Khalid Salaita, PhD

Research Program

Cell and Molecular Biology
Phone Number

404-727-7522
Email Address

k.salaita@emory.edu

Biography

Khalid Salaita, PhD, is the Samuel Chandler Dobbs Professor of Chemistry, associate professor and director of graduate studies in the Department of Chemistry at Emory University. He is also program faculty in the Wallace H. Coulter Department of Biomedical Engineering at Emory University and Georgia Institute of Technology.

Dr. Salaita is a member of the Cell and Molecular Biology Research Program at Winship Cancer Institute of Emory University in Atlanta, Georgia.

Education

Dr. Salaita earned his PhD in Chemistry from Northwestern University in 2006. After obtaining his PhD, Dr. Salaita completed a postdoctoral fellowship in the Department of Chemistry at the University of California, Berkeley.

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Titles & Roles

Associate Professor and Director for Graduate Studies, Department of Chemistry

Emory University
Samuel Candler Dobbs Professor of Chemistry

Emory University
Program Faculty, Department of Biomedical Engineering

Emory University and Georgia Institute of Technology

Research

Dr. Salaita's lab is interested in studying the role of mechanical forces in cell biology and tumor development. To address this goal, they develop new technologies to image mechanical forces generated by cells using molecules that fluoresce upon experiencing mechanical tension. They also develop nanoparticle actuators that can apply mechanical forces to cells, allowing them to understand how forces influence biology and disease progression.

Grants

View Grants

Grant Number	Title
1R01AI172452-01A1	Mechano-ID for tagging immune cells
1RM1GM145394-01A1	Center on Probes for Molecular Mechanotechnology
3RM1GM145394-01A1S1	Equipment Supplement: Cell sorting flow cytometry to support the BTDD
5R01AI172452-02	Mechano-ID for tagging immune cells
5R01AI172452-03	Mechano-ID for tagging immune cells
5RM1GM145394-02	Center on Probes for Molecular Mechanotechnology

Publications

Title/Journal	Authors	Publication Date
Digital and Tunable Genetically Encoded Tension Sensors Based on Engineered Coiled-Coils. Angewandte Chemie (International ed. in English)	S Liu, J Liu, A Foote, H Ogasawara, S Al Abdullatif, VS Batista, K Salaita	02/17/2025
On-Demand Photoactivation of DNA-Based Motor Motion. ACS nano	S Piranej, H Ogasawara, L Zhang, K Jackson, A Bazrafshan, K Salaita	02/11/2025
Quantifying T cell receptor mechanics at membrane junctions using DNA origami tension sensors. Nature nanotechnology	Y Hu, J Rogers, Y Duan, A Velusamy, S Narum, S Al Abdullatif, K Salaita	11/01/2024
Mechanical force regulates ligand binding and function of PD-1. Nature communications	K Li, P Cardenas-Lizana, J Lyu, AV Kellner, M Li, P Cong, VE Watson, Z Yuan, E Ahn, L Doudy, Z Li, K Salaita, R Ahmed, C Zhu	09/27/2024
Measuring Integrin Force Loading Rates Using a Two-Step DNA Tension Sensor. Journal of the American Chemical Society	JD Combs, AK Foote, H Ogasawara, A Velusamy, SA Rashid, JN Mancuso, K Salaita	08/21/2024
Mechanical control of antigen detection and discrimination by T and B cell receptors. Biophysical journal	J Rogers, AT Bajur, K Salaita, KM Spillane	08/06/2024
Rolosense: Mechanical Detection of SARS-CoV-2 Using a DNA-Based Motor. ACS central science	S Piranej, L Zhang, A Bazrafshan, M Marin, GB Melikian, K Salaita	07/24/2024
"Turbo-Charged" DNA Motors with Optimized Sequence Enable Single-Molecule Nucleic Acid Sensing. Angewandte Chemie (International ed. in English)	L Zhang, S Piranej, A Namazi, S Narum, K Salaita	03/22/2024
Force-Induced Site-Specific Enzymatic Cleavage Probes Reveal That Serial Mechanical Engagement Boosts T Cell Activation. Journal of the American Chemical Society	J Rogers, R Ma, A Foote, Y Hu, K Salaita	03/20/2024
Measuring integrin force loading rates using a two-step DNA tension sensor. bioRxiv : the preprint server for biology	JD Combs, AK Foote, H Ogasawara, A Velusamy, SA Rashid, JN Mancuso, K Salaita	03/15/2024
Molecular Compressive Force Sensor for Mapping Forces at the Cell-Substrate Interface. Journal of the American Chemical Society	S Al Abdullatif, S Narum, Y Hu, J Rogers, R Fitzgerald, K Salaita	03/13/2024
An Endosomal Escape Trojan Horse Platform to Improve Cytosolic Delivery of Nucleic Acids. ACS nano	S Narum, B Deal, H Ogasawara, JN Mancuso, J Zhang, K Salaita	02/27/2024
Cbl-b mitigates the responsiveness of naive CD8⁺ T cells that experience extensive tonic T cell receptor signaling. Science signaling	J Eggert, WM Zinzow-Kramer, Y Hu, EM Kolawole, YL Tsai, A Weiss, BD Evavold, K Salaita, CD Scharer, BB Au-Yeung	02/06/2024
The T-cell niche tunes immune function through modulation of the cytoskeleton and TCR-antigen forces. bioRxiv : the preprint server for biology	AV Kellner, R Hunter, P Do, J Eggert, M Jaffe, DK Geitgey, M Lee, JAG Hamilton, AJ Ross, RS Ank, RL Bender, R Ma, CC Porter, EC Dreaden, BB Au-Yeung, KA Haynes, CJ Henry, K Salaita	02/02/2024
Heteromultivalency enables enhanced detection of nucleic acid mutations. Nature chemistry	BR Deal, R Ma, S Narum, H Ogasawara, Y Duan, JT Kindt, K Salaita	02/01/2024
Simulated microgravity improves maturation of cardiomyocytes derived from human induced pluripotent stem cells. Scientific reports	P Forghani, A Rashid, LC Armand, D Wolfson, R Liu, HC Cho, JT Maxwell, H Jo, K Salaita, C Xu	01/26/2024
DNA mechanocapsules for programmable piconewton responsive drug delivery. Nature communications	A Velusamy, R Sharma, SA Rashid, H Ogasawara, K Salaita	01/24/2024
Author Correction: Mechanically active integrins target lytic secretion at the immune synapse to facilitate cellular cytotoxicity. Nature communications	MS Wang, Y Hu, EE Sanchez, X Xie, NH Roy, M de Jesus, BY Winer, EA Zale, W Jin, C Sachar, JH Lee, Y Hong, M Kim, LC Kam, K Salaita, M Huse	12/18/2023
Force-Triggered Self-Destructive Hydrogels. Advanced materials (Deerfield Beach, Fla.)	T Rajasooriya, H Ogasawara, Y Dong, JN Mancuso, K Salaita	12/01/2023
Polarized focal adhesion kinase activity within a focal adhesion during cell migration. Nature chemical biology	X Li, JD Combs, K Salaita, X Shu	12/01/2023
Nanodiscoidal Nucleic Acids for Gene Regulation. ACS chemical biology	R Sharma, S Narum, S Liu, Y Dong, KI Baek, H Jo, K Salaita	11/17/2023
Detection of cellular traction forces via the force-triggered Cas12a-mediated catalytic cleavage of a fluorogenic reporter strand. Nature biomedical engineering	Y Duan, F Szlam, Y Hu, W Chen, R Li, Y Ke, R Sniecinski, K Salaita	11/01/2023
Molecular mechanocytometry using tension-activated cell tagging. Nature methods	R Ma, SA Rashid, A Velusamy, BR Deal, W Chen, B Petrich, R Li, K Salaita	11/01/2023
Optomechanically Actuated Hydrogel Platform for Cell Stimulation with Spatial and Temporal Resolution. ACS biomaterials science & engineering	AN Ramey-Ward, Y Dong, J Yang, H Ogasawara, EC Bremer-Sai, O Brazhkina, C Franck, M Davis, K Salaita	09/11/2023
Mechanical force regulates ligand binding and function of PD-1. bioRxiv : the preprint server for biology	K Li, P Cardenas-Lizana, AV Kellner, Z Yuan, E Ahn, J Lyu, Z Li, K Salaita, R Ahmed, C Zhu	08/15/2023
Force-induced site-specific enzymatic cleavage probes reveal that serial mechanical engagement boosts T cell activation. bioRxiv : the preprint server for biology	J Rogers, R Ma, Y Hu, K Salaita	08/08/2023
DNA Nanotechnology for Investigating Mechanical Signaling in the Immune System. Angewandte Chemie (International ed. in English)	Y Hu, Y Duan, K Salaita	07/24/2023
All-Covalent Nuclease-Resistant and Hydrogel-Tethered DNA Hairpin Probes Map pN Cell Traction Forces. ACS applied materials & interfaces	SA Rashid, Y Dong, H Ogasawara, M Vierengel, ME Essien, K Salaita	07/19/2023
DNA Origami Tension Sensors (DOTS) to study T cell receptor mechanics at membrane junctions. bioRxiv : the preprint server for biology	Y Hu, Y Duan, A Velusamy, S Narum, J Rogers, K Salaita	07/12/2023
Rolosense: Mechanical detection of SARS-CoV-2 using a DNA-based motor. bioRxiv : the preprint server for biology	S Piranej, L Zhang, A Bazrafshan, M Marin, GB Melikyan, K Salaita	02/28/2023
RTK-integrin interactions universally modulate αVβ3 integrin-mediated cell adhesion. Biophysical journal	TC Rao, MD Patel, RR Beggs, R Ma, K Salaita, AL Mattheyses	02/10/2023
Accumulation of TCR signaling from self-antigens in naive CD8 T cells mitigates early responsiveness. bioRxiv : the preprint server for biology	J Eggert, WM Zinzow-Kramer, Y Hu, YL Tsai, A Weiss, K Salaita, CD Scharer, BB Au-Yeung	01/28/2023
Adhesive Dynamics Simulations of Highly Polyvalent DNA Motors. The journal of physical chemistry. B	AT Blanchard, S Piranej, V Pan, K Salaita	10/06/2022
Mechanically active integrins target lytic secretion at the immune synapse to facilitate cellular cytotoxicity. Nature communications	MS Wang, Y Hu, EE Sanchez, X Xie, NH Roy, M de Jesus, BY Winer, EA Zale, W Jin, C Sachar, JH Lee, Y Hong, M Kim, LC Kam, K Salaita, M Huse	06/09/2022
Chemical-to-mechanical molecular computation using DNA-based motors with onboard logic. Nature nanotechnology	S Piranej, A Bazrafshan, K Salaita	05/01/2022
DNA Tension Probes Show that Cardiomyocyte Maturation Is Sensitive to the Piconewton Traction Forces Transmitted by Integrins. ACS nano	SA Rashid, AT Blanchard, JD Combs, N Fernandez, Y Dong, HC Cho, K Salaita	04/26/2022
Imaging vesicle formation dynamics supports the flexible model of clathrin-mediated endocytosis. Nature communications	TJ Nawara, YD Williams, TC Rao, Y Hu, E Sztul, K Salaita, AL Mattheyses	04/01/2022
ST6Gal-I-mediated sialylation of the epidermal growth factor receptor modulates cell mechanics and enhances invasion. The Journal of biological chemistry	TC Rao, RR Beggs, KE Ankenbauer, J Hwang, VP Ma, K Salaita, SL Bellis, AL Mattheyses	04/01/2022
The magnitude of LFA-1/ICAM-1 forces fine-tune TCR-triggered T cell activation. Science advances	VP Ma, Y Hu, AV Kellner, JM Brockman, A Velusamy, AT Blanchard, BD Evavold, R Alon, K Salaita	02/25/2022
Gene Regulation Using Nanodiscs Modified with HIF-1-α Antisense Oligonucleotides. Bioconjugate chemistry	R Sharma, Y Dong, Y Hu, VP Ma, K Salaita	02/16/2022
Carfilzomib Treatment Causes Molecular and Functional Alterations of Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes. Journal of the American Heart Association	P Forghani, A Rashid, F Sun, R Liu, D Li, MR Lee, H Hwang, JT Maxwell, A Mandawat, R Wu, K Salaita, C Xu	12/21/2021
Supramolecular DNA Photonic Hydrogels for On-Demand Control of Coloration with High Spatial and Temporal Resolution. Nano letters	Y Dong, JD Combs, C Cao, ER Weeks, A Bazrafshan, SA Rashid, K Salaita	12/08/2021
Smart Nucleic Acids as Future Therapeutics. Trends in biotechnology	J Zhang, K Salaita	12/01/2021
Massively Parallelized Molecular Force Manipulation with On-Demand Thermal and Optical Control. Journal of the American Chemical Society	H Su, JM Brockman, Y Duan, N Sen, H Chhabra, A Bazrafshan, AT Blanchard, T Meyer, B Andrews, JPK Doye, Y Ke, RB Dyer, K Salaita	11/24/2021
Conditional Antisense Oligonucleotides Triggered by miRNA. ACS chemical biology	J Zhang, R Sharma, K Ryu, P Shen, K Salaita, H Jo	11/19/2021
Programmable Mechanically Active Hydrogel-Based Materials. Advanced materials (Deerfield Beach, Fla.)	Y Dong, AN Ramey-Ward, K Salaita	11/01/2021
Author Correction: Turn-key mapping of cell receptor force orientation and magnitude using a commercial structured illumination microscope. Nature communications	A Blanchard, JD Combs, JM Brockman, AV Kellner, R Glazier, H Su, RL Bender, AS Bazrafshan, W Chen, ME Quach, R Li, AL Mattheyses, K Salaita	09/16/2021
Mechanically Triggered Hybridization Chain Reaction. Angewandte Chemie (International ed. in English)	Y Duan, R Glazier, A Bazrafshan, Y Hu, SA Rashid, BG Petrich, Y Ke, K Salaita	09/01/2021
DNA-Based Microparticle Tension Sensors (μTS) for Measuring Cell Mechanics in Non-planar Geometries and for High-Throughput Quantification. Angewandte Chemie (International ed. in English)	Y Hu, VP Ma, R Ma, W Chen, Y Duan, R Glazier, BG Petrich, R Li, K Salaita	08/09/2021
Turn-key mapping of cell receptor force orientation and magnitude using a commercial structured illumination microscope. Nature communications	A Blanchard, JD Combs, JM Brockman, AV Kellner, R Glazier, H Su, RL Bender, AS Bazrafshan, W Chen, ME Quach, R Li, AL Mattheyses, K Salaita	08/03/2021
DNA Gold Nanoparticle Motors Demonstrate Processive Motion with Bursts of Speed Up to 50 nm Per Second. ACS nano	A Bazrafshan, ME Kyriazi, BA Holt, W Deng, S Piranej, H Su, Y Hu, AH El-Sagheer, T Brown, GA Kwong, AG Kanaras, K Salaita	05/25/2021
DNA Tension Probes to Map the Transient Piconewton Receptor Forces by Immune Cells. Journal of visualized experiments : JoVE	R Ma, AV Kellner, Y Hu, BR Deal, AT Blanchard, K Salaita	03/20/2021
Multivalent molecular tension probes as anisotropic mechanosensors: concept and simulation. Physical biology	AT Blanchard, K Salaita	03/15/2021
Spectroscopic Analysis of a Library of DNA Tension Probes for Mapping Cellular Forces at Fluid Interfaces. ACS applied materials & interfaces	R Glazier, P Shinde, H Ogasawara, K Salaita	01/20/2021
An Outside-In Switch in Integrin Signaling Caused by Chemical and Mechanical Signals in Reactive Astrocytes. Frontiers in cell and developmental biology	LA Pérez, A Rashid, JD Combs, P Schneider, A Rodríguez, K Salaita, L Leyton	01/01/2021
Shape-Shifting Peptide Nanomaterials: Surface Asymmetry Enables pH-Dependent Formation and Interconversion of Collagen Tubes and Sheets. Journal of the American Chemical Society	AD Merg, G Touponse, EV Genderen, TB Blum, X Zuo, A Bazrafshan, HMH Siaw, A McCanna, R Brian Dyer, K Salaita, JP Abrahams, VP Conticello	11/25/2020
Live-cell super-resolved PAINT imaging of piconewton cellular traction forces. Nature methods	JM Brockman, H Su, AT Blanchard, Y Duan, T Meyer, ME Quach, R Glazier, A Bazrafshan, RL Bender, AV Kellner, H Ogasawara, R Ma, F Schueder, BG Petrich, R Jungmann, R Li, AL Mattheyses, Y Ke, K Salaita	10/01/2020
Super-Resolution Fluorescence Imaging Reveals That Serine Incorporator Protein 5 Inhibits Human Immunodeficiency Virus Fusion by Disrupting Envelope Glycoprotein Clusters. ACS nano	YC Chen, C Sood, M Marin, J Aaron, E Gratton, K Salaita, GB Melikyan	09/22/2020
Conditional Deoxyribozyme-Nanoparticle Conjugates for miRNA-Triggered Gene Regulation. ACS applied materials & interfaces	J Zhang, R Ma, A Blanchard, J Petree, H Jo, K Salaita	08/26/2020
Mechanical Stimulation of Adhesion Receptors Using Light-Responsive Nanoparticle Actuators Enhances Myogenesis. ACS applied materials & interfaces	AN Ramey-Ward, H Su, K Salaita	08/12/2020
Optical Control of Cytokine Signaling via Bioinspired, Polymer-Induced Latency. Biomacromolecules	LA Perdue, P Do, C David, A Chyong, AV Kellner, A Ruggieri, HR Kim, K Salaita, GB Lesinski, CC Porter, EC Dreaden	07/13/2020
EGFR activation attenuates the mechanical threshold for integrin tension and focal adhesion formation. Journal of cell science	TC Rao, VP Ma, A Blanchard, TM Urner, S Grandhi, K Salaita, AL Mattheyses	07/10/2020
Tunable DNA Origami Motors Translocate Ballistically Over μm Distances at nm/s Speeds. Angewandte Chemie (International ed. in English)	A Bazrafshan, TA Meyer, H Su, JM Brockman, AT Blanchard, S Piranej, Y Duan, Y Ke, K Salaita	06/08/2020
Engineering DNA-Functionalized Nanostructures to Bind Nucleic Acid Targets Heteromultivalently with Enhanced Avidity. Journal of the American Chemical Society	BR Deal, R Ma, VP Ma, H Su, JT Kindt, K Salaita	05/27/2020
Forces during cellular uptake of viruses and nanoparticles at the ventral side. Nature communications	T Wiegand, M Fratini, F Frey, K Yserentant, Y Liu, E Weber, K Galior, J Ohmes, F Braun, DP Herten, S Boulant, US Schwarz, K Salaita, EA Cavalcanti-Adam, JP Spatz	01/02/2020
Seeded Heteroepitaxial Growth of Crystallizable Collagen Triple Helices: Engineering Multifunctional Two-Dimensional Core-Shell Nanostructures. Journal of the American Chemical Society	AD Merg, E van Genderen, A Bazrafshan, H Su, X Zuo, G Touponse, TB Blum, K Salaita, JP Abrahams, VP Conticello	12/26/2019
DNA mechanotechnology reveals that integrin receptors apply pN forces in podosomes on fluid substrates. Nature communications	R Glazier, JM Brockman, E Bartle, AL Mattheyses, O Destaing, K Salaita	10/18/2019
Highly Polyvalent DNA Motors Generate 100+ pN of Force via Autochemophoresis. Nano letters	AT Blanchard, AS Bazrafshan, J Yi, JT Eisman, KM Yehl, T Bian, A Mugler, K Salaita	10/09/2019
Chameleon-Inspired Strain-Accommodating Smart Skin. ACS nano	Y Dong, A Bazrafshan, A Pokutta, F Sulejmani, W Sun, JD Combs, KC Clarke, K Salaita	09/24/2019
2D Crystal Engineering of Nanosheets Assembled from Helical Peptide Building Blocks. Angewandte Chemie (International ed. in English)	AD Merg, G Touponse, E van Genderen, X Zuo, A Bazrafshan, T Blum, S Hughes, K Salaita, JP Abrahams, VP Conticello	09/16/2019
Emerging uses of DNA mechanical devices. Science (New York, N.Y.)	AT Blanchard, K Salaita	09/13/2019
DNA probes that store mechanical information reveal transient piconewton forces applied by T cells. Proceedings of the National Academy of Sciences of the United States of America	R Ma, AV Kellner, VP Ma, H Su, BR Deal, JM Brockman, K Salaita	08/20/2019
Macrophages exposed to HIV viral protein disrupt lung epithelial cell integrity and mitochondrial bioenergetics via exosomal microRNA shuttling. Cell death & disease	Z Yuan, JR Petree, FE Lee, X Fan, K Salaita, DM Guidot, RT Sadikot	08/02/2019
DNA Nanotechnology as an Emerging Tool to Study Mechanotransduction in Living Systems. Small (Weinheim an der Bergstrasse, Germany)	VP Ma, K Salaita	06/01/2019
Mechanical Proofreading: A General Mechanism to Enhance the Fidelity of Information Transfer Between Cells. Frontiers in physics	JM Brockman, K Salaita	02/01/2019
Localized Nanoscale Heating Leads to Ultrafast Hydrogel Volume-Phase Transition. ACS nano	J Zhao, H Su, GE Vansuch, Z Liu, K Salaita, RB Dyer	01/22/2019
A TCR mechanotransduction signaling loop induces negative selection in the thymus. Nature immunology	J Hong, C Ge, P Jothikumar, Z Yuan, B Liu, K Bai, K Li, W Rittase, M Shinzawa, Y Zhang, A Palin, P Love, X Yu, K Salaita, BD Evavold, A Singer, C Zhu	12/01/2018
Location, Location, Location: EphB4:Ephrin-B2 Signaling Depends on Its Spatial Arrangement. Biophysical journal	R Glazier, K Salaita	09/04/2018
Programmable Multivalent DNA-Origami Tension Probes for Reporting Cellular Traction Forces. Nano letters	PK Dutta, Y Zhang, AT Blanchard, C Ge, M Rushdi, K Weiss, C Zhu, Y Ke, K Salaita	08/08/2018
A brighter force gauge for cells. eLife	VP Ma, K Salaita	07/19/2018
Molecular Tension Probes to Investigate the Mechanopharmacology of Single Cells: A Step toward Personalized Mechanomedicine. Advanced healthcare materials	K Galior, VP Ma, Y Liu, H Su, N Baker, RA Panettieri, C Wongtrakool, K Salaita	07/01/2018
Light-Responsive Polymer Particles as Force Clamps for the Mechanical Unfolding of Target Molecules. Nano letters	H Su, Z Liu, Y Liu, VP Ma, A Blanchard, J Zhao, K Galior, RB Dyer, K Salaita	04/11/2018
Mapping the 3D orientation of piconewton integrin traction forces. Nature methods	JM Brockman, AT Blanchard, V Pui-Yan, WD Derricotte, Y Zhang, ME Fay, WA Lam, FA Evangelista, AL Mattheyses, K Salaita	02/01/2018
Site-Selective RNA Splicing Nanozyme: DNAzyme and RtcB Conjugates on a Gold Nanoparticle. ACS chemical biology	JR Petree, K Yehl, K Galior, R Glazier, B Deal, K Salaita	01/19/2018
Platelet integrins exhibit anisotropic mechanosensing and harness piconewton forces to mediate platelet aggregation. Proceedings of the National Academy of Sciences of the United States of America	Y Zhang, Y Qiu, AT Blanchard, Y Chang, JM Brockman, VP Ma, WA Lam, K Salaita	01/09/2018
Molecular Tension Probes for Imaging Forces at the Cell Surface. Accounts of chemical research	Y Liu, K Galior, VP Ma, K Salaita	12/19/2017
Supported lipid bilayer platforms to probe cell mechanobiology. Biochimica et biophysica acta. Biomembranes	R Glazier, K Salaita	09/01/2017
Image-guided genomics of phenotypically heterogeneous populations reveals vascular signalling during symbiotic collective cancer invasion. Nature communications	J Konen, E Summerbell, B Dwivedi, K Galior, Y Hou, L Rusnak, A Chen, J Saltz, W Zhou, LH Boise, P Vertino, L Cooper, K Salaita, J Kowalski, AI Marcus	05/12/2017
Ratiometric Tension Probes for Mapping Receptor Forces and Clustering at Intermembrane Junctions. Nano letters	VP Ma, Y Liu, L Blanchfield, H Su, BD Evavold, K Salaita	07/13/2016
DNA-based nanoparticle tension sensors reveal that T-cell receptors transmit defined pN forces to their antigens for enhanced fidelity. Proceedings of the National Academy of Sciences of the United States of America	Y Liu, L Blanchfield, VP Ma, R Andargachew, K Galior, Z Liu, B Evavold, K Salaita	05/17/2016
Mechanically Induced Catalytic Amplification Reaction for Readout of Receptor-Mediated Cellular Forces. Angewandte Chemie (International ed. in English)	VP Ma, Y Liu, K Yehl, K Galior, Y Zhang, K Salaita	04/25/2016
A General Approach for Generating Fluorescent Probes to Visualize Piconewton Forces at the Cell Surface. Journal of the American Chemical Society	Y Chang, Z Liu, Y Zhang, K Galior, J Yang, K Salaita	03/09/2016
Knockdown of TNF-α by DNAzyme gold nanoparticles as an anti-inflammatory therapy for myocardial infarction. Biomaterials	I Somasuntharam, K Yehl, SL Carroll, JT Maxwell, MD Martinez, PL Che, ME Brown, K Salaita, ME Davis	03/01/2016
Nanoscale optomechanical actuators for controlling mechanotransduction in living cells. Nature methods	Z Liu, Y Liu, Y Chang, HR Seyf, A Henry, AL Mattheyses, K Yehl, Y Zhang, Z Huang, K Salaita	02/01/2016
High-speed DNA-based rolling motors powered by RNase H. Nature nanotechnology	K Yehl, A Mugler, S Vivek, Y Liu, Y Zhang, M Fan, ER Weeks, K Salaita	02/01/2016
Titin-Based Nanoparticle Tension Sensors Map High-Magnitude Integrin Forces within Focal Adhesions. Nano letters	K Galior, Y Liu, K Yehl, S Vivek, K Salaita	01/13/2016
Real-time fluorescence imaging with 20 nm axial resolution. Nature communications	DR Stabley, T Oh, SM Simon, AL Mattheyses, K Salaita	09/22/2015
Lighting Up the Force: Investigating Mechanisms of Mechanotransduction Using Fluorescent Tension Probes. Molecular and cellular biology	C Jurchenko, KS Salaita	08/01/2015
DNA-based digital tension probes reveal integrin forces during early cell adhesion. Nature communications	Y Zhang, C Ge, C Zhu, K Salaita	10/24/2014
Nanoparticle tension probes patterned at the nanoscale: impact of integrin clustering on force transmission. Nano letters	Y Liu, R Medda, Z Liu, K Galior, K Yehl, JP Spatz, EA Cavalcanti-Adam, K Salaita	10/08/2014
The modulation of cardiac progenitor cell function by hydrogel-dependent Notch1 activation. Biomaterials	AV Boopathy, PL Che, I Somasuntharam, VF Fiore, EB Cabigas, K Ban, ME Brown, Y Narui, TH Barker, YS Yoon, K Salaita, AJ García, ME Davis	09/01/2014
Integrin-generated forces lead to streptavidin-biotin unbinding in cellular adhesions. Biophysical journal	C Jurchenko, Y Chang, Y Narui, Y Zhang, KS Salaita	04/01/2014
Structurally defined nanoscale sheets from self-assembly of collagen-mimetic peptides. Journal of the American Chemical Society	T Jiang, C Xu, Y Liu, Z Liu, JS Wall, X Zuo, T Lian, K Salaita, C Ni, D Pochan, VP Conticello	03/19/2014
Quantum dots encapsulated within phospholipid membranes: phase-dependent structure, photostability, and site-selective functionalization. Journal of the American Chemical Society	W Zheng, Y Liu, A West, EE Schuler, K Yehl, RB Dyer, JT Kindt, K Salaita	02/05/2014
Membrane tethered delta activates notch and reveals a role for spatio-mechanical regulation of the signaling pathway. Biophysical journal	Y Narui, K Salaita	12/17/2013
Tension sensing nanoparticles for mechano-imaging at the living/nonliving interface. Journal of the American Chemical Society	Y Liu, K Yehl, Y Narui, K Salaita	04/10/2013
Manipulating the lateral diffusion of surface-anchored EGF demonstrates that receptor clustering modulates phosphorylation levels. Integrative biology : quantitative biosciences from nano to macro	D Stabley, S Retterer, S Marshall, K Salaita	04/01/2013
Catalytic deoxyribozyme-modified nanoparticles for RNAi-independent gene regulation. ACS nano	K Yehl, JP Joshi, BL Greene, RB Dyer, R Nahta, K Salaita	10/23/2012
Visualizing mechanical tension across membrane receptors with a fluorescent sensor. Nature methods	DR Stabley, C Jurchenko, SS Marshall, KS Salaita	10/30/2011
L-Ala-γ-D-Glu-meso-diaminopimelic acid (DAP) interacts directly with leucine-rich region domain of nucleotide-binding oligomerization domain 1, increasing phosphorylation activity of receptor-interacting serine/threonine-protein kinase 2 and its interaction with nucleotide-binding oligomerization domain 1. The Journal of biological chemistry	H Laroui, Y Yan, Y Narui, SA Ingersoll, S Ayyadurai, MA Charania, F Zhou, B Wang, K Salaita, SV Sitaraman, D Merlin	09/02/2011
Nanomedicine in GI. American journal of physiology. Gastrointestinal and liver physiology	H Laroui, DS Wilson, G Dalmasso, K Salaita, N Murthy, SV Sitaraman, D Merlin	03/01/2011
Roles of the cytoskeleton in regulating EphA2 signals. Communicative & integrative biology	K Salaita, JT Groves	09/01/2010

Awards

Dr. Salaita has earned the following awards and honors:

Camille Dreyfus Teacher-Scholar Award, 2014
NSF Early CAREER Award, 2014
Alfred P. Sloan Research Fellow, 2013
Cancer Research Award, Georgia Cancer Coalition, 2010