Claire M. Mazewski, MD

Research Program

Discovery and Developmental Therapeutics
Phone Number

404-785-1112
Email Address

cmazews@emory.edu

Biography

Claire M. Mazewski, MD, is a professor in the Department of Pediatrics at Emory University School of Medicine. As a pediatric neuro-oncologist, Dr. Mazewski cares for patients at the Aflac Cancer and Blood Disorders Center of Children’s Healthcare of Atlanta. She is a member of the Discovery and Developmental Therapeutics Research Program at Winship Cancer Institute of Emory University.

Education

Dr. Mazewski earned her medical degree from the Indiana University School of Medicine. She then went on to complete her residency at Indiana University as well. She conducted her fellowship at the Cincinnati Hospital Medical Center and did her neuro-oncology training at Children’s National Medical Center in Washington, DC.

Titles & Roles

Professor, Department of Pediatrics

Emory University School of Medicine

Research

Dr. Mazewski's main areas of interest and research include treatment of childhood brain and spinal cord tumors, treatment of infants with brain tumors, late effects, new agents/clinical drug development, complementary/alternative medicine, and patient, parent and community education regarding these tumors, treatments and late effects.

View Current Clinical Trials


HeadStart4: Newly Diagnosed Children (<10 y/o) With Medulloblastoma and Other CNS Embryonal Tumors Phase IV Conditions Medulloblastoma, Central Nervous System Embryonal Tumors Location Winship Cancer Institute

Publications

Title/Journal	Authors	Publication Date
Salvage therapies for first relapse of SHH medulloblastoma in early childhood. Neuro-oncology	C Erker, M Mynarek, M Simbozel, BT Craig, VL Harrod, AM Cappellano, KJ Cohen, VS Lopez, A Morales-La Madrid, C Cacciotti, L Baroni, R Salloum, AS Margol, G Michaiel, D Aguilera, CM Mazewski, CN Kline, JL Finlay, MS Abdelbaki, JC Murray, K Dorris, B Crooks, KF Ginn, N Amayiri, S Tippelt, G Fleischhack, S Tonn, NU Gerber, A Lassaletta, JR Hansford, S Khan, SW Gilheeney, LM Hoffman, M Zapotocky, V Larouche, S Shah, V Ramaswamy, A Gajjar, S Perreault, S Mueller, J Hukin, S Cheng, ZJ Wang, K Matheson, S Bailey, E Bouffet, SC Clifford, G Robinson, C Dufour, S Rutkowski, L Lafay-Cousin	04/04/2025
Clinical Characteristics and Outcomes of Central Nervous System Tumors Harboring NTRK Gene Fusions. Clinical cancer research : an official journal of the American Association for Cancer Research	AA Lamoureux, MJ Fisher, L Lemelle, E Pfaff, P Amir-Yazdani, C Kramm, B De Wilde, B Kazanowska, C Hutter, SM Pfister, D Sturm, DTW Jones, D Orbach, G Pierron, S Raskin, A Drilon, EL Diamond, G Harada, M Zapotocky, J Zamecnik, L Krskova, B Ellezam, AG Weil, D Venne, M Barritault, P Leblond, H Coltin, R Hammad, U Tabori, C Hawkins, JR Hansford, D Meyran, C Erker, K McFadden, M Sato, NG Gottardo, H Dholaria, DS Nørøxe, H Goto, DS Ziegler, FY Lin, DW Parsons, H Lindsay, TT Wong, YL Liu, KS Wu, AT Franson, E Hwang, A Aguilar-Bonilla, S Cheng, C Cacciotti, M Massimino, E Schiavello, P Wood, LM Hoffman, A Cappellano, A Lassaletta, A Van Damme, A Llort, NU Gerber, M Spalato Ceruso, AE Bendel, M Skrypek, D Hamideh, N Mushtaq, A Walter, N Jabado, A Alsahlawi, JP Farmer, C Coleman, S Mueller, C Mazewski, D Aguilera, NJ Robison, K O'Halloran, S Abbou, P Berlanga, B Geoerger, I Øra, CL Moertel, ED Razis, A Vernadou, F Ducray, C Bronnimann, R Seizeur, M Clarke, AC Resnick, M Alves, C Jones, F Doz, TW Laetsch, S Perreault	02/03/2025
Outcomes of Infants and Young Children With Relapsed Medulloblastoma After Initial Craniospinal Irradiation-Sparing Approaches: An International Cohort Study. Journal of clinical oncology : official journal of the American Society of Clinical Oncology	C Erker, M Mynarek, S Bailey, CM Mazewski, L Baroni, M Massimino, J Hukin, D Aguilera, AM Cappellano, V Ramaswamy, A Lassaletta, S Perreault, CN Kline, R Rajagopal, G Michaiel, M Zapotocky, V Santa-Maria Lopez, AM La Madrid, C Cacciotti, ES Sandler, LM Hoffman, D Klawinski, S Khan, R Salloum, AL Hoppmann, V Larouche, K Dorris, H Toledano, SW Gilheeney, MS Abdelbaki, B Wilson, DS Tsang, J Knipstein, MY Oren, S Shah, JC Murray, KF Ginn, ZJ Wang, G Fleischhack, D Obrecht, S Tonn, VL Harrod, K Matheson, B Crooks, DR Strother, KJ Cohen, JR Hansford, S Mueller, A Margol, A Gajjar, G Dhall, JL Finlay, PA Northcott, S Rutkowski, SC Clifford, G Robinson, E Bouffet, L Lafay-Cousin	04/01/2023
Features Associated With Weight Loss and Growth Stunting for Young Children During Cancer Therapy. Journal of pediatric hematology/oncology	DV Runco, K Wasilewski-Masker, CM Mazewski, BC Patterson, AC Mertens	11/01/2021
Impact of executive functioning on health-related quality of life of pediatric brain tumor survivors. Pediatric blood & cancer	C Murphy, NC Upshaw, AS Thomas, G Fong, A Janss, C Mazewski, LM Ingerski	08/01/2021
Reply to S.A. Upadhyaya. Journal of clinical oncology : official journal of the American Society of Clinical Oncology	AT Reddy, MD Krailo, AB Buxton, DR Strother, A Huang, T Zhou, AR Judkins, PC Burger, IF Pollack, C Williams-Hughes, M Fouladi, B Ho, CM Mazewski, VA Lewis, LG Vezina, TN Booth, A Mahajan	10/01/2020
Normalized measures and patient characteristics to identify undernutrition in infants and young children treated for cancer. Clinical nutrition ESPEN	DV Runco, K Wasilewski-Masker, CE McCracken, M Wetzel, CM Mazewski, BC Patterson, AC Mertens	08/01/2020
Efficacy of High-Dose Chemotherapy and Three-Dimensional Conformal Radiation for Atypical Teratoid/Rhabdoid Tumor: A Report From the Children's Oncology Group Trial ACNS0333. Journal of clinical oncology : official journal of the American Society of Clinical Oncology	AT Reddy, DR Strother, AR Judkins, PC Burger, IF Pollack, MD Krailo, AB Buxton, C Williams-Hughes, M Fouladi, A Mahajan, TE Merchant, B Ho, CM Mazewski, VA Lewis, A Gajjar, LG Vezina, TN Booth, KW Parsons, VL Poss, T Zhou, JA Biegel, A Huang	04/10/2020
A Review of Chronic Leukoencephalopathy among Survivors of Childhood Cancer. Pediatric neurology	S Partap, S Russo, B Esfahani, K Yeom, C Mazewski, L Embry, G Wheeler, NJ Ullrich, DC Bowers	12/01/2019
Guidelines for Treatment and Monitoring of Adult Survivors of Pediatric Brain Tumors. Current treatment options in oncology	AJ Janss, C Mazewski, B Patterson	02/09/2019
Clinical responses of patients with diffuse leptomeningeal glioneuronal tumors to chemotherapy. Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery	D Aguilera, RC Castellino, A Janss, M Schniederjan, R McNall, T MacDonald, C Mazewski	02/01/2018
Morbidity and Mortality Associated With Meningioma After Cranial Radiotherapy: A Report From the Childhood Cancer Survivor Study. Journal of clinical oncology : official journal of the American Society of Clinical Oncology	DC Bowers, CS Moskowitz, JF Chou, CM Mazewski, JP Neglia, GT Armstrong, WM Leisenring, LL Robison, KC Oeffinger	05/10/2017
Nonrandomized comparison of neurofibromatosis type 1 and non-neurofibromatosis type 1 children who received carboplatin and vincristine for progressive low-grade glioma: A report from the Children's Oncology Group. Cancer	JL Ater, C Xia, CM Mazewski, TN Booth, DR Freyer, RJ Packer, R Sposto, G Vezina, IF Pollack	06/15/2016
Endocrine outcomes with proton and photon radiotherapy for standard risk medulloblastoma. Neuro-oncology	BR Eaton, N Esiashvili, S Kim, B Patterson, EA Weyman, LT Thornton, C Mazewski, TJ MacDonald, D Ebb, SM MacDonald, NJ Tarbell, TI Yock	06/01/2016
Successful Retreatment of a Child with a Refractory Brainstem Ganglioglioma with Vemurafenib. Pediatric blood & cancer	D Aguilera, A Janss, C Mazewski, RC Castellino, M Schniederjan, L Hayes, B Brahma, L Fogelgren, TJ MacDonald	03/01/2016
Clinical Outcomes Among Children With Standard-Risk Medulloblastoma Treated With Proton and Photon Radiation Therapy: A Comparison of Disease Control and Overall Survival. International journal of radiation oncology, biology, physics	BR Eaton, N Esiashvili, S Kim, EA Weyman, LT Thornton, C Mazewski, T MacDonald, D Ebb, SM MacDonald, NJ Tarbell, TI Yock	01/01/2016
Response of subependymal giant cell astrocytoma with spinal cord metastasis to everolimus. Journal of pediatric hematology/oncology	D Aguilera, R Flamini, C Mazewski, M Schniederjan, L Hayes, W Boydston, RC Castellino, TJ MacDonald	10/01/2014
Mandibular condyle erosion and sclerosis in pediatric patients treated with radiotherapy to the head and neck region. Pediatric blood & cancer	CE Mercado, SB Little, C Mazewski, FP Schwaibold, N Esiashvili	08/01/2014
Diffuse leptomeningeal neuroepithelial tumor: 9 pediatric cases with chromosome 1p/19q deletion status and IDH1 (R132H) immunohistochemistry. The American journal of surgical pathology	MJ Schniederjan, S Alghamdi, A Castellano-Sanchez, C Mazewski, B Brahma, DJ Brat, CD Brathwaite, AJ Janss	05/01/2013
Response to bevacizumab, irinotecan, and temozolomide in children with relapsed medulloblastoma: a multi-institutional experience. Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery	D Aguilera, C Mazewski, J Fangusaro, TJ MacDonald, RY McNall-Knapp, LL Hayes, S Kim, RC Castellino	04/01/2013
Prolonged survival after treatment of diffuse intrinsic pontine glioma with radiation, temozolamide, and bevacizumab: report of 2 cases. Journal of pediatric hematology/oncology	DG Aguilera, C Mazewski, L Hayes, C Jordan, N Esiashivilli, A Janns, TJ Macdonald	01/01/2013
Transient enlargement of craniopharyngioma after radiation therapy: pattern of magnetic resonance imaging response following radiation. Journal of neuro-oncology	Z Shi, N Esiashvili, AJ Janss, CM Mazewski, TJ MacDonald, DM Wrubel, B Brahma, FP Schwaibold, RB Marcus, IR Crocker, HK Shu	09/01/2012
Randomized study of two chemotherapy regimens for treatment of low-grade glioma in young children: a report from the Children's Oncology Group. Journal of clinical oncology : official journal of the American Society of Clinical Oncology	JL Ater, T Zhou, E Holmes, CM Mazewski, TN Booth, DR Freyer, KH Lazarus, RJ Packer, M Prados, R Sposto, G Vezina, JH Wisoff, IF Pollack	07/20/2012
Intracranial metastatic neuroblastoma treated with gamma knife stereotactic radiosurgery: report of two novel cases. Case reports in neurological medicine	NC Rowland, J Andrews, D Patel, DV Laborde, A Nowlan, B George, C Mazewski, A Reisner, HM Katzenstein	01/01/2012
Neurofibromatosis-2 and spinal cord ependymomas: Report of two cases and review of the literature. Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery	DG Aguilera, C Mazewski, MJ Schniederjan, T Leong, W Boydston, TJ Macdonald	05/01/2011
Incidence, risks, and sequelae of posterior fossa syndrome in pediatric medulloblastoma. International journal of radiation oncology, biology, physics	MP Korah, N Esiashvili, CM Mazewski, RJ Hudgins, M Tighiouart, AJ Janss, FP Schwaibold, IR Crocker, WJ Curran, RB Marcus	05/01/2010
Intensive multimodality treatment for children with newly diagnosed CNS atypical teratoid rhabdoid tumor. Journal of clinical oncology : official journal of the American Society of Clinical Oncology	SN Chi, MA Zimmerman, X Yao, KJ Cohen, P Burger, JA Biegel, LB Rorke-Adams, MJ Fisher, A Janss, C Mazewski, S Goldman, PE Manley, DC Bowers, A Bendel, J Rubin, CD Turner, KJ Marcus, L Goumnerova, NJ Ullrich, MW Kieran	01/20/2009
Off-therapy headaches in pediatric brain tumor patients: a retrospective review. Journal of pediatric oncology nursing : official journal of the Association of Pediatric Oncology Nurses	AH Johnson, C Jordan, CM Mazewski	01/01/2009