Shruti Bhatt, PhD, is an assistant professor in the Department of Hematology and Medical Oncology at Emory University School of Medicine. A cancer biologist, Dr. Bhatt has extensive expertise in studying the biology of leukemia relapse, cell death pathways—particularly apoptosis—and personalizing targeted therapies such as BH3 mimetics.
Dr. Bhatt joined the faculty at Winship Cancer Institute of Emory University in 2025 and is a member of Winship's Discovery and Developmental Therapeutics Research Program. Prior to her arrival, she was a faculty at the National University of Singapore.
Education
Dr. Bhatt earned her PhD in molecular and cellular pharmacology from the University of Miami in Miami, Florida. She also holds an MS in pharmacology and toxicology from Long Island University in New York. She completed her postdoctoral training at Dana-Farber Cancer Institute in Boston, Massachusetts.
Titles & Roles
Assistant Professor, Department of Hematology and Medical Oncology
Emory University School of Medicine
Professional Memberships
American Association for Cancer Research
American Society of Hematology
Research
The Bhatt lab focuses on identifying treatment strategies and the underlying mechanisms of therapy resistance in myeloid malignancies by studying cell death pathways, particularly the mitochondrial pathway of apoptosis. The lab employs a multi-dimensional approach utilizing patient-derived xenograft models, single-cell transcriptomics, lineage tracing, functional profiling including dynamic BH3 profiling, and comprehensive multi-omics analyses to emphasize research goals of:
Identifying the driving forces behind therapy resistance in TP53-mutant myeloid neoplasms.
Modeling the clonal architecture of leukemia relapse by studying drug-tolerant persisters.
Determining the role of the tumor microenvironment in driving leukemia relapse.
Developing functional approaches for predicting response to targeted therapy in a heterogeneous population.
