Cheng-Kui Qu, MD, PhD
-
Research Program
-
Phone Number
-
Email Address

Cheng-Kui Qu, MD, PhD is a professor in the Department of Pediatrics at Emory University School of Medicine. Dr. Qu is a member of the Cell and Molecular Biology Research Program at Winship Cancer Institute of Emory University.
Dr. Qu received his Medical Degree from Anhui Medical University in China. He then earned his PhD in Experimental Hematology from the Chinese Academy of Medical Sciences in China. He completed his fellowship in the Department of Biochemistry and Molecular Biology, Walther Oncology Center, Indiana University School of Medicine in Indianapolis, Indiana.
Grant Number | Title |
---|---|
1R01CA275964-01 | Targeting leukemic stem cells in acute myeloid leukemia |
1R21CA282579-01 | Eradicating leukemic stem cells in juvenile myelomonocytic leukemia |
2R01HL130995-05A1 | Germline mutations of PTPN11 (SHP2) in the stem cell microenvironment |
5R01CA275964-02 | Targeting leukemic stem cells in acute myeloid leukemia |
5R01CA275964-03 | Targeting leukemic stem cells in acute myeloid leukemia |
5R01HL130995-06 | Germline mutations of PTPN11 (SHP2) in the stem cell microenvironment |
5R01HL130995-07 | Germline mutations of PTPN11 (SHP2) in the stem cell microenvironment |
5R01HL130995-08 | Germline mutations of PTPN11 (SHP2) in the stem cell microenvironment |
5R21CA282579-02 | Eradicating leukemic stem cells in juvenile myelomonocytic leukemia |
Dr. Qu has been published in numerous scientific peer-reviewed journals. He serves on the editorial board of Blood Advances.
Title/Journal | Authors | Publication Date |
---|---|---|
Nature biomedical engineering |
M Wu, H Yang, S Liu, L Jiang, T Liang, Y Wang, M Zhu, X Song, H Liu, J Shen, S Wang, X Zhu, CK Qu, L Cheng, H Jiang, F Ni | 12/23/2024 |
Research square |
H Zheng, P Zhao, Z Tan, WM Yu, J Werner, E Stieglitz, C Porter, S Chandrakasan, D Wechsler, S Mendez-Ferrer, CK Qu | 08/02/2024 |
Nature communications |
S Chouhan, D Sridaran, C Weimholt, J Luo, T Li, MC Hodgson, LN Santos, S Le Sommer, B Fang, JM Koomen, M Seeliger, CK Qu, A Yart, MI Kontaridis, K Mahajan, NP Mahajan | 07/04/2024 |
Mitochondrial metabolic flexibility is critical for CD8+ T cell antitumor immunity. Science advances |
C Chen, H Zheng, EM Horwitz, S Ando, K Araki, P Zhao, Z Li, ML Ford, R Ahmed, CK Qu | 12/08/2023 |
AMPK activator-treated human cardiac spheres enhance maturation and enable pathological modeling. Stem cell research & therapy |
D Li, LC Armand, F Sun, H Hwang, D Wolfson, A Rampoldi, R Liu, P Forghani, X Hu, WM Yu, CK Qu, DP Jones, R Wu, HC Cho, JT Maxwell, C Xu | 11/08/2023 |
eLife |
H Zheng, Q Li, S Li, Z Li, M Brotto, D Weiss, D Prosdocimo, C Xu, A Reddy, M Puchowicz, X Zhao, MN Weitzmann, MK Jain, CK Qu | 09/06/2023 |
Scientific reports |
Y Yan, C Chen, Z Li, J Zhang, N Park, CK Qu | 12/17/2022 |
Cellular signals converge at the NOX2-SHP-2 axis to induce reductive carboxylation in cancer cells. Cell chemical biology |
R Zhang, D Chen, H Fan, R Wu, J Tu, FQ Zhang, M Wang, H Zheng, CK Qu, SE Elf, B Faubert, YY He, MB Bissonnette, X Gao, RJ DeBerardinis, J Chen | 07/21/2022 |
Blood advances |
Y Yan, L Dong, C Chen, KD Bunting, Q Li, E Stieglitz, ML Loh, CK Qu | 01/11/2022 |
Methylation of dual-specificity phosphatase 4 controls cell differentiation. Cell reports |
H Su, M Jiang, C Senevirathne, S Aluri, T Zhang, H Guo, J Xavier-Ferrucio, S Jin, NT Tran, SM Liu, CW Sun, Y Zhu, Q Zhao, Y Chen, L Cable, Y Shen, J Liu, CK Qu, X Han, CA Klug, R Bhatia, Y Chen, SD Nimer, YG Zheng, C Iancu-Rubin, J Jin, H Deng, DS Krause, J Xiang, A Verma, M Luo, X Zhao | 07/27/2021 |
Decreased cell stiffness enhances leukemia development and progression. Leukemia |
L Hu, F Ni, X Wang, ME Fay, KM Young, WA Lam, TA Sulchek, CK Qu | 09/01/2020 |
Germline mutations: many roles in leukemogenesis. Current opinion in hematology |
KZ Chen, R Kazi, CC Porter, CK Qu | 07/01/2020 |
Journal of molecular and cellular cardiology |
C Gentillon, D Li, M Duan, WM Yu, MK Preininger, R Jha, A Rampoldi, A Saraf, GC Gibson, CK Qu, LA Brown, C Xu | 07/01/2019 |
Ptpn21 Controls Hematopoietic Stem Cell Homeostasis and Biomechanics. Cell stem cell |
F Ni, WM Yu, X Wang, ME Fay, KM Young, Y Qiu, WA Lam, TA Sulchek, T Cheng, DT Scadden, CK Qu | 04/04/2019 |
Nature metabolism |
F Ni, WM Yu, Z Li, DK Graham, L Jin, S Kang, MR Rossi, S Li, HE Broxmeyer, CK Qu | 03/01/2019 |
Journal of medicinal chemistry |
X Wu, G Xu, X Li, W Xu, Q Li, W Liu, KA Kirby, ML Loh, J Li, SG Sarafianos, CK Qu | 02/14/2019 |
The Journal of pathology |
J Gagné-Sansfacon, A Langlois, MJ Langlois, G Coulombe, S Tremblay, V Vaillancourt-Lavigueur, CK Qu, A Menendez, N Rivard | 01/01/2019 |
Pathobiological Pseudohypoxia as a Putative Mechanism Underlying Myelodysplastic Syndromes. Cancer discovery |
Y Hayashi, Y Zhang, A Yokota, X Yan, J Liu, K Choi, B Li, G Sashida, Y Peng, Z Xu, R Huang, L Zhang, GM Freudiger, J Wang, Y Dong, Y Zhou, J Wang, L Wu, J Bu, A Chen, X Zhao, X Sun, K Chetal, A Olsson, M Watanabe, LE Romick-Rosendale, H Harada, LY Shih, W Tse, JP Bridges, MA Caligiuri, T Huang, Y Zheng, DP Witte, QF Wang, CK Qu, N Salomonis, HL Grimes, SD Nimer, Z Xiao, G Huang | 11/01/2018 |
Germline mutations in the bone marrow microenvironment and dysregulated hematopoiesis. Experimental hematology |
LH Miller, CK Qu, M Pauly | 10/01/2018 |
Science advances |
H Zheng, WM Yu, J Shen, S Kang, D Hambardzumyan, JY Li, Y Shen, AM Kenney, J Chen, CK Qu | 10/01/2018 |
MAST1 Drives Cisplatin Resistance in Human Cancers by Rewiring cRaf-Independent MEK Activation. Cancer cell |
L Jin, J Chun, C Pan, D Li, R Lin, GN Alesi, X Wang, HB Kang, L Song, D Wang, G Zhang, J Fan, TJ Boggon, L Zhou, J Kowalski, CK Qu, CE Steuer, GZ Chen, NF Saba, LH Boise, TK Owonikoko, FR Khuri, KR Magliocca, DM Shin, S Lonial, S Kang | 08/13/2018 |
Hematopoietic-restricted Ptpn11E76K reveals indolent MPN progression in mice. Oncotarget |
SP Tarnawsky, WM Yu, CK Qu, RJ Chan, MC Yoder | 04/24/2018 |
Science signaling |
H Zheng, WM Yu, RR Waclaw, MI Kontaridis, BG Neel, CK Qu | 03/20/2018 |
Molecular cell |
L Jin, J Chun, C Pan, A Kumar, G Zhang, Y Ha, D Li, GN Alesi, Y Kang, L Zhou, WM Yu, KR Magliocca, FR Khuri, CK Qu, C Metallo, TK Owonikoko, S Kang | 01/04/2018 |
Leukemia |
HA O'Leary, M Capitano, S Cooper, C Mantel, HS Boswell, R Kapur, B Ramdas, R Chan, L Deng, CK Qu, HE Broxmeyer | 11/01/2017 |
Blood |
L Dong, H Zheng, CK Qu | 09/21/2017 |
Leukemia |
W Liu, WM Yu, J Zhang, RJ Chan, ML Loh, Z Zhang, KD Bunting, CK Qu | 06/01/2017 |
Leukaemogenic effects of Ptpn11 activating mutations in the stem cell microenvironment. Nature |
L Dong, WM Yu, H Zheng, ML Loh, ST Bunting, M Pauly, G Huang, M Zhou, HE Broxmeyer, DT Scadden, CK Qu | 11/10/2016 |
Leukemia research |
HS Sabnis, HL Bradley, S Tripathi, WM Yu, W Tse, CK Qu, KD Bunting | 11/01/2016 |
Discovery of Dual Inhibitors of MDM2 and XIAP for Cancer Treatment. Cancer cell |
L Gu, H Zhang, T Liu, S Zhou, Y Du, J Xiong, S Yi, CK Qu, H Fu, M Zhou | 10/10/2016 |
Oncotarget |
J Gagné-Sansfaçon, G Coulombe, MJ Langlois, A Langlois, M Paquet, J Carrier, GS Feng, CK Qu, N Rivard | 10/04/2016 |
A metabolic stress-induced cell cycle checkpoint in stem cells. Cell cycle (Georgetown, Tex.) |
F Ni, CK Qu | 10/01/2016 |
Microenvironmental regulation of hematopoietic stem cells and its implications in leukemogenesis. Current opinion in hematology |
M Seshadri, CK Qu | 07/01/2016 |
Proceedings of the National Academy of Sciences of the United States of America |
X Liu, H Zheng, X Li, S Wang, HJ Meyerson, W Yang, BG Neel, CK Qu | 01/26/2016 |
Maintenance of mouse hematopoietic stem cells ex vivo by reprogramming cellular metabolism. Blood |
X Liu, H Zheng, WM Yu, TM Cooper, KD Bunting, CK Qu | 03/05/2015 |
Flow cytometric analysis of signaling and apoptosis in hematopoietic stem cells. Methods in molecular biology (Clifton, N.J.) |
L Dong, CK Qu | 01/01/2014 |
The hematopoietic stem cell landscape. Methods in molecular biology (Clifton, N.J.) |
KD Bunting, CK Qu | 01/01/2014 |
Molecular targets for the treatment of juvenile myelomonocytic leukemia. Advances in hematology |
X Liu, H Sabnis, KD Bunting, CK Qu | 01/01/2012 |
Molecular-targeted therapies for hematologic malignancies. Advances in hematology |
KD Bunting, CK Qu, MH Tomasson | 01/01/2012 |
Blood |
D Xu, S Wang, WM Yu, G Chan, T Araki, KD Bunting, BG Neel, CK Qu | 11/04/2010 |
Dr. Qu has earned the following awards and honors: