Steven H. Liang, PhD
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Research Program
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Phone Number
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Email Address
Biography
Steven H. Liang, PhD, is a professor in the Department of Radiology and Imaging Sciences and serves as SOM endowed director of the Radiochemistry, Cyclotron Facility and Radiopharmacy Center for System Imaging at Emory University School of Medicine. Dr. Liang also heads the Emory Positron Emission Tomography (PET) Center.
Dr. Liang is a member of the Discovery and Developmental Therapeutics Research Program at Winship Cancer Institute of Emory University.
Education
Dr. Liang earned his PhD from the University of British Columbia in Vancouver, British Columbia. He completed his postdoctoral training at Harvard University in Cambridge, Massachusetts.
Titles & Roles
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Professor, Department of Radiology and Imaging SciencesEmory University School of Medicine
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SOM Endowed Director, Radiochemistry, Cyclotron Facility and Radiopharmacy Center for System ImagingEmory University School of Medicine
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LeaderEmory Positron Emission Tomography (PET) Center
Professional Memberships
Dr. Liang holds professional memberships with American Chemical Society, Canadian Society of Chemistry, Society of Radiopharmaceutical Sciences, Society of Nuclear Medicine and Molecular Imaging and Sino-American Society of Nuclear Medicine. He is past president of the Radiopharmaceutical Sciences Council, Society of Nuclear Medicine and Molecular Imaging.
Research
Dr. Liang's research interests are centered on the discovery of radioactive drugs including positron emission tomography (PET) and theranostic agents for important yet underexplored biological targets for human disease, and subsequently transition new diagnostics and radiotherapies into clinical use. >>Visit Dr. Liang's research program website.
Publications
Dr. Liang has been published extensively in numerous peer-reviewed scientific journals. He serves on the editorial board of Theranostics and Molecular Imaging and serves as associate editor for American Journal of Nuclear Medicine and Molecular Imaging.
| Title/Journal | Authors | Publication Date |
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European journal of nuclear medicine and molecular imaging |
J Liang, S Weng, J Zhang, S Jiang, W Li, S Li, J Rong, H Liu, H Chen, Z Liu, H Peng, S Yan, R Zhang, SH Liang, L Zhang | 09/01/2025 |
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Molecular Afterglow of Lophine-Based Luminophore and Its Imaging Applications. Angewandte Chemie (International ed. in English) |
J Yang, Y Yang, H Wang, SH Liang, C Ran | 08/25/2025 |
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ACS medicinal chemistry letters |
X Zhou, SH Liang | 08/14/2025 |
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Novel Leucine-Rich Repeat Kinase 2 (LRRK2) Inhibitors for the Treatment of Parkinson's Disease. ACS medicinal chemistry letters |
Z Song, SH Liang | 08/14/2025 |
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Novel Peptides as GIPR/GLP-1R/GCGR Triagonists for Treating Type 2 Diabetes Mellitus. ACS medicinal chemistry letters |
Q Hu, SH Liang | 08/14/2025 |
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Novel Thieno[3,2‑b]Pyridine Derivatives in the Treatment of Huntington's Disease. ACS medicinal chemistry letters |
T Zhao, SH Liang | 08/14/2025 |
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Preparation of Novel PARP1 Inhibitors and Their Use in Cancer Treatment. ACS medicinal chemistry letters |
X Zhou, SH Liang | 08/14/2025 |
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The Development of Inhibitors for NLRP3 Inflammasome. ACS medicinal chemistry letters |
X Zhou, SH Liang | 08/14/2025 |
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Journal of medicinal chemistry |
Z Song, Y Li, K Dahl, Z Sun, J Chen, X Zhou, Y Gao, J Rong, C Zhao, K Yuan, AF Chaudhary, JS Patel, TL Collier, C Ran, KS Muehlfenzl, A Haider, CS Elmore, M Schou, SH Liang | 08/14/2025 |
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18F-Flurpiridaz PET for imaging of myocardial ischemia. Trends in pharmacological sciences |
T Zhao, A Haider, SH Liang | 08/13/2025 |
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ACS pharmacology & translational science |
Y Li, K Dahl, CS Elmore, J Sandell, A Takano, C Halldin, L Farde, C Ahlgren, A Cochrane, J Rong, J Chen, C Zhao, X Zhou, JS Patel, Z Song, A Chaudhary, Y Gao, Z Sun, Z Zhang, S Feng, A Haider, SH Liang, M Schou | 07/11/2025 |
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Novel (1H‑Pyrazol-4-ylamino)pyrimidine Derivatives as Wee1 Inhibitors for Treatment of Cancer. ACS medicinal chemistry letters |
SH Liang | 07/10/2025 |
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ACS medicinal chemistry letters |
SH Liang | 07/10/2025 |
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ACS medicinal chemistry letters |
Y Li, SH Liang | 07/10/2025 |
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ACS medicinal chemistry letters |
Y Li, SH Liang | 07/10/2025 |
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ACS medicinal chemistry letters |
X Zhou, SH Liang | 07/10/2025 |
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ACS medicinal chemistry letters |
X Zhou, SH Liang | 07/10/2025 |
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Journal of medicinal chemistry |
W Ran, K Hu, W Ye, L Zhang, J Chen, B Ji, W Mori, Z Wang, H Lu, A Haider, T Yamasaki, H Huang, L Xie, Q Yang, S Yuan, X Wang, J Gong, H Wang, SH Liang, J Wang, R Wang, MR Zhang, L Wang | 06/26/2025 |
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Advances in the Structural Basis of GluN2A-Selective Negative Allosteric Modulators. ACS medicinal chemistry letters |
Y Li, H Yuan, SH Liang | 06/12/2025 |
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Deuterated 1,3 Dihydro‑2H‑indole-2-one Derivatives for Treatment of Depression or Anxiety. ACS medicinal chemistry letters |
QL Hu, SH Liang | 06/12/2025 |
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Novel 2,6,9-Trisubstituted Purines as CDK2 Inhibitors for Treating Cancers. ACS medicinal chemistry letters |
J Rong, SH Liang | 06/12/2025 |
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ACS medicinal chemistry letters |
Z Song, SH Liang | 06/12/2025 |
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Synthesis and Application of Novel Arginine Vasopressin Receptor 1A (AVPR1A) Antagonists. ACS medicinal chemistry letters |
X Zhou, SH Liang | 06/12/2025 |
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EBioMedicine |
T Shao, Z Gu, Y Liu, X Wang, C Tang, N Chen, M Wang, X Liu, H Song, S Chen, W Li, H Hui, X Jia, H Mao, RT Chung, S Liang, S Xiong, J Tian | 06/01/2025 |
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ACS medicinal chemistry letters |
Y Li, SH Liang | 05/08/2025 |
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ACS medicinal chemistry letters |
Z Song, SH Liang | 05/08/2025 |
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Novel Heterocyclic Pyrimidine Derivatives as GSK3α Inhibitors. ACS medicinal chemistry letters |
Y Li, SH Liang | 05/08/2025 |
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Novel Nonpeptide as Oxytocin Receptor Agonist. ACS medicinal chemistry letters |
Y Li, SH Liang | 05/08/2025 |
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Novel Sulfonamide Derivatives as Nav1.5 Sodium Channel Blockers for Treating Atrial Fibrillation. ACS medicinal chemistry letters |
S Feng, SH Liang | 05/08/2025 |
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ACS medicinal chemistry letters |
Z Song, SH Liang | 05/08/2025 |
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Novel Tricyclic Compounds as GSK3 Inhibitors. ACS medicinal chemistry letters |
Y Li, SH Liang | 05/08/2025 |
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ACS medicinal chemistry letters |
T Zhao, SH Liang | 05/08/2025 |
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6-Aryl Isoindolin-1-ones: Novel mGluR2 Negative Allosteric Modulators. ACS medicinal chemistry letters |
Y Li, SH Liang | 04/10/2025 |
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Enhancing the Stability of 211At Radiopharmaceuticals: Insights from Ortho-Substituent Strategies. ACS medicinal chemistry letters |
T Zhao, SH Liang | 04/10/2025 |
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ACS medicinal chemistry letters |
Y Li, SH Liang | 04/10/2025 |
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Novel Cyclic Peptides as Interleukin-23 Inhibitor for Treating Inflammatory Disorders. ACS medicinal chemistry letters |
QL Hu, SH Liang | 04/10/2025 |
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Novel Pyrazolo[1,5-a]pyrimidine-3,5-diamines as nSMase2 Inhibitors. ACS medicinal chemistry letters |
J Rong, SH Liang | 04/10/2025 |
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Novel Triazole-Substituted Imidazo[1,2-a]Pyrimidine Compounds as cGAS inhibitors. ACS medicinal chemistry letters |
T Zhao, SH Liang | 04/10/2025 |
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Preparation of Substituted Heterocycles and Their Use as DNA Polymerase Theta (POLQ) Inhibitors. ACS medicinal chemistry letters |
X Zhou, SH Liang | 04/10/2025 |
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Journal of medicinal chemistry |
C Bi, JS Patel, SH Liang | 04/10/2025 |
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ACS pharmacology & translational science |
J Rong, C Zhao, AF Chaudhary, J Chen, X Zhou, K Zhang, Z Song, Z Sun, Y Gao, Z Zhang, S Feng, TL Collier, H Yuan, JS Patel, A Haider, Y Li, SH Liang | 03/14/2025 |
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Hydroquinazoline Derivatives as Novel Natriuretic Peptide Receptor 1 (NPR1) Activators. ACS medicinal chemistry letters |
X Zhou, SH Liang | 03/13/2025 |
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ACS medicinal chemistry letters |
S Feng, SH Liang | 03/13/2025 |
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ACS medicinal chemistry letters |
Z Song, SH Liang | 03/13/2025 |
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Novel 5,6-Fused and 6,6-Fused Bicyclic Compounds as 15-Prostaglandin Dehydrogenase Modulators. ACS medicinal chemistry letters |
J Rong, SH Liang | 03/13/2025 |
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Novel Cyclic Peptides Inhibiting Tumor Necrosis Factor Receptor 1 Activity. ACS medicinal chemistry letters |
QL Hu, SH Liang | 03/13/2025 |
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ACS medicinal chemistry letters |
Y Li, SH Liang | 03/13/2025 |
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Novel Pyrimidinyl Sulfonamide Derivatives as GPR17 Modulators. ACS medicinal chemistry letters |
T Zhao, SH Liang | 03/13/2025 |
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Radiosynthesis and evaluation of novel 18F labeled PET ligands for imaging monoacylglycerol lipase. European journal of medicinal chemistry |
Y Li, W Mori, A Chaudhary, C Zhao, T Yamasaki, Z Zhang, S Feng, T Ware, J Rong, M Fujinaga, J Chen, K Kumata, Y Zhang, K Hu, L Xie, X Zhou, Z Song, Y Gao, Z Sun, JS Patel, C Zhai, KY Yuan, TL Collier, C Ran, L Collin, A Haider, U Grether, MB Wittwer, BF Cravatt, MR Zhang, SH Liang | 03/05/2025 |
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Molecular pharmaceutics |
J Rong, C Zhao, AF Chaudhary, E Jones, R Van, Z Song, Y Li, J Chen, X Zhou, JS Patel, Y Gao, Z Sun, S Feng, Z Zhang, TL Collier, C Ran, A Haider, Y Shao, H Yuan, SH Liang | 03/03/2025 |
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Cyclic Peptides Targeting Granzyme B: Potential Applications as PET Imaging Agents. ACS medicinal chemistry letters |
QL Hu, SH Liang | 02/13/2025 |
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ACS medicinal chemistry letters |
Z Song, SH Liang | 02/13/2025 |
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ACS medicinal chemistry letters |
Y Li, SH Liang | 02/13/2025 |
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Novel Tricyclic KRAS Inhibitors for the Treatment of Cancer. ACS medicinal chemistry letters |
T Zhao, SH Liang | 02/13/2025 |
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Chembiochem : a European journal of chemical biology |
Z Song, Y Li, K Dahl, A Chaudhary, Z Sun, X Zhou, J Chen, Y Gao, J Rong, C Zhao, JS Patel, L Collier, C Ran, C Zhai, L Zhang, A Haider, KS Mühlfenzl, H Yuan, CS Elmore, M Schou, SH Liang | 02/03/2025 |
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Acta pharmacologica Sinica |
K Liao, JH Chen, J Ma, CC Dong, CY Bi, YB Gao, YF Jiang, T Wang, HY Wei, L Hou, JQ Hu, JJ Wei, CY Zeng, YL Li, S Yan, H Xu, SH Liang, L Wang | 02/01/2025 |
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Synthesis, preclinical assessment, and first-in-human study of [18F]d4-FET for brain tumor imaging. European journal of nuclear medicine and molecular imaging |
L Hou, Z Chen, F Chen, L Sheng, W Ye, Y Dai, X Guo, C Dong, G Li, K Liao, Y Li, J Ma, H Wei, W Ran, J Shang, X Ling, JS Patel, SH Liang, H Xu, L Wang | 02/01/2025 |
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American journal of nuclear medicine and molecular imaging |
C Dong, W Ye, Y Xu, J Chen, K Liao, H Wei, Y Jiang, L Hou, J Wei, Z Tan, Z Song, Y Li, A Haider, H Yuan, SH Liang, L Wang | 01/01/2025 |
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American journal of nuclear medicine and molecular imaging |
C Li, Q Hu, SH Liang | 01/01/2025 |
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Multivalent FAPI-based radiopharmaceuticals in PET/CT: from cancer diagnostics to theranostics. American journal of nuclear medicine and molecular imaging |
T Zhao, SH Liang | 01/01/2025 |
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Trop2-targeted immunoPET ligands. American journal of nuclear medicine and molecular imaging |
SH Liang | 01/01/2025 |
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European journal of nuclear medicine and molecular imaging |
J Ma, S Zhang, N Yang, J Shang, X Gao, J Chen, H Wei, Y Li, H Zeng, H Xu, J Wang, SH Liang, R Wang, K Hu, L Wang | 01/01/2025 |
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Brain development during the lifespan of cynomolgus monkeys. NeuroImage |
Z Tan, B Nie, H Wu, B Li, J Shang, T Zhang, Z Xiao, C Dong, C Zeng, B Wu, L Hou, B Guo, Y Cheng, J Gong, W Ye, L Xu, Y Li, X Li, SH Liang, B Shan, H Xu, L Wang | 01/01/2025 |
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Theranostics |
A Pees, CD Morrone, J Tong, J Rong, T Shao, D Wear, SH Liang, WH Yu, N Vasdev | 01/01/2025 |
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Journal of neurochemistry |
R Song, J Zhang, RE Perszyk, CR Camp, W Tang, V Kannan, J Li, Y Xu, J Chen, Y Li, SH Liang, SF Traynelis, H Yuan | 12/01/2024 |
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Acta pharmaceutica Sinica. B |
J Hu, Y Li, C Dong, H Wei, K Liao, J Wei, C Zhao, A Chaudhary, J Chen, H Xu, K Zhong, SH Liang, L Wang, W Ye | 09/01/2024 |
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ACS pharmacology & translational science |
Y Li, K Dahl, P Johnström, K Varnäs, L Farde, C Halldin, A Medd, D Maier, ME Powell, J Chen, R Van, J Patel, A Chaudhary, Y Gao, Z Song, A Haider, Y Shao, CS Elmore, S Liang, M Schou | 08/09/2024 |
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Brain : a journal of neurology |
H Ahmed, Y Wang, WJ Griffiths, AI Levey, I Pikuleva, SH Liang, A Haider | 05/03/2024 |
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Development of Pyridothiophene Compounds for PET Imaging of α-Synuclein. Chemistry (Weinheim an der Bergstrasse, Germany) |
A Pees, J Tong, S Birudaraju, YS Munot, SH Liang, D Saturnino Guarino, RH Mach, CA Mathis, N Vasdev | 04/22/2024 |
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Journal of the American Chemical Society |
J Liu, J Rong, DP Wood, Y Wang, SH Liang, S Lin | 02/21/2024 |
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American journal of nuclear medicine and molecular imaging |
TE Jeppesen, T Shao, J Chen, JS Patel, X Zhou, A Kjaer, SH Liang | 01/01/2024 |
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Radiodifluoromethylation of well-functionalized molecules. American journal of nuclear medicine and molecular imaging |
W Zhang, Y Li, SH Liang | 01/01/2024 |
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Evaluation of [18F]RoSMA-18-d6 as a CB2 PET Radioligand in Nonhuman Primates. ACS chemical neuroscience |
A Haider, L Wang, L Gobbi, Y Li, A Chaudhary, X Zhou, J Chen, C Zhao, J Rong, Z Xiao, L Hou, NH Elghazawy, W Sippl, AT Davenport, JB Daunais, H Ahmed, R Crowe, M Honer, A Rominger, U Grether, SH Liang, SM Ametamey | 10/18/2023 |
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Translational molecular imaging and drug development in Parkinson's disease. Molecular neurodegeneration |
A Haider, NH Elghazawy, A Dawoud, C Gebhard, T Wichmann, W Sippl, M Hoener, E Arenas, SH Liang | 02/10/2023 |
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Assessment of cholesterol homeostasis in the living human brain. Science translational medicine |
A Haider, C Zhao, L Wang, Z Xiao, J Rong, X Xia, Z Chen, SK Pfister, N Mast, E Yutuc, J Chen, Y Li, T Shao, GI Warnock, A Dawoud, TR Connors, DH Oakley, H Wei, J Wang, Z Zheng, H Xu, AT Davenport, JB Daunais, RS Van, Y Shao, Y Wang, MR Zhang, C Gebhard, I Pikuleva, AI Levey, WJ Griffiths, SH Liang | 10/05/2022 |