Maureen Powers, PhD

Research Program

Cell and Molecular Biology
Phone Number

404-727-8859
Email Address

mpowers@emory.edu

Biography

Maureen A. Powers, PhD, is an associate professor in the Department of Cell Biology at Emory University School of Medicine. Dr. Powers is a member of the Cell and Molecular Biology Research Program at Winship Cancer Institute.

Education

Dr. Powers received her PhD from the University of California.

Titles & Roles

Associate Professor, Department of Cell Biology

Emory University School of Medicine

Research

The research interests of Dr. Powers' laboratory center on the function of the Nuclear Pore Complex (NPC) and its component proteins, the nucleoporins (Nups). The NPC is responsible for movement of proteins and RNAs between nucleus and the cytoplasm, a fundamental activity of the eukaryotic cell. This process is mediated by the NPC along with an extensive series of cargo receptors, the alpha and beta karyopherin families. The long term goal is to understand how NPC function is regulated and tightly integrated with other cellular processes including nuclear organization, cell division and transcription.

Publications

Title/Journal	Authors	Publication Date
Residency Program Directors' Views on Research Conducted During Medical School: A National Survey. Academic medicine : journal of the Association of American Medical Colleges	RK Wolfson, PC Fairchild, I Bahner, DM Baxa, DR Birnbaum, SI Chaudhry, KC Chretien, DB DeFranco, AZ Deptola, LEW LaConte, JJ Lin, L Petch Lee, MA Powers, IJ Ropson, SM Sankaran, KE Sawarynski, SM Sozio	10/01/2023
TDP-43 pathology disrupts nuclear pore complexes and nucleocytoplasmic transport in ALS/FTD. Nature neuroscience	CC Chou, Y Zhang, ME Umoh, SW Vaughan, I Lorenzini, F Liu, M Sayegh, PG Donlin-Asp, YH Chen, DM Duong, NT Seyfried, MA Powers, T Kukar, CM Hales, M Gearing, NJ Cairns, KB Boylan, DW Dickson, R Rademakers, YJ Zhang, L Petrucelli, R Sattler, DC Zarnescu, JD Glass, W Rossoll	02/01/2018
STRUCTURAL BIOLOGY. Locking down the core of the pore. Science (New York, N.Y.)	KS Ullman, MA Powers	10/02/2015
Intranuclear dynamics of the Nup107-160 complex. Molecular biology of the cell	S Morchoisne-Bolhy, MC Geoffroy, IB Bouhlel, A Alves, N Audugé, X Baudin, K Van Bortle, MA Powers, V Doye	06/15/2015
Activation of diverse signalling pathways by oncogenic PIK3CA mutations. Nature communications	X Wu, S Renuse, NA Sahasrabuddhe, MS Zahari, R Chaerkady, MS Kim, RS Nirujogi, M Mohseni, P Kumar, R Raju, J Zhong, J Yang, J Neiswinger, JS Jeong, R Newman, MA Powers, BL Somani, E Gabrielson, S Sukumar, V Stearns, J Qian, H Zhu, B Vogelstein, BH Park, A Pandey	09/23/2014
The SUMO proteases SENP1 and SENP2 play a critical role in nucleoporin homeostasis and nuclear pore complex function. Molecular biology of the cell	KH Chow, S Elgort, M Dasso, MA Powers, KS Ullman	01/01/2014
In vivo analysis of human nucleoporin repeat domain interactions. Molecular biology of the cell	S Xu, MA Powers	04/01/2013
Nuclear pore component Nup98 is a potential tumor suppressor and regulates posttranscriptional expression of select p53 target genes. Molecular cell	S Singer, R Zhao, AM Barsotti, A Ouwehand, M Fazollahi, E Coutavas, K Breuhahn, O Neumann, T Longerich, T Pusterla, MA Powers, KM Giles, PJ Leedman, J Hess, D Grunwald, HJ Bussemaker, RH Singer, P Schirmacher, C Prives	12/14/2012
Nuclear transport: beginning to gel? Current biology : CB	MA Powers, DJ Forbes	12/04/2012
Domain topology of nucleoporin Nup98 within the nuclear pore complex. Journal of structural biology	G Chatel, SH Desai, AL Mattheyses, MA Powers, B Fahrenkrog	01/01/2012
Nup98 regulates bipolar spindle assembly through association with microtubules and opposition of MCAK. Molecular biology of the cell	MK Cross, MA Powers	03/01/2011
Nup98-homeodomain fusions interact with endogenous Nup98 during interphase and localize to kinetochores and chromosome arms during mitosis. Molecular biology of the cell	S Xu, MA Powers	05/01/2010
Nuclear pore proteins and cancer. Seminars in cell & developmental biology	S Xu, MA Powers	07/01/2009
Learning about cancer from frogs: analysis of mitotic spindles in Xenopus egg extracts. Disease models & mechanisms	MK Cross, MA Powers	01/01/2009
In vitro nuclear assembly using fractionated Xenopus egg extracts. Journal of visualized experiments : JoVE	M Cross, M Powers	09/02/2008
Preparation and fractionation of Xenopus laevis egg extracts. Journal of visualized experiments : JoVE	MK Cross, M Powers	08/27/2008
Obtaining eggs from Xenopus laevis females. Journal of visualized experiments : JoVE	MK Cross, M Powers	08/20/2008