Linsheng Zhang, MD, PhD

Role

Pathology
Specialty

Leukemia Lymphoma Myeloma and Plasma Cell Disorders Myelodysplastic Syndromes
Research Program

Cell and Molecular Biology
Practicing Since

2011

Background

Linsheng Zhang, MD, PhD is an associate professor in the Department of Pathology & Laboratory Medicine at Emory University School of Medicine. Dr. Zhang's specializes in diagnostic hematopathology integrating morphologic examination, flow cytometric immunophenotyping, cytogenetics, FISH, and microarray studies; and molecular diagnosis of solid tumors. He serves as an attending physician on the Hematopathology and Molecular Diagnostic Laboratory service at Emory University Hospital.

Dr. Zhang received his MD from Third Military Medical University in Chongqing, China in 1986 and his PhD from Institute of Hematology at Beijing Medical University in China in 1995. He completed his Residency in Anatomic and Clinical Pathology from the Medical University of South Carolina in 2011. At Emory University, Dr. Zhang completed fellowships in hematopathology and molecular genetic pathology in 2012 and 2013 respectively.

Dr. Zhang's research interest is in the genetic profiling of hematologic malignancies including myeloid neoplasms, lymphomas, multiple myeloma, and solid tumors, especially lung cancer and melanoma, using high resolution microarray, RNA-seq, and panel gene sequencing, aiming at bringing these into clinical laboratory as routine diagnostic tests.

PubMed

Titles & Roles

Associate Professor, Department of Pathology and Laboratory Medicine

Emory University School of Medicine

Education & Training

Education

Fellowship, Molecular Genetic Pathology, 2013
Emory University School of Medicine
Fellowship, Hematology, 2012
Emory University School of Medicine
Residency, Pathology-Anatomic, 2011
Medical University of South Carolina
Fellowship, 2003
Uniformed Services Univ of Hlth Sciences
Medical Education, MD, 1986
Third Military Medical University, China

Board Certifications

Molecular Genetic Pathology
American Board of Pathology, 2013
Hematology
American Board of Pathology, 2012
Clinical Pathology
American Board of Pathology, 2011
Anatomic Pathology
American Board of Pathology, 2011

Research

Publications

Title/Journal	Authors	Publication Date
Association of Residential Segregation with Mortality in the U.S., 2018-2022. American journal of preventive medicine	L Zhang, NN Yang, T Shen, X Sun, KR Yabroff, X Han	01/15/2025
TP53 mutations in myeloid neoplasms: implications for accurate laboratory detection, diagnosis, and treatment. Laboratory medicine	L Zhang, B Abro, A Campbell, Y Ding	11/04/2024
Extracavitary primary effusion lymphoma presenting as a solitary brain mass. CNS oncology	T Javadi, B Morales, JJ Olson, S Kothari, L Zhang, M Abedalthagafi	06/06/2024
EBV-Positive Nodal T- and NK-Cell Lymphoma Mimicking Anaplastic Large Cell Lymphoma: A Case Report. Hematology reports	B Abro, P Allen, S Asakrah, K Bradley, L Zhang	05/23/2024
Measurable (Minimal) Residual Disease in Myelodysplastic Neoplasms (MDS): Current State and Perspectives. Cancers	L Zhang, G Deeb, KK Deeb, C Vale, D Peker Barclift, N Papadantonakis	04/15/2024
Genetic Profiling of African American Patients With Prostatic Adenocarcinoma Metastatic to the Lymph Nodes: A Pilot Study. Archives of pathology & laboratory medicine	S Bidot, J Yin, P Zhou, L Zhang, KK Deeb, G Smith, CE Hill, J Xiu, MA Bilen, KB Case, M Tinsley, B Carthon, LR Harik	03/01/2024
Molecular Genetic Profile of Myelofibrosis: Implications in the Diagnosis, Prognosis, and Treatment Advancements. Cancers	T Verma, N Papadantonakis, D Peker Barclift, L Zhang	01/25/2024
Bilateral breast Rosai-Dorfman disease screen detected by mammography. Clinical case reports	C Sumner, K Salem, L Abunimer, A Ewaz, L Zhang, A Monsrud, N Calisi	03/01/2023
Essential Thrombocythemia and Post-Essential Thrombocythemia Myelofibrosis: Updates on Diagnosis, Clinical Aspects, and Management. Laboratory medicine	OC Puglianini, D Peker, L Zhang, N Papadantonakis	01/05/2023
Revealing molecular architecture of FLT3 internal tandem duplication: Development and clinical validation of a web-based application to generate accurate nomenclature. International journal of laboratory hematology	Y Ding, GH Smith, K Deeb, T Schneider, A Campbell, L Zhang	10/01/2022
Comment on "A Novel COL1A1-CAMTA1 Rearrangement in Cranial Fasciitis". International journal of surgical pathology	KK Deeb, S Li, L Zhang	10/01/2022
Update on the Classification of and Diagnostic Approaches to Mature T-Cell Lymphomas. Archives of pathology & laboratory medicine	X Zhang, J Zhou, X Han, E Wang, L Zhang	08/01/2022
Stable flow-induced expression of KLK10 inhibits endothelial inflammation and atherosclerosis. eLife	D Williams, M Mahmoud, R Liu, A Andueza, S Kumar, DW Kang, J Zhang, I Tamargo, N Villa-Roel, KI Baek, H Lee, Y An, L Zhang, EW Tate, P Bagchi, J Pohl, LO Mosnier, EP Diamandis, K Mihara, MD Hollenberg, Z Dai, H Jo	01/11/2022
Metastatic low-grade endometrial stromal sarcoma after 24 years: A case report and review of recent molecular genetics. Diagnostic cytopathology	AE Mindiola-Romero, X Liu, JL Dillon, M Talarico, G Smith, L Zhang, K Linos	03/01/2021
Primary cutaneous Ewing sarcoma with diffuse S100/SOX10 positivity and pseudoalveolar pattern: An extraordinarily rare case highlighting a potential pitfall with significant repercussions. Journal of cutaneous pathology	Z Evangelou, L Zhang, LJ Tafe, L Azzouz, Z Grada, K Linos	02/01/2021
Mantle Cell Lymphoma With Mantle Zone Growth Pattern. American journal of clinical pathology	J Yuan, S Li, X Liu, RJ Su, M Chen, X Wu, G Zheng, LM Smith, L Wang, Y Li, C Liu, J Zhou, Q Shen, L Zhang, E Wang, ML Xu, Z Pan	07/05/2019
A novel case of an aggressive superficial spindle cell sarcoma in an adult resembling fibrosarcomatous dermatofibrosarcoma protuberans and harboring an EML4-NTRK3 fusion. Journal of cutaneous pathology	N Olson, O Rouhi, L Zhang, C Angeles, J Bridge, D Lopez-Terrada, T Royce, K Linos	12/01/2018
EML4-ALK Rearrangement and Its Therapeutic Implications in Inflammatory Myofibroblastic Tumors. The oncologist	F Vargas-Madueno, E Gould, R Valor, N Ngo, L Zhang, MA Villalona-Calero	10/01/2018
Validation of a Customized Bioinformatics Pipeline for a Clinical Next-Generation Sequencing Test Targeting Solid Tumor-Associated Variants. The Journal of molecular diagnostics : JMD	T Schneider, GH Smith, MR Rossi, CE Hill, L Zhang	05/01/2018
Multimodality Technologies in the Assessment of Hematolymphoid Neoplasms. Archives of pathology & laboratory medicine	S Li, DL Jaye, KT Bradley, L Zhang, D Saxe, G Deeb, CE Hill, KP Mann	03/01/2017
Multi-Institutional FASTQ File Exchange as a Means of Proficiency Testing for Next-Generation Sequencing Bioinformatics and Variant Interpretation. The Journal of molecular diagnostics : JMD	KD Davies, MS Farooqi, M Gruidl, CE Hill, J Woolworth-Hirschhorn, H Jones, KL Jones, A Magliocco, M Mitui, PH O'Neill, R O'Rourke, NM Patel, D Qin, E Ramos, MR Rossi, TM Schneider, GH Smith, L Zhang, JY Park, DL Aisner	07/01/2016
Clinical Validation and Implementation of a Targeted Next-Generation Sequencing Assay to Detect Somatic Variants in Non-Small Cell Lung, Melanoma, and Gastrointestinal Malignancies. The Journal of molecular diagnostics : JMD	KE Fisher, L Zhang, J Wang, GH Smith, S Newman, TM Schneider, RN Pillai, RR Kudchadkar, TK Owonikoko, SS Ramalingam, DH Lawson, KA Delman, BF El-Rayes, MM Wilson, HC Sullivan, AS Morrison, S Balci, NV Adsay, AA Gal, GL Sica, DF Saxe, KP Mann, CE Hill, FR Khuri, MR Rossi	03/01/2016
Clinical significance of quantitative monitoring and mutational analysis of BCR-ABL1 transcript in Philadelphia chromosome positive B lymphoblastic leukemia. Leukemia & lymphoma	L Zhang, RT Ramjit, CE Hill, M Arellano, HJ Khoury, KP Mann	02/01/2016
Development and validation of CALR mutation testing for clinical diagnosis. American journal of clinical pathology	CL Maier, KE Fisher, HH Jones, CE Hill, KP Mann, L Zhang	11/01/2015
Systemic mastocytosis with associated myeloproliferative neoplasm with t(8;19)(p12;q13.1) and abnormality of FGFR1: report of a unique case. International journal of clinical and experimental pathology	CB Duckworth, L Zhang, S Li	01/01/2014

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