Carlos S. Moreno, PhD

Research Program

Cell and Molecular Biology
Phone Number

404-712-2809
Email Address

cmoreno@emory.edu

Biography

Carlos S. Moreno, PhD, is a professor in the Departments of Pathology and Laboratory Medicine, and Biomedical Informatics at the Emory University School of Medicine. Dr. Moreno serves as assistant director for education and training and is a member of the Cell and Molecular Biology Research Program at Winship Cancer Institute of Emory University.

Dr. Moreno specializes in cancer bioinformatics and systems biology, analysis of genome-wide expression profiles, transcriptional networks, ChIP-chip studies, biological pathway analysis, and computational analysis of transcription factor binding sites. Dr. Moreno is project leader for informatics for the Emory Molecular Interaction Center for Functional genomics (MicFG) as part of the Cancer Target Discovery and Development (CTD²) Network to analyze TCGA data for protein-protein interaction networks.

Education

Dr. Moreno earned his BS and MS from Massachusetts Institute of Technology in Cambridge, Massachusetts. He received his PhD from Emory University in Atlanta, Georgia.

Titles & Roles

Professor, Department of Pathology and Laboratory Medicine

Emory University School of Medicine
Professor, Department of Biomedical Informatics

Emory University School of Medicine
Assistant Director for Education and Training

Winship Cancer Institute of Emory University

Research

Dr. Moreno's main research interests are in translational cancer bioinformatics and systems biology, to identify diagnostic markers for more effective and personalized therapies, to identify new potential therapeutic targets, and to better understand the biology of tumor progression. His research has focused on the dissection of the perturbed transcriptional networks in prostate, brain, breast, and ovarian cancers using DNA microarrays and next generation sequencing. His lab has identified several genes that are strongly correlated with prostate cancer progression, including two developmental transcription factors, HOXC6 and SOX4. His lab is also developing mRNA and microRNA biomarkers of recurrence in prostate cancer. His lab analyzes genome-wide expression profiles, transcriptional networks, ChIP-chip and ChIP-seq studies, biological pathways and evolutionarily conserved transcription factor binding sites to dissect cancer-related transcriptional networks and identify new drug targets and biomarkers. They are heavily involved in analysis of data from The Cancer Genome Atlas project to identify potential drug targets as part of the Cancer Target Discovery and Development (CTD2) Network at NCI.

Publications

Title/Journal	Authors	Publication Date
Correction: Epidermal growth factor dampens pro-inflammatory gene expression induced by interferon-gamma in global transcriptome analysis of keratinocytes. BMC genomics	DC Gibbs, MR McCrary, CS Moreno, L Seldin, C Li, NAH Kamili, BP Pollack	03/24/2025
Deregulation of ABCG1 early in life contributes to prostate carcinogenesis in maternally malnourished offspring rats. Molecular and cellular endocrinology	AC Camargo, FB Constantino, SA Santos, KT Colombelli, LM Portela, MN Fioretto, LA Barata, GT Valente, CS Moreno, LA Justulin	01/15/2024
Integrated Genomic Analysis of Primary Prostate Tumor Foci and Corresponding Lymph Node Metastases Identifies Mutations and Pathways Associated with Metastasis. Cancers	CS Moreno, CL Winham, M Alemozaffar, ER Klein, IO Lawal, OA Abiodun-Ojo, D Patil, BG Barwick, Y Huang, DM Schuster, MG Sanda, AO Osunkoya	11/30/2023
Early-life origin of prostate cancer through deregulation of miR-206 networks in maternally malnourished offspring rats. Scientific reports	LMF Portela, FB Constantino, ACL Camargo, SAA Santos, KT Colombelli, MN Fioretto, LA Barata, EJR Silva, WR Scarano, SL Felisbino, CS Moreno, LA Justulin	10/31/2023
New insights into KLFs and SOXs in cancer pathogenesis, stemness, and therapy. Seminars in cancer biology	L Zeng, Y Zhu, CS Moreno, Y Wan	05/01/2023
High throughput, label-free isolation of circulating tumor cell clusters in meshed microwells. Nature communications	M Boya, T Ozkaya-Ahmadov, BE Swain, CH Chu, N Asmare, O Civelekoglu, R Liu, D Lee, S Tobia, S Biliya, LD McDonald, B Nazha, O Kucuk, MG Sanda, BB Benigno, CS Moreno, MA Bilen, JF McDonald, AF Sarioglu	06/13/2022
Systematic discovery of mutation-directed neo-protein-protein interactions in cancer. Cell	X Mo, Q Niu, AA Ivanov, YH Tsang, C Tang, C Shu, Q Li, K Qian, A Wahafu, SP Doyle, D Cicka, X Yang, D Fan, MA Reyna, LAD Cooper, CS Moreno, W Zhou, TK Owonikoko, S Lonial, FR Khuri, Y Du, SS Ramalingam, GB Mills, H Fu	05/26/2022
The Movember Global Action Plan 1 (GAP1): Unique Prostate Cancer Tissue Microarray Resource. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology	V Ouellet, A Erickson, K Wiley, C Morrissey, V Berge, CS Moreno, KA Tasken, D Trudel, LD True, MS Lewis, A Svindland, O Ertunc, ID Vidal, AO Osunkoya, T Jones, GS Bova, T Lamminen, AH Achtman, M Buzza, MM Kouspou, SA Bigler, X Zhou, SJ Freedland, AM Mes-Masson, IP Garraway, BJ Trock, P Taimen, F Saad, T Mirtti, BS Knudsen, AM De Marzo	04/01/2022
Transcriptomic landscape of male and female reproductive cancers: Similar pathways and molecular signatures predicting response to endocrine therapy. Molecular and cellular endocrinology	AC Camargo, B Remoli, LM Portela, MN Fioretto, LG Chuffa, CS Moreno, LA Justulin	09/15/2021
Pan-cancer analysis of pathway-based gene expression pattern at the individual level reveals biomarkers of clinical prognosis. Cell reports methods	K Su, Q Yu, R Shen, SY Sun, CS Moreno, X Li, ZS Qin	08/23/2021
Variation of microRNA expression in the human placenta driven by population identity and sex of the newborn. BMC genomics	S Guo, S Huang, X Jiang, H Hu, D Han, CS Moreno, GL Fairbrother, DA Hughes, M Stoneking, P Khaitovich	04/20/2021
Characterization of exosome release and extracellular vesicle-associated miRNAs for human bronchial epithelial cells irradiated with high charge and energy ions. Life sciences in space research	Z Li, KK Jella, L Jaafar, CS Moreno, WS Dynan	02/01/2021
SOX4: The unappreciated oncogene. Seminars in cancer biology	CS Moreno	12/01/2020
Correction to: Overexpression of SOX4 induces up-regulation of miR-126 and miR-195 in LNCaP prostate cancer cell line. Cytotechnology	NN Phan, CS Moreno, YH Lai	08/01/2020
Overexpression of SOX4 induces up-regulation of miR-126 and miR-195 in LNCaP prostate cancer cell line. Cytotechnology	NN Phan, CS Moreno, YH Lai	08/01/2020
Androgen attenuates the inactivating phospho-Ser-127 modification of yes-associated protein 1 (YAP1) and promotes YAP1 nuclear abundance and activity. The Journal of biological chemistry	B Cinar, MM Al-Mathkour, SA Khan, CS Moreno	06/19/2020
EZH2 has a non-catalytic and PRC2-independent role in stabilizing DDB2 to promote nucleotide excision repair. Oncogene	AE Koyen, MZ Madden, D Park, EV Minten, P Kapoor-Vazirani, E Werner, NT Pfister, R Haji-Seyed-Javadi, H Zhang, J Xu, N Deng, DM Duong, TJ Pecen, Z Frazier, ZD Nagel, JB Lazaro, KW Mouw, NT Seyfried, CS Moreno, TK Owonikoko, X Deng, DS Yu	06/01/2020
Genomic copy number variation correlates with survival outcomes in WHO grade IV glioma. Scientific reports	ZS Buchwald, S Tian, M Rossi, GH Smith, J Switchenko, JE Hauenstein, CS Moreno, RH Press, RS Prabhu, J Zhong, DF Saxe, SG Neill, JJ Olson, IR Crocker, WJ Curran, HG Shu	04/30/2020
The JNK inhibitor AS602801 Synergizes with Enzalutamide to Kill Prostate Cancer Cells In Vitro and In Vivo and Inhibit Androgen Receptor Expression. Translational oncology	Z Li, C Sun, S Tao, AO Osunkoya, RS Arnold, JA Petros, X Zu, CS Moreno	04/01/2020
Combined HER3-EGFR score in triple-negative breast cancer provides prognostic and predictive significance superior to individual biomarkers. Scientific reports	A Ogden, S Bhattarai, B Sahoo, NP Mongan, M Alsaleem, AR Green, M Aleskandarany, IO Ellis, S Pattni, XB Li, CS Moreno, U Krishnamurti, EA Janssen, K Jonsdottir, E Rakha, P Rida, R Aneja	02/20/2020
Phosphoinositide 3-Kinase Signaling Can Modulate MHC Class I and II Expression. Molecular cancer research : MCR	S Chandrasekaran, M Sasaki, CD Scharer, HT Kissick, DG Patterson, KR Magliocca, JT Seykora, B Sapkota, DA Gutman, LA Cooper, GB Lesinski, EK Waller, SN Thomas, SV Kotenko, JM Boss, CS Moreno, RA Swerlick, BP Pollack	12/01/2019
SOX4 regulates invasion of bladder cancer cells via repression of WNT5a. International journal of oncology	JD Moran, HH Kim, Z Li, CS Moreno	08/01/2019
Use of Everolimus and Trastuzumab in Addition to Endocrine Therapy in Hormone-Refractory Metastatic Breast Cancer. Clinical breast cancer	E Paplomata, A Zelnak, CA Santa-Maria, Y Liu, K Gogineni, X Li, CS Moreno, Z Chen, V Kaklamani, RM O'Regan	06/01/2019
Identification of the Transcription Factor Relationships Associated with Androgen Deprivation Therapy Response and Metastatic Progression in Prostate Cancer. Cancers	NV Sharma, KL Pellegrini, V Ouellet, FO Giuste, S Ramalingam, K Watanabe, E Adam-Granger, L Fossouo, S You, MR Freeman, P Vertino, K Conneely, AO Osunkoya, D Trudel, AM Mes-Masson, JA Petros, F Saad, CS Moreno	10/11/2018
Selective modification of fluciclovine (¹⁸F) transport in prostate carcinoma xenografts. Amino acids	FI Tade, WG Wiles, G Lu, B Bilir, O Akin-Akintayo, JS Lee, D Patil, W Yu, C Ormenisan Gherasim, B Fei, CS Moreno, AO Osunkoya, EJ Teoh, S Oka, H Okudaira, MM Goodman, DM Schuster	09/01/2018
The OncoPPi Portal: an integrative resource to explore and prioritize protein-protein interactions for cancer target discovery. Bioinformatics (Oxford, England)	AA Ivanov, B Revennaugh, L Rusnak, V Gonzalez-Pecchi, X Mo, MA Johns, Y Du, LAD Cooper, CS Moreno, FR Khuri, H Fu	04/01/2018
The E2F activators control multiple mitotic regulators and maintain genomic integrity through Sgo1 and BubR1. Oncotarget	M Lee, Y Rivera-Rivera, CS Moreno, HI Saavedra	09/29/2017
Effects of genistein supplementation on genome‑wide DNA methylation and gene expression in patients with localized prostate cancer. International journal of oncology	B Bilir, NV Sharma, J Lee, B Hammarstrom, A Svindland, O Kucuk, CS Moreno	07/01/2017
Evaluation of a 24-gene signature for prognosis of metastatic events and prostate cancer-specific mortality. BJU international	KL Pellegrini, MG Sanda, D Patil, Q Long, M Santiago-Jiménez, M Takhar, N Erho, K Yousefi, E Davicioni, EA Klein, RB Jenkins, RJ Karnes, CS Moreno	06/01/2017
Detection of prostate cancer-specific transcripts in extracellular vesicles isolated from post-DRE urine. The Prostate	KL Pellegrini, D Patil, KJS Douglas, G Lee, K Wehrmeyer, M Torlak, J Clark, CS Cooper, CS Moreno, MG Sanda	06/01/2017
Enriching gene expression profiles will help personalize prostate cancer management for African-Americans: A perspective. Urologic oncology	S Vijayakumar, JC Henegan, X Zhang, W Wang, WA Day, V Vijayakumar, CS Moreno, CR Gomez	06/01/2017
Corrigendum: The OncoPPi network of cancer-focused protein-protein interactions to inform biological insights and therapeutic strategies. Nature communications	Z Li, AA Ivanov, R Su, V Gonzalez-Pecchi, Q Qi, S Liu, P Webber, E McMillan, L Rusnak, C Pham, X Chen, X Mo, B Revennaugh, W Zhou, A Marcus, S Harati, X Chen, MA Johns, MA White, CS Moreno, LAD Cooper, Y Du, FR Khuri, H Fu	04/18/2017
AKT1, LKB1, and YAP1 Revealed as MYC Interactors with NanoLuc-Based Protein-Fragment Complementation Assay. Molecular pharmacology	X Mo, Q Qi, AA Ivanov, Q Niu, Y Luo, J Havel, R Goetze, S Bell, CS Moreno, LA Cooper, MA Johns, FR Khuri, Y Du, H Fu	04/01/2017
The OncoPPi network of cancer-focused protein-protein interactions to inform biological insights and therapeutic strategies. Nature communications	Z Li, AA Ivanov, R Su, V Gonzalez-Pecchi, Q Qi, S Liu, P Webber, E McMillan, L Rusnak, C Pham, X Chen, X Mo, B Revennaugh, W Zhou, A Marcus, S Harati, X Chen, MA Johns, MA White, C Moreno, LA Cooper, Y Du, FR Khuri, H Fu	02/16/2017
MEDICI: Mining Essentiality Data to Identify Critical Interactions for Cancer Drug Target Discovery and Development. PloS one	S Harati, LA Cooper, JD Moran, FO Giuste, Y Du, AA Ivanov, MA Johns, FR Khuri, H Fu, CS Moreno	01/01/2017
Cosmc is an X-linked inflammatory bowel disease risk gene that spatially regulates gut microbiota and contributes to sex-specific risk. Proceedings of the National Academy of Sciences of the United States of America	MR Kudelka, BH Hinrichs, T Darby, CS Moreno, H Nishio, CE Cutler, J Wang, H Wu, J Zeng, Y Wang, T Ju, SR Stowell, A Nusrat, RM Jones, AS Neish, RD Cummings	12/20/2016
MELK kinase holds promise as a new radiosensitizing target and biomarker in triple-negative breast cancer. Journal of thoracic disease	CS Moreno	10/01/2016
Gene integrated set profile analysis: a context-based approach for inferring biological endpoints. Nucleic acids research	J Kowalski, B Dwivedi, S Newman, JM Switchenko, R Pauly, DA Gutman, J Arora, K Gandhi, K Ainslie, G Doho, Z Qin, CS Moreno, MR Rossi, PM Vertino, S Lonial, L Bernal-Mizrachi, LH Boise	04/20/2016
SOX4 Is Essential for Prostate Tumorigenesis Initiated by PTEN Ablation. Cancer research	B Bilir, AO Osunkoya, WG Wiles, S Sannigrahi, V Lefebvre, D Metzger, DD Spyropoulos, WD Martin, CS Moreno	03/01/2016
Hierarchical Feature Selection Incorporating Known and Novel Biological Information: Identifying Genomic Features Related to Prostate Cancer Recurrence. Journal of the American Statistical Association	Y Zhao, M Chung, BA Johnson, CS Moreno, Q Long	01/01/2016
Claudin-based barrier differentiation in the colonic epithelial crypt niche involves Hopx/Klf4 and Tcf7l2/Hnf4-α cascades. Tissue barriers	LN Lili, AE Farkas, C Gerner-Smidt, CE Overgaard, CS Moreno, CA Parkos, CT Capaldo, A Nusrat	01/01/2016
RNA biomarkers to facilitate the identification of aggressive prostate cancer. Molecular aspects of medicine	KL Pellegrini, MG Sanda, CS Moreno	11/01/2015
Lycopene in the prevention of renal cell cancer in the TSC2 mutant Eker rat model. Archives of biochemistry and biophysics	K Sahin, B Cross, N Sahin, K Ciccone, S Suleiman, AO Osunkoya, V Master, W Harris, B Carthon, R Mohammad, B Bilir, K Wertz, CS Moreno, CL Walker, O Kucuk	04/15/2015
Evaluating intra- and inter-individual variation in the human placental transcriptome. Genome biology	DA Hughes, M Kircher, Z He, S Guo, GL Fairbrother, CS Moreno, P Khaitovich, M Stoneking	03/19/2015
Human Brat ortholog TRIM3 is a tumor suppressor that regulates asymmetric cell division in glioblastoma. Cancer research	G Chen, J Kong, C Tucker-Burden, M Anand, Y Rong, F Rahman, CS Moreno, EG Van Meir, CG Hadjipanayis, DJ Brat	08/15/2014
E2F activators signal and maintain centrosome amplification in breast cancer cells. Molecular and cellular biology	MY Lee, CS Moreno, HI Saavedra	07/01/2014
Global transcriptome analysis of formalin-fixed prostate cancer specimens identifies biomarkers of disease recurrence. Cancer research	Q Long, J Xu, AO Osunkoya, S Sannigrahi, BA Johnson, W Zhou, T Gillespie, JY Park, RK Nam, L Sugar, A Stanimirovic, AK Seth, JA Petros, CS Moreno	06/15/2014
Assessing needs and assets for building a regional network infrastructure to reduce cancer related health disparities. Evaluation and program planning	KJ Wells, DS Lima, CD Meade, T Muñoz-Antonia, I Scarinci, A McGuire, CK Gwede, WJ Pledger, E Partridge, J Lipscomb, R Matthews, J Matta, I Flores, R Weiner, T Turner, L Miele, TE Wiese, M Fouad, CS Moreno, M Lacey, DW Christie, EG Price-Haywood, GP Quinn, D Coppola, SO Sodeke, BL Green, MY Lichtveld	06/01/2014
Gene expression profiling of clear cell papillary renal cell carcinoma: comparison with clear cell renal cell carcinoma and papillary renal cell carcinoma. Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc	KE Fisher, Q Yin-Goen, D Alexis, JS Sirintrapun, W Harrison, R Benjamin Isett, MR Rossi, CS Moreno, AN Young, AO Osunkoya	02/01/2014
Integrated analysis of whole-genome paired-end and mate-pair sequencing data for identifying genomic structural variations in multiple myeloma. Cancer informatics	R Yang, L Chen, S Newman, K Gandhi, G Doho, CS Moreno, PM Vertino, L Bernal-Mizarchi, S Lonial, LH Boise, M Rossi, J Kowalski, ZS Qin	01/01/2014
Mutation of murine Sox4 untranslated regions results in partially penetrant perinatal lethality. In vivo (Athens, Greece)	WG Wiles, Z Mou, Y Du, AB Long, CD Scharer, B Bilir, DD Spyropoulos, NA Jenkins, NG Copeland, WD Martin, CS Moreno	01/01/2014
High-Performance Computational Analysis of Glioblastoma Pathology Images with Database Support Identifies Molecular and Survival Correlates. Proceedings. IEEE International Conference on Bioinformatics and Biomedicine	J Kong, F Wang, G Teodoro, L Cooper, CS Moreno, T Kurc, T Pan, J Saltz, D Brat	12/01/2013
Wnt signaling in triple negative breast cancer is associated with metastasis. BMC cancer	N Dey, BG Barwick, CS Moreno, M Ordanic-Kodani, Z Chen, G Oprea-Ilies, W Tang, C Catzavelos, KF Kerstann, GW Sledge, M Abramovitz, M Bouzyk, P De, BR Leyland-Jones	11/10/2013
Wnt signaling blockage inhibits cell proliferation and migration, and induces apoptosis in triple-negative breast cancer cells. Journal of translational medicine	B Bilir, O Kucuk, CS Moreno	11/04/2013
Tumor-infiltrating lymphocytes in glioblastoma are associated with specific genomic alterations and related to transcriptional class. Clinical cancer research : an official journal of the American Association for Cancer Research	WC Rutledge, J Kong, J Gao, DA Gutman, LA Cooper, C Appin, Y Park, L Scarpace, T Mikkelsen, ML Cohen, KD Aldape, RE McLendon, NL Lehman, CR Miller, MJ Schniederjan, CW Brennan, JH Saltz, CS Moreno, DJ Brat	09/15/2013
MR imaging predictors of molecular profile and survival: multi-institutional study of the TCGA glioblastoma data set. Radiology	DA Gutman, LA Cooper, SN Hwang, CA Holder, J Gao, TD Aurora, WD Dunn, L Scarpace, T Mikkelsen, R Jain, M Wintermark, M Jilwan, P Raghavan, E Huang, RJ Clifford, P Mongkolwat, V Kleper, J Freymann, J Kirby, PO Zinn, CS Moreno, C Jaffe, R Colen, DL Rubin, J Saltz, A Flanders, DJ Brat	05/01/2013
Computational identification of conserved transcription factor binding sites upstream of genes induced in rat brain by transient focal ischemic stroke. Brain research	JV Pulliam, Z Xu, GD Ford, C Liu, Y Li, KC Stovall, VS Cannon, T Tewolde, CS Moreno, BD Ford	02/07/2013
Characterization of primary prostate carcinoma by anti-1-amino-2-[(18)F] -fluorocyclobutane-1-carboxylic acid (anti-3-[(18)F] FACBC) uptake. American journal of nuclear medicine and molecular imaging	DM Schuster, PA Taleghani, PT Nieh, VA Master, R Amzat, B Savir-Baruch, RK Halkar, T Fox, AO Osunkoya, CS Moreno, JA Nye, W Yu, B Fei, Z Wang, Z Chen, MM Goodman	01/01/2013
Machine-based morphologic analysis of glioblastoma using whole-slide pathology images uncovers clinically relevant molecular correlates. PloS one	J Kong, LA Cooper, F Wang, J Gao, G Teodoro, L Scarpace, T Mikkelsen, MJ Schniederjan, CS Moreno, JH Saltz, DJ Brat	01/01/2013
The tumor microenvironment strongly impacts master transcriptional regulators and gene expression class of glioblastoma. The American journal of pathology	LA Cooper, DA Gutman, C Chisolm, C Appin, J Kong, Y Rong, T Kurc, EG Van Meir, JH Saltz, CS Moreno, DJ Brat	05/01/2012
Genistein cooperates with the histone deacetylase inhibitor vorinostat to induce cell death in prostate cancer cells. BMC cancer	CJ Phillip, CK Giardina, B Bilir, DJ Cutler, YH Lai, O Kucuk, CS Moreno	04/11/2012
Integrated morphologic analysis for the identification and characterization of disease subtypes. Journal of the American Medical Informatics Association : JAMIA	LA Cooper, J Kong, DA Gutman, F Wang, J Gao, C Appin, S Cholleti, T Pan, A Sharma, L Scarpace, T Mikkelsen, T Kurc, CS Moreno, DJ Brat, JH Saltz	01/01/2012
Integrative, multimodal analysis of glioblastoma using TCGA molecular data, pathology images, and clinical outcomes. IEEE transactions on bio-medical engineering	J Kong, LA Cooper, F Wang, DA Gutman, J Gao, C Chisolm, A Sharma, T Pan, EG Van Meir, TM Kurc, CS Moreno, JH Saltz, DJ Brat	12/01/2011
SOX4 interacts with plakoglobin in a Wnt3a-dependent manner in prostate cancer cells. BMC cell biology	YH Lai, J Cheng, D Cheng, ME Feasel, KD Beste, J Peng, A Nusrat, CS Moreno	11/19/2011
Heterogeneity of primary glioblastoma cells in the expression of caspase-8 and the response to TRAIL-induced apoptosis. Apoptosis : an international journal on programmed cell death	L Qi, AC Bellail, MR Rossi, Z Zhang, H Pang, S Hunter, C Cohen, CS Moreno, JJ Olson, S Li, C Hao	11/01/2011
Protein phosphatase 2a (PP2A) binds within the oligomerization domain of striatin and regulates the phosphorylation and activation of the mammalian Ste20-Like kinase Mst3. BMC biochemistry	J Gordon, J Hwang, KJ Carrier, CA Jones, QL Kern, CS Moreno, RH Karas, DC Pallas	10/10/2011
Risk Prediction for Prostate Cancer Recurrence Through Regularized Estimation with Simultaneous Adjustment for Nonlinear Clinical Effects. The annals of applied statistics	Q Long, M Chung, CS Moreno, BA Johnson	09/01/2011
Protein-coding and microRNA biomarkers of recurrence of prostate cancer following radical prostatectomy. The American journal of pathology	Q Long, BA Johnson, AO Osunkoya, YH Lai, W Zhou, M Abramovitz, M Xia, MB Bouzyk, RK Nam, L Sugar, A Stanimirovic, DJ Williams, BR Leyland-Jones, AK Seth, JA Petros, CS Moreno	07/01/2011
A COMPREHENSIVE FRAMEWORK FOR CLASSIFICATION OF NUCLEI IN DIGITAL MICROSCOPY IMAGING: AN APPLICATION TO DIFFUSE GLIOMAS. Proceedings. IEEE International Symposium on Biomedical Imaging	J Kong, L Cooper, F Wang, C Chisolm, C Moreno, T Kurc, P Widener, D Brat, J Saltz	03/30/2011
MORPHOLOGICAL SIGNATURES AND GENOMIC CORRELATES IN GLIOBLASTOMA. Proceedings. IEEE International Symposium on Biomedical Imaging	LA Cooper, J Kong, F Wang, T Kurc, CS Moreno, DJ Brat, JH Saltz	03/30/2011
In silico analysis of nuclei in glioblastoma using large-scale microscopy images improves prediction of treatment response. Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference	J Kong, L Cooper, C Moreno, F Wang, T Kurc, J Saltz, D Brat	01/01/2011
Identification of candidate genes for histiocytoid cardiomyopathy (HC) using whole genome expression analysis: analyzing material from the HC registry. Pediatric and developmental pathology : the official journal of the Society for Pediatric Pathology and the Paediatric Pathology Society	BM Shehata, M Bouzyk, SC Shulman, W Tang, CK Steelman, GK Davis, CS Moreno	01/01/2011
An integrative approach for in silico glioma research. IEEE transactions on bio-medical engineering	LA Cooper, J Kong, DA Gutman, F Wang, SR Cholleti, TC Pan, PM Widener, A Sharma, T Mikkelsen, AE Flanders, DL Rubin, EG Van Meir, TM Kurc, CS Moreno, DJ Brat, JH Saltz	10/01/2010
The proneural molecular signature is enriched in oligodendrogliomas and predicts improved survival among diffuse gliomas. PloS one	LA Cooper, DA Gutman, Q Long, BA Johnson, SR Cholleti, T Kurc, JH Saltz, DJ Brat, CS Moreno	09/03/2010
Prostate cancer genes associated with TMPRSS2-ERG gene fusion and prognostic of biochemical recurrence in multiple cohorts. British journal of cancer	BG Barwick, M Abramovitz, M Kodani, CS Moreno, R Nam, W Tang, M Bouzyk, A Seth, B Leyland-Jones	02/02/2010
The Sex-determining region Y-box 4 and homeobox C6 transcriptional networks in prostate cancer progression: crosstalk with the Wnt, Notch, and PI3K pathways. The American journal of pathology	CS Moreno	02/01/2010
Identification of a novel small molecule HIF-1alpha translation inhibitor. Clinical cancer research : an official journal of the American Association for Cancer Research	T Narita, S Yin, CF Gelin, CS Moreno, M Yepes, KC Nicolaou, EG Van Meir	10/01/2009
Genome-wide promoter analysis of the SOX4 transcriptional network in prostate cancer cells. Cancer research	CD Scharer, CD McCabe, M Ali-Seyed, MF Berger, ML Bulyk, CS Moreno	01/15/2009
Aurora kinase inhibitors synergize with paclitaxel to induce apoptosis in ovarian cancer cells. Journal of translational medicine	CD Scharer, N Laycock, AO Osunkoya, S Logani, JF McDonald, BB Benigno, CS Moreno	12/11/2008
Sox7 Is an independent checkpoint for beta-catenin function in prostate and colon epithelial cells. Molecular cancer research : MCR	L Guo, D Zhong, S Lau, X Liu, XY Dong, X Sun, VW Yang, PM Vertino, CS Moreno, V Varma, JT Dong, W Zhou	09/01/2008
Genome-wide analysis of the homeobox C6 transcriptional network in prostate cancer. Cancer research	CD McCabe, DD Spyropoulos, D Martin, CS Moreno	03/15/2008
Optimization of RNA extraction from FFPE tissues for expression profiling in the DASL assay. BioTechniques	M Abramovitz, M Ordanic-Kodani, Y Wang, Z Li, C Catzavelos, M Bouzyk, GW Sledge, CS Moreno, B Leyland-Jones	03/01/2008
Genomic promoter analysis predicts functional transcription factor binding. Advances in bioinformatics	JS Rao, S Karanam, CD McCabe, CS Moreno	01/01/2008
Molecular pathogenesis of human prolactinomas identified by gene expression profiling, RT-qPCR, and proteomic analyses. Pituitary	CO Evans, CS Moreno, X Zhan, MT McCabe, PM Vertino, DM Desiderio, NM Oyesiku	01/01/2008
Evidence that p53-mediated cell-cycle-arrest inhibits chemotherapeutic treatment of ovarian carcinomas. PloS one	CS Moreno, L Matyunina, EB Dickerson, N Schubert, NJ Bowen, S Logani, BB Benigno, JF McDonald	05/16/2007
Expression microarray analysis of brain tumors: what have we learned so far. Frontiers in bioscience : a journal and virtual library	SB Hunter, CS Moreno	08/01/2002