Douglas Walker, PhD
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Research Program
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Email Address
Biography
Douglas Walker, PhD, is an Associate Professor in the Gangarosa Department of Environmental Health at Emory University and adjunct Assistant Professor at Utrecht University. Before joining Emory University, Dr. Walker was an Assistant Professor in the Department of Environmental Medicine and Public Health at the Icahn School of Medicine in New York. He is an environmental engineer and analytical chemist with training in metabolomics and developing EWAS (exposome-wide association study) methodologies for environmental health and precision medicine research.
Dr. Walker leads the Comprehensive Laboratory for Untargeted Exposome Science (CLUES), which was established to provide high-quality, untargeted screening of biological samples for nutrition, precision medicine and environmental health research.
Dr. Walker is a member of the Cancer Prevention and Control Research Program at Winship Cancer Institute.
Education
Dr. Walker earned his PhD in Environmental and Water Resources Engineering from Tufts University.
Titles & Roles
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Associate Professor, Department of Environmental HealthRollins School of Public Health, Emory University
Research
Dr. Walker’s research focuses on continued development and application of advanced analytical strategies for measuring the occurrence, distribution and magnitude of previously unidentified environmental exposures and assisting in delineating the mechanisms underlying environment-related diseases in humans. The approaches he developed show it is possible to measure over 100,000 chemical signals that include exposure biomarkers, nutrients, dietary chemicals and associated biological response in a high-throughput and cost-effective manner, establishing a foundation for operationalizing the exposome framework for precision medicine. Ongoing research projects are now focused on using high-throughput exposome methods to establish disease-exposome atlases, and development of methods for measuring biomarkers of complex exposures of emerging concern, including microplastics, e-waste and polyfluorinated chemicals.
Publications
| Title/Journal | Authors | Publication Date |
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Beyond the Surface: Mapping DDE's Metabolic Footprint on Adolescent Obesity. Environmental health perspectives |
Z Li, S Pan, BO Baumert, JC Chen, JA Goodrich, H Wang, S Rock, J Ryder, D Valvi, T Jenkins, S Sisley, X Lin, SM Bartell, TH Inge, S Xanthakos, B McNeil, AR Robuck, CE Mullins, SP Eckel, RS McConnell, MA La Merrill, DI Walker, DV Conti, L Chatzi | 06/03/2025 |
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Prenatal PFAS exposures and cardiometabolic health in middle childhood in the MIREC cohort. Environmental research |
AJ Fossa, AM Hall, GD Papandonatos, TE Arbuckle, J Ashley-Martin, MM Borghese, J Bruin, A Chen, M Fisher, JE Krzeczkowski, BP Lanphear, AJ MacFarlane, KE Manz, KM Morrison, Y Oulhote, J Palaniyandi, MR Palmert, KD Pennell, AM Vuong, DI Walker, HA Weiler, JM Braun | 06/01/2025 |
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Environmental science & technology |
S Pan, Z Li, DI Walker, BO Baumert, H Wang, JA Goodrich, S Rock, TH Inge, TM Jenkins, S Sisley, SM Bartell, S Xanthakos, X Lin, B McNeil, AR Robuck, CE Mullins, MA La Merill, E Garcia, MT Aung, SP Eckel, R McConnell, DV Conti, JR Ryder, L Chatzi | 03/11/2025 |
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Differential metabolic profiles by Hispanic ethnicity among male Tucson firefighters. Metabolomics : Official journal of the Metabolomic Society |
T Liu, MA Furlong, JM Snider, MM Tfaily, C Itson, SC Beitel, JJ Gulotta, K Parsawar, K Keck, J Galligan, DI Walker, JM Goodrich, JL Burgess | 03/06/2025 |
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Research square |
BO Baumert, AC Maretti-Mira, DI Walker, Z Li, N Stratakis, H Wang, Y Zhao, FC Fischer, Q Jia, D Valvi, SM Bartell, C Chen, T Inge, J Ryder, T Jenkins, S Sisley, S Xanthakos, DE Kleiner, R Kohli, S Rock, SP Eckel, MA La Merrill, MM Aung, MP Salomon, R McConnell, J Goodrich, DV Conti, L Golden-Mason, L Chatzi | 03/04/2025 |
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Environmental pollution (Barking, Essex : 1987) |
WB Patterson, ND Young, EA Holzhausen, F Lurmann, D Liang, DI Walker, DP Jones, J Liao, Z Chen, DV Conti, L Chatzi, JA Goodrich, TL Alderete | 03/01/2025 |
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Metabolomics : Official journal of the Metabolomic Society |
D He, Q Yan, K Uppal, DI Walker, DP Jones, B Ritz, JE Heck | 02/20/2025 |
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Molecular profiling of neuronal extracellular vesicles reveals brain tissue specific signals. medRxiv : the preprint server for health sciences |
V Kalia, G Jackson, RJ Dominguez, B Pinto-Pacheco, T Bloomquist, J Furnari, M Banu, O Volpert, KE Manz, DI Walker, KD Pennell, PD Canoll, JN Bruce, E Eitan, H Wu, AA Baccarelli | 01/25/2025 |
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The need for a cancer exposome atlas: a scoping review. JNCI cancer spectrum |
AS Young, CE Mullins, N Sehgal, RCH Vermeulen, PM Kolijn, J Vlaanderen, ML Rahman, BM Birmann, D Barupal, Q Lan, N Rothman, DI Walker | 01/03/2025 |
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American journal of human biology : the official journal of the Human Biology Council |
C Chaney, L Mansilla, M Kubica, B Pinto-Pacheco, K Dunn, V Bertacchi, DI Walker, C Valeggia | 01/01/2025 |
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Annual review of pharmacology and toxicology |
K Shao, R Zou, Z Zhang, LDB Mandemaker, S Timbie, RD Smith, AM Durkin, HM Dusza, F Meirer, BM Weckhuysen, TL Alderete, R Vermeulen, DI Walker | 01/01/2025 |
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Environmental research |
S Li, JA Goodrich, E Costello, DI Walker, C Cardenas-Iniguez, JC Chen, TL Alderete, D Valvi, S Rock, SP Eckel, R McConnell, FD Gilliland, J Wilson, B MacDonald, DV Conti, AL Smith, DL McCurry, AE Childress, AM Simpson, L Golden-Mason, AC Maretti-Mira, Z Chen, MI Goran, M Aung, L Chatzi | 01/01/2025 |
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Environmental epidemiology (Philadelphia, Pa.) |
RL Criswell, JA Bauer, BC Christensen, J Meijer, LA Peterson, CA Huset, DI Walker, MR Karagas, ME Romano | 12/01/2024 |
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The Science of the total environment |
HE Hampson, S Li, DI Walker, H Wang, Q Jia, S Rock, E Costello, P Bjornstad, L Pyle, J Nelson, FD Gilliland, Z Chen, M Aung, L Chatzi, DV Conti, TL Alderete, JA Goodrich | 12/01/2024 |
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Environmental research |
Y Li, BO Baumert, N Stratakis, JA Goodrich, H Wu, SH Liu, H Wang, E Beglarian, SM Bartell, SP Eckel, D Walker, D Valvi, MA La Merrill, TH Inge, T Jenkins, JR Ryder, S Sisley, R Kohli, SA Xanthakos, M Vafeiadi, A Margetaki, T Roumeliotaki, M Aung, R McConnell, A Baccarelli, D Conti, L Chatzi | 10/15/2024 |
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JMIR research protocols |
AM Durkin, R Zou, JM Boucher, MS Boyles, J van Boxel, M Bustamante, EA Christopher, P Dadvand, HM Dusza, M van Duursen, MM Forsberg, KS Galea, J Legler, LD Mandemaker, F Meirer, J Muncke, TS Nawrot, P Přibylová, AR Robuck, ND Saenen, BM Scholz-Böttcher, K Shao, M Vrijheid, DI Walker, L Zimmermann, LM Zoutendijk, V Lenters, R Vermeulen | 10/08/2024 |
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Association of per- and polyfluoroalkyl substances with the antioxidant bilirubin across pregnancy. Free radical biology & medicine |
KR Taibl, AL Dunlop, MR Smith, DI Walker, PB Ryan, P Panuwet, EJ Corwin, K Kannan, DP Jones, CJ Marsit, Y Tan, D Liang, SM Eick, DB Barr | 10/01/2024 |
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International journal of cancer |
ML Rahman, XO Shu, DP Jones, W Hu, BT Ji, B Blechter, JYY Wong, Q Cai, G Yang, YT Gao, W Zheng, N Rothman, D Walker, Q Lan | 08/01/2024 |
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High-Resolution Mass Spectrometry for Human Exposomics: Expanding Chemical Space Coverage. Environmental science & technology |
Y Lai, JP Koelmel, DI Walker, EJ Price, S Papazian, KE Manz, D Castilla-Fernández, JA Bowden, V Nikiforov, A David, V Bessonneau, B Amer, S Seethapathy, X Hu, EZ Lin, A Jbebli, BR McNeil, D Barupal, M Cerasa, H Xie, V Kalia, R Nandakumar, R Singh, Z Tian, P Gao, Y Zhao, J Froment, P Rostkowski, S Dubey, K Coufalíková, H Seličová, H Hecht, S Liu, HH Udhani, S Restituito, KM Tchou-Wong, K Lu, JW Martin, B Warth, KJ Godri Pollitt, J Klánová, O Fiehn, TO Metz, KD Pennell, DP Jones, GW Miller | 07/23/2024 |
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Environmental research |
BO Baumert, H Wang, S Samy, SK Park, CN Lam, K Dunn, B Pinto-Pacheco, D Walker, J Landero, D Conti, L Chatzi, H Hu, JA Goodrich | 07/01/2024 |
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Untargeted serum metabolic profiling of diabetes mellitus among Parkinson's disease patients. NPJ Parkinson's disease |
S Li, Y Lin, D Jones, DI Walker, A Duarte Folle, I Del Rosario, Y Yu, K Zhang, AM Keener, J Bronstein, B Ritz, KC Paul | 05/10/2024 |
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Obesity (Silver Spring, Md.) |
B Rubbo, Z Li, P Tachachartvanich, BO Baumert, H Wang, S Pan, S Rock, JR Ryder, T Jenkins, S Sisley, X Lin, S Bartell, TH Inge, S Xanthakos, B McNeil, AR Robuck, MA La Merrill, DI Walker, DV Conti, R McConnell, SP Eckel, L Chatzi | 05/01/2024 |
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Exposure to per- and polyfluoroalkyl substances and high-throughput proteomics in Hispanic youth. Environment international |
JC Chen, JA Goodrich, DI Walker, J Liao, E Costello, TL Alderete, D Valvi, H Hampson, S Li, BO Baumert, S Rock, DP Jones, SP Eckel, R McConnell, FD Gilliland, MT Aung, DV Conti, Z Chen, L Chatzi | 04/01/2024 |
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Environment international |
HE Hampson, E Costello, DI Walker, H Wang, BO Baumert, D Valvi, S Rock, DP Jones, MI Goran, FD Gilliland, DV Conti, TL Alderete, Z Chen, L Chatzi, JA Goodrich | 03/01/2024 |
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Environmental research |
E Beglarian, E Costello, DI Walker, H Wang, TL Alderete, Z Chen, D Valvi, BO Baumert, S Rock, B Rubbo, MT Aung, FD Gilliland, MI Goran, DP Jones, R McConnell, SP Eckel, DV Conti, JA Goodrich, L Chatzi | 03/01/2024 |
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Environmental research |
JG Debertin, EA Holzhausen, DI Walker, BP Pacheco, KA James, TL Alderete, L Corlin | 02/15/2024 |
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Paediatric and perinatal epidemiology |
D He, X Huang, OA Arah, DI Walker, DP Jones, B Ritz, JE Heck | 02/01/2024 |
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Metabolomic Effects of Folic Acid Supplementation in Adults: Evidence from the FACT Trial. The Journal of nutrition |
I Martinez-Morata, H Wu, M Galvez-Fernandez, V Ilievski, T Bottiglieri, MM Niedzwiecki, J Goldsmith, DP Jones, MA Kioumourtzoglou, B Pierce, DI Walker, MV Gamble | 02/01/2024 |
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Proteomic and Metabolomic Signatures of Diet Quality in Young Adults. Nutrients |
E Costello, JA Goodrich, WB Patterson, DI Walker, JC Chen, BO Baumert, S Rock, FD Gilliland, MI Goran, Z Chen, TL Alderete, DV Conti, L Chatzi | 01/31/2024 |
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World journal of gastroenterology |
YJ Li, BO Baumert, N Stratakis, JA Goodrich, HT Wu, JX He, YQ Zhao, MT Aung, HX Wang, SP Eckel, DI Walker, D Valvi, MA La Merrill, JR Ryder, TH Inge, T Jenkins, S Sisley, R Kohli, SA Xanthakos, AA Baccarelli, R McConnell, DV Conti, L Chatzi | 01/28/2024 |
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Environmental science & technology |
Y Zhao, J Meijer, DI Walker, J Kim, L Portengen, DP Jones, F Saberi Hosnijeh, J Vlaanderen, R Vermeulen | 01/09/2024 |
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Diabetes care |
JA Goodrich, H Wang, DI Walker, X Lin, X Hu, TL Alderete, Z Chen, D Valvi, BO Baumert, S Rock, K Berhane, FD Gilliland, MI Goran, DP Jones, DV Conti, L Chatzi | 01/01/2024 |
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Neonatal per- and polyfluoroalkyl substance exposure in relation to retinoblastoma. Environmental research |
Y Chen, KC Paul, DI Walker, DP Jones, X Wang, BR Ritz, JE Heck | 01/01/2024 |
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Environmental science & technology |
AM Hall, E Fleury, GD Papandonatos, JP Buckley, KM Cecil, A Chen, BP Lanphear, K Yolton, DI Walker, KD Pennell, JM Braun, KE Manz | 12/26/2023 |
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Molecular neurodegeneration |
KC Paul, K Zhang, DI Walker, J Sinsheimer, Y Yu, C Kusters, I Del Rosario, AD Folle, AM Keener, J Bronstein, DP Jones, B Ritz | 12/19/2023 |
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The neonatal blood spot metabolome in retinoblastoma. EJC paediatric oncology |
Q Yan, D He, DI Walker, K Uppal, X Wang, HT Orimoloye, DP Jones, BR Ritz, JE Heck | 12/01/2023 |
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Scientific reports |
MA Furlong, T Liu, JM Snider, MM Tfaily, C Itson, S Beitel, K Parsawar, K Keck, J Galligan, DI Walker, JJ Gulotta, JL Burgess | 11/27/2023 |