Amita Manatunga, PhD

Research Program

Cancer Prevention and Control
Phone Number

404-727-1309
Email Address

amanatu@emory.edu

Biography

Amita Manatunga, PhD, is the Donna J. Brogan Professor in Biostatistics at Rollins School of Public Health, Emory University. Dr. Manatunga first joined the Emory University faculty in 1994. She works as the primary biostatistician at the NIH-funded Emory University General Clinical Research Center.

Dr. Manatunga is a member of the Cancer Prevention and Control Research Program at Winship Cancer Institute of Emory University.

Education

Dr. Manatunga obtained her PhD in Statistics and her MA also in Statistics from the Univeristy of Rochester in New York. She also received MSc in Statistics from Purdue University in Indiana.

Titles & Roles

Donna J. Brogan Professor in Biostatistics

Rollins School of Public Health, Emory University

Professional Memberships

Dr. Manatunga is a fellow of the American Statistical Association and a fellow of the American Association for the Advancement of Science. She has served on several committees of the ENAR, International Biometrics Society and over the years, she has also served on numerous NIH Study Sections.

Research

Dr. Manatunga's current research areas include analytical methods for environmental and reproductive health, multivariate survival analysis and predictive statistical models in renal imaging.

Publications

Title/Journal	Authors	Publication Date
Implementation of An Advance Care Planning Intervention in Dialysis Clinics. American journal of kidney diseases : the official journal of the National Kidney Foundation	MK Song, L Plantinga, M Metzger, N Noorani, J Lea, AV Kshirsagar, M Jhamb, EM Abdel-Rahman, M Laszlo, E Wu, J Englert, A Manatunga, S Benloukil, W Timmons, L Turberville-Trujillo, SE Ward	06/01/2025
Associations between obesity class and ambulatory blood pressure curves in African American women. Obesity (Silver Spring, Md.)	RJ Murden, ND Fields, ZT Martin, BB Risk, A Alonso, A Manatunga, CL Erving, R Moore, S Udaipuria, A Quyyumi, V Vaccarino, TT Lewis	03/01/2025
An integrative latent class model of heterogeneous data modalities for diagnosing kidney obstruction. Biostatistics (Oxford, England)	JH Jang, C Chang, AK Manatunga, AT Taylor, Q Long	07/01/2024
Effectiveness of an Advance Care Planning Intervention in Adults Receiving Dialysis and Their Families: A Cluster Randomized Clinical Trial. JAMA network open	MK Song, A Manatunga, L Plantinga, M Metzger, AV Kshirsagar, J Lea, EM Abdel-Rahman, M Jhamb, E Wu, J Englert, SE Ward	01/02/2024
Assessing intra- and inter-method agreement of functional data. Statistical methods in medical research	Y Yue, JH Jang, AK Manatunga	01/01/2024
Tensor response quantile regression with neuroimaging data. Biometrics	B Wei, L Peng, Y Guo, A Manatunga, J Stevens	09/01/2023
Computer assisted interpretation of Tc-99m mercaptoacetyltriglycine diuretic scintigraphy enhances resident performance. Nuclear medicine communications	AT Taylor, AKM Fazlur Rahman, RD Folks, V Moncayo, B Savir-Baruch, N Plaxton, A Polsani, RK Halkar, EV Dubovsky, EV Garcia, A Manatunga	06/01/2023
Diagnostic evaluation of pharmacokinetic features of functional markers. Journal of biopharmaceutical statistics	JH Jang, A Manatunga	05/04/2023
Racial Differences in Fatal Out-of-Hospital Coronary Heart Disease and the Role of Income in the Atherosclerosis Risk in Communities Cohort Study (1987 to 2017). The American journal of cardiology	D Islek, A Alonso, W Rosamond, CS Guild, KR Butler, MK Ali, A Manatunga, AI Naimi, V Vaccarino	05/01/2023
Differences in incident and recurrent myocardial infarction among White and Black individuals aged 35 to 84: Findings from the ARIC community surveillance study. American heart journal	D Islek, A Alonso, W Rosamond, A Kucharska-Newton, Y Mok, K Matsushita, S Koton, MJ Blaha, MK Ali, A Manatunga, V Vaccarino	11/01/2022
Racial Disparities in Hospitalization Among Patients Who Receive a Diagnosis of Acute Coronary Syndrome in the Emergency Department. Journal of the American Heart Association	D Islek, MK Ali, A Manatunga, A Alonso, V Vaccarino	10/04/2022
Special issue dedicated to David Oakes. Lifetime data analysis	JH Jeong, AK Manatunga	10/01/2022
A Bayesian multiple imputation approach to bivariate functional data with missing components. Statistics in medicine	JH Jang, AK Manatunga, C Chang, Q Long	09/30/2021
Gamma models for estimating the odds ratio for a skewed biomarker measured in pools and subject to errors. Biostatistics (Oxford, England)	DR Van Domelen, EM Mitchell, NJ Perkins, EF Schisterman, AK Manatunga, Y Huang, RH Lyles	04/10/2021
Nonparametric estimation of broad sense agreement between ordinal and censored continuous outcomes. Statistics in medicine	T Dai, Y Guo, L Peng, A Manatunga	06/30/2020
A New Functional Representation of Broad Sense Agreement. Statistics & probability letters	B Wei, T Dai, L Peng, Y Guo, A Manatunga	03/01/2020
A Bayesian Latent Class Model to Predict Kidney Obstruction in the Absence of Gold Standard. Journal of the American Statistical Association	C Chang, JH Jang, A Manatunga, AT Taylor, Q Long	01/01/2020
Assessing alignment between functional markers and ordinal outcomes based on broad sense agreement. Biometrics	JH Jang, L Peng, AK Manatunga	12/01/2019
A multidimensional analysis of the longitudinal effects of roux en y gastric bypass on fatigue: An association with visceral obesity. Physiology & behavior	N Gletsu-Miller, N Shevni, A Manatunga, E Lin, D Musselman	10/01/2019
Polybrominated Biphenyl Exposure and Menstrual Cycle Function. Epidemiology (Cambridge, Mass.)	PP Howards, ML Terrell, MH Jacobson, KC Taylor, JS Kesner, JW Meadows, JB Spencer, AK Manatunga, M Marcus	09/01/2019
A Smooth Nonparametric Approach to Determining Cut-Points of A Continuous Scale. Computational statistics & data analysis	Z Qiu, L Peng, A Manatunga, Y Guo	06/01/2019
The effects of roux en y gastric bypass surgery on neurobehavioral symptom domains associated with severe obesity. Physiology & behavior	D Musselman, N Shenvi, A Manatunga, AH Miller, E Lin, N Gletsu-Miller	05/15/2019
Overall indices for assessing agreement among multiple raters. Statistics in medicine	JH Jang, AK Manatunga, AT Taylor, Q Long	12/10/2018
Logistic regression with a continuous exposure measured in pools and subject to errors. Statistics in medicine	DR Van Domelen, EM Mitchell, NJ Perkins, EF Schisterman, AK Manatunga, Y Huang, RH Lyles	11/30/2018
iChoose Kidney for Treatment Options: Updated Models for Shared Decision Aid. Transplantation	JC Gander, M Basu, L McPherson, MD Garber, SO Pastan, A Manatunga, KJ Arriola, RE Patzer	09/01/2018
A local agreement pattern measure based on hazard functions for survival outcomes. Biometrics	T Dai, Y Guo, L Peng, AK Manatunga	03/01/2018
A latent class analysis of PTSD symptoms among inner city primary care patients. Journal of psychiatric research	AF Rahman, A Manatunga, Y Guo, L Peng, M Warnock, KJ Ressler, T Jovanovic	03/01/2018
SPIRIT trial: A phase III pragmatic trial of an advance care planning intervention in ESRD. Contemporary clinical trials	MK Song, ML Unruh, A Manatunga, LC Plantinga, J Lea, M Jhamb, AV Kshirsagar, SE Ward	01/01/2018
^99mTc-MAG₃: Image Wisely. Radiology	AT Taylor, RD Folks, AKMF Rahman, A Polsani, EV Dubovsky, R Halkar, A Manatunga	07/01/2017
A joint modeling approach for multivariate survival data with random length. Biometrics	S Liu, AK Manatunga, L Peng, M Marcus	06/01/2017
Impact of tamoxifen therapy on fertility in breast cancer survivors. Fertility and sterility	LM Shandley, JB Spencer, A Fothergill, AC Mertens, A Manatunga, E Paplomata, PP Howards	01/01/2017
Nonparametric Regression Method for Broad Sense Agreement. Journal of nonparametric statistics	AF Rahman, L Peng, A Manatunga, Y Guo	01/01/2017
A general approach to categorizing a continuous scale according to an ordinal outcome. Journal of statistical planning and inference	L Peng, A Manatunga, M Wang, Y Guo, AF Rahman	05/01/2016
Efficacy and Safety of Glutamine-supplemented Parenteral Nutrition in Surgical ICU Patients: An American Multicenter Randomized Controlled Trial. Annals of surgery	TR Ziegler, AK May, G Hebbar, KA Easley, DP Griffith, N Dave, BR Collier, GA Cotsonis, L Hao, T Leong, AK Manatunga, ES Rosenberg, DP Jones, GS Martin, GL Jensen, HC Sax, KA Kudsk, JR Galloway, HM Blumberg, ME Evans, PE Wischmeyer	04/01/2016
Quantile regression analysis of censored longitudinal data with irregular outcome-dependent follow-up. Biometrics	X Sun, L Peng, A Manatunga, M Marcus	03/01/2016
Menses resumption after cancer treatment-induced amenorrhea occurs early or not at all. Fertility and sterility	MH Jacobson, AC Mertens, JB Spencer, AK Manatunga, PP Howards	03/01/2016
Contribution of endothelium-derived hyperpolarizing factor to exercise-induced vasodilation in health and hypercholesterolemia. Vascular medicine (London, England)	MA Ozkor, SS Hayek, AM Rahman, JR Murrow, N Kavtaradze, J Lin, A Manatunga, AA Quyyumi	02/01/2015
A highly efficient design strategy for regression with outcome pooling. Statistics in medicine	EM Mitchell, RH Lyles, AK Manatunga, NJ Perkins, EF Schisterman	12/10/2014
Differences in vascular nitric oxide and endothelium-derived hyperpolarizing factor bioavailability in blacks and whites. Arteriosclerosis, thrombosis, and vascular biology	MA Ozkor, AM Rahman, JR Murrow, N Kavtaradze, J Lin, A Manatunga, S Hayek, AA Quyyumi	06/01/2014
Regression for skewed biomarker outcomes subject to pooling. Biometrics	EM Mitchell, RH Lyles, AK Manatunga, M Danaher, NJ Perkins, EF Schisterman	03/01/2014
Endothelium-derived hyperpolarizing factor mediates bradykinin-stimulated tissue plasminogen activator release in humans. Journal of vascular research	AM Rahman, JR Murrow, MA Ozkor, N Kavtaradze, J Lin, C De Staercke, WC Hooper, A Manatunga, S Hayek, AA Quyyumi	01/01/2014
New agreement measures based on survival processes. Biometrics	Y Guo, R Li, L Peng, AK Manatunga	12/01/2013
Reference values for renal size obtained from MAG3 scintigraphy. Clinical nuclear medicine	AT Taylor, N Shenvi, RD Folks, EV Garcia, BS Baruch, A Manatunga	01/01/2013
Neurobehavioral effects of interferon-α in patients with hepatitis-C: symptom dimensions and responsiveness to paroxetine. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology	MD McNutt, S Liu, A Manatunga, EB Royster, CL Raison, BJ Woolwine, MF Demetrashvili, AH Miller, DL Musselman	05/01/2012
Changes in heart rate variability of depressed patients after electroconvulsive therapy. Cardiovascular psychiatry and neurology	EB Royster, LM Trimble, G Cotsonis, B Schmotzer, A Manatunga, NN Rushing, G Pagnoni, SF Auyeung, AR Brown, J Schoenbeck, S Murthy, WM McDonald, DL Musselman	01/01/2012
Clustering Based on Periodicity in High-Throughput Time Course Data. Statistical analysis and data mining	AJ Blackstock, AK Manatunga, Y Park, DP Jones, T Yu	12/01/2011
Key variables for interpreting 99mTc-mercaptoacetyltriglycine diuretic scans: development and validation of a predictive model. AJR. American journal of roentgenology	J Bao, A Manatunga, JN Binongo, AT Taylor	08/01/2011
Computer-aided diagnosis of renal obstruction: utility of log-linear modeling versus standard ROC and kappa analysis. EJNMMI research	AK Manatunga, JN Binongo, AT Taylor	06/20/2011
Endothelium-derived hyperpolarizing factor determines resting and stimulated forearm vasodilator tone in health and in disease. Circulation	MA Ozkor, JR Murrow, AM Rahman, N Kavtaradze, J Lin, A Manatunga, AA Quyyumi	05/24/2011
A Framework for Assessing Broad Sense Agreement Between Ordinal and Continuous Measurements. Journal of the American Statistical Association	L Peng, R Li, Y Guo, A Manatunga	01/01/2011
A 7% decrease in the differential renal uptake of MAG3 implies a loss in renal function. Urology	A Taylor, A Manatunga, R Halkar, MM Issa, NV Shenvi	12/01/2010
Likelihood-based methods for estimating the association between a health outcome and left- or interval-censored longitudinal exposure data. Statistics in medicine	KA Wannemuehler, RH Lyles, AK Manatunga, ML Terrell, M Marcus	07/20/2010
High habitual dietary alpha-linolenic acid intake is associated with decreased plasma soluble interleukin-6 receptor concentrations in male twins. The American journal of clinical nutrition	J Dai, TR Ziegler, RM Bostick, AK Manatunga, DP Jones, J Goldberg, A Miller, G Vogt, PW Wilson, L Jones, L Shallenberger, V Vaccarino	07/01/2010
A note on assessing agreement for frailty models. Statistics & probability letters	Y Guo, AK Manatunga	04/01/2010
Menstrual cycle variability and the likelihood of achieving pregnancy. Reviews on environmental health	CM Small, AK Manatunga, M Klein, CE Dominguez, HS Feigelson, R McChesney, M Marcus	01/01/2010
Variability of phthalate monoester levels in daily first-morning urine from adult women: a pilot study. Reviews on environmental health	M Marcus, KY Christensen, A Manatunga, CB Rudra, JW Brock, CM Small	01/01/2010
Sequential multiple-assignment randomized trial design of neurobehavioral treatment for patients with metastatic malignant melanoma undergoing high-dose interferon-alpha therapy. Clinical trials (London, England)	SF Auyeung, Q Long, EB Royster, S Murthy, MD McNutt, D Lawson, A Miller, A Manatunga, DL Musselman	10/01/2009
Bone marrow mobilization with granulocyte macrophage colony-stimulating factor improves endothelial dysfunction and exercise capacity in patients with peripheral arterial disease. American heart journal	V Subramaniyam, EK Waller, JR Murrow, A Manatunga, S Lonial, K Kasirajan, D Sutcliffe, W Harris, WR Taylor, RW Alexander, AA Quyyumi	07/01/2009
Covariate-Adjusted Constrained Bayes Predictions of Random Intercepts and Slopes. Journal of modern applied statistical methods : JMASM	RH Lyles, RH Moore, AK Manatunga, KA Easley	05/01/2009
Measuring agreement of multivariate discrete survival times using a modified weighted kappa coefficient. Biometrics	Y Guo, AK Manatunga	03/01/2009
Association between adherence to the Mediterranean diet and oxidative stress. The American journal of clinical nutrition	J Dai, DP Jones, J Goldberg, TR Ziegler, RM Bostick, PW Wilson, AK Manatunga, L Shallenberger, L Jones, V Vaccarino	11/01/2008
A decay model for assessing polybrominated biphenyl exposure among women in the Michigan Long-Term PBB Study. Journal of exposure science & environmental epidemiology	ML Terrell, AK Manatunga, CM Small, LL Cameron, J Wirth, HM Blanck, RH Lyles, M Marcus	07/01/2008
Shattered Shangri-la: differences in depressive and anxiety symptoms in students born in Tibet compared to Tibetan students born in exile. Social psychiatry and psychiatric epidemiology	D Evans, DC Buxton, A Borisov, AK Manatunga, D Ngodup, CL Raison	06/01/2008
Platelet thromboxane A2 secretion in patients with major depression responsive to electroconvulsive therapy. Psychosomatic medicine	EC Bruce, Y Guo, KC Lawson, AK Manatunga, SF Auyeung, WM McDonald, N Rushing, AR Brown, N Gilles, M Emery, R Bonsall, J Porquez, Z Stowe, CB Nemeroff, DL Musselman	04/01/2008
Modeling survival data with informative cluster size. Statistics in medicine	JM Williamson, HY Kim, A Manatunga, DG Addiss	02/20/2008
Diagnostic performance of an expert system for interpretation of 99mTc MAG3 scans in suspected renal obstruction. Journal of nuclear medicine : official publication, Society of Nuclear Medicine	A Taylor, EV Garcia, JN Binongo, A Manatunga, R Halkar, RD Folks, E Dubovsky	02/01/2008
Decision support systems in diuresis renography. Seminars in nuclear medicine	A Taylor, A Manatunga, EV Garcia	01/01/2008

Awards

Dr. Manatunga received the Thomas Sellers Award from Rollins School of Public Health.