Lily Yang, MD, PhD
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Research Program
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Phone Number
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Email Address
Biography
Lily Yang, MD, PhD is a professor of surgery and radiology and a prominent researcher. Dr. Yang's research experiences include tumor immunology, cancer stem cells, cancer gene therapy, apoptosis resistance, molecular targeted cancer therapy, nanoparticle imaging probes and theranostic nanoparticles for targeted cancer therapy and imaging. Dr. Yang is a member of the Discovery and Developmental Therapeutics Research Program at Winship Cancer Institute. Dr. Yang received her medical training in China at West China University of Medical Sciences and at the Chinese Academy of Preventive Medicine. She received her PhD in molecular and cellular biology at Brown University. She had postdoctoral trainings in the Gene Therapy Laboratories at University of Southern California and in the Department of Genetics and Molecular Medicine Center at Emory University.Education
Titles & Roles
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Professor, Surgery, and Radiology and Imaging SciencesEmory University School of Medicine
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Nancy Panoz Chair of Surgery in Cancer ResearchEmory University School of Medicine
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Director, Surgical Oncology Nanomedicine Research LabEmory University School of Medicine
Professional Memberships
Dr. Yang holds professional memberships with the American Association for Cancer Research, American Society of Nanomedicine and National Cancer Institute Alliance for Nanotechnology in Cancer.
Research
Dr. Yang's research projects focus on the development of novel cancer nanotechnologies and imaging methods to address the major challenges in clinical oncology of early cancer detection, targeted drug delivery, overcoming drug resistance, assessment of therapeutic response using non-invasive imaging, and image-guided surgery.
Recently, Dr. Yang and Huabei Jiang, PhD, of the University of Florida, received a multiple PI R01 grant from the National Institute of Biomedical Imaging and Bioengineering of the NIH. The grant will fund a four-year project to develop and test a multimodal imaging system and targeted nanoprobes for image-guided treatment of breast cancer. The study is a response to chemotherapy being largely ineffective for over 60% of patients with triple negative breast cancer.
Grants
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Publications
Dr. Yang is a member of the editorial boards of a variety of scientific journals, such as Apoptosis, Nanomedicine: Nanotechnology, Biology and Medicine, Theranostics, Breast Cancer-Targets and Therapy, American Journal of Nuclear Medicine, and Molecular Imaging. She has served as a scientist reviewer for multiple NIH study sections, the Breast Cancer Research Program of the Department of Defense, the National Science Foundation, and the California Breast Cancer Research Program as well as many other national and international funding agents.
Title/Journal Authors Publication Date Muc16CD is a novel CAR T cell target antigen for the treatment of pancreatic cancer.
Molecular therapy. Oncology
HK Lin, DA Blake, T Liu, R Freeman, GB Lesinski, L Yang, S Rafiq 12/19/2024 Nanoscale
AM Thamizhchelvan, H Ma, T Wu, D Nguyen, J Padelford, TJ Whitworth, Y Li, L Yang, H Mao 11/28/2024 Nanoscale
K Wells, T Liu, L Zhu, L Yang 10/03/2024 The magic of small-molecule drugs during ex vivo expansion in adoptive cell therapy.
Frontiers in immunology
H Zhang, T Passang, S Ravindranathan, R Bommireddy, MR Jajja, L Yang, P Selvaraj, CM Paulos, EK Waller 01/01/2023 Cancer gene therapy
H Yang, S Tan, J Qiao, Y Xu, Z Gui, Y Meng, B Dong, G Peng, OY Ibhagui, W Qian, J Lu, Z Li, G Wang, J Lai, L Yang, HE Grossniklaus, JJ Yang 12/01/2022 ACS nano
L Zhu, Y Zhao, T Liu, M Chen, WP Qian, B Jiang, BG Barwick, L Zhang, TM Styblo, X Li, L Yang 11/22/2022 Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology
L Zhu, H Mao, L Yang 07/01/2022 Claisened Hexafluoro Inhibits Metastatic Spreading of Amoeboid Melanoma Cells.
Cancers
A Leo, E Pranzini, L Pietrovito, E Pardella, M Parri, P Cirri, G Bruno, M Calvani, S Peppicelli, E Torre, M Sasaki, L Yang, L Zhu, P Chiarugi, G Raugei, JL Arbiser, ML Taddei 07/15/2021 Nature communications
B Zhang, Y Li, Q Wu, L Xie, B Barwick, C Fu, X Li, D Wu, S Xia, J Chen, WP Qian, L Yang, AO Osunkoya, L Boise, PM Vertino, Y Zhao, M Li, HR Chen, J Kowalski, O Kucuk, W Zhou, JT Dong 03/17/2021 Oncotarget
BF Peake, SM Eze, L Yang, RC Castellino, R Nahta 11/03/2020 Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology
M Xie, Y Xu, J Huang, Y Li, L Wang, L Yang, H Mao 11/01/2020 ACS applied bio materials
Y Li, H Wu, B Ji, W Qian, S Xia, L Wang, Y Xu, J Chen, L Yang, H Mao 07/20/2020 International journal of radiation biology
S Tang, Z Li, L Yang, L Shen, Y Wang 04/01/2020 Fan-shaped scanning approach for miniaturized photoacoustic tomography.
Journal of biophotonics
H Yang, T Shan, L Yang, H Jiang 02/01/2020 Theranostics
Y Xu, H Wu, J Huang, W Qian, DE Martinson, B Ji, Y Li, YA Wang, L Yang, H Mao 01/01/2020 Physics in medicine and biology
H Yang, D Wang, T Shan, X Dai, H Xie, L Yang, H Jiang 06/20/2019 Cancer research
I El Ayachi, I Fatima, P Wend, JA Alva-Ornelas, S Runke, WL Kuenzinger, J Silva, W Silva, JK Gray, S Lehr, HC Barch, RI Krutilina, AC White, R Cardiff, LD Yee, L Yang, RM O'Regan, WE Lowry, TN Seagroves, V Seewaldt, SA Krum, GA Miranda-Carboni 03/01/2019 Palladium based nanoparticles for the treatment of advanced melanoma.
Scientific reports
J Elsey, JA Bubley, L Zhu, S Rao, M Sasaki, BP Pollack, L Yang, JL Arbiser 03/01/2019 Theranostics
M Satpathy, L Wang, RJ Zielinski, W Qian, YA Wang, AM Mohs, BA Kairdolf, X Ji, J Capala, M Lipowska, S Nie, H Mao, L Yang 01/01/2019 Inhibition of breast cancer metastasis to the lungs with UBS109.
Oncotarget
M Shoji, WP Qian, GP Nagaraju, DJ Brat, D Pessolano, R Luzietti, S Chennamadhavuni, M Yamaguchi, L Yang, DC Liotta 11/16/2018 BAI1 Suppresses Medulloblastoma Formation by Protecting p53 from Mdm2-Mediated Degradation.
Cancer cell
D Zhu, S Osuka, Z Zhang, ZR Reichert, L Yang, Y Kanemura, Y Jiang, S You, H Zhang, NS Devi, D Bhattacharya, S Takano, GY Gillespie, T Macdonald, C Tan, R Nishikawa, WG Nelson, JJ Olson, EG Van Meir 06/11/2018 Nanotechnology Strategies To Advance Outcomes in Clinical Cancer Care.
ACS nano
CM Hartshorn, MS Bradbury, GM Lanza, AE Nel, J Rao, AZ Wang, UB Wiesner, L Yang, P Grodzinski 01/23/2018 Journal of materials chemistry. B
Y Li, Y Xu, CC Fleischer, J Huang, R Lin, L Yang, H Mao 01/07/2018 Biomaterials
J Miller-Kleinhenz, X Guo, W Qian, H Zhou, EN Bozeman, L Zhu, X Ji, YA Wang, T Styblo, R O'Regan, H Mao, L Yang 01/01/2018 Cancer
A Belalcazar, WL Shaib, MR Farren, C Zhang, Z Chen, L Yang, GB Lesinski, BF El-Rayes, GP Nagaraju 12/15/2017 Targeted Molecular Imaging of Pancreatic Cancer with a Miniature Endoscope.
Applied sciences (Basel, Switzerland)
X Dai, W Qian, H Yang, L Yang, H Jiang 12/01/2017 Oncotarget
BF Peake, SM Eze, L Yang, RC Castellino, R Nahta 11/07/2017 ACS nano
L Wang, J Huang, H Chen, H Wu, Y Xu, Y Li, H Yi, YA Wang, L Yang, H Mao 05/23/2017 Cancer letters
L Zhu, C Staley, D Kooby, B El-Rays, H Mao, L Yang 03/01/2017 Nanoparticle-linked antagonist for leptin signaling inhibition in breast cancer.
World journal of clinical oncology
T Harmon, A Harbuzariu, V Lanier, CC Lipsey, W Kirlin, L Yang, RR Gonzalez-Perez 02/10/2017 Nanomedicine (London, England)
L Zhu, Z Zhou, H Mao, L Yang 01/01/2017 Theranostics
N Gao, EN Bozeman, W Qian, L Wang, H Chen, M Lipowska, CA Staley, YA Wang, H Mao, L Yang 01/01/2017 Medical physics
H Xie, W Cai, L Yang, H Mao, X Tang 11/01/2016 Advanced functional materials
J Huang, Y Li, A Orza, Q Lu, P Guo, L Wang, L Yang, H Mao 06/14/2016 Proceedings of SPIE--the International Society for Optical Engineering
H Zhou, W Qian, FM Uckun, Z Zhou, L Wang, A Wang, H Mao, L Yang 04/17/2016 ACS applied materials & interfaces
G Wang, F Zhang, R Tian, L Zhang, G Fu, L Yang, L Zhu 03/02/2016 Biomaterials
JM Patel, VF Vartabedian, EN Bozeman, BE Caoyonan, S Srivatsan, CD Pack, P Dey, MJ D'Souza, L Yang, P Selvaraj 01/01/2016 International journal of nanomedicine
J Huang, W Qian, L Wang, H Wu, H Zhou, AY Wang, H Chen, L Yang, H Mao 01/01/2016 Medical physics
A Orza, Y Yang, T Feng, X Wang, H Wu, Y Li, L Yang, X Tang, H Mao 01/01/2016 Targeted Delivery with Imaging Assessment of siRNA Expressing Nanocassettes into Cancer.
Methods in molecular biology (Clifton, N.J.)
W Chen, L Yang 01/01/2016 Journal of materials chemistry. B
Y Li, R Lin, L Wang, J Huang, H Wu, G Cheng, Z Zhou, T MacDonald, L Yang, H Mao 05/07/2015 International journal of nanomedicine
Y Chen, L Gong, N Gao, J Liao, J Sun, Y Wang, L Wang, P Zhu, Q Fan, YA Wang, W Zeng, H Mao, L Yang, F Gao 01/01/2015 Optical imaging of ovarian cancer using HER-2 affibody conjugated nanoparticles.
Methods in molecular biology (Clifton, N.J.)
M Satpathy, R Zielinski, I Lyakhov, L Yang 01/01/2015 Theranostics
E Yang, W Qian, Z Cao, L Wang, EN Bozeman, C Ward, B Yang, P Selvaraj, M Lipowska, YA Wang, H Mao, L Yang 01/01/2015 Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology
JM Miller-Kleinhenz, EN Bozeman, L Yang 01/01/2015 Photoacoustic and fluorescence image-guided surgery using a multifunctional targeted nanoprobe.
Annals of surgical oncology
L Xi, G Zhou, N Gao, L Yang, DA Gonzalo, SJ Hughes, H Jiang 05/01/2014 Nanomedicine : nanotechnology, biology, and medicine
L Xi, M Satpathy, Q Zhao, W Qian, L Yang, H Jiang 04/01/2014 Small (Weinheim an der Bergstrasse, Germany)
M Satpathy, L Wang, R Zielinski, W Qian, M Lipowska, J Capala, GY Lee, H Xu, YA Wang, H Mao, L Yang 02/12/2014 Journal of materials chemistry. B
J Huang, L Wang, X Zhong, Y Li, L Yang, H Mao 01/01/2014 Nanoparticles for cancer imaging: The good, the bad, and the promise.
Nano today
S Chapman, M Dobrovolskaia, K Farahani, A Goodwin, A Joshi, H Lee, T Meade, M Pomper, K Ptak, J Rao, R Singh, S Sridhar, S Stern, A Wang, JB Weaver, G Woloschak, L Yang 10/01/2013 Journal of biomaterials applications
Z Zhou, H Chen, M Lipowska, L Wang, Q Yu, X Yang, D Tiwari, L Yang, H Mao 07/01/2013 ACS applied materials & interfaces
J Huang, L Wang, R Lin, AY Wang, L Yang, M Kuang, W Qian, H Mao 06/12/2013 Targeted delivery of siRNA-generating DNA nanocassettes using multifunctional nanoparticles.
Small (Weinheim an der Bergstrasse, Germany)
YS Cho, GY Lee, HK Sajja, W Qian, Z Cao, W He, P Karna, X Chen, H Mao, YA Wang, L Yang 06/10/2013 ACS nano
GY Lee, WP Qian, L Wang, YA Wang, CA Staley, M Satpathy, S Nie, H Mao, L Yang 03/26/2013 Biomedical optics express
H Yang, L Xi, S Samuelson, H Xie, L Yang, H Jiang 03/01/2013 International journal of nanomedicine
H Chen, L Wang, Q Yu, W Qian, D Tiwari, H Yi, AY Wang, J Huang, L Yang, H Mao 01/01/2013 Journal of X-ray science and technology
Y Tan, Z Cao, HK Sajja, M Lipowska, YA Wang, L Yang, H Jiang 01/01/2013 uPAR-targeted optical imaging contrasts as theranostic agents for tumor margin detection.
Theranostics
L Yang, HK Sajja, Z Cao, W Qian, L Bender, AI Marcus, M Lipowska, WC Wood, YA Wang 01/01/2013 Theranostics
J Huang, X Zhong, L Wang, L Yang, H Mao 01/01/2012 Biomaterials
L Yang, YS Cho, HK Sajja, P Karna, TJ Yoon, Z Cao 12/12/2011 Combinatorial effects of lapatinib and rapamycin in triple-negative breast cancer cells.
Molecular cancer therapeutics
T Liu, R Yacoub, LD Taliaferro-Smith, SY Sun, TR Graham, R Dolan, C Lobo, M Tighiouart, L Yang, A Adams, RM O'Regan 08/01/2011 Seminars in oncology
CG Hadjipanayis, H Jiang, DW Roberts, L Yang 02/01/2011 Journal of magnetic resonance imaging : JMRI
L Zhang, X Zhong, L Wang, H Chen, YA Wang, J Yeh, L Yang, H Mao 01/01/2011 Nanotechnology, science and applications
L Zhang, H Chen, L Wang, T Liu, J Yeh, G Lu, L Yang, H Mao 12/03/2010 Biomaterials
H Chen, L Wang, J Yeh, X Wu, Z Cao, YA Wang, M Zhang, L Yang, H Mao 07/01/2010 PloS one
J Kauh, S Fan, M Xia, P Yue, L Yang, FR Khuri, SY Sun 04/28/2010 Abundance of a distinct cluster of telomere t-stumps in advanced breast cancer cell line.
Oncology letters
RB Pai, SB Pai, L Yang, HC Joshi 03/01/2010 Current molecular medicine
MQ Smith, CA Staley, DA Kooby, T Styblo, WC Wood, L Yang 11/01/2009 Designing caspase-3 sensors for imaging of apoptosis in living cells.
Chemistry (Weinheim an der Bergstrasse, Germany)
N Chen, Y Huang, L Yang, R Liu, JJ Yang 09/21/2009 Receptor-targeted nanoparticles for in vivo imaging of breast cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research
L Yang, XH Peng, YA Wang, X Wang, Z Cao, C Ni, P Karna, X Zhang, WC Wood, X Gao, S Nie, H Mao 07/15/2009 Gastroenterology
L Yang, H Mao, Z Cao, YA Wang, X Peng, X Wang, HK Sajja, L Wang, H Duan, C Ni, CA Staley, WC Wood, X Gao, S Nie 05/01/2009 Current drug discovery technologies
HK Sajja, MP East, H Mao, YA Wang, S Nie, L Yang 03/01/2009 Small (Weinheim an der Bergstrasse, Germany)
L Yang, H Mao, YA Wang, Z Cao, X Peng, X Wang, H Duan, C Ni, Q Yuan, G Adams, MQ Smith, WC Wood, X Gao, S Nie 02/01/2009 Journal of biomedical nanotechnology
L Yang, Z Cao, HK Sajja, H Mao, L Wang, H Geng, H Xu, T Jiang, WC Wood, S Nie, YA Wang 12/01/2008 The effect of HIF-1alpha siRNA on growth and chemosensitivity of MIA-paca cell line.
Yonsei medical journal
L Yang, WK Kang 04/30/2008 The Journal of investigative dermatology
NS Funa, K Reddy, S Bhandarkar, EV Kurenova, L Yang, WG Cance, M Welsh, JL Arbiser 03/01/2008 Application of nanotechnology in cancer therapy and imaging.
CA: a cancer journal for clinicians
X Wang, L Yang, ZG Chen, DM Shin 01/01/2008 In vivo tumor targeting and spectroscopic detection with surface-enhanced Raman nanoparticle tags.
Nature biotechnology
X Qian, XH Peng, DO Ansari, Q Yin-Goen, GZ Chen, DM Shin, L Yang, AN Young, MD Wang, S Nie 01/01/2008 Quantum dots and multifunctional nanoparticles: new contrast agents for tumor imaging.
Nanomedicine (London, England)
MN Rhyner, AM Smith, X Gao, H Mao, L Yang, S Nie 08/01/2006 In vivo molecular and cellular imaging with quantum dots.
Current opinion in biotechnology
X Gao, L Yang, JA Petros, FF Marshall, JW Simons, S Nie 02/01/2005