M. Neale Weitzmann, PhD
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Research Program
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Email Address
M. Neale Weitzmann, PhD, is Professor of Medicine and an associate director of the Bone Laboratory in the Division of Endocrinology and Metabolism at Emory University School of Medicine. Dr. Weitzmann is also a research biologist at the Department of Veterans Affairs, Atlanta VA Medical Center. He is a member of the Discovery and Developmental Therapeutics Research Program at Winship Cancer Institute. Dr. Weitzmann received his PhD in Medical Biochemistry from Medical School, University of the Witwatersrand at Johannesburg, South Africa. His postdoctoral training included a fellowship in the Laboratory of Molecular and Cellular Biology at the National Institutes of Health in Bethesda, MD. He also completed a fellowship in the Department of Internal Medicine at the Washington University School of Medicine in St. Louis, MO.Education
Dr. Weitzmann's research focus centers on metabolic bone disease and the mechanisms that drive bone loss in multiple pathological conditions including rheumatoid arthritis, aging, postmenopausal osteoporosis, HIV-infection, antiretroviral therapy and cancer metastases to bone.
Title/Journal | Authors | Publication Date |
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Gender-affirming hormone therapy preserves skeletal maturation in young mice via the gut microbiome. The Journal of clinical investigation |
S Pal, X Morgan, HY Dar, CA Gacasan, S Patil, A Stoica, YJ Hu, MN Weitzmann, RM Jones, R Pacifici | 03/26/2024 |
Prostaglandins, leukotrienes, and essential fatty acids |
PC Nesbeth, TR Ziegler, AK Tripathi, S Dabeer, D Weiss, L Hao, MR Smith, DP Jones, KM Maner-Smith, CL Tu, W Chang, MN Weitzmann, JA Alvarez | 02/01/2024 |
eLife |
H Zheng, Q Li, S Li, Z Li, M Brotto, D Weiss, D Prosdocimo, C Xu, A Reddy, M Puchowicz, X Zhao, MN Weitzmann, MK Jain, CK Qu | 09/06/2023 |
Callus γδ T cells and microbe-induced intestinal Th17 cells improve fracture healing in mice. The Journal of clinical investigation |
HY Dar, DS Perrien, S Pal, A Stoica, S Uppuganti, JS Nyman, RM Jones, MN Weitzmann, R Pacifici | 04/17/2023 |
Hormone therapy and fractures in postmenopausal women. AIDS (London, England) |
MT Yin, DR Hoover, Q Shi, PC Tien, MH Cohen, S Kassaye, D Gustafson, A Adimora, MN Weitzmann, H Bolivar, A Warriner, SH Bares, A Sharma | 10/01/2022 |
Immune Reconstitution Bone Loss Exacerbates Bone Degeneration Due to Natural Aging in a Mouse Model. The Journal of infectious diseases |
MN Weitzmann, D Weiss, T Vikulina, S Roser-Page, K Yu, ME McGee-Lawrence, CL Tu, W Chang, I Ofotokun | 08/12/2022 |
JBMR plus |
S Roser-Page, D Weiss, T Vikulina, M Yu, R Pacifici, MN Weitzmann | 07/01/2022 |
The Journal of clinical investigation |
S Pal, DS Perrien, T Yumoto, R Faccio, A Stoica, J Adams, CM Coopersmith, RM Jones, MN Weitzmann, R Pacifici | 06/15/2022 |
Immunity & ageing : I & A |
J Chen, K Titanji, AN Sheth, R Gandhi, D McMahon, I Ofotokun, MN Weitzmann, K De Paris, JB Dumond | 01/03/2022 |
PloS one |
CC Mehta, KS Hagen, AA Rubtsova, CD Lahiri, V Michopoulos, CA Moran, LB Haddad, K Titanji, LF Collins, AA Quyyumi, G Neigh, LJ Shaw, MN Weitzmann, L Waller, I Ofotokun | 01/01/2022 |
Restriction of HIV-1 infection in sickle cell trait. Blood advances |
N Kumari, M Nouraie, A Ahmad, H Lassiter, J Khan, S Diaz, N Afangbedji, S Wang, PE Houston, T Ammosova, M de Mulder Rougvie, S Rana, DF Nixon, K Anastos, J Lazar, AL French, S Gange, AA Adimora, MN Weitzmann, M Fischl, MC Kempf, S Kassaye, JG Taylor, S Nekhai | 12/14/2021 |
The Journal of clinical investigation |
M Yu, S Pal, CW Paterson, JY Li, AM Tyagi, J Adams, CM Coopersmith, MN Weitzmann, R Pacifici | 02/15/2021 |
Clinical nutrition (Edinburgh, Scotland) |
MP Bellissimo, TR Ziegler, DP Jones, KH Liu, J Fernandes, JL Roberts, MN Weitzmann, R Pacifici, JA Alvarez | 02/01/2021 |
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America |
I Ofotokun, LF Collins, K Titanji, A Foster, CA Moran, AN Sheth, CD Lahiri, JL Lennox, L Ward, KA Easley, MN Weitzmann | 10/23/2020 |
Metabolomic Associations with Serum Bone Turnover Markers. Nutrients |
MP Bellissimo, JL Roberts, DP Jones, KH Liu, KR Taibl, K Uppal, MN Weitzmann, R Pacifici, H Drissi, TR Ziegler, JA Alvarez | 10/16/2020 |
AIDS (London, England) |
K Titanji, I Ofotokun, MN Weitzmann | 08/01/2020 |
Parathyroid hormone-dependent bone formation requires butyrate production by intestinal microbiota. The Journal of clinical investigation |
JY Li, M Yu, S Pal, AM Tyagi, H Dar, J Adams, MN Weitzmann, RM Jones, R Pacifici | 04/01/2020 |
PTH induces bone loss via microbial-dependent expansion of intestinal TNF+ T cells and Th17 cells. Nature communications |
M Yu, A Malik Tyagi, JY Li, J Adams, TL Denning, MN Weitzmann, RM Jones, R Pacifici | 01/24/2020 |
Blood advances |
MN Weitzmann, S Roser-Page, T Vikulina, D Weiss, L Hao, WH Baldwin, K Yu, N Del Mazo Arbona, ME McGee-Lawrence, SL Meeks, CL Kempton | 02/12/2019 |
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research |
JY Li, M Yu, AM Tyagi, C Vaccaro, E Hsu, J Adams, T Bellido, MN Weitzmann, R Pacifici | 02/01/2019 |
Immunity |
AM Tyagi, M Yu, TM Darby, C Vaccaro, JY Li, JA Owens, E Hsu, J Adams, MN Weitzmann, RM Jones, R Pacifici | 12/18/2018 |
Rheumatology (Oxford, England) |
S Roser-Page, T Vikulina, K Yu, ME McGee-Lawrence, MN Weitzmann | 06/01/2018 |
AIDS (London, England) |
K Titanji, A Vunnava, A Foster, AN Sheth, JL Lennox, A Knezevic, N Shenvi, KA Easley, I Ofotokun, MN Weitzmann | 04/24/2018 |
Annals of the New York Academy of Sciences |
S Roser-Page, T Vikulina, D Weiss, MM Habib, GR Beck, R Pacifici, TF Lane, MN Weitzmann | 03/01/2018 |
EMBO reports |
M Yu, P D'Amelio, AM Tyagi, C Vaccaro, JY Li, E Hsu, I Buondonno, F Sassi, J Adams, MN Weitzmann, R DiPaolo, R Pacifici | 01/01/2018 |
The Journal of infectious diseases |
MN Weitzmann, T Vikulina, S Roser-Page, M Yamaguchi, I Ofotokun | 11/27/2017 |
Toxicologic pathology |
MN Weitzmann | 10/01/2017 |
Molecular and cellular biochemistry |
M Yamaguchi, S Osuka, M Shoji, MN Weitzmann, T Murata | 06/01/2017 |
Current treatment options in infectious diseases |
CA Moran, MN Weitzmann, I Ofotokun | 03/01/2017 |
Persistence of Vascular Calcification after Reversal of Uremia. The American journal of pathology |
KA Lomashvili, KE Manning, MN Weitzmann, V Nelea, MD McKee, WC O'Neill | 02/01/2017 |
GNB3 overexpression causes obesity and metabolic syndrome. PloS one |
AC Ozdemir, GM Wynn, A Vester, MN Weitzmann, GN Neigh, S Srinivasan, MK Rudd | 01/01/2017 |
Bone Loss Among Women Living With HIV. Current HIV/AIDS reports |
MN Weitzmann, I Ofotokun, K Titanji, A Sharma, MT Yin | 12/01/2016 |
International journal of oncology |
M Yamaguchi, S Osuka, MN Weitzmann, BF El-Rayes, M Shoji, T Murata | 10/01/2016 |
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America |
I Ofotokun, K Titanji, CD Lahiri, A Vunnava, A Foster, SE Sanford, AN Sheth, JL Lennox, A Knezevic, L Ward, KA Easley, P Powers, MN Weitzmann | 09/01/2016 |
Physiological and pathophysiological bone turnover - role of the immune system. Nature reviews. Endocrinology |
MN Weitzmann, I Ofotokun | 09/01/2016 |
AIDS (London, England) |
ES Chan, AL Landay, TT Brown, HJ Ribaudo, P Mirmonsef, I Ofotokun, MN Weitzmann, J Martinson, KL Klingman, JJ Eron, CJ Fichtenbaum, J Plants, BO Taiwo | 08/24/2016 |
International journal of oncology |
M Yamaguchi, S Osuka, MN Weitzmann, M Shoji, T Murata | 08/01/2016 |
The protease inhibitors and HIV-associated bone loss. Current opinion in HIV and AIDS |
CA Moran, MN Weitzmann, I Ofotokun | 05/01/2016 |
International journal of oncology |
M Yamaguchi, S Osuka, MN Weitzmann, BF El-Rayes, M Shoji, T Murata | 05/01/2016 |
Expression of SOFAT by T- and B-lineage cells may contribute to bone loss. Molecular medicine reports |
CR Jarry, EF Martinez, DC Peruzzo, V Carregaro, LA Sacramento, VC Araújo, MN Weitzmann, MH Napimoga | 05/01/2016 |
AIDS (London, England) |
I Ofotokun, K Titanji, A Vunnava, S Roser-Page, T Vikulina, F Villinger, K Rogers, AN Sheth, CD Lahiri, JL Lennox, MN Weitzmann | 01/28/2016 |
Cell metabolism |
JY Li, P D'Amelio, J Robinson, LD Walker, C Vaccaro, T Luo, AM Tyagi, M Yu, M Reott, F Sassi, I Buondonno, J Adams, MN Weitzmann, GC Isaia, R Pacifici | 11/03/2015 |
International journal of oncology |
M Yamaguchi, T Murata, M Shoji, MN Weitzmann | 10/01/2015 |
Oncology reports |
M Yamaguchi, T Vikulina, MN Weitzmann | 10/01/2015 |
Role of T-cell reconstitution in HIV-1 antiretroviral therapy-induced bone loss. Nature communications |
I Ofotokun, K Titanji, T Vikulina, S Roser-Page, M Yamaguchi, M Zayzafoon, IR Williams, MN Weitzmann | 09/22/2015 |
Bioactive silica nanoparticles reverse age-associated bone loss in mice. Nanomedicine : nanotechnology, biology, and medicine |
MN Weitzmann, SW Ha, T Vikulina, S Roser-Page, JK Lee, GR Beck | 05/01/2015 |
T cell-expressed CD40L potentiates the bone anabolic activity of intermittent PTH treatment. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research |
JW Robinson, JY Li, LD Walker, AM Tyagi, MA Reott, M Yu, J Adams, MN Weitzmann, R Pacifici | 04/01/2015 |
Molecular and cellular biochemistry |
M Yamaguchi, S Zhu, MN Weitzmann, JP Snyder, M Shoji | 03/01/2015 |
Body composition and grip strength are improved in transgenic sickle mice fed a high-protein diet. Journal of nutritional science |
PL Capers, HI Hyacinth, S Cue, P Chappa, T Vikulina, S Roser-Page, MN Weitzmann, DR Archer, GW Newman, A Quarshie, JK Stiles, JM Hibbert | 01/01/2015 |
T-cells and B-cells in osteoporosis. Current opinion in endocrinology, diabetes, and obesity |
MN Weitzmann | 12/01/2014 |
PLoS pathogens |
K Titanji, A Vunnava, AN Sheth, C Delille, JL Lennox, SE Sanford, A Foster, A Knezevic, KA Easley, MN Weitzmann, I Ofotokun | 10/01/2014 |
ACS nano |
SW Ha, MN Weitzmann, GR Beck | 06/24/2014 |
CTLA-4Ig-induced T cell anergy promotes Wnt-10b production and bone formation in a mouse model. Arthritis & rheumatology (Hoboken, N.J.) |
S Roser-Page, T Vikulina, M Zayzafoon, MN Weitzmann | 04/01/2014 |
Toxicology in vitro : an international journal published in association with BIBRA |
SW Ha, JA Sikorski, MN Weitzmann, GR Beck | 04/01/2014 |
Current molecular medicine |
M Yamaguchi, T Vikulina, JL Arbiser, MN Weitzmann | 01/01/2014 |
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research |
JY Li, LD Walker, AM Tyagi, J Adams, MN Weitzmann, R Pacifici | 01/01/2014 |
B Cell Production of Both OPG and RANKL is Significantly Increased in Aged Mice. The Open bone journal |
Y Li, M Terauchi, T Vikulina, S Roser-Page, MN Weitzmann | 01/01/2014 |
Journal of investigative medicine : the official publication of the American Federation for Clinical Research |
S Adeel, K Singh, KH Vydareny, M Kumari, E Shah, MN Weitzmann, V Tangpricha | 12/01/2013 |
Blood |
JY Li, J Adams, LM Calvi, TF Lane, MN Weitzmann, R Pacifici | 10/03/2013 |
The Journal of biological chemistry |
Z Wang, MN Weitzmann, S Sangadala, WC Hutton, ST Yoon | 09/27/2013 |
Do γδ T cells predict osteonecrosis of the jaw? Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research |
MN Weitzmann | 04/01/2013 |
Scientifica |
MN Weitzmann | 01/01/2013 |
PTH expands short-term murine hemopoietic stem cells through T cells. Blood |
JY Li, J Adams, LM Calvi, TF Lane, R DiPaolo, MN Weitzmann, R Pacifici | 11/22/2012 |
International journal of molecular medicine |
M Yamaguchi, MN Weitzmann | 09/01/2012 |
Nanomedicine : nanotechnology, biology, and medicine |
GR Beck, SW Ha, CE Camalier, M Yamaguchi, Y Li, JK Lee, MN Weitzmann | 08/01/2012 |
High dose 1,25(OH)2D3 inhibits osteoblast mineralization in vitro. International journal of molecular medicine |
M Yamaguchi, MN Weitzmann | 05/01/2012 |
Proceedings of the National Academy of Sciences of the United States of America |
B Bedi, JY Li, H Tawfeek, KH Baek, J Adams, SS Vangara, MK Chang, M Kneissel, MN Weitzmann, R Pacifici | 03/20/2012 |
Current HIV/AIDS reports |
I Ofotokun, E McIntosh, MN Weitzmann | 03/01/2012 |
Molecular and cellular biochemistry |
M Yamaguchi, MN Weitzmann, T Murata | 01/01/2012 |
Molecular and cellular biochemistry |
M Yamaguchi, MN Weitzmann | 01/01/2012 |
Honokiol stimulates osteoblastogenesis by suppressing NF-κB activation. International journal of molecular medicine |
M Yamaguchi, JL Arbiser, MN Weitzmann | 12/01/2011 |
Quercetin, a potent suppressor of NF-κB and Smad activation in osteoblasts. International journal of molecular medicine |
M Yamaguchi, MN Weitzmann | 10/01/2011 |
A new regulator of osteoclastogenesis: estrogen response element-binding protein in bone. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research |
H Chen, LC Gilbert, X Lu, Z Liu, S You, MN Weitzmann, MS Nanes, J Adams | 10/01/2011 |
Molecular and cellular biochemistry |
M Yamaguchi, MN Weitzmann | 09/01/2011 |
Discovery medicine |
I Ofotokun, MN Weitzmann | 05/01/2011 |
Cancer research |
S Josson, T Nomura, JT Lin, WC Huang, D Wu, HE Zhau, M Zayzafoon, MN Weizmann, M Gururajan, LW Chung | 04/01/2011 |
Proceedings of the National Academy of Sciences of the United States of America |
JY Li, H Tawfeek, B Bedi, X Yang, J Adams, KY Gao, M Zayzafoon, MN Weitzmann, R Pacifici | 01/11/2011 |
International journal of molecular medicine |
M Yamaguchi, MN Weitzmann | 01/01/2011 |
HIV-1 infection and antiretroviral therapies: risk factors for osteoporosis and bone fracture. Current opinion in endocrinology, diabetes, and obesity |
I Ofotokun, MN Weitzmann | 12/01/2010 |
Disruption of PTH receptor 1 in T cells protects against PTH-induced bone loss. PloS one |
H Tawfeek, B Bedi, JY Li, J Adams, T Kobayashi, MN Weitzmann, HM Kronenberg, R Pacifici | 08/20/2010 |
Alterations in the immuno-skeletal interface drive bone destruction in HIV-1 transgenic rats. Proceedings of the National Academy of Sciences of the United States of America |
T Vikulina, X Fan, M Yamaguchi, S Roser-Page, M Zayzafoon, DM Guidot, I Ofotokun, MN Weitzmann | 08/03/2010 |
Inhibition of antigen presentation and T cell costimulation blocks PTH-induced bone loss. Annals of the New York Academy of Sciences |
B Bedi, JY Li, F Grassi, H Tawfeek, MN Weitzmann, R Pacifici | 03/01/2010 |
International journal of molecular medicine |
M Yamaguchi, MN Weitzmann | 11/01/2009 |
T lymphocytes amplify the anabolic activity of parathyroid hormone through Wnt10b signaling. Cell metabolism |
M Terauchi, JY Li, B Bedi, KH Baek, H Tawfeek, S Galley, L Gilbert, MS Nanes, M Zayzafoon, R Guldberg, DL Lamar, MA Singer, TF Lane, HM Kronenberg, MN Weitzmann, R Pacifici | 09/01/2009 |
International journal of molecular medicine |
M Yamaguchi, MN Weitzmann | 02/01/2009 |
Molecular medicine reports |
M Yamaguchi, MN Weitzmann | 01/01/2009 |
T cells potentiate PTH-induced cortical bone loss through CD40L signaling. Cell metabolism |
Y Gao, X Wu, M Terauchi, JY Li, F Grassi, S Galley, X Yang, MN Weitzmann, R Pacifici | 08/01/2008 |
Suppression of NF-kappaB activation blocks osteoclastic bone resorption during estrogen deficiency. International journal of molecular medicine |
K Strait, Y Li, DL Dillehay, MN Weitzmann | 04/01/2008 |