Huw Davies, PhD
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Research Program
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Email Address

Huw M. L. Davies, PhD, joined the Emory University faculty in 2008 as the Asa Griggs Candler Professor of Organic Chemistry. He is a member of the Discovery and Developmental Therapeutics Research Program at Winship Cancer Institute of Emory University in Atlanta, Georgia. Prior to Emory, he held the positions of UB Distinguished Professor and Larkin Professor of Organic Chemistry at the University at Buffalo, the State University of New York.
Dr. Davies received his BSc degree from University College in Cardiff, Wales, and his PhD from the University of East Anglia. He completed his post-doctoral training at Princeton University.
Dr. Davies' research emphasizes the development of new enantioselective synthetic methods and their applications in total synthesis and drug discovery. His program covers design of chiral catalysts, carbenoid chemistry, development of new synthetic methodology, total synthesis of biologically active natural products and development of chiral therapeutic agents. Many research groups have used his chiral dirhodium catalysts and several of them are commercially available.
Grant Number | Title |
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5R01GM099142-12 | New Directions in Enantioselective C-H Functionalization |
Title/Journal | Authors | Publication Date |
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Organic letters |
B Keen, C Cong, A Castanedo, GHM Davies, RR Knowles, HML Davies | 02/10/2025 |
Molecular Dynamics of the Davies Ambimodal C-H Functionalization/Cope Rearrangement Reaction. The Journal of organic chemistry |
Y Zhang, C Cao, Y She, HML Davies, YF Yang, KN Houk | 12/06/2024 |
Organic process research & development |
U Ryu, D Ly, K Shimabukuro, HML Davies, CW Jones | 11/15/2024 |
Total synthesis of (-)-cylindrocyclophane A facilitated by C-H functionalization. Science (New York, N.Y.) |
AT Bosse, LR Hunt, CA Suarez, TD Casselman, EL Goldstein, AC Wright, H Park, SC Virgil, JQ Yu, BM Stoltz, HML Davies | 11/08/2024 |
ACS medicinal chemistry letters |
WF Tracy, GHM Davies, L Jia, ED Evans, Z Sun, J Buenviaje, G Khambatta, S Yu, L Shi, V Shanmugasundaram, J Moreno, EC Cherney, HML Davies | 09/12/2024 |
Journal of the American Chemical Society |
Z Chen, K Shimabukuro, J Bacsa, DG Musaev, HML Davies | 07/17/2024 |
Journal of the American Chemical Society |
MN Hall, M Lee, TW Root, HML Davies, SS Stahl | 05/22/2024 |
Rhodium(II)-Catalyzed Asymmetric Cyclopropanation and Desymmetrization of [2.2]Paracyclophanes. ACS catalysis |
D Ly, J Bacsa, HML Davies | 05/03/2024 |
Better Together: Catalyzing Innovation in Organic Synthesis via Academic-Industrial Consortia. Organic letters |
J Alcázar, EA Anderson, HML Davies, R Febrian, CB Kelly, T Noël, EA Voight, C Zarate, E Zysman-Colman | 04/12/2024 |
Organic letters |
TH Nguyen, A Navarro, JC Ruble, HML Davies | 04/12/2024 |
The Journal of organic chemistry |
WF Tracy, GHM Davies, LN Grant, JM Ganley, J Moreno, EC Cherney, HML Davies | 04/05/2024 |
Journal of the American Chemical Society |
TH Nguyen, AT Bosse, D Ly, CA Suarez, J Fu, K Shimabukuro, DG Musaev, HML Davies | 03/27/2024 |
ACS catalysis |
Y Naeem, BT Matsuo, HML Davies | 01/05/2024 |
ACS medicinal chemistry letters |
A Rab, X Yang, WF Tracy, JS Hong, D Joshi, C Manfredi, SS Ponnaluri, AA Kolykhalov, M Qui, H Fu, Y Du, HML Davies, EJ Sorscher | 10/12/2023 |
Diruthenium Tetracarboxylate-Catalyzed Enantioselective Cyclopropanation with Aryldiazoacetates. Organometallics |
JK Sailer, JC Sharland, J Bacsa, CF Harris, JF Berry, DG Musaev, HML Davies | 08/14/2023 |
One-Pot Synthesis of Difluorobicyclo[1.1.1]pentanes from α-Allyldiazoacetates. Organic letters |
JC Sharland, HML Davies | 07/21/2023 |
Organic letters |
S Fischer, TH Nguyen, A Ratzenboeck, HML Davies, O Reiser | 06/23/2023 |
Organic letters |
Z Chen, Q Cai, YT Boni, W Liu, J Fu, HML Davies | 06/09/2023 |
Organic letters |
M Lee, HML Davies | 06/09/2023 |
Dirhodium C-H Functionalization of Hole-Transport Materials. The Journal of organic chemistry |
F Saeedifard, Y Naeem, YT Boni, YC Chang, J Zhang, Y Zhang, B Kippelen, S Barlow, HML Davies, SR Marder | 04/07/2023 |
Organic letters |
YT Boni, J Vaitla, HML Davies | 01/13/2023 |
Organic letters |
CJ Bettencourt, T Krainz, S Chow, BT Parr, WF Tracy, PV Bernhardt, HML Davies, CM Williams | 12/23/2022 |
ACS catalysis |
B Wei, JC Sharland, DG Blackmond, DG Musaev, HML Davies | 11/04/2022 |
The Journal of organic chemistry |
RW Kubiak, WF Tracy, JS Alford, HML Davies | 11/04/2022 |
Design, Synthesis, and Evaluation of Extended C4-Symmetric Dirhodium Tetracarboxylate Catalysts. ACS catalysis |
ZJ Garlets, YT Boni, JC Sharland, PR Kirby, J Fu, J Bacsa, HML Davies | 09/02/2022 |
Journal of the American Chemical Society |
YT Boni, RC Cammarota, K Liao, MS Sigman, HML Davies | 08/31/2022 |
Journal of the American Chemical Society |
RC Cammarota, W Liu, J Bacsa, HML Davies, MS Sigman | 02/02/2022 |
A C-H Functionalization Strategy Enables an Enantioselective Formal Synthesis of (-)-Aflatoxin B2. Organic letters |
NA Falcone, AT Bosse, H Park, JQ Yu, HML Davies, EJ Sorensen | 12/17/2021 |
Chemical science |
JC Sharland, B Wei, DJ Hardee, TR Hodges, W Gong, EA Voight, HML Davies | 08/25/2021 |
Organic letters |
B Wei, TA Hatridge, CW Jones, HML Davies | 07/16/2021 |
Angewandte Chemie (International ed. in English) |
TA Hatridge, W Liu, CJ Yoo, HML Davies, CW Jones | 10/26/2020 |
The Journal of organic chemistry |
B Wertz, Z Ren, J Bacsa, DG Musaev, HML Davies | 10/02/2020 |
Rhodium-Stabilized Diarylcarbenes Behaving as Donor/Acceptor Carbenes. ACS catalysis |
M Lee, Z Ren, DG Musaev, HML Davies | 06/05/2020 |
Angewandte Chemie (International ed. in English) |
J Vaitla, YT Boni, HML Davies | 05/04/2020 |
Chemistry (Weinheim an der Bergstrasse, Germany) |
W Liu, T Babl, A Röther, O Reiser, HML Davies | 04/01/2020 |
Rhodium-Catalyzed Enantioselective [4+2] Cycloadditions of Vinylcarbenes with Dienes. Angewandte Chemie (International ed. in English) |
B Zhang, HML Davies | 03/16/2020 |
Donor-Acceptor-Acceptor 1,3-Bisdiazo Compounds: An Exploration of Synthesis and Stepwise Reactivity. Organic letters |
DJ Abrams, HML Davies, EJ Sorensen | 03/06/2020 |
Regio- and Stereoselective Rhodium(II)-Catalyzed C-H Functionalization of Cyclobutanes. Chem |
ZJ Garlets, BD Wertz, W Liu, EA Voight, HML Davies | 01/09/2020 |
C-H Functionalization Approach for the Synthesis of Chiral C2-Symmetric 1,5-Cyclooctadiene Ligands. Organic letters |
B Zhang, MR Hollerbach, SB Blakey, HML Davies | 12/20/2019 |
The Journal of organic chemistry |
HML Davies | 10/18/2019 |
Organic letters |
J Fu, N Wurzer, V Lehner, O Reiser, HML Davies | 08/02/2019 |
Organic letters |
ZJ Garlets, EF Hicks, J Fu, EA Voight, HML Davies | 06/21/2019 |
Dirhodium tetracarboxylates as catalysts for selective intermolecular C-H functionalization. Nature reviews. Chemistry |
HML Davies, K Liao | 06/01/2019 |
Desymmetrization of cyclohexanes by site- and stereoselective C-H functionalization. Nature |
J Fu, Z Ren, J Bacsa, DG Musaev, HML Davies | 12/01/2018 |
New directions in natural product synthesis. Chemical Society reviews |
HML Davies, K Itami, BM Stoltz | 10/29/2018 |
Nature chemistry |
K Liao, YF Yang, Y Li, JN Sanders, KN Houk, DG Musaev, HML Davies | 10/01/2018 |
Journal of the American Chemical Society |
W Liu, Z Ren, AT Bosse, K Liao, EL Goldstein, J Bacsa, DG Musaev, BM Stoltz, HML Davies | 09/26/2018 |
Angewandte Chemie (International ed. in English) |
CJ Yoo, D Rackl, W Liu, CB Hoyt, B Pimentel, RP Lively, HML Davies, CW Jones | 08/20/2018 |
The Journal of organic chemistry |
SM Wilkerson-Hill, BE Haines, DG Musaev, HML Davies | 08/03/2018 |
Organic letters |
RW Kubiak, HML Davies | 07/06/2018 |
Blue light-promoted photolysis of aryldiazoacetates. Chemical science |
ID Jurberg, HML Davies | 06/14/2018 |
Organic letters |
L Fu, K Hoang, C Tortoreto, W Liu, HML Davies | 04/20/2018 |
Organic letters |
ZJ Garlets, HML Davies | 04/20/2018 |
Site-selective and stereoselective functionalization of non-activated tertiary C-H bonds. Nature |
K Liao, TC Pickel, V Boyarskikh, J Bacsa, DG Musaev, HML Davies | 11/30/2017 |
Organic letters |
ID Jurberg, HML Davies | 10/06/2017 |
Collective Approach to Advancing C-H Functionalization. ACS central science |
HML Davies, D Morton | 09/27/2017 |
Organic letters |
V Lehner, HML Davies, O Reiser | 09/15/2017 |
Organic letters |
D Rackl, CJ Yoo, CW Jones, HML Davies | 06/16/2017 |
Organic letters |
L Fu, HM Davies | 04/07/2017 |
Chemistry (Weinheim an der Bergstrasse, Germany) |
L Fu, JD Mighion, EA Voight, HM Davies | 03/08/2017 |
Metal-Free C-H Functionalization of Alkanes by Aryldiazoacetates. Organic letters |
C Tortoreto, D Rackl, HM Davies | 02/17/2017 |
Angewandte Chemie (International ed. in English) |
TA Bedell, GA Hone, D Valette, JQ Yu, HM Davies, EJ Sorensen | 07/11/2016 |
Organic letters |
RW Kubiak, JD Mighion, SM Wilkerson-Hill, JS Alford, T Yoshidomi, HM Davies | 07/01/2016 |
Site-selective and stereoselective functionalization of unactivated C-H bonds. Nature |
K Liao, S Negretti, DG Musaev, J Bacsa, HM Davies | 05/12/2016 |
Rhodium(II)-Catalyzed C-H Functionalization of Electron-Deficient Methyl Groups. Journal of the American Chemical Society |
L Fu, DM Guptill, HM Davies | 05/11/2016 |
Recent Advances in C-H Functionalization. The Journal of organic chemistry |
HM Davies, D Morton | 01/15/2016 |
Tetrahedron |
S Negretti, CM Cohen, JJ Chang, DM Guptill, HML Davies | 09/30/2015 |
Chemical science |
EN Bess, DM Guptill, HML Davies, MS Sigman | 05/01/2015 |
Organic letters |
BT Parr, HM Davies | 02/20/2015 |
Concise syntheses of dictyodendrins A and F by a sequential C-H functionalization strategy. Journal of the American Chemical Society |
AD Yamaguchi, KM Chepiga, J Yamaguchi, K Itami, HM Davies | 01/21/2015 |
Nature communications |
J He, LG Hamann, HM Davies, RE Beckwith | 01/12/2015 |
Journal of the American Chemical Society |
DM Guptill, HM Davies | 12/24/2014 |
Enantioselective synthesis of (-)-maoecrystal V by enantiodetermining C-H functionalization. Journal of the American Chemical Society |
P Lu, A Mailyan, Z Gu, DM Guptill, H Wang, HM Davies, A Zakarian | 12/24/2014 |
Angewandte Chemie (International ed. in English) |
PE Guzmán, Y Lian, HM Davies | 11/24/2014 |
C-H functionalization: collaborative methods to redefine chemical logic. Angewandte Chemie (International ed. in English) |
HM Davies, D Morton | 09/22/2014 |
Organic letters |
JE Spangler, Y Lian, SN Raikar, HM Davies | 09/19/2014 |
Journal of immunology (Baltimore, Md. : 1950) |
DH Davies, S Chun, G Hermanson, JA Tucker, A Jain, R Nakajima, J Pablo, PL Felgner, X Liang | 08/15/2014 |
Nature communications |
BT Parr, HM Davies | 08/01/2014 |
Journal of the American Chemical Society |
JS Alford, HM Davies | 07/23/2014 |
Journal of the American Chemical Society |
C Qin, HM Davies | 07/09/2014 |
Organic letters |
L Fu, H Wang, HM Davies | 06/06/2014 |
Diversity-oriented synthesis as a tool for identifying new modulators of mitosis. Nature communications |
BM Ibbeson, L Laraia, E Alza, CJ O' Connor, YS Tan, HM Davies, G McKenzie, AR Venkitaraman, DR Spring | 01/01/2014 |
Rhodium(II)-catalyzed stereoselective synthesis of allylsilanes. Organic letters |
DM Guptill, CM Cohen, HM Davies | 12/20/2013 |
Silica-immobilized chiral dirhodium(II) catalyst for enantioselective carbenoid reactions. Organic letters |
KM Chepiga, Y Feng, NA Brunelli, CW Jones, HM Davies | 12/20/2013 |
Silver-catalyzed vinylogous fluorination of vinyl diazoacetates. Organic letters |
C Qin, HM Davies | 12/20/2013 |
The impact of his carbenoid chemistry was recently recognized as he was chosen to be the recipient of the 2013 eEROS Reagent of the Year Award. Other recent awards Dr. Davies has received include the American Chemical Society Cope Scholar Award (2005), Fellow of the Royal Society of Chemistry (2007), Fellow of the American Chemical Society (2009), Fellow of the American Association for the Advancement of Science (2012) and Fellow of the National Academy of Inventors (2014).