager, NT Seyfried, Z Liu, JM Shulman | 09/29/2020 |
Global quantitative analysis of the human brain proteome and phosphoproteome in Alzheimer's disease. Scientific data |
L Ping, SR Kundinger, DM Duong, L Yin, M Gearing, JJ Lah, AI Levey, NT Seyfried | 09/28/2020 |
Multiscale causal networks identify VGF as a key regulator of Alzheimer's disease. Nature communications |
ND Beckmann, WJ Lin, M Wang, AT Cohain, AW Charney, P Wang, W Ma, YC Wang, C Jiang, M Audrain, PH Comella, AK Fakira, SP Hariharan, GM Belbin, K Girdhar, AI Levey, NT Seyfried, EB Dammer, D Duong, JJ Lah, JV Haure-Mirande, B Shackleton, T Fanutza, R Blitzer, E Kenny, J Zhu, V Haroutunian, P Katsel, S Gandy, Z Tu, ME Ehrlich, B Zhang, SR Salton, EE Schadt | 08/07/2020 |
Nature neuroscience |
AP Wingo, W Fan, DM Duong, ES Gerasimov, EB Dammer, Y Liu, NV Harerimana, B White, M Thambisetty, JC Troncoso, N Kim, JA Schneider, IM Hajjar, JJ Lah, DA Bennett, NT Seyfried, AI Levey, TS Wingo | 08/01/2020 |
Proteomic Analysis of Human Immune Responses to Live-Attenuated Tularemia Vaccine. Vaccines |
YH Chang, DM Duong, JB Goll, DC Wood, TL Jensen, L Yin, CE Gelber, NT Seyfried, E Anderson, MS Natrajan, N Rouphael, RA Johnson, P Sanz, MJ Mulligan, DF Hoft | 07/24/2020 |
Identification of Conserved Proteomic Networks in Neurodegenerative Dementia. Cell reports |
V Swarup, TS Chang, DM Duong, EB Dammer, J Dai, JJ Lah, ECB Johnson, NT Seyfried, AI Levey, DH Geschwind | 06/23/2020 |
Shared proteomic effects of cerebral atherosclerosis and Alzheimer's disease on the human brain. Nature neuroscience |
AP Wingo, W Fan, DM Duong, ES Gerasimov, EB Dammer, Y Liu, NV Harerimana, B White, M Thambisetty, JC Troncoso, N Kim, JA Schneider, IM Hajjar, JJ Lah, DA Bennett, NT Seyfried, AI Levey, TS Wingo | 06/01/2020 |
Oncogene |
AE Koyen, MZ Madden, D Park, EV Minten, P Kapoor-Vazirani, E Werner, NT Pfister, R Haji-Seyed-Javadi, H Zhang, J Xu, N Deng, DM Duong, TJ Pecen, Z Frazier, ZD Nagel, JB Lazaro, KW Mouw, NT Seyfried, CS Moreno, TK Owonikoko, X Deng, DS Yu | 06/01/2020 |
Molecular neurodegeneration |
S Rayaprolu, T Gao, H Xiao, S Ramesha, LD Weinstock, J Shah, DM Duong, EB Dammer, JA Webster, JJ Lah, LB Wood, R Betarbet, AI Levey, NT Seyfried, S Rangaraju | 05/07/2020 |
Nature medicine |
ECB Johnson, EB Dammer, DM Duong, L Ping, M Zhou, L Yin, LA Higginbotham, A Guajardo, B White, JC Troncoso, M Thambisetty, TJ Montine, EB Lee, JQ Trojanowski, TG Beach, EM Reiman, V Haroutunian, M Wang, E Schadt, B Zhang, DW Dickson, N Ertekin-Taner, TE Golde, VA Petyuk, PL De Jager, DA Bennett, TS Wingo, S Rangaraju, I Hajjar, JM Shulman, JJ Lah, AI Levey, NT Seyfried | 05/01/2020 |
Journal of proteome research |
SR Kundinger, I Bishof, EB Dammer, DM Duong, NT Seyfried | 04/03/2020 |
Posttranslational Modifications Mediate the Structural Diversity of Tauopathy Strains. Cell |
T Arakhamia, CE Lee, Y Carlomagno, DM Duong, SR Kundinger, K Wang, D Williams, M DeTure, DW Dickson, CN Cook, NT Seyfried, L Petrucelli, AWP Fitzpatrick | 02/20/2020 |
Journal of proteome research |
TT Nguyen, EB Dammer, SA Owino, MM Giddens, NS Madaras, DM Duong, NT Seyfried, RA Hall | 02/07/2020 |
Alzheimer's & dementia (New York, N. Y.) |
MP Vitek, JA Araujo, M Fossel, BD Greenberg, GR Howell, SJS Rizzo, NT Seyfried, AJ Tenner, PR Territo, M Windisch, LJ Bain, A Ross, MC Carrillo, BT Lamb, RM Edelmayer | 01/01/2020 |
Clinical proteomics |
M Zhou, RU Haque, EB Dammer, DM Duong, L Ping, ECB Johnson, JJ Lah, AI Levey, NT Seyfried | 01/01/2020 |
Molecular Signatures of Neuroinflammation Induced by αSynuclein Aggregates in Microglial Cells. Frontiers in immunology |
S Sarkar, EB Dammer, E Malovic, AL Olsen, SA Raza, T Gao, H Xiao, DL Oliver, D Duong, V Joers, N Seyfried, M Huang, T Kukar, MG Tansey, AG Kanthasamy, S Rangaraju | 01/01/2020 |
NPJ genomic medicine |
TS Wingo, J Yang, W Fan, S Min Canon, ES Gerasimov, A Lori, B Logsdon, B Yao, NT Seyfried, JJ Lah, AI Levey, PA Boyle, JA Schneider, PL De Jager, DA Bennett, AP Wingo | 01/01/2020 |
Cell reports |
YC Hsieh, C Guo, HK Yalamanchili, M Abreha, R Al-Ouran, Y Li, EB Dammer, JJ Lah, AI Levey, DA Bennett, PL De Jager, NT Seyfried, Z Liu, JM Shulman | 10/08/2019 |
Glia |
T Gao, J Jernigan, SA Raza, EB Dammer, H Xiao, NT Seyfried, AI Levey, S Rangaraju | 10/01/2019 |
Ionizing Radiation induction of cholesterol biosynthesis in Lung tissue. Scientific reports |
E Werner, A Alter, Q Deng, EB Dammer, Y Wang, DS Yu, DM Duong, NT Seyfried, PW Doetsch | 08/29/2019 |
Network Analysis of a Membrane-Enriched Brain Proteome across Stages of Alzheimer's Disease. Proteomes |
L Higginbotham, EB Dammer, DM Duong, E Modeste, TJ Montine, JJ Lah, AI Levey, NT Seyfried | 08/27/2019 |
Journal of proteome research |
M Zhou, DM Duong, ECB Johnson, J Dai, JJ Lah, AI Levey, NT Seyfried | 06/07/2019 |
Journal of proteome research |
KJ Gerber, EB Dammer, DM Duong, Q Deng, SM Dudek, NT Seyfried, JR Hepler | 06/07/2019 |
The Journal of biological chemistry |
A Banerjee, BL Phillips, Q Deng, NT Seyfried, GK Pavlath, KE Vest, AH Corbett | 05/03/2019 |
The Journal of neuroscience : the official journal of the Society for Neuroscience |
A Gokhale, C Hartwig, AAH Freeman, JL Bassell, SA Zlatic, C Sapp Savas, T Vadlamudi, F Abudulai, TT Pham, A Crocker, E Werner, Z Wen, GM Repetto, JA Gogos, SM Claypool, JK Forsyth, CE Bearden, J Glausier, DA Lewis, NT Seyfried, JQ Kwong, V Faundez | 05/01/2019 |
Nature communications |
AP Wingo, EB Dammer, MS Breen, BA Logsdon, DM Duong, JC Troncosco, M Thambisetty, TG Beach, GE Serrano, EM Reiman, RJ Caselli, JJ Lah, NT Seyfried, AI Levey, TS Wingo | 04/08/2019 |
Identification of evolutionarily conserved gene networks mediating neurodegenerative dementia. Nature medicine |
V Swarup, FI Hinz, JE Rexach, KI Noguchi, H Toyoshiba, A Oda, K Hirai, A Sarkar, NT Seyfried, C Cheng, SJ Haggarty, M Grossman, VM Van Deerlin, JQ Trojanowski, JJ Lah, AI Levey, S Kondou, DH Geschwind | 01/01/2019 |
Translational psychiatry |
P Srikanth, VN Lagomarsino, RV Pearse, M Liao, S Ghosh, R Nehme, N Seyfried, K Eggan, TL Young-Pearse | 11/08/2018 |
Molecular neurodegeneration |
ECB Johnson, EB Dammer, DM Duong, L Yin, M Thambisetty, JC Troncoso, JJ Lah, AI Levey, NT Seyfried | 10/04/2018 |
Quantitative Analysis of the Brain Ubiquitylome in Alzheimer's Disease. Proteomics |
MH Abreha, EB Dammer, L Ping, T Zhang, DM Duong, M Gearing, JJ Lah, AI Levey, NT Seyfried | 10/01/2018 |
Scientific data |
M Wang, ND Beckmann, P Roussos, E Wang, X Zhou, Q Wang, C Ming, R Neff, W Ma, JF Fullard, ME Hauberg, J Bendl, MA Peters, B Logsdon, P Wang, M Mahajan, LM Mangravite, EB Dammer, DM Duong, JJ Lah, NT Seyfried, AI Levey, JD Buxbaum, M Ehrlich, S Gandy, P Katsel, V Haroutunian, E Schadt, B Zhang | 09/11/2018 |
The Journal of biological chemistry |
I Bishof, EB Dammer, DM Duong, SR Kundinger, M Gearing, JJ Lah, AI Levey, NT Seyfried | 07/13/2018 |
Molecular neurodegeneration |
S Rangaraju, EB Dammer, SA Raza, T Gao, H Xiao, R Betarbet, DM Duong, JA Webster, CM Hales, JJ Lah, AI Levey, NT Seyfried | 06/28/2018 |
Molecular neurodegeneration |
S Rangaraju, EB Dammer, SA Raza, P Rathakrishnan, H Xiao, T Gao, DM Duong, MW Pennington, JJ Lah, NT Seyfried, AI Levey | 05/21/2018 |
Journal of proteome research |
PR Evans, KJ Gerber, EB Dammer, DM Duong, D Goswami, DJ Lustberg, J Zou, JJ Yang, SM Dudek, PR Griffin, NT Seyfried, JR Hepler | 04/06/2018 |
Global quantitative analysis of the human brain proteome in Alzheimer's and Parkinson's Disease. Scientific data |
L Ping, DM Duong, L Yin, M Gearing, JJ Lah, AI Levey, NT Seyfried | 03/13/2018 |
Alzheimer's & dementia : the journal of the Alzheimer's Association |
M Allen, X Wang, JD Burgess, J Watzlawik, DJ Serie, CS Younkin, T Nguyen, KG Malphrus, S Lincoln, MM Carrasquillo, C Ho, P Chakrabarty, S Strickland, ME Murray, V Swarup, DH Geschwind, NT Seyfried, EB Dammer, JJ Lah, AI Levey, TE Golde, C Funk, H Li, ND Price, RC Petersen, NR Graff-Radford, SG Younkin, DW Dickson, JR Crook, YW Asmann, N Ertekin-Taner | 03/01/2018 |
Evidence for brain glucose dysregulation in Alzheimer's disease. Alzheimer's & dementia : the journal of the Alzheimer's Association |
Y An, VR Varma, S Varma, R Casanova, E Dammer, O Pletnikova, CW Chia, JM Egan, L Ferrucci, J Troncoso, AI Levey, J Lah, NT Seyfried, C Legido-Quigley, R O'Brien, M Thambisetty | 03/01/2018 |
TDP-43 pathology disrupts nuclear pore complexes and nucleocytoplasmic transport in ALS/FTD. Nature neuroscience |
CC Chou, Y Zhang, ME Umoh, SW Vaughan, I Lorenzini, F Liu, M Sayegh, PG Donlin-Asp, YH Chen, DM Duong, NT Seyfried, MA Powers, T Kukar, CM Hales, M Gearing, NJ Cairns, KB Boylan, DW Dickson, R Rademakers, YJ Zhang, L Petrucelli, R Sattler, DC Zarnescu, JD Glass, W Rossoll | 02/01/2018 |
EMBO molecular medicine |
ME Umoh, EB Dammer, J Dai, DM Duong, JJ Lah, AI Levey, M Gearing, JD Glass, NT Seyfried | 01/01/2018 |
Frontiers in immunology |
S Rangaraju, SA Raza, NX Li, R Betarbet, EB Dammer, D Duong, JJ Lah, NT Seyfried, AI Levey | 01/01/2018 |
Effects of APOE Genotype on Brain Proteomic Network and Cell Type Changes in Alzheimer's Disease. Frontiers in molecular neuroscience |
J Dai, ECB Johnson, EB Dammer, DM Duong, M Gearing, JJ Lah, AI Levey, TS Wingo, NT Seyfried | 01/01/2018 |
Characterization of Detergent Insoluble Proteome in Chronic Traumatic Encephalopathy. Journal of neuropathology and experimental neurology |
JD Cherry, A Zeineddin, EB Dammer, JA Webster, D Duong, NT Seyfried, AI Levey, VE Alvarez, BR Huber, TD Stein, PT Kiernan, AC McKee, JJ Lah, CM Hales | 01/01/2018 |
Identifying the substrate proteins of U-box E3s E4B and CHIP by orthogonal ubiquitin transfer. Science advances |
K Bhuripanyo, Y Wang, X Liu, L Zhou, R Liu, D Duong, B Zhao, Y Bi, H Zhou, G Chen, NT Seyfried, WJ Chazin, H Kiyokawa, J Yin | 01/01/2018 |
Molecular neurodegeneration |
AT McKenzie, S Moyon, M Wang, I Katsyv, WM Song, X Zhou, EB Dammer, DM Duong, J Aaker, Y Zhao, N Beckmann, P Wang, J Zhu, JJ Lah, NT Seyfried, AI Levey, P Katsel, V Haroutunian, EE Schadt, B Popko, P Casaccia, B Zhang | 11/06/2017 |
Enrichment of Detergent-insoluble Protein Aggregates from Human Postmortem Brain. Journal of visualized experiments : JoVE |
I Diner, T Nguyen, NT Seyfried | 10/24/2017 |
Bioconjugate chemistry |
I Diner, J Dooyema, M Gearing, LC Walker, NT Seyfried | 10/18/2017 |
Human molecular genetics |
J Rha, SK Jones, J Fidler, A Banerjee, SW Leung, KJ Morris, JC Wong, GAS Inglis, L Shapiro, Q Deng, AA Cutler, AM Hanif, MT Pardue, A Schaffer, NT Seyfried, KH Moberg, GJ Bassell, A Escayg, PS García, AH Corbett | 10/01/2017 |
Journal of proteome research |
TS Wingo, DM Duong, M Zhou, EB Dammer, H Wu, DJ Cutler, JJ Lah, AI Levey, NT Seyfried | 09/01/2017 |
Aging cell |
AA Cutler, EB Dammer, DM Doung, NT Seyfried, AH Corbett, GK Pavlath | 08/01/2017 |
Nature structural & molecular biology |
Z Zhang, SS Kang, X Liu, EH Ahn, Z Zhang, L He, PM Iuvone, DM Duong, NT Seyfried, MJ Benskey, FP Manfredsson, L Jin, YE Sun, JZ Wang, K Ye | 08/01/2017 |
The Journal of biological chemistry |
AA Ivanova, T Caspary, NT Seyfried, DM Duong, AB West, Z Liu, RA Kahn | 06/30/2017 |
Journal of neuroinflammation |
S Rangaraju, SA Raza, A Pennati, Q Deng, EB Dammer, D Duong, MW Pennington, MG Tansey, JJ Lah, R Betarbet, NT Seyfried, AI Levey | 06/26/2017 |
Cell systems |
NT Seyfried, EB Dammer, V Swarup, D Nandakumar, DM Duong, L Yin, Q Deng, T Nguyen, CM Hales, T Wingo, J Glass, M Gearing, M Thambisetty, JC Troncoso, DH Geschwind, JJ Lah, AI Levey | 01/25/2017 |
The State of Systems Genetics in 2017. Cell systems |
NS Baliga, JL Björkegren, JD Boeke, M Boutros, NP Crawford, AM Dudley, CR Farber, A Jones, AI Levey, AJ Lusis, HC Mak, JH Nadeau, MB Noyes, E Petretto, NT Seyfried, LM Steinmetz, SC Vonesch | 01/25/2017 |
eNeuro |
Y Li, EB Dammer, X Zhang-Brotzge, S Chen, DM Duong, NT Seyfried, CY Kuan, YY Sun | 01/01/2017 |
Proteomics |
CM Hales, EB Dammer, Q Deng, DM Duong, M Gearing, JC Troncoso, M Thambisetty, JJ Lah, JM Shulman, AI Levey, NT Seyfried | 12/01/2016 |
Molecular and cellular biology |
S Soucek, Y Zeng, DL Bellur, M Bergkessel, KJ Morris, Q Deng, D Duong, NT Seyfried, C Guthrie, JP Staley, MB Fasken, AH Corbett | 11/01/2016 |
CSF complement 3 and factor H are staging biomarkers in Alzheimer's disease. Acta neuropathologica communications |
WT Hu, KD Watts, P Tailor, TP Nguyen, JC Howell, RC Lee, NT Seyfried, M Gearing, CM Hales, AI Levey, JJ Lah, EK Lee | 02/17/2016 |
ATRIP Deacetylation by SIRT2 Drives ATR Checkpoint Activation by Promoting Binding to RPA-ssDNA. Cell reports |
H Zhang, PE Head, W Daddacha, SH Park, X Li, Y Pan, MZ Madden, DM Duong, M Xie, B Yu, MD Warren, EA Liu, VR Dhere, C Li, I Pradilla, MA Torres, Y Wang, WS Dynan, PW Doetsch, X Deng, NT Seyfried, D Gius, DS Yu | 02/16/2016 |
Pseudomonas aeruginosa EftM Is a Thermoregulated Methyltransferase. The Journal of biological chemistry |
JP Owings, EG Kuiper, SM Prezioso, J Meisner, JJ Varga, N Zelinskaya, EB Dammer, DM Duong, NT Seyfried, S Albertí, GL Conn, JB Goldberg | 02/12/2016 |
FUS is phosphorylated by DNA-PK and accumulates in the cytoplasm after DNA damage. The Journal of neuroscience : the official journal of the Society for Neuroscience |
Q Deng, CJ Holler, G Taylor, KF Hudson, W Watkins, M Gearing, D Ito, ME Murray, DW Dickson, NT Seyfried, T Kukar | 06/04/2014 |
The Journal of neuroscience : the official journal of the Society for Neuroscience |
JH Herskowitz, Y Feng, AL Mattheyses, CM Hales, LA Higginbotham, DM Duong, TJ Montine, JC Troncoso, M Thambisetty, NT Seyfried, AI Levey, JJ Lah | 12/04/2013 |
U1 small nuclear ribonucleoprotein complex and RNA splicing alterations in Alzheimer's disease. Proceedings of the National Academy of Sciences of the United States of America |
B Bai, CM Hales, PC Chen, Y Gozal, EB Dammer, JJ Fritz, X Wang, Q Xia, DM Duong, C Street, G Cantero, D Cheng, DR Jones, Z Wu, Y Li, I Diner, CJ Heilman, HD Rees, H Wu, L Lin, KE Szulwach, M Gearing, EJ Mufson, DA Bennett, TJ Montine, NT Seyfried, TS Wingo, YE Sun, P Jin, J Hanfelt, DM Willcock, A Levey, JJ Lah, J Peng | 10/08/2013 |