Lindsey Seldin, PhD

Research Program

Cell and Molecular Biology
Email Address

lseldin@emory.edu

Biography

Lindsey Seldin, PhD, is an assistant professor in the Department of Cell Biology with a joint appointment in the Department of Dermatology at Emory University School of Medicine. Dr. Seldin is a member of the Cell and Molecular Biology Research Program at Winship Cancer Institute of Emory University.

Education

Dr. Seldin earned her PhD in Cell Biology from Duke University in in Durham, North Carolina. She completed her postdoctoral research on epithelial stem cell plasticity at Vanderbilt University in Nashville, Tennessee.

Titles & Roles

Assistant Professor, Department of Cell Biology

Emory University School of Medicine

Research

The Seldin Lab seeks to understand mechanisms that regulate epithelial stem cell fate during development, homeostasis, and tumorigenesis in the mammalian epidermis and its sub-appendages (including the hair follicle and mammary gland). To investigate these mechanisms at the tissue, cell and molecular levels, we apply in vivo (mouse transgenics, lineage-tracing), ex vivo (3D organotypic culture), imaging (intravital, live, confocal) and RNA sequencing technologies. The broader goal of our research is to inform the development of effective, targeted approaches for regenerative medicine and the treatment of epidermal disease.

Publications

Title/Journal	Authors	Publication Date
Epidermal growth factor dampens pro-inflammatory gene expression induced by interferon-gamma in global transcriptome analysis of keratinocytes. BMC genomics	DC Gibbs, MR McCrary, CS Moreno, L Seldin, C Li, NAH Kamili, BP Pollack	02/10/2025
Noncanonical functions of adhesion proteins in inflammation. American journal of physiology. Cell physiology	R Wang, RR Shu, L Seldin	09/01/2024
Obesity-induced dysregulation of skin-resident PPARγ⁺ Treg cells promotes IL-17A-mediated psoriatic inflammation. Immunity	P Sivasami, C Elkins, PP Diaz-Saldana, K Goss, A Peng, M Hamersky, J Bae, M Xu, BP Pollack, EM Horwitz, CD Scharer, L Seldin, C Li	08/08/2023
Streamlined Intravital Imaging Approach for Long-Term Monitoring of Epithelial Tissue Dynamics on an Inverted Confocal Microscope. Journal of visualized experiments : JoVE	M Hamersky, K Tekale, LM Winfree, MJM Rowan, L Seldin	06/30/2023
Streamlined intravital imaging approach for long-term monitoring of epithelial tissue dynamics on an inverted confocal microscope. bioRxiv : the preprint server for biology	M Hamersky, K Tekale, LM Winfree, MJ Rowan, L Seldin	05/12/2023
Preprint Highlight: Force-dependent recruitment of Piezo1 drives adhesion maturation and calcium entry in normal but not tumor cells. Molecular biology of the cell	L Seldin	12/01/2022
Preprint Highlight: Cytoplasmic forces functionally reorganize nuclear condensates in oocytes. Molecular biology of the cell	L Seldin	09/01/2022
Preprint Highlight: PGC1α regulates the endothelial response to fluid shear stress via telomerase reverse transcriptase control of heme oxygenase-1. Molecular biology of the cell	L Seldin	07/01/2022
Commentary: DNA Damage Promotes Epithelial Hyperplasia and Fate Mis-specification via Fibroblast Inflammasome Activation. Journal of dermatology and skin science	D Solano, KR Patel, AB Perez, L Seldin	01/01/2022