Gabriela Oprea-Ilies, MD

Specialty

Breast Cancer
Research Program

Discovery and Developmental Therapeutics
Phone Number

404-616-7449
Email Address

goprea@emory.edu

Biography

Gabriela Oprea-Ilies, MD, is an associate professor in the Department of Pathology and Laboratory Medicine at Emory University School of Medicine. Dr. Oprea-Ilies provides pathology and cytology services at Grady Memorial Hospital.

Education

Dr. Oprea-Ilieas earned her MD from the Institute of Medicine and Pharmacology in Romania. After obtaining her PhD, Dr. Oprea-Ilieas completed residency programs at Emergency Hospital in Romania, Regions Medical Center in Minnesota, and the University of Minnesota. She also completed fellowships at the University of Minnesota and Emory University School of Medicine.

Titles & Roles

Associate Professor, Department of Pathology and Laboratory Medicine

Emory University School of Medicine

Research

Dr. Oprea-Ilies studies the in-homogenous nature of breast cancer, and as the principal investigator of the breast tissue bank, she is interested in questioning the molecular events of breast carcinogenesis in the context of its in-homogeneity as applied to a racially diverse, economically challenged population. She is also interested in HIV infection in women, and she studies the effect of the HIV infection, from reactive to neoplastic, on different organs and systems, with emphasis on women's health issues.

Publications

Title/Journal	Authors	Publication Date
A pilot study of the immune microenvironment of GI neuroendocrine carcinoma. Endocrine-related cancer	A McDonald, V Avadhani, G Oprea-Ilies, K Zakka, GB Lesinski, OB Gbolahan, O Alese	10/01/2024
Social and Biological Determinants in Lung Cancer Disparity. Cancers	BA Brock, H Mir, EL Flenaugh, G Oprea-Ilies, R Singh, S Singh	01/31/2024
Targeted Therapy and Mechanisms of Drug Resistance in Breast Cancer. Cancers	B Kinnel, SK Singh, G Oprea-Ilies, R Singh	02/19/2023
The EMory BrEast imaging Dataset (EMBED): A Racially Diverse, Granular Dataset of 3.4 Million Screening and Diagnostic Mammographic Images. Radiology. Artificial intelligence	JJ Jeong, BL Vey, A Bhimireddy, T Kim, T Santos, R Correa, R Dutt, M Mosunjac, G Oprea-Ilies, G Smith, M Woo, CR McAdams, MS Newell, I Banerjee, J Gichoya, H Trivedi	01/01/2023
Extranodal extension, an international survey on its evaluation and reporting in breast cancer patients. Pathology, research and practice	P Tang, M Moravek, G Oprea-Ilies, KS Mon, SE Pambuccian	09/01/2022
Potential Refinement of Recurrence Score by pSTAT3 Status. Genes	A Grinshpun, Y Cohen, A Zick, L Kadouri, T Hamburger, B Nisman, TM Allweis, G Oprea, T Peretz, B Uziely, A Sonnenblick	02/27/2022
The interplay of pineal hormones and socioeconomic status leading to colorectal cancer disparity. Translational oncology	T Haynes, G Oprea-Ilies, U Manne, R Singh, S Singh, H Mir	02/01/2022
Nano-Based Drug Delivery and Targeting to Overcome Drug Resistance of Ovarian Cancers. Cancers	M McFadden, SK Singh, G Oprea-Ilies, R Singh	10/31/2021
CXCR6-CXCL16 Axis Promotes Breast Cancer by Inducing Oncogenic Signaling. Cancers	H Mir, N Kapur, DN Gales, PK Sharma, G Oprea-Ilies, AT Johnson, R Singh, S Singh	07/16/2021
Clot composition in retrieved thrombi after mechanical thrombectomy in strokes due to carotid web. Journal of neurointerventional surgery	S Koneru, RG Nogueira, E Osehobo, G Oprea-Ilies, AR Al-Bayati, W Brinjikji, D Dai, DC Haussen	06/01/2021
Assessment and Efficacy of Low-Dose CT Screening and Primary Care Providers Perspective on Lung Cancer Screening: An Institutional Review. Cureus	M Shah, PK Surapaneni, K Sandhu, S Shafi, T Abe, S Jain, G Oprea, J Volcy	03/09/2021
Invasive Pulmonary Aspergillosis with Hydropneumothorax in a Patient Taking High-Dose Glucocorticoids. The American journal of case reports	D Dixit, NT Kuete, P Bene, I Khan, G Oprea-Ilies, E Flenaugh	12/28/2020
Novel role for the Golgi membrane protein TMEM165 in control of migration and invasion for breast carcinoma. Oncotarget	P Murali, BP Johnson, Z Lu, L Climer, DA Scott, F Foulquier, G Oprea-Ilies, V Lupashin, RR Drake, KL Abbott	07/14/2020
Diagnosing Anal Squamous Intraepithelial Lesions With and Without p16: An Interobserver Variability Study. Journal of lower genital tract disease	U Krishnamurti, M Mohammad, A Monsrud, M Mosunjac, G Oprea, K Hanley, T Tadros, L Flowers, M Mosunjac	01/01/2020
Prognostic Role of Androgen Receptor in Triple Negative Breast Cancer: A Multi-Institutional Study. Cancers	S Bhattarai, S Klimov, K Mittal, U Krishnamurti, XB Li, G Oprea-Ilies, CS Wetherilt, A Riaz, MA Aleskandarany, AR Green, IO Ellis, G Cantuaria, M Gupta, U Manne, J Agboola, B Baskovich, EAM Janssen, G Callagy, EM Walsh, A Mehta, A Dogra, T Shet, P Gajaria, T Traina, HA Nggada, A Omonisi, SA Ahmed, EA Rakha, P Rida, R Aneja	07/17/2019
Leptin-induced Notch and IL-1 signaling crosstalk in endometrial adenocarcinoma is associated with invasiveness and chemoresistance. World journal of clinical oncology	D Daley-Brown, A Harbuzariu, AA Kurian, G Oprea-Ilies, RR Gonzalez-Perez	06/24/2019
Ectopic ACTH Syndrome With Association of Multiple Pulmonary Sclerosing Pneumocytomas and Multiple Carcinoid Tumorlets. Journal of the Endocrine Society	E Benito-Martínez, F Galeano-Valle, A González, MA Edgar, G Oprea-Ilies, AG Ioachimescu, FJ Pasquel	05/01/2019
An atypical presentation of diabetic myonecrosis. AACE clinical case reports	F Galeano-Valle, E Benito-Martinez, L Álvarez-Sala-Walther, G Oprea-Ilies, GE Umpierrez, FJ Pasquel	01/01/2019
The Role of Notch Signaling and Leptin-Notch Crosstalk in Pancreatic Cancer. Medicines (Basel, Switzerland)	A Harbuzariu, GM Oprea-Ilies, RR Gonzalez-Perez	07/02/2018
What Should a Gynecologist Know about Li-Fraumeni Syndrome? Lessons from a Patient Undergoing Hysterectomy for Benign Indications. Gynecologic and obstetric investigation	P Advolodkina, MP Lachiewicz, G Oprea-Ilies, B Majmudar, AN Gordon	01/01/2018
New Developments in Breast Cancer and Their Impact on Daily Practice in Pathology. Archives of pathology & laboratory medicine	X Li, GM Oprea-Ilies, U Krishnamurti	04/01/2017
Multi-institutional study of nuclear KIFC1 as a biomarker of poor prognosis in African American women with triple-negative breast cancer. Scientific reports	A Ogden, C Garlapati, XB Li, RC Turaga, G Oprea-Ilies, N Wright, S Bhattarai, K Mittal, CS Wetherilt, U Krishnamurti, MD Reid, M Jones, M Gupta, R Osan, S Pattni, A Riaz, S Klimov, A Rao, G Cantuaria, PC Rida, R Aneja	02/20/2017
Leptin-Notch signaling axis is involved in pancreatic cancer progression. Oncotarget	A Harbuzariu, A Rampoldi, DS Daley-Brown, P Candelaria, TL Harmon, CC Lipsey, DJ Beech, A Quarshie, GO Ilies, RR Gonzalez-Perez	01/31/2017
Spontaneous Pneumothoraces due to Metastatic Endometrial Stromal Sarcoma in a Woman Infected with HIV. American journal of respiratory and critical care medicine	DJ Shah, VK Phadke, G Oprea-Ilies, EA Berkowitz, ML Nguyen, AN Sheth	01/01/2016
Chemotherapy Used to Halt Lower GI Bleeding in a Rare Case of Metastatic Choriocarcinoma to the GI Tract. Case reports in oncological medicine	R Kamel, T Seoud, T Oluwadamilola, M Karass, E Grossniklaus, G Oprea-Ilies, DA Goldstein, S Jain	01/01/2016
GATA-3 and FOXA1 expression is useful to differentiate breast carcinoma from other carcinomas. Human pathology	DG Davis, MT Siddiqui, G Oprea-Ilies, K Stevens, AO Osunkoya, C Cohen, XB Li	01/01/2016
Silencing of E2F3 suppresses tumor growth of Her2+ breast cancer cells by restricting mitosis. Oncotarget	M Lee, G Oprea-Ilies, HI Saavedra	11/10/2015
Metastatic colorectal cancer in a cirrhotic liver with synchronous hepatocellular carcinoma. Annals of translational medicine	M Karass, E Grossniklaus, T Seoud, R Kamel, O Teniola, G Oprea, DA Goldstein, S Jain	11/01/2015
The 21-gene recurrence score and locoregional recurrence in breast cancer patients. Annals of surgical oncology	NK Jegadeesh, S Kim, RS Prabhu, GM Oprea, DS Yu, KG Godette, AB Zelnak, D Mister, JM Switchenko, MA Torres	04/01/2015
Endometrial carcinoma with ectopic human chorionic gonadotropin expression. Gynecologic oncology reports	R Lee, R Pattillo, M Bouzyk, G Oprea-Ilies, R Matthews	04/01/2015
Atypical Findings on Cervicovaginal Smears Correlate with Cervical Involvement by Malignant Mixed Müllerian Tumors of the Uterus. Acta cytologica	KZ Hanley, G Oprea-Ilies, C Ormenisan, S Seydafkan, MB Mosunjac	01/01/2015
Improved survival in p16-positive vaginal cancers across all tumor stages but no correlation with MIB-1. American journal of clinical pathology	VM Feldbaum, LC Flowers, GM Oprea-Ilies	11/01/2014
NILCO biomarkers in breast cancer from Chinese patients. BMC cancer	LS Colbert, K Wilson, S Kim, Y Liu, G Oprea-Ilies, C Gillespie, T Dickson, G Newman, RR Gonzalez-Perez	04/09/2014
Triple-negative breast carcinoma in African American and Caucasian women: clinicopathology, immunomarkers, and outcome. Applied immunohistochemistry & molecular morphology : AIMM	HC Sullivan, G Oprea-Ilies, AL Adams, AJ Page, S Kim, J Wang, C Cohen	01/01/2014
A Novel Pathway that Links Caveolin-1 Down-Regulation to BRCA1 Dysfunction in Serous Epithelial Ovarian Cancer Cells. Enliven. Challenges in cancer detection and therapy	J Xu, S Agyemang, Y Qin, K Aysola, M Giles, G Oprea, RM O'Regan, EE Partridge, S Harris-Hooker, VM Rice, ES Reddy, VN Rao	01/01/2014
Wnt signaling in triple negative breast cancer is associated with metastasis. BMC cancer	N Dey, BG Barwick, CS Moreno, M Ordanic-Kodani, Z Chen, G Oprea-Ilies, W Tang, C Catzavelos, KF Kerstann, GW Sledge, M Abramovitz, M Bouzyk, P De, BR Leyland-Jones	11/10/2013
Expression of melatonin receptors in triple negative breast cancer (TNBC) in African American and Caucasian women: relation to survival. Breast cancer research and treatment	G Oprea-Ilies, E Haus, L Sackett-Lundeen, Y Liu, L McLendon, R Busch, A Adams, C Cohen	02/01/2013
IRAK4 and TLR3 Sequence Variants may Alter Breast Cancer Risk among African-American Women. Frontiers in immunology	ST Yeyeodu, LR Kidd, GM Oprea-Ilies, BG Burns, TT Vancleave, JY Shim, KS Kimbro	01/01/2013
Proteomic identification of glycosylphosphatidylinositol anchor-dependent membrane proteins elevated in breast carcinoma. The Journal of biological chemistry	P Zhao, AV Nairn, S Hester, KW Moremen, RM O'Regan, G Oprea, L Wells, M Pierce, KL Abbott	07/20/2012
Pseudoangiomatous stromal hyperplasia (PASH) of the breast: a series of 24 patients. The breast journal	E Bowman, G Oprea, J Okoli, K Gundry, M Rizzo, S Gabram-Mendola, U Manne, G Smith, S Pambuccian, HL Bumpers	01/01/2012
Acidophilic nuclear inclusions are specific for florid ductal hyperplasia among proliferative breast lesions. Archives of pathology & laboratory medicine	S Lauer, G Oprea-Ilies, C Cohen, V Adsay, AL Adams	06/01/2011
Infectious disease immunohistochemistry in placentas from HIV-positive and HIV-negative patients. Pediatric and developmental pathology : the official journal of the Society for Pediatric Pathology and the Paediatric Pathology Society	AN Schuetz, J Guarner, MM Packard, SR Zaki, BM Shehata, G Opreas-Ilies	01/01/2011
Reed-Sternberg cells in breast FNA of a patient with left breast mass. Diagnostic cytopathology	J Park, M Rizzo, S Jackson, SR Bates, V Green, G Oprea-Ilies	09/01/2010
Age/race differences in HER2 testing and in incidence rates for breast cancer triple subtypes: a population-based study and first report. Cancer	MJ Lund, EN Butler, BY Hair, KC Ward, JH Andrews, G Oprea-Ilies, AR Bayakly, RM O'Regan, PM Vertino, JW Eley	06/01/2010
A unique benign mucinous cystadenoma of the retroperitoneum: a case report and review of the literature. Archives of gynecology and obstetrics	EB Tapper, AB Shrewsberry, G Oprea, B Majmudar	01/01/2010
Aberrant STYK1 expression in ovarian cancer tissues and cell lines. Journal of ovarian research	KA Jackson, G Oprea, J Handy, KS Kimbro	10/21/2009
High prevalence of triple-negative tumors in an urban cancer center. Cancer	MJ Lund, EN Butler, HL Bumpers, J Okoli, M Rizzo, N Hatchett, VL Green, OW Brawley, GM Oprea-Ilies, SG Gabram	08/01/2008
Surgical follow-up and clinical presentation of 142 breast papillary lesions diagnosed by ultrasound-guided core-needle biopsy. Annals of surgical oncology	M Rizzo, MJ Lund, G Oprea, M Schniederjan, WC Wood, M Mosunjac	04/01/2008