Gabriel Sica, MD, PhD

Role

Anatomic Pathology, Clinical and Laboratory Pathology
Specialty

Lung Cancer
Research Program

Discovery and Developmental Therapeutics
Practicing Since

2009

Background

Gabriel Sica, MD, PhD, is a professor in the Department of Pathology and Laboratory Medicine at Emory University School of Medicine.

A board-certified anatomic pathologist, Dr. Sica's clinical interests lie primarily in the pathology of the lungs, pleura and mediastinum. He is especially interested in the pathology of neuroendocrine tumors of the lung such as typical carcinoids, atypical carcinoid, small cell carcinoma and large cell neuroendocrine carcinoma.

Dr. Sica earned his medical degree from Mayo Medical School in Rochester, Minnesota. He completed his internship at Rhode Island Hospital in Providence, Rhode Island and his residency at New York Presbyterian Hospital in New York City, New York. He completed his fellowship training at Memorial Sloan-Kettering in New York City, New York.

Titles & Roles

Professor, Department of Pathology and Laboratory Medicine

Emory University School of Medicine

Education & Training

Education

Fellowship, Surgical Pathology, 2009
Memorial Sloan Kettering Cancer Center
Fellowship, Thoracic Pathology, 2008
Memorial Sloan-Kettering-NY
Residency, Anatomic & Clinical Pathology, 2007
New York - Presbyterian Hospital
Internship, Internal Medicine, 2004
Brown University / Rhode Island Hospital
Medical Education, MD, 2003
Mayo Clinic School of Medicine

Board Certifications

Anatomic Pathology
American Board of Pathology, 2008

Research

Dr. Sica’s research focuses primarily on the pathobiology of lung cancer and the influence of the tumor microenvironment on disease progression and treatment response. In collaboration with his colleagues, he has identified several potential biomarkers for disease management. He aims to incorporate digital pathology analysis platforms into these studies.

Current areas of investigation include:

Subtypes and genomics of small cell lung carcinoma
Morphologic features of lung cancer and its stroma, and their impact on disease biology
Grading of neuroendocrine tumors
Senescence and its role in the immune response to lung carcinoma

Grants

View Grants

Grant Number	Title
5P50CA217691-05	Core 2: Pathology Core

Publications

Title/Journal	Authors	Publication Date
Uncovering the rewired IAP-JAK regulatory axis as an immune-dependent vulnerability of LKB1-mutant lung cancer. Nature communications	C Shu, J Li, J Rui, D Fan, Q Niu, R Bai, D Cicka, S Doyle, A Wahafu, X Zheng, Y Du, AA Ivanov, DB Doxie, KM Dhodapkar, J Carlisle, T Owonikoko, G Sica, Y Liu, S Ramalingam, MV Dhodapkar, W Zhou, X Mo, H Fu	03/08/2025
Polo-like Kinase 1 Inhibitors Demonstrate In Vitro and In Vivo Efficacy in Preclinical Models of Small Cell Lung Cancer. Cancers	G Zhang, A Pannucci, AA Ivanov, J Switchenko, SY Sun, GL Sica, Z Liu, Y Huang, JC Schmitz, TK Owonikoko	01/28/2025
Characteristics and anatomic location of PD-1⁺TCF1⁺ stem-like CD8 T cells in chronic viral infection and cancer. Proceedings of the National Academy of Sciences of the United States of America	SJ Im, RC Obeng, TH Nasti, D McManus, AO Kamphorst, S Gunisetty, N Prokhnevska, JW Carlisle, K Yu, GL Sica, LE Cardozo, ANA Gonçalves, HT Kissick, HI Nakaya, SS Ramalingam, R Ahmed	10/10/2023
EGFR-phosphorylated GDH1 harmonizes with RSK2 to drive CREB activation and tumor metastasis in EGFR-activated lung cancer. Cell reports	J Kang, J Chun, JS Hwang, C Pan, J Li, AC Boese, I Young, CM Malin, Y Kang, DL Gibbons, G Sica, H Fu, SS Ramalingam, L Jin, S Kang	12/13/2022
YAP1 Expression in SCLC Defines a Distinct Subtype With T-cell-Inflamed Phenotype. Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer	TK Owonikoko, B Dwivedi, Z Chen, C Zhang, B Barwick, V Ernani, G Zhang, M Gilbert-Ross, J Carlisle, FR Khuri, WJ Curran, AA Ivanov, H Fu, S Lonial, SS Ramalingam, SY Sun, EK Waller, GL Sica	03/01/2021
Leflunomide Suppresses the Growth of LKB1-Inactivated Tumors in the Immune-Competent Host and Attenuates Distant Cancer Metastasis. Molecular cancer therapeutics	R Jin, B Liu, X Liu, Y Fan, W Peng, C Huang, A Marcus, G Sica, M Gilbert-Ross, Y Liu, W Zhou	02/01/2021
Epigenetic modulation of FBW7/Mcl-1 pathway for lung cancer therapy. Cancer biology & therapy	MJ Kim, G Chen, GL Sica, X Deng	01/02/2021
Discovery of Small Molecule Bak Activator for Lung Cancer Therapy. Theranostics	D Park, ASM Anisuzzaman, AT Magis, G Chen, M Xie, G Zhang, M Behera, GL Sica, SS Ramalingam, TK Owonikoko, X Deng	01/01/2021
Incidental Detection of Lung Adenocarcinoma Presenting as an Anterior Mediastinal Mass on 18F-Fluciclovine PET/CT in a Patient With Primary Prostate Cancer. Clinical nuclear medicine	OA Abiodun-Ojo, AA Akintayo, GL Sica, M Alemozaffar, DM Schuster	12/01/2020
Durvalumab and tremelimumab with or without stereotactic body radiation therapy in relapsed small cell lung cancer: a randomized phase II study. Journal for immunotherapy of cancer	S Pakkala, K Higgins, Z Chen, G Sica, C Steuer, C Zhang, G Zhang, S Wang, MS Hossain, B Nazha, T Beardslee, FR Khuri, W Curran, S Lonial, EK Waller, S Ramalingam, TK Owonikoko	12/01/2020
Bcl2-induced DNA replication stress promotes lung carcinogenesis in response to space radiation. Carcinogenesis	M Xie, D Park, GL Sica, X Deng	11/13/2020
Round Robin Evaluation of MET Protein Expression in Lung Adenocarcinomas Improves Interobserver Concordance. Applied immunohistochemistry & molecular morphology : AIMM	TA Boyle, FK Khalil, M Mino-Kenudson, GL Sica, AL Moreira, LM Sholl, MZ Knight, L Zhang, J Saller, M Varella-Garcia, LD Berry, H Chen, KE Ellison, CJ Rivard, K Kugler, II Wistuba, J Fujimoto, DJ Kwiatkowski, PA Bunn, MG Kris, EB Haura, FR Hirsch	10/01/2020
Granulomatous lung disease: clinical aspects. Expert review of respiratory medicine	A Chopra, V Avadhani, A Tiwari, EC Riemer, G Sica, MA Judson	10/01/2020
A Phase I Study of Safety, Pharmacokinetics, and Pharmacodynamics of Concurrent Everolimus and Buparlisib Treatment in Advanced Solid Tumors. Clinical cancer research : an official journal of the American Association for Cancer Research	TK Owonikoko, RD Harvey, B Carthon, Z Chen, C Lewis, H Collins, C Zhang, DH Lawson, OB Alese, MA Bilen, GL Sica, CE Steuer, WL Shaib, C Wu, WB Harris, M Akce, RR Kudchagkar, BF El-Rayes, S Lonial, SS Ramalingam, FR Khuri	06/01/2020
Correction to: Small Molecule KRAS Agonist for Mutant KRAS Cancer Therapy. Molecular cancer	K Xu, D Park, AT Magis, J Zhang, W Zhou, GL Sica, SS Ramalingam, WJ Curran, X Deng	05/20/2020
Mcl-1 Interacts with Akt to Promote Lung Cancer Progression. Cancer research	D Park, AT Magis, M Behera, SS Ramalingam, TK Owonikoko, GL Sica, K Ye, C Zhang, Z Chen, WJ Curran, X Deng	12/15/2019
The Biospecimen Preanalytical Variables Program: A Multiassay Comparison of Effects of Delay to Fixation and Fixation Duration on Nucleic Acid Quality. Archives of pathology & laboratory medicine	LJ Carithers, R Agarwal, P Guan, H Odeh, MC Sachs, KB Engel, SR Greytak, M Barcus, C Soria, CJ Lih, PM Williams, PA Branton, L Sobin, B Fombonne, T Bocklage, C Andry, ER Duffy, G Sica, R Dhir, S Jewell, N Roche, HM Moore	09/01/2019
Characteristics and Outcomes of Patients With Metastatic KRAS-Mutant Lung Adenocarcinomas: The Lung Cancer Mutation Consortium Experience. Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer	B El Osta, M Behera, S Kim, LD Berry, G Sica, RN Pillai, TK Owonikoko, MG Kris, BE Johnson, DJ Kwiatkowski, LM Sholl, DL Aisner, PA Bunn, FR Khuri, SS Ramalingam	05/01/2019
Small Molecule KRAS Agonist for Mutant KRAS Cancer Therapy. Molecular cancer	K Xu, D Park, AT Magis, J Zhang, W Zhou, GL Sica, SS Ramalingam, WJ Curran, X Deng	04/10/2019
A peripheral cause of asthma: Peripheral T-cell lymphoma. Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology	RP Ramonell, M Kuruvilla, G Sica, R Bag, F Eun-Hyung Lee	04/01/2019
Randomized Phase II Trial of Cisplatin and Etoposide in Combination With Veliparib or Placebo for Extensive-Stage Small-Cell Lung Cancer: ECOG-ACRIN 2511 Study. Journal of clinical oncology : official journal of the American Society of Clinical Oncology	TK Owonikoko, SE Dahlberg, GL Sica, LI Wagner, JL Wade, G Srkalovic, BW Lash, JW Leach, TB Leal, C Aggarwal, SS Ramalingam	01/20/2019
Targeted sequencing and intracranial outcomes of patients with lung adenocarcinoma brain metastases treated with radiotherapy. Cancer	RH Press, C Zhang, RJ Cassidy, MJ Ferris, J Zhong, CE Steuer, RN Pillai, TK Owonikoko, S Kahn, SS Ramalingam, PR Patel, WJ Curran, HG Shu, GL Sica, KA Higgins	09/01/2018
Orthopedia homeobox is preferentially expressed in typical carcinoids of the lung. Cancer cytopathology	KZ Hanley, ZJ Dureau, C Cohen, DM Shin, TK Owonikoko, GL Sica	04/01/2018
Vimentin Is Required for Lung Adenocarcinoma Metastasis via Heterotypic Tumor Cell-Cancer-Associated Fibroblast Interactions during Collective Invasion. Clinical cancer research : an official journal of the American Association for Cancer Research	AM Richardson, LS Havel, AE Koyen, JM Konen, J Shupe, WG Wiles, WD Martin, HE Grossniklaus, G Sica, M Gilbert-Ross, AI Marcus	01/15/2018
Targeting Mcl-1 enhances DNA replication stress sensitivity to cancer therapy. The Journal of clinical investigation	G Chen, AT Magis, K Xu, D Park, DS Yu, TK Owonikoko, GL Sica, SW Satola, SS Ramalingam, WJ Curran, PW Doetsch, X Deng	01/02/2018
Prognostic biomarkers in patients with human immunodeficiency virus-positive disease with head and neck squamous cell carcinoma. Head & neck	H Zhang, S Kim, Z Chen, S Nannapaneni, AY Chen, CE Moore, G Sica, M Mosunjac, MLT Nguyen, G D'Souza, TE Carey, LA Peterson, JB McHugh, M Graham, CM Komarck, GT Wolf, HM Walline, E Bellile, J Riddell, SI Pai, D Sidransky, WH Westra, WN William, JJ Lee, AK El-Naggar, RL Ferris, R Seethala, JR Grandis, ZG Chen, NF Saba, DM Shin	12/01/2017
Next-generation sequencing and clinical outcomes of patients with lung adenocarcinoma treated with stereotactic body radiotherapy. Cancer	RJ Cassidy, X Zhang, PR Patel, JW Shelton, CE Escott, GL Sica, MR Rossi, CE Hill, CE Steuer, RN Pillai, SS Ramalingam, TK Owonikoko, M Behera, SD Force, FG Fernandez, WJ Curran, KA Higgins	10/01/2017
Assays for PD-L1 Expression: Do All Roads Lead to Rome? JAMA oncology	GL Sica, SS Ramalingam	08/01/2017
Modulation of Bax and mTOR for Cancer Therapeutics. Cancer research	R Li, C Ding, J Zhang, M Xie, D Park, Y Ding, G Chen, G Zhang, M Gilbert-Ross, W Zhou, AI Marcus, SY Sun, ZG Chen, GL Sica, SS Ramalingam, AT Magis, H Fu, FR Khuri, WJ Curran, TK Owonikoko, DM Shin, J Zhou, X Deng	06/01/2017
Proliferation of PD-1+ CD8 T cells in peripheral blood after PD-1-targeted therapy in lung cancer patients. Proceedings of the National Academy of Sciences of the United States of America	AO Kamphorst, RN Pillai, S Yang, TH Nasti, RS Akondy, A Wieland, GL Sica, K Yu, L Koenig, NT Patel, M Behera, H Wu, M McCausland, Z Chen, C Zhang, FR Khuri, TK Owonikoko, R Ahmed, SS Ramalingam	05/09/2017
Rescue of exhausted CD8 T cells by PD-1-targeted therapies is CD28-dependent. Science (New York, N.Y.)	AO Kamphorst, A Wieland, T Nasti, S Yang, R Zhang, DL Barber, BT Konieczny, CZ Daugherty, L Koenig, K Yu, GL Sica, AH Sharpe, GJ Freeman, BR Blazar, LA Turka, TK Owonikoko, RN Pillai, SS Ramalingam, K Araki, R Ahmed	03/31/2017
Targeting adhesion signaling in KRAS, LKB1 mutant lung adenocarcinoma. JCI insight	M Gilbert-Ross, J Konen, J Koo, J Shupe, BS Robinson, WG Wiles, C Huang, WD Martin, M Behera, GH Smith, CE Hill, MR Rossi, GL Sica, M Rupji, Z Chen, J Kowalski, AL Kasinski, SS Ramalingam, H Fu, FR Khuri, W Zhou, AI Marcus	03/09/2017
Cardiac allograft rejection as a complication of PD-1 checkpoint blockade for cancer immunotherapy: a case report. Cancer immunology, immunotherapy : CII	TK Owonikoko, M Kumar, S Yang, AO Kamphorst, RN Pillai, R Akondy, V Nautiyal, MS Chatwal, WM Book, A Sahu, GL Sica, R Ahmed, SS Ramalingam	01/01/2017
Non-neutralizing antibodies induced by seasonal influenza vaccine prevent, not exacerbate A(H1N1)pdm09 disease. Scientific reports	JH Kim, AJ Reber, A Kumar, P Ramos, G Sica, N Music, Z Guo, M Mishina, J Stevens, IA York, J Jacob, S Sambhara	11/16/2016
Lung Adenocarcinoma Staging Using the 2011 IASLC/ATS/ERS Classification: A Pooled Analysis of Adenocarcinoma In Situ and Minimally Invasive Adenocarcinoma. Clinical lung cancer	M Behera, TK Owonikoko, AA Gal, CE Steuer, S Kim, RN Pillai, FR Khuri, SS Ramalingam, GL Sica	09/01/2016
Patient-derived xenografts faithfully replicated clinical outcome in a phase II co-clinical trial of arsenic trioxide in relapsed small cell lung cancer. Journal of translational medicine	TK Owonikoko, G Zhang, HS Kim, RM Stinson, R Bechara, C Zhang, Z Chen, NF Saba, S Pakkala, R Pillai, X Deng, SY Sun, MR Rossi, GL Sica, SS Ramalingam, FR Khuri	05/03/2016
Role of race in oncogenic driver prevalence and outcomes in lung adenocarcinoma: Results from the Lung Cancer Mutation Consortium. Cancer	CE Steuer, M Behera, L Berry, S Kim, M Rossi, G Sica, TK Owonikoko, BE Johnson, MG Kris, PA Bunn, FR Khuri, EB Garon, SS Ramalingam	03/01/2016
Clinical Validation and Implementation of a Targeted Next-Generation Sequencing Assay to Detect Somatic Variants in Non-Small Cell Lung, Melanoma, and Gastrointestinal Malignancies. The Journal of molecular diagnostics : JMD	KE Fisher, L Zhang, J Wang, GH Smith, S Newman, TM Schneider, RN Pillai, RR Kudchadkar, TK Owonikoko, SS Ramalingam, DH Lawson, KA Delman, BF El-Rayes, MM Wilson, HC Sullivan, AS Morrison, S Balci, NV Adsay, AA Gal, GL Sica, DF Saxe, KP Mann, CE Hill, FR Khuri, MR Rossi	03/01/2016
Metabolic Rewiring by Oncogenic BRAF V600E Links Ketogenesis Pathway to BRAF-MEK1 Signaling. Molecular cell	HB Kang, J Fan, R Lin, S Elf, Q Ji, L Zhao, L Jin, JH Seo, C Shan, JL Arbiser, C Cohen, D Brat, HM Miziorko, E Kim, O Abdel-Wahab, T Merghoub, S Fröhling, C Scholl, P Tamayo, DA Barbie, L Zhou, BP Pollack, K Fisher, RR Kudchadkar, DH Lawson, G Sica, M Rossi, S Lonial, HJ Khoury, FR Khuri, BH Lee, TJ Boggon, C He, S Kang, J Chen	08/06/2015
A Bystander Effect of Lung Cancer Chemotherapy on Chronic Echinococcal Disease. World journal of oncology	SD Bangaru, PE Kozarsky, DJ Lee, GL Sica, TK Owonikoko	08/01/2015
Small-Molecule Bcl2 BH4 Antagonist for Lung Cancer Therapy. Cancer cell	B Han, D Park, R Li, M Xie, TK Owonikoko, G Zhang, GL Sica, C Ding, J Zhou, AT Magis, ZG Chen, DM Shin, SS Ramalingam, FR Khuri, WJ Curran, X Deng	06/08/2015
A Translational, Pharmacodynamic, and Pharmacokinetic Phase IB Clinical Study of Everolimus in Resectable Non-Small Cell Lung Cancer. Clinical cancer research : an official journal of the American Association for Cancer Research	TK Owonikoko, SS Ramalingam, DL Miller, SD Force, GL Sica, J Mendel, Z Chen, A Rogatko, M Tighiouart, RD Harvey, S Kim, NF Saba, A Pickens, M Behera, RW Fu, MR Rossi, WF Auffermann, WE Torres, R Bechara, X Deng, SY Sun, H Fu, AA Gal, FR Khuri	04/15/2015
Anaplastic lymphoma kinase (ALK) gene alteration in signet ring cell carcinoma of the gastrointestinal tract. Therapeutic advances in medical oncology	OB Alese, BF El-Rayes, G Sica, G Zhang, D Alexis, FG La Rosa, M Varella-Garcia, Z Chen, MR Rossi, NV Adsay, FR Khuri, TK Owonikoko	03/01/2015
Poly (ADP) ribose polymerase enzyme inhibitor, veliparib, potentiates chemotherapy and radiation in vitro and in vivo in small cell lung cancer. Cancer medicine	TK Owonikoko, G Zhang, X Deng, MR Rossi, JM Switchenko, GH Doho, Z Chen, S Kim, S Strychor, SM Christner, J Beumer, C Li, P Yue, A Chen, GL Sica, SS Ramalingam, J Kowalski, FR Khuri, SY Sun	12/01/2014
Small-molecule Bax agonists for cancer therapy. Nature communications	M Xin, R Li, M Xie, D Park, TK Owonikoko, GL Sica, PE Corsino, J Zhou, C Ding, MA White, AT Magis, SS Ramalingam, WJ Curran, FR Khuri, X Deng	09/17/2014
Chemoprevention of head and neck cancer with celecoxib and erlotinib: results of a phase ib and pharmacokinetic study. Cancer prevention research (Philadelphia, Pa.)	NF Saba, SJ Hurwitz, SA Kono, CS Yang, Y Zhao, Z Chen, G Sica, S Müller, R Moreno-Williams, M Lewis, W Grist, AY Chen, CE Moore, TK Owonikoko, S Ramalingam, JJ Beitler, S Nannapaneni, HJ Shin, JR Grandis, FR Khuri, ZG Chen, DM Shin	03/01/2014
Class I HDACs are mediators of smoke carcinogen-induced stabilization of DNMT1 and serve as promising targets for chemoprevention of lung cancer. Cancer prevention research (Philadelphia, Pa.)	SA Brodie, G Li, A El-Kommos, H Kang, SS Ramalingam, M Behera, K Gandhi, J Kowalski, GL Sica, FR Khuri, PM Vertino, JC Brandes	03/01/2014
Disruption of STAT3 by niclosamide reverses radioresistance of human lung cancer. Molecular cancer therapeutics	S You, R Li, D Park, M Xie, GL Sica, Y Cao, ZQ Xiao, X Deng	03/01/2014
Synthetic curcumin analog UBS109 inhibits the growth of head and neck squamous cell carcinoma xenografts. Current cancer drug targets	S Zhu, TW Moore, N Morii, RB Howard, D Culver, RF Arrendale, P Reddy, TJ Evers, H Zhang, G Sica, ZG Chen, A Sun, H Fu, FR Khuri, DM Shin, JP Snyder, M Shoji	01/01/2014
A 22-year-old woman with bronchiectasis and a mediastinal mass. Chest	WR Hunt, JS Allam, G Sica, BP Little, S Veeraraghavan	10/01/2013
Niclosamide overcomes acquired resistance to erlotinib through suppression of STAT3 in non-small cell lung cancer. Molecular cancer therapeutics	R Li, Z Hu, SY Sun, ZG Chen, TK Owonikoko, GL Sica, SS Ramalingam, WJ Curran, FR Khuri, X Deng	10/01/2013
Recurrence of pulmonary carcinoid tumors after resection: implications for postoperative surveillance. The Annals of thoracic surgery	F Lou, I Sarkaria, C Pietanza, W Travis, MS Roh, G Sica, D Healy, V Rusch, J Huang	10/01/2013
Novel small-molecule inhibitors of Bcl-XL to treat lung cancer. Cancer research	D Park, AT Magis, R Li, TK Owonikoko, GL Sica, SY Sun, SS Ramalingam, FR Khuri, WJ Curran, X Deng	09/01/2013
Primary pericardial mesothelioma in a 19-year-old presenting as pericarditis. The Annals of thoracic surgery	MO Kayatta, SP Dineen, G Sica, JD Puskas, A Pickens	08/01/2013
RRM2 regulates Bcl-2 in head and neck and lung cancers: a potential target for cancer therapy. Clinical cancer research : an official journal of the American Association for Cancer Research	MA Rahman, AR Amin, D Wang, L Koenig, S Nannapaneni, Z Chen, Z Wang, G Sica, X Deng, ZG Chen, DM Shin	07/01/2013
Interruption of nuclear localization of ATBF1 during the histopathologic progression of head and neck squamous cell carcinoma. Head & neck	X Sun, J Li, G Sica, SQ Fan, Y Wang, Z Chen, S Muller, ZG Chen, X Fu, XY Dong, P Guo, DM Shin, JT Dong	07/01/2013
CHFR protein expression predicts outcomes to taxane-based first line therapy in metastatic NSCLC. Clinical cancer research : an official journal of the American Association for Cancer Research	RN Pillai, SA Brodie, GL Sica, Y Shaojin, G Li, DC Nickleach, L Yuan, VA Varma, D Bonta, JG Herman, MV Brock, MJ Ribeiro, SS Ramalingam, TK Owonikoko, FR Khuri, JC Brandes	03/15/2013
Chemoprevention of head and neck cancer by simultaneous blocking of epidermal growth factor receptor and cyclooxygenase-2 signaling pathways: preclinical and clinical studies. Clinical cancer research : an official journal of the American Association for Cancer Research	DM Shin, H Zhang, NF Saba, AY Chen, S Nannapaneni, AR Amin, S Müller, M Lewis, G Sica, S Kono, JC Brandes, WJ Grist, R Moreno-Williams, JJ Beitler, SM Thomas, Z Chen, HJ Shin, JR Grandis, FR Khuri, ZG Chen	03/01/2013
Survival analysis of patients with stage I non-small-cell lung cancer using clinical and DNA repair pathway expression variables. Clinical lung cancer	M Behera, JJ Heine, GL Sica, EE Fowler, H Tran, RW Fu, AA Gal, R Hermann, W Mayfield, FR Khuri, TK Owonikoko, SS Ramalingam	03/01/2013
Phase II study of docetaxel in combination with everolimus for second- or third-line therapy of advanced non-small-cell lung cancer. Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer	SS Ramalingam, TK Owonikoko, M Behera, J Subramanian, NF Saba, SA Kono, AA Gal, G Sica, RD Harvey, Z Chen, CM Klass, DM Shin, H Fu, SY Sun, R Govindan, FR Khuri	03/01/2013
Inhibition of STAT3 by niclosamide synergizes with erlotinib against head and neck cancer. PloS one	R Li, S You, Z Hu, ZG Chen, GL Sica, FR Khuri, WJ Curran, DM Shin, X Deng	01/01/2013
Unusual suspects: pulmonary opportunistic infections masquerading as tumor metastasis in a patient with adrenocorticotropic hormone-producing pancreatic neuroendocrine cancer. Therapeutic advances in medical oncology	RP Chowdry, C Bhimani, MA Delgado, DJ Lee, P Dayamani, GL Sica, TK Owonikoko	11/01/2012
Lung cancer staging: pathology issues. Seminars in diagnostic pathology	GL Sica, AA Gal	08/01/2012
Synthetic curcumin analog EF31 inhibits the growth of head and neck squamous cell carcinoma xenografts. Integrative biology : quantitative biosciences from nano to macro	S Zhu, TW Moore, X Lin, N Morii, A Mancini, RB Howard, D Culver, RF Arrendale, P Reddy, TJ Evers, H Zhang, G Sica, ZG Chen, A Sun, H Fu, FR Khuri, DM Shin, JP Snyder, M Shoji	06/01/2012
Rapamycin induces Bad phosphorylation in association with its resistance to human lung cancer cells. Molecular cancer therapeutics	Y Liu, SY Sun, TK Owonikoko, GL Sica, WJ Curran, FR Khuri, X Deng	01/01/2012
Metabolomic profiling reveals potential markers and bioprocesses altered in bladder cancer progression. Cancer research	N Putluri, A Shojaie, VT Vasu, SK Vareed, S Nalluri, V Putluri, GS Thangjam, K Panzitt, CT Tallman, C Butler, TR Sana, SM Fischer, G Sica, DJ Brat, H Shi, GS Palapattu, Y Lotan, AZ Weizer, MK Terris, SF Shariat, G Michailidis, A Sreekumar	12/15/2011

Awards

Dr. Sica has been named to the MilliPub Club, which recognizes current Emory University School of Medicine faculty who have published one or more individual papers throughout their careers that have garnered more than 1,000 citations.

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