Hui-Kuo Shu, MD, PhD, FASTRO

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Role

Radiation Oncology
Specialty

Brain and Spine Tumors Ocular Melanoma
Research Program

Discovery and Developmental Therapeutics
Practicing Since

1999

Call 404-778-3473

Background

Board certified in radiation oncology, Hui-Kuo Shu, MD, PhD, FASTRO, specializes in the treatment of brain and spine tumors. Dr. Shu has extensive expertise in the use of advanced radiotherapy techniques including intensity-modulated radiation therapy, stereotactic radiosurgery, fractionated stereotactic radiotherapy, extracranial radiosurgery and image-guided radiation therapy. He treats patients at Winship Cancer Institute and Emory Proton Therapy Center.

Dr. Shu was appointed assistant professor in radiation oncology at the University of Pennsylvania in 1999. He also served as the main radiation oncologist for the treatment of pediatric brain tumors at the Children's Hospital of Philadelphia from 2001 to 2005. He was recruited to Emory University as a physician-scientist and was appointed associate professor in the department of radiation oncology in 2005.

Dr. Shu is a member of the Cancer Cell Biology research program at Winship Cancer Institute. He is a Fellow of the American Society for Radiation Oncology. He is also a member of the American Society for Clinical Oncology, Pediatric Brain Tumor Consortium, American Association for Cancer Research and Society for Neuro-Oncology, among other organizations.

Dr. Shu received his MD and PhD degrees in the NIH-sponsored Medical Scientist Training Program at Case Western Reserve University in Cleveland, Ohio. He completed post-graduate training with a year in internal medicine at University Hospitals of Cleveland, followed by a 5-year radiation oncology residency and fellowship at the University of California in San Francisco (UCSF).

At UCSF, he received grants from the American Society for Therapeutic Radiology and Oncology and the Radiological Society of North America to fund his fellowship research on malignant nervous system tumors. He was honored with awards and appointments during his training including the American Radium Society’s Young Oncologist Essay Award, the RSNA Roentgen Resident/Fellow Research Award at UCSF and chief resident in radiation oncology.

Titles & Roles

Professor, Department of Radiation Oncology

Emory University School of Medicine

Education & Training

Education

Residency, Radiation Oncology, 1999
UCSF Medical Center
Internship, Medicine, 1994
University Hospitals of Cleveland
Medical Education, MD, 1993
Case Western Reserve University

Board Certifications

Radiation Oncology
American Board of Radiology, 1999

Professional Memberships

American Association for Cancer Research
American Society for Clinical Oncology
Pediatric Brain Tumor Consortium
Society for Neuro-Oncology

Research

Publications

Title/Journal	Authors	Publication Date
Risk of late radiation necrosis more than 5 years after stereotactic radiosurgery. Journal of neurosurgery	NS McCall, A Lu, BD Hopkins, D Qian, KB Hoang, JJ Olson, J Zhong, BR Eaton, HG Shu	04/01/2025
T1-contrast enhanced MRI generation from multi-parametric MRI for glioma patients with latent tumor conditioning. Medical physics	Z Eidex, M Safari, RLJ Qiu, DS Yu, HK Shu, H Mao, X Yang	04/01/2025
Incidental High-Grade Sellar Solitary Fibrous Tumor Mimicking Non-Functioning Pituitary Adenoma: A Case Report and Literature Review. The American journal of case reports	M Persico, BD Weinberg, SG Neill, HK Shu, J Zhong	03/15/2025
Impact of Systemic and Radiation Therapy on Survival of Primary Central Nervous System Lymphoma. Cancers	JR Janopaul-Naylor, JS Patel, M Rupji, KB Hoang, NS McCall, DC Qian, ML Shoaf, S Kothari, JJ Olson, HG Shu, A Voloschin, J Zhong, SG Neill, B Eaton	02/12/2025
Deep learning based apparent diffusion coefficient map generation from multi-parametric MR images for patients with diffuse gliomas. Medical physics	Z Eidex, M Safari, J Wynne, RLJ Qiu, T Wang, D Viar-Hernandez, HK Shu, H Mao, X Yang	02/01/2025
Conference Report: Review of Clinical Implementation of Advanced Quantitative Imaging Techniques for Personalized Radiotherapy. Tomography (Ann Arbor, Mich.)	Y Vinogradskiy, H Bahig, NW Bucknell, J Buchsbaum, HG Shu	11/14/2024
Prediction of early recurrence of adult-type diffuse gliomas following radiotherapy using multi-modal magnetic resonance images. Medical physics	E Salari, X Chen, JF Wynne, RLJ Qiu, J Roper, HK Shu, X Yang	11/01/2024
The Impact of Social Determinants on Receipt of Adjuvant Radiation Nationally Following Atypical Meningioma Surgery. World neurosurgery	Z Chisango, O Ugochukwu, XJ Zhi, J Zhong, B Eaton, HK Shu, A Jahangiri, D Bray, K Hoang	10/01/2024
Radiomic Analysis of Treatment Effect for Patients with Radiation Necrosis Treated with Pentoxifylline and Vitamin E. Tomography (Ann Arbor, Mich.)	JS Patel, E Salari, X Chen, J Switchenko, BR Eaton, J Zhong, X Yang, HG Shu, LJ Sudmeier	09/09/2024
Patterns of Treatment Failure in Primary Central Nervous System Lymphoma. American journal of clinical oncology	JR Janopaul-Naylor, JS Patel, M Rupji, DC Qian, KB Hoang, NS McCall, AJ Schlafstein, ML Shoaf, S Kothari, JJ Olson, HK Shu, J Zhong, SG Neill, B Eaton	07/01/2024
High-resolution 3T to 7T ADC map synthesis with a hybrid CNN-transformer model. Medical physics	Z Eidex, J Wang, M Safari, E Elder, J Wynne, T Wang, HK Shu, H Mao, X Yang	06/01/2024
The Utility of Spectroscopic MRI in Stereotactic Biopsy and Radiotherapy Guidance in Newly Diagnosed Glioblastoma. Tomography (Ann Arbor, Mich.)	AC Rejimon, KK Ramesh, AG Trivedi, V Huang, E Schreibmann, BD Weinberg, LR Kleinberg, HG Shu, H Shim, JJ Olson	03/20/2024
High-resolution MRI synthesis using a data-driven framework with denoising diffusion probabilistic modeling. Physics in medicine and biology	CW Chang, J Peng, M Safari, E Salari, S Pan, J Roper, RLJ Qiu, Y Gao, HK Shu, H Mao, X Yang	02/05/2024
SPECTRO GLIO trial aftermath: Where do we go from here? Neuro-oncology	HG Shu, H Shim	01/05/2024
MGMT promoter methylation prediction based on multiparametric MRI via vision graph neural network. Journal of medical imaging (Bellingham, Wash.)	M Hu, K Yang, J Wang, RLJ Qiu, J Roper, S Kahn, HK Shu, X Yang	01/01/2024
Hippocampus substructure segmentation using morphological vision transformer learning. Physics in medicine and biology	Y Lei, Y Ding, RLJ Qiu, T Wang, J Roper, Y Fu, HK Shu, H Mao, X Yang	12/01/2023
Examining the Effect of ALK and EGFR Mutations on Survival Outcomes in Surgical Lung Brain Metastasis Patients. Cancers	SS Mannam, DP Bray, CD Nwagwu, J Zhong, HK Shu, B Eaton, L Sudmeier, S Goyal, C Deibert, EK Nduom, J Olson, KB Hoang	09/28/2023
A Fully Automated Post-Surgical Brain Tumor Segmentation Model for Radiation Treatment Planning and Longitudinal Tracking. Cancers	KK Ramesh, KM Xu, AG Trivedi, V Huang, VK Sharghi, LR Kleinberg, EA Mellon, HG Shu, H Shim, BD Weinberg	08/03/2023
Spectroscopic MRI-Based Biomarkers Predict Survival for Newly Diagnosed Glioblastoma in a Clinical Trial. Cancers	AG Trivedi, KK Ramesh, V Huang, EA Mellon, PB Barker, LR Kleinberg, BD Weinberg, HG Shu, H Shim	07/07/2023
Hippocampus Substructure Segmentation Using Morphological Vision Transformer Learning. ArXiv	Y Lei, Y Ding, RLJ Qiu, T Wang, J Roper, Y Fu, HK Shu, H Mao, X Yang	06/14/2023
Applying a Radiation Therapy Volume Analysis Pipeline to Determine the Utility of Spectroscopic MRI-Guided Adaptive Radiation Therapy for Glioblastoma. Tomography (Ann Arbor, Mich.)	AG Trivedi, SH Kim, KK Ramesh, AS Giuffrida, BD Weinberg, EA Mellon, LR Kleinberg, PB Barker, H Han, HG Shu, H Shim, E Schreibmann	05/21/2023
Mutant Isocitrate Dehydrogenase 1 Expression Enhances Response of Gliomas to the Histone Deacetylase Inhibitor Belinostat. Tomography (Ann Arbor, Mich.)	CM Chang, KK Ramesh, V Huang, S Gurbani, LR Kleinberg, BD Weinberg, H Shim, HG Shu	05/04/2023
Using Brain Tumor MRI Structured Reporting to Quantify the Impact of Imaging on Brain Tumor Boards. Tomography (Ann Arbor, Mich.)	SA Abidi, MJ Hoch, R Hu, G Sadigh, A Voloschin, JJ Olson, HG Shu, SG Neill, BD Weinberg	04/18/2023
A Novel Approach to Determining Tumor Progression Using a Three-Site Pilot Clinical Trial of Spectroscopic MRI-Guided Radiation Dose Escalation in Glioblastoma. Tomography (Ann Arbor, Mich.)	KK Ramesh, V Huang, J Rosenthal, EA Mellon, M Goryawala, PB Barker, SS Gurbani, AG Trivedi, AS Giuffrida, E Schreibmann, H Han, M de le Fuente, EM Dunbar, M Holdhoff, LR Kleinberg, HG Shu, H Shim, BD Weinberg	02/06/2023
Development and validation of a prognostic gene expression signature for lower-grade glioma following surgery and adjuvant radiotherapy. Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology	DC Qian, JA Marascio, R Tobillo, JW Lorenz, NS McCall, SG Neill, KB Hoang, JJ Olson, BR Eaton, HG Shu, J Zhong	10/01/2022
Automatic inverse treatment planning of Gamma Knife radiosurgery via deep reinforcement learning. Medical physics	Y Liu, C Shen, T Wang, J Zhang, X Yang, T Liu, S Kahn, HK Shu, Z Tian	05/01/2022
Cascaded mutual enhancing networks for brain tumor subregion segmentation in multiparametric MRI. Physics in medicine and biology	S Momin, Y Lei, Z Tian, J Roper, J Lin, S Kahn, HK Shu, J Bradley, T Liu, X Yang	04/11/2022
Modern Linear Accelerator-Based Radiotherapy Is Safe and Effective in the Treatment of Secretory and Nonsecretory Pituitary Adenomas. World neurosurgery	JR Janopaul-Naylor, M Rupji, J Zhong, BR Eaton, N Ali, AG Ioachimescu, NM Oyesiku, HG Shu	04/01/2022
Final Report on Clinical Outcomes and Tumor Recurrence Patterns of a Pilot Study Assessing Efficacy of Belinostat (PXD-101) with Chemoradiation for Newly Diagnosed Glioblastoma. Tomography (Ann Arbor, Mich.)	K Xu, K Ramesh, V Huang, SS Gurbani, JS Cordova, E Schreibmann, BD Weinberg, S Sengupta, AD Voloschin, M Holdhoff, PB Barker, LR Kleinberg, JJ Olson, HG Shu, H Shim	03/03/2022
Race, Ethnicity, and Sex Among Senior Faculty in Radiation Oncology From 2000 to 2019. JAMA network open	JR Janopaul-Naylor, SE Roberts, HK Shu, AH Kesarwala, JY Lin, JM Switchenko, MA Torres	01/04/2022
A multi-institutional pilot clinical trial of spectroscopic MRI-guided radiation dose escalation for newly diagnosed glioblastoma. Neuro-oncology advances	K Ramesh, EA Mellon, SS Gurbani, BD Weinberg, E Schreibmann, SA Sheriff, M Goryawala, M de le Fuente, BR Eaton, J Zhong, AD Voloschin, S Sengupta, EM Dunbar, M Holdhoff, PB Barker, AA Maudsley, LR Kleinberg, H Shim, HG Shu	01/01/2022
MRI classification using semantic random forest with auto-context model. Quantitative imaging in medicine and surgery	Y Lei, T Wang, X Dong, S Tian, Y Liu, H Mao, WJ Curran, HK Shu, T Liu, X Yang	12/01/2021
Surgical Outcomes of Novel Collagen Tile Cesium Brachytherapy for Recurrent Intracranial Tumors at a Tertiary Referral Center. Cureus	KT Warren, A Boucher, DP Bray, S Dresser, J Zhong, HK Shu, J Olson, K Hoang	11/01/2021
3D whole-brain metabolite imaging to improve characterization of low-to-intermediate grade gliomas. Journal of neuro-oncology	J Zhong, V Huang, SS Gurbani, K Ramesh, J Scott Cordova, E Schreibmann, HG Shu, J Olson, H Han, A Giuffrida, H Shim, BD Weinberg	06/01/2021
Quantitation of cancer treatment response by 2-[¹⁸F]FDG PET/CT: multi-center assessment of measurement variability using AUTO-PERCIST™. EJNMMI research	JH O, SJ Lim, H Wang, JP Leal, HG Shu, RL Wahl	02/12/2021
Co-Occurrence Conundrum: Brain Metastases from Lung Adenocarcinoma, Radiation Necrosis, and Gliosarcoma. Case reports in oncology	DC Qian, BD Weinberg, SG Neill, AL Goodman, JJ Olson, AD Voloschin, SS Ramalingam, HG Shu	01/01/2021
Characterization of dysregulated glutamine metabolism in human glioma tissue with ¹H NMR. Scientific reports	S Ekici, BB Risk, SG Neill, HK Shu, CC Fleischer	11/24/2020
Brain tumor segmentation using 3D Mask R-CNN for dynamic susceptibility contrast enhanced perfusion imaging. Physics in medicine and biology	J Jeong, Y Lei, S Kahn, T Liu, WJ Curran, HK Shu, H Mao, X Yang	09/18/2020
Optimal timing of chemoradiotherapy after surgical resection of glioblastoma: Stratification by validated prognostic classification. Cancer	RH Press, SL Shafer, R Jiang, ZS Buchwald, M Abugideiri, S Tian, TM Morgan, M Behera, S Sengupta, AD Voloschin, JJ Olson, S Hasan, DT Blumenthal, WJ Curran, BR Eaton, HG Shu, J Zhong	07/15/2020
Clinical Trial Design and Development Work Group Within the Quantitative Imaging Network. Tomography (Ann Arbor, Mich.)	EF Jones, JM Buatti, HK Shu, RL Wahl, BF Kurland, HM Linden, DA Mankoff, DL Rubin, D Tata, RJ Nordstrom, L Hadjiyski, M Holdhoff, LH Schwartz	06/01/2020
The Longitudinal Imaging Tracker (BrICS-LIT):A Cloud Platform for Monitoring Treatment Response in Glioblastoma Patients. Tomography (Ann Arbor, Mich.)	K Ramesh, SS Gurbani, EA Mellon, V Huang, M Goryawala, PB Barker, L Kleinberg, HG Shu, H Shim, BD Weinberg	06/01/2020
Genomic copy number variation correlates with survival outcomes in WHO grade IV glioma. Scientific reports	ZS Buchwald, S Tian, M Rossi, GH Smith, J Switchenko, JE Hauenstein, CS Moreno, RH Press, RS Prabhu, J Zhong, DF Saxe, SG Neill, JJ Olson, IR Crocker, WJ Curran, HG Shu	04/30/2020
High-risk Meningioma: Initial Outcomes From NRG Oncology/RTOG 0539. International journal of radiation oncology, biology, physics	CL Rogers, M Won, MA Vogelbaum, A Perry, LS Ashby, JM Modi, AM Alleman, J Galvin, SE Fogh, E Youssef, N Deb, Y Kwok, CG Robinson, HK Shu, BJ Fisher, V Panet-Raymond, WG McMillan, JF de Groot, P Zhang, MP Mehta	03/15/2020
Outcomes of whole-brain radiation with simultaneous in-field boost (SIB) for the treatment of brain metastases. Journal of neuro-oncology	J Zhong, AD Waldman, S Kandula, BR Eaton, RS Prabhu, SB Huff, HG Shu	03/01/2020
Third Nerve Palsy Due to a Malignant Oculomotor Nerve Sheath Tumor. Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society	JA Micieli, HG Shu, NJ Newman	03/01/2020
Remarkable response of a patient with secondary glioblastoma to a histone deacetylase inhibitor. Oxford medical case reports	SS Gurbani, BD Weinberg, E Salgado, A Voloschin, JE Velazquez Vega, JJ Olson, HG Shu, H Shim	03/01/2020
Moderately Hypofractionated Radiation for Benign Meningiomas and Schwannomas: A Report of 70 Patients Treated Between 2008 and 2018. Advances in radiation oncology	VR Dhere, S Tian, Z Buchwald, X Jiang, C Zhang, Z Chen, BR Eaton, HG Shu, WJ Curran, J Zhong	01/01/2020
Reduced-volume tumor-bed boost is not associated with inferior local control and survival outcomes in high-risk medulloblastoma. Pediatric blood & cancer	S Tian, LJ Sudmeier, C Zhang, NA Madden, ZS Buchwald, HG Shu, WJ Curran, BR Eaton, N Esiashvili	01/01/2020
Dosimetric Factors Related to Radiation Necrosis After 5-Fraction Radiosurgery for Patients With Resected Brain Metastases. Practical radiation oncology	DG Tanenbaum, ZS Buchwald, J Jhaveri, E Schreibmann, JM Switchenko, RS Prabhu, M Chowdhary, M Abugideiri, NT Pfister, B Eaton, SE Kahn, JJ Olson, HG Shu, IR Crocker, WJ Curran, KR Patel	01/01/2020
Dosimetric study on learning-based cone-beam CT correction in adaptive radiation therapy. Medical dosimetry : official journal of the American Association of Medical Dosimetrists	T Wang, Y Lei, N Manohar, S Tian, AB Jani, HK Shu, K Higgins, A Dhabaan, P Patel, X Tang, T Liu, WJ Curran, X Yang	12/01/2019
Hemorrhagic and Cystic Brain Metastases Are Associated With an Increased Risk of Leptomeningeal Dissemination After Surgical Resection and Adjuvant Stereotactic Radiosurgery. Neurosurgery	RH Press, C Zhang, M Chowdhary, RS Prabhu, MJ Ferris, KM Xu, JJ Olson, BR Eaton, HG Shu, WJ Curran, IR Crocker, KR Patel	11/01/2019
Deep learning-based image quality improvement for low-dose computed tomography simulation in radiation therapy. Journal of medical imaging (Bellingham, Wash.)	T Wang, Y Lei, Z Tian, X Dong, Y Liu, X Jiang, WJ Curran, T Liu, HK Shu, X Yang	10/01/2019
MRI-based treatment planning for brain stereotactic radiosurgery: Dosimetric validation of a learning-based pseudo-CT generation method. Medical dosimetry : official journal of the American Association of Medical Dosimetrists	T Wang, N Manohar, Y Lei, A Dhabaan, HK Shu, T Liu, WJ Curran, X Yang	09/01/2019
MRI-only based synthetic CT generation using dense cycle consistent generative adversarial networks. Medical physics	Y Lei, J Harms, T Wang, Y Liu, HK Shu, AB Jani, WJ Curran, H Mao, T Liu, X Yang	08/01/2019
The Role of Standard and Advanced Imaging for the Management of Brain Malignancies From a Radiation Oncology Standpoint. Neurosurgery	RH Press, J Zhong, SS Gurbani, BD Weinberg, BR Eaton, H Shim, HG Shu	08/01/2019
Institutional Implementation of a Structured Reporting System: Our Experience with the Brain Tumor Reporting and Data System. Academic radiology	A Gore, MJ Hoch, HG Shu, JJ Olson, AD Voloschin, BD Weinberg	07/01/2019
Learning-based automatic segmentation of arteriovenous malformations on contrast CT images in brain stereotactic radiosurgery. Medical physics	T Wang, Y Lei, S Tian, X Jiang, J Zhou, T Liu, S Dresser, WJ Curran, HK Shu, X Yang	07/01/2019
Glioblastoma with brainstem leptomeningeal pseudoprogression following radiation therapy. Radiology case reports	N Kinger, MJ Hoch, HG Shu, BD Weinberg	05/01/2019
MRI-based synthetic CT generation using semantic random forest with iterative refinement. Physics in medicine and biology	Y Lei, J Harms, T Wang, S Tian, J Zhou, HK Shu, J Zhong, H Mao, WJ Curran, T Liu, X Yang	04/05/2019
Does size matter? Investigating the optimal planning target volume margin for postoperative stereotactic radiosurgery to resected brain metastases. Journal of neurosurgery	J Jhaveri, M Chowdhary, X Zhang, RH Press, JM Switchenko, MJ Ferris, TM Morgan, J Roper, A Dhabaan, E Elder, BR Eaton, JJ Olson, WJ Curran, HG Shu, IR Crocker, KR Patel	03/01/2019
Assessing Treatment Response of Glioblastoma to an HDAC Inhibitor Using Whole-Brain Spectroscopic MRI. Tomography (Ann Arbor, Mich.)	SS Gurbani, Y Yoon, BD Weinberg, E Salgado, RH Press, JS Cordova, KK Ramesh, Z Liang, J Velazquez Vega, A Voloschin, JJ Olson, E Schreibmann, H Shim, HG Shu	03/01/2019
The Brain Imaging Collaboration Suite (BrICS): A Cloud Platform for Integrating Whole-Brain Spectroscopic MRI into the Radiation Therapy Planning Workflow. Tomography (Ann Arbor, Mich.)	S Gurbani, B Weinberg, L Cooper, E Mellon, E Schreibmann, S Sheriff, A Maudsley, M Goryawala, HK Shu, H Shim	03/01/2019
MRI-Based Proton Treatment Planning for Base of Skull Tumors. International journal of particle therapy	G Shafai-Erfani, Y Lei, Y Liu, Y Wang, T Wang, J Zhong, T Liu, M McDonald, WJ Curran, J Zhou, HK Shu, X Yang	01/01/2019
Fractionated Radiotherapy Is Associated with Lower Rates of Treatment-Related Edema than Stereotactic Radiosurgery in Magnetic Resonance Imaging-Defined Meningiomas. World neurosurgery	TM Morgan, D Zaenger, JM Switchenko, BR Eaton, IR Crocker, AN Ali, HG Shu	01/01/2019
The role of erlotinib and the Optune device in a patient with an epidermal growth factor receptor viii amplified glioblastoma. Oxford medical case reports	SP Doyle, SS Gurbani, AS Ross, H Rosen, CD Barrett, JJ Olson, H Shim, HK Shu, S Sengupta	12/01/2018
The Use of Quantitative Imaging in Radiation Oncology: A Quantitative Imaging Network (QIN) Perspective. International journal of radiation oncology, biology, physics	RH Press, HG Shu, H Shim, JM Mountz, BF Kurland, RL Wahl, EF Jones, NM Hylton, ER Gerstner, RJ Nordstrom, L Henderson, KA Kurdziel, B Vikram, MA Jacobs, M Holdhoff, E Taylor, DA Jaffray, LH Schwartz, DA Mankoff, PE Kinahan, HM Linden, P Lambin, TJ Dilling, DL Rubin, L Hadjiiski, JM Buatti	11/15/2018
The use of Hypofractionated Radiosurgery for the Treatment of Intracranial Lesions Unsuitable for Single-Fraction Radiosurgery. Neurosurgery	J Zhong, RH Press, JJ Olson, NM Oyesiku, HG Shu, BR Eaton	11/01/2018
MRI-based pseudo CT synthesis using anatomical signature and alternating random forest with iterative refinement model. Journal of medical imaging (Bellingham, Wash.)	Y Lei, JJ Jeong, T Wang, HK Shu, P Patel, S Tian, T Liu, H Shim, H Mao, AB Jani, WJ Curran, X Yang	10/01/2018
Targeted sequencing and intracranial outcomes of patients with lung adenocarcinoma brain metastases treated with radiotherapy. Cancer	RH Press, C Zhang, RJ Cassidy, MJ Ferris, J Zhong, CE Steuer, RN Pillai, TK Owonikoko, S Kahn, SS Ramalingam, PR Patel, WJ Curran, HG Shu, GL Sica, KA Higgins	09/01/2018
Post-treatment neutrophil-to-lymphocyte ratio predicts for overall survival in brain metastases treated with stereotactic radiosurgery. Journal of neuro-oncology	M Chowdhary, JM Switchenko, RH Press, J Jhaveri, ZS Buchwald, PA Blumenfeld, G Marwaha, A Diaz, D Wang, RA Abrams, JJ Olson, HG Shu, WJ Curran, KR Patel	09/01/2018
Magnetic resonance imaging-based pseudo computed tomography using anatomic signature and joint dictionary learning. Journal of medical imaging (Bellingham, Wash.)	Y Lei, HK Shu, S Tian, JJ Jeong, T Liu, H Shim, H Mao, T Wang, AB Jani, WJ Curran, X Yang	07/01/2018
Management-Based Structured Reporting of Posttreatment Glioma Response With the Brain Tumor Reporting and Data System. Journal of the American College of Radiology : JACR	BD Weinberg, A Gore, HG Shu, JJ Olson, R Duszak, AD Voloschin, MJ Hoch	05/01/2018
Radiation Oncology Review Series. Neurosurgery	HG Shu	05/01/2018
Is less more? Comparing chemotherapy alone with chemotherapy and radiation for high-risk grade 2 glioma: An analysis of the National Cancer Data Base. Cancer	J Jhaveri, Y Liu, M Chowdhary, ZS Buchwald, TW Gillespie, JJ Olson, AD Voloschin, BR Eaton, HG Shu, IR Crocker, WJ Curran, KR Patel	03/15/2018
External validity of two nomograms for predicting distant brain failure after radiosurgery for brain metastases in a bi-institutional independent patient cohort. Journal of neuro-oncology	RS Prabhu, RH Press, DM Boselli, KR Miller, SP Lankford, RJ McCammon, BJ Moeller, JH Heinzerling, CE Fasola, KR Patel, AL Asher, AL Sumrall, WJ Curran, HG Shu, SH Burri	03/01/2018
Angiotensin receptor blockade: a novel approach for symptomatic radiation necrosis after stereotactic radiosurgery. Journal of neuro-oncology	M Chowdhary, D Okwan-Duodu, JM Switchenko, RH Press, J Jhaveri, ZS Buchwald, J Zhong, BV Chapman, RS Bindra, JN Contessa, HS Park, JB Yu, RH Decker, JJ Olson, NM Oyesiku, RA Abrams, HG Shu, WJ Curran, IR Crocker, KR Patel	01/01/2018
Progesterone improves neurocognitive outcomes following therapeutic cranial irradiation in mice. Hormones and behavior	S Yousuf, DJ Brat, HK Shu, Y Wang, DG Stein, F Atif	11/01/2017
Single-Fraction Stereotactic Radiosurgery (SRS) Alone Versus Surgical Resection and SRS for Large Brain Metastases: A Multi-institutional Analysis. International journal of radiation oncology, biology, physics	RS Prabhu, RH Press, KR Patel, DM Boselli, JT Symanowski, SP Lankford, RJ McCammon, BJ Moeller, JH Heinzerling, CE Fasola, AL Asher, AL Sumrall, ZS Buchwald, WJ Curran, HG Shu, I Crocker, SH Burri	10/01/2017
External Validity of a Risk Stratification Score Predicting Early Distant Brain Failure and Salvage Whole Brain Radiation Therapy After Stereotactic Radiosurgery for Brain Metastases. International journal of radiation oncology, biology, physics	RH Press, DM Boselli, JT Symanowski, SP Lankford, RJ McCammon, BJ Moeller, JH Heinzerling, CE Fasola, SH Burri, KR Patel, AL Asher, AL Sumrall, WJ Curran, HG Shu, IR Crocker, RS Prabhu	07/01/2017
Cyclooxygenase-2 Induction by Amino Acid Deprivation Requires p38 Mitogen-Activated Protein Kinase in Human Glioma Cells. Cancer investigation	Z Li, CM Chang, L Wang, P Zhang, HG Shu	04/21/2017
Comparing pre-operative stereotactic radiosurgery (SRS) to post-operative whole brain radiation therapy (WBRT) for resectable brain metastases: a multi-institutional analysis. Journal of neuro-oncology	KR Patel, SH Burri, D Boselli, JT Symanowski, AL Asher, A Sumrall, RW Fraser, RH Press, J Zhong, RJ Cassidy, JJ Olson, WJ Curran, HG Shu, IR Crocker, RS Prabhu	02/01/2017
Pseudo CT Estimation from MRI Using Patch-based Random Forest. Proceedings of SPIE--the International Society for Optical Engineering	X Yang, Y Lei, HK Shu, P Rossi, H Mao, H Shim, WJ Curran, T Liu	02/01/2017
Attitudes of radiation oncologists toward palliative and supportive care in the United States: Report on national membership survey by the American Society for Radiation Oncology (ASTRO). Practical radiation oncology	RL Wei, MD Mattes, J Yu, A Thrasher, HK Shu, H Paganetti, J De Los Santos, B Koontz, C Abraham, T Balboni	01/01/2017
Postoperative stereotactic radiosurgery for resected brain metastases: A comparison of outcomes for large resection cavities. Practical radiation oncology	J Zhong, MJ Ferris, J Switchenko, RH Press, Z Buchwald, JJ Olson, BR Eaton, WJ Curran, HG Shu, IR Crocker, KR Patel	01/01/2017
Simulating the Effect of Spectroscopic MRI as a Metric for Radiation Therapy Planning in Patients with Glioblastoma. Tomography (Ann Arbor, Mich.)	JS Cordova, S Kandula, S Gurbani, J Zhong, M Tejani, O Kayode, K Patel, R Prabhu, E Schreibmann, I Crocker, CA Holder, H Shim, HK Shu	12/01/2016
Phosphatidylinositol-3 kinase-dependent translational regulation of Id1 involves the PPM1G phosphatase. Oncogene	K Xu, L Wang, W Feng, Y Feng, HK Shu	11/03/2016
Whole-brain spectroscopic MRI biomarkers identify infiltrating margins in glioblastoma patients. Neuro-oncology	JS Cordova, HK Shu, Z Liang, SS Gurbani, LA Cooper, CA Holder, JJ Olson, B Kairdolf, E Schreibmann, SG Neill, CG Hadjipanayis, H Shim	08/01/2016
Comparing Preoperative With Postoperative Stereotactic Radiosurgery for Resectable Brain Metastases: A Multi-institutional Analysis. Neurosurgery	KR Patel, SH Burri, AL Asher, IR Crocker, RW Fraser, C Zhang, Z Chen, S Kandula, J Zhong, RH Press, JJ Olson, NM Oyesiku, SD Wait, WJ Curran, HK Shu, RS Prabhu	08/01/2016
GPRC5A suppresses protein synthesis at the endoplasmic reticulum to prevent radiation-induced lung tumorigenesis. Nature communications	J Wang, AB Farris, K Xu, P Wang, X Zhang, DM Duong, H Yi, HK Shu, SY Sun, Y Wang	06/08/2016
Semi-Automated Volumetric and Morphological Assessment of Glioblastoma Resection with Fluorescence-Guided Surgery. Molecular imaging and biology	JS Cordova, SS Gurbani, CA Holder, JJ Olson, E Schreibmann, R Shi, Y Guo, HK Shu, H Shim, CG Hadjipanayis	06/01/2016
A systematic pipeline for the objective comparison of whole-brain spectroscopic MRI with histology in biopsy specimens from grade III glioma. Tomography (Ann Arbor, Mich.)	JS Cordova, SS Gurbani, JJ Olson, Z Liang, LA Cooper, HG Shu, E Schreibmann, SG Neill, CG Hadjipanayis, CA Holder, H Shim	06/01/2016
Novel risk stratification score for predicting early distant brain failure and salvage whole-brain radiotherapy after stereotactic radiosurgery for brain metastases. Cancer	RH Press, RS Prabhu, DC Nickleach, Y Liu, HK Shu, S Kandula, KR Patel, WJ Curran, I Crocker	11/01/2015
Automated population-based planning for whole brain radiation therapy. Journal of applied clinical medical physics	E Schreibmann, T Fox, W Curran, HK Shu, I Crocker	09/08/2015
Bevacizumab-induced hypertension is a predictive marker for improved outcomes in patients with recurrent glioblastoma treated with bevacizumab. Cancer	J Zhong, AN Ali, AD Voloschin, Y Liu, WJ Curran, IR Crocker, HK Shu	05/01/2015
Erratum to: Hypofractionated radiosurgery has a better safety profile than single fraction radiosurgery for large resected brain metastases. Journal of neuro-oncology	BR Eaton, MJ LaRiviere, S Kim, RS Prabhu, K Patel, S Kandula, N Oyesiku, J Olson, W Curran, HK Shu, I Crocker	05/01/2015
Hypofractionated radiosurgery has a better safety profile than single fraction radiosurgery for large resected brain metastases. Journal of neuro-oncology	BR Eaton, MJ LaRiviere, S Kim, RS Prabhu, K Patel, S Kandula, N Oyesiku, J Olson, W Curran, HK Shu, I Crocker	05/01/2015
Intracranial control and radiographic changes with adjuvant radiation therapy for resected brain metastases: whole brain radiotherapy versus stereotactic radiosurgery alone. Journal of neuro-oncology	KR Patel, RS Prabhu, S Kandula, DE Oliver, S Kim, C Hadjipanayis, JJ Olson, N Oyesiku, WJ Curran, MK Khan, HK Shu, I Crocker	12/01/2014
Patterns of presentation and failure in patients with gliomatosis cerebri treated with partial-brain radiation therapy. Cancer	S Kandula, AM Saindane, RS Prabhu, S Hanasoge, KR Patel, HK Shu, WJ Curran, IR Crocker	09/01/2014
Immunohistochemical demonstration of isocitrate dehydrogenase 1 (IDH1) mutation in a small subset of prostatic carcinomas. Applied immunohistochemistry & molecular morphology : AIMM	SH Mauzo, M Lee, J Petros, S Hunter, CM Chang, HK Shu, AC Bellail, C Hao, C Cohen	04/01/2014
Outcomes and patterns of failure for grade 2 meningioma treated with reduced-margin intensity modulated radiation therapy. International journal of radiation oncology, biology, physics	RH Press, RS Prabhu, CL Appin, DJ Brat, HK Shu, C Hadjipanayis, JJ Olson, NM Oyesiku, WJ Curran, I Crocker	04/01/2014
The feasibility of frameless stereotactic radiosurgery in the management of pediatric central nervous system tumors. Journal of neuro-oncology	R Nanda, A Dhabbaan, A Janss, HK Shu, N Esiashvili	04/01/2014
Current approaches to the treatment of metastatic brain tumours. Nature reviews. Clinical oncology	TK Owonikoko, J Arbiser, A Zelnak, HK Shu, H Shim, AM Robin, SN Kalkanis, TG Whitsett, B Salhia, NL Tran, T Ryken, MK Moore, KM Egan, JJ Olson	04/01/2014
COX-2 overexpression increases malignant potential of human glioma cells through Id1. Oncotarget	K Xu, L Wang, HK Shu	03/15/2014
Quantitative tumor segmentation for evaluation of extent of glioblastoma resection to facilitate multisite clinical trials. Translational oncology	JS Cordova, E Schreibmann, CG Hadjipanayis, Y Guo, HK Shu, H Shim, CA Holder	02/01/2014
Improved hippocampal dose with reduced margin radiotherapy for glioblastoma multiforme. Radiation oncology (London, England)	AN Ali, T Ogunleye, CW Hardy, HK Shu, WJ Curran, IR Crocker	01/10/2014
Opposing effect of EGFRWT on EGFRvIII-mediated NF-κB activation with RIP1 as a cell death switch. Cell reports	VT Puliyappadamba, S Chakraborty, SS Chauncey, L Li, KJ Hatanpaa, B Mickey, S Noorani, HK Shu, S Burma, DA Boothman, AA Habib	08/29/2013
Transcription factor interactions mediate EGF-dependent COX-2 expression. Molecular cancer research : MCR	K Xu, HK Shu	08/01/2013
In vitro and in vivo enhancement of chemoradiation using the oral PARP inhibitor ABT-888 in colorectal cancer cells. International journal of radiation oncology, biology, physics	JW Shelton, TV Waxweiler, J Landry, H Gao, Y Xu, L Wang, B El-Rayes, HK Shu	07/01/2013
Hypofractionated radiosurgery for intact or resected brain metastases: defining the optimal dose and fractionation. Radiation oncology (London, England)	BR Eaton, B Gebhardt, R Prabhu, HK Shu, WJ Curran, I Crocker	06/07/2013
Clinical outcomes for a novel 6 degrees of freedom image guided localization method for frameless radiosurgery for intracranial brain metastases. Journal of neuro-oncology	RS Prabhu, A Dhabaan, WA Hall, T Ogunleye, I Crocker, WJ Curran, HK Shu	05/01/2013
Growth factor receptor-Src-mediated suppression of GRK6 dysregulates CXCR4 signaling and promotes medulloblastoma migration. Molecular cancer	L Yuan, H Zhang, J Liu, JB Rubin, YJ Cho, HK Shu, M Schniederjan, TJ MacDonald	03/05/2013
Association of clinical response and long-term outcome among patients with biopsied orbital pseudotumor receiving modern radiation therapy. International journal of radiation oncology, biology, physics	RS Prabhu, S Kandula, L Liebman, TH Wojno, B Hayek, WA Hall, HK Shu, I Crocker	03/01/2013
Inhibition of the CXCL12/CXCR4-axis as preventive therapy for radiation-induced pulmonary fibrosis. PloS one	HK Shu, Y Yoon, S Hong, K Xu, H Gao, C Hao, E Torres-Gonzalez, C Nayra, M Rojas, H Shim	01/01/2013
Six degrees of freedom CBCT-based positioning for intracranial targets treated with frameless stereotactic radiosurgery. Journal of applied clinical medical physics	A Dhabaan, E Schreibmann, A Siddiqi, E Elder, T Fox, T Ogunleye, N Esiashvili, W Curran, I Crocker, HK Shu	11/08/2012
Comparing central nervous system (CNS) and extra-CNS hemangiopericytomas in the Surveillance, Epidemiology, and End Results program: analysis of 655 patients and review of current literature. Cancer	WA Hall, AN Ali, N Gullett, I Crocker, JC Landry, HK Shu, R Prabhu, W Curran	11/01/2012
Transient enlargement of craniopharyngioma after radiation therapy: pattern of magnetic resonance imaging response following radiation. Journal of neuro-oncology	Z Shi, N Esiashvili, AJ Janss, CM Mazewski, TJ MacDonald, DM Wrubel, B Brahma, FP Schwaibold, RB Marcus, IR Crocker, HK Shu	09/01/2012
A Surveillance, Epidemiology and End Results (SEER) program comparison of adult and pediatric Wilms' tumor. Cancer	AN Ali, R Diaz, HK Shu, AC Paulino, N Esiashvili	05/01/2012
Current dosing paradigm for stereotactic radiosurgery alone after surgical resection of brain metastases needs to be optimized for improved local control. International journal of radiation oncology, biology, physics	R Prabhu, HK Shu, C Hadjipanayis, A Dhabaan, W Hall, B Raore, J Olson, W Curran, N Oyesiku, I Crocker	05/01/2012
Application of metabolic PET imaging in radiation oncology. Radiation research	A Zhu, DM Marcus, HK Shu, H Shim	04/01/2012
Metastasis infiltration: an investigation of the postoperative brain-tumor interface. International journal of radiation oncology, biology, physics	B Raore, M Schniederjan, R Prabhu, DJ Brat, HK Shu, JJ Olson	11/15/2011
Pattern of failure after limited margin radiotherapy and temozolomide for glioblastoma. International journal of radiation oncology, biology, physics	MW McDonald, HK Shu, WJ Curran, IR Crocker	01/01/2011
Stereotactic body radiosurgery for spinal metastatic disease: an evidence-based review. International journal of surgical oncology	WA Hall, LJ Stapleford, CG Hadjipanayis, WJ Curran, I Crocker, HK Shu	01/01/2011
Celecoxib can induce vascular endothelial growth factor expression and tumor angiogenesis. Molecular cancer therapeutics	K Xu, H Gao, HK Shu	01/01/2011
Dosimetric performance of the new high-definition multileaf collimator for intracranial stereotactic radiosurgery. Journal of applied clinical medical physics	A Dhabaan, E Elder, E Schreibmann, I Crocker, WJ Curran, NM Oyesiku, HK Shu, T Fox	06/21/2010
Exciting new advances in neuro-oncology: the avenue to a cure for malignant glioma. CA: a cancer journal for clinicians	EG Van Meir, CG Hadjipanayis, AD Norden, HK Shu, PY Wen, JJ Olson	01/01/2010
Epidermal growth factor-dependent cyclooxygenase-2 induction in gliomas requires protein kinase C-delta. Oncogene	K Xu, CM Chang, H Gao, HK Shu	03/19/2009
A vascular targeted pan phosphoinositide 3-kinase inhibitor prodrug, SF1126, with antitumor and antiangiogenic activity. Cancer research	JR Garlich, P De, N Dey, JD Su, X Peng, A Miller, R Murali, Y Lu, GB Mills, V Kundra, HK Shu, Q Peng, DL Durden	01/01/2008

Awards

Dr. Shu has been listed multiple times as one of Atlanta Magazine's "Top Doctors" and appeared on the cover of the special issue in 2017.

Ratings & Reviews

Patients who are treated in outpatient and inpatient environments are eligible to receive a survey related to their individual care. Displayed ratings and reviews are displayed for Providers who have received at least 30 returned surveys over a 12-month period and are related to all Care Provider related survey questions. To help our patients better understand our Transparency program (ratings and review), the motivations behind it, how ratings are calculated, why ratings and reviews are not published for every EHC Provider, and how this information can be helpful for our patients, please click here.

4.9	One star One star One star One star One half star	Provider showed concern
4.9	One star One star One star One star One half star	Provider explained things clearly
4.8	One star One star One star One star One half star	Provider discussed treatment options
4.9	One star One star One star One star One half star	Provider included you in decisions
4.9	One star One star One star One star One half star	Likelihood of recommending this provider

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One star One star One star One star One star	05/15/2025	My situation in its entirety was evaluated by Drs. Bryan Webb and Shu. I felt seen and heard by both providers. They are the epitome of caring health providers I would see again and recommend and help others seek.
One star One star One star One star One star	04/15/2025	Dr. Shu was AWESOME! Methodically, Dr. Shu explained the MRIs and other issues to my understanding. When my visit ended with Dr. Shu, I gained renewed hope in my health prospects. THANK YOU DR. Shu. Thank you.
One star One star One star One star One star	03/30/2025	Unquestionable Expertise and and a excellent Doctor that knows what he is doing to help you with your progression.
One star One star One star One star One star	02/08/2025	Excellent experience.
One star One star One star One star One star	02/07/2025	Dr Shu makes me comfortable and explain clearly so I understand what the situation is
One star One star One star One star One star	01/04/2025	I'm an Emory fan
One star One star One star One star One star	12/24/2024	Shu MD was thorough, detailed and proactive with my medical care!
One star One star One star One star One star	12/12/2024	Excellent
One star One star One star One star One star	11/16/2024	Good
One star One star One star One star One star	09/28/2024	Dr Shu was over the top w/ concern, explaining cause and effect, outlining treatment, testing, when he would f/up
One star One star One star One star One star	09/04/2024	Dr. Shu was so patient. He answered all my questions. I was so nervous and for the first time since being told I had cancer, he put my mind at ease a bit.
One star One star One star One star One star	08/10/2024	Dr. Shu, is a brilliant, talented, compassionate physician.
One star One star One star One star One star	08/07/2024	Good
One star One star One star One star Empty star	08/01/2024	My provider was not in but Dr Shu was very nice.
One star One star One star One star One star	07/26/2024	Doctor Shu has excellent bedside manners! He is kind, attentive, knowledgeable, makes his patients feel heard and that they are his top priority. Doctor Shu goes above and beyond and his patient's health and recovery is extremely important to him!
One star One star One star One star One star	07/26/2024	They were great and highly recommend
One star One star One star One star Empty star	07/13/2024	We brought along a cd with last MRI images. They had to leave consult to find it and upload images. Added to the very long wait, and I'm not sure the Dr ever saw the images. Disappointing
One star One star One star One star One star	06/12/2024	Listened to my concerns. Open to my questions. Took his time with me.