Peng Jin, PhD
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Research Program
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Phone Number
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Email Address
Biography
Education
Dr. Peng Jin received his doctorate degree in Molecular and Developmental Biology from Cincinnati Children’s Hospital/University of Cincinnati and completed postdoctoral training at Emory University.
Titles & Roles
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Professor and Chair, Department of Human GeneticsEmory University School of Medicine
Research
Dr. Jin's research philosophy combines various disciplines (biochemistry, genetics, chemistry, human genetics/genomics, and bioinformatics) to understand the functions and mechanisms of epigenetics and noncoding RNAs in neurodevelopmental and neurodegenerative disorders.
Grants
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Publications
Dr. Jin is the recipient of Beckman Young Investigator Award, Basil O'Connor Scholar Research Award, Alfred P. Sloan Research Fellow in Neuroscience, and NARSAD Independent Investigator Award.
Title/Journal Authors Publication Date Transcription Factor-Wide Association Studies to Identify Functional SNPs in Alzheimer's Disease.
The Journal of neuroscience : the official journal of the Society for Neuroscience
J Dunn, C Moore, NS Kim, T Gao, Z Cheng, P Jin, GL Ming, J Qian, Y Su, H Song, H Zhu 01/08/2025 bioRxiv : the preprint server for biology
X Lu, V Keo, I Cheng, W Xie, G Gritsina, J Wang, Q Jin, P Jin, F Yue, MG Sanda, V Corces, N Altemose, JC Zhao, J Yu 12/07/2024 Characterization and visualization of tandem repeats at genome scale.
Nature biotechnology
E Dolzhenko, A English, H Dashnow, G De Sena Brandine, T Mokveld, WJ Rowell, C Karniski, Z Kronenberg, MC Danzi, WA Cheung, C Bi, E Farrow, A Wenger, KP Chua, V Martínez-Cerdeño, TD Bartley, P Jin, DL Nelson, S Zuchner, T Pastinen, AR Quinlan, FJ Sedlazeck, MA Eberle 10/01/2024 Cell-type-specific mapping of enhancers and target genes from single-cell multimodal data.
bioRxiv : the preprint server for biology
C Su, D Lee, P Jin, J Zhang 09/26/2024 Bioinformatics (Oxford, England)
X Ma, SR Thela, F Zhao, B Yao, Z Wen, P Jin, J Zhao, L Chen 09/02/2024 Decoding the role of DNA methylation in allergic diseases: from pathogenesis to therapy.
Cell & bioscience
R Han, D Zhu, J Sha, B Zhao, P Jin, C Meng 07/04/2024 bioRxiv : the preprint server for biology
HV Wang, JF Xiang, C Yuan, AM Veire, TF Gendron, ME Murray, MG Tansey, J Hu, M Gearing, JD Glass, P Jin, VG Corces, ZT McEachin 06/13/2024 Molecular neurobiology
Z Mei, J Liu, JP Schroeder, D Weinshenker, DM Duong, NT Seyfried, Y Li, P Jin, AP Wingo, TS Wingo 06/01/2024 Bridging the gap: R-loop mediated genomic instability and its implications in neurological diseases.
Epigenomics
KR Westover, P Jin, B Yao 03/26/2024 bioRxiv : the preprint server for biology
X Ma, SR Thela, F Zhao, B Yao, Z Wen, P Jin, J Zhao, L Chen 03/06/2024 Epigenetic modifications of DNA and RNA in Alzheimer's disease.
Frontiers in molecular neuroscience
P Martinez-Feduchi, P Jin, B Yao 01/01/2024 BMC medicine
J Ye, Z Huang, Q Li, Z Li, Y Lan, Z Wang, C Ni, X Wu, T Jiang, Y Li, Q Yang, J Lim, CY Ren, M Jiang, S Li, P Jin, JH Chen, C Zhao 12/12/2023 FMRP phosphorylation modulates neuronal translation through YTHDF1.
Molecular cell
Z Zou, J Wei, Y Chen, Y Kang, H Shi, F Yang, Z Shi, S Chen, Y Zhou, C Sepich-Poore, X Zhuang, X Zhou, H Jiang, Z Wen, P Jin, C Luo, C He 12/07/2023 Cells
F Tassone, D Protic, EG Allen, AD Archibald, A Baud, TW Brown, DB Budimirovic, J Cohen, B Dufour, R Eiges, N Elvassore, LV Gabis, SJ Grudzien, DA Hall, D Hessl, A Hogan, JE Hunter, P Jin, P Jiraanont, J Klusek, RF Kooy, CM Kraan, C Laterza, A Lee, K Lipworth, M Losh, D Loesch, R Lozano, MR Mailick, A Manolopoulos, V Martinez-Cerdeno, Y McLennan, RM Miller, FAM Montanaro, MW Mosconi, SN Potter, M Raspa, SM Rivera, K Shelly, PK Todd, K Tutak, JY Wang, A Wheeler, TI Winarni, M Zafarullah, RJ Hagerman 09/21/2023 Role of TET1-mediated epigenetic modulation in Alzheimer's disease.
Neurobiology of disease
MJ Armstrong, Y Jin, SM Vattathil, Y Huang, JP Schroeder, DA Bennet, ZS Qin, TS Wingo, P Jin 09/01/2023 Research square
Z Mei, J Liu, JP Schroeder, D Weinshenker, DM Duong, NT Seyfried, Y Li, P Jin, AP Wingo, TS Wingo 08/16/2023 Molecular neurobiology
L Lin, X Liu, X Cheng, Y Li, M Gearing, A Levey, X Huang, Y Li, P Jin, X Li 05/01/2023 Alzheimer's & dementia : the journal of the Alzheimer's Association
H Palma-Gudiel, L Yu, Z Huo, J Yang, Y Wang, T Gu, C Gao, PL De Jager, P Jin, DA Bennett, J Zhao 04/01/2023 bioRxiv : the preprint server for biology
S Sharma, W Ma, KJ Ressler, T Anderson, DC Li, P Jin, SL Gourley, Z Qin 03/10/2023 Highly synchronized cortical circuit dynamics mediate spontaneous pain in mice.
The Journal of clinical investigation
W Ding, L Fischer, Q Chen, Z Li, L Yang, Z You, K Hu, X Wu, X Zhou, W Chao, P Hu, TM Dagnew, DM Dubreuil, S Wang, S Xia, C Bao, S Zhu, L Chen, C Wang, B Wainger, P Jin, J Mao, G Feng, MT Harnett, S Shen 03/01/2023 Age-Dependent Dysregulation of APP in Neuronal and Skin Cells from Fragile X Individuals.
Cells
G Cencelli, L Pacini, A De Luca, I Messia, A Gentile, Y Kang, V Nobile, E Tabolacci, P Jin, MG Farace, C Bagni 02/27/2023 Human molecular genetics
Y Jin, K Su, HE Kong, W Ma, Z Wang, Y Li, R Li, EG Allen, H Wu, P Jin 01/06/2023 Frontiers in genetics
R Satange, P Jin, MH Hou, AB Rode 01/01/2023 Analyzing mRNA Epigenetic Sequencing Data with TRESS.
Methods in molecular biology (Clifton, N.J.)
Z Guo, AM Shafik, P Jin, Z Wu, H Wu 01/01/2023 Proceedings of the National Academy of Sciences of the United States of America
YH Jung, HV Wang, D Ruiz, BJ Bixler, H Linsenbaum, JF Xiang, S Forestier, AM Shafik, P Jin, VG Corces 12/13/2022 Science advances
Q Liu, K Zhang, Y Kang, Y Li, P Deng, Y Li, Y Tian, Q Sun, Y Tang, K Xu, Y Zhou, JL Wang, J Guo, JD Li, K Xia, Q Meng, EG Allen, Z Wen, Z Li, H Jiang, L Shen, R Duan, B Yao, B Tang, P Jin, Y Pan 11/25/2022 Differential RNA methylation analysis for MeRIP-seq data under general experimental design.
Bioinformatics (Oxford, England)
Z Guo, AM Shafik, P Jin, H Wu 10/14/2022 Altered hydroxymethylome in the substantia nigra of Parkinson's disease.
Human molecular genetics
S Min, Q Xu, L Qin, Y Li, Z Li, C Chen, H Wu, J Han, X Zhu, P Jin, B Tang 10/10/2022 Epitranscriptomic dynamics in brain development and disease.
Molecular psychiatry
AM Shafik, EG Allen, P Jin 09/01/2022 American journal of medical genetics. Part A
JV Reyes Diaz, Y Jin, K Garber, KM Cossen, Y Li, P Jin, H Li, JN Ham 08/01/2022 Descriptive analysis of seizures and comorbidities associated with fragile X syndrome.
Molecular genetics & genomic medicine
I Albizua, K Charen, L Shubeck, A Talboy, E Berry-Kravis, WE Kaufmann, JL Stallworth, KT Drazba, CA Erickson, JA Sweeney, N Tartaglia, SF Warren, R Hagerman, SL Sherman, ST Warren, P Jin, EG Allen 08/01/2022 Identification of PSMB5 as a genetic modifier of fragile X-associated tremor/ataxia syndrome.
Proceedings of the National Academy of Sciences of the United States of America
HE Kong, J Lim, A Linsalata, Y Kang, I Malik, EG Allen, Y Cao, L Shubeck, R Johnston, Y Huang, Y Gu, X Guo, ME Zwick, Z Qin, TS Wingo, J Juncos, DL Nelson, MP Epstein, DJ Cutler, PK Todd, SL Sherman, ST Warren, P Jin 05/31/2022 Across Dimensions: Developing 2D and 3D Human iPSC-Based Models of Fragile X Syndrome.
Cells
A Lee, J Xu, Z Wen, P Jin 05/24/2022 Dysregulated mitochondrial and cytosolic tRNA m1A methylation in Alzheimer's disease.
Human molecular genetics
AM Shafik, H Zhou, J Lim, B Dickinson, P Jin 05/19/2022 Briefings in bioinformatics
W Ma, S Sharma, P Jin, SL Gourley, ZS Qin 05/13/2022 Cell-free DNA methylation as a potential biomarker in brain disorders.
Epigenomics
Y Jin, EG Allen, P Jin 04/01/2022 Journal of personalized medicine
J Deng, XX Guan, YB Zhu, HT Deng, GX Li, YC Guo, P Jin, RH Duan, W Huang 03/02/2022 Brain microRNAs are associated with variation in cognitive trajectory in advanced age.
Translational psychiatry
AP Wingo, M Wang, J Liu, MS Breen, HS Yang, B Tang, JA Schneider, NT Seyfried, JJ Lah, AI Levey, DA Bennett, P Jin, PL De Jager, TS Wingo 02/01/2022 Disease category-specific annotation of variants using an ensemble learning framework.
Briefings in bioinformatics
Z Cao, Y Huang, R Duan, P Jin, ZS Qin, S Zhang 01/17/2022 Stephen T. Warren, Ph.D. (1953-2021): A remembrance.
American journal of human genetics
DL Nelson, J Clark, K Garber, T Glover, T Hassold, P Jin, HT Orr, SL Sherman, H Zoghbi, KL Warren 01/06/2022 Molecular neurobiology
XR Huang, BS Tang, P Jin, JF Guo 01/01/2022 Stress modulates Ahi1-dependent nuclear localization of ten-eleven translocation protein 2.
Human molecular genetics
Q Zhang, Q Hu, J Wang, Z Miao, Z Li, Y Zhao, B Wan, EG Allen, M Sun, P Jin, X Xu 11/01/2021 Human molecular genetics
C Meng, L Gu, Y Li, R Li, Y Cao, Z Li, EG Allen, D Zhu, P Jin 10/13/2021 Nature neuroscience
Y Kang, Y Zhou, Y Li, Y Han, J Xu, W Niu, Z Li, S Liu, H Feng, W Huang, R Duan, T Xu, N Raj, F Zhang, J Dou, C Xu, H Wu, GJ Bassell, ST Warren, EG Allen, P Jin, Z Wen 10/01/2021 Remembering Stephen T. Warren, a pillar of neurogenetics (1953-2021).
Nature neuroscience
P Jin, GJ Bassell 10/01/2021 Detecting m6A methylation regions from Methylated RNA Immunoprecipitation Sequencing.
Bioinformatics (Oxford, England)
Z Guo, AM Shafik, P Jin, Z Wu, H Wu 09/29/2021 Nucleic acids research
CR Jhan, R Satange, SC Wang, JY Zeng, YC Horng, P Jin, S Neidle, MH Hou 09/20/2021 Fertility and sterility
CE Trevino, JC Rounds, K Charen, L Shubeck, HS Hipp, JB Spencer, HR Johnston, DJ Cutler, ME Zwick, MP Epstein, A Murray, JN Macpherson, M Mila, L Rodriguez-Revenga, E Berry-Kravis, DA Hall, MA Leehey, Y Liu, C Welt, ST Warren, SL Sherman, P Jin, EG Allen 09/01/2021 Nature communications
Y Huang, X Sun, H Jiang, S Yu, C Robins, MJ Armstrong, R Li, Z Mei, X Shi, ES Gerasimov, PL De Jager, DA Bennett, AP Wingo, P Jin, TS Wingo, ZS Qin 07/22/2021 Downregulation of TOP2 modulates neurodegeneration caused by GGGGCC expanded repeats.
Human molecular genetics
B Jiao, M Wang, H Feng, H Bao, F Zhang, H Wu, J Wang, B Tang, P Jin, L Shen 05/29/2021 Human molecular genetics
KE Shelly, NR Candelaria, Z Li, EG Allen, P Jin, DL Nelson 05/29/2021 Important Correlates of Purpose in Life Identified Through a Machine Learning Approach.
The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry
Z Mei, A Lori, SM Vattathil, PA Boyle, B Bradley, P Jin, DA Bennett, TS Wingo, AP Wingo 05/01/2021 Ten-eleven translocation protein 1 modulates medulloblastoma progression.
Genome biology
H Kim, Y Kang, Y Li, L Chen, L Lin, ND Johnson, D Zhu, MH Robinson, L McSwain, BG Barwick, X Yuan, X Liao, J Zhao, Z Zhang, Q Shu, J Chen, EG Allen, AM Kenney, RC Castellino, EG Van Meir, KN Conneely, PM Vertino, P Jin, J Li 04/29/2021 Cell reports
N Raj, ZT McEachin, W Harousseau, Y Zhou, F Zhang, ME Merritt-Garza, JM Taliaferro, M Kalinowska, SG Marro, CM Hales, E Berry-Kravis, MW Wolf-Ochoa, V Martinez-Cerdeño, M Wernig, L Chen, E Klann, ST Warren, P Jin, Z Wen, GJ Bassell 04/13/2021 Nature communications
G Song, G Wang, X Luo, Y Cheng, Q Song, J Wan, C Moore, H Song, P Jin, J Qian, H Zhu 02/23/2021 Nature communications
G Song, G Wang, X Luo, Y Cheng, Q Song, J Wan, C Moore, H Song, P Jin, J Qian, H Zhu 02/04/2021 Genome biology
AM Shafik, F Zhang, Z Guo, Q Dai, K Pajdzik, Y Li, Y Kang, B Yao, H Wu, C He, EG Allen, R Duan, P Jin 01/05/2021 Frontiers in cell and developmental biology
W Ren, C Xu, FJ Zheng, TT Lin, P Jin, Y Zhang, WW Guo, CH Liu, XY Zhou, LL Wang, Y Wang, H Zhao, SM Yang 01/01/2021 Therapeutic Development for CGG Repeat Expansion-Associated Neurodegeneration.
Frontiers in cellular neuroscience
K Xu, Y Li, EG Allen, P Jin 01/01/2021 Neuropeptides Modulate Local Astrocytes to Regulate Adult Hippocampal Neural Stem Cells.
Neuron
B Asrican, J Wooten, YD Li, L Quintanilla, F Zhang, C Wander, H Bao, CY Yeh, YJ Luo, R Olsen, SA Lim, J Hu, P Jin, J Song 10/28/2020 Neurobiology of disease
Y Lin, J Xue, J Deng, H He, S Luo, J Chen, J Li, L Yu, J Zhao, J Chen, EG Allen, P Jin, R Duan 09/01/2020 Publisher Correction: Integrated analysis of a compendium of RNA-Seq datasets for splicing factors.
Scientific data
P Yu, J Li, SP Deng, F Zhang, PN Grozdanov, EWM Chin, SD Martin, L Vergnes, MS Islam, D Sun, JM LaSalle, SL McGee, E Goh, CC MacDonald, P Jin 08/07/2020 Integrated analysis of a compendium of RNA-Seq datasets for splicing factors.
Scientific data
P Yu, J Li, SP Deng, F Zhang, PN Grozdanov, EWM Chin, SD Martin, L Vergnes, MS Islam, D Sun, JM LaSalle, SL McGee, E Goh, CC MacDonald, P Jin 06/16/2020 Robust partial reference-free cell composition estimation from tissue expression.
Bioinformatics (Oxford, England)
Z Li, Z Guo, Y Cheng, P Jin, H Wu 06/01/2020 Molecular genetics & genomic medicine
F Gao, W Huang, Y You, J Huang, J Zhao, J Xue, H Kang, Y Zhu, Z Hu, EG Allen, P Jin, K Xia, R Duan 06/01/2020 Epigenetics
ND Johnson, L Huang, R Li, Y Li, Y Yang, HR Kim, C Grant, H Wu, EA Whitsel, DP Kiel, AA Baccarelli, P Jin, JM Murabito, KN Conneely 03/01/2020 Regulatory annotation of genomic intervals based on tissue-specific expression QTLs.
Bioinformatics (Oxford, England)
T Xu, P Jin, ZS Qin 02/01/2020 Dynamic N6-methyladenosine RNA methylation in brain and diseases.
Epigenomics
AM Shafik, EG Allen, P Jin 02/01/2020 Journal of ovarian research
L Cheng, K Zhang, Y Qing, D Li, M Cui, P Jin, T Xu 01/22/2020 A comprehensive review of computational prediction of genome-wide features.
Briefings in bioinformatics
T Xu, X Zheng, B Li, P Jin, Z Qin, H Wu 01/17/2020 Grainyhead-like 2 as a double-edged sword in development and cancer.
American journal of translational research
J He, C Feng, H Zhu, S Wu, P Jin, T Xu 01/01/2020 Metabolic Alterations in FMR1 Premutation Carriers.
Frontiers in molecular biosciences
Y Cao, Y Peng, HE Kong, EG Allen, P Jin 01/01/2020 Ethnicity-specific and overlapping alterations of brain hydroxymethylome in Alzheimer's disease.
Human molecular genetics
L Qin, Q Xu, Z Li, L Chen, Y Li, N Yang, Z Liu, J Guo, L Shen, EG Allen, C Chen, C Ma, H Wu, X Zhu, P Jin, B Tang 01/01/2020 Altered 5-Hydroxymethylcytosine Landscape in Primary Gastric Adenocarcinoma.
DNA and cell biology
H Liu, T Xu, Y Cheng, MH Jin, MY Chang, Q Shu, EG Allen, P Jin, X Wang 12/01/2019 Diverse and dynamic DNA modifications in brain and diseases.
Human molecular genetics
MJ Armstrong, Y Jin, EG Allen, P Jin 11/21/2019 Dissecting differential signals in high-throughput data from complex tissues.
Bioinformatics (Oxford, England)
Z Li, Z Wu, P Jin, H Wu 10/15/2019 Neurobiology of disease
H He, W Huang, R Wang, Y Lin, Y Guo, J Deng, H Deng, Y Zhu, EG Allen, P Jin, R Duan 10/01/2019 Current biology : CB
PK Byun, C Zhang, B Yao, J Wardwell-Ozgo, D Terry, P Jin, K Moberg 09/09/2019 Biological psychiatry
Y Cheng, P Jin 08/15/2019 Rare variants in MYH15 modify amyotrophic lateral sclerosis risk.
Human molecular genetics
H Kim, J Lim, H Bao, B Jiao, SM Canon, MP Epstein, K Xu, J Jiang, J Parameswaran, Y Li, KH Moberg, JE Landers, C Fournier, EG Allen, JD Glass, TS Wingo, P Jin 07/15/2019 Expansion of Human-Specific GGC Repeat in Neuronal Intranuclear Inclusion Disease-Related Disorders.
American journal of human genetics
Y Tian, JL Wang, W Huang, S Zeng, B Jiao, Z Liu, Z Chen, Y Li, Y Wang, HX Min, XJ Wang, Y You, RX Zhang, XY Chen, F Yi, YF Zhou, HY Long, CJ Zhou, X Hou, JP Wang, B Xie, F Liang, ZY Yang, QY Sun, EG Allen, AM Shafik, HE Kong, JF Guo, XX Yan, ZM Hu, K Xia, H Jiang, HW Xu, RH Duan, P Jin, BS Tang, L Shen 07/03/2019 Disease prediction by cell-free DNA methylation.
Briefings in bioinformatics
H Feng, P Jin, H Wu 03/25/2019 Human molecular genetics
HE Kong, J Lim, F Zhang, L Huang, Y Gu, DL Nelson, EG Allen, P Jin 03/15/2019 Reversing Behavioral, Neuroanatomical, and Germline Influences of Intergenerational Stress.
Biological psychiatry
HS Aoued, S Sannigrahi, N Doshi, FG Morrison, H Linsenbaum, SC Hunter, H Walum, J Baman, B Yao, P Jin, KJ Ressler, BG Dias 02/01/2019 Application of Drosophila Model Toward Understanding the Molecular Basis of Fragile X Syndrome.
Methods in molecular biology (Clifton, N.J.)
HE Kong, J Lim, P Jin 01/01/2019 Ten-Eleven Translocation Proteins Modulate the Response to Environmental Stress in Mice.
Cell reports
Y Cheng, M Sun, L Chen, Y Li, L Lin, B Yao, Z Li, Z Wang, J Chen, Z Miao, N Xin, L Huang, EG Allen, H Wu, X Xu, P Jin 12/11/2018 Nature neuroscience
Y Cheng, ZM Wang, W Tan, X Wang, Y Li, B Bai, Y Li, SF Zhang, HL Yan, ZL Chen, CM Liu, TW Mi, S Xia, Z Zhou, A Liu, GB Tang, C Liu, ZJ Dai, YY Wang, H Wang, X Wang, Y Kang, L Lin, Z Chen, N Xie, Q Sun, W Xie, J Peng, D Chen, ZQ Teng, P Jin 12/01/2018 Human molecular genetics
F Zhang, Y Kang, M Wang, Y Li, T Xu, W Yang, H Song, H Wu, Q Shu, P Jin 11/15/2018 Molecular cell
B Yao, Y Li, Z Wang, L Chen, M Poidevin, C Zhang, L Lin, F Wang, H Bao, B Jiao, J Lim, Y Cheng, L Huang, BL Phillips, T Xu, R Duan, KH Moberg, H Wu, P Jin 09/06/2018 5-Hydroxymethylcytosine alterations in the human postmortem brains of autism spectrum disorder.
Human molecular genetics
Y Cheng, Z Li, S Manupipatpong, L Lin, X Li, T Xu, YH Jiang, Q Shu, H Wu, P Jin 09/01/2018 GigaScience
X Sun, J Gao, P Jin, C Eng, EG Burchard, TH Beaty, I Ruczinski, RA Mathias, K Barnes, F Wang, ZS Qin 06/01/2018 Genome biology
B Yao, P Jin 04/10/2018 Developing DNA methylation-based diagnostic biomarkers.
Journal of genetics and genomics = Yi chuan xue bao
H Kim, X Wang, P Jin 02/20/2018 Medical genetics: Towards precision medicine.
Journal of genetics and genomics = Yi chuan xue bao
P Jin 02/20/2018 Piperine ameliorates SCA17 neuropathology by reducing ER stress.
Molecular neurodegeneration
J Guo, Y Cui, Q Liu, Y Yang, Y Li, L Weng, B Tang, P Jin, XJ Li, S Yang, S Li 01/30/2018 Epitranscriptomic m6A Regulation of Axon Regeneration in the Adult Mammalian Nervous System.
Neuron
YL Weng, X Wang, R An, J Cassin, C Vissers, Y Liu, Y Liu, T Xu, X Wang, SZH Wong, J Joseph, LC Dore, Q Dong, W Zheng, P Jin, H Wu, B Shen, X Zhuang, C He, K Liu, H Song, GL Ming 01/17/2018 Temporal Control of Mammalian Cortical Neurogenesis by m6A Methylation.
Cell
KJ Yoon, FR Ringeling, C Vissers, F Jacob, M Pokrass, D Jimenez-Cyrus, Y Su, NS Kim, Y Zhu, L Zheng, S Kim, X Wang, LC Doré, P Jin, S Regot, X Zhuang, S Canzar, C He, GL Ming, H Song 11/02/2017 DNA N6-methyladenine is dynamically regulated in the mouse brain following environmental stress.
Nature communications
B Yao, Y Cheng, Z Wang, Y Li, L Chen, L Huang, W Zhang, D Chen, H Wu, B Tang, P Jin 10/24/2017 Cell stem cell
KJ Yoon, G Song, X Qian, J Pan, D Xu, HS Rho, NS Kim, C Habela, L Zheng, F Jacob, F Zhang, EM Lee, WK Huang, FR Ringeling, C Vissers, C Li, L Yuan, K Kang, S Kim, J Yeo, Y Cheng, S Liu, Z Wen, CF Qin, Q Wu, KM Christian, H Tang, P Jin, Z Xu, J Qian, H Zhu, H Song, GL Ming 09/07/2017 Zika virus directly infects peripheral neurons and induces cell death.
Nature neuroscience
Y Oh, F Zhang, Y Wang, EM Lee, IY Choi, H Lim, F Mirakhori, R Li, L Huang, T Xu, H Wu, C Li, CF Qin, Z Wen, QF Wu, H Tang, Z Xu, P Jin, H Song, GL Ming, G Lee 09/01/2017 Fat mass and obesity-associated (FTO) protein regulates adult neurogenesis.
Human molecular genetics
L Li, L Zang, F Zhang, J Chen, H Shen, L Shu, F Liang, C Feng, D Chen, H Tao, T Xu, Z Li, Y Kang, H Wu, L Tang, P Zhang, P Jin, Q Shu, X Li 07/01/2017 CRISPR/Cas9-mediated gene editing ameliorates neurotoxicity in mouse model of Huntington's disease.
The Journal of clinical investigation
S Yang, R Chang, H Yang, T Zhao, Y Hong, HE Kong, X Sun, Z Qin, P Jin, S Li, XJ Li 06/30/2017 Ten-eleven translocation 2 interacts with forkhead box O3 and regulates adult neurogenesis.
Nature communications
X Li, B Yao, L Chen, Y Kang, Y Li, Y Cheng, L Li, L Lin, Z Wang, M Wang, F Pan, Q Dai, W Zhang, H Wu, Q Shu, Z Qin, C He, M Xu, P Jin 06/29/2017 A genome-wide profiling of brain DNA hydroxymethylation in Alzheimer's disease.
Alzheimer's & dementia : the journal of the Alzheimer's Association
J Zhao, Y Zhu, J Yang, L Li, H Wu, PL De Jager, P Jin, DA Bennett 06/01/2017 Tet2 loss leads to hypermutagenicity in haematopoietic stem/progenitor cells.
Nature communications
F Pan, TS Wingo, Z Zhao, R Gao, H Makishima, G Qu, L Lin, M Yu, JR Ortega, J Wang, A Nazha, L Chen, B Yao, C Liu, S Chen, O Weeks, H Ni, BL Phillips, S Huang, J Wang, C He, GM Li, T Radivoyevitch, I Aifantis, JP Maciejewski, FC Yang, P Jin, M Xu 04/25/2017 Frontiers in cellular neuroscience
HE Kong, J Zhao, S Xu, P Jin, Y Jin 01/01/2017 Genome biology
L Chen, P Jin, ZS Qin 12/06/2016 Sex-specific hippocampal 5-hydroxymethylcytosine is disrupted in response to acute stress.
Neurobiology of disease
LA Papale, S Li, A Madrid, Q Zhang, L Chen, P Chopra, P Jin, S Keleş, RS Alisch 12/01/2016 Distinctive Klf4 mutants determine preference for DNA methylation status.
Nucleic acids research
H Hashimoto, D Wang, AN Steves, P Jin, RM Blumenthal, X Zhang, X Cheng 12/01/2016 Structural dynamics control the MicroRNA maturation pathway.
Nucleic acids research
P Dallaire, H Tan, K Szulwach, C Ma, P Jin, F Major 11/16/2016 Histone deacetylase 3 associates with MeCP2 to regulate FOXO and social behavior.
Nature neuroscience
A Nott, J Cheng, F Gao, YT Lin, E Gjoneska, T Ko, P Minhas, AV Zamudio, J Meng, F Zhang, P Jin, LH Tsai 11/01/2016 Experimental and molecular pathology
JA Gross, C Nagy, L Lin, É Bonneil, M Maheu, P Thibault, N Mechawar, P Jin, G Turecki 10/14/2016 Molecular signatures associated with ZIKV exposure in human cortical neural progenitors.
Nucleic acids research
F Zhang, C Hammack, SC Ogden, Y Cheng, EM Lee, Z Wen, X Qian, HN Nguyen, Y Li, B Yao, M Xu, T Xu, L Chen, Z Wang, H Feng, WK Huang, KJ Yoon, C Shan, L Huang, Z Qin, KM Christian, PY Shi, M Xu, M Xia, W Zheng, H Wu, H Song, H Tang, GL Ming, P Jin 10/14/2016 Epigenetic mechanisms in neurogenesis.
Nature reviews. Neuroscience
B Yao, KM Christian, C He, P Jin, GL Ming, H Song 09/01/2016 Human molecular genetics
AI Bernstein, Y Lin, RC Street, L Lin, Q Dai, L Yu, H Bao, M Gearing, JJ Lah, PT Nelson, C He, AI Levey, JG Mullé, R Duan, P Jin 06/15/2016 Human molecular genetics
M Sun, MM Song, B Wei, Q Gao, L Li, B Yao, L Chen, L Lin, Q Dai, X Zhou, J Tao, J Chen, C He, P Jin, Z Xu 06/01/2016 Genome-wide alteration of 5-hydroxymenthylcytosine in a mouse model of Alzheimer's disease.
BMC genomics
L Shu, W Sun, L Li, Z Xu, L Lin, P Xie, H Shen, L Huang, Q Xu, P Jin, X Li 05/20/2016 Brain-Region-Specific Organoids Using Mini-bioreactors for Modeling ZIKV Exposure.
Cell
X Qian, HN Nguyen, MM Song, C Hadiono, SC Ogden, C Hammack, B Yao, GR Hamersky, F Jacob, C Zhong, KJ Yoon, W Jeang, L Lin, Y Li, J Thakor, DA Berg, C Zhang, E Kang, M Chickering, D Nauen, CY Ho, Z Wen, KM Christian, PY Shi, BJ Maher, H Wu, P Jin, H Tang, H Song, GL Ming 05/19/2016 Zika Virus Infects Human Cortical Neural Progenitors and Attenuates Their Growth.
Cell stem cell
H Tang, C Hammack, SC Ogden, Z Wen, X Qian, Y Li, B Yao, J Shin, F Zhang, EM Lee, KM Christian, RA Didier, P Jin, H Song, GL Ming 05/05/2016 DNA methylation dynamics in neurogenesis.
Epigenomics
Z Wang, B Tang, Y He, P Jin 03/01/2016 Neurobiology of disease
S Li, LA Papale, Q Zhang, A Madrid, L Chen, P Chopra, S Keleş, P Jin, RS Alisch 02/01/2016 eLife
J Weber, H Bao, C Hartlmüller, Z Wang, A Windhager, R Janowski, T Madl, P Jin, D Niessing 01/08/2016 Lin28A Binds Active Promoters and Recruits Tet1 to Regulate Gene Expression.
Molecular cell
Y Zeng, B Yao, J Shin, L Lin, N Kim, Q Song, S Liu, Y Su, JU Guo, L Huang, J Wan, H Wu, J Qian, X Cheng, H Zhu, GL Ming, P Jin, H Song 01/07/2016 Frontiers in genetics
JA Gross, C Nagy, L Lin, É Bonneil, M Maheu, P Thibault, N Mechawar, P Jin, G Turecki 01/01/2016 The Drosophila Helicase MLE Targets Hairpin Structures in Genomic Transcripts.
PLoS genetics
S Cugusi, Y Li, P Jin, JC Lucchesi 01/01/2016 Small Molecules Efficiently Reprogram Human Astroglial Cells into Functional Neurons.
Cell stem cell
L Zhang, JC Yin, H Yeh, NX Ma, G Lee, XA Chen, Y Wang, L Lin, L Chen, P Jin, GY Wu, G Chen 12/03/2015 DICER1 and microRNA regulation in post-traumatic stress disorder with comorbid depression.
Nature communications
AP Wingo, LM Almli, JS Stevens, T Klengel, M Uddin, Y Li, AC Bustamante, A Lori, N Koen, DJ Stein, AK Smith, AE Aiello, KC Koenen, DE Wildman, S Galea, B Bradley, EB Binder, P Jin, G Gibson, KJ Ressler 12/03/2015 Nucleic acids research
H Wu, T Xu, H Feng, L Chen, B Li, B Yao, Z Qin, P Jin, KN Conneely 12/02/2015 Combined Loss of Tet1 and Tet2 Promotes B Cell, but Not Myeloid Malignancies, in Mice.
Cell reports
Z Zhao, L Chen, MM Dawlaty, F Pan, O Weeks, Y Zhou, Z Cao, H Shi, J Wang, L Lin, S Chen, W Yuan, Z Qin, H Ni, SD Nimer, FC Yang, R Jaenisch, P Jin, M Xu 11/24/2015 Altering 5-hydroxymethylcytosine modification impacts ischemic brain injury.
Human molecular genetics
Z Miao, Y He, N Xin, M Sun, L Chen, L Lin, J Li, J Kong, P Jin, X Xu 10/15/2015 The Journal of biological chemistry
J Zeng, R Mi, Y Wang, Y Li, L Lin, B Yao, L Song, I van Die, AB Chapman, RD Cummings, P Jin, T Ju 07/31/2015 Developmental cell
C Zhang, BS Robinson, W Xu, L Yang, B Yao, H Zhao, PK Byun, P Jin, A Veraksa, KH Moberg 07/27/2015 DNA methylation and hydroxymethylation in stem cells.
Cell biochemistry and function
Y Cheng, N Xie, P Jin, T Wang 06/01/2015 5-Hydroxymethylcytosine: A new player in brain disorders?
Experimental neurology
Y Cheng, A Bernstein, D Chen, P Jin 06/01/2015 Molecular and cellular biology
J Hanus, H Zhang, DH Chen, Q Zhou, P Jin, Q Liu, S Wang 06/01/2015 Role of Tet1 and 5-hydroxymethylcytosine in cocaine action.
Nature neuroscience
J Feng, N Shao, KE Szulwach, V Vialou, J Huynh, C Zhong, T Le, D Ferguson, ME Cahill, Y Li, JW Koo, E Ribeiro, B Labonte, BM Laitman, D Estey, V Stockman, P Kennedy, T Couroussé, I Mensah, G Turecki, KF Faull, GL Ming, H Song, G Fan, P Casaccia, L Shen, P Jin, EJ Nestler 04/01/2015 Base-resolution methylation patterns accurately predict transcription factor bindings in vivo.
Nucleic acids research
T Xu, B Li, M Zhao, KE Szulwach, RC Street, L Lin, B Yao, F Zhang, P Jin, H Wu, ZS Qin 03/11/2015 Cancer cell
L Jin, D Li, GN Alesi, J Fan, HB Kang, Z Lu, TJ Boggon, P Jin, H Yi, ER Wright, D Duong, NT Seyfried, R Egnatchik, RJ DeBerardinis, KR Magliocca, C He, ML Arellano, HJ Khoury, DM Shin, FR Khuri, S Kang 02/09/2015 Proceedings of the National Academy of Sciences of the United States of America
LK Myrick, PY Deng, H Hashimoto, YM Oh, Y Cho, MJ Poidevin, JA Suhl, J Visootsak, V Cavalli, P Jin, X Cheng, ST Warren, VA Klyachko 01/27/2015 Small-molecule screening using Drosophila models of human neurological disorders.
Methods in molecular biology (Clifton, N.J.)
M Poidevin, F Zhang, P Jin 01/01/2015 Nature communications
H Li, X Zhong, KF Chau, NJ Santistevan, W Guo, G Kong, X Li, M Kadakia, J Masliah, J Chi, P Jin, J Zhang, X Zhao, Q Chang 11/25/2014 Human molecular genetics
JN Galloway, C Shaw, P Yu, D Parghi, M Poidevin, P Jin, DL Nelson 11/15/2014 Environmental enrichment modulates 5-hydroxymethylcytosine dynamics in hippocampus.
Genomics
H Irier, RC Street, R Dave, L Lin, C Cai, TH Davis, B Yao, Y Cheng, P Jin 11/01/2014 Human molecular genetics
W Zhang, Y Cheng, Y Li, Z Chen, P Jin, D Chen 10/01/2014 Towards understanding RNA-mediated neurological disorders.
Journal of genetics and genomics = Yi chuan xue bao
R Duan, S Sharma, Q Xia, K Garber, P Jin 09/20/2014 AGO3 Slicer activity regulates mitochondria-nuage localization of Armitage and piRNA amplification.
The Journal of cell biology
H Huang, Y Li, KE Szulwach, G Zhang, P Jin, D Chen 07/21/2014 Unlocking epigenetic codes in neurogenesis.
Genes & development
B Yao, P Jin 06/15/2014 Human molecular genetics
L Lin, CM Hales, K Garber, P Jin 06/15/2014 Stem cell reports
G Zhu, Y Li, F Zhu, T Wang, W Jin, W Mu, W Lin, W Tan, W Li, RC Street, S Peng, J Zhang, Y Feng, ST Warren, Q Sun, P Jin, D Chen 03/11/2014 Human molecular genetics
B Yao, L Lin, RC Street, ZA Zalewski, JN Galloway, H Wu, DL Nelson, P Jin 02/15/2014 Cytosine modifications in neurodevelopment and diseases.
Cellular and molecular life sciences : CMLS
B Yao, P Jin 02/01/2014 Genome-wide antagonism between 5-hydroxymethylcytosine and DNA methylation in the adult mouse brain.
Frontiers in biology
JU Guo, KE Szulwach, Y Su, Y Li, B Yao, Z Xu, JH Shin, B Xie, Y Gao, GL Ming, P Jin, H Song 02/01/2014 Integrating DNA methylation dynamics into a framework for understanding epigenetic codes.
BioEssays : news and reviews in molecular, cellular and developmental biology
KE Szulwach, P Jin 01/01/2014 Journal of neurodevelopmental disorders
SL Sherman, EC Curnow, CA Easley, P Jin, RK Hukema, MI Tejada, R Willemsen, K Usdin 01/01/2014 Toward pluripotency by reprogramming: mechanisms and application.
Protein & cell
T Wang, ST Warren, P Jin 11/01/2013 Probing the microRNA pathway with small molecules.
Bioorganic & medicinal chemistry
Y Li, P Ji, P Jin 10/15/2013 U1 small nuclear ribonucleoprotein complex and RNA splicing alterations in Alzheimer's disease.
Proceedings of the National Academy of Sciences of the United States of America
B Bai, CM Hales, PC Chen, Y Gozal, EB Dammer, JJ Fritz, X Wang, Q Xia, DM Duong, C Street, G Cantero, D Cheng, DR Jones, Z Wu, Y Li, I Diner, CJ Heilman, HD Rees, H Wu, L Lin, KE Szulwach, M Gearing, EJ Mufson, DA Bennett, TJ Montine, NT Seyfried, TS Wingo, YE Sun, P Jin, J Hanfelt, DM Willcock, A Levey, JJ Lah, J Peng 10/08/2013 TET1 plays an essential oncogenic role in MLL-rearranged leukemia.
Proceedings of the National Academy of Sciences of the United States of America
H Huang, X Jiang, Z Li, Y Li, CX Song, C He, M Sun, P Chen, S Gurbuxani, J Wang, GM Hong, AG Elkahloun, S Arnovitz, J Wang, K Szulwach, L Lin, C Street, M Wunderlich, M Dawlaty, MB Neilly, R Jaenisch, FC Yang, JC Mulloy, P Jin, PP Liu, JD Rowley, M Xu, C He, J Chen 07/16/2013 Nature cell biology
T Wang, H Wu, Y Li, KE Szulwach, L Lin, X Li, IP Chen, IS Goldlust, SJ Chamberlain, A Dodd, H Gong, G Ananiev, JW Han, YS Yoon, MK Rudd, M Yu, CX Song, C He, Q Chang, ST Warren, P Jin 06/01/2013 Proceedings of the National Academy of Sciences of the United States of America
Z Xu, M Poidevin, X Li, Y Li, L Shu, DL Nelson, H Li, CM Hales, M Gearing, TS Wingo, P Jin 05/07/2013 Genome-wide profiling of 5-formylcytosine reveals its roles in epigenetic priming.
Cell
CX Song, KE Szulwach, Q Dai, Y Fu, SQ Mao, L Lin, C Street, Y Li, M Poidevin, H Wu, J Gao, P Liu, L Li, GL Xu, P Jin, C He 04/25/2013 Tet-mediated covalent labelling of 5-methylcytosine for its genome-wide detection and sequencing.
Nature communications
L Zhang, KE Szulwach, GC Hon, CX Song, B Park, M Yu, X Lu, Q Dai, X Wang, CR Street, H Tan, JH Min, B Ren, P Jin, C He 01/01/2013 Nature communications
T Hitosugi, L Zhou, J Fan, S Elf, L Zhang, J Xie, Y Wang, TL Gu, M Alečković, G LeRoy, Y Kang, HB Kang, JH Seo, C Shan, P Jin, W Gong, S Lonial, ML Arellano, HJ Khoury, GZ Chen, DM Shin, FR Khuri, TJ Boggon, S Kang, C He, J Chen 01/01/2013 Stem cell reports
AM Singh, J Chappell, R Trost, L Lin, T Wang, J Tang, BK Matlock, KP Weller, H Wu, S Zhao, P Jin, S Dalton 01/01/2013 Human molecular genetics
T Wang, Q Pan, L Lin, KE Szulwach, CX Song, C He, H Wu, ST Warren, P Jin, R Duan, X Li 12/15/2012 Epigenetics-Based Therapeutics for Neurodegenerative Disorders.
Current translational geriatrics and experimental gerontology reports
Z Xu, H Li, P Jin 12/01/2012 SRPK2 phosphorylates tau and mediates the cognitive defects in Alzheimer's disease.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Y Hong, CB Chan, IS Kwon, X Li, M Song, HP Lee, X Liu, P Sompol, P Jin, HG Lee, SP Yu, K Ye 11/28/2012 Phosphoglycerate mutase 1 coordinates glycolysis and biosynthesis to promote tumor growth.
Cancer cell
T Hitosugi, L Zhou, S Elf, J Fan, HB Kang, JH Seo, C Shan, Q Dai, L Zhang, J Xie, TL Gu, P Jin, M Alečković, G LeRoy, Y Kang, JA Sudderth, RJ DeBerardinis, CH Luan, GZ Chen, S Muller, DM Shin, TK Owonikoko, S Lonial, ML Arellano, HJ Khoury, FR Khuri, BH Lee, K Ye, TJ Boggon, S Kang, C He, J Chen 11/13/2012 Selective capture of 5-hydroxymethylcytosine from genomic DNA.
Journal of visualized experiments : JoVE
Y Li, CX Song, C He, P Jin 10/05/2012 Dynamics of DNA methylation in aging and Alzheimer's disease.
DNA and cell biology
HA Irier, P Jin 10/01/2012 Stable isotope labeling with amino acids in Drosophila for quantifying proteins and modifications.
Journal of proteome research
P Xu, H Tan, DM Duong, Y Yang, J Kupsco, KH Moberg, H Li, P Jin, J Peng 09/07/2012 5-Hydroxymethylcytosine (5-hmC) Specific Enrichment.
Bio-protocol
KE Szulwach, CX Song, C He, P Jin 08/05/2012 RNA-mediated neurodegeneration in fragile X-associated tremor/ataxia syndrome.
Brain research
Y Li, P Jin 06/26/2012 Iron homeostasis regulates the activity of the microRNA pathway through poly(C)-binding protein 2.
Cell metabolism
Y Li, L Lin, Z Li, X Ye, K Xiong, B Aryal, Z Xu, Z Paroo, Q Liu, C He, P Jin 06/06/2012 Role of noncoding RNAs in trinucleotide repeat neurodegenerative disorders.
Experimental neurology
H Tan, Z Xu, P Jin 06/01/2012 Human molecular genetics
A Qurashi, H Liu, L Ray, DL Nelson, R Duan, P Jin 05/01/2012 Retrotransposon activation contributes to fragile X premutation rCGG-mediated neurodegeneration.
Human molecular genetics
H Tan, A Qurashi, M Poidevin, DL Nelson, H Li, P Jin 01/01/2012 MicroRNA-277 modulates the neurodegeneration caused by Fragile X premutation rCGG repeats.
PLoS genetics
H Tan, M Poidevin, H Li, D Chen, P Jin 01/01/2012 Fragile X mental retardation protein and stem cells.
Results and problems in cell differentiation
A Qurashi, X Li, P Jin 01/01/2012 5-hmC-mediated epigenetic dynamics during postnatal neurodevelopment and aging.
Nature neuroscience
KE Szulwach, X Li, Y Li, CX Song, H Wu, Q Dai, H Irier, AK Upadhyay, M Gearing, AI Levey, A Vasanthakumar, LA Godley, Q Chang, X Cheng, C He, P Jin 10/30/2011 RNA-binding protein FXR2 regulates adult hippocampal neurogenesis by reducing Noggin expression.
Neuron
W Guo, L Zhang, DM Christopher, ZQ Teng, SR Fausett, C Liu, OL George, J Klingensmith, P Jin, X Zhao 06/09/2011 Integrating 5-hydroxymethylcytosine into the epigenomic landscape of human embryonic stem cells.
PLoS genetics
KE Szulwach, X Li, Y Li, CX Song, JW Han, S Kim, S Namburi, K Hermetz, JJ Kim, MK Rudd, YS Yoon, B Ren, C He, P Jin 06/01/2011 PLoS genetics
A Qurashi, W Li, JY Zhou, J Peng, P Jin 06/01/2011 Selective chemical labeling reveals the genome-wide distribution of 5-hydroxymethylcytosine.
Nature biotechnology
CX Song, KE Szulwach, Y Fu, Q Dai, C Yi, X Li, Y Li, CH Chen, W Zhang, X Jian, J Wang, L Zhang, TJ Looney, B Zhang, LA Godley, LM Hicks, BT Lahn, P Jin, C He 01/01/2011 Emergence of chemical biology approaches to the RNAi/miRNA pathway.
Chemistry & biology
Y Li, C He, P Jin 06/25/2010 MicroRNA miR-137 regulates neuronal maturation by targeting ubiquitin ligase mind bomb-1.
Stem cells (Dayton, Ohio)
RD Smrt, KE Szulwach, RL Pfeiffer, X Li, W Guo, M Pathania, ZQ Teng, Y Luo, J Peng, A Bordey, P Jin, X Zhao 06/01/2010 Roles of small regulatory RNAs in determining neuronal identity.
Nature reviews. Neuroscience
X Li, P Jin 05/01/2010 Cross talk between microRNA and epigenetic regulation in adult neurogenesis.
The Journal of cell biology
KE Szulwach, X Li, RD Smrt, Y Li, Y Luo, L Lin, NJ Santistevan, W Li, X Zhao, P Jin 04/05/2010 Small RNA-mediated gene regulation in neurodevelopmental disorders.
Current psychiatry reports
A Qurashi, P Jin 04/01/2010 RNA-mediated pathogenesis in fragile X-associated disorders.
Neuroscience letters
H Tan, H Li, P Jin 12/04/2009 Germline mutation of microRNA-125a is associated with breast cancer.
Journal of medical genetics
W Li, R Duan, F Kooy, SL Sherman, W Zhou, P Jin 05/01/2009 Small regulatory RNAs in neurodevelopmental disorders.
Human molecular genetics
S Chang, S Wen, D Chen, P Jin 04/15/2009 Noncoding RNAs in mental retardation.
Clinical genetics
KE Szulwach, P Jin, RS Alisch 03/01/2009 Macro role(s) of microRNAs in fragile X syndrome?
Neuromolecular medicine
X Li, P Jin 01/01/2009 The microRNA pathway and fragile X mental retardation protein.
Biochimica et biophysica acta
Y Li, L Lin, P Jin 11/01/2008 A small molecule enhances RNA interference and promotes microRNA processing.
Nature biotechnology
G Shan, Y Li, J Zhang, W Li, KE Szulwach, R Duan, MA Faghihi, AM Khalil, L Lu, Z Paroo, AW Chan, Z Shi, Q Liu, C Wahlestedt, C He, P Jin 08/01/2008 Identification of small molecules rescuing fragile X syndrome phenotypes in Drosophila.
Nature chemical biology
S Chang, SM Bray, Z Li, DC Zarnescu, C He, P Jin, ST Warren 04/01/2008 FXTAS: a bad RNA and a hope for a cure.
Expert opinion on biological therapy
G Shan, S Xu, P Jin 03/01/2008