Xiangyang Tang, PhD, DABR

Research Program

Discovery and Developmental Therapeutics
Phone Number

404-712-1869
Email Address

xiangyang.tang@emory.edu

Biography

Xiangyang Tang, PhD, DABR, is a professor in the Department of Radiology and Imaging Sciences at Emory University School of Medicine and serves as Director of the Laboratory of Translational Research in CT. Dr. Tang is is a member of the Discovery and Developmental Therapeutics Research Program at Winship Cancer Institute of Emory University.

With 19 patents and over 100 papers under his name, Dr. Tang is a leading researcher in CT imaging. He was a scientist in GE's Applied Science Lab (2001-2009) and made key contributions to its flagship CT products (Lightspeed VCT and Discovery CT750-HD). He is currently principal investigator of research funded by the Department of Defense and industry, and serves the community in scientific committees (RSNA Physics Subcommittee), study sections (NIH and DoD) and as an associate editor (Medical Physics).

Education

Dr. Tang received his PhD and MS from the University of Rochester in Rochester, New York.

Titles & Roles

Professor, Department of Radiology and Imaging Sciences

Emory University School of Medicine
Director, Laboratory of Translational Research in CT

Emory University School of Medicine

Research

By leveraging his experience in cone beam CT (CBDT), multi-detector CT (MDCT) and the latest phase contrast CT, Dr. Tang is conducting research to advance CT's contrast, spatial, spectral and temporal resolution to overcome the challenges imposed by clinical applications, e.g., early diagnosis of cancer and assessment of atherosclerotic plaque vulnerability. As an ABR-certified medical physicist in diagnostic medical physics, the reduction of radiation dose associated with CT is also within his research scope.

Publications

Title/Journal	Authors	Publication Date
Optimization-Based Image Reconstruction Regularized with Inter-Spectral Structural Similarity for Limited-Angle Dual-Energy Cone-Beam CT. ArXiv	J Peng, T Wang, H Xie, RLJ Qiu, CW Chang, J Roper, DS Yu, X Tang, X Yang	12/18/2024
Image-domain material decomposition for dual-energy CT using unsupervised learning with data-fidelity loss. Medical physics	J Peng, CW Chang, H Xie, RLJ Qiu, J Roper, T Wang, B Ghavidel, X Tang, X Yang	09/01/2024
Noise correlation and its impact on the performance of multi-material decomposition-based spectral imaging in photon-counting CT. Journal of applied clinical medical physics	X Tang, Y Ren, H Xie	01/01/2023
Photon-counting CT via interleaved/gapped spectral channels: Feasibility and imaging performance. Medical physics	X Tang, Y Ren, H Xie	03/01/2022
On the Conditioning of Spectral Channelization (Energy Binning) and Its Impact on Multi-Material Decomposition Based Spectral Imaging in Photon-Counting CT. IEEE transactions on bio-medical engineering	Y Ren, H Xie, W Long, X Yang, X Tang	09/01/2021
High through-plane resolution CT imaging with self-supervised deep learning. Physics in medicine and biology	H Xie, Y Lei, T Wang, Z Tian, J Roper, JD Bradley, WJ Curran, X Tang, T Liu, X Yang	07/14/2021
Principal Component Analysis in Projection and Image Domains-Another Form of Spectral Imaging in Photon-Counting CT. IEEE transactions on bio-medical engineering	H Xie, Y Ren, W Long, X Yang, X Tang	03/01/2021
On the conditioning of basis materials and its impact on multimaterial decomposition-based spectral imaging in photon-counting CT. Medical physics	X Tang, Y Ren	03/01/2021
CT-based multi-organ segmentation using a 3D self-attention U-net network for pancreatic radiotherapy. Medical physics	Y Liu, Y Lei, Y Fu, T Wang, X Tang, X Jiang, WJ Curran, T Liu, P Patel, X Yang	09/01/2020
CBCT-based synthetic CT generation using deep-attention cycleGAN for pancreatic adaptive radiotherapy. Medical physics	Y Liu, Y Lei, T Wang, Y Fu, X Tang, WJ Curran, T Liu, P Patel, X Yang	06/01/2020
Withdrawal: Distinct roles of Ape1 protein, an enzyme involved in DNA repair, in high or low linear energy transfer ionizing radiation-induced cell killing. The Journal of biological chemistry	H Wang, X Wang, G Chen, X Zhang, X Tang, D Park, FA Cucinotta, DS Yu, X Deng, WS Dynan, PW Doetsch, Y Wang	05/01/2020
Data sustained misalignment correction in microscopic cone beam CT via optimization under the Grangeat Epipolar consistency condition. Medical physics	S Luo, L Zheng, S Luo, N Gu, X Tang	02/01/2020
Impact of Overlying Personal Items on CT Dose with Use of Automated Tube Current Modulation-Pilot Investigation. Current problems in diagnostic radiology	TR Mulvey, X Tang, EA Krupinski, PK Mittal, CC Moreno	01/01/2020
Dosimetric study on learning-based cone-beam CT correction in adaptive radiation therapy. Medical dosimetry : official journal of the American Association of Medical Dosimetrists	T Wang, Y Lei, N Manohar, S Tian, AB Jani, HK Shu, K Higgins, A Dhabaan, P Patel, X Tang, T Liu, WJ Curran, X Yang	12/01/2019
Paired cycle-GAN-based image correction for quantitative cone-beam computed tomography. Medical physics	J Harms, Y Lei, T Wang, R Zhang, J Zhou, X Tang, WJ Curran, T Liu, X Yang	09/01/2019
Certification in Medical Physics Imaging, The Workforce and Training Models. Journal of the American College of Radiology : JACR	JA Nye, M Cuddy, T Ruckdeschel, N Jallow, S Dharmadhikari, X Tang, ME Mullins	03/01/2019
Development of an Academic-Private Collaborative Medical Physics Imaging Residency Training Model. Journal of the American College of Radiology : JACR	JA Nye, M Cuddy, T Ruckdeschel, N Jallow, S Dharmadhikari, X Tang, ME Mullins	03/01/2019
Optimal virtual monoenergetic image in "TwinBeam" dual-energy CT for organs-at-risk delineation based on contrast-noise-ratio in head-and-neck radiotherapy. Journal of applied clinical medical physics	T Wang, BB Ghavidel, JJ Beitler, X Tang, Y Lei, WJ Curran, T Liu, X Yang	02/01/2019
Learning-based CBCT correction using alternating random forest based on auto-context model. Medical physics	Y Lei, X Tang, K Higgins, J Lin, J Jeong, T Liu, A Dhabaan, T Wang, X Dong, R Press, WJ Curran, X Yang	02/01/2019
Prevalence and Severity of Off-Centering During Diagnostic CT: Observations From 57,621 CT scans of the Chest, Abdomen, and/or Pelvis. Current problems in diagnostic radiology	OO Akin-Akintayo, LF Alexander, R Neill, EA Krupinksi, X Tang, PK Mittal, WC Small, CC Moreno	01/01/2019
Content-oriented sparse representation (COSR) for CT denoising with preservation of texture and edge. Medical physics	H Xie, T Niu, S Tang, X Yang, N Kadom, X Tang	11/01/2018
On the data acquisition, image reconstruction, cone beam artifacts, and their suppression in axial MDCT and CBCT - A review. Medical physics	X Tang, EA Krupinski, H Xie, AE Stillman	07/17/2018
Optimization based beam-hardening correction in CT under data integral invariant constraint. Physics in medicine and biology	S Tang, K Huang, Y Cheng, X Mou, X Tang	07/02/2018
Interior tomography in microscopic CT with image reconstruction constrained by full field of view scan at low spatial resolution. Physics in medicine and biology	S Luo, T Shen, Y Sun, J Li, G Li, X Tang	03/26/2018
Improving Image Quality of Cone-Beam CT Using Alternating Regression Forest. Proceedings of SPIE--the International Society for Optical Engineering	Y Lei, X Tang, K Higgins, T Wang, T Liu, A Dhabaan, H Shim, WJ Curran, X Yang	02/01/2018
Optimization of data acquisition in axial CT under the framework of sampling on lattice for suppression of aliasing artifacts with algorithmic detector interlacing. Medical physics	H Xie, X Tang	12/01/2017
A Patch-based CBCT Scatter Artifact Correction Using Prior CT. Proceedings of SPIE--the International Society for Optical Engineering	X Yang, T Liu, X Dong, X Tang, E Elder, WJ Curran, A Dhabaan	02/01/2017
Reducing radiation dose in grating based x-ray phase contrast CT with twin-peaks in its phase stepping curves. Medical physics	H Xie, W Cai, L Yang, H Mao, X Tang	11/01/2016
Grating-based x-ray differential phase contrast imaging with twin peaks in phase-stepping curves-phase retrieval and dewrapping. Medical physics	Y Yang, H Xie, W Cai, H Mao, X Tang	06/01/2016
A nanocomposite of Au-AgI core/shell dimer as a dual-modality contrast agent for x-ray computed tomography and photoacoustic imaging. Medical physics	A Orza, Y Yang, T Feng, X Wang, H Wu, Y Li, L Yang, X Tang, H Mao	01/01/2016
3D fusion of LV venous anatomy on fluoroscopy venograms with epicardial surface on SPECT myocardial perfusion images for guiding CRT LV lead placement. JACC. Cardiovascular imaging	W Zhou, X Hou, M Piccinelli, X Tang, L Tang, K Cao, EV Garcia, J Zou, J Chen	12/01/2014
Complex dark-field contrast and its retrieval in x-ray phase contrast imaging implemented with Talbot interferometry. Medical physics	Y Yang, X Tang	10/01/2014
Variability of MDCT dose due to technologist performance: impact of posteroanterior versus anteroposterior localizer image and table height with use of automated tube current modulation. AJR. American journal of roentgenology	PA Harri, CC Moreno, RC Nelson, N Fani, WC Small, PA Duong, X Tang, KE Applegate	08/01/2014
Radial differential interior tomography and its image reconstruction with differentiated backprojection and projection onto convex sets. Medical physics	S Tang, X Tang	09/01/2013
The second-order differential phase contrast and its retrieval for imaging with x-ray Talbot interferometry. Medical physics	Y Yang, X Tang	12/01/2012
A system for seismocardiography-based identification of quiescent heart phases: implications for cardiac imaging. IEEE transactions on information technology in biomedicine : a publication of the IEEE Engineering in Medicine and Biology Society	CA Wick, JJ Su, JH McClellan, O Brand, PT Bhatti, AL Buice, AE Stillman, X Tang, S Tridandapani	09/01/2012
Statistical CT noise reduction with multiscale decomposition and penalized weighted least squares in the projection domain. Medical physics	S Tang, X Tang	09/01/2012
Characterization of imaging performance in differential phase contrast CT compared with the conventional CT: spectrum of noise equivalent quanta NEQ(k). Medical physics	X Tang, Y Yang, S Tang	07/01/2012
Practical interior tomography with radial Hilbert filtering and a priori knowledge in a small round area. Journal of X-ray science and technology	S Tang, Y Yang, X Tang	01/01/2012
The mathematical equivalence of consistency conditions in the divergent-beam computed tomography. Journal of X-ray science and technology	S Tang, Q Xu, X Mou, X Tang	01/01/2012
Characterization of imaging performance in differential phase contrast CT compared with the conventional CT--noise power spectrum NPS(k). Medical physics	X Tang, Y Yang, S Tang	07/01/2011
Patient size compensated automatic tube current modulation in multi-detector row CT of the abdomen and pelvis. Academic radiology	J Li, UK Udayasankar, X Tang, TL Toth, WC Small, MK Kalra	02/01/2011
An optimal contrast dose indicator for the determination of hepatic enhancement in abdominal multidetector computed tomography: comparison of patient attenuation indicator with total body weight and body mass index. Journal of computer assisted tomography	J Li, UK Udayasankar, X Tang, J Carew, TL Toth, WC Small	01/01/2010
Enhancement of in-plane spatial resolution in volumetric Computed Tomography with focal spot wobbling - overcoming the constraint on number of projection views per gantry rotation. Journal of X-ray science and technology	X Tang, S Narayanan, J Hsieh, JD Pack, SM Mcolash, P Sainath, RA Nilsen, B Taha	01/01/2010