Joseph Shelton, MD

Role

Radiation Oncology
Specialty

Bladder Cancer Kidney (Renal) Cancer Lung Cancer Prostate Cancer Testicular Cancer Uterine Cancer
Research Program

Discovery and Developmental Therapeutics
Practicing Since

2011

Call 404-686-2391

Background

A board certified radiation oncologist, Joseph (Jay) Shelton, MD, specializes in the treatment of kidney cancer, lung cancer, prostate cancer, testicular cancer, and uterine cancer at the Loughlin Radiation Oncology Center at Grady. Dr. Shelton is an associate professor in the Department of Radiation Oncology at Emory University School of Medicine.

Dr. Shelton received his MD from the University of North Carolina. He did his internship at the Emory University School of Medicine and completed his residency at the Department of Radiation Oncology, Emory University School of Medicine.

Dr. Shelton's research areas include gynecologic cancers, specifically of the cervix and uterus looking retrospectively at outcomes; and genitourinary cancers, specifically phase II initiated bladder study.

Publications
Research Gate

Titles & Roles

Associate Professor, Department of Radiation Oncology

Emory University School of Medicine
Medical Director, Loughlin Radiation Oncology Center

Grady Memorial Hospital

Education & Training

Education

Residency, Radiation Oncology, 2011
Emory University School of Medicine
Internship, RNFA, Radiation Oncology, 2007
Emory University School of Medicine
Internship, Radiation Oncology, 2007
Emory University School of Medicine
Medical Education, MD, 2006
UNC-Chapel Hill SOM
Medical Education, 2006
UNC-Chapel Hill SOM

Board Certifications

Radiation Oncology
American Board of Radiology, 2012

Research

Publications

Title/Journal	Authors	Publication Date
Data-Driven Volumetric Computed Tomography Image Generation From Surface Structures Using a Patient-Specific Deep Leaning Model. International journal of radiation oncology, biology, physics	S Pan, CW Chang, Z Tian, T Wang, M Axente, J Shelton, T Liu, J Roper, X Yang	12/06/2024
CBCT-based synthetic CT image generation using a diffusion model for CBCT-guided lung radiotherapy. Medical physics	X Chen, RLJ Qiu, J Peng, JW Shelton, CW Chang, X Yang, AH Kesarwala	11/01/2024
Tailoring language for genitourinary function in patients with newly diagnosed prostate cancer to facilitate discussions in diverse populations and overcome health literacy barriers. Cancer	KL Kilbridge, D Patil, CP Filson, JW Shelton, SW Thomson, CH Rosenbaum, EC Rothmann, W Martin-Doyle, QD Trinh, VM Narayan, VA Master	10/15/2024
Using a patient-specific diffusion model to generate CBCT-based synthetic CTs for CBCT-guided adaptive radiotherapy. Medical physics	X Chen, RLJ Qiu, T Wang, CW Chang, X Chen, JW Shelton, AH Kesarwala, X Yang	10/14/2024
Impact of Rectal Spacer on Toxicity Reduction in Men Treated With Proton Versus Photon Therapy. International journal of particle therapy	VR Dhere, S Goyal, J Zhou, NT Sebastian, AB Patel, S Hanasoge, PR Patel, J Shelton, KD Godette, BW Hershatter, AB Jani, SA Patel	09/01/2024
Impact of androgen deprivation therapy in patients with unfavorable intermediate-risk prostate cancer receiving brachytherapy-based dose-escalated radiation therapy. Journal of contemporary brachytherapy	NT Sebastian, S Goyal, Y Liu, V Dhere, AB Jani, B Hershatter, PR Patel, JW Shelton, S Hanasoge, KD Godette, SA Patel	08/01/2024
MRI-based prostate cancer classification using 3D efficient capsule network. Medical physics	Y Li, J Wynne, J Wang, J Roper, CW Chang, AB Patel, J Shelton, T Liu, H Mao, X Yang	07/01/2024
Patterns of Undertreatment and Overtreatment in Adjuvant Radiotherapy for Early-Stage Endometrial Cancer Based on Molecular Classification. JAMA oncology	O Ciobanu, Y He, AR Martin, JS Remick, JW Shelton, TY Eng, DC Qian	05/01/2024
Implementation of a Novel Chart Rounds Application to Facilitate Peer Review in a Virtual Academic Environment. Advances in radiation oncology	N Ali, E Schreibmann, O Kayode, A Patel, P Patel, D Qian, N McCall, J Lorenz, KA Higgins, J Bradley, S Brown, J Shelton	03/01/2024
Biochemical Relapse-Free Survival in Postprostatectomy Patients Receiving 18F-Fluciclovine-Guided Prostate Bed-Only Radiation: Post Hoc Analysis of a Prospective Randomized Trial. Practical radiation oncology	VR Dhere, DM Schuster, S Goyal, E Schreibmann, BW Hershatter, SA Patel, JW Shelton, S Hanasoge, PR Patel, NT Sebastian, OA Adediran, IO Lawal, AB Jani	01/01/2024
Safety and efficacy of durvalumab after concurrent chemoradiation in Black patients with locally advanced non-small cell lung cancer. Cancer	NS McCall, JR Janopaul-Naylor, HS McGinnis, AH Kesarwala, S Tian, WA Stokes, JW Shelton, CE Steuer, JW Carlisle, TA Leal, SS Ramalingam, JD Bradley, KA Higgins	12/01/2023
Associations of the gut microbiome with psychoneurological symptom cluster in women with gynecologic cancers: a longitudinal study. Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer	ZA Barandouzi, T Eng, J Shelton, N Khanna, I Scott, R Meador, DW Bruner	10/11/2023
Association of Radiation Facility Volume with Overall Survival in Patients with Very High-Risk Prostate Cancer Treated with Radiation and Androgen Deprivation Therapy. International journal of radiation oncology, biology, physics	N Sebastian, S Goyal, Y Liu, PR Patel, S Hanasoge, VR Dhere, JW Shelton, KD Godette, A Jani, B Hershatter, B Fischer-Valuck, SA Patel	10/01/2023
Biochemical Relapse-Free Survival in Post-Prostatectomy Patients Receiving ¹⁸F-Fluciclovine-Guided Prostate Bed Only Radiation: Post-Hoc Analysis of a Prospective Randomized Trial. International journal of radiation oncology, biology, physics	VR Dhere, DM Schuster, S Goyal, E Schreibmann, B Hershatter, SA Patel, JW Shelton, S Hanasoge, PR Patel, N Sebastian, IO Lawal, A Jani	10/01/2023
Single Institution Experience of the Effect of Adjuvant Radiation on Outcomes for Patients with Uterine Carcinosarcoma. International journal of radiation oncology, biology, physics	R Tobillo, H Grace, KS Martin, N Ali, ABP Jr, PR Patel, JW Shelton, JS Remick, TY Eng	10/01/2023
Radiation Facility Volume and Survival for Men With Very High-Risk Prostate Cancer Treated with Radiation and Androgen Deprivation Therapy. JAMA network open	N Sebastian, S Goyal, Y Liu, JR Janopaul-Naylor, PR Patel, VR Dhere, S Hanasoge, JW Shelton, KD Godette, AB Jani, B Hershatter, B Fischer-Valuck, SA Patel	08/01/2023
2D medical image synthesis using transformer-based denoising diffusion probabilistic model. Physics in medicine and biology	S Pan, T Wang, RLJ Qiu, M Axente, CW Chang, J Peng, AB Patel, J Shelton, SA Patel, J Roper, X Yang	05/05/2023
Data-Driven Volumetric Image Generation from Surface Structures using a Patient-Specific Deep Leaning Model. ArXiv	S Pan, CW Chang, M Axente, T Wang, J Shelton, T Liu, J Roper, X Yang	05/02/2023
Impact of 18 F-Fluciclovine PET/CT Findings on Failure-Free Survival in Biochemical Recurrence of Prostate Cancer Following Salvage Radiation Therapy. Clinical nuclear medicine	IO Lawal, C Marcus, DM Schuster, S Goyal, OA Adediran, VR Dhere, SS Joshi, OA Abiodun-Ojo, VA Master, PR Patel, B Fielder, M Goodman, JW Shelton, O Kucuk, B Hershatter, RK Halkar, AB Jani	04/01/2023
Differences in Failure-Free Survival After Salvage Radiotherapy Guided by Conventional Imaging Versus ¹⁸F-Fluciclovine PET/CT in Postprostatectomy Patients: A Post Hoc Substratification Analysis of the EMPIRE-1 Trial. Journal of nuclear medicine : official publication, Society of Nuclear Medicine	IO Lawal, AB Jani, OA Adediran, S Goyal, OA Abiodun-Ojo, VR Dhere, CV Marcus, SS Joshi, VA Master, PR Patel, M Goodman, JW Shelton, O Kucuk, B Hershatter, B Fielder, RK Halkar, DM Schuster	04/01/2023
Associations Between Social Determinants of Health and Psychoneurologic Symptom Clusters in Women With Gynecologic Cancers: A Longitudinal Study. Oncology nursing forum	ZA Barandouzi, J Bai, TY Eng, P Patel, J Shelton, N Khanna, I Scott, J Remick, R Meador, D Watkins Bruner	02/17/2023
Incidence and predictors of toxicity in the management of vulvar squamous cell carcinoma treated with radiation therapy. Gynecologic oncology reports	NS McCall, TY Eng, JW Shelton, S Hanasoge, PR Patel, AB Patel, AA McCook-Veal, JM Switchenko, TE Cole, N Khanna, CH Han, AN Gordon, KD Starbuck, JS Remick	12/01/2022
Impact of radiation dose to the immune cells in unresectable or stage III non-small cell lung cancer in the durvalumab era. Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology	NS McCall, HS McGinnis, JR Janopaul-Naylor, AH Kesarwala, S Tian, WA Stokes, JW Shelton, CE Steuer, JW Carlisle, T Leal, SS Ramalingam, JD Bradley, KA Higgins	09/01/2022
Randomized Trial of Conventional Versus Conventional Plus Fluciclovine (¹⁸F) Positron Emission Tomography/Computed Tomography-Guided Postprostatectomy Radiation Therapy for Prostate Cancer: Volumetric and Patient-Reported Analyses of Toxic Effects. International journal of radiation oncology, biology, physics	VR Dhere, DM Schuster, S Goyal, E Schreibmann, BW Hershatter, PJ Rossi, JW Shelton, PR Patel, AB Jani	08/01/2022
Definitive intensity modulated proton re-irradiation for lung cancer in the immunotherapy era. Frontiers in oncology	JR Janopaul-Naylor, Y Cao, NS McCall, JM Switchenko, S Tian, H Chen, WA Stokes, AH Kesarwala, MW McDonald, JW Shelton, JD Bradley, KA Higgins	01/01/2022
Bone Marrow Suppression during Postoperative Radiation for Bladder Cancer and Comparative Benefit of Proton Therapy-Phase 2 Trial Secondary Analysis. International journal of particle therapy	RH Press, JW Shelton, C Zhang, Q Dang, S Tian, T Shu, CS Seldon, S Hasan, AB Jani, J Zhou, MW McDonald	01/01/2022
Deep learning-based thoracic CBCT correction with histogram matching. Biomedical physics & engineering express	RLJ Qiu, Y Lei, J Shelton, K Higgins, JD Bradley, WJ Curran, T Liu, AH Kesarwala, X Yang	10/29/2021
Small-Cell Carcinoma of the Prostate: Report of Outcomes of Localized Disease Using the National Cancer Database. Clinical genitourinary cancer	KM Xu, Y Liu, TW Gillespie, AO Osunkoya, B Carthon, MA Bilen, CP Filson, K Ogan, PR Patel, JW Shelton, O Kucuk, S Joshi, AB Jani	08/01/2021
Overall Survival After Treatment of Localized Prostate Cancer With Proton Beam Therapy, External-Beam Photon Therapy, or Brachytherapy. Clinical genitourinary cancer	Y Liu, SA Patel, AB Jani, TW Gillespie, PR Patel, KD Godette, BW Hershatter, JW Shelton, MW McDonald	06/01/2021
¹⁸F-fluciclovine-PET/CT imaging versus conventional imaging alone to guide postprostatectomy salvage radiotherapy for prostate cancer (EMPIRE-1): a single centre, open-label, phase 2/3 randomised controlled trial. Lancet (London, England)	AB Jani, E Schreibmann, S Goyal, R Halkar, B Hershatter, PJ Rossi, JW Shelton, PR Patel, KM Xu, M Goodman, VA Master, SS Joshi, O Kucuk, BC Carthon, MA Bilen, OA Abiodun-Ojo, AA Akintayo, VR Dhere, DM Schuster	05/22/2021
Comparisons of Depression, Sexual Function, and Quality of Life Between Women With Gynecological Cancers and Race-Matched Healthy Controls. Cancer nursing	J Bai, SM Belcher, R Meador, G Daniel, J Shelton, P Patel, M Dolan, J Arluck, N Khanna, I Horowitz, T Liu, D Watkins Bruner	03/01/2021
Influence of Timing Between Androgen Deprivation Therapy and External Beam Radiation Therapy in Patients With Localized, High-Risk Prostate Cancer. Advances in radiation oncology	NS McCall, Y Liu, SA Patel, B Hershatter, D Moghanaki, KD Godette, S Hanasoge, P Patel, BW Fischer-Valuck, JW Shelton, AB Jani	01/01/2021
Bladder preserving chemoradiotherapy compared to surgery for variants of urothelial carcinoma and other tumors types involving the bladder: An analysis of the National Cancer Database. Clinical and translational radiation oncology	JR Janopaul-Naylor, J Zhong, Y Liu, C Zhang, AO Osunkoya, SS Joshi, MA Bilen, B Carthon, O Kucuk, LM Hartsell, J Shelton, AB Jani	01/01/2021
Changes in the Vaginal Microbiome and Associated Toxicities Following Radiation Therapy for Gynecologic Cancers. Frontiers in cellular and infection microbiology	D Tsementzi, R Meador, T Eng, P Patel, J Shelton, J Arluck, I Scott, M Dolan, N Khanna, KT Konstantinidis, DW Bruner	01/01/2021
Virtual Away Rotations Increase Access to Radiation Oncology. Practical radiation oncology	J Janopaul-Naylor, D Qian, M Khan, S Brown, J Lin, Y Syed, A Schlafstein, N Ali, J Shelton, J Bradley, P Patel	01/01/2021
Initial Report of a Randomized Trial Comparing Conventional- vs Conventional plus Fluciclovine (¹⁸F) PET/CT Imaging-Guided Post-Prostatectomy Radiotherapy for Prostate Cancer. International journal of radiation oncology, biology, physics	A Jani, E Schreibmann, S Goyal, H Raghuveer, B Hershatter, PJ Rossi, JW Shelton, PR Patel, KM Xu, M Goodman, V Master, SS Joshi, O Kucuk, B Carthon, MA Bilen, S Cooper, B Fielder, O Abiodun-Ojo, VR Dhere, DM Schuster	12/01/2020
Analysis of Radiation Facility Volume and Survival in Men With Lymph Node-Positive Prostate Cancer Treated With Radiation and Androgen Deprivation Therapy. JAMA network open	SA Patel, S Goyal, Y Liu, D Moghanaki, PR Patel, S Hanasoge, VR Dhere, JW Shelton, KD Godette, AB Jani, B Hershatter, BW Fischer-Valuck	12/01/2020
Lung Stereotactic Body Radiation Therapy and Concurrent Immunotherapy: A Multicenter Safety and Toxicity Analysis. International journal of radiation oncology, biology, physics	S Tian, JM Switchenko, ZS Buchwald, PR Patel, JW Shelton, SE Kahn, RN Pillai, CE Steuer, TK Owonikoko, M Behera, WJ Curran, KA Higgins	09/01/2020
Comparison of vaginal microbiota in gynecologic cancer patients pre- and post-radiation therapy and healthy women. Cancer medicine	D Tsementzi, A Pena-Gonzalez, J Bai, YJ Hu, P Patel, J Shelton, M Dolan, J Arluck, N Khanna, L Conrad, I Scott, TY Eng, KT Konstantinidis, DW Bruner	06/01/2020
Human Mesenchymal glioblastomas are characterized by an increased immune cell presence compared to Proneural and Classical tumors. Oncoimmunology	I Kaffes, F Szulzewsky, Z Chen, CJ Herting, B Gabanic, JE Velázquez Vega, J Shelton, JM Switchenko, JL Ross, LF McSwain, JT Huse, B Westermark, S Nelander, K Forsberg-Nilsson, L Uhrbom, NP Maturi, PJ Cimino, EC Holland, H Kettenmann, CW Brennan, DJ Brat, D Hambardzumyan	01/01/2019
Health care disparities among octogenarians and nonagenarians with stage III lung cancer. Cancer	RJ Cassidy, X Zhang, JM Switchenko, PR Patel, JW Shelton, S Tian, RH Nanda, CE Steuer, RN Pillai, TK Owonikoko, SS Ramalingam, FG Fernandez, SD Force, TW Gillespie, WJ Curran, KA Higgins	02/15/2018
Concomitant Chemotherapy and Radiotherapy with SBRT Boost for Unresectable Stage III Non-Small Cell Lung Cancer: A Phase I Study. Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer	KA Higgins, RN Pillai, Z Chen, S Tian, C Zhang, P Patel, S Pakkala, J Shelton, SD Force, FG Fernandez, CE Steuer, TK Owonikoko, SS Ramalingam, JD Bradley, WJ Curran	11/01/2017
Next-generation sequencing and clinical outcomes of patients with lung adenocarcinoma treated with stereotactic body radiotherapy. Cancer	RJ Cassidy, X Zhang, PR Patel, JW Shelton, CE Escott, GL Sica, MR Rossi, CE Hill, CE Steuer, RN Pillai, SS Ramalingam, TK Owonikoko, M Behera, SD Force, FG Fernandez, WJ Curran, KA Higgins	10/01/2017
Impact of ¹⁸F-Fluciclovine PET on Target Volume Definition for Postprostatectomy Salvage Radiotherapy: Initial Findings from a Randomized Trial. Journal of nuclear medicine : official publication, Society of Nuclear Medicine	AB Jani, E Schreibmann, PJ Rossi, J Shelton, K Godette, P Nieh, VA Master, O Kucuk, M Goodman, R Halkar, S Cooper, Z Chen, DM Schuster	03/01/2017
Image Guided Planning for Prostate Carcinomas With Incorporation of Anti-3-[18F]FACBC (Fluciclovine) Positron Emission Tomography: Workflow and Initial Findings From a Randomized Trial. International journal of radiation oncology, biology, physics	E Schreibmann, DM Schuster, PJ Rossi, J Shelton, S Cooper, AB Jani	09/01/2016
Anatomic structure-based deformable image registration of brachytherapy implants in the treatment of locally advanced cervix cancer. Brachytherapy	JM Ryckman, JW Shelton, AF Waller, E Schreibmann, K Latifi, R Diaz	01/01/2016
Radiotherapy patterns of care in gastric adenocarcinoma: a single institution experience. Journal of gastrointestinal oncology	J Cheng, MH Squires, JL Mikell, SB Fisher, CA Staley, DA Kooby, BF El-Rayes, WJ Curran, WA Hall, LE Colbert, JW Shelton, SK Maithel, J Landry, DS Yu	06/01/2015
Comparison of image-guided radiotherapy technologies for prostate cancer. American journal of clinical oncology	S Das, T Liu, AB Jani, P Rossi, J Shelton, Z Shi, MK Khan	12/01/2014
Prognostic factors for overall survival after radiosurgery for brain metastases from melanoma. American journal of clinical oncology	DM Marcus, M Lowe, MK Khan, DH Lawson, IR Crocker, JW Shelton, A Melton, N Maynard, KA Delman, GW Carlson, M Rizzo	12/01/2014
Low CHD5 expression activates the DNA damage response and predicts poor outcome in patients undergoing adjuvant therapy for resected pancreatic cancer. Oncogene	WA Hall, AV Petrova, LE Colbert, CW Hardy, SB Fisher, B Saka, JW Shelton, MD Warren, BG Pantazides, K Gandhi, J Kowalski, DA Kooby, BF El-Rayes, CA Staley, N Volkan Adsay, WJ Curran, JC Landry, SK Maithel, DS Yu	11/20/2014
CHD7 expression predicts survival outcomes in patients with resected pancreatic cancer. Cancer research	LE Colbert, AV Petrova, SB Fisher, BG Pantazides, MZ Madden, CW Hardy, MD Warren, Y Pan, GP Nagaraju, EA Liu, B Saka, WA Hall, JW Shelton, K Gandhi, R Pauly, J Kowalski, DA Kooby, BF El-Rayes, CA Staley, NV Adsay, WJ Curran, JC Landry, SK Maithel, DS Yu	05/15/2014
3D Ultrasound Nakagami Imaging for Radiation-Induced Vaginal Fibrosis. Proceedings of SPIE--the International Society for Optical Engineering	X Yang, P Rossi, J Shelton, D Bruner, S Tridandapani, T Liu	02/01/2014
Pronecrotic mixed lineage kinase domain-like protein expression is a prognostic biomarker in patients with early-stage resected pancreatic adenocarcinoma. Cancer	LE Colbert, SB Fisher, CW Hardy, WA Hall, B Saka, JW Shelton, AV Petrova, MD Warren, BG Pantazides, K Gandhi, J Kowalski, DA Kooby, BF El-Rayes, CA Staley, NV Adsay, WJ Curran, JC Landry, SK Maithel, DS Yu	09/01/2013
In vitro and in vivo enhancement of chemoradiation using the oral PARP inhibitor ABT-888 in colorectal cancer cells. International journal of radiation oncology, biology, physics	JW Shelton, TV Waxweiler, J Landry, H Gao, Y Xu, L Wang, B El-Rayes, HK Shu	07/01/2013
Noninvasive evaluation of vaginal fibrosis following radiotherapy for gynecologic malignancies: a feasibility study with ultrasound B-mode and Nakagami parameter imaging. Medical physics	X Yang, P Rossi, DW Bruner, S Tridandapani, J Shelton, T Liu	02/01/2013
Clinically Significant Difference in Prostate Localization Using Daily Cone Beam CT (CBCT) and Electromagnetic Transponders. Practical radiation oncology	MK Khan, S Das, T Ogunleye, AB Jani, P Rossi, J Shelton, T Liu	01/01/2013
Reduced acute toxicity associated with the use of volumetric modulated arc therapy for the treatment of adenocarcinoma of the prostate. Practical radiation oncology	WA Hall, L Colbert, D Nickleach, J Shelton, DM Marcus, J Switchenko, PJ Rossi, K Godette, S Cooper, AB Jani	01/01/2013
Observations on prostate intrafraction motion and the effect of reduced treatment time using volumetric modulated arc therapy. Practical radiation oncology	J Shelton, PJ Rossi, H Chen, Y Liu, VA Master, AB Jani	01/01/2011

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