Peng Jin, PhD

Research Program

Cell and Molecular Biology
Phone Number

404-727-3729
Email Address

peng.jin@emory.edu

Biography

Peng Jin, PhD, serves as professor and chair in the Department of Human Genetics at Emory University School of Medicine. Dr. Jin is a fellow of the American Association for the Advancement of Science. He is a member of the Cell and Molecular Biology Research Program at Winship Cancer Institute of Emory University.

Education

Dr. Peng Jin received his doctorate degree in Molecular and Developmental Biology from Cincinnati Children’s Hospital/University of Cincinnati and completed postdoctoral training at Emory University.

Titles & Roles

Professor and Chair, Department of Human Genetics

Emory University School of Medicine

Research

Dr. Jin's research philosophy combines various disciplines (biochemistry, genetics, chemistry, human genetics/genomics, and bioinformatics) to understand the functions and mechanisms of epigenetics and noncoding RNAs in neurodevelopmental and neurodegenerative disorders.

Grants

View Grants

Grant Number	Title
1R35NS111602-01	Dynamic DNA Modifications in Brain and Diseases
5R01AG078937-04	Elucidating the Roles of Transposable Elements in Alzheimer's and related dementias
5R35NS111602-02	Dynamic DNA Modifications in Brain and Diseases
5R35NS111602-03	Dynamic DNA Modifications in Brain and Diseases
5R35NS111602-04	Dynamic DNA Modifications in Brain and Diseases
5R35NS111602-05	Dynamic DNA Modifications in Brain and Diseases
5R35NS111602-06	Dynamic DNA Modifications in Brain and Diseases
5R35NS111602-07	Dynamic DNA Modifications in Brain and Diseases

Publications

Dr. Jin is the recipient of Beckman Young Investigator Award, Basil O'Connor Scholar Research Award, Alfred P. Sloan Research Fellow in Neuroscience, and NARSAD Independent Investigator Award.

Title/Journal	Authors	Publication Date
Integrative transcriptome-wide association analyses reveal PRKCG-linked GABAergic dysfunction in Fragile X-associated tremor/ataxia syndrome Nature Communications	Y Jin, Y Cao, W Ma, R Li, Y Li, Y Kang, J Huang, MP Epstein, X Guo, J Lim, N Rivera, Y Zhou, Z Wen, EG Allen, P Jin	01/08/2026
Multi-region m6A epitranscriptome profiling of the human brain reveals spatial and temporal variation and enrichment of disease-associated loci Nature Neuroscience	AM Shafik, Y Peng, Z Zhang, C Chang, P Wang, J Lim, H Song, C He, M Chen, P Jin	12/09/2025
Buried Treasure? Overlooked and Newly Discovered Evolutionary Contributions to Human Brain Diseases Annals of Neurology	NJ Diederich, M Brüne, JS Allen, N Bender, E Bruner, JP Changeux, C Corrado, O Dolgova, A Grünewald, G Konopka, P Jin, R Lemon, G Levy, P Magistretti, MJ Rantala, KS Rockland, R Sullivan, A Swanepoel, T Uchihara, K Amunts, CG Goetz	09/18/2025
Epitranscriptomic dysregulation in neurodegenerative diseases and its implications for disease pathology and mechanisms Neurochemistry International	AM Shafik, P Jin	08/21/2025
Striatal GluN2A gene suppression reduces L-DOPA-induced abnormal involuntary movements in parkinsonian rats Neuropharmacology	T Yabumoto, BA Kochoian, S Coletta, O Laur, X Huang, CA Bure, C Ware, P Jin, SF Traynelis, SM Papa	07/29/2025
NKX2-1 drives neuroendocrine transdifferentiation of prostate cancer via epigenetic and 3D chromatin remodeling Nature Genetics	X Lu, V Keo, I Cheng, W Xie, G Gritsina, J Wang, L Lu, CK Shiau, Y He, Q Jin, P Jin, MG Sanda, VG Corces, N Altemose, R Gao, JC Zhao, J Yu	07/21/2025
scMultiMap: Cell-type-specific mapping of enhancers and target genes from single-cell multimodal data Nature Communications	C Su, D Lee, P Jin, J Zhang	04/26/2025
Modulating CCTG repeat expansion toxicity in DM2 Drosophila model through TDP1 inhibition EMBO Molecular Medicine	Y Zhu, S Xiao, X Guan, H Deng, L Ai, K Fan, J Xue, G Li, X Bi, Q Xiao, Y Huang, L Jiang, W Huang, P Jin, R Duan	03/25/2025
Brain 5-hydroxymethylcytosine alterations are associated with Alzheimer’s disease neuropathology Nature Communications	J Zhao, T Gu, C Gao, G Miao, H Palma-Gudiel, L Yu, J Yang, Y Wang, Y Li, J Lim, R Li, B Yao, H Wu, JA Schneider, N Seyfried, F Grodstein, PL De Jager, P Jin, DA Bennett	03/22/2025
pTDP-43 levels correlate with cell type–specific molecular alterations in the prefrontal cortex of C9orf72 ALS/FTD patients Proceedings of the National Academy of Sciences	HV Wang, JF Xiang, C Yuan, AM Veire, TF Gendron, ME Murray, MG Tansey, J Hu, M Gearing, JD Glass, P Jin, VG Corces, ZT McEachin	02/25/2025
Whole-genome bisulfite sequencing of cell-free DNA unveils age-dependent and ALS-associated methylation alterations Cell & Bioscience	Y Jin, KN Conneely, W Ma, RK Naviaux, T Siddique, EG Allen, S Guingrich, RM Pascuzzi, P Jin	02/20/2025
High-Sensitivity Fluorescence-Based Detection of Reverse Transcriptase Read-Through of GC-Rich Short Tandem Repeat RNA Analytical Chemistry	W Qiu, C Hazard, Y Li, P Jin, H Zhou	02/13/2025
Epigenetic remodeling and 3D chromatin reorganization governed by NKX2-1 drive neuroendocrine prostate cancer bioRxiv (Cold Spring Harbor Laboratory)	X Lu, V Keo, I Cheng, W Xie, G Gritsina, J Wang, Q Jin, P Jin, F Yue, MG Sanda, V Corces, N Altemose, JC Zhao, J Yu	12/07/2024
Transcription Factor-Wide Association Studies to Identify Functional SNPs in Alzheimer's Disease Journal of Neuroscience	J Dunn, C Moore, NS Kim, T Gao, Z Cheng, P Jin, GL Ming, J Qian, Y Su, H Song, H Zhu	12/02/2024
Cell-type-specific mapping of enhancers and target genes from single-cell multimodal data bioRxiv (Cold Spring Harbor Laboratory)	C Su, D Lee, P Jin, J Zhang	09/26/2024
Deep5hmC: predicting genome-wide 5-hydroxymethylcytosine landscape via a multimodal deep learning model Bioinformatics	X Ma, SR Thela, F Zhao, B Yao, Z Wen, P Jin, J Zhao, L Chen	08/28/2024
Omega-3 reverses the metabolic and epigenetically regulated placental phenotype acquired from preconceptional and peri-conceptional exposure to air pollutants The Journal of Nutritional Biochemistry	A Ganguly, S Ghosh, P Jin, M Wadehra, SU Devaskar	08/08/2024
Decoding the role of DNA methylation in allergic diseases: from pathogenesis to therapy Cell & Bioscience	R Han, D Zhu, J Sha, B Zhao, P Jin, C Meng	07/04/2024
Epigenetic modifications of DNA and RNA in Alzheimer’s disease Frontiers in Molecular Neuroscience	P Martinez-Feduchi, P Jin, B Yao	04/25/2024
Bridging the gap: R-loop mediated genomic instability and its implications in neurological diseases Epigenomics	KR Westover, P Jin, B Yao	03/26/2024
Deep5hmC: Predicting genome-wide 5-Hydroxymethylcytosine landscape via a multimodal deep learning model bioRxiv (Cold Spring Harbor Laboratory)	X Ma, SR Thela, F Zhao, B Yao, Z Wen, P Jin, J Zhao, L Chen	03/06/2024
Characterization and visualization of tandem repeats at genome scale Nature Biotechnology	E Dolzhenko, A English, H Dashnow, G De Sena Brandine, T Mokveld, WJ Rowell, C Karniski, Z Kronenberg, MC Danzi, WA Cheung, C Bi, E Farrow, A Wenger, KP Chua, V Martínez-Cerdeño, TD Bartley, P Jin, DL Nelson, S Zuchner, T Pastinen, AR Quinlan, FJ Sedlazeck, MA Eberle	01/02/2024
Transition of allele-specific DNA hydroxymethylation at regulatory loci is associated with phenotypic variation in monozygotic twins discordant for psychiatric disorders BMC Medicine	J Ye, Z Huang, Q Li, Z Li, Y Lan, Z Wang, C Ni, X Wu, T Jiang, Y Li, Q Yang, J Lim, CY Ren, M Jiang, S Li, P Jin, JH Chen, C Zhao	12/12/2023
Lowering Hippocampal miR-29a Expression Slows Cognitive Decline and Reduces Beta-Amyloid Deposition in 5×FAD Mice Molecular Neurobiology	Z Mei, J Liu, JP Schroeder, D Weinshenker, DM Duong, NT Seyfried, Y Li, P Jin, AP Wingo, TS Wingo	11/21/2023
FMRP phosphorylation modulates neuronal translation through YTHDF1 Molecular Cell	Z Zou, J Wei, Y Chen, Y Kang, H Shi, F Yang, Z Shi, S Chen, Y Zhou, C Sepich-Poore, X Zhuang, X Zhou, H Jiang, Z Wen, P Jin, C Luo, C He	11/09/2023
Insight and Recommendations for Fragile X-Premutation-Associated Conditions from the Fifth International Conference on FMR1 Premutation Cells	F Tassone, D Protic, EG Allen, AD Archibald, A Baud, TW Brown, DB Budimirovic, J Cohen, B Dufour, R Eiges, N Elvassore, LV Gabis, SJ Grudzien, DA Hall, D Hessl, A Hogan, JE Hunter, P Jin, P Jiraanont, J Klusek, RF Kooy, CM Kraan, C Laterza, A Lee, K Lipworth, M Losh, D Loesch, R Lozano, MR Mailick, A Manolopoulos, V Martinez-Cerdeno, Y McLennan, RM Miller, FAM Montanaro, MW Mosconi, SN Potter, M Raspa, SM Rivera, K Shelly, PK Todd, K Tutak, JY Wang, A Wheeler, TI Winarni, M Zafarullah, RJ Hagerman	09/21/2023
Lowering hippocampal miR-29a expression slows cognitive decline and reduces beta-amyloid deposition in 5xFAD mice Research Square	Z Mei, J Liu, JP Schroeder, D Weinshenker, DM Duong, NT Seyfried, Y Li, P Jin, AP Wingo, TS Wingo	08/16/2023
Role of TET1-mediated epigenetic modulation in Alzheimer's disease Neurobiology of Disease	MJ Armstrong, Y Jin, SM Vattathil, Y Huang, JP Schroeder, DA Bennet, ZS Qin, TS Wingo, P Jin	08/08/2023
Editorial: Non-canonical nucleic acid structures, functions and their applications for understanding human genetic diseases Frontiers in Genetics	R Satange, P Jin, MH Hou, AB Rode	04/05/2023
Dysregulation of Prefrontal Oligodendrocyte Lineage Cells Across Mouse Models of Adversity and Human Major Depressive Disorder bioRxiv (Cold Spring Harbor Laboratory)	S Sharma, W Ma, KJ Ressler, T Anderson, DC Li, P Jin, SL Gourley, Z Qin	03/10/2023
Age-Dependent Dysregulation of APP in Neuronal and Skin Cells from Fragile X Individuals Cells	G Cencelli, L Pacini, A De Luca, I Messia, A Gentile, Y Kang, V Nobile, E Tabolacci, P Jin, MG Farace, C Bagni	02/27/2023
MicroRNA-650 Regulates the Pathogenesis of Alzheimer’s Disease Through Targeting Cyclin-Dependent Kinase 5 Molecular Neurobiology	L Lin, X Liu, X Cheng, Y Li, M Gearing, A Levey, X Huang, Y Li, P Jin, X Li	01/19/2023
pTDP-43 levels correlate with cell type specific molecular alterations in the prefrontal cortex of C9orf72 ALS/FTD patients bioRxiv (Cold Spring Harbor Laboratory)	HV Wang, JF Xiang, C Yuan, AM Veire, TF Gendron, ME Murray, MG Tansey, J Hu, M Gearing, JD Glass, P Jin, VG Corces, ZT McEachin	01/13/2023
Highly synchronized cortical circuit dynamics mediate spontaneous pain in mice Journal of Clinical Investigation	W Ding, L Fischer, Q Chen, Z Li, L Yang, Z You, K Hu, X Wu, X Zhou, W Chao, P Hu, TM Dagnew, DM Dubreuil, S Wang, S Xia, C Bao, S Zhu, L Chen, C Wang, B Wainger, P Jin, J Mao, G Feng, MT Harnett, S Shen	01/05/2023
Analyzing mRNA Epigenetic Sequencing Data with TRESS Methods in molecular biology	Z Guo, AM Shafik, P Jin, Z Wu, H Wu	01/01/2023
Recruitment of CTCF to an Fto enhancer is responsible for transgenerational inheritance of BPA-induced obesity Proceedings of the National Academy of Sciences	YH Jung, HV Wang, D Ruiz, BJ Bixler, H Linsenbaum, JF Xiang, S Forestier, AM Shafik, P Jin, VG Corces	12/05/2022
Expression of expanded GGC repeats within NOTCH2NLC causes behavioral deficits and neurodegeneration in a mouse model of neuronal intranuclear inclusion disease Science Advances	Q Liu, K Zhang, Y Kang, Y Li, P Deng, Y Li, Y Tian, Q Sun, Y Tang, K Xu, Y Zhou, JL Wang, J Guo, JD Li, K Xia, Q Meng, EG Allen, Z Wen, Z Li, H Jiang, L Shen, R Duan, B Yao, B Tang, P Jin, Y Pan	11/23/2022
Differential RNA methylation analysis for MeRIP-seq data under general experimental design Bioinformatics	Z Guo, AM Shafik, P Jin, H Wu	09/05/2022
Fine‐mapping and replication of EWAS loci harboring putative epigenetic alterations associated with AD neuropathology in a large collection of human brain tissue samples Alzheimer s & Dementia	H Palma-Gudiel, L Yu, Z Huo, J Yang, Y Wang, T Gu, C Gao, PL De Jager, P Jin, DA Bennett, J Zhao	08/12/2022
Cell type-specific DNA methylome signatures reveal epigenetic mechanisms for neuronal diversity and neurodevelopmental disorder Human Molecular Genetics	Y Jin, K Su, HE Kong, W Ma, Z Wang, Y Li, R Li, EG Allen, H Wu, P Jin	08/10/2022
Descriptive analysis of seizures and comorbidities associated with fragile X syndrome Molecular Genetics & Genomic Medicine	I Albizua, K Charen, L Shubeck, A Talboy, E Berry-Kravis, WE Kaufmann, JL Stallworth, KT Drazba, CA Erickson, JA Sweeney, N Tartaglia, SF Warren, R Hagerman, SL Sherman, ST Warren, P Jin, EG Allen	07/18/2022
Altered hydroxymethylome in the substantia nigra of Parkinson’s disease Human Molecular Genetics	S Min, Q Xu, L Qin, Y Li, Z Li, C Chen, H Wu, J Han, X Zhu, P Jin, B Tang	06/04/2022
A homozygous exonic variant leading to exon skipping in ABCC8 as the cause of severe congenital hyperinsulinism American Journal of Medical Genetics Part A	JV Reyes Diaz, Y Jin, K Garber, KM Cossen, Y Li, P Jin, H Li, JN Ham	05/27/2022
Identification of PSMB5 as a genetic modifier of fragile X–associated tremor/ataxia syndrome Proceedings of the National Academy of Sciences	HE Kong, J Lim, A Linsalata, Y Kang, I Malik, EG Allen, Y Cao, L Shubeck, R Johnston, Y Huang, Y Gu, X Guo, ME Zwick, Z Qin, TS Wingo, J Juncos, DL Nelson, MP Epstein, DJ Cutler, PK Todd, SL Sherman, ST Warren, P Jin	05/26/2022
Across Dimensions: Developing 2D and 3D Human iPSC-Based Models of Fragile X Syndrome Cells	A Lee, J Xu, Z Wen, P Jin	05/24/2022
Epitranscriptomic dynamics in brain development and disease Molecular Psychiatry	AM Shafik, EG Allen, P Jin	04/26/2022
Reducing the Excess Activin Signaling Rescues Muscle Degeneration in Myotonic Dystrophy Type 2 Drosophila Model Journal of Personalized Medicine	J Deng, XX Guan, YB Zhu, HT Deng, GX Li, YC Guo, P Jin, RH Duan, W Huang	03/02/2022
LRcell : detecting the source of differential expression at the sub–cell-type level from bulk RNA-seq data Briefings in Bioinformatics	W Ma, S Sharma, P Jin, SL Gourley, ZS Qin	02/09/2022
Brain microRNAs are associated with variation in cognitive trajectory in advanced age Translational Psychiatry	AP Wingo, M Wang, J Liu, MS Breen, HS Yang, B Tang, JA Schneider, NT Seyfried, JJ Lah, AI Levey, DA Bennett, P Jin, PL De Jager, TS Wingo	02/01/2022
Cell-Free DNA Methylation as a Potential Biomarker in Brain Disorders Epigenomics	Y Jin, EG Allen, P Jin	01/17/2022
Dysregulated mitochondrial and cytosolic tRNA m1A methylation in Alzheimer’s disease Human Molecular Genetics	AM Shafik, H Zhou, J Lim, B Dickinson, P Jin	12/10/2021
Disease category-specific annotation of variants using an ensemble learning framework Briefings in Bioinformatics	Z Cao, Y Huang, R Duan, P Jin, ZS Qin, S Zhang	09/30/2021
Remembering Stephen T. Warren, a pillar of neurogenetics (1953–2021) Nature Neuroscience	P Jin, GJ Bassell	09/13/2021
A human forebrain organoid model of fragile X syndrome exhibits altered neurogenesis and highlights new treatment strategies Nature Neuroscience	Y Kang, Y Zhou, Y Li, Y Han, J Xu, W Niu, Z Li, S Liu, H Feng, W Huang, R Duan, T Xu, N Raj, F Zhang, J Dou, C Xu, H Wu, GJ Bassell, ST Warren, EG Allen, P Jin, Z Wen	08/19/2021
A machine learning approach to brain epigenetic analysis reveals kinases associated with Alzheimer’s disease Nature Communications	Y Huang, X Sun, H Jiang, S Yu, C Robins, MJ Armstrong, R Li, Z Mei, X Shi, ES Gerasimov, PL De Jager, DA Bennett, AP Wingo, P Jin, TS Wingo, ZS Qin	07/22/2021
Stress modulates Ahi1-dependent nuclear localization of ten-eleven translocation protein 2 Human Molecular Genetics	Q Zhang, Q Hu, J Wang, Z Miao, Z Li, Y Zhao, B Wan, EG Allen, M Sun, P Jin, X Xu	06/25/2021
Ten-eleven translocation 2 modulates allergic inflammation by 5-hydroxymethylcytosine remodeling of immunologic pathways Human Molecular Genetics	C Meng, L Gu, Y Li, R Li, Y Cao, Z Li, EG Allen, D Zhu, P Jin	06/18/2021
A Porcine Congenital Single-Sided Deafness Model, Its Population Statistics and Degenerative Changes Frontiers in Cell and Developmental Biology	W Ren, C Xu, FJ Zheng, TT Lin, P Jin, Y Zhang, WW Guo, CH Liu, XY Zhou, LL Wang, Y Wang, H Zhao, SM Yang	06/11/2021
Identifying susceptibility genes for primary ovarian insufficiency on the high-risk genetic background of a fragile X premutation Fertility and Sterility	CE Trevino, JC Rounds, K Charen, L Shubeck, HS Hipp, JB Spencer, HR Johnston, DJ Cutler, ME Zwick, MP Epstein, A Murray, JN Macpherson, M Mila, L Rodriguez-Revenga, E Berry-Kravis, DA Hall, MA Leehey, Y Liu, C Welt, ST Warren, SL Sherman, P Jin, EG Allen	05/18/2021
Therapeutic Development for CGG Repeat Expansion-Associated Neurodegeneration Frontiers in Cellular Neuroscience	K Xu, Y Li, EG Allen, P Jin	05/12/2021
Ten-eleven translocation protein 1 modulates medulloblastoma progression Genome biology	H Kim, Y Kang, Y Li, L Chen, L Lin, ND Johnson, D Zhu, MH Robinson, L McSwain, BG Barwick, X Yuan, X Liao, J Zhao, Z Zhang, Q Shu, J Chen, EG Allen, AM Kenney, RC Castellino, EG Van Meir, KN Conneely, PM Vertino, P Jin, J Li	04/29/2021
Ectopic expression of CGG-repeats alters ovarian response to gonadotropins and leads to infertility in a murine FMR1 premutation model Human Molecular Genetics	KE Shelly, NR Candelaria, Z Li, EG Allen, P Jin, DL Nelson	04/08/2021
Cell-type-specific profiling of human cellular models of fragile X syndrome reveal PI3K-dependent defects in translation and neurogenesis Cell Reports	N Raj, ZT McEachin, W Harousseau, Y Zhou, F Zhang, ME Merritt-Garza, JM Taliaferro, M Kalinowska, SG Marro, CM Hales, E Berry-Kravis, MW Wolf-Ochoa, V Martinez-Cerdeño, M Wernig, L Chen, E Klann, ST Warren, P Jin, Z Wen, GJ Bassell	04/01/2021
Targeting the ALS/FTD-associated A-DNA kink with anthracene-based metal complex causes DNA backbone straightening and groove contraction Nucleic Acids Research	CR Jhan, R Satange, SC Wang, JY Zeng, YC Horng, P Jin, S Neidle, MH Hou	03/26/2021
Downregulation of TOP2 modulates neurodegeneration caused by GGGGCC expanded repeats Human Molecular Genetics	B Jiao, M Wang, H Feng, H Bao, F Zhang, H Wu, J Wang, B Tang, P Jin, L Shen	03/15/2021
Detecting m6A methylation regions from Methylated RNA Immunoprecipitation Sequencing Bioinformatics	Z Guo, AM Shafik, P Jin, Z Wu, H Wu	03/12/2021
Author Correction: An all-to-all approach to the identification of sequence-specific readers for epigenetic DNA modifications on cytosine Nature Communications	G Song, G Wang, X Luo, Y Cheng, Q Song, J Wan, C Moore, H Song, P Jin, J Qian, H Zhu	02/23/2021
An all-to-all approach to the identification of sequence-specific readers for epigenetic DNA modifications on cytosine Nature Communications	G Song, G Wang, X Luo, Y Cheng, Q Song, J Wan, C Moore, H Song, P Jin, J Qian, H Zhu	02/04/2021
N6-methyladenosine dynamics in neurodevelopment and aging, and its potential role in Alzheimer’s disease Genome biology	AM Shafik, F Zhang, Z Guo, Q Dai, K Pajdzik, Y Li, Y Kang, B Yao, H Wu, C He, EG Allen, R Duan, P Jin	01/05/2021
Important Correlates of Purpose in Life Identified Through a Machine Learning Approach American Journal of Geriatric Psychiatry	Z Mei, A Lori, SM Vattathil, PA Boyle, B Bradley, P Jin, DA Bennett, TS Wingo, AP Wingo	09/28/2020
Metabolic Alterations in FMR1 Premutation Carriers Frontiers in Molecular Biosciences	Y Cao, Y Peng, HE Kong, EG Allen, P Jin	09/18/2020
Neuropeptides Modulate Local Astrocytes to Regulate Adult Hippocampal Neural Stem Cells Neuron	B Asrican, J Wooten, YD Li, L Quintanilla, F Zhang, C Wander, H Bao, CY Yeh, YJ Luo, R Olsen, SA Lim, J Hu, P Jin, J Song	09/01/2020
Publisher Correction: Integrated analysis of a compendium of RNA-Seq datasets for splicing factors Scientific Data	P Yu, J Li, SP Deng, F Zhang, PN Grozdanov, EWM Chin, SD Martin, L Vergnes, MS Islam, D Sun, JM LaSalle, SL McGee, E Goh, CC MacDonald, P Jin	08/07/2020
Neddylation activity modulates the neurodegeneration associated with fragile X associated tremor/ataxia syndrome (FXTAS) through regulating Sima Neurobiology of Disease	Y Lin, J Xue, J Deng, H He, S Luo, J Chen, J Li, L Yu, J Zhao, J Chen, EG Allen, P Jin, R Duan	07/09/2020
Integrated analysis of a compendium of RNA-Seq datasets for splicing factors Scientific Data	P Yu, J Li, SP Deng, F Zhang, PN Grozdanov, EWM Chin, SD Martin, L Vergnes, MS Islam, D Sun, JM LaSalle, SL McGee, E Goh, CC MacDonald, P Jin	06/16/2020
Development of Chinese genetic reference panel for Fragile X Syndrome and its application to the screen of 10,000 Chinese pregnant women and women planning pregnancy Molecular Genetics & Genomic Medicine	F Gao, W Huang, Y You, J Huang, J Zhao, J Xue, H Kang, Y Zhu, Z Hu, EG Allen, P Jin, K Xia, R Duan	04/12/2020
Robust partial reference-free cell composition estimation from tissue expression Bioinformatics	Z Li, Z Guo, Y Cheng, P Jin, H Wu	03/10/2020
Dynamic N6-Methyladenosine RNA Methylation in Brain and Diseases Epigenomics	AM Shafik, EG Allen, P Jin	02/01/2020
Proteomic and lipidomic analysis of exosomes derived from ovarian cancer cells and ovarian surface epithelial cells Journal of Ovarian Research	L Cheng, K Zhang, Y Qing, D Li, M Cui, P Jin, T Xu	01/22/2020
Grainyhead-like 2 as a double-edged sword in development and cancer. PubMed	J He, C Feng, H Zhu, S Wu, P Jin, T Xu	01/01/2020
Diverse and dynamic DNA modifications in brain and diseases. Human molecular genetics	MJ Armstrong, Y Jin, EG Allen, P Jin	11/21/2019
Ethnicity-specific and overlapping alterations of brain hydroxymethylome in Alzheimer’s disease Human Molecular Genetics	L Qin, Q Xu, Z Li, L Chen, Y Li, N Yang, Z Liu, J Guo, L Shen, EG Allen, C Chen, C Ma, H Wu, X Zhu, P Jin, B Tang	11/06/2019
Altered 5-Hydroxymethylcytosine Landscape in Primary Gastric Adenocarcinoma DNA and Cell Biology	H Liu, T Xu, Y Cheng, MH Jin, MY Chang, Q Shu, EG Allen, P Jin, X Wang	10/28/2019
Age-related DNA hydroxymethylation is enriched for gene expression and immune system processes in human peripheral blood Epigenetics	ND Johnson, L Huang, R Li, Y Li, Y Yang, HR Kim, C Grant, H Wu, EA Whitsel, DP Kiel, AA Baccarelli, P Jin, JM Murabito, KN Conneely	09/11/2019
Regulatory annotation of genomic intervals based on tissue-specific expression QTLs Bioinformatics	T Xu, P Jin, ZS Qin	08/23/2019
The Taiman Transcriptional Coactivator Engages Toll Signals to Promote Apoptosis and Intertissue Invasion in Drosophila Current Biology	PK Byun, C Zhang, B Yao, J Wardwell-Ozgo, D Terry, P Jin, K Moberg	08/08/2019
Dysfunction of Habituation Learning: A Novel Pathogenic Paradigm of Intellectual Disability and Autism Spectrum Disorder Biological Psychiatry	Y Cheng, P Jin	07/29/2019
Amyotrophic Lateral Sclerosis-associated GGGGCC repeat expansion promotes Tau phosphorylation and toxicity Neurobiology of Disease	H He, W Huang, R Wang, Y Lin, Y Guo, J Deng, H Deng, Y Zhu, EG Allen, P Jin, R Duan	06/06/2019
Expansion of Human-Specific GGC Repeat in Neuronal Intranuclear Inclusion Disease-Related Disorders The American Journal of Human Genetics	Y Tian, JL Wang, W Huang, S Zeng, B Jiao, Z Liu, Z Chen, Y Li, Y Wang, HX Min, XJ Wang, Y You, RX Zhang, XY Chen, F Yi, YF Zhou, HY Long, CJ Zhou, X Hou, JP Wang, B Xie, F Liang, ZY Yang, QY Sun, EG Allen, AM Shafik, HE Kong, JF Guo, XX Yan, ZM Hu, K Xia, H Jiang, HW Xu, RH Duan, P Jin, BS Tang, L Shen	06/06/2019
Rare variants in MYH15 modify amyotrophic lateral sclerosis risk Human Molecular Genetics	H Kim, J Lim, H Bao, B Jiao, SM Canon, MP Epstein, K Xu, J Jiang, J Parameswaran, Y Li, KH Moberg, JE Landers, C Fournier, EG Allen, JD Glass, TS Wingo, P Jin	03/22/2019
Dissecting differential signals in high-throughput data from complex tissues Bioinformatics	Z Li, Z Wu, P Jin, H Wu	03/20/2019
Application of Drosophila Model Toward Understanding the Molecular Basis of Fragile X Syndrome Methods in molecular biology	HE Kong, J Lim, P Jin	01/01/2019
Ten-Eleven Translocation Proteins Modulate the Response to Environmental Stress in Mice Cell Reports	Y Cheng, M Sun, L Chen, Y Li, L Lin, B Yao, Z Li, Z Wang, J Chen, Z Miao, N Xin, L Huang, EG Allen, H Wu, X Xu, P Jin	12/01/2018
Metabolic pathways modulate the neuronal toxicity associated with fragile X-associated tremor/ataxia syndrome Human Molecular Genetics	HE Kong, J Lim, F Zhang, L Huang, Y Gu, DL Nelson, EG Allen, P Jin	11/23/2018
Partial loss of psychiatric risk gene Mir137 in mice causes repetitive behavior and impairs sociability and learning via increased Pde10a Nature Neuroscience	Y Cheng, ZM Wang, W Tan, X Wang, Y Li, B Bai, Y Li, SF Zhang, HL Yan, ZL Chen, CM Liu, TW Mi, S Xia, Z Zhou, A Liu, GB Tang, C Liu, ZJ Dai, YY Wang, H Wang, X Wang, Y Kang, L Lin, Z Chen, N Xie, Q Sun, W Xie, J Peng, D Chen, ZQ Teng, P Jin	10/31/2018
A comprehensive review of computational prediction of genome-wide features Briefings in Bioinformatics	T Xu, X Zheng, B Li, P Jin, Z Qin, H Wu	10/18/2018
Reversing Behavioral, Neuroanatomical, and Germline Influences of Intergenerational Stress Biological Psychiatry	HS Aoued, S Sannigrahi, N Doshi, FG Morrison, H Linsenbaum, SC Hunter, H Walum, J Baman, B Yao, P Jin, KJ Ressler, BG Dias	08/27/2018
Fragile X mental retardation protein modulates the stability of its m6A-marked messenger RNA targets Human Molecular Genetics	F Zhang, Y Kang, M Wang, Y Li, T Xu, W Yang, H Song, H Wu, Q Shu, P Jin	08/08/2018
Active N6-Methyladenine Demethylation by DMAD Regulates Gene Expression by Coordinating with Polycomb Protein in Neurons Molecular Cell	B Yao, Y Li, Z Wang, L Chen, M Poidevin, C Zhang, L Lin, F Wang, H Bao, B Jiao, J Lim, Y Cheng, L Huang, BL Phillips, T Xu, R Duan, KH Moberg, H Wu, P Jin	08/02/2018
5-Hydroxymethylcytosine alterations in the human postmortem brains of autism spectrum disorder Human Molecular Genetics	Y Cheng, Z Li, S Manupipatpong, L Lin, X Li, T Xu, YH Jiang, Q Shu, H Wu, P Jin	05/16/2018
Optimized distributed systems achieve significant performance improvement on sorted merging of massive VCF files GigaScience	X Sun, J Gao, P Jin, C Eng, EG Burchard, TH Beaty, I Ruczinski, RA Mathias, K Barnes, F Wang, ZS Qin	05/10/2018
A unique epigenomic landscape defines the characteristics and differentiation potentials of glioma stem cells Genome biology	B Yao, P Jin	04/10/2018
Disease prediction by cell-free DNA methylation Briefings in Bioinformatics	H Feng, P Jin, H Wu	03/25/2018
Developing DNA methylation-based diagnostic biomarkers Journal of genetics and genomics/Journal of Genetics and Genomics	H Kim, X Wang, P Jin	02/01/2018
Medical genetics: Towards precision medicine Journal of genetics and genomics/Journal of Genetics and Genomics	P Jin	02/01/2018
Piperine ameliorates SCA17 neuropathology by reducing ER stress Molecular Neurodegeneration	J Guo, Y Cui, Q Liu, Y Yang, Y Li, L Weng, B Tang, P Jin, XJ Li, S Yang, S Li	01/30/2018
Epitranscriptomic m6A Regulation of Axon Regeneration in the Adult Mammalian Nervous System Neuron	YL Weng, X Wang, R An, J Cassin, C Vissers, Y Liu, Y Liu, T Xu, X Wang, SZH Wong, J Joseph, LC Dore, Q Dong, W Zheng, P Jin, H Wu, B Shen, X Zhuang, C He, K Liu, H Song, GL Ming	01/01/2018
DNA N6-methyladenine is dynamically regulated in the mouse brain following environmental stress Nature Communications	B Yao, Y Cheng, Z Wang, Y Li, L Chen, L Huang, W Zhang, D Chen, H Wu, B Tang, P Jin	10/18/2017
Temporal Control of Mammalian Cortical Neurogenesis by m6A Methylation Cell	KJ Yoon, FR Ringeling, C Vissers, F Jacob, M Pokrass, D Jimenez-Cyrus, Y Su, NS Kim, Y Zhu, L Zheng, S Kim, X Wang, LC Doré, P Jin, S Regot, X Zhuang, S Canzar, C He, GL Ming, H Song	09/29/2017
Zika-Virus-Encoded NS2A Disrupts Mammalian Cortical Neurogenesis by Degrading Adherens Junction Proteins Cell stem cell	KJ Yoon, G Song, X Qian, J Pan, D Xu, HS Rho, NS Kim, C Habela, L Zheng, F Jacob, F Zhang, EM Lee, WK Huang, FR Ringeling, C Vissers, C Li, L Yuan, K Kang, S Kim, J Yeo, Y Cheng, S Liu, Z Wen, CF Qin, Q Wu, KM Christian, H Tang, P Jin, Z Xu, J Qian, H Zhu, H Song, GL Ming	08/17/2017
Zika virus directly infects peripheral neurons and induces cell death Nature Neuroscience	Y Oh, F Zhang, Y Wang, EM Lee, IY Choi, H Lim, F Mirakhori, R Li, L Huang, T Xu, H Wu, C Li, CF Qin, Z Wen, QF Wu, H Tang, Z Xu, P Jin, H Song, GL Ming, G Lee	07/31/2017
Ten-eleven translocation 2 interacts with forkhead box O3 and regulates adult neurogenesis Nature Communications	X Li, B Yao, L Chen, Y Kang, Y Li, Y Cheng, L Li, L Lin, Z Wang, M Wang, F Pan, Q Dai, W Zhang, H Wu, Q Shu, Z Qin, C He, M Xu, P Jin	06/29/2017
CRISPR/Cas9-mediated gene editing ameliorates neurotoxicity in mouse model of Huntington’s disease Journal of Clinical Investigation	S Yang, R Chang, H Yang, T Zhao, Y Hong, HE Kong, X Sun, Z Qin, P Jin, S Li, XJ Li	06/18/2017
Fragile X-Associated Tremor/Ataxia Syndrome: From Molecular Pathogenesis to Development of Therapeutics Frontiers in Cellular Neuroscience	HE Kong, J Zhao, S Xu, P Jin, Y Jin	05/05/2017
Tet2 loss leads to hypermutagenicity in haematopoietic stem/progenitor cells Nature Communications	F Pan, TS Wingo, Z Zhao, R Gao, H Makishima, G Qu, L Lin, M Yu, JR Ortega, J Wang, A Nazha, L Chen, B Yao, C Liu, S Chen, O Weeks, H Ni, BL Phillips, S Huang, J Wang, C He, GM Li, T Radivoyevitch, I Aifantis, JP Maciejewski, FC Yang, P Jin, M Xu	04/25/2017
Fat mass and obesity-associated (FTO) protein regulates adult neurogenesis Human Molecular Genetics	L Li, L Zang, F Zhang, J Chen, H Shen, L Shu, F Liang, C Feng, D Chen, H Tao, T Xu, Z Li, Y Kang, H Wu, L Tang, P Zhang, P Jin, Q Shu, X Li	03/29/2017
A genome‐wide profiling of brain DNA hydroxymethylation in Alzheimer's disease Alzheimer s & Dementia	J Zhao, Y Zhu, J Yang, L Li, H Wu, PL De Jager, P Jin, DA Bennett	01/06/2017
DIVAN: accurate identification of non-coding disease-specific risk variants using multi-omics profiles Genome biology	L Chen, P Jin, ZS Qin	12/01/2016
WITHDRAWN: Global and site-specific changes in 5-methylcytosine and 5-hydroxymethylcytosine after extended post-mortem interval Experimental and Molecular Pathology	JA Gross, C Nagy, L Lin, É Bonneil, M Maheu, P Thibault, N Mechawar, P Jin, G Turecki	10/01/2016
Structural dynamics control the MicroRNA maturation pathway Nucleic Acids Research	P Dallaire, H Tan, K Szulwach, C Ma, P Jin, F Major	09/19/2016
Genome-wide association study of positive emotion identifies a genetic variant and a role for microRNAs Molecular Psychiatry	AP Wingo, LM Almli, JS Stevens, T Jovanovic, TS Wingo, G Tharp, Y Li, A Lori, M Briscione, P Jin, EB Binder, B Bradley, G Gibson, KJ Ressler	09/06/2016
Distinctive Klf4 mutants determine preference for DNA methylation status Nucleic Acids Research	H Hashimoto, D Wang, AN Steves, P Jin, RM Blumenthal, X Zhang, X Cheng	09/04/2016
Sex-specific hippocampal 5-hydroxymethylcytosine is disrupted in response to acute stress Neurobiology of Disease	LA Papale, S Li, A Madrid, Q Zhang, L Chen, P Chopra, P Jin, S Keleş, RS Alisch	09/02/2016
Molecular signatures associated with ZIKV exposure in human cortical neural progenitors Nucleic Acids Research	F Zhang, C Hammack, SC Ogden, Y Cheng, EM Lee, Z Wen, X Qian, HN Nguyen, Y Li, B Yao, M Xu, T Xu, L Chen, Z Wang, H Feng, WK Huang, KJ Yoon, C Shan, L Huang, Z Qin, KM Christian, PY Shi, M Xu, M Xia, W Zheng, H Wu, H Song, H Tang, GL Ming, P Jin	08/31/2016
Histone deacetylase 3 associates with MeCP2 to regulate FOXO and social behavior Nature Neuroscience	A Nott, J Cheng, F Gao, YT Lin, E Gjoneska, T Ko, P Minhas, AV Zamudio, J Meng, F Zhang, P Jin, LH Tsai	07/18/2016
Global and Site-Specific Changes in 5-Methylcytosine and 5-Hydroxymethylcytosine after Extended Post-mortem Interval Frontiers in Genetics	JA Gross, C Nagy, L Lin, É Bonneil, M Maheu, P Thibault, N Mechawar, P Jin, G Turecki	06/23/2016
Epigenetic mechanisms in neurogenesis Nature reviews. Neuroscience	B Yao, KM Christian, C He, P Jin, GL Ming, H Song	06/23/2016
Genome-wide alteration of 5-hydroxymenthylcytosine in a mouse model of Alzheimer’s disease BMC Genomics	L Shu, W Sun, L Li, Z Xu, L Lin, P Xie, H Shen, L Huang, Q Xu, P Jin, X Li	05/20/2016
Brain-Region-Specific Organoids Using Mini-bioreactors for Modeling ZIKV Exposure Cell	X Qian, HN Nguyen, MM Song, C Hadiono, SC Ogden, C Hammack, B Yao, GR Hamersky, F Jacob, C Zhong, KJ Yoon, W Jeang, L Lin, Y Li, J Thakor, DA Berg, C Zhang, E Kang, M Chickering, D Nauen, CY Ho, Z Wen, KM Christian, PY Shi, BJ Maher, H Wu, P Jin, H Tang, H Song, GL Ming	04/30/2016
5-Hydroxymethylation-associated epigenetic modifiers of Alzheimer’s disease modulate Tau-induced neurotoxicity Human Molecular Genetics	AI Bernstein, Y Lin, RC Street, L Lin, Q Dai, L Yu, H Bao, M Gearing, JJ Lah, PT Nelson, C He, AI Levey, JG Mullé, R Duan, P Jin	04/09/2016
5-Hydroxymethylcytosine-mediated alteration of transposon activity associated with the exposure to adversein uteroenvironments in human Human Molecular Genetics	M Sun, MM Song, B Wei, Q Gao, L Li, B Yao, L Chen, L Lin, Q Dai, X Zhou, J Tao, J Chen, C He, P Jin, Z Xu	03/22/2016
Zika Virus Infects Human Cortical Neural Progenitors and Attenuates Their Growth Cell stem cell	H Tang, C Hammack, SC Ogden, Z Wen, X Qian, Y Li, B Yao, J Shin, F Zhang, EM Lee, KM Christian, RA Didier, P Jin, H Song, GL Ming	03/05/2016
DNA Methylation Dynamics in Neurogenesis Epigenomics	Z Wang, B Tang, Y He, P Jin	03/01/2016
The Drosophila Helicase MLE Targets Hairpin Structures in Genomic Transcripts PLoS Genetics	S Cugusi, Y Li, P Jin, JC Lucchesi	01/11/2016
Structural basis of nucleic-acid recognition and double-strand unwinding by the essential neuronal protein Pur-alpha eLife	J Weber, H Bao, C Hartlmüller, Z Wang, A Windhager, R Janowski, T Madl, P Jin, D Niessing	01/08/2016
Lin28A Binds Active Promoters and Recruits Tet1 to Regulate Gene Expression Molecular Cell	Y Zeng, B Yao, J Shin, L Lin, N Kim, Q Song, S Liu, Y Su, JU Guo, L Huang, J Wan, H Wu, J Qian, X Cheng, H Zhu, GL Ming, P Jin, H Song	12/18/2015
DICER1 and microRNA regulation in post-traumatic stress disorder with comorbid depression Nature Communications	AP Wingo, LM Almli, JS Stevens, T Klengel, M Uddin, Y Li, AC Bustamante, A Lori, N Koen, DJ Stein, AK Smith, AE Aiello, KC Koenen, DE Wildman, S Galea, B Bradley, EB Binder, P Jin, G Gibson, KJ Ressler	12/03/2015
Genome-wide alterations in hippocampal 5-hydroxymethylcytosine links plasticity genes to acute stress Neurobiology of Disease	S Li, LA Papale, Q Zhang, A Madrid, L Chen, P Chopra, S Keleş, P Jin, RS Alisch	11/18/2015
Combined Loss of Tet1 and Tet2 Promotes B Cell, but Not Myeloid Malignancies, in Mice Cell Reports	Z Zhao, L Chen, MM Dawlaty, F Pan, O Weeks, Y Zhou, Z Cao, H Shi, J Wang, L Lin, S Chen, W Yuan, Z Qin, H Ni, SD Nimer, FC Yang, R Jaenisch, P Jin, M Xu	11/01/2015
Small Molecules Efficiently Reprogram Human Astroglial Cells into Functional Neurons Cell stem cell	L Zhang, JC Yin, H Yeh, NX Ma, G Lee, XA Chen, Y Wang, L Lin, L Chen, P Jin, GY Wu, G Chen	10/23/2015
Altering 5-hydroxymethylcytosine modification impacts ischemic brain injury Human Molecular Genetics	Z Miao, Y He, N Xin, M Sun, L Chen, L Lin, J Li, J Kong, P Jin, X Xu	07/30/2015
Detection of differentially methylated regions from whole-genome bisulfite sequencing data without replicates Nucleic Acids Research	H Wu, T Xu, H Feng, L Chen, B Li, B Yao, Z Qin, P Jin, KN Conneely	07/15/2015
The Ecdysone Receptor Coactivator Taiman Links Yorkie to Transcriptional Control of Germline Stem Cell Factors in Somatic Tissue Developmental Cell	C Zhang, BS Robinson, W Xu, L Yang, B Yao, H Zhao, PK Byun, P Jin, A Veraksa, KH Moberg	07/01/2015
Promoters of Human Cosmc and T-synthase Genes Are Similar in Structure, Yet Different in Epigenetic Regulation Journal of Biological Chemistry	J Zeng, R Mi, Y Wang, Y Li, L Lin, B Yao, L Song, I van Die, AB Chapman, RD Cummings, P Jin, T Ju	06/11/2015
Gossypol Acetic Acid Prevents Oxidative Stress-Induced Retinal Pigment Epithelial Necrosis by Regulating the FoxO3/Sestrin2 Pathway Molecular and Cellular Biology	J Hanus, H Zhang, DH Chen, Q Zhou, P Jin, Q Liu, S Wang	03/24/2015
Role of Tet1 and 5-hydroxymethylcytosine in cocaine action Nature Neuroscience	J Feng, N Shao, KE Szulwach, V Vialou, J Huynh, C Zhong, T Le, D Ferguson, ME Cahill, Y Li, JW Koo, E Ribeiro, B Labonte, BM Laitman, D Estey, V Stockman, P Kennedy, T Couroussé, I Mensah, G Turecki, KF Faull, GL Ming, H Song, G Fan, P Casaccia, L Shen, P Jin, EJ Nestler	03/16/2015
Base-resolution methylation patterns accurately predict transcription factor bindings in vivo Nucleic Acids Research	T Xu, B Li, M Zhao, KE Szulwach, RC Street, L Lin, B Yao, F Zhang, P Jin, H Wu, ZS Qin	02/26/2015
Glutamate Dehydrogenase 1 Signals through Antioxidant Glutathione Peroxidase 1 to Regulate Redox Homeostasis and Tumor Growth Cancer Cell	L Jin, D Li, GN Alesi, J Fan, HB Kang, Z Lu, TJ Boggon, P Jin, H Yi, ER Wright, D Duong, NT Seyfried, R Egnatchik, RJ DeBerardinis, KR Magliocca, C He, ML Arellano, HJ Khoury, DM Shin, FR Khuri, S Kang	02/01/2015
Independent role for presynaptic FMRP revealed by an FMR1 missense mutation associated with intellectual disability and seizures Proceedings of the National Academy of Sciences	LK Myrick, PY Deng, H Hashimoto, YM Oh, Y Cho, MJ Poidevin, JA Suhl, J Visootsak, V Cavalli, P Jin, X Cheng, ST Warren, VA Klyachko	01/05/2015
Small-Molecule Screening Using Drosophila Models of Human Neurological Disorders Methods in molecular biology	M Poidevin, F Zhang, P Jin	12/20/2014
Environmental enrichment modulates 5-hydroxymethylcytosine dynamics in hippocampus Genomics	H Irier, RC Street, R Dave, L Lin, C Cai, TH Davis, B Yao, Y Cheng, P Jin	09/07/2014
Towards Understanding RNA-Mediated Neurological Disorders Journal of genetics and genomics/Journal of Genetics and Genomics	R Duan, S Sharma, Q Xia, K Garber, P Jin	08/23/2014
Use of model systems to understand the etiology of fragile X-associated primary ovarian insufficiency (FXPOI) Journal of Neurodevelopmental Disorders	SL Sherman, EC Curnow, CA Easley, P Jin, RK Hukema, MI Tejada, R Willemsen, K Usdin	08/13/2014
AGO3 Slicer activity regulates mitochondria–nuage localization of Armitage and piRNA amplification The Journal of Cell Biology	H Huang, Y Li, KE Szulwach, G Zhang, P Jin, D Chen	07/21/2014
CGG repeats in RNA modulate expression of TDP-43 in mouse and fly models of fragile X tremor ataxia syndrome Human Molecular Genetics	JN Galloway, C Shaw, P Yu, D Parghi, M Poidevin, P Jin, DL Nelson	06/30/2014
Unlocking epigenetic codes in neurogenesis Genes & Development	B Yao, P Jin	06/15/2014
Fat mass and obesity-associated (FTO) protein interacts with CaMKII and modulates the activity of CREB signaling pathway. Human molecular genetics	L Lin, CM Hales, K Garber, P Jin	06/15/2014
5-Hydroxymethylcytosine: A new player in brain disorders? Experimental Neurology	Y Cheng, A Bernstein, D Chen, P Jin	05/17/2014
A feed-forward mechanism involving Drosophila fragile X mental retardation protein triggers a replication stress-induced DNA damage response Human Molecular Genetics	W Zhang, Y Cheng, Y Li, Z Chen, P Jin, D Chen	05/15/2014
Coordination of Engineered Factors with TET1/2 Promotes Early-Stage Epigenetic Modification during Somatic Cell Reprogramming Stem Cell Reports	G Zhu, Y Li, F Zhu, T Wang, W Jin, W Mu, W Lin, W Tan, W Li, RC Street, S Peng, J Zhang, Y Feng, ST Warren, Q Sun, P Jin, D Chen	02/27/2014
Genome-wide antagonism between 5-hydroxymethylcytosine and DNA methylation in the adult mouse brain Frontiers in Biology	JU Guo, KE Szulwach, Y Su, Y Li, B Yao, Z Xu, JH Shin, B Xie, Y Gao, GL Ming, P Jin, H Song	02/01/2014
Cell-Cycle Control of Developmentally Regulated Transcription Factors Accounts for Heterogeneity in Human Pluripotent Cells Stem Cell Reports	AM Singh, J Chappell, R Trost, L Lin, T Wang, J Tang, BK Matlock, KP Weller, H Wu, S Zhao, P Jin, S Dalton	12/01/2013
Integrating DNA methylation dynamics into a framework for understanding epigenetic codes BioEssays	KE Szulwach, P Jin	11/18/2013
Genome-wide alteration of 5-hydroxymethylcytosine in a mouse model of fragile X-associated tremor/ataxia syndrome Human Molecular Genetics	B Yao, L Lin, RC Street, ZA Zalewski, JN Galloway, H Wu, DL Nelson, P Jin	10/09/2013
Toward pluripotency by reprogramming: mechanisms and application Protein & Cell	T Wang, ST Warren, P Jin	09/28/2013
U1 small nuclear ribonucleoprotein complex and RNA splicing alterations in Alzheimer’s disease Proceedings of the National Academy of Sciences	B Bai, CM Hales, PC Chen, Y Gozal, EB Dammer, JJ Fritz, X Wang, Q Xia, DM Duong, C Street, G Cantero, D Cheng, DR Jones, Z Wu, Y Li, I Diner, CJ Heilman, HD Rees, H Wu, L Lin, KE Szulwach, M Gearing, EJ Mufson, DA Bennett, TJ Montine, NT Seyfried, TS Wingo, YE Sun, P Jin, J Hanfelt, DM Willcock, A Levey, JJ Lah, J Peng	09/10/2013
Cytosine modifications in neurodevelopment and diseases Cellular and Molecular Life Sciences	B Yao, P Jin	08/02/2013
TET1 plays an essential oncogenic role in MLL -rearranged leukemia Proceedings of the National Academy of Sciences	H Huang, X Jiang, Z Li, Y Li, CX Song, C He, M Sun, P Chen, S Gurbuxani, J Wang, GM Hong, AG Elkahloun, S Arnovitz, J Wang, K Szulwach, L Lin, C Street, M Wunderlich, M Dawlaty, MB Neilly, R Jaenisch, FC Yang, JC Mulloy, P Jin, PP Liu, JD Rowley, M Xu, C He, J Chen	07/01/2013
Probing the microRNA pathway with small molecules Bioorganic & Medicinal Chemistry	Y Li, P Ji, P Jin	05/24/2013
Subtelomeric hotspots of aberrant 5-hydroxymethylcytosine-mediated epigenetic modifications during reprogramming to pluripotency Nature Cell Biology	T Wang, H Wu, Y Li, KE Szulwach, L Lin, X Li, IP Chen, IS Goldlust, SJ Chamberlain, A Dodd, H Gong, G Ananiev, JW Han, YS Yoon, MK Rudd, M Yu, CX Song, C He, Q Chang, ST Warren, P Jin	05/19/2013
Expanded GGGGCC repeat RNA associated with amyotrophic lateral sclerosis and frontotemporal dementia causes neurodegeneration. Proceedings of the National Academy of Sciences of the United States of America	Z Xu, M Poidevin, X Li, Y Li, L Shu, DL Nelson, H Li, CM Hales, M Gearing, TS Wingo, P Jin	05/07/2013
Tyr26 phosphorylation of PGAM1 provides a metabolic advantage to tumours by stabilizing the active conformation Nature Communications	T Hitosugi, L Zhou, J Fan, S Elf, L Zhang, J Xie, Y Wang, TL Gu, M Alečković, G LeRoy, Y Kang, HB Kang, JH Seo, C Shan, P Jin, W Gong, S Lonial, ML Arellano, HJ Khoury, GZ Chen, DM Shin, FR Khuri, TJ Boggon, S Kang, C He, J Chen	04/30/2013
Genome-wide Profiling of 5-Formylcytosine Reveals Its Roles in Epigenetic Priming Cell	CX Song, KE Szulwach, Q Dai, Y Fu, SQ Mao, L Lin, C Street, Y Li, M Poidevin, H Wu, J Gao, P Liu, L Li, GL Xu, P Jin, C He	04/01/2013
Tet-mediated covalent labelling of 5-methylcytosine for its genome-wide detection and sequencing Nature Communications	L Zhang, KE Szulwach, GC Hon, CX Song, B Park, M Yu, X Lu, Q Dai, X Wang, CR Street, H Tan, JH Min, B Ren, P Jin, C He	02/26/2013
SRPK2 Phosphorylates Tau and Mediates the Cognitive Defects in Alzheimer's Disease Journal of Neuroscience	Y Hong, CB Chan, IS Kwon, X Li, M Song, HP Lee, X Liu, P Sompol, P Jin, HG Lee, SP Yu, K Ye	11/28/2012
Phosphoglycerate Mutase 1 Coordinates Glycolysis and Biosynthesis to Promote Tumor Growth Cancer Cell	T Hitosugi, L Zhou, S Elf, J Fan, HB Kang, JH Seo, C Shan, Q Dai, L Zhang, J Xie, TL Gu, P Jin, M Alečković, G LeRoy, Y Kang, JA Sudderth, RJ DeBerardinis, CH Luan, GZ Chen, S Muller, DM Shin, TK Owonikoko, S Lonial, ML Arellano, HJ Khoury, FR Khuri, BH Lee, K Ye, TJ Boggon, S Kang, C He, J Chen	11/01/2012
Genome-wide DNA hydroxymethylation changes are associated with neurodevelopmental genes in the developing human cerebellum Human Molecular Genetics	T Wang, Q Pan, L Lin, KE Szulwach, CX Song, C He, H Wu, ST Warren, P Jin, R Duan, X Li	10/05/2012
Selective Capture of 5-hydroxymethylcytosine from Genomic DNA Journal of Visualized Experiments	Y Li, CX Song, C He, P Jin	10/05/2012
Epigenetics-Based Therapeutics for Neurodegenerative Disorders Current Geriatrics Reports	Z Xu, H Li, P Jin	09/17/2012
Stable isotope labeling with amino acids in Drosophila for quantifying proteins and modifications. Journal of proteome research	P Xu, H Tan, DM Duong, Y Yang, J Kupsco, KH Moberg, H Li, P Jin, J Peng	09/07/2012
5-Hydroxymethylcytosine (5-hmC) Specific Enrichment. Bio-protocol	KE Szulwach, CX Song, C He, P Jin	08/05/2012
Iron Homeostasis Regulates the Activity of the MicroRNA Pathway through Poly(C)-Binding Protein 2 Cell Metabolism	Y Li, L Lin, Z Li, X Ye, K Xiong, B Aryal, Z Xu, Z Paroo, Q Liu, C He, P Jin	05/24/2012
MicroRNA-277 Modulates the Neurodegeneration Caused by Fragile X Premutation rCGG Repeats PLoS Genetics	H Tan, M Poidevin, H Li, D Chen, P Jin	05/03/2012
RNA-mediated neurodegeneration in fragile X-associated tremor/ataxia syndrome Brain Research	Y Li, P Jin	03/09/2012
Dynamics of DNA Methylation in Aging and Alzheimer's Disease DNA and Cell Biology	HA Irier, P Jin	02/07/2012
Chemical screen reveals small molecules suppressing fragile X premutation rCGG repeat-mediated neurodegeneration in Drosophila Human Molecular Genetics	A Qurashi, H Liu, L Ray, DL Nelson, R Duan, P Jin	02/01/2012
Role of noncoding RNAs in trinucleotide repeat neurodegenerative disorders Experimental Neurology	H Tan, Z Xu, P Jin	01/30/2012
5-hmC–mediated epigenetic dynamics during postnatal neurodevelopment and aging Nature Neuroscience	KE Szulwach, X Li, Y Li, CX Song, H Wu, Q Dai, H Irier, AK Upadhyay, M Gearing, AI Levey, A Vasanthakumar, LA Godley, Q Chang, X Cheng, C He, P Jin	10/30/2011
Retrotransposon activation contributes to fragile X premutation rCGG-mediated neurodegeneration Human Molecular Genetics	H Tan, A Qurashi, M Poidevin, DL Nelson, H Li, P Jin	09/22/2011
Fragile X Mental Retardation Protein and Stem Cells Results and problems in cell differentiation	A Qurashi, X Li, P Jin	09/21/2011
Integrating 5-Hydroxymethylcytosine into the Epigenomic Landscape of Human Embryonic Stem Cells PLoS Genetics	KE Szulwach, X Li, Y Li, CX Song, JW Han, S Kim, S Namburi, K Hermetz, JJ Kim, MK Rudd, YS Yoon, B Ren, C He, P Jin	06/23/2011
Nuclear Accumulation of Stress Response mRNAs Contributes to the Neurodegeneration Caused by Fragile X Premutation rCGG Repeats PLoS Genetics	A Qurashi, W Li, JY Zhou, J Peng, P Jin	06/02/2011
RNA-Binding Protein FXR2 Regulates Adult Hippocampal Neurogenesis by Reducing Noggin Expression Neuron	W Guo, L Zhang, DM Christopher, ZQ Teng, SR Fausett, C Liu, OL George, J Klingensmith, P Jin, X Zhao	06/01/2011
Selective chemical labeling reveals the genome-wide distribution of 5-hydroxymethylcytosine Nature Biotechnology	CX Song, KE Szulwach, Y Fu, Q Dai, C Yi, X Li, Y Li, CH Chen, W Zhang, X Jian, J Wang, L Zhang, TJ Looney, B Zhang, LA Godley, LM Hicks, BT Lahn, P Jin, C He	12/12/2010
Emergence of Chemical Biology Approaches to the RNAi/miRNA Pathway Chemistry & Biology	Y Li, C He, P Jin	06/01/2010
MicroRNA miR-137 Regulates Neuronal Maturation by Targeting Ubiquitin Ligase Mind Bomb-1 Stem Cells	RD Smrt, KE Szulwach, RL Pfeiffer, X Li, W Guo, M Pathania, ZQ Teng, Y Luo, J Peng, A Bordey, P Jin, X Zhao	04/21/2010
Cross talk between microRNA and epigenetic regulation in adult neurogenesis The Journal of Cell Biology	KE Szulwach, X Li, RD Smrt, Y Li, Y Luo, L Lin, NJ Santistevan, W Li, X Zhao, P Jin	04/05/2010
Roles of small regulatory RNAs in determining neuronal identity Nature reviews. Neuroscience	X Li, P Jin	03/31/2010
Small RNA-Mediated Gene Regulation in Neurodevelopmental Disorders Current Psychiatry Reports	A Qurashi, P Jin	03/18/2010
Macro Role(s) of MicroRNAs in Fragile X Syndrome? NeuroMolecular Medicine	X Li, P Jin	08/10/2009
RNA-mediated pathogenesis in fragile X-associated disorders Neuroscience Letters	H Tan, H Li, P Jin	07/24/2009
Germline mutation of microRNA-125a is associated with breast cancer Journal of Medical Genetics	W Li, R Duan, F Kooy, SL Sherman, W Zhou, P Jin	05/01/2009
Small regulatory RNAs in neurodevelopmental disorders Human Molecular Genetics	S Chang, S Wen, D Chen, P Jin	03/18/2009
Noncoding RNAs in mental retardation Clinical Genetics	KE Szulwach, P Jin, RS Alisch	01/21/2009
A small molecule enhances RNA interference and promotes microRNA processing Nature Biotechnology	G Shan, Y Li, J Zhang, W Li, KE Szulwach, R Duan, MA Faghihi, AM Khalil, L Lu, Z Paroo, AW Chan, Z Shi, Q Liu, C Wahlestedt, C He, P Jin	07/20/2008
The microRNA pathway and fragile X mental retardation protein Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms	Y Li, L Lin, P Jin	07/19/2008
Identification of small molecules rescuing fragile X syndrome phenotypes in Drosophila Nature Chemical Biology	S Chang, SM Bray, Z Li, DC Zarnescu, C He, P Jin, ST Warren	03/09/2008
FXTAS: a bad RNA and a hope for a cure Expert Opinion on Biological Therapy	G Shan, S Xu, P Jin	02/25/2008
Pur α Binds to rCGG Repeats and Modulates Repeat-Mediated Neurodegeneration in a Drosophila Model of Fragile X Tremor/Ataxia Syndrome Neuron	P Jin, R Duan, A Qurashi, Y Qin, D Tian, TC Rosser, H Liu, Y Feng, ST Warren	08/01/2007