Nicolas T. Seyfried, PhD

Research Program

Cell and Molecular Biology
Phone Number

404-712-9783
Email Address

nseyfri@emory.edu

Biography

Nicholas Seyfried, PhD, is a professor in the Department of Biochemistry and Neurology at Emory University School of Medicine and is a member of the Center for Neurodegenerative Diseases. As scientific director of the Emory Integrated Proteomics Core, he coordinates efforts to address the needs of investigators needing protein analytical services by cutting edge mass spectrometry.

Education

Dr. Seyfried earned his PhD in Biochemistry from the University of Oxford. He completed a postdoctoral fellowship at Emory University School of Medicine and held a postdoctoral research position in the Complex Carbohydrate Research Center at the University of Georgia.

Titles & Roles

Professor, Department of Biochemistry

Emory University School of Medicine
Scientific Director

Emory Integrated Proteomics Core

Professional Memberships

Dr. Seyfried holds memberships with American Society for Mass Spectrometry, Society for Neuroscience and American Society for Neurochemistry.

Research

Dr. Seyfried's research is focused on the use of quantitative proteomics to identify and characterize disease-specific proteins and their post-translational modifications (PTMs) in neurodegeneration.

Grants

View Grants

Grant Number	Title
2R01AG061800-06	Identifying therapeutic targets that confer synaptic resilience to Alzheimer's disease

Publications

Title/Journal	Authors	Publication Date
Astrocyte induction of disease-associated microglia is suppressed by acute exposure to fAD neurons in human iPSC triple cultures. Cell reports	AM Lish, N Ashour, RV Pearse, PC Galle, GA Orme, SE Heuer, CR Benoit, KD Alexander, EFL Grogan, G Terzioglu, A Scarpa, AM Stern, N Seyfried, V Menon, TL Young-Pearse	06/03/2025
Contributions of Genetic Variation in Astrocytes to Cell and Molecular Mechanisms of Risk and Resilience to Late-Onset Alzheimer's Disease. Glia	H Lee, RV Pearse, AM Lish, C Pan, ZM Augur, G Terzioglu, P Gaur, M Liao, M Fujita, ES Tio, DM Duong, D Felsky, NT Seyfried, V Menon, DA Bennett, PL De Jager, TL Young-Pearse	06/01/2025
Unraveling sex differences in Alzheimer's disease and related endophenotypes with brain proteomes. Alzheimer's & dementia : the journal of the Alzheimer's Association	Z Mei, J Liu, DA Bennett, N Seyfried, AP Wingo, TS Wingo	05/01/2025
CLU alleviates Alzheimer's disease-relevant processes by modulating astrocyte reactivity and microglia-dependent synaptic density. Neuron	AM Lish, EFL Grogan, CR Benoit, RV Pearse, SE Heuer, T Luquez, GA Orme, PC Galle, G Milinkeviciute, KN Green, KD Alexander, SB Fancher, AM Stern, M Fujita, DA Bennett, NT Seyfried, PL De Jager, V Menon, TL Young-Pearse	04/22/2025
ALS plasma biomarkers reveal neurofilament and pTau correlate with disease onset and progression. Annals of clinical and translational neurology	EV Thomas, C Han, WJ Kim, S Asress, Y Li, JA Taylor, M Gearing, CN Fournier, ZT McEachin, NT Seyfried, JD Glass	04/01/2025
Mapping medically relevant RNA isoform diversity in the aged human frontal cortex with deep long-read RNA-seq. Nature biotechnology	B Aguzzoli Heberle, JA Brandon, ML Page, KA Nations, KI Dikobe, BJ White, LA Gordon, GA Fox, ME Wadsworth, PH Doyle, BA Williams, EJ Fox, A Shantaraman, M Ryten, S Goodwin, E Ghiban, R Wappel, S Mavruk-Eskipehlivan, JB Miller, NT Seyfried, PT Nelson, JD Fryer, MTW Ebbert	04/01/2025
Translating the Post-Mortem Brain Multi-Omics Molecular Taxonomy of Alzheimer's Dementia to Living Humans. bioRxiv : the preprint server for biology	Y Iturria-Medina, VN Poole, AR Zammit, L Yu, S Tasaki, JH Hong, KP Lopes, C Batalha, AR Ridwan, RA Vialle, L Sanchez-Rodriguez, MR Geddes, P Abadir, E Ortlund, P De Jager, V Menon, MS Beeri, AS Buchman, Y Levin, D Morgenstern, JA Schneider, RK Daouk, T Wyss-Coray, NT Seyfried, K Arfanakis, P Rosa-Neto, Y Wang, DA Bennett	03/24/2025
Brain 5-hydroxymethylcytosine alterations are associated with Alzheimer's disease neuropathology. Nature communications	J Zhao, T Gu, C Gao, G Miao, H Palma-Gudiel, L Yu, J Yang, Y Wang, Y Li, J Lim, R Li, B Yao, H Wu, JA Schneider, N Seyfried, F Grodstein, PL De Jager, P Jin, DA Bennett	03/22/2025
Proteomic Subtyping of Alzheimer's Disease CSF links Blood-Brain Barrier Dysfunction to Reduced levels of Tau and Synaptic Biomarkers. bioRxiv : the preprint server for biology	MC Bangs, J Gadhavi, EK Carter, L Ping, DM Duong, EB Dammer, F Wu, A Shantaraman, EJ Fox, ECB Johnson, JJ Lah, AI Levey, NT Seyfried	03/15/2025
Longitudinal multi-omics in alpha-synuclein Drosophila model discriminates disease- from age-associated pathologies in Parkinson's disease. NPJ Parkinson's disease	J Moore, T Wu, J Dhindsa, O El Fadel, A Le, A Perez, B Amoh, A Tarkunde, KF Zhu, M Avalos, EB Dammer, DM Duong, NT Seyfried, JM Shulman, I Al-Ramahi, J Botas	03/11/2025
Structural variants linked to Alzheimer's disease and other common age-related clinical and neuropathologic traits. Genome medicine	RA Vialle, K de Paiva Lopes, Y Li, B Ng, JA Schneider, AS Buchman, Y Wang, JM Farfel, LL Barnes, AP Wingo, TS Wingo, NT Seyfried, PL De Jager, C Gaiteri, S Tasaki, DA Bennett	03/04/2025
Plasma Biomarkers for Cerebral Amyloid Angiopathy and Implications for Amyloid-Related Imaging Abnormalities: A Comprehensive Review. Journal of clinical medicine	MK Sin, JL Dage, K Nho, NM Dowling, NT Seyfried, DA Bennett, AI Levey, A Ahmed	02/07/2025
Simultaneous profiling of native-state proteomes and transcriptomes of neural cell types using proximity labeling. bioRxiv : the preprint server for biology	CC Ramelow, EB Dammer, H Xiao, L Cheng, P Kumar, C Espinosa-Garcia, MM Sampson, RS Nelson, S Malepati, D Kour, R Kumari, Q Guo, P Bagchi, DM Duong, NT Seyfried, SA Sloan, S Rangaraju	02/01/2025
Proximity labeling of the Tau repeat domain enriches RNA-binding proteins that are altered in Alzheimer's disease and related tauopathies. bioRxiv : the preprint server for biology	SM Shapley, A Shantaraman, MA Kearney, EB Dammer, DM Duong, CA Bowen, P Bagchi, Q Guo, S Rangaraju, NT Seyfried	01/22/2025
APOE Christchurch enhances a disease-associated microglial response to plaque but suppresses response to tau pathology. Molecular neurodegeneration	KM Tran, NE Kwang, CA Butler, A Gomez-Arboledas, S Kawauchi, C Mar, D Chao, RA Barahona, C Da Cunha, KI Tsourmas, Z Shi, S Wang, S Collins, A Walker, KX Shi, JA Alcantara, J Neumann, DM Duong, NT Seyfried, AJ Tenner, FM LaFerla, LA Hohsfield, V Swarup, GR MacGregor, KN Green	01/22/2025
Identification of novel Kv1.3 channel-interacting proteins using proximity labelling in T-cells. bioRxiv : the preprint server for biology	D Kour, CA Bowen, U Srivastava, HM Nguyen, R Kumari, P Kumar, AD Brandelli, S Bitarafan, BR Tobin, L Wood, NT Seyfried, H Wulff, S Rangaraju	01/18/2025
CSF proteomics reveals changes in myelin and synaptic biology after Spectris treatment. Alzheimer's & dementia (New York, N. Y.)	M Hajós, K Pandey, AC Singer, D Duong, S Bitarafan, M Shpokayte, Z Malchano, R Kern, JJ Lah, AI Levey, NT Seyfried	01/01/2025
Marmosets as model systems for the study of Alzheimer's disease and related dementias: Substantiation of physiological tau 3R and 4R isoform expression and phosphorylation. Alzheimer's & dementia : the journal of the Alzheimer's Association	H Huhe, SM Shapley, DM Duong, F Wu, SK Ha, SH Choi, J Kofler, Y Mou, TR Guimaraes, A Thathiah, CM Watson, LKH Schaeffer, GW Carter, NT Seyfried, AC Silva, SJ Sukoff Rizzo	01/01/2025
Stratifying risk of Alzheimer's disease in healthy middle-aged individuals with machine learning. Brain communications	R Tandon, L Zhao, CM Watson, N Sarkar, M Elmor, C Heilman, K Sanders, CM Hales, H Yang, DW Loring, FC Goldstein, JJ Hanfelt, DM Duong, ECB Johnson, AP Wingo, TS Wingo, BR Roberts, NT Seyfried, AI Levey, JJ Lah, CS Mitchell	01/01/2025
Biochemical and neurophysiological effects of deficiency of the mitochondrial import protein TIMM50. eLife	E Paz, S Jain, I Gottfried, O Staretz-Chacham, M Mahajnah, P Bagchi, NT Seyfried, U Ashery, A Azem	12/16/2024
Large-scale deep proteomic analysis in Alzheimer's disease brain regions across race and ethnicity. Alzheimer's & dementia : the journal of the Alzheimer's Association	F Seifar, EJ Fox, A Shantaraman, Y Liu, EB Dammer, E Modeste, DM Duong, L Yin, AN Trautwig, Q Guo, K Xu, L Ping, JS Reddy, M Allen, Z Quicksall, L Heath, J Scanlan, E Wang, M Wang, AV Linden, W Poehlman, X Chen, S Baheti, C Ho, T Nguyen, G Yepez, AO Mitchell, SR Oatman, X Wang, MM Carrasquillo, A Runnels, T Beach, GE Serrano, DW Dickson, EB Lee, TE Golde, S Prokop, LL Barnes, B Zhang, V Haroutunian, M Gearing, JJ Lah, P De Jager, DA Bennett, A Greenwood, N Ertekin-Taner, AI Levey, A Wingo, T Wingo, NT Seyfried	12/01/2024
Genetic architecture of epigenetic cortical clock age in brain tissue from older individuals: alterations in CD46 and other loci. Epigenetics	F Grodstein, B Lemos, J Yang, K de Paiva Lopes, RA Vialle, N Seyfried, Y Wang, G Shireby, E Hannon, A Thomas, K Brookes, J Mill, PL De Jager, DA Bennett	12/01/2024
Basic Science and Pathogenesis. Alzheimer's & dementia : the journal of the Alzheimer's Association	KF Afroz, Y Levites, D Ryu, Y Ran, JD Gadhavi, X Liu, NT Seyfried, T Golde	12/01/2024
Basic Science and Pathogenesis. Alzheimer's & dementia : the journal of the Alzheimer's Association	CC Ramelow, H Xiao, L Cheng, P Kumar, EB Dammer, M Sampson, RS Nelson, S Malepati, Q Quo, P Bagchi, DM Duong, NT Seyfried, SA Sloan, S Rangaraju	12/01/2024
Basic Science and Pathogenesis. Alzheimer's & dementia : the journal of the Alzheimer's Association	JS Reddy, LM Heath, M Allen, WL Poehlman, Y Wang, R Johnson, E Wang, Y Ma, CCG Ho, KP Lopes, AV Linden, Z Quicksall, X Chen, S Baheti, T Nguyen, G Yepez-Sisalema, AO Mitchell, SR Oatman, X Wang, MM Carrasquillo, A Runnels, AF Teich, TG Beach, GE Serrano, T Golde, LL Barnes, M Wang, V Haroutunian, B Zhang, PL De Jager, DA Bennett, NT Seyfried, A Greenwood, N Ertekin-Taner	12/01/2024
Basic Science and Pathogenesis. Alzheimer's & dementia : the journal of the Alzheimer's Association	P Zhao, OE Fadel, A Le, CG Mangleburg, T Wu, J Dhindsa, BK Amoh, AS Marella, Y Li, NT Seyfried, AI Levey, Z Liu, I Al-Ramahi, J Botas, JM Shulman	12/01/2024
Basic Science and Pathogenesis. Alzheimer's & dementia : the journal of the Alzheimer's Association	CA Bowen, HM Nguyen, YQ Lin, P Bagchi, A Natu, H Xiao, C Espinosa-Garcia, P Kumar, H Wulff, NT Seyfried, S Rangaraju	12/01/2024
Basic Science and Pathogenesis. Alzheimer's & dementia : the journal of the Alzheimer's Association	D Li-Kroeger, I Al-Ramahi, N Smith, A Marella, BK Amoh, S Saladi, J Botas, NT Seyfried, AI Levey, JM Shulman	12/01/2024
Basic Science and Pathogenesis. Alzheimer's & dementia : the journal of the Alzheimer's Association	SM Shapley, H Huhe, DM Duong, F Wu, GW Carter, AC Silva, SJS Rizzo, NT Seyfried	12/01/2024
Basic Science and Pathogenesis. Alzheimer's & dementia : the journal of the Alzheimer's Association	C Espinosa-Garcia, U Srivastava, P Kumar, BR Tobin, H Xiao, L Cheng, P Bagchi, DM Duong, NT Seyfried, V Faundez, LB Wood, S Rangaraju	12/01/2024
Biomarkers. Alzheimer's & dementia : the journal of the Alzheimer's Association	M Shpokayte, K Pandey, AC Singer, D Doung, JJ Lah, AI Levey, NT Seyfried, Z Malchano, R Kern, M Hajos	12/01/2024
Biomarkers. Alzheimer's & dementia : the journal of the Alzheimer's Association	R Batra, M Arnold, X Wang, M Allen, MA Wörheide, C Blach, AI Levey, NT Seyfried, DA Bennett, G Kastenmuller, N Ertekin-Taner, R Kaddurah-Daouk, J Krumsiek	12/01/2024
Biomarkers. Alzheimer's & dementia : the journal of the Alzheimer's Association	JJ Lah, BR Roberts, CM Watson, ECB Johnson, CM Hales, D Qiu, TS Wingo, NT Seyfried, A Jeromin, AI Levey	12/01/2024
Biomarkers. Alzheimer's & dementia : the journal of the Alzheimer's Association	F Seifar, EJ Fox, A Shantaraman, Y Liu, ES Modeste, DM Duong, L Yin, M Gearing, JJ Lah, JS Reddy, M Allen, Z Quicksall, LM Heath, J Scanlan, E Wang, M Wang, AV Linden, WL Poehlman, X Chen, S Baheti, CCG Ho, T Nguyen, G Yepez-Sisalema, AO Mitchell, SR Oatman, X Wang, MM Carrasquillo, A Runnels, TG Beach, T Golde, LL Barnes, V Haroutunian, B Zhang, PL Jager, DA Bennett, A Greenwood, N Ertekin-Taner, AI Levey, AP Wingo, TS Wingo, NT Seyfried	12/01/2024
Biomarkers. Alzheimer's & dementia : the journal of the Alzheimer's Association	A Tfaily, U Srivastava, S Rayaprolu, P Kumar, H Xiao, DM Duong, EB Dammer, NT Seyfried, S Rangaraju	12/01/2024
Developing Topics. Alzheimer's & dementia : the journal of the Alzheimer's Association	E Cho, J Caldwell, K Pandey, DM Duong, NT Seyfried, AO Caggiano, VD Caro, ME Hamby	12/01/2024
Developing Topics. Alzheimer's & dementia : the journal of the Alzheimer's Association	LA Fish, M Telpoukhovskaia, J Algoo, N Hadad, B Gurdon, M Dai, AR Ouellette, SM Neuner, AR Dunn, JAL Willcox, Y Wu, LC Dumitrescu, O Bellur, J Zhang, KM O'Connell, EB Dammer, NT Seyfried, S Muzumdar, J Gillis, P Robson, M Arnold, TJ Hohman, VM Philip, V Menon, CC Kaczorowski	12/01/2024
Developing Topics. Alzheimer's & dementia : the journal of the Alzheimer's Association	VD Caro, BN Lizama, E Cho, DM Duong, K Pandey, K Blennow, H Zetterberg, AI Levey, C Teunissen, AO Caggiano, NT Seyfried, ME Hamby	12/01/2024
Developing Topics. Alzheimer's & dementia : the journal of the Alzheimer's Association	JH Lee, P Stavrides, S Darji, MJ Berg, CN Goulbourne, PS Mohan, C Bleiwas, J Peddy, EB Dammer, NT Seyfried, RA Nixon	12/01/2024
Integration across biophysical scales identifies molecular and cellular correlates of person-to-person variability in human brain connectivity. Nature neuroscience	B Ng, S Tasaki, KM Greathouse, CK Walker, A Zhang, S Covitz, M Cieslak, AJ Weber, AB Adamson, JP Andrade, EH Poovey, KA Curtis, HM Muhammad, J Seidlitz, T Satterthwaite, DA Bennett, NT Seyfried, J Vogel, C Gaiteri, JH Herskowitz	11/01/2024
Network Analysis of Brain and Bone Tissue Transcripts Reveals Shared Molecular Mechanisms Underlying Alzheimer's Disease and Related Dementias and Osteoporosis. The journals of gerontology. Series A, Biological sciences and medical sciences	A Nagarajan, J Laird, O Ugochukwu, S Reppe, K Gautvik, RD Ross, DA Bennett, C Rosen, DP Kiel, LA Higginbotham, NT Seyfried, CW Lary	11/01/2024
CSF proteomics identifies early changes in autosomal dominant Alzheimer's disease. Cell	Y Shen, J Timsina, G Heo, A Beric, M Ali, C Wang, C Yang, Y Wang, D Western, M Liu, P Gorijala, J Budde, A Do, H Liu, B Gordon, JJ Llibre-Guerra, N Joseph-Mathurin, RJ Perrin, D Maschi, T Wyss-Coray, P Pastor, AE Renton, EI Surace, ECB Johnson, AI Levey, I Alvarez, J Levin, JM Ringman, RF Allegri, N Seyfried, GS Day, Q Wu, MV Fernández, R Tarawneh, E McDade, JC Morris, RJ Bateman, A Goate, L Ibanez, YJ Sung, C Cruchaga	10/31/2024
Correction: Network proteomics of the Lewy body dementia brain reveals presynaptic signatures distinct from Alzheimer's disease. Molecular neurodegeneration	A Shantaraman, EB Dammer, O Ugochukwu, DM Duong, L Yin, EK Carter, M Gearing, A Chen-Plotkin, EB Lee, JQ Trojanowski, DA Bennett, JJ Lah, AI Levey, NT Seyfried, L Higginbotham	10/11/2024
Heparin-enriched plasma proteome is significantly altered in Alzheimer's disease. Molecular neurodegeneration	Q Guo, L Ping, EB Dammer, DM Duong, L Yin, K Xu, A Shantaraman, EJ Fox, TE Golde, ECB Johnson, BR Roberts, JJ Lah, AI Levey, NT Seyfried	10/08/2024
Alzheimer's disease risk gene CD2AP is a dose-sensitive determinant of synaptic structure and plasticity. Human molecular genetics	M Pavešković, RB De-Paula, SA Ojelade, EK Tantry, MY Kochukov, S Bao, S Veeraragavan, AR Garza, S Srivastava, SY Song, M Fujita, DM Duong, DA Bennett, PL De Jager, NT Seyfried, ME Dickinson, JD Heaney, BR Arenkiel, JM Shulman	10/07/2024
Bridging the gap: Multi-omics profiling of brain tissue in Alzheimer's disease and older controls in multi-ethnic populations. Alzheimer's & dementia : the journal of the Alzheimer's Association	JS Reddy, L Heath, AV Linden, M Allen, KP Lopes, F Seifar, E Wang, Y Ma, WL Poehlman, ZS Quicksall, A Runnels, Y Wang, DM Duong, L Yin, K Xu, ES Modeste, A Shantaraman, EB Dammer, L Ping, SR Oatman, J Scanlan, C Ho, MM Carrasquillo, M Atik, G Yepez, AO Mitchell, TT Nguyen, X Chen, DX Marquez, H Reddy, H Xiao, S Seshadri, R Mayeux, S Prokop, EB Lee, GE Serrano, TG Beach, AF Teich, V Haroutunian, EJ Fox, M Gearing, A Wingo, T Wingo, JJ Lah, AI Levey, DW Dickson, LL Barnes, P De Jager, B Zhang, D Bennett, NT Seyfried, AK Greenwood, N Ertekin-Taner	10/01/2024
CT1812 biomarker signature from a meta-analysis of CSF proteomic findings from two Phase 2 clinical trials in Alzheimer's disease. Alzheimer's & dementia : the journal of the Alzheimer's Association	BN Lizama, C Williams, HA North, K Pandey, D Duong, V Di Caro, AP Mecca, K Blennow, H Zetterberg, AI Levey, M Grundman, CH van Dyck, AO Caggiano, NT Seyfried, ME Hamby	10/01/2024
Serum proteomics reveal APOE-ε4-dependent and APOE-ε4-independent protein signatures in Alzheimer's disease. Nature aging	EA Frick, V Emilsson, T Jonmundsson, AE Steindorsdottir, ECB Johnson, R Puerta, EB Dammer, A Shantaraman, A Cano, M Boada, S Valero, P García-González, EF Gudmundsson, A Gudjonsson, R Pitts, X Qiu, N Finkel, JJ Loureiro, AP Orth, NT Seyfried, AI Levey, A Ruiz, T Aspelund, LL Jennings, LJ Launer, V Gudmundsdottir, V Gudnason	10/01/2024
Biochemical and neurophysiological effects of deficiency of the mitochondrial import protein TIMM50. bioRxiv : the preprint server for biology	E Paz, S Jain, I Gottfried, O Staretz-Chacham, M Mahajnah, P Bagchi, NT Seyfried, U Ashery, A Azem	09/21/2024
Entorhinal cortex vulnerability to human APP expression promotes hyperexcitability and tau pathology. Nature communications	AM Goettemoeller, E Banks, P Kumar, VJ Olah, KE McCann, K South, CC Ramelow, A Eaton, DM Duong, NT Seyfried, D Weinshenker, S Rangaraju, MJM Rowan	09/10/2024
Omnibus proteome-wide association study identifies 43 risk genes for Alzheimer disease dementia. American journal of human genetics	T Hu, RL Parrish, Q Dai, AS Buchman, S Tasaki, DA Bennett, NT Seyfried, MP Epstein, J Yang	09/05/2024
Proteome-wide association studies using summary pQTL data of three tissues identified 30 risk genes of Alzheimer's disease dementia. medRxiv : the preprint server for health sciences	T Hu, Q Liu, Q Dai, RL Parrish, AS Buchman, S Tasaki, NT Seyfried, Y Wang, DA Bennett, PL De Jager, MP Epstein, J Yang	09/04/2024
Integrative proteomics identifies a conserved Aβ amyloid responsome, novel plaque proteins, and pathology modifiers in Alzheimer's disease. Cell reports. Medicine	Y Levites, EB Dammer, Y Ran, W Tsering, D Duong, M Abreha, J Gadhavi, K Lolo, J Trejo-Lopez, J Phillips, A Iturbe, A Erquizi, BD Moore, D Ryu, A Natu, K Dillon, J Torrellas, C Moran, T Ladd, F Afroz, T Islam, J Jagirdar, CC Funk, M Robinson, S Rangaraju, DR Borchelt, N Ertekin-Taner, JW Kelly, FL Heppner, ECB Johnson, K McFarland, AI Levey, S Prokop, NT Seyfried, TE Golde	08/20/2024
Structural variants linked to Alzheimer's Disease and other common age-related clinical and neuropathologic traits. medRxiv : the preprint server for health sciences	RA Vialle, K de Paiva Lopes, Y Li, B Ng, JA Schneider, AS Buchman, Y Wang, JM Farfel, LL Barnes, AP Wingo, TS Wingo, NT Seyfried, PL De Jager, C Gaiteri, S Tasaki, DA Bennett	08/13/2024
Dendritic spine head diameter predicts episodic memory performance in older adults. Science advances	CK Walker, E Liu, KM Greathouse, AB Adamson, JP Wilson, EH Poovey, KA Curtis, HM Muhammad, AJ Weber, DA Bennett, NT Seyfried, C Gaiteri, JH Herskowitz	08/09/2024
Network proteomics of the Lewy body dementia brain reveals presynaptic signatures distinct from Alzheimer's disease. Molecular neurodegeneration	A Shantaraman, EB Dammer, O Ugochukwu, DM Duong, L Yin, EK Carter, M Gearing, A Chen-Plotkin, EB Lee, JQ Trojanowski, DA Bennett, JJ Lah, AI Levey, NT Seyfried, L Higginbotham	08/06/2024
Proteomic networks of gray and white matter reveal tissue-specific changes in human tauopathy. Annals of clinical and translational neurology	AG Johnson, EB Dammer, JA Webster, DM Duong, NT Seyfried, CM Hales	08/01/2024
Proximity Labeling Proteomics Reveals Kv1.3 Potassium Channel Immune Interactors in Microglia. Molecular & cellular proteomics : MCP	CA Bowen, HM Nguyen, Y Lin, P Bagchi, A Natu, C Espinosa-Garcia, E Werner, R Kumari, AD Brandelli, P Kumar, BR Tobin, L Wood, V Faundez, H Wulff, NT Seyfried, S Rangaraju	08/01/2024
Contributions of genetic variation in astrocytes to cell and molecular mechanisms of risk and resilience to late onset Alzheimer's disease. bioRxiv : the preprint server for biology	H Lee, RV Pearse, AM Lish, C Pan, ZM Augur, G Terzioglu, P Gaur, M Liao, M Fujita, ES Tio, DM Duong, D Felsky, NT Seyfried, V Menon, DA Bennett, PL De Jager, TL Young-Pearse	07/31/2024
Entorhinal cortex vulnerability to human APP expression promotes hyperexcitability and tau pathology. bioRxiv : the preprint server for biology	AM Goettemoeller, E Banks, P Kumar, VJ Olah, KE McCann, K South, CC Ramelow, A Eaton, DM Duong, NT Seyfried, D Weinshenker, S Rangaraju, MJ Rowan	07/05/2024
Psychosocial experiences are associated with human brain mitochondrial biology. Proceedings of the National Academy of Sciences of the United States of America	C Trumpff, AS Monzel, C Sandi, V Menon, HU Klein, M Fujita, A Lee, VA Petyuk, C Hurst, DM Duong, NT Seyfried, AP Wingo, TS Wingo, Y Wang, M Thambisetty, L Ferrucci, DA Bennett, PL De Jager, M Picard	07/02/2024
Proteins linking APOE ɛ4 with Alzheimer's disease. Alzheimer's & dementia : the journal of the Alzheimer's Association	S Oveisgharan, L Yu, K de Paiva Lopes, S Tasaki, Y Wang, V Menon, JA Schneider, NT Seyfried, DA Bennett	07/01/2024
Proteomic analysis of Alzheimer's disease cerebrospinal fluid reveals alterations associated with APOE ε4 and atomoxetine treatment. Science translational medicine	EB Dammer, A Shantaraman, L Ping, DM Duong, ES Gerasimov, SP Ravindran, V Gudmundsdottir, EA Frick, GT Gomez, KA Walker, V Emilsson, LL Jennings, V Gudnason, D Western, C Cruchaga, JJ Lah, TS Wingo, AP Wingo, NT Seyfried, AI Levey, ECB Johnson	06/26/2024
Proteomic changes in the human cerebrovasculature in Alzheimer's disease and related tauopathies linked to peripheral biomarkers in plasma and cerebrospinal fluid. Alzheimer's & dementia : the journal of the Alzheimer's Association	AM Wojtas, EB Dammer, Q Guo, L Ping, A Shantaraman, DM Duong, L Yin, EJ Fox, F Seifar, EB Lee, ECB Johnson, JJ Lah, AI Levey, Y Levites, S Rangaraju, TE Golde, NT Seyfried	06/01/2024
Lowering Hippocampal miR-29a Expression Slows Cognitive Decline and Reduces Beta-Amyloid Deposition in 5×FAD Mice. Molecular neurobiology	Z Mei, J Liu, JP Schroeder, D Weinshenker, DM Duong, NT Seyfried, Y Li, P Jin, AP Wingo, TS Wingo	06/01/2024
Systems biology dissection of PTSD and MDD across brain regions, cell types, and blood. Science (New York, N.Y.)	NP Daskalakis, A Iatrou, C Chatzinakos, A Jajoo, C Snijders, D Wylie, CP DiPietro, I Tsatsani, CY Chen, CD Pernia, M Soliva-Estruch, D Arasappan, RA Bharadwaj, L Collado-Torres, S Wuchty, VE Alvarez, EB Dammer, A Deep-Soboslay, DM Duong, N Eagles, BR Huber, L Huuki, VL Holstein, MW Logue, JF Lugenbühl, AX Maihofer, MW Miller, CM Nievergelt, G Pertea, D Ross, MSE Sendi, BB Sun, R Tao, J Tooke, EJ Wolf, Z Zeier, S Berretta, FA Champagne, T Hyde, NT Seyfried, JH Shin, DR Weinberger, CB Nemeroff, JE Kleinman, KJ Ressler	05/24/2024
Associations of brain morphology with cortical proteins of cognitive resilience. Neurobiology of aging	VN Poole, AR Ridwan, K Arfanakis, RJ Dawe, NT Seyfried, PL De Jager, JA Schneider, SE Leurgans, L Yu, DA Bennett	05/01/2024
Marmosets as model systems for the study of Alzheimer's disease and related dementias: substantiation of physiological Tau 3R and 4R isoform expression and phosphorylation. bioRxiv : the preprint server for biology	H Huhe, SM Shapley, D Duong, F Wu, SK Ha, SH Choi, J Kofler, Y Mou, TR Guimaraes, A Thathiah, LKH Schaeffer, GW Carter, NT Seyfried, AC Silva, SJ Sukoff Rizzo	04/29/2024
Large-scale Deep Proteomic Analysis in Alzheimer's Disease Brain Regions Across Race and Ethnicity. bioRxiv : the preprint server for biology	F Seifar, EJ Fox, A Shantaraman, Y Liu, EB Dammer, E Modeste, DM Duong, L Yin, AN Trautwig, Q Guo, K Xu, L Ping, JS Reddy, M Allen, Z Quicksall, L Heath, J Scanlan, E Wang, M Wang, AV Linden, W Poehlman, X Chen, S Baheti, C Ho, T Nguyen, G Yepez, AO Mitchell, SR Oatman, X Wang, MM Carrasquillo, A Runnels, T Beach, GE Serrano, DW Dickson, EB Lee, TE Golde, S Prokop, LL Barnes, B Zhang, V Haroutunian, M Gearing, JJ Lah, P Jager, DA Bennett, A Greenwood, N Ertekin-Taner, AI Levey, A Wingo, T Wingo, NT Seyfried	04/26/2024
Bridging the Gap: Multi-Omics Profiling of Brain Tissue in Alzheimer's Disease and Older Controls in Multi-Ethnic Populations. bioRxiv : the preprint server for biology	JS Reddy, L Heath, A Vander Linden, M Allen, K de Paiva Lopes, F Seifar, E Wang, Y Ma, WL Poehlman, ZS Quicksall, A Runnels, Y Wang, DM Duong, L Yin, K Xu, ES Modeste, A Shantaraman, EB Dammer, L Ping, SR Oatman, J Scanlan, C Ho, MM Carrasquillo, M Atik, G Yepez, AO Mitchell, TT Nguyen, X Chen, DX Marquez, H Reddy, H Xiao, S Seshadri, R Mayeux, S Prokop, EB Lee, GE Serrano, TG Beach, AF Teich, V Haroutunian, EJ Fox, M Gearing, A Wingo, T Wingo, JJ Lah, AI Levey, DW Dickson, LL Barnes, P De Jager, B Zhang, D Bennett, NT Seyfried, AK Greenwood, N Ertekin-Taner	04/20/2024
Glycoproteome-Wide Discovery of Cortical Glycoproteins That May Provide Cognitive Resilience in Older Adults. Neurology	AS Buchman, L Yu, HU Klein, AR Zammit, S Oveisgharan, S Nag, N Tickotsky, H Levy, N Seyfried, D Morgenstern, Y Levin, M Schnaider Beeri, DA Bennett	04/09/2024
Person-specific differences in ubiquitin-proteasome mediated proteostasis in human neurons. Alzheimer's & dementia : the journal of the Alzheimer's Association	YC Hsieh, ZM Augur, M Arbery, N Ashour, K Barrett, RV Pearse, ES Tio, DM Duong, D Felsky, PL De Jager, DA Bennett, NT Seyfried, TL Young-Pearse	04/01/2024
Native-state proteomics of Parvalbumin interneurons identifies unique molecular signatures and vulnerabilities to early Alzheimer's pathology. Nature communications	P Kumar, AM Goettemoeller, C Espinosa-Garcia, BR Tobin, A Tfaily, RS Nelson, A Natu, EB Dammer, JV Santiago, S Malepati, L Cheng, H Xiao, DD Duong, NT Seyfried, LB Wood, MJM Rowan, S Rangaraju	04/01/2024
Large-scale network analysis of the cerebrospinal fluid proteome identifies molecular signatures of frontotemporal lobar degeneration. Research square	R Saloner, A Staffaroni, E Dammer, ECB Johnson, E Paolillo, A Wise, H Heuer, L Forsberg, AL Lago, J Webb, J Vogel, A Santillo, O Hansson, J Kramer, B Miller, J Li, J Loureiro, R Sivasankaran, K Worringer, N Seyfried, J Yokoyama, W Seeley, S Spina, L Grinberg, L VandeVrede, P Ljubenkov, E Bayram, A Bozoki, D Brushaber, C Considine, G Day, B Dickerson, K Domoto-Reilly, K Faber, D Galasko, D Geschwind, N Ghoshal, N Graff-Radford, C Hales, L Honig, GY Hsiung, E Huey, J Kornak, W Kremers, M Lapid, S Lee, I Litvan, C McMillan, M Mendez, T Miyagawa, A Pantelyat, B Pascual, H Paulson, L Petrucelli, P Pressman, E Ramos, K Rascovsky, E Roberson, R Savica, A Snyder, AC Sullivan, C Tartaglia, M Vandebergh, B Boeve, H Rosen, J Rojas, A Boxer, K Casaletto	03/28/2024
Integrative brain omics approach reveals key role for sn-1 lysophosphatidylethanolamine in Alzheimer's dementia. Research square	E Ortlund, CY Chen, K Maner-Smith, M Khadka, J Ahn, X Gulbin, A Ivanova, E Dammer, N Seyfried, D Bennett, I Hajjar	02/27/2024
Heparin-enriched plasma proteome is significantly altered in Alzheimer's Disease. Research square	Q Guo, L Ping, EB Dammer, L Yin, K Xu, A Shantaraman, EJ Fox, TE Golde, ECB Johnson, BR Roberts, JJ Lah, AI Levey, NT Seyfried	02/23/2024
Mis-spliced transcripts generate de novo proteins in TDP-43-related ALS/FTD. Science translational medicine	S Seddighi, YA Qi, AL Brown, OG Wilkins, C Bereda, C Belair, YJ Zhang, M Prudencio, MJ Keuss, A Khandeshi, S Pickles, SE Kargbo-Hill, J Hawrot, DM Ramos, H Yuan, J Roberts, EK Sacramento, SI Shah, MA Nalls, JM Colón-Mercado, JF Reyes, VH Ryan, MP Nelson, CN Cook, Z Li, L Screven, JY Kwan, PR Mehta, M Zanovello, M Hallegger, A Shantaraman, L Ping, Y Koike, B Oskarsson, NP Staff, DM Duong, A Ahmed, M Secrier, J Ule, S Jacobson, DS Reich, JD Rohrer, A Malaspina, DW Dickson, JD Glass, A Ori, NT Seyfried, M Maragkakis, L Petrucelli, P Fratta, ME Ward	02/14/2024
Cryptic exon inclusion is a molecular signature of LATE-NC in aging brains. Acta neuropathologica	M Chung, EK Carter, AM Veire, EB Dammer, J Chang, DM Duong, N Raj, GJ Bassell, JD Glass, TF Gendron, PT Nelson, AI Levey, NT Seyfried, ZT McEachin	02/03/2024
Network Proteomics of the Lewy Body Dementia Brain Reveals Presynaptic Signatures Distinct from Alzheimer's Disease. bioRxiv : the preprint server for biology	A Shantaraman, EB Dammer, O Ugochukwu, DM Duong, L Yin, EK Carter, M Gearing, A Chen-Plotkin, EB Lee, JQ Trojanowski, DA Bennett, JJ Lah, AI Levey, NT Seyfried, L Higginbotham	01/24/2024
TMEM106B core deposition associates with TDP-43 pathology and is increased in risk SNP carriers for frontotemporal dementia. Science translational medicine	JD Marks, VE Ayuso, Y Carlomagno, M Yue, TW Todd, Y Hao, Z Li, ZT McEachin, A Shantaraman, DM Duong, LM Daughrity, K Jansen-West, W Shao, A Calliari, JG Bejarano, M DeTure, B Rawlinson, MC Casey, MT Lilley, MH Donahue, VM Jawahar, BF Boeve, RC Petersen, DS Knopman, B Oskarsson, NR Graff-Radford, ZK Wszolek, DW Dickson, KA Josephs, YA Qi, NT Seyfried, ME Ward, YJ Zhang, M Prudencio, L Petrucelli, CN Cook	01/17/2024
Systematic proteomics in Autosomal dominant Alzheimer's disease reveals decades-early changes of CSF proteins in neuronal death, and immune pathways. medRxiv : the preprint server for health sciences	Y Shen, M Ali, J Timsina, C Wang, A Do, D Western, M Liu, P Gorijala, J Budde, H Liu, B Gordon, E McDade, JC Morris, JJ Llibre-Guerra, RJ Bateman, N Joseph-Mathurin, RJ Perrin, D Maschi, T Wyss-Coray, P Pastor, A Goate, AE Renton, EI Surace, ECB Johnson, AI Levey, I Alvarez, J Levin, JM Ringman, RF Allegri, N Seyfried, GS Day, Q Wu, MV Fernández, L Ibanez, YJ Sung, C Cruchaga	01/13/2024
Proteomic Changes in the Human Cerebrovasculature in Alzheimer's Disease and Related Tauopathies Linked to Peripheral Biomarkers in Plasma and Cerebrospinal Fluid. medRxiv : the preprint server for health sciences	AM Wojtas, EB Dammer, Q Guo, L Ping, A Shantaraman, DM Duong, L Yin, EJ Fox, F Seifar, EB Lee, ECB Johnson, JJ Lah, AI Levey, Y Levites, S Rangaraju, TE Golde, NT Seyfried	01/11/2024
OXR1 maintains the retromer to delay brain aging under dietary restriction. Nature communications	KA Wilson, S Bar, EB Dammer, EM Carrera, BA Hodge, TAU Hilsabeck, J Bons, GW Brownridge, JN Beck, J Rose, M Granath-Panelo, CS Nelson, G Qi, AA Gerencser, J Lan, A Afenjar, G Chawla, RB Brem, PM Campeau, HJ Bellen, B Schilling, NT Seyfried, LM Ellerby, P Kapahi	01/11/2024
Proteome-wide Analyses Identified Cortical Proteins Associated With Resilience for Varied Cognitive Abilities. Neurology	AR Zammit, HU Klein, L Yu, AI Levey, NT Seyfried, AP Wingo, TS Wingo, JA Schneider, DA Bennett, AS Buchman	01/09/2024
Serum proteomics reveals APOE dependent and independent protein signatures in Alzheimer's disease. Research square	V Gudmundsdottir, E Frick, V Emilsson, T Jonmundsson, A Steindorsdottir, ECB Johnson, R Puerta, E Dammer, A Shantaraman, A Cano, M Boada, S Valero, P Garcia-Gonzalez, E Gudmundsson, A Gudjonsson, R Pitts, X Qiu, N Finkel, J Loureiro, A Orth, N Seyfried, A Levey, A Ruiz, T Aspelund, L Jennings, L Launer, V Gudnason	01/09/2024
Proteomic Signaling of Dual-Specificity Phosphatase 4 (DUSP4) in Alzheimer's Disease. Biomolecules	E Wang, AL Pan, P Bagchi, S Rangaraju, NT Seyfried, ME Ehrlich, SR Salton, B Zhang	01/03/2024
Associations of cortical SPP1 and ITGAX with cognition and common neuropathologies in older adults. Alzheimer's & dementia : the journal of the Alzheimer's Association	KP Lopes, L Yu, X Shen, Y Qiu, S Tasaki, A Iatrou, MS Beeri, NT Seyfried, V Menon, Y Wang, JA Schneider, H Cantor, DA Bennett	01/01/2024
Using deep long-read RNAseq in Alzheimer's disease brain to assess medical relevance of RNA isoform diversity. bioRxiv : the preprint server for biology	BA Heberle, JA Brandon, ML Page, KA Nations, KI Dikobe, BJ White, LA Gordon, GA Fox, ME Wadsworth, PH Doyle, BA Williams, EJ Fox, A Shantaraman, M Ryten, S Goodwin, E Ghiban, R Wappel, S Mavruk-Eskipehlivan, JB Miller, NT Seyfried, PT Nelson, JD Fryer, MTW Ebbert	12/11/2023
Aβ Amyloid Scaffolds the Accumulation of Matrisome and Additional Proteins in Alzheimer's Disease. bioRxiv : the preprint server for biology	Y Levites, EB Dammer, Y Ran, W Tsering, D Duong, M Abreha, J Gadhavi, K Lolo, J Trejo-Lopez, JL Phillips, A Iturbe, A Erqiuzi, BD Moore, D Ryu, A Natu, KD Dillon, J Torrellas, C Moran, TB Ladd, KF Afroz, T Islam, J Jagirdar, CC Funk, M Robinson, DR Borchelt, N Ertekin-Taner, JW Kelly, FL Heppner, EC Johnson, K McFarland, AL Levey, S Prokop, NT Seyfried, TE Golde	12/07/2023
Identification of State-Specific Proteomic and Transcriptomic Signatures of Microglia-Derived Extracellular Vesicles. Molecular & cellular proteomics : MCP	JV Santiago, A Natu, CC Ramelow, S Rayaprolu, H Xiao, V Kumar, P Kumar, NT Seyfried, S Rangaraju	12/01/2023
INPP5D regulates inflammasome activation in human microglia. Nature communications	V Chou, RV Pearse, AJ Aylward, N Ashour, M Taga, G Terzioglu, M Fujita, SB Fancher, A Sigalov, CR Benoit, H Lee, M Lam, NT Seyfried, DA Bennett, PL De Jager, V Menon, TL Young-Pearse	11/29/2023
Serum proteomics reveals APOE dependent and independent protein signatures in Alzheimer's disease. medRxiv : the preprint server for health sciences	EA Frick, V Emilsson, T Jonmundsson, AE Steindorsdottir, ECB Johnson, R Puerta, EB Dammer, A Shantaraman, A Cano, M Boada, S Valero, P García-González, EF Gudmundsson, A Gudjonsson, JJ Loureiro, AP Orth, NT Seyfried, AI Levey, A Ruiz, T Aspelund, LL Jennings, LJ Launer, V Gudmundsdottir, V Gudnason	11/09/2023
Neuronal Glycogen Breakdown Mitigates Tauopathy via Pentose Phosphate Pathway-Mediated Oxidative Stress Reduction. Research square	S Bar, KA Wilson, TAU Hilsabeck, S Alderfer, EB Dammer, JB Burton, S Shah, A Holtz, EM Carrera, JN Beck, JH Chen, G Kauwe, TE Tracy, NT Seyfried, B Schilling, LM Ellerby, P Kapahi	11/08/2023
Entorhinal cortex vulnerability to human APP expression promotes hyperexcitability and tau pathology. Research square	AM Goettemoeller, E Banks, KE McCann, P Kumar, K South, VJ Olah, CC Ramelow, DM Duong, NT Seyfried, S Rangaraju, D Weinshenker, MJ Rowan	11/06/2023
Proteomic Network Analysis of Alzheimer's Disease Cerebrospinal Fluid Reveals Alterations Associated with APOE ε4 Genotype and Atomoxetine Treatment. medRxiv : the preprint server for health sciences	EB Dammer, A Shantaraman, L Ping, DM Duong, ES Gerasimov, SP Ravindran, V Gudmundsdottir, EA Frick, GT Gomez, KA Walker, V Emilsson, LL Jennings, V Gudnason, D Western, C Cruchaga, JJ Lah, TS Wingo, AP Wingo, NT Seyfried, AI Levey, ECB Johnson	10/30/2023
Proteomic signaling of dual specificity phosphatase 4 (DUSP4) in Alzheimer's disease. Research square	E Wang, AL Pan, P Bagchi, S Ranjaraju, NT Seyfried, ME Ehrlich, SR Salton, B Zhang	10/19/2023
Unbiased classification of the elderly human brain proteome resolves distinct clinical and pathophysiological subtypes of cognitive impairment. Neurobiology of disease	L Higginbotham, EK Carter, EB Dammer, RU Haque, ECB Johnson, DM Duong, L Yin, PL De Jager, DA Bennett, D Felsky, ES Tio, JJ Lah, AI Levey, NT Seyfried	10/01/2023
Proteomic signaling of dual specificity phosphatase 4 (DUSP4) in Alzheimer's disease. bioRxiv : the preprint server for biology	E Wang, AL Pan, P Bagchi, S Ranjaraju, NT Seyfried, ME Ehrlich, SR Salton, B Zhang	09/14/2023
A protein panel in cerebrospinal fluid for diagnostic and predictive assessment of Alzheimer's disease. Science translational medicine	R Haque, CM Watson, J Liu, EK Carter, DM Duong, JJ Lah, AP Wingo, BR Roberts, ECB Johnson, AJ Saykin, LM Shaw, NT Seyfried, TS Wingo, AI Levey	09/06/2023
Sex differences in brain protein expression and disease. Nature medicine	AP Wingo, Y Liu, ES Gerasimov, SM Vattathil, J Liu, DJ Cutler, MP Epstein, GAM Blokland, M Thambisetty, JC Troncoso, DM Duong, DA Bennett, AI Levey, NT Seyfried, TS Wingo	09/01/2023
Cell-type-specific regulation of APOE and CLU levels in human neurons by the Alzheimer's disease risk gene SORL1. Cell reports	H Lee, AJ Aylward, RV Pearse, AM Lish, YC Hsieh, ZM Augur, CR Benoit, V Chou, A Knupp, C Pan, S Goberdhan, DM Duong, NT Seyfried, DA Bennett, MF Taga, K Huynh, M Arnold, PJ Meikle, PL De Jager, V Menon, JE Young, TL Young-Pearse	08/29/2023
DNA-PK is activated by SIRT2 deacetylation to promote DNA double-strand break repair by non-homologous end joining. Nucleic acids research	PE Head, P Kapoor-Vazirani, GP Nagaraju, H Zhang, SK Rath, NC Luong, R Haji-Seyed-Javadi, F Sesay, SY Wang, DM Duong, W Daddacha, EV Minten, B Song, D Danelia, X Liu, S Li, EA Ortlund, NT Seyfried, DM Smalley, Y Wang, X Deng, WS Dynan, B El-Rayes, AJ Davis, DS Yu	08/25/2023
Integration of plasma and CSF metabolomics with CSF proteomic reveals novel associations between lipid mediators and central nervous system vascular and energy metabolism. Scientific reports	K Borkowski, NT Seyfried, M Arnold, JJ Lah, AI Levey, CM Hales, EB Dammer, C Blach, G Louie, R Kaddurah-Daouk, JW Newman	08/23/2023
Lowering hippocampal miR-29a expression slows cognitive decline and reduces beta-amyloid deposition in 5xFAD mice. Research square	Z Mei, J Liu, JP Schroeder, D Weinshenker, DM Duong, NT Seyfried, Y Li, P Jin, AP Wingo, TS Wingo	08/16/2023
Pathogenesis of Alzheimer's disease: Involvement of the choroid plexus. Alzheimer's & dementia : the journal of the Alzheimer's Association	M Čarna, IG Onyango, S Katina, D Holub, JS Novotny, M Nezvedova, D Jha, Z Nedelska, V Lacovich, TV Vyvere, R Houbrechts, K Garcia-Mansfield, R Sharma, V David-Dirgo, M Vyhnalek, K Texlova, H Chaves, N Bakkar, L Pertierra, M Vinkler, H Markova, J Laczo, K Sheardova, M Hortova-Kohoutkova, J Frič, G Forte, P Kaňovsky, S Belaškova, J Damborsky, J Hort, NT Seyfried, R Bowser, G Sevlever, RA Rissman, RA Smith, M Hajduch, P Pirrotte, Z Spacil, EB Dammer, C Limbäck-Stokin, GB Stokin	08/01/2023
Cerebrospinal fluid proteomics define the natural history of autosomal dominant Alzheimer's disease. Nature medicine	ECB Johnson, S Bian, RU Haque, EK Carter, CM Watson, BA Gordon, L Ping, DM Duong, MP Epstein, E McDade, NR Barthélemy, CM Karch, C Xiong, C Cruchaga, RJ Perrin, AP Wingo, TS Wingo, JP Chhatwal, GS Day, JM Noble, SB Berman, R Martins, NR Graff-Radford, PR Schofield, T Ikeuchi, H Mori, J Levin, M Farlow, JJ Lah, C Haass, M Jucker, JC Morris, TLS Benzinger, BR Roberts, RJ Bateman, AM Fagan, NT Seyfried, AI Levey	08/01/2023
Identification of state-specific proteomic and transcriptomic signatures of microglia-derived extracellular vesicles. bioRxiv : the preprint server for biology	JV Santiago, A Natu, CC Ramelow, S Rayaprolu, H Xiao, V Kumar, NT Seyfried, S Rangaraju	07/29/2023
A Molecular Basis of Human Brain Connectivity. bioRxiv : the preprint server for biology	B Ng, S Tasaki, KM Greathouse, CK Walker, A Zhang, S Covitz, M Cieslak, AB Adamson, JP Andrade, EH Poovey, KA Curtis, HM Muhammad, J Seidlitz, T Satterthwaite, DA Bennett, NT Seyfried, J Vogel, C Gaiteri, JH Herskowitz	07/24/2023
Quantitative proteomics of cerebrospinal fluid from African Americans and Caucasians reveals shared and divergent changes in Alzheimer's disease. Molecular neurodegeneration	ES Modeste, L Ping, CM Watson, DM Duong, EB Dammer, ECB Johnson, BR Roberts, JJ Lah, AI Levey, NT Seyfried	07/19/2023
Proteomics of brain, CSF, and plasma identifies molecular signatures for distinguishing sporadic and genetic Alzheimer's disease. Science translational medicine	YJ Sung, C Yang, J Norton, M Johnson, A Fagan, RJ Bateman, RJ Perrin, JC Morris, MR Farlow, JP Chhatwal, PR Schofield, H Chui, F Wang, B Novotny, A Eteleeb, C Karch, SE Schindler, H Rhinn, ECB Johnson, HS Oh, JE Rutledge, EB Dammer, NT Seyfried, T Wyss-Coray, O Harari, C Cruchaga	07/05/2023
Genetic background influences the 5XFAD Alzheimer's disease mouse model brain proteome. bioRxiv : the preprint server for biology	CD Hurst, AR Dunn, EB Dammer, DM Duong, NT Seyfried, CC Kaczorowski, ECB Johnson	06/13/2023
Cellular Proteomic Profiling Using Proximity Labeling by TurboID-NES in Microglial and Neuronal Cell Lines. Molecular & cellular proteomics : MCP	S Sunna, C Bowen, H Zeng, S Rayaprolu, P Kumar, P Bagchi, EB Dammer, Q Guo, DM Duong, S Bitarafan, A Natu, L Wood, NT Seyfried, S Rangaraju	06/01/2023
Multi-omic characterization of brain changes in the vascular endothelial growth factor family during aging and Alzheimer's disease. Neurobiology of aging	M Seto, L Dumitrescu, ER Mahoney, AM Sclafani, PL De Jager, V Menon, MEI Koran, RA Robinson, DM Ruderfer, NJ Cox, NT Seyfried, AL Jefferson, JA Schneider, DA Bennett, VA Petyuk, TJ Hohman	06/01/2023
Native-state proteomics of Parvalbumin interneurons identifies novel molecular signatures and metabolic vulnerabilities to early Alzheimer's disease pathology. bioRxiv : the preprint server for biology	P Kumar, AM Goettemoeller, C Espinosa-Garcia, BR Tobin, A Tfaily, RS Nelson, A Natu, EB Dammer, JV Santiago, S Malepati, L Cheng, H Xiao, D Duong, NT Seyfried, LB Wood, MJ Rowan, S Rangaraju	05/17/2023
Cross-Platform Synaptic Network Analysis of Human Entorhinal Cortex Identifies TWF2 as a Modulator of Dendritic Spine Length. The Journal of neuroscience : the official journal of the Society for Neuroscience	CK Walker, KM Greathouse, JJ Tuscher, EB Dammer, AJ Weber, E Liu, KA Curtis, BD Boros, CD Freeman, JV Seo, R Ramdas, C Hurst, DM Duong, M Gearing, CF Murchison, JJ Day, NT Seyfried, JH Herskowitz	05/17/2023
APOE expression and secretion are modulated by mitochondrial dysfunction. eLife	ME Wynne, O Ogunbona, AR Lane, A Gokhale, SA Zlatic, C Xu, Z Wen, DM Duong, S Rayaprolu, A Ivanova, EA Ortlund, EB Dammer, NT Seyfried, BR Roberts, A Crocker, V Shanbhag, M Petris, N Senoo, S Kandasamy, SM Claypool, A Barrientos, A Wingo, TS Wingo, S Rangaraju, AI Levey, E Werner, V Faundez	05/12/2023
Quantitative Mass Spectrometry Analysis of Cerebrospinal Fluid Protein Biomarkers in Alzheimer's Disease. Scientific data	CM Watson, EB Dammer, L Ping, DM Duong, E Modeste, EK Carter, ECB Johnson, AI Levey, JJ Lah, BR Roberts, NT Seyfried	05/09/2023
Integrated Proteomics to Understand the Role of Neuritin (NRN1) as a Mediator of Cognitive Resilience to Alzheimer's Disease. Molecular & cellular proteomics : MCP	C Hurst, DA Pugh, MH Abreha, DM Duong, EB Dammer, DA Bennett, JH Herskowitz, NT Seyfried	05/01/2023
Functional screening of lysosomal storage disorder genes identifies modifiers of alpha-synuclein neurotoxicity. PLoS genetics	M Yu, H Ye, RB De-Paula, CG Mangleburg, T Wu, TV Lee, Y Li, D Duong, B Phillips, C Cruchaga, GI Allen, NT Seyfried, I Al-Ramahi, J Botas, JM Shulman	05/01/2023
The landscape of metabolic brain alterations in Alzheimer's disease. Alzheimer's & dementia : the journal of the Alzheimer's Association	R Batra, M Arnold, MA Wörheide, M Allen, X Wang, C Blach, AI Levey, NT Seyfried, N Ertekin-Taner, DA Bennett, G Kastenmüller, RF Kaddurah-Daouk, J Krumsiek	03/01/2023
Proteome-Wide Discovery of Cortical Proteins That May Provide Motor Resilience to Offset the Negative Effects of Pathologies in Older Adults. The journals of gerontology. Series A, Biological sciences and medical sciences	AS Buchman, L Yu, HU Klein, AR Zammit, S Oveisgharan, F Grodstein, S Tasaki, AI Levey, NT Seyfried, DA Bennett	03/01/2023
Predictors of Cognitive Decline in Healthy Middle-Aged Individuals with Asymptomatic Alzheimer's Disease. Research square	R Tandon, L Zhao, CM Watson, M Elmor, C Heilman, K Sanders, CM Hales, H Yang, DW Loring, FC Goldstein, JJ Hanfelt, DM Duong, ECB Johnson, AP Wingo, TS Wingo, BR Roberts, NT Seyfried, AI Levey, CS Mitchell, JJ Lah	02/28/2023
INPP5D/SHIP1 regulates inflammasome activation in human microglia. bioRxiv : the preprint server for biology	V Chou, SB Fancher, RV Pearse, H Lee, M Lam, NT Seyfried, DA Bennett, PL De Jager, V Menon, TL Young-Pearse	02/26/2023
Cell-type-specific regulation of APOE levels in human neurons by the Alzheimer's disease risk gene SORL1. bioRxiv : the preprint server for biology	H Lee, AJ Aylward, RV Pearse, YC Hsieh, ZM Augur, CR Benoit, V Chou, A Knupp, C Pan, S Goberdhan, DM Duong, NT Seyfried, DA Bennett, HU Klein, PL De Jager, V Menon, JE Young, TL Young-Pearse	02/25/2023
RGS14 is neuroprotective against seizure-induced mitochondrial oxidative stress and pathology in hippocampus. bioRxiv : the preprint server for biology	NH Harbin, DJ Lustberg, C Hurst, JF Pare, KM Crotty, AL Waters, SM Yeligar, Y Smith, NT Seyfried, D Weinshenker, JR Hepler	02/03/2023
Mis-spliced transcripts generate de novo proteins in TDP-43-related ALS/FTD. bioRxiv : the preprint server for biology	S Seddighi, YA Qi, AL Brown, OG Wilkins, C Bereda, C Belair, Y Zhang, M Prudencio, MJ Keuss, A Khandeshi, S Pickles, SE Hill, J Hawrot, DM Ramos, H Yuan, J Roberts, E Kelmer Sacramento, SI Shah, MA Nalls, J Colon-Mercado, JF Reyes, VH Ryan, MP Nelson, C Cook, Z Li, L Screven, JY Kwan, A Shantaraman, L Ping, Y Koike, B Oskarsson, N Staff, DM Duong, A Ahmed, M Secrier, J Ule, S Jacobson, J Rohrer, A Malaspina, JD Glass, A Ori, NT Seyfried, M Maragkakis, L Petrucelli, P Fratta, ME Ward	01/23/2023
Bridging the rodent to human translational gap: Marmosets as model systems for the study of Alzheimer's disease. Alzheimer's & dementia (New York, N. Y.)	SJ Sukoff Rizzo, G Homanics, DJ Schaeffer, L Schaeffer, JE Park, J Oluoch, T Zhang, A Haber, NT Seyfried, B Paten, A Greenwood, T Murai, SH Choi, H Huhe, J Kofler, PL Strick, GW Carter, AC Silva	01/01/2023
Genetic background influences the 5XFAD Alzheimer's disease mouse model brain proteome. Frontiers in aging neuroscience	CD Hurst, AR Dunn, EB Dammer, DM Duong, SM Shapley, NT Seyfried, CC Kaczorowski, ECB Johnson	01/01/2023
Batch Correction and Harmonization of -Omics Datasets with a Tunable Median Polish of Ratio. Frontiers in systems biology	EB Dammer, NT Seyfried, ECB Johnson	01/01/2023
Machine Learning Selection of Most Predictive Brain Proteins Suggests Role of Sugar Metabolism in Alzheimer's Disease. Journal of Alzheimer's disease : JAD	R Tandon, AI Levey, JJ Lah, NT Seyfried, CS Mitchell	01/01/2023
Glycoproteomics Landscape of Asymptomatic and Symptomatic Human Alzheimer's Disease Brain. Molecular & cellular proteomics : MCP	S Suttapitugsakul, K Stavenhagen, S Donskaya, DA Bennett, RG Mealer, NT Seyfried, RD Cummings	12/01/2022
Multi-platform proteomic analysis of Alzheimer's disease cerebrospinal fluid and plasma reveals network biomarkers associated with proteostasis and the matrisome. Alzheimer's research & therapy	EB Dammer, L Ping, DM Duong, ES Modeste, NT Seyfried, JJ Lah, AI Levey, ECB Johnson	11/17/2022
Association of AK4 Protein From Stem Cell-Derived Neurons With Cognitive Reserve: An Autopsy Study. Neurology	L Yu, YC Hsieh, RV Pearse, Y Wang, VA Petyuk, JA Schneider, AS Buchman, NT Seyfried, PL De Jager, TL Young-Pearse, DA Bennett	11/15/2022
Interrogating the Metabolomic Profile of Amyotrophic Lateral Sclerosis in the Post-Mortem Human Brain by Infrared Matrix-Assisted Laser Desorption Electrospray Ionization (IR-MALDESI) Mass Spectrometry Imaging (MSI). Metabolites	AL Sohn, L Ping, JD Glass, NT Seyfried, EC Hector, DC Muddiman	11/10/2022
SAMHD1 deacetylation by SIRT1 promotes DNA end resection by facilitating DNA binding at double-strand breaks. Nature communications	P Kapoor-Vazirani, SK Rath, X Liu, Z Shu, NE Bowen, Y Chen, R Haji-Seyed-Javadi, W Daddacha, EV Minten, D Danelia, D Farchi, DM Duong, NT Seyfried, X Deng, EA Ortlund, B Kim, DS Yu	11/07/2022
CSF proteome profiling across the Alzheimer's disease spectrum reflects the multifactorial nature of the disease and identifies specific biomarker panels. Nature aging	M Del Campo, CFW Peeters, ECB Johnson, L Vermunt, YS Hok-A-Hin, M van Nee, A Chen-Plotkin, DJ Irwin, WT Hu, JJ Lah, NT Seyfried, EB Dammer, G Herradon, LH Meeter, J van Swieten, D Alcolea, A Lleó, AI Levey, AW Lemstra, YAL Pijnenburg, PJ Visser, BM Tijms, WM van der Flier, CE Teunissen	11/01/2022
Elevated ganglioside GM2 activator (GM2A) in human brain tissue reduces neurite integrity and spontaneous neuronal activity. Molecular neurodegeneration	YC Hsieh, J Negri, A He, RV Pearse, L Liu, DM Duong, LB Chibnik, DA Bennett, NT Seyfried, TL Young-Pearse	09/21/2022
Proximity-based labeling reveals DNA damage-induced phosphorylation of fused in sarcoma (FUS) causes distinct changes in the FUS protein interactome. The Journal of biological chemistry	MA Johnson, TA Nuckols, P Merino, P Bagchi, S Nandy, J Root, G Taylor, NT Seyfried, T Kukar	08/01/2022
Shared mechanisms across the major psychiatric and neurodegenerative diseases. Nature communications	TS Wingo, Y Liu, ES Gerasimov, SM Vattathil, ME Wynne, J Liu, A Lori, V Faundez, DA Bennett, NT Seyfried, AI Levey, AP Wingo	07/26/2022
Genetic Evidence Supporting a Causal Role of Depression in Alzheimer's Disease. Biological psychiatry	NV Harerimana, Y Liu, ES Gerasimov, D Duong, TG Beach, EM Reiman, JA Schneider, P Boyle, A Lori, DA Bennett, JJ Lah, AI Levey, NT Seyfried, TS Wingo, AP Wingo	07/01/2022
Integrating human brain proteomes with genome-wide association data implicates novel proteins in post-traumatic stress disorder. Molecular psychiatry	TS Wingo, ES Gerasimov, Y Liu, DM Duong, SM Vattathil, A Lori, J Gockley, MS Breen, AX Maihofer, CM Nievergelt, KC Koenen, DF Levey, J Gelernter, MB Stein, KJ Ressler, DA Bennett, AI Levey, NT Seyfried, AP Wingo	07/01/2022
A phase II study repurposing atomoxetine for neuroprotection in mild cognitive impairment. Brain : a journal of neurology	AI Levey, D Qiu, L Zhao, WT Hu, DM Duong, L Higginbotham, EB Dammer, NT Seyfried, TS Wingo, CM Hales, M Gámez Tansey, DS Goldstein, A Abrol, VD Calhoun, FC Goldstein, I Hajjar, AM Fagan, D Galasko, SD Edland, J Hanfelt, JJ Lah, D Weinshenker	06/30/2022
Biophysical K_v3 channel alterations dampen excitability of cortical PV interneurons and contribute to network hyperexcitability in early Alzheimer's. eLife	VJ Olah, AM Goettemoeller, S Rayaprolu, EB Dammer, NT Seyfried, S Rangaraju, J Dimidschstein, MJM Rowan	06/21/2022
Signatures of glial activity can be detected in the CSF proteome. Proceedings of the National Academy of Sciences of the United States of America	T Eninger, SA Müller, M Bacioglu, M Schweighauser, M Lambert, LF Maia, JJ Neher, SM Hornfeck, U Obermüller, G Kleinberger, C Haass, PJ Kahle, M Staufenbiel, L Ping, DM Duong, AI Levey, NT Seyfried, SF Lichtenthaler, M Jucker, SA Kaeser	06/14/2022
Cell type-specific biotin labeling in vivo resolves regional neuronal and astrocyte proteomic differences in mouse brain. Nature communications	S Rayaprolu, S Bitarafan, JV Santiago, R Betarbet, S Sunna, L Cheng, H Xiao, RS Nelson, P Kumar, P Bagchi, DM Duong, AM Goettemoeller, VJ Oláh, M Rowan, AI Levey, LB Wood, NT Seyfried, S Rangaraju	05/25/2022
Mitochondrial respiratory chain protein co-regulation in the human brain. Heliyon	C Trumpff, E Owusu-Ansah, HU Klein, AJ Lee, V Petyuk, TS Wingo, AP Wingo, M Thambisetty, L Ferrucci, NT Seyfried, DA Bennett, PL De Jager, M Picard	05/01/2022
APP and DYRK1A regulate axonal and synaptic vesicle protein networks and mediate Alzheimer's pathology in trisomy 21 neurons. Molecular psychiatry	CI Wu, EA Vinton, RV Pearse, K Heo, AJ Aylward, YC Hsieh, Y Bi, S Adeleye, S Fancher, DM Duong, NT Seyfried, TL Schwarz, TL Young-Pearse	04/01/2022
Quantitative proteomic analysis of the lysine acetylome reveals diverse SIRT2 substrates. Scientific reports	H Zhang, EB Dammer, DM Duong, D Danelia, NT Seyfried, DS Yu	03/09/2022
Neuropathologic Correlates of Human Cortical Proteins in Alzheimer Disease and Related Dementias. Neurology	L Yu, PA Boyle, AP Wingo, J Yang, T Wang, AS Buchman, TS Wingo, NT Seyfried, AI Levey, PL De Jager, JA Schneider, DA Bennett	03/08/2022
Large-scale deep multi-layer analysis of Alzheimer's disease brain reveals strong proteomic disease-related changes not observed at the RNA level. Nature neuroscience	ECB Johnson, EK Carter, EB Dammer, DM Duong, ES Gerasimov, Y Liu, J Liu, R Betarbet, L Ping, L Yin, GE Serrano, TG Beach, J Peng, PL De Jager, V Haroutunian, B Zhang, C Gaiteri, DA Bennett, M Gearing, TS Wingo, AP Wingo, JJ Lah, AI Levey, NT Seyfried	02/01/2022
Brain microRNAs are associated with variation in cognitive trajectory in advanced age. Translational psychiatry	AP Wingo, M Wang, J Liu, MS Breen, HS Yang, B Tang, JA Schneider, NT Seyfried, JJ Lah, AI Levey, DA Bennett, P Jin, PL De Jager, TS Wingo	02/01/2022
Alzheimer's disease and progressive supranuclear palsy share similar transcriptomic changes in distinct brain regions. The Journal of clinical investigation	X Wang, M Allen, Ö İş, JS Reddy, FQ Tutor-New, M Castanedes Casey, MM Carrasquillo, SR Oatman, Y Min, YW Asmann, C Funk, T Nguyen, CC Ho, KG Malphrus, NT Seyfried, AI Levey, SG Younkin, ME Murray, DW Dickson, ND Price, TE Golde, N Ertekin-Taner	01/18/2022
Exploring Cortical Proteins Underlying the Relation of Neuroticism to Cognitive Resilience. Aging brain	F Grodstein, L Yu, PL de Jager, A Levey, NT Seyfried, DA Bennett	01/01/2022
Brain Cell Type-Specific Nuclear Proteomics Is Imperative to Resolve Neurodegenerative Disease Mechanisms. Frontiers in neuroscience	RS Nelson, EB Dammer, JV Santiago, NT Seyfried, S Rangaraju	01/01/2022
Posttranslational Modifications Mediate the Structural Diversity of Tauopathy Strains. Cell	T Arakhamia, CE Lee, Y Carlomagno, M Kumar, DM Duong, H Wesseling, SR Kundinger, K Wang, D Williams, M DeTure, DW Dickson, CN Cook, NT Seyfried, L Petrucelli, JA Steen, AWP Fitzpatrick	12/09/2021
Insights into the changes in the proteome of Alzheimer disease elucidated by a meta-analysis. Scientific data	H Haytural, R Benfeitas, S Schedin-Weiss, E Bereczki, M Rezeli, RD Unwin, X Wang, EB Dammer, ECB Johnson, NT Seyfried, B Winblad, BM Tijms, PJ Visser, S Frykman, LO Tjernberg	12/03/2021
Atlas of RNA editing events affecting protein expression in aged and Alzheimer's disease human brain tissue. Nature communications	Y Ma, EB Dammer, D Felsky, DM Duong, HU Klein, CC White, M Zhou, BA Logsdon, C McCabe, J Xu, M Wang, TS Wingo, JJ Lah, B Zhang, J Schneider, M Allen, X Wang, N Ertekin-Taner, NT Seyfried, AI Levey, DA Bennett, PL De Jager	12/02/2021
Stem cell-derived neurons reflect features of protein networks, neuropathology, and cognitive outcome of their aged human donors. Neuron	VN Lagomarsino, RV Pearse, L Liu, YC Hsieh, MA Fernandez, EA Vinton, D Paull, D Felsky, S Tasaki, C Gaiteri, B Vardarajan, H Lee, CR Muratore, CR Benoit, V Chou, SB Fancher, A He, JP Merchant, DM Duong, H Martinez, M Zhou, F Bah, MA Vicent, JMS Stricker, J Xu, EB Dammer, AI Levey, LB Chibnik, V Menon, NT Seyfried, PL De Jager, S Noggle, DJ Selkoe, DA Bennett, TL Young-Pearse	11/03/2021
Orthogonal ubiquitin transfer reveals human papillomavirus E6 downregulates nuclear transport to disarm interferon-γ dependent apoptosis of cervical cancer cells. FASEB journal : official publication of the Federation of American Societies for Experimental Biology	Y Wang, R Liu, J Liao, L Jiang, GH Jeong, L Zhou, M Polite, D Duong, NT Seyfried, H Wang, H Kiyokawa, J Yin	11/01/2021
Phosphorylation regulates arginine-rich RNA-binding protein solubility and oligomerization. The Journal of biological chemistry	SR Kundinger, EB Dammer, L Yin, C Hurst, S Shapley, L Ping, S Khoshnevis, H Ghalei, DM Duong, NT Seyfried	11/01/2021
Extracellular calcium alters calcium-sensing receptor network integrating intracellular calcium-signaling and related key pathway. Scientific reports	R Gorkhali, L Tian, B Dong, P Bagchi, X Deng, S Pawar, D Duong, N Fang, N Seyfried, J Yang	10/18/2021
Association of plasma and CSF cytochrome P450, soluble epoxide hydrolase, and ethanolamide metabolism with Alzheimer's disease. Alzheimer's research & therapy	K Borkowski, TL Pedersen, NT Seyfried, JJ Lah, AI Levey, CM Hales, EB Dammer, C Blach, G Louie, R Kaddurah-Daouk, JW Newman	09/06/2021
Loss of the mitochondrial phosphate carrier SLC25A3 induces remodeling of the cardiac mitochondrial protein acylome. American journal of physiology. Cell physiology	JN Peoples, N Ghazal, DM Duong, KR Hardin, JR Manning, NT Seyfried, V Faundez, JQ Kwong	09/01/2021
Mitochondrial Proteostasis Requires Genes Encoded in a Neurodevelopmental Syndrome Locus. The Journal of neuroscience : the official journal of the Society for Neuroscience	A Gokhale, CE Lee, SA Zlatic, AAH Freeman, N Shearing, C Hartwig, O Ogunbona, JL Bassell, ME Wynne, E Werner, C Xu, Z Wen, D Duong, NT Seyfried, CE Bearden, VJ Oláh, MJM Rowan, JR Glausier, DA Lewis, V Faundez	08/04/2021
Omics sciences for systems biology in Alzheimer's disease: State-of-the-art of the evidence. Ageing research reviews	H Hampel, R Nisticò, NT Seyfried, AI Levey, E Modeste, P Lemercier, F Baldacci, N Toschi, F Garaci, G Perry, E Emanuele, PL Valenzuela, A Lucia, A Urbani, GM Sancesario, M Mapstone, M Corbo, A Vergallo, S Lista	08/01/2021
A proteomic network approach resolves stage-specific molecular phenotypes in chronic traumatic encephalopathy. Molecular neurodegeneration	L Gutierrez-Quiceno, EB Dammer, AG Johnson, JA Webster, R Shah, D Duong, L Yin, NT Seyfried, VE Alvarez, TD Stein, AC McKee, CM Hales	06/25/2021
Integrative functional genomic analysis of intron retention in human and mouse brain with Alzheimer's disease. Alzheimer's & dementia : the journal of the Alzheimer's Association	HD Li, CC Funk, K McFarland, EB Dammer, M Allen, MM Carrasquillo, Y Levites, P Chakrabarty, JD Burgess, X Wang, D Dickson, NT Seyfried, DM Duong, JJ Lah, SG Younkin, AI Levey, GS Omenn, N Ertekin-Taner, TE Golde, ND Price	06/01/2021
Extracellular signal-regulated kinase regulates microglial immune responses in Alzheimer's disease. Journal of neuroscience research	MJ Chen, S Ramesha, LD Weinstock, T Gao, L Ping, H Xiao, EB Dammer, DD Duong, AI Levey, JJ Lah, NT Seyfried, LB Wood, S Rangaraju	06/01/2021
Brain proteome-wide association study implicates novel proteins in depression pathogenesis. Nature neuroscience	TS Wingo, Y Liu, ES Gerasimov, J Gockley, BA Logsdon, DM Duong, EB Dammer, A Lori, PJ Kim, KJ Ressler, TG Beach, EM Reiman, MP Epstein, PL De Jager, JJ Lah, DA Bennett, NT Seyfried, AI Levey, AP Wingo	06/01/2021
A Genetic Study of Cerebral Atherosclerosis Reveals Novel Associations with NTNG1 and CNOT3. Genes	SM Vattathil, Y Liu, NV Harerimana, A Lori, ES Gerasimov, TG Beach, EM Reiman, PL De Jager, JA Schneider, DA Bennett, NT Seyfried, AI Levey, AP Wingo, TS Wingo	05/26/2021
A network approach reveals driver genes associated with survival of patients with triple-negative breast cancer. iScience	CD Dill, EB Dammer, TL Griffen, NT Seyfried, JW Lillard	05/21/2021
Correction to: Exploring the potential of the platelet membrane proteome as a source of peripheral biomarkers for Alzheimer's disease. Alzheimer's research & therapy	LE Donovan, EB Dammer, DM Duong, JJ Hanfelt, AI Levey, NT Seyfried, JJ Lah	05/18/2021
Unique molecular characteristics and microglial origin of Kv1.3 channel-positive brain myeloid cells in Alzheimer's disease. Proceedings of the National Academy of Sciences of the United States of America	S Ramesha, S Rayaprolu, CA Bowen, CR Giver, S Bitarafan, HM Nguyen, T Gao, MJ Chen, N Nwabueze, EB Dammer, AK Engstrom, H Xiao, A Pennati, NT Seyfried, DJ Katz, J Galipeau, H Wulff, EK Waller, LB Wood, AI Levey, S Rangaraju	03/16/2021
Genetic control of the human brain proteome. American journal of human genetics	C Robins, Y Liu, W Fan, DM Duong, J Meigs, NV Harerimana, ES Gerasimov, EB Dammer, DJ Cutler, TG Beach, EM Reiman, PL De Jager, DA Bennett, JJ Lah, AP Wingo, AI Levey, NT Seyfried, TS Wingo	03/04/2021
Integrating human brain proteomes with genome-wide association data implicates new proteins in Alzheimer's disease pathogenesis. Nature genetics	AP Wingo, Y Liu, ES Gerasimov, J Gockley, BA Logsdon, DM Duong, EB Dammer, C Robins, TG Beach, EM Reiman, MP Epstein, PL De Jager, JJ Lah, DA Bennett, NT Seyfried, AI Levey, TS Wingo	02/01/2021
Broad Kinase Inhibition Mitigates Early Neuronal Dysfunction in Tauopathy. International journal of molecular sciences	SA Koren, MJ Hamm, R Cloyd, SN Fontaine, E Chishti, C Lanzillotta, J Rodriguez-Rivera, A Ingram, M Bell, SM Galvis-Escobar, N Zulia, F Di Domenico, D Duong, NT Seyfried, D Powell, M Vandsburger, T Frolinger, AMS Hartz, J Koren, JM Axten, NJ Laping, JF Abisambra	01/26/2021
Targeted Quantification of Detergent-Insoluble RNA-Binding Proteins in Human Brain Reveals Stage and Disease Specific Co-aggregation in Alzheimer's Disease. Frontiers in molecular neuroscience	Q Guo, EB Dammer, M Zhou, SR Kundinger, M Gearing, JJ Lah, AI Levey, JM Shulman, NT Seyfried	01/01/2021
Systems-based proteomics to resolve the biology of Alzheimer's disease beyond amyloid and tau. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology	S Rayaprolu, L Higginbotham, P Bagchi, CM Watson, T Zhang, AI Levey, S Rangaraju, NT Seyfried	01/01/2021
TBK1 interacts with tau and enhances neurodegeneration in tauopathy. The Journal of biological chemistry	MH Abreha, S Ojelade, EB Dammer, ZT McEachin, DM Duong, M Gearing, GJ Bassell, JJ Lah, AI Levey, JM Shulman, NT Seyfried	01/01/2021
Cortical Proteins Associated With Cognitive Resilience in Community-Dwelling Older Persons. JAMA psychiatry	L Yu, S Tasaki, JA Schneider, K Arfanakis, DM Duong, AP Wingo, TS Wingo, N Kearns, GRJ Thatcher, NT Seyfried, AI Levey, PL De Jager, DA Bennett	11/01/2020
Network analysis of the progranulin-deficient mouse brain proteome reveals pathogenic mechanisms shared in human frontotemporal dementia caused by GRN mutations. Acta neuropathologica communications	M Huang, E Modeste, E Dammer, P Merino, G Taylor, DM Duong, Q Deng, CJ Holler, M Gearing, D Dickson, NT Seyfried, T Kukar	10/07/2020
Integrated analysis of the aging brain transcriptome and proteome in tauopathy. Molecular neurodegeneration	CG Mangleburg, T Wu, HK Yalamanchili, C Guo, YC Hsieh, DM Duong, EB Dammer, PL De Jager, NT Seyfried, Z Liu, JM Shulman	09/29/2020
Global quantitative analysis of the human brain proteome and phosphoproteome in Alzheimer's disease. Scientific data	L Ping, SR Kundinger, DM Duong, L Yin, M Gearing, JJ Lah, AI Levey, NT Seyfried	09/28/2020
Multiscale causal networks identify VGF as a key regulator of Alzheimer's disease. Nature communications	ND Beckmann, WJ Lin, M Wang, AT Cohain, AW Charney, P Wang, W Ma, YC Wang, C Jiang, M Audrain, PH Comella, AK Fakira, SP Hariharan, GM Belbin, K Girdhar, AI Levey, NT Seyfried, EB Dammer, D Duong, JJ Lah, JV Haure-Mirande, B Shackleton, T Fanutza, R Blitzer, E Kenny, J Zhu, V Haroutunian, P Katsel, S Gandy, Z Tu, ME Ehrlich, B Zhang, SR Salton, EE Schadt	08/07/2020
Publisher Correction: Shared proteomic effects of cerebral atherosclerosis and Alzheimer's disease on the human brain. Nature neuroscience	AP Wingo, W Fan, DM Duong, ES Gerasimov, EB Dammer, Y Liu, NV Harerimana, B White, M Thambisetty, JC Troncoso, N Kim, JA Schneider, IM Hajjar, JJ Lah, DA Bennett, NT Seyfried, AI Levey, TS Wingo	08/01/2020
Proteomic Analysis of Human Immune Responses to Live-Attenuated Tularemia Vaccine. Vaccines	YH Chang, DM Duong, JB Goll, DC Wood, TL Jensen, L Yin, CE Gelber, NT Seyfried, E Anderson, MS Natrajan, N Rouphael, RA Johnson, P Sanz, MJ Mulligan, DF Hoft	07/24/2020
Identification of Conserved Proteomic Networks in Neurodegenerative Dementia. Cell reports	V Swarup, TS Chang, DM Duong, EB Dammer, J Dai, JJ Lah, ECB Johnson, NT Seyfried, AI Levey, DH Geschwind	06/23/2020
Shared proteomic effects of cerebral atherosclerosis and Alzheimer's disease on the human brain. Nature neuroscience	AP Wingo, W Fan, DM Duong, ES Gerasimov, EB Dammer, Y Liu, NV Harerimana, B White, M Thambisetty, JC Troncoso, N Kim, JA Schneider, IM Hajjar, JJ Lah, DA Bennett, NT Seyfried, AI Levey, TS Wingo	06/01/2020
EZH2 has a non-catalytic and PRC2-independent role in stabilizing DDB2 to promote nucleotide excision repair. Oncogene	AE Koyen, MZ Madden, D Park, EV Minten, P Kapoor-Vazirani, E Werner, NT Pfister, R Haji-Seyed-Javadi, H Zhang, J Xu, N Deng, DM Duong, TJ Pecen, Z Frazier, ZD Nagel, JB Lazaro, KW Mouw, NT Seyfried, CS Moreno, TK Owonikoko, X Deng, DS Yu	06/01/2020
Flow-cytometric microglial sorting coupled with quantitative proteomics identifies moesin as a highly-abundant microglial protein with relevance to Alzheimer's disease. Molecular neurodegeneration	S Rayaprolu, T Gao, H Xiao, S Ramesha, LD Weinstock, J Shah, DM Duong, EB Dammer, JA Webster, JJ Lah, LB Wood, R Betarbet, AI Levey, NT Seyfried, S Rangaraju	05/07/2020
Large-scale proteomic analysis of Alzheimer's disease brain and cerebrospinal fluid reveals early changes in energy metabolism associated with microglia and astrocyte activation. Nature medicine	ECB Johnson, EB Dammer, DM Duong, L Ping, M Zhou, L Yin, LA Higginbotham, A Guajardo, B White, JC Troncoso, M Thambisetty, TJ Montine, EB Lee, JQ Trojanowski, TG Beach, EM Reiman, V Haroutunian, M Wang, E Schadt, B Zhang, DW Dickson, N Ertekin-Taner, TE Golde, VA Petyuk, PL De Jager, DA Bennett, TS Wingo, S Rangaraju, I Hajjar, JM Shulman, JJ Lah, AI Levey, NT Seyfried	05/01/2020
Middle-Down Proteomics Reveals Dense Sites of Methylation and Phosphorylation in Arginine-Rich RNA-Binding Proteins. Journal of proteome research	SR Kundinger, I Bishof, EB Dammer, DM Duong, NT Seyfried	04/03/2020
Posttranslational Modifications Mediate the Structural Diversity of Tauopathy Strains. Cell	T Arakhamia, CE Lee, Y Carlomagno, DM Duong, SR Kundinger, K Wang, D Williams, M DeTure, DW Dickson, CN Cook, NT Seyfried, L Petrucelli, AWP Fitzpatrick	02/20/2020
Quantitative Proteomics Reveal an Altered Pattern of Protein Expression in Brain Tissue from Mice Lacking GPR37 and GPR37L1. Journal of proteome research	TT Nguyen, EB Dammer, SA Owino, MM Giddens, NS Madaras, DM Duong, NT Seyfried, RA Hall	02/07/2020
Translational animal models for Alzheimer's disease: An Alzheimer's Association Business Consortium Think Tank. Alzheimer's & dementia (New York, N. Y.)	MP Vitek, JA Araujo, M Fossel, BD Greenberg, GR Howell, SJS Rizzo, NT Seyfried, AJ Tenner, PR Territo, M Windisch, LJ Bain, A Ross, MC Carrillo, BT Lamb, RM Edelmayer	01/01/2020
Targeted mass spectrometry to quantify brain-derived cerebrospinal fluid biomarkers in Alzheimer's disease. Clinical proteomics	M Zhou, RU Haque, EB Dammer, DM Duong, L Ping, ECB Johnson, JJ Lah, AI Levey, NT Seyfried	01/01/2020
Molecular Signatures of Neuroinflammation Induced by αSynuclein Aggregates in Microglial Cells. Frontiers in immunology	S Sarkar, EB Dammer, E Malovic, AL Olsen, SA Raza, T Gao, H Xiao, DL Oliver, D Duong, V Joers, N Seyfried, M Huang, T Kukar, MG Tansey, AG Kanthasamy, S Rangaraju	01/01/2020
Brain microRNAs associated with late-life depressive symptoms are also associated with cognitive trajectory and dementia. NPJ genomic medicine	TS Wingo, J Yang, W Fan, S Min Canon, ES Gerasimov, A Lori, B Logsdon, B Yao, NT Seyfried, JJ Lah, AI Levey, PA Boyle, JA Schneider, PL De Jager, DA Bennett, AP Wingo	01/01/2020
Tau-Mediated Disruption of the Spliceosome Triggers Cryptic RNA Splicing and Neurodegeneration in Alzheimer's Disease. Cell reports	YC Hsieh, C Guo, HK Yalamanchili, M Abreha, R Al-Ouran, Y Li, EB Dammer, JJ Lah, AI Levey, DA Bennett, PL De Jager, NT Seyfried, Z Liu, JM Shulman	10/08/2019
Transcriptional regulation of homeostatic and disease-associated-microglial genes by IRF1, LXRβ, and CEBPα. Glia	T Gao, J Jernigan, SA Raza, EB Dammer, H Xiao, NT Seyfried, AI Levey, S Rangaraju	10/01/2019
Ionizing Radiation induction of cholesterol biosynthesis in Lung tissue. Scientific reports	E Werner, A Alter, Q Deng, EB Dammer, Y Wang, DS Yu, DM Duong, NT Seyfried, PW Doetsch	08/29/2019
Network Analysis of a Membrane-Enriched Brain Proteome across Stages of Alzheimer's Disease. Proteomes	L Higginbotham, EB Dammer, DM Duong, E Modeste, TJ Montine, JJ Lah, AI Levey, NT Seyfried	08/27/2019
Mass Spectrometry-Based Quantification of Tau in Human Cerebrospinal Fluid Using a Complementary Tryptic Peptide Standard. Journal of proteome research	M Zhou, DM Duong, ECB Johnson, J Dai, JJ Lah, AI Levey, NT Seyfried	06/07/2019
Specific Proteomes of Hippocampal Regions CA2 and CA1 Reveal Proteins Linked to the Unique Physiology of Area CA2. Journal of proteome research	KJ Gerber, EB Dammer, DM Duong, Q Deng, SM Dudek, NT Seyfried, JR Hepler	06/07/2019
Proteomic analysis reveals that wildtype and alanine-expanded nuclear poly(A)-binding protein exhibit differential interactions in skeletal muscle. The Journal of biological chemistry	A Banerjee, BL Phillips, Q Deng, NT Seyfried, GK Pavlath, KE Vest, AH Corbett	05/03/2019
Systems Analysis of the 22q11.2 Microdeletion Syndrome Converges on a Mitochondrial Interactome Necessary for Synapse Function and Behavior. The Journal of neuroscience : the official journal of the Society for Neuroscience	A Gokhale, C Hartwig, AAH Freeman, JL Bassell, SA Zlatic, C Sapp Savas, T Vadlamudi, F Abudulai, TT Pham, A Crocker, E Werner, Z Wen, GM Repetto, JA Gogos, SM Claypool, JK Forsyth, CE Bearden, J Glausier, DA Lewis, NT Seyfried, JQ Kwong, V Faundez	05/01/2019
Large-scale proteomic analysis of human brain identifies proteins associated with cognitive trajectory in advanced age. Nature communications	AP Wingo, EB Dammer, MS Breen, BA Logsdon, DM Duong, JC Troncosco, M Thambisetty, TG Beach, GE Serrano, EM Reiman, RJ Caselli, JJ Lah, NT Seyfried, AI Levey, TS Wingo	04/08/2019
Identification of evolutionarily conserved gene networks mediating neurodegenerative dementia. Nature medicine	V Swarup, FI Hinz, JE Rexach, KI Noguchi, H Toyoshiba, A Oda, K Hirai, A Sarkar, NT Seyfried, C Cheng, SJ Haggarty, M Grossman, VM Van Deerlin, JQ Trojanowski, JJ Lah, AI Levey, S Kondou, DH Geschwind	01/01/2019
Convergence of independent DISC1 mutations on impaired neurite growth via decreased UNC5D expression. Translational psychiatry	P Srikanth, VN Lagomarsino, RV Pearse, M Liao, S Ghosh, R Nehme, N Seyfried, K Eggan, TL Young-Pearse	11/08/2018
Deep proteomic network analysis of Alzheimer's disease brain reveals alterations in RNA binding proteins and RNA splicing associated with disease. Molecular neurodegeneration	ECB Johnson, EB Dammer, DM Duong, L Yin, M Thambisetty, JC Troncoso, JJ Lah, AI Levey, NT Seyfried	10/04/2018
Quantitative Analysis of the Brain Ubiquitylome in Alzheimer's Disease. Proteomics	MH Abreha, EB Dammer, L Ping, T Zhang, DM Duong, M Gearing, JJ Lah, AI Levey, NT Seyfried	10/01/2018
The Mount Sinai cohort of large-scale genomic, transcriptomic and proteomic data in Alzheimer's disease. Scientific data	M Wang, ND Beckmann, P Roussos, E Wang, X Zhou, Q Wang, C Ming, R Neff, W Ma, JF Fullard, ME Hauberg, J Bendl, MA Peters, B Logsdon, P Wang, M Mahajan, LM Mangravite, EB Dammer, DM Duong, JJ Lah, NT Seyfried, AI Levey, JD Buxbaum, M Ehrlich, S Gandy, P Katsel, V Haroutunian, E Schadt, B Zhang	09/11/2018
RNA-binding proteins with basic-acidic dipeptide (BAD) domains self-assemble and aggregate in Alzheimer's disease. The Journal of biological chemistry	I Bishof, EB Dammer, DM Duong, SR Kundinger, M Gearing, JJ Lah, AI Levey, NT Seyfried	07/13/2018
Quantitative proteomics of acutely-isolated mouse microglia identifies novel immune Alzheimer's disease-related proteins. Molecular neurodegeneration	S Rangaraju, EB Dammer, SA Raza, T Gao, H Xiao, R Betarbet, DM Duong, JA Webster, CM Hales, JJ Lah, AI Levey, NT Seyfried	06/28/2018
Identification and therapeutic modulation of a pro-inflammatory subset of disease-associated-microglia in Alzheimer's disease. Molecular neurodegeneration	S Rangaraju, EB Dammer, SA Raza, P Rathakrishnan, H Xiao, T Gao, DM Duong, MW Pennington, JJ Lah, NT Seyfried, AI Levey	05/21/2018
Interactome Analysis Reveals Regulator of G Protein Signaling 14 (RGS14) is a Novel Calcium/Calmodulin (Ca²⁺/CaM) and CaM Kinase II (CaMKII) Binding Partner. Journal of proteome research	PR Evans, KJ Gerber, EB Dammer, DM Duong, D Goswami, DJ Lustberg, J Zou, JJ Yang, SM Dudek, PR Griffin, NT Seyfried, JR Hepler	04/06/2018
Global quantitative analysis of the human brain proteome in Alzheimer's and Parkinson's Disease. Scientific data	L Ping, DM Duong, L Yin, M Gearing, JJ Lah, AI Levey, NT Seyfried	03/13/2018
Conserved brain myelination networks are altered in Alzheimer's and other neurodegenerative diseases. Alzheimer's & dementia : the journal of the Alzheimer's Association	M Allen, X Wang, JD Burgess, J Watzlawik, DJ Serie, CS Younkin, T Nguyen, KG Malphrus, S Lincoln, MM Carrasquillo, C Ho, P Chakrabarty, S Strickland, ME Murray, V Swarup, DH Geschwind, NT Seyfried, EB Dammer, JJ Lah, AI Levey, TE Golde, C Funk, H Li, ND Price, RC Petersen, NR Graff-Radford, SG Younkin, DW Dickson, JR Crook, YW Asmann, N Ertekin-Taner	03/01/2018
Evidence for brain glucose dysregulation in Alzheimer's disease. Alzheimer's & dementia : the journal of the Alzheimer's Association	Y An, VR Varma, S Varma, R Casanova, E Dammer, O Pletnikova, CW Chia, JM Egan, L Ferrucci, J Troncoso, AI Levey, J Lah, NT Seyfried, C Legido-Quigley, R O'Brien, M Thambisetty	03/01/2018
TDP-43 pathology disrupts nuclear pore complexes and nucleocytoplasmic transport in ALS/FTD. Nature neuroscience	CC Chou, Y Zhang, ME Umoh, SW Vaughan, I Lorenzini, F Liu, M Sayegh, PG Donlin-Asp, YH Chen, DM Duong, NT Seyfried, MA Powers, T Kukar, CM Hales, M Gearing, NJ Cairns, KB Boylan, DW Dickson, R Rademakers, YJ Zhang, L Petrucelli, R Sattler, DC Zarnescu, JD Glass, W Rossoll	02/01/2018
A proteomic network approach across the ALS-FTD disease spectrum resolves clinical phenotypes and genetic vulnerability in human brain. EMBO molecular medicine	ME Umoh, EB Dammer, J Dai, DM Duong, JJ Lah, AI Levey, M Gearing, JD Glass, NT Seyfried	01/01/2018
Differential Phagocytic Properties of CD45^low Microglia and CD45^high Brain Mononuclear Phagocytes-Activation and Age-Related Effects. Frontiers in immunology	S Rangaraju, SA Raza, NX Li, R Betarbet, EB Dammer, D Duong, JJ Lah, NT Seyfried, AI Levey	01/01/2018
Effects of APOE Genotype on Brain Proteomic Network and Cell Type Changes in Alzheimer's Disease. Frontiers in molecular neuroscience	J Dai, ECB Johnson, EB Dammer, DM Duong, M Gearing, JJ Lah, AI Levey, TS Wingo, NT Seyfried	01/01/2018
Characterization of Detergent Insoluble Proteome in Chronic Traumatic Encephalopathy. Journal of neuropathology and experimental neurology	JD Cherry, A Zeineddin, EB Dammer, JA Webster, D Duong, NT Seyfried, AI Levey, VE Alvarez, BR Huber, TD Stein, PT Kiernan, AC McKee, JJ Lah, CM Hales	01/01/2018
Identifying the substrate proteins of U-box E3s E4B and CHIP by orthogonal ubiquitin transfer. Science advances	K Bhuripanyo, Y Wang, X Liu, L Zhou, R Liu, D Duong, B Zhao, Y Bi, H Zhou, G Chen, NT Seyfried, WJ Chazin, H Kiyokawa, J Yin	01/01/2018
Multiscale network modeling of oligodendrocytes reveals molecular components of myelin dysregulation in Alzheimer's disease. Molecular neurodegeneration	AT McKenzie, S Moyon, M Wang, I Katsyv, WM Song, X Zhou, EB Dammer, DM Duong, J Aaker, Y Zhao, N Beckmann, P Wang, J Zhu, JJ Lah, NT Seyfried, AI Levey, P Katsel, V Haroutunian, EE Schadt, B Popko, P Casaccia, B Zhang	11/06/2017
Enrichment of Detergent-insoluble Protein Aggregates from Human Postmortem Brain. Journal of visualized experiments : JoVE	I Diner, T Nguyen, NT Seyfried	10/24/2017
Generation of Clickable Pittsburgh Compound B for the Detection and Capture of β-Amyloid in Alzheimer's Disease Brain. Bioconjugate chemistry	I Diner, J Dooyema, M Gearing, LC Walker, NT Seyfried	10/18/2017
The RNA-binding protein, ZC3H14, is required for proper poly(A) tail length control, expression of synaptic proteins, and brain function in mice. Human molecular genetics	J Rha, SK Jones, J Fidler, A Banerjee, SW Leung, KJ Morris, JC Wong, GAS Inglis, L Shapiro, Q Deng, AA Cutler, AM Hanif, MT Pardue, A Schaffer, NT Seyfried, KH Moberg, GJ Bassell, A Escayg, PS García, AH Corbett	10/01/2017
Integrating Next-Generation Genomic Sequencing and Mass Spectrometry To Estimate Allele-Specific Protein Abundance in Human Brain. Journal of proteome research	TS Wingo, DM Duong, M Zhou, EB Dammer, H Wu, DJ Cutler, JJ Lah, AI Levey, NT Seyfried	09/01/2017
Biochemical isolation of myonuclei employed to define changes to the myonuclear proteome that occur with aging. Aging cell	AA Cutler, EB Dammer, DM Doung, NT Seyfried, AH Corbett, GK Pavlath	08/01/2017
Asparagine endopeptidase cleaves α-synuclein and mediates pathologic activities in Parkinson's disease. Nature structural & molecular biology	Z Zhang, SS Kang, X Liu, EH Ahn, Z Zhang, L He, PM Iuvone, DM Duong, NT Seyfried, MJ Benskey, FP Manfredsson, L Jin, YE Sun, JZ Wang, K Ye	08/01/2017
Biochemical characterization of purified mammalian ARL13B protein indicates that it is an atypical GTPase and ARL3 guanine nucleotide exchange factor (GEF). The Journal of biological chemistry	AA Ivanova, T Caspary, NT Seyfried, DM Duong, AB West, Z Liu, RA Kahn	06/30/2017
A systems pharmacology-based approach to identify novel Kv1.3 channel-dependent mechanisms in microglial activation. Journal of neuroinflammation	S Rangaraju, SA Raza, A Pennati, Q Deng, EB Dammer, D Duong, MW Pennington, MG Tansey, JJ Lah, R Betarbet, NT Seyfried, AI Levey	06/26/2017
A Multi-network Approach Identifies Protein-Specific Co-expression in Asymptomatic and Symptomatic Alzheimer's Disease. Cell systems	NT Seyfried, EB Dammer, V Swarup, D Nandakumar, DM Duong, L Yin, Q Deng, T Nguyen, CM Hales, T Wingo, J Glass, M Gearing, M Thambisetty, JC Troncoso, DH Geschwind, JJ Lah, AI Levey	01/25/2017
The State of Systems Genetics in 2017. Cell systems	NS Baliga, JL Björkegren, JD Boeke, M Boutros, NP Crawford, AM Dudley, CR Farber, A Jones, AI Levey, AJ Lusis, HC Mak, JH Nadeau, MB Noyes, E Petretto, NT Seyfried, LM Steinmetz, SC Vonesch	01/25/2017
Osteopontin Is a Blood Biomarker for Microglial Activation and Brain Injury in Experimental Hypoxic-Ischemic Encephalopathy. eNeuro	Y Li, EB Dammer, X Zhang-Brotzge, S Chen, DM Duong, NT Seyfried, CY Kuan, YY Sun	01/01/2017
Changes in the detergent-insoluble brain proteome linked to amyloid and tau in Alzheimer's Disease progression. Proteomics	CM Hales, EB Dammer, Q Deng, DM Duong, M Gearing, JC Troncoso, M Thambisetty, JJ Lah, JM Shulman, AI Levey, NT Seyfried	12/01/2016
The Evolutionarily-conserved Polyadenosine RNA Binding Protein, Nab2, Cooperates with Splicing Machinery to Regulate the Fate of pre-mRNA. Molecular and cellular biology	S Soucek, Y Zeng, DL Bellur, M Bergkessel, KJ Morris, Q Deng, D Duong, NT Seyfried, C Guthrie, JP Staley, MB Fasken, AH Corbett	11/01/2016
CSF complement 3 and factor H are staging biomarkers in Alzheimer's disease. Acta neuropathologica communications	WT Hu, KD Watts, P Tailor, TP Nguyen, JC Howell, RC Lee, NT Seyfried, M Gearing, CM Hales, AI Levey, JJ Lah, EK Lee	02/17/2016
ATRIP Deacetylation by SIRT2 Drives ATR Checkpoint Activation by Promoting Binding to RPA-ssDNA. Cell reports	H Zhang, PE Head, W Daddacha, SH Park, X Li, Y Pan, MZ Madden, DM Duong, M Xie, B Yu, MD Warren, EA Liu, VR Dhere, C Li, I Pradilla, MA Torres, Y Wang, WS Dynan, PW Doetsch, X Deng, NT Seyfried, D Gius, DS Yu	02/16/2016
Pseudomonas aeruginosa EftM Is a Thermoregulated Methyltransferase. The Journal of biological chemistry	JP Owings, EG Kuiper, SM Prezioso, J Meisner, JJ Varga, N Zelinskaya, EB Dammer, DM Duong, NT Seyfried, S Albertí, GL Conn, JB Goldberg	02/12/2016
FUS is phosphorylated by DNA-PK and accumulates in the cytoplasm after DNA damage. The Journal of neuroscience : the official journal of the Society for Neuroscience	Q Deng, CJ Holler, G Taylor, KF Hudson, W Watkins, M Gearing, D Ito, ME Murray, DW Dickson, NT Seyfried, T Kukar	06/04/2014
Pharmacologic inhibition of ROCK2 suppresses amyloid-β production in an Alzheimer's disease mouse model. The Journal of neuroscience : the official journal of the Society for Neuroscience	JH Herskowitz, Y Feng, AL Mattheyses, CM Hales, LA Higginbotham, DM Duong, TJ Montine, JC Troncoso, M Thambisetty, NT Seyfried, AI Levey, JJ Lah	12/04/2013
U1 small nuclear ribonucleoprotein complex and RNA splicing alterations in Alzheimer's disease. Proceedings of the National Academy of Sciences of the United States of America	B Bai, CM Hales, PC Chen, Y Gozal, EB Dammer, JJ Fritz, X Wang, Q Xia, DM Duong, C Street, G Cantero, D Cheng, DR Jones, Z Wu, Y Li, I Diner, CJ Heilman, HD Rees, H Wu, L Lin, KE Szulwach, M Gearing, EJ Mufson, DA Bennett, TJ Montine, NT Seyfried, TS Wingo, YE Sun, P Jin, J Hanfelt, DM Willcock, A Levey, JJ Lah, J Peng	10/08/2013