Hyunsuk Shim, PhD

Research Program

Discovery and Developmental Therapeutics
Phone Number

404-778-4564
Email Address

hshim@emory.edu

Biography

Hyunsuk Shim, PhD, is professor and Crocker Family Chair in Cancer Innovation and serves as Promotions Committee Director in the Department of Radiation Oncology at Emory University School of Medicine. Dr. Shim has emerged as one of Georgia's most promising biomedical researchers and has been recognized as a Georgia Cancer Coalition Distinguished Scholar and a member of the Council of Distinguished Investigators of the Academy of Radiology Research. She leads Emory University's NCI Quantitative Imaging Network team, which is working on groundbreaking research on glioblastoma using high resolution/high speed volumetric spectroscopic MRI.

Dr. Shim is a member of the Discovery and Developmental Therapeutics Research Program at Winship Cancer Institute.

Education

Dr. Shim received her PhD from University of Illinois at Urbana-Champaign in Urbana, IL.

Titles & Roles

Professor and Crocker Family Chair in Cancer Innovation, Department of Radiation Oncology

Emory University School of Medicine
Director, Promotions Committee, Department of Radiation Oncology

Emory University School of Medicine

Research

Dr. Shim's brain imaging team has developed an advanced MRSI technique combined with a multi-modality imaging platform to assess how glioblastomas are responding to therapies by quantitatively measuring metabolic processes. In addition, she leads the technical development of 3D whole-brain spectroscopic MRI to guide high dose radiation therapy for brain tumors.

Publications

Title/Journal	Authors	Publication Date
The Utility of Spectroscopic MRI in Stereotactic Biopsy and Radiotherapy Guidance in Newly Diagnosed Glioblastoma. Tomography (Ann Arbor, Mich.)	AC Rejimon, KK Ramesh, AG Trivedi, V Huang, E Schreibmann, BD Weinberg, LR Kleinberg, HG Shu, H Shim, JJ Olson	03/20/2024
SPECTRO GLIO trial aftermath: Where do we go from here? Neuro-oncology	HG Shu, H Shim	01/05/2024
Corrigendum to "Synthesis and evaluation of 2,5-furan, 2,5-thiophene and 3,4-thiophene-based derivatives as CXCR4 inhibitors" [Eur. J. Med. Chem. 181 (2019) 111562]. European journal of medicinal chemistry	T Gaines, F Garcia, S Virani, Z Liang, Y Yoon, YH Oum, H Shim, SR Mooring	12/05/2023
A Fully Automated Post-Surgical Brain Tumor Segmentation Model for Radiation Treatment Planning and Longitudinal Tracking. Cancers	KK Ramesh, KM Xu, AG Trivedi, V Huang, VK Sharghi, LR Kleinberg, EA Mellon, HG Shu, H Shim, BD Weinberg	08/03/2023
Spectroscopic MRI-Based Biomarkers Predict Survival for Newly Diagnosed Glioblastoma in a Clinical Trial. Cancers	AG Trivedi, KK Ramesh, V Huang, EA Mellon, PB Barker, LR Kleinberg, BD Weinberg, HG Shu, H Shim	07/07/2023
Applying a Radiation Therapy Volume Analysis Pipeline to Determine the Utility of Spectroscopic MRI-Guided Adaptive Radiation Therapy for Glioblastoma. Tomography (Ann Arbor, Mich.)	AG Trivedi, SH Kim, KK Ramesh, AS Giuffrida, BD Weinberg, EA Mellon, LR Kleinberg, PB Barker, H Han, HG Shu, H Shim, E Schreibmann	05/21/2023
Mutant Isocitrate Dehydrogenase 1 Expression Enhances Response of Gliomas to the Histone Deacetylase Inhibitor Belinostat. Tomography (Ann Arbor, Mich.)	CM Chang, KK Ramesh, V Huang, S Gurbani, LR Kleinberg, BD Weinberg, H Shim, HG Shu	05/04/2023
Mapping early tumor response to radiotherapy using diffusion kurtosis imaging*. The neuroradiology journal	M Goryawala, EA Mellon, H Shim, AA Maudsley	04/01/2023
Spectroscopic MRI-Guided Proton Therapy in Non-Enhancing Pediatric High-Grade Glioma. Tomography (Ann Arbor, Mich.)	V Huang, A Rejimon, K Reddy, AG Trivedi, KK Ramesh, AS Giuffrida, R Muiruri, H Shim, BR Eaton	03/09/2023
A Novel Approach to Determining Tumor Progression Using a Three-Site Pilot Clinical Trial of Spectroscopic MRI-Guided Radiation Dose Escalation in Glioblastoma. Tomography (Ann Arbor, Mich.)	KK Ramesh, V Huang, J Rosenthal, EA Mellon, M Goryawala, PB Barker, SS Gurbani, AG Trivedi, AS Giuffrida, E Schreibmann, H Han, M de le Fuente, EM Dunbar, M Holdhoff, LR Kleinberg, HG Shu, H Shim, BD Weinberg	02/06/2023
Final Report on Clinical Outcomes and Tumor Recurrence Patterns of a Pilot Study Assessing Efficacy of Belinostat (PXD-101) with Chemoradiation for Newly Diagnosed Glioblastoma. Tomography (Ann Arbor, Mich.)	K Xu, K Ramesh, V Huang, SS Gurbani, JS Cordova, E Schreibmann, BD Weinberg, S Sengupta, AD Voloschin, M Holdhoff, PB Barker, LR Kleinberg, JJ Olson, HG Shu, H Shim	03/03/2022
A multi-institutional pilot clinical trial of spectroscopic MRI-guided radiation dose escalation for newly diagnosed glioblastoma. Neuro-oncology advances	K Ramesh, EA Mellon, SS Gurbani, BD Weinberg, E Schreibmann, SA Sheriff, M Goryawala, M de le Fuente, BR Eaton, J Zhong, AD Voloschin, S Sengupta, EM Dunbar, M Holdhoff, PB Barker, AA Maudsley, LR Kleinberg, H Shim, HG Shu	01/01/2022
3D whole-brain metabolite imaging to improve characterization of low-to-intermediate grade gliomas. Journal of neuro-oncology	J Zhong, V Huang, SS Gurbani, K Ramesh, J Scott Cordova, E Schreibmann, HG Shu, J Olson, H Han, A Giuffrida, H Shim, BD Weinberg	06/01/2021
Clinical Applications of Magnetic Resonance Spectroscopy in Brain Tumors: From Diagnosis to Treatment. Radiologic clinics of North America	BD Weinberg, M Kuruva, H Shim, ME Mullins	05/01/2021
Discovery of novel aminopiperidinyl amide CXCR4 modulators through virtual screening and rational drug design. European journal of medicinal chemistry	YH Oum, SA Kell, Y Yoon, Z Liang, P Burger, H Shim	09/01/2020
The Longitudinal Imaging Tracker (BrICS-LIT):A Cloud Platform for Monitoring Treatment Response in Glioblastoma Patients. Tomography (Ann Arbor, Mich.)	K Ramesh, SS Gurbani, EA Mellon, V Huang, M Goryawala, PB Barker, L Kleinberg, HG Shu, H Shim, BD Weinberg	06/01/2020
Remarkable response of a patient with secondary glioblastoma to a histone deacetylase inhibitor. Oxford medical case reports	SS Gurbani, BD Weinberg, E Salgado, A Voloschin, JE Velazquez Vega, JJ Olson, HG Shu, H Shim	03/01/2020
MicroRNA-30c-regulated HDAC9 mediates chemoresistance of breast cancer. Cancer chemotherapy and pharmacology	Z Liang, A Feng, H Shim	02/01/2020
A benzenesulfonamide derivative as a novel PET radioligand for CXCR4. Bioorganic & medicinal chemistry	YH Oum, D Shetty, Y Yoon, Z Liang, RJ Voll, MM Goodman, H Shim	01/15/2020
Amide-sulfamide modulators as effective anti-tumor metastatic agents targeting CXCR4/CXCL12 axis. European journal of medicinal chemistry	R Wu, W Yu, C Yao, Z Liang, Y Yoon, Y Xie, H Shim, R Bai	01/01/2020
Synthesis and evaluation of 2,5-furan, 2,5-thiophene and 3,4-thiophene-based derivatives as CXCR4 inhibitors. European journal of medicinal chemistry	T Gaines, F Garcia, S Virani, Z Liang, Y Yoon, YH Oum, H Shim, SR Mooring	11/01/2019
Presentation of treatment effect in glioblastoma after dose-escalation radiation therapy. Oxford medical case reports	D Cicka, CL Ford, E Templin, Z Pitts, S Gurbani, B Eaton, L Lowder, J Olson, BD Weinberg, H Shim, S Sengupta	09/01/2019
The Role of Standard and Advanced Imaging for the Management of Brain Malignancies From a Radiation Oncology Standpoint. Neurosurgery	RH Press, J Zhong, SS Gurbani, BD Weinberg, BR Eaton, H Shim, HG Shu	08/01/2019
Development of CXCR4 modulators based on the lead compound RB-108. European journal of medicinal chemistry	R Bai, X Jie, J Sun, Z Liang, Y Yoon, A Feng, Y Oum, W Yu, R Wu, B Sun, E Salgado, Y Xie, H Shim	07/01/2019
Incorporation of a spectral model in a convolutional neural network for accelerated spectral fitting. Magnetic resonance in medicine	SS Gurbani, S Sheriff, AA Maudsley, H Shim, LAD Cooper	05/01/2019
Assessing Treatment Response of Glioblastoma to an HDAC Inhibitor Using Whole-Brain Spectroscopic MRI. Tomography (Ann Arbor, Mich.)	SS Gurbani, Y Yoon, BD Weinberg, E Salgado, RH Press, JS Cordova, KK Ramesh, Z Liang, J Velazquez Vega, A Voloschin, JJ Olson, E Schreibmann, H Shim, HG Shu	03/01/2019
The Brain Imaging Collaboration Suite (BrICS): A Cloud Platform for Integrating Whole-Brain Spectroscopic MRI into the Radiation Therapy Planning Workflow. Tomography (Ann Arbor, Mich.)	S Gurbani, B Weinberg, L Cooper, E Mellon, E Schreibmann, S Sheriff, A Maudsley, M Goryawala, HK Shu, H Shim	03/01/2019
Synthesis and evaluation of 2,5-diamino and 2,5-dianilinomethyl pyridine analogues as potential CXCR4 antagonists. Bioorganic & medicinal chemistry letters	S Virani, Z Liang, Y Yoon, H Shim, SR Mooring	01/15/2019
MRI-based attenuation correction for brain PET/MRI based on anatomic signature and machine learning. Physics in medicine and biology	X Yang, T Wang, Y Lei, K Higgins, T Liu, H Shim, WJ Curran, H Mao, JA Nye	01/07/2019
The role of erlotinib and the Optune device in a patient with an epidermal growth factor receptor viii amplified glioblastoma. Oxford medical case reports	SP Doyle, SS Gurbani, AS Ross, H Rosen, CD Barrett, JJ Olson, H Shim, HK Shu, S Sengupta	12/01/2018
The Use of Quantitative Imaging in Radiation Oncology: A Quantitative Imaging Network (QIN) Perspective. International journal of radiation oncology, biology, physics	RH Press, HG Shu, H Shim, JM Mountz, BF Kurland, RL Wahl, EF Jones, NM Hylton, ER Gerstner, RJ Nordstrom, L Henderson, KA Kurdziel, B Vikram, MA Jacobs, M Holdhoff, E Taylor, DA Jaffray, LH Schwartz, DA Mankoff, PE Kinahan, HM Linden, P Lambin, TJ Dilling, DL Rubin, L Hadjiiski, JM Buatti	11/15/2018
A convolutional neural network to filter artifacts in spectroscopic MRI. Magnetic resonance in medicine	SS Gurbani, E Schreibmann, AA Maudsley, JS Cordova, BJ Soher, H Poptani, G Verma, PB Barker, H Shim, LAD Cooper	11/01/2018
MRI-based pseudo CT synthesis using anatomical signature and alternating random forest with iterative refinement model. Journal of medical imaging (Bellingham, Wash.)	Y Lei, JJ Jeong, T Wang, HK Shu, P Patel, S Tian, T Liu, H Shim, H Mao, AB Jani, WJ Curran, X Yang	10/01/2018
HDAC9 overexpression confers invasive and angiogenic potential to triple negative breast cancer cells via modulating microRNA-206. Biochemical and biophysical research communications	E Salgado, X Bian, A Feng, H Shim, Z Liang	09/05/2018
Magnetic resonance imaging-based pseudo computed tomography using anatomic signature and joint dictionary learning. Journal of medical imaging (Bellingham, Wash.)	Y Lei, HK Shu, S Tian, JJ Jeong, T Liu, H Shim, H Mao, T Wang, AB Jani, WJ Curran, X Yang	07/01/2018
Anti-inflammatory hybrids of secondary amines and amide-sulfamide derivatives. European journal of medicinal chemistry	R Bai, J Sun, Z Liang, Y Yoon, E Salgado, A Feng, Y Oum, Y Xie, H Shim	04/25/2018
High-resolution CT Image Retrieval Using Sparse Convolutional Neural Network. Proceedings of SPIE--the International Society for Optical Engineering	Y Lei, D Xu, Z Zhou, K Higgins, X Dong, T Liu, H Shim, H Mao, WJ Curran, X Yang	02/01/2018
Improving Image Quality of Cone-Beam CT Using Alternating Regression Forest. Proceedings of SPIE--the International Society for Optical Engineering	Y Lei, X Tang, K Higgins, T Wang, T Liu, A Dhabaan, H Shim, WJ Curran, X Yang	02/01/2018
HDAC inhibitor suppresses proliferation and invasion of breast cancer cells through regulation of miR-200c targeting CRKL. Biochemical pharmacology	X Bian, Z Liang, A Feng, E Salgado, H Shim	01/01/2018
Novel anti-inflammatory agents targeting CXCR4: Design, synthesis, biological evaluation and preliminary pharmacokinetic study. European journal of medicinal chemistry	R Bai, Z Liang, Y Yoon, E Salgado, A Feng, S Gurbani, H Shim	08/18/2017
Pseudo CT Estimation from MRI Using Patch-based Random Forest. Proceedings of SPIE--the International Society for Optical Engineering	X Yang, Y Lei, HK Shu, P Rossi, H Mao, H Shim, WJ Curran, T Liu	02/01/2017
Development of CXCR4 modulators by virtual HTS of a novel amide-sulfamide compound library. European journal of medicinal chemistry	R Bai, Q Shi, Z Liang, Y Yoon, Y Han, A Feng, S Liu, Y Oum, CC Yun, H Shim	01/27/2017
Simulating the Effect of Spectroscopic MRI as a Metric for Radiation Therapy Planning in Patients with Glioblastoma. Tomography (Ann Arbor, Mich.)	JS Cordova, S Kandula, S Gurbani, J Zhong, M Tejani, O Kayode, K Patel, R Prabhu, E Schreibmann, I Crocker, CA Holder, H Shim, HK Shu	12/01/2016
Synthesis and evaluation of 2,5 and 2,6 pyridine-based CXCR4 inhibitors. Bioorganic & medicinal chemistry	T Gaines, D Camp, R Bai, Z Liang, Y Yoon, H Shim, SR Mooring	11/01/2016
Combination of an Integrin-Targeting NIR Tracer and an Ultrasensitive Spectroscopic Device for Intraoperative Detection of Head and Neck Tumor Margins and Metastatic Lymph Nodes. Tomography (Ann Arbor, Mich.)	Y Yoon, AM Mohs, MC Mancini, S Nie, H Shim	09/01/2016
Downregulation of microRNA-206 promotes invasion and angiogenesis of triple negative breast cancer. Biochemical and biophysical research communications	Z Liang, X Bian, H Shim	08/26/2016
Symmetrical bis-tertiary amines as novel CXCR4 inhibitors. European journal of medicinal chemistry	R Bai, Z Liang, Y Yoon, S Liu, T Gaines, Y Oum, Q Shi, SR Mooring, H Shim	08/08/2016
Whole-brain spectroscopic MRI biomarkers identify infiltrating margins in glioblastoma patients. Neuro-oncology	JS Cordova, HK Shu, Z Liang, SS Gurbani, LA Cooper, CA Holder, JJ Olson, B Kairdolf, E Schreibmann, SG Neill, CG Hadjipanayis, H Shim	08/01/2016
Semi-Automated Volumetric and Morphological Assessment of Glioblastoma Resection with Fluorescence-Guided Surgery. Molecular imaging and biology	JS Cordova, SS Gurbani, CA Holder, JJ Olson, E Schreibmann, R Shi, Y Guo, HK Shu, H Shim, CG Hadjipanayis	06/01/2016
A systematic pipeline for the objective comparison of whole-brain spectroscopic MRI with histology in biopsy specimens from grade III glioma. Tomography (Ann Arbor, Mich.)	JS Cordova, SS Gurbani, JJ Olson, Z Liang, LA Cooper, HG Shu, E Schreibmann, SG Neill, CG Hadjipanayis, CA Holder, H Shim	06/01/2016
Deletion of Na+/H+ exchanger regulatory factor 2 represses colon cancer progress by suppression of Stat3 and CD24. American journal of physiology. Gastrointestinal and liver physiology	M Yoshida, L Zhao, G Grigoryan, H Shim, P He, CC Yun	04/15/2016
Eliminating the heart from the curcumin molecule: monocarbonyl curcumin mimics (MACs). Molecules (Basel, Switzerland)	D Shetty, YJ Kim, H Shim, JP Snyder	12/24/2014
Use of high-resolution volumetric MR spectroscopic imaging in assessing treatment response of glioblastoma to an HDAC inhibitor. AJR. American journal of roentgenology	H Shim, L Wei, CA Holder, Y Guo, XP Hu, AH Miller, JJ Olson	08/01/2014
Inhibition of breast cancer metastasis with microRNA-302a by downregulation of CXCR4 expression. Breast cancer research and treatment	Z Liang, X Bian, H Shim	08/01/2014
Letter to cancer center directors: Progress in quantitative imaging as a means to predict and/or measure tumor response in cancer therapy trials. Journal of clinical oncology : official journal of the American Society of Clinical Oncology	JM Mountz, TE Yankeelov, DL Rubin, JM Buatti, BJ Erikson, FM Fennessy, RJ Gillies, W Huang, MA Jacobs, PE Kinahan, CM Laymon, HM Linden, DA Mankoff, LH Schwartz, H Shim, RL Wahl	07/01/2014
Synthesis of pyridine derivatives as potential antagonists of chemokine receptor type 4. Heterocyclic communications	SR Mooring, T Gaines, Z Liang, H Shim	05/01/2014
Current approaches to the treatment of metastatic brain tumours. Nature reviews. Clinical oncology	TK Owonikoko, J Arbiser, A Zelnak, HK Shu, H Shim, AM Robin, SN Kalkanis, TG Whitsett, B Salhia, NL Tran, T Ryken, MK Moore, KM Egan, JJ Olson	04/01/2014
Al18F-NODA-butyric acid: biological evaluation of a new PET renal radiotracer. Nuclear medicine and biology	M Lipowska, J Klenc, D Shetty, JA Nye, H Shim, AT Taylor	03/01/2014
Quantitative tumor segmentation for evaluation of extent of glioblastoma resection to facilitate multisite clinical trials. Translational oncology	JS Cordova, E Schreibmann, CG Hadjipanayis, Y Guo, HK Shu, H Shim, CA Holder	02/01/2014
Magnetic resonance spectroscopic imaging in the era of pseudoprogression and pseudoresponse in glioblastoma patient management. CNS oncology	H Shim, CA Holder, JJ Olson	09/01/2013
Regulation of hypoxia-inducible factor 1α (HIF-1α) by lysophosphatidic acid is dependent on interplay between p53 and Krüppel-like factor 5. The Journal of biological chemistry	SJ Lee, YR No, DT Dang, LH Dang, VW Yang, H Shim, CC Yun	08/30/2013
Monocarbonyl curcumin analogues: heterocyclic pleiotropic kinase inhibitors that mediate anticancer properties. Journal of medicinal chemistry	A Brown, Q Shi, TW Moore, Y Yoon, A Prussia, C Maddox, DC Liotta, H Shim, JP Snyder	05/09/2013
Benzenesulfonamides: a unique class of chemokine receptor type 4 inhibitors. ChemMedChem	SR Mooring, J Liu, Z Liang, J Ahn, S Hong, Y Yoon, JP Snyder, H Shim	04/01/2013
MicroRNA-302 replacement therapy sensitizes breast cancer cells to ionizing radiation. Pharmaceutical research	Z Liang, J Ahn, D Guo, JR Votaw, H Shim	04/01/2013
Inhibition of the CXCL12/CXCR4-axis as preventive therapy for radiation-induced pulmonary fibrosis. PloS one	HK Shu, Y Yoon, S Hong, K Xu, H Gao, C Hao, E Torres-Gonzalez, C Nayra, M Rojas, H Shim	01/01/2013
Early prediction of response to Vorinostat in an orthotopic rat glioma model. NMR in biomedicine	L Wei, S Hong, Y Yoon, SN Hwang, JC Park, Z Zhang, JJ Olson, XP Hu, H Shim	09/01/2012
Application of metabolic PET imaging in radiation oncology. Radiation research	A Zhu, DM Marcus, HK Shu, H Shim	04/01/2012
Inhibition of the NF-κB signaling pathway by the curcumin analog, 3,5-Bis(2-pyridinylmethylidene)-4-piperidone (EF31): anti-inflammatory and anti-cancer properties. International immunopharmacology	A Olivera, TW Moore, F Hu, AP Brown, A Sun, DC Liotta, JP Snyder, Y Yoon, H Shim, AI Marcus, AH Miller, TW Pace	02/01/2012
Stroma targeting nuclear imaging and radiopharmaceuticals. International journal of molecular imaging	D Shetty, JM Jeong, H Shim	01/01/2012
Development of a unique small molecule modulator of CXCR4. PloS one	Z Liang, W Zhan, A Zhu, Y Yoon, S Lin, M Sasaki, JM Klapproth, H Yang, HE Grossniklaus, J Xu, M Rojas, RJ Voll, MM Goodman, RF Arrendale, J Liu, CC Yun, JP Snyder, DC Liotta, H Shim	01/01/2012
Regulation of miR-19 to breast cancer chemoresistance through targeting PTEN. Pharmaceutical research	Z Liang, Y Li, K Huang, N Wagar, H Shim	12/01/2011
Potential Biomarker of L-type Amino Acid Transporter 1 in Breast Cancer Progression. Nuclear medicine and molecular imaging	Z Liang, HT Cho, L Williams, A Zhu, K Liang, K Huang, H Wu, C Jiang, S Hong, R Crowe, MM Goodman, H Shim	06/01/2011
MAGI-3 competes with NHERF-2 to negatively regulate LPA2 receptor signaling in colon cancer cells. Gastroenterology	SJ Lee, SL Ritter, H Zhang, H Shim, RA Hall, CC Yun	03/01/2011
Current molecular imaging positron emitting radiotracers in oncology. Nuclear medicine and molecular imaging	A Zhu, H Shim	03/01/2011
Introduction: molecular imaging in oncology. Seminars in oncology	H Shim, CC Meltzer	02/01/2011
Metabolic positron emission tomography imaging in cancer detection and therapy response. Seminars in oncology	A Zhu, D Lee, H Shim	02/01/2011
Dipyrimidine amines: a novel class of chemokine receptor type 4 antagonists with high specificity. Journal of medicinal chemistry	A Zhu, W Zhan, Z Liang, Y Yoon, H Yang, HE Grossniklaus, J Xu, M Rojas, M Lockwood, JP Snyder, DC Liotta, H Shim	12/23/2010
The absence of LPA receptor 2 reduces the tumorigenesis by ApcMin mutation in the intestine. American journal of physiology. Gastrointestinal and liver physiology	S Lin, SJ Lee, H Shim, J Chun, CC Yun	11/01/2010
Involvement of miR-326 in chemotherapy resistance of breast cancer through modulating expression of multidrug resistance-associated protein 1. Biochemical pharmacology	Z Liang, H Wu, J Xia, Y Li, Y Zhang, K Huang, N Wagar, Y Yoon, HT Cho, S Scala, H Shim	03/15/2010
The absence of LPA2 attenuates tumor formation in an experimental model of colitis-associated cancer. Gastroenterology	S Lin, D Wang, S Iyer, AM Ghaleb, H Shim, VW Yang, J Chun, CC Yun	05/01/2009
Chemokine receptor CXCR4 as a therapeutic target for neuroectodermal tumors. Seminars in cancer biology	H Shim, S Oishi, N Fujii	04/01/2009
Vasculostatin inhibits intracranial glioma growth and negatively regulates in vivo angiogenesis through a CD36-dependent mechanism. Cancer research	B Kaur, SM Cork, EM Sandberg, NS Devi, Z Zhang, PA Klenotic, M Febbraio, H Shim, H Mao, C Tucker-Burden, RL Silverstein, DJ Brat, JJ Olson, EG Van Meir	02/01/2009
Attenuation of obliterative bronchiolitis by a CXCR4 antagonist in the murine heterotopic tracheal transplant model. The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation	J Xu, E Torres, AL Mora, H Shim, A Ramirez, D Neujahr, KL Brigham, M Rojas	12/01/2008
Targeting tissue factor-expressing tumor angiogenesis and tumors with EF24 conjugated to factor VIIa. Journal of drug targeting	M Shoji, A Sun, W Kisiel, YJ Lu, H Shim, BE McCarey, C Nichols, ET Parker, J Pohl, CA Mosley, AR Alizadeh, DC Liotta, JP Snyder	04/01/2008
Inhibition of breast cancer metastasis by selective synthetic polypeptide against CXCR4. Cancer research	Z Liang, T Wu, H Lou, X Yu, RS Taichman, SK Lau, S Nie, J Umbreit, H Shim	06/15/2004